The invention discloses a linkage roller carrying mechanism which comprises a worm gear reducer, a handwheel, a link mechanism, a plurality of roller carrying support fixing plates, a plurality of roller carrying supports, a plurality of carrier roller revolving shafts, a series rod and a plurality of carrier rollers, the plurality of roller carrying supports are respectively installed on the plurality of roller carrying support fixing plates and are connected with the roller carrying support fixing plates through pins, the plurality of carrier roller revolving shafts are respectively installed on the plurality of roller carrying supports, the plurality of carrier rollers are respectively installed on the carrier roller revolving shafts, each of the roller carrying supports comprises an active roller carrying support and a plurality of driven roller carrying supports, the active roller carrying support is connected with the link mechanism, and the active roller carrying support is connected with the plurality of driven roller carrying supports through the series rod. The linkage roller carrying mechanism provided by the invention has a simple structure, is convenient to operate, substantially alleviates labor intensity of workers and improves production efficiency.


Titanium alloy bellows has advantages of light weight, excellent mechanical property, good heat resistance and corrosion resistance, etc. But the cold formability of titanium alloy is poor, so it is difficult to manufacture titanium alloy bellows by traditional mechanical forming and hydroforming. In this paper, current assisted superplastic forming technology was used to process titanium alloy bellows, which could overcome some shortcomings of traditional superplastic forming effectively, such as slow heating rate, high energy loss and low production efficiency. And titanium alloy bellows formed by this technology is of good quality with uniform wall thickness, light oxidation.


This article is an attempt to present new directions for understanding Mouloud Feraoun's La terre et le sang (1953). By considering Walter Benjamin's theoretical reflections, with a particular interest in his concept of «Storytelling », the task is to show that Feraoun can neither be regarded simply as a transmitter and a translator of the popular verb nor the reproducer of specific cultural patterns, but an artist with a rich and fertile imagination. The present paper examines the novel as an embodiment of the community-created culture and counter-colonial discourse making of its author a self-assertive community agent with the potential for forging a new historically informed identity. Résumé Le présent article propose une lecture du roman La terre et le sang (1953) de Mouloud Feraoun afin de montrer que l'auteur n'est pas uniquement un simple agent qui transmet et qui traduit le verbe populaire, encore moins le reproducteur de schémas culturels distincts. Il paraît tel un artiste doté d'une imagination riche incontestablement inspirée par la tradition orale Kabyle. L'analyse prend son fondement théorique à partir des stratégies discursives initiées par Walter Benjamin (1892-1940), une figure singulière de la pensée critique contemporaine. It is said that a young man collected stories from everyone he met but he never shared in return. Instead, he placed what he gathered into a bag which he secreted away in his closet. One day, the stories conspired to harm their collector for keeping them to himself. Luckily, a faithful servant found them and started telling:"Stories are meant to be shared and passed on to others" (An old Korean Folktale). Introduction The present article underscores the textual richness and brings to the fore the creative and discursive devices and strategies with which to examine the voice of Feraoun, the storyteller according to the theoretical concept of "storytelling" suggested by Walter Benjamin. It will focus on the teller's voice, which is dynamic in nature, vivid and Mouloud Feraoun's La terre et le Sang. A Fictionalized Tale Dr Nadia GADA 2 vigorous, supple and subtle. It is a voice that is interested in the struggle against colonialism and efforts to overcome its legacy. It provides freedom of expression from one generation to another because it always connects people in good and bad times, and therefore, predisposes the communication focus to be interpersonal Similar to flexible clay in the hand of the skilled potter, it relentlessly expects renovation by the creative tongue and impulse of the verbal artist to re-shape it into even more fascinating forms. This voice has been, so far, not heard by Mouloud Feraoun's literary reviewers, who have not even begun scratching the surface of the enormous complexity and intricacy of the form and content of La terre et sang. Walter Benjamin's Concept of "Storytelling" Storytelling, as the German theorist suggests it, is the act of telling stories based on a "communicable experience", which means, a creative art and method contributing to strengthen and to regulate the auditor's sporadic imagination in new ways that meet his needs as it helps his growth intellectually, socially, spiritually, and emotionally (Benjamin[1936], Zohn.1968:85). As a vocation to which everyone is called to participate, the story teller narrates his stories with an exciting and successful way to help the audience to learn. His stories in which listeners can look within and find deeper meanings that inspire and force them to create their own images (Ibid.95). Storytelling cultivates and promotes the use of memory and imagination in order to reinforce the communication skills and provide the tools with which the listener may effectively settle through life's daily interactions. The advantage of storytelling is not meant to know the story as part of the mental collection, but to feel it because it has a profound purpose to guide and transform human lives. Stories avoid thinking of imagination as a historical activity but as a daily necessity (P.102). Through the experience of storytelling, adds Walter Benjamin, the values and beliefs are easily transmitted in an understandable and memorable way to auditors via oral storytelling. Stories are given voice in a respectful and soulful way and a strong sense of community is created through oral performance as a special bond forms between the teller and what is told. The practitioner of storytelling reminds that the addresses are al1 bound to each other in Mouloud Feraoun's La terre et le Sang. A Fictionalized Tale Dr Nadia GADA 3 some way. He creates the effect of allowing his readers to enter his inner world and share in his persona1 hardships and achievements. Stories connect people from different cultures. This link is exemplified by stories which bridge cultural divides, to teach the audience the need to respect and care for the elders and ancestors. Incorporating the art of storytelling belonging to societal groups also works towards the creation of tolerance in the community. The storyteller speaks a universal language through which he explores not only his own culture but also refers to the culture of other communities and other worlds, concludes the theorist (P.104). Strategies of Storytelling in Fearoun's Novel In Mouloud Feraoun's La terre et le sang, storytelling and the folk tradition forms the backbone of the narrative, which is peppered with myths and legends preserved among common people. Storytelling also occupies a prominent place in Kabyle culture as it affords people the best chances for sharing experience across it. The cultivation of language sensibility takes place in the context of storytelling as a creative activity. It recognizes the value of memory as the key to people's relationship with their past, their heritage and sense of identity, as people tend to remember in the present the things, which in the past had borrowed significance for their existence. The novel's characters speak and weave into the fabric of their everyday conversation with some allusions to folktales, legends, and myths. They support their opinions and attitudes with some appropriately chosen proverbs, traditional maxims and cryptic anecdotes. Their dialogues are chosen from an oral tradition. The non-verbal elements and their functions range from the creation of mood to local color, and Algerian flavor. The writer appeals greatly to the use of oral narratives which, in the words of Jack Goody, contain five aspects of literary forms including epics, myths, legends, folktales, and personal narratives which have many functions and many levels of interpretation. The telling of tales is often thought to be characteristic of all human discourse and it is fashionable to speak of narrative as a universal form of expression, one which is applicable to the life experiences of individuals and to the dramas of social interaction (Goody.2010:122). Mouloud Feraoun's La terre et le Sang. A Fictionalized Tale Dr Nadia GADA 4 However, the question addressed, in the context of our analysis, is for what purpose (s) Feraoun uses the oral legacy of storytelling; and how it is displayed in the narrative. First, the reason of using storytelling is a "strategy" aiming, first and foremost, to rescue the image of his world from European Eurocentric and colonial discourse. The use of some elements from oral tradition becomes a means to reclaim the lost heritage through an appropriate use of the cultural and linguistic tools available to him. The task is done mainly in reviving past history found in oral traditions and the memories of old people. More importantly, Feraoun gives voice to" the voiceless." which stands for the quest for his countrymen's voices. The value accorded to storytelling among other oral sources aims to document the knowledge of his people and to democratize history by representing marginalized people and groups whose voices, memories, and actions were often absent from the official (written) records. In other words storytelling in La terre et le sang is "not only a means of knowledge but also a frame of authority", which can be understood as a message or a testimony transmitted orally from one generation to another. It is also an evidence of his people's pre-colonial past that was absent from dominant colonial histories and narratives. The task of the storyteller in this regard, is to decode the meaning of oral traditions reported to him as "oral statements" (White. Miesche. Cohen 2001: 2). Thus, the appeal to storytelling, therefore, can be seen as a kind of counter-history to those fictional colonial accounts about Feraoun's homeland; it also becomes a kind of therapy to rationalize and counteract the displacement and alienation he experienced during his colonial education. Feraoun went to schools of western education, but his instruction and socialization process started around the family's cooking fires after the evening meals, when all the family assembled to listen and participate in storytelling sessions. He grew up with tales about human beings personified as animals and animated trees, nature and spirits which constitute the largest corpus of the Kabyle oral stories. As a child, he was greatly influenced by the tales that his aunts (Khalti and Nana), used to tell in the nights around the firelight (Kanoun). He was brought up by his aunts who early in life inspired his interest in Mouloud Feraoun's La terre et le Sang. A Fictionalized Tale Dr Nadia GADA 5 Kabyle mythology and folklore, a fact which apparently accounts for the predominance of Kabylian lore in his literary works. In his Le fils du pauvre (1950), the author narrates the traditional folk approach of organizing night stories and riddles around his aunts who usually place themselves at the edge of an audience in a circular formation and start by the traditional formula, "Machaho tlem chaho atidba rabi amussaru", the equivalent in meaning of the English "Once upo


In this paper, we analyze emotions in a story text using an emotion embedding model. Firstly, we collected 144,701 tweets, and each tweet is given an emotional hashtag. Using the emotion hashtag as an emotion label, we built a CNN model for emotion classification. We then extracted the embedding model created during the learning process. We then extracted word embedding layer created during the emotion classification learning process. We defined this as an 'Emotion embedding model', and applied it to classify story text emotions. The story text used in emotion analysis was ROC story data, and those story sentences are classified into eight emotions based on plutchik's emotion model.


This book based on research by the (UK) National Association for Care and Rehabilitation of Offenders (NACRO) Research Unit examines the relationship of unemployment, crime and offenders and the findings suggest that no simple causal relationship could be established. Unemployment certainly is a factor but in a very complex and mdirect way. Otherwise, the authors argue, the court could dispose of the


In this paper we explore the use of parsimonious language models for web retrieval. These models are smaller thus more efficient than the standard language models and are therefore well suited for large-scale web retrieval. We have conducted experiments on four TREC topic sets, and found that the parsimonious language model results in improvement of retrieval effectiveness over the standard language model for all data-sets and measures. In all cases the improvement is significant, and more substantial than in earlier experiments on newspaper/newswire data.


"Three Publics" refer to public infrastructure, public affair s, and public services, which are less developed in rural areas, especially in t he western part of China. This paper uses a case study in Baoshan city, Yunnan P rovince, to discuss six aspects in order to build new mechanisms for a coordinat ed urban and rural socio-economic development


Why are some epistemically suspect beliefs so popular? People high in communion, either because they want to make others happy, or because they want to display their niceness, might be particularly keen to share 'happy thoughts,' beliefs that might make others happy, even if they are epistemically suspect—for instance, that naturopathy works, or that heaven exists. Across six experiments (N = 1596) we found that: (i) people who self-describe as being high on communion (i.e., nice, kind) are more likely to believe and share happier epistemically suspect beliefs, by contrast with people who self-describes as being high on agency (i.e., competent, dominant); (ii) people prefer to share happier beliefs when wishing to appear nice and kind rather than competent and dominant; (iii) sharing happier beliefs does lead to being perceived as nicer and kinder; and (iv) sharing happier beliefs leads to being perceived as less dominant. We also found a consistent positive bias independent of participants' personality, with happier beliefs being more likely to be shared and believed. Overall, these results suggest that some happy epistemically suspect beliefs could become culturally successful because they allow their sender to signal niceness and kindness.


It is generally believed that unconditionally secure quantum bit commitment (QBC) is proven impossible by a "no-go theorem". We point out that the theorem only establishes the existence of a cheating unitary transformation in any QBC scheme secure against the receiver, but this fact alone is not sufficient to rule out unconditionally secure QBC as a matter of principle, because there exists no proof that the cheating unitary transformation must be known to the cheater in all possible cases. In this work, we show how to circumvent the "no-go theorem" and prove that unconditionally secure QBC is in fact possible.


On 13 2019 May, the recently formed IEEE Solid-State Circuits Society (SSCS) Leuven Student Chapter organized the first edition of the Microelectronics Micro Symposium. Speakers from industry and academia came to KU Leuven to give presentations based on the event theme, The Car of the Future. Pieter de Muyter, from IC Sense, kicked off the event with his lecture "Integrated Circuits (IC) Design for Battery Management Systems." He outlined the different current sensing techniques used in automotive applications and presented his company's implementation of a currentsensing IC architecture that complies with functional safety. The second speaker, Wouter Leten from Melexis, gave a presentation on current-sensing ICs using the Hall effect. Leten outlined the main advantages of using this effect for current-sensing applications. These contactless current-sensing ICs have a wide current-sensing range and are implemented in CMOS technology, making them highly cost-effective. Following the first two presentations, a coffee break was held. Speakers and attendees mingled, made connections, and networked over cups of fresh coffee. The third speaker, Bert Moons from Synopsys, presented "Machine Vision for Automotive Applications." He began by introducing convolutional neural networks, the workhorse of modern computer vision, and the main challenges to implementing these networks in embedded systems. He outlined how datadependent processing, quantized processing, parallelism, and sparse processing can be exploited to achieve energy-efficient hardware implementat ions fo r automo tive applications. The f ina l s p e a k e r was Kof i Makinwa, an Antoni van Leeuwenhoek Professor and head of the Microelectronics Department at TU Delft. He concluded the symposium with "Next Generation Temperature Sensors." Makinwa began with an outline on integrated temperature sensors and their applications. He continued with bipolar junct ion transistor (BJT) -based temperature sensing and introduced resistor-based temperature sensors. Digital Object Identifier 10.1109/MSSC.2019.2939699 Date of current version: 18 November 2019


Data Availability in Supporting Smart City Readiness in Surakarta City
The smart city concept is one of the developing concepts in overcoming various urban problems. The concept must be supported by mature implementation guidelines. The preparation of smart city guidelines is based on the readiness of each region. The readiness measurement is carried out with smart city readiness measurements that have been developed by several experts. This study will use compilation of several smart city readiness measurement models to measure smart city readiness in Surakarta City, in order to understand data required and available in Surakarta City Government, data required and available outside Surakarta City Government, and data required but not yet provided by both the City Government and other agencies. The method used in this study is case study with a qualitative approach. Measurement results show that the availability of data and the quality of available data in Surakarta City is quite good. This shows that Surakarta City is ready to develop the smart city concept to overcome various city problems faced.


In a modular system for a fast rechargeable traction battery (1) for an industrial truck having a battery case and a battery (2) with high voltage as an energy storage (14) and with an optionally insertable into the housing voltage converter (5) to an operating voltage of the industrial truck to to provide a discharge port (6) available to the traction battery (1) may be formed at least in a plurality of variants for different operating voltages, with a direct transmission of the voltage of the battery (2) is at least one voltage converter (5) for use or alternatively, a plurality of voltage converters (5) for various operating voltages.


Methods To survey the scholarly position of Yuan Ban(袁班) in the history of Wenbing by systematically analyzing and organizing Wenbing related theories in (證治心傳). Results & Conclusions : In his book, YB suggests concepts such as 'mainly attack upper heater(多 犯上焦)', 'transmission to the nutrient phase(轉入營分)', 'sequential transmission(順傳)', 'abnormal transmission(逆傳)', 'dryness invasion of human body in autumn(秋傷於燥)'. In the history of Wenbing, it has been widely acknowledged that the concept of weiqiyingxiebianzheng(衛氣營血辨證) and abnormal transmission to the pericardium(逆傳心 包) were originally suggested by Ye However, according to the findings of this study, these concepts are traced back to the contents of YB's publication, nearly a century before Ye's time. In addition, YB's discussion on '秋燥' was highly advanced than any other scholar of his time, hinting his influence on medicine thereafter.


Skin infections are a common and widespread ailment among children. While these infections have generally been considered benign, the number requiring overnight hospitalisation for treatment, termed 'serious skin infections', has risen markedly in recent years with the incidence in NZ children thought to be significantly higher than that in children of comparatively developed countries. This study aimed to define serious skin infections and describe their epidemiology in the NZ setting. Increased awareness of serious skin infections has resulted in a number of national and regional reports being released over the past decade. However, the accuracy of these existing skin infection data has been limited by the lack of a consistent and valid case definition. By assessing the screening performance of various case definitions when applied in the setting of 4 years of paediatric admissions to a provincial NZ hospital, a new definition for serious skin infection was produced which improved sensitivity from 61% to 99% with negligible loss in specificity. This new case definition was then applied to national hospitalisation data to identify all 0-14 year old children admitted overnight to a NZ hospital with a serious skin infection between January 1990 and December 2007. During this 18-year period the incidence of infection almost doubled from 294.1/100 000 in 1990 to 562.3/100 000 in 2007. Seasonality showed consistent peaks in late Summer and early Autumn. The highest rates were observed in boys, children under 5 years old, Māori (NZ Indigenous peoples) and Pacific children, those living in deprived neighbourhoods, in urban areas and in Northern districts of the country. Trends over time showed the distribution of disease changed with evidence of worsening ethnic and socioeconomic disparities in infection rates. The highest regional incidence was found in the Tairawhiti (Gisborne) Region, where during the same 18-year period admissions rose even more rapidly from 414.5/100 000 in 1990 to 993.3/100 000 in 2007. A closer comparison of hospitalisation data between Tairawhiti and NZ found ethnic disparities in serious skin infection rates were greater in the Tairawhiti Region than nationally. In addition, the overall disease incidence was significantly higher than that expected even after controlling for differences in the population


The idea of laser isotope enrichment grew from the laser's ability to concentrate its output power in a narrow range of wavelengths. Different isotopes of the same element are very hard or impossible to separate chemically, but the difference in their masses leads to differences in their spectra, which in principle can be used to selectively excite one isotope and isolate it by some photo-induced process. The first proposal came from the Atomic Energy Commission's (AEC's) Mound Laboratories in Miamisburg, Ohio, which in 1961 began a classified investigation of using lasers to enrich the concentration of fissionable uranium-235. Others independently proposed laser uranium enrichment. A company called Radioptics proposed it to the AEC in 1963 and later unsuccessfully sued the AEC for violating their trade secrets. A French group received a patent in France in 1965, and by the time a U.S. version of the patent issued in 1969 the idea was looking attractive. The impetus came from the development of the tunable dye laser and the growth of nuclear power. The U.S. depended on the gaseous diffusion process developed during World War II to enrich U-235 concentration to the levels needed for atomic bombs. Gaseous diffusion is energyintensive, expensive, and raises U-235 concentration only a small amount on each pass. Laser enrichment offered to reduce cost, improve efficiency, and increase recovery of U-235. At the Avco-Everett Research Laboratory, Richard Levy and G. Sargent Janes developed a two-step process to enrich U-235. First a dye laser would selectively excite U-235 atoms in uranium vapor, then an ultraviolet laser would ionize the excited U-235 atoms, so they could be collected [1]. (Figure 1 shows the process.) Avco lacked money to develop the technology, so they formed a joint venture with Exxon Nuclear, hoping to build a private uranium enrichment business. Avco-Everett founder Arthur Kantrowitz initially worried that laser enrichment might open the door to nuclear proliferation. "At first glimpse it seems like it's a garage operation. A garage operation for separating uranium isotopes is a frightening thing," he recalled in a 1985 interview. He imposed special security restrictions but eventually realized "this is not an easy way to make a bomb. It might be an easy way to make 1000 bombs, but it is not a terrorist operation" because of its technical complexity [2]. In 1972 the AEC launched competing laser uranium enrichment projects at its Los Alamos and Livermore laboratories. John Emmett, director of Livermore's laser program, chose to try selective excitation of U-235 atoms in uranium vapor with the relatively well-developed tunable dye laser. That paralleled the Avco approach but was based on earlier work by Ray Kidder of Livermore. They proposed a two-step process, starting with using visible output of a narrow-band dye laser tuned to excite U-235, then ionizing the excited uranium atoms. In early 1973 Livermore hired three developers of the first continuous-wave dye laser from Eastman Kodak, Ben Snavely, Otis Peterson, and Sam Tuccio, to start and manage the program. "It seemed like an exciting thing to do at the time," Snavely recalled many years later, an opinion echoed by the other two. At Los Alamos, Reed Jensen and John Lyman chose to try selective enrichment in UF6, the compound used in gaseous diffusion, which sublimes at about 55 deg Celsius and is easier to handle than uranium vapor. They found a large isotope shift in a 16-μm absorption band of UF6 and discovered that ultraviolet photons could photodissociatiate excited UF6 molecules, precipitating solid UF5 from the gas phase reaction and releasing free fluorine into the gas. Developing 1960–1974


Various parameters relating to digestion of a clover diet in the stomach and intestines were measured by marker techniques in the same weaner lambs at 15, 24 and 40 weeks of age when body weights averaged 18, 29 and 44 kg respectively. Significant small changes were observed with increasing age and body size in the values of several of the parameters measured. Thus at 40 weeks relative to 15 weeks values were higher for (i) crude protein digested in the intestines per unit feed intake (+lo%), (ii) sodium content of rumen liquor and sodium flow from the rumen per unit feed intake (+9%, + 14%), (iii) potassium and chloride contents of abomasal liquor (+ 9 %, + 7 %) and (iv) pH of abomasal digesta (+O.3 pH unit). Values were lower for (v) digestibility of organic matter and cell wall constituents in the whole alimentary tract (c. - 1.8 %), (vi) ammonia content of rumen liquor and ammonia flow from the rumen and abomasum per unit feed intake (- 15% to -20%) and (vii) potassium content of rumen liquor (- 9 %). No changes attributable to age or body size were observed with several paramefers, including (i) rate of production of volatile fatty acids in the rumen per unit feed intake, (ii) rate of absorption of volatile fatty acids from the rumen, (iii) rate of flow of digesta through the stomach per unit feed intake, and (iv) mean residence time of water-soluble marker in the rumen. The results indicate that care needs to be exercised in applying digestion data obtained with adult sheep to the nutrition of the growing weaner lamb.


Abstract The covid-19 pandemic has revived a longstanding, and understudied, trope in American politics: the association of immigrants with disease. There has been a great deal of scholarship on the economic, cultural, and criminal threat frames attached to immigrant groups in media coverage, but little to date has specifically examined how national and local sources have framed covid-19 in the context of immigrant communities. In this paper we analyze the prevalence of two different framings of the pandemic in national and local online news outlets over the first year of the pandemic: immigration as a public health threat to the nation, and covid-19 as a threat to immigrant communities within the nation. We find significant differences between national and local coverage, with the former more likely to frame immigration as a covid-19 threat, while local news outlets were more likely to discuss the threat the virus posed to already marginalized immigrant communities.


The colour and colour rendering characteristics of natural daylight are considered together with the requirements for artificial daylight sources for critical colour matching purposes. The development of artificial daylight units utilising tubular fluorescent electric discharge lamps is shown to follow two main lines, namely, (a) a combination of fluorescent powders in either cold or hot cathode fluorescent lamps, and (b) a combination of radiation from fluorescent lamps and groups of incandescent tungsten filament lamps. Practical tubular fluorescent daylight colour matching units using cold cathode tubes are in use in industry for critical colour matching purposes, whilst experimental hot cathode lamps have been used in some prolonged field tests. An alternative method being investigated is to combine blue fluorescent lamps with incandescent tungsten filament lamps. This provides a closer approximation to black body spectral distribution than at present possible with fluorescent lamps alone, provided care is taken to ensure adequate mixing of the light, and adjustment is made for the differential life behaviour of the component lamps. The outstanding advantage of artificial daylight units incorporating tubular fluorescent lamps is their high efficiency (of the order of 30 lm/w.) which enables a very much higher illumination to be obtained over large working areas than has previously been practicable with filtered tungsten light or light from daylight units incorporating CO2 tubes.


Inclusive education (IE) and the special education services related to it are relatively new in Oman. Efforts to manage special/inclusive education face many challenges due to a number of culturally rooted factors. Further, empirical research on IE in Oman is scarce and there is a need to advance IE discourse based on empirically validated perspectives. This article examines how IE is managed in schools from the perspective of school leaders in order to develop a framework for action. The author conducted a preliminary qualitative inquiry into how IE is understood and managed in Key stage 1 schools in Oman. The inquiry was based on a focus group interview with a cohort of 25 school leaders who were completing a two year bachelor in educational administration, an endorsement-like programme at Sultan Qaboos University. Findings showed a number of challenges and tensions between theory and practice, highlighted by school leaders. These challenges and tensions were analysed in order to map out strengths and difficulties. A three level prism shaped framework for action was developed based on the analysis. The framework for action could potentially serve to guide policy- and decision-makers, researchers, practitioners, and is advocated to develop a model of best practice for the successful implementation and management of IE in Oman. [ABSTRACT FROM AUTHOR]


• Most acute respiratory infections (ARIs) in developed countries are viral in aetiology, uncomplicated and self-limiting. • Human metapneumovirus is a leading cause of ARIs in early childhood. • Respiratory viral infections are associated with most asthma exacerbations, particularly in children; rhinoviruses are the most commonly implicated virus. • The use of antibiotics in treating ARIs should only be considered in the presence of bacterial sequelae. • Although most children with ARIs can be managed in the community setting, some may be better referred to hospital. • Prevention strategies for ARIs include avoidance of environmental tobacco smoke exposure and immunisation against pneumococcal disease, invasive Haemophilus influenzae type b infection and, in some children, influenza.


In this paper, we present a new statistical model for Maximum Likelihood Classification (MLC) algorithm to improve the image segmentation/classification performance. MLC has been widely used in many classification applications. For supervised MLC, the parameters of the statistical model are obtained from the training dataset at the learning step. However, in the previous studies, the feature values of different classes are assumed to have similar distributions for different subjects. This is not true in many real world situations. The considerable differences across subjects have not obtained much attention before. To conquer this difficulty, we model the mean of feature values of each subject and the feature values as two groups of dependent random variables. This is made possible by using a bivariate Gaussian mixture model to fit the image data of different subjects. In this way, class membership depends on both the feature values and another random variable that captures subject-specific information. We apply our method to simulated image data and our experimental results show that the proposed model could improve the classical supervised MLC segmentation results when there are considerable differences across subjects.


The study aimed to identify the extent of the application of total quality management requirements from the viewpoint of teachers at the university of batna in Algeria, and to identify differences in attitudes resulting in a number of demographic changes, and thus develop a questionnaire distributed to a targeted sample of teachers, has been analyzing data using statistical analysis package (SPSS) and based on appropriate statistical indicators and tests. We have concluded that the application of total quality management requirements at the university of batna as members of the Teachers is a medium was also a substantial differences in attitudes of teachers, so they must work continuously on the development of the climate that fosters positive direction and senior management commitment to the participatory processes and continuous improvement.


Preparation and publication of this volume is made possible by funds appropriated by the State of Alaska for Coal Research.


OF THESIS INITIAL MICROSEISMIC RECORDINGS AT THE ONSET OF UNCONVENTIONAL HYDROCARBON DEVELOPMENT IN THE ROME TROUGH, EASTERN KENTUCKY The Cambrian Rogersville Shale is a part of a hydrocarbon system in the Rome Trough of eastern Kentucky and West Virginia that can only be produced unconventionally. In Kentucky, the Rogersville Shale ranges in depth from ~1,800 to ~3,700 m below the surface with the crystalline basement ~1,000 m lower than the formation's base. Baseline Rome Trough microseismicity data were collected, focusing on wastewater injection wells and recently completed and planned unconventional hydrocarbon test wells in the Rogersville Shale, using thirteen broadband seismic stations installed between June, 2015 and June, 2016 and existing University of Kentucky and central and eastern United States network stations. In addition, the network's minimum detection threshold, the magnitude at which the theoretical signal exceeds the noise by a factor of 3 between 1 and 20 Hz for at least 4 stations, was estimated for the project area. Thirty-eight local and regional events were located and magnitudes were calculated for each event. No events were proximal to operating disposal or hydrocarbon test wells, nor did any occur in the eastern Kentucky's Rome Trough. The minimum detection threshold varies between 0.4 and 0.7 Mw from 0000-1100 UTC and 0.6 to 0.9 Mw from 1100-2300 UTC.


In this paper, the delay phase multiplication algorithm is introduced, which is very suitable to detect direct sequence and frequency hopping hybrid spread spectrum signal, detection principle of this kind signal is also given simultaneously. In order to improve detection performance, circular correlation and adapti ve filtering algorithms are introduced. The improved algorithm has been successfully used to detect direct sequence and frequency hopping hybrid spread spectrum signal, the results show that the detection algorithm can not only detect direct sequence and frequency hopping hybrid spread spectrum signal with lower SNR, but at the same time achieve the code rate.


received from Dr. Kenneth E. Rowe. Cf. his presentation at Drew University in May 1988, "Celebrating Aldersgate: Historical Reflections" (unpublished). The incorrect assumption that the centennial of Aldersgate was celebrated in 1838 has sporadically appeared. It surfaced in editorial comments on the bicentennial of Aldersgate in 1938 (cf. London Quarterly and Holburn Review 163 [1938]: 253). The error was quickly pointed out (cf. "Wesley Day, 1938" Proceedings of the Wesley Historical Society 21 [1937–38]: 109–10). Unfortunately, this did not keep it from reappearing in editorials on the 225th anniversary (cf. Together 7.1 [1963]: 3) and reflections on the recent 250th anniversary (cf. John Lawson, The Conversion of the Wesleys [Derbys, England: Moorley's Bookshop, 1987], 20). It has even found its way into the recently completed History of the Methodist Church in Great Britain (London, Epworth, 1983) 3:43ff. Cf. John W. Drakeford, "How Growing Old Looks From Within: A Study of John Wesley's Perception of the Aging Process as Revealed in His Journal's 'Birthday Reflections'," Journal of Religion and Aging 1.2 (1984): 39–51. For Charles' mention of this practice, see: The Journal of Charles Wesley, M.A. (Kansas City, MO: Beacon Hill, 1980) 1:98–99. By contrast, no such mention is present in John's Journal or letters. Indeed, on the 50th anniversary (24 May 1788) his only Journal entry is a complaint about the poor quality of a preaching house that had just been built (The Journal of the Rev. John Wesley, A.M., ed. Nehemiah Curnock [London: Epworth, 1909–16], 7:391–92). There are no references to Aldersgate in extant letters written around this anniversary either.


ABSTRACT The diffusion and the recycling of electric and electronic equipment waste (WEEE) are an important issue for industrialised countries. During treatment operations of this equipment, legacy and emerging halogenated flame retardant can be released in the environment, causing great concern for their toxicity. For this purpose, a method to simultaneously determine polybrominated biphenyl ethers, hexabromocyclododecane, 10 emerging brominated flame retardants and in parallel-polychlorinated biphenyls was optimised and applied to particulate matter samples collected within a WEEE facility. In this paper, starting from a previously published method, we drastically simplified the sample preparation, reducing the overall completion time, solvent consumption, costs and achieving adequate selectivity and sensitivity for all the target compounds. The multi–analyte method was evaluated in terms of reproducibility, linearity, recovery, limits of detection, limit of quantification, and matrix effect and compared to the previous method. Quantitative analyses were carried out by gas chromatography-mass spectrometry in negative chemical ionisation, using matrix-matched calibration curves. The reliability and robustness of the method were demonstrated through the analysis of certified and reference compounds in Standard Reference Material 2585. The most abundant compounds in particulate matter samples, collected in an electric and electronic equipment waste treatment plant, were BDE 47 (3.9 ng m−3), CB 138 (2.7 ng m−3), and 1,2-bis(2,4,6-tribromophenoxy) ethane (4.2 ng m−3).


In this paper, effect of free surface fluctuation on dynamic response of offshore structures is studied. A single degree of freedom structure is subjected to a long-crested sinusoidal wave in water of arbitrary depth. Wave force is computed according to the Morison equation and wave induced fluid particle velocity and acceleration are modified to account for the effects of free surface fluctuation. The equation of motion is solved by an approximate analytical method in closed form. Results indicate that free surface fluctuation causes higher harmonic responses, produces bias in response, and its effects become important as water depth decreases.


ABSTRACT

In the study, the efficacy of 1-Methylcyclopropene (1-MCP) on the quality of apples cv. "Granny Smith" was examined. Fruits were stored for 120 and 180 days at 0 ± 0.5C and 90 ± 5% relative humidity (RH) under normal (NA) and controlled atmosphere (CA), and samples taken at 120 and 180 days of storage were kept at 20 ± 2C and 60 ± 5% RH for 7 days. Weight loss was higher in fruits stored under NA. The lowest respiration rates were in CA while the highest rates were found in NA-stored fruits without pretreated. 1-MCP + CA reduced the internal ethylene concentration from 10.63 µL/L to 0.60 µL. The incidence and severity of superficial scald was 68.10 and 77.00% in fruits stored in NA. 1-MCP consistently suppressed the expression of superficial scald. 1-MCP maintained the quality fruit kept in CA and NA environments to a higher degree than nontreated apples over a 180-day storage period. The results indicated that cv. "Granny Smith" could be stored successfully under 1-MCP + CA conditions and that 1-MCP + NA may be a viable alternative to CA for optimal eating quality.

PRACTICAL APPLICATIONS

1-Methylcyclopropene (1-MCP) is an effective inhibitor of ethylene action and it binds irreversibly to ethylene receptors. 1-MCP delays the onset of the climacteric ripening of fruits. Recently research has been conducted on the effects of 1-MCP on postharvest behavior of fruits and vegetables with the objective of reducing physiological disorders and quality losses to prolong their commercial life. The use of 1-MCP is easy. It is important that the fruit treated with 1-MCP reach a good sensory quality at the commercial level. Superficial scald of apples is a physiological disorder, which following long-term storage has the potential to destroy the market value and utility of millions of tons of fresh apples annually. The present work evaluated a prestorage conditioning treatment to protect against this physiological disorder. Results will allow the long storage of apple cv. "Granny Smith," benefiting growers, exporters, shippers and distributors of this horticultural product.


Sidaguri (S. rhombifolia L) is one of the most important species of medicinal part in Indonesia as anti-inflammation. To clarify this, we investigated the anti-inflammatory effect of the root of S. rhombifolia on rat periapical lesion model. The incisivus teeth were drilled to expose the dental pulp to the oral cavity and apical lesions were induced with LPS isolated from Porphyromonas gingivalis. Pour plate method was used to determine the bacterial CFU of gingival crevicular fluid (GCF) and C-reactive protein (CRP) serum was examined by enzyme-linked immunosorbent assay. The results showed that the root of S. rhombifolia could not reduce the total bacteria of GCF; however, it could reduce the level of CRP compared to negative control (p<0.05). In conclusion, S. rhombifolia has anti-inflammatory potency on rat periapical lesion.


Metal-organic frameworks (MOFs) materials have been widely used in environmental protection due to the unique characteristics such as high surface area, adjustable pore size and abundant functionalization. Recently, various methods have been applied to prepare continuous MOF catalytic membranes with active catalytic sites and uniform apertures to realize the effective separation and catalysis at the same time. This paper briefly introduces and compares the preparation methods of MOF catalytic membrane and analyses catalytic site on the related membranes. The applications of MOF catalytic membrane in environmental management are summarized and the expectations about future development way are made as well.


Standards of care change over time as new technologies are developed. It is of essential importance for physicians to keep their knowledge updated, and guidelines should assist by providing appropriate updates. The Clinical Practice Guidelines for Bladder Cancer by the Japanese Urological Association (JUA) were first published in 2009 and revised in 2015. We have experienced drastic changes in the management of bladder cancer since then, leading to the further revision of the guidelines in 2019. In the present article, Matsumoto et al. highlighted the main changes included in the latest update of the guidelines. Novel technologies might substantially improve the clinical practice of bladder cancer. The major revisions in the updated JUA guidelines included the recommendation of photodynamic diagnosis (PDD) for non-muscle-invasive bladder cancer (NMIBC), which has been recently covered by the public health insurance in Japan. PDD enables more precise visualization, particularly of small/flat lesions, in comparison with examination under white light. A large body of evidence has shown that PDD-assisted transurethral resection of bladder tumors decreased NMIBC recurrence by improving cancer detection. Previous studies also suggested that the risk stratification of NMIBC, which is widely utilized to predict recurrence/progression of bladder cancer in clinical practice, would be shifted based on the improved cancer detection by PDD. Further evidence will be required to define the optimal care for NMIBC patients in the "new standard" era. Another recent milestone in the management of bladder cancer in Japan is the health insurance coverage of robotassisted radical cystectomy (RARC), leading to the moderate recommendation of RARC, as well as laparoscopic radical cystectomy, in the updated JUA guidelines. This is based on the results of the RAZOR trial, published in 2018. Here, the surgical and oncological outcomes were compared between patients who underwent RARC and open radical cystectomy, which proved the non-inferiority of RARC. RARC is now increasingly carried out, which might benefit patients by minimizing surgical morbidity and improving patient recovery. Finally, but importantly, the KEYNOTE-045 trial, reported in 2017, has dramatically changed the treatment paradigm for advanced/metastatic bladder cancer. The updated JUA guidelines strongly recommended pembrolizumab for patients with advanced/metastatic cancer who are resistant to platinum-based chemotherapy. Further clinical trials are being carried out to investigate the impact of pembrolizumab in other settings; for example, first-line treatment with/without platinum-based chemotherapy, neoadjuvant/adjuvant therapy or combination with chemoradiotherapy for bladder preservation. These might explore further improvements in the management of bladder cancer and create new standards in the future.


On the commercial available server, the great workloads on CPU generally limit the performance of Input/Output (I/O) or delay the response time. A Network-Attached Storage Device (NASD) is developed to meet the scalability requirement of mass multimedia storage. The evaluating experiments in this paper indicate that the bottleneck of data transmission is not the capability of CPU, but the network and reading/recording speed of physical storage devices. To improve the performance of multimedia storage system, a scheme of NASD-based multi-port storage area network is presented. In the new system composed of one manager and several NASDs, the manager only assigns the task of data processing to the NASDs. The NASDs can dynamically generate the virtual files and sent them to clients directly. Act as a virtual server, the storage system can provide the multi-port service for the different clients and different requirements.


This research, bibliographical, aims to investigate difficulties and possibilities in the use of teaching technologies in Mathematics Education. Using the most diverse technological tools has long been an urgent need recognized by every education professional who is in line with the latest educational trends. Despite this urgent need, it is essential that the use of such resources enables education to achieve clear and precise objectives. Using technological tools solely to break with traditional education will not achieve the expected results of an education professional, so it is fundamental to research and experiment with the most diverse technological tools so that one can use the most appropriate tool for every moment and area of knowledge.


Marketing innovation is essential for small industries to transform products into profit and therefore, understanding its nature and determinants is of utmost importance. This study aimed at understanding marketing innovation and its determinants in the 60 small food industries in the rural areas of Tehran province, Iran. Using a census sampling method, 111 managers of these firms were interviewed. Results showed that the firms' performance in marketing innovation is generally weak and a higher level of radical innovation in marketing is perceived compared to the incremental innovation. Also, a cause and effect relationship exists between both "product and organizational innovations" and "marketing innovation". Furthermore, while "incremental marketing innovation" was negatively influenced by formal R&D unit, product diversification, and the manager's years of experience, "radical marketing innovation" was affected by the capacity of production, product diversification, and managers' age and education. The study concluded that in order to boost marketing innovation, innovation should be made also in products and organization. Besides, in order to facilitate the process of marketing innovation, practical and up-dated trainings for managers, encouraging incremental innovation in marketing, product diversification, and improving R&D activities in the studied firms should be regarded.


We take for granted the ability to smile, kiss, or close our eyes at night, all of which can be affected by facial paralysis. This condition may strike anyone at any time, regardless of age or gender. The project aims to develop a pair of glasses that discreetly provides real-time feedback to the wearer about their facial muscle function, helping them practice their rehabilitative exercises regularly and correctly, thereby speeding recovery of normal, symmetric facial expressions. The glasses will contain all the required EMG sensors in a compact form factor, they will provide sensor data to a mobile application installed on a mobile phone or tablet. The mobile application will provide daily exercises and feedback to allow the patients to monitor their own progress through the rehabilitation process and will also pass on valuable information to therapists via a website. Therapists will monitor the progress of their patients and adjust exercise routines as required. They will also provide feedback through in application messaging and feedback tools while providing in depth analysis tools to spot potential problems such as synkinesis.


Many native species of plants and animals in the Great Basin have a restricted geographic distribution that reflects the region's biogeographic history. Conservation of these species has become increasingly challenging in the face of changing environmental conditions and land management practices. This paper provides an overview of major stressors contributing to species' rarity and vulnerability and discusses associated management challenges and research needs.


In dielectric science, the electrical breakdown strength of a polymeric material significantly decreases with elevated temperatures, which restricts the development of advanced electrical and electronic applications toward miniaturization. In the present study, to clarify the temperature-dependent DC breakdown mechanisms of epoxy resin (EP)/TiO2 nanocomposites, the effects of nanoparticle incorporation and temperature on charge transport and molecular chain dynamics were studied. The results indicate that space charge accumulation and electric field distortion are reduced by nanoparticle incorporation to enhance the deep trap level, while space charge accumulation, electric field distortion, and molecular displacement are all accelerated as temperature increases. To further investigate the influence of carrier traps and molecular chain dynamics on temperature-dependent breakdown, a DC breakdown simulation model that involves bipolar charge transport, molecular chain dynamics, and breakdown criterion equations is established. The calculated breakdown strengths of EP/TiO2 nanocomposites show great accordance with the experimental results, which indicates that temperature-dependent DC breakdown mechanisms are dominated by the synergetic effects of carrier traps and segment chain dynamics. Through the analysis of the breakdown model, a transition of the dominant mechanism (from segment chain to backbone dynamics) near the glass-transition temperature for DC breakdown of EP/TiO2 nanocomposites is discovered.


The prediction of the behavior of actual structures is required for a structural design engineer. The structural models used in undergraduate classrooms have major drawbacks and are often special-purpose models used once per course. This paper identifies requirements for a suitable general-purpose model, describes a proven solution in kit form, and appraises its ability and versatility in illustrating fundamental structural behaviour. Students' appreciation of structural behavior is more rapid and positive, as the novel structural model kit permits them to both manipulate and observe.


The electronic policing construction is a close connection between police system creation and computer's networks technological creation. It is a systematic project concerning the police management modernization and the whole reform aspect of police system. Implementing electronic policing construction, taking the advantage of computer's network and informational technology to improve the police organizing agency, reorganizing work flow and management of different levels of police agency and different police categories will produce an impressive effect on strengthening the police functions in managing public security, changing way and style of work, gradually enhancing work quality and efficiency, establishing the police administrative management system of high-efficiency work, coordinated operation and regular behavior. Electronic policing construction is the motive force to push the historical transformation of police work forward.


The United States is in the midst of reevaluating its attitudes toward the smoking of tobacco. Incontrovertible evidence exists of smoking's widespread and direct negative effects on health. Increasingly, the effects of passive smoking have been documented (1). There has been a trend to restrict or eliminate smoking in both private and government sectors. General hospitals have begun to acknowledge this trend and are becoming more active in health promotion. Many have stopped the sale of cigarettes, have established nonsmoking aeas, and offer programs to help people stop smoking. Descriptions of some clinical programs are available (2), and guidelines for administration of no-smoking units have been presented (3).


Low-density lipoprotein cholesterol (LDL-C) is one of the most important modifiable cardiovascular risk factors. 1 In 2019, European guidelines lowered the recommended target LDL-C from <1.8mmol/L (70mg/dL) to <1.4mmol/L (55mg/dL) for secondary prevention in coronary artery disease. 2 Despite well-intended recommendations and strong evidence, the previous LDL-C target of <1.8mmol/L (70mg/dL) had only been achieved in 21% in regis-tries. 3,4 In Germany, the reported proportion was even lower with <_15% of patients achieving the target following an acute coronary syndrome. 5,6 This was potentially influenced by the fact that only simvastatin and pravastatin were recommended for out-patient use until 2017. Prescription of more potent statins such as atorvastatin and rosuvas-tatin or of ezetimibe implied the risk of financial repercussions for the prescribing


The article publishes previously unknown documents about L. A. Popugaeva from the personal archive of Professor D. P. Grigoriev, stored in the Commission on the History of the Russian Mineralogical Society: her letter from Nyurba dated August 5, 1956, a letter from VSEGEI with a request for guidance of a graduate student L. A. Popugaeva, a letter from CNILKS with a request for consultation signed by L. A. Popugaeva herself, as well as agendas for meetings of the Mineralogical Society and dissertations on the diamond problem. All documents are original, attributed and chronologically correlated with previously published documents. They are very valuable for the history of mineralogy as actual evidence of distant events. First of all, the documents mark the main stages of the life and scientific activity of an outstanding geologist, the discoverer of indigenous diamonds in Yakutia, L. A. Popugaeva. Secondly, they show her activity in the last professional field — the study of gemstone raw materials of the North-West Russia, mainly the Kola Peninsula. The article is dedicated to the date of the untimely death of L. A. Popugaeva.


Mozart's Starling by Lyanda Lynn Haupt. 2017. Little, Brown, New York, NY, USA. 277 pp., 20 text figures. $27.00 (hardcover). ISBN 978-0-316-37089-9. This is a nontechnical book written for lay readers about a musical genius, Wolfgang Amadeus Mozart, and a species of bird, the European Starling (Sturnus vulgaris). The author is a skilled writer who has written other books that feature birds, each with a focus on bird behavior (e.g., Crow Planet). There are two interweaving narratives in the book, one dealing with Mozart, who had a pet starling, and the other focused on the vocalizations and learning abilities of European Starlings and on their ecology, particularly their impacts on native bird species. Both narratives are skillfully interwoven, and the book is both entertaining and informative. Mozart discovered a starling for sale in a Vienna store. The bird could sing a version of his Piano Concerto no. 17 in G major. He was so captivated by the bird and its apparent good taste in music that he purchased it, naming it Star. It resided in his home and was always a favorite of the composer. When it eventually died, he held an elaborate funeral for it, far more elaborate than the one for his illustrious father, Leopold. Star is the ''hook'' that inspired Haupt to research Mozart, Star, and starlings and to formulate the book. Haupt is nothing if not thorough. She did the usual author's due diligence of traveling to Vienna and learning as much as she could about the composer, including tracking down where he was eventually buried in a common grave, a custom at the time. Her writing suggests a deep personal connection with Mozart (something shared by other music lovers), as well as with his starling (something unique to Haupt). But she did more. Haupt wanted to learn why starlings make captivating pets, so she adopted a newly hatched starling and raised it, naming it Carmen. Haupt firmly believed that she could not really understand Mozart's connection with Star unless she, herself, came to intimately know a starling. Mission accomplished. Much of the book focuses on Carmen's personality as a bird, her extensive interactions with Haupt, as well as a general treatment of starling vocalizations and behavior. Haupt did a thorough job of researching noteworthy scientific publications that range throughout the biology of the European Starling, including its ability to accomplish recursive grammar and the dynamics of starling murmuration flights. She makes a strong case for the intelligence of the species in general, using the extant literature as well as personal accounts of the behavior of Carmen. She also extensively interviewed some of the researchers to better grasp the research and its significance. Mozart wrote a highly strange piece of polytonal music, a divertimento for two horns and a string quartet titled Ein musikalischer Spass, or A Musical Joke. For most of us, the piece is very difficult if not painful to listen to, odd and


A highly general and centralized reasoning framework which combines first-order-logic with Markov networks proposed to recognize both simple and complex activities. The generality and systematicity of the reasoning framework is characterized by a newly defined set of spatio-temporal and spatial semantic free low level event predicates(LLEs). With the new low level event predicates any human activity represented by trajectories can be described without domain knowledge thus can be applied across domains. High-level events (HLEs) of interest across different domains can be described by encoding the newly defined HLEs and temporal logic (Allen's interval logic) in a first-order-logic presentation. The main contribution is the proposed reasoning framework represented by a new set of semantics free LLEs which can be utilized across different domains. The human action Kinect dataset from Microsoft Research(MSR) is used to evaluate the proposed gesture representation and recognition framework. The capacity of performing across different domains is validated on both MSR dataset and one synthetic interation dataset.


The adsorption and subsequent dissociation of O2 on Pt(111) was studied by variable temperature scanning tunneling microscopy in the temperature range of 40 to 215 K. Tight clustering of bridge site molecules is observed on terraces between 40 and 70 K, indicating a highly mobile precursor to chemisorption. Coexistence of bridge and fcc hollow site molecules in fractal-shaped islands is observed after dosing between 70 and 95 K. Dissociation of these species was induced by uv radiation, inelastic tunneling electrons, and heating. In all three cases, two O atoms are found within two lattice constants of the original molecule and one to three lattice constants apart.


This paper undertakes the study of multidimensional finite impulse response (FIR) filterbanks. One way to design a filterbank is to factorize its polyphase matrices in terms of elementary building blocks that are fully parameterized. Factorization of one-dimensional (1-D) paraunitary (PU) filterbanks has been successfully accomplished, but its generalization to the multidimensional case has been an open problem. In this paper, a complete factorization for multichannel, two-dimensional (2-D), FIR PU filterbanks is presented. This factorization is based on considering a two-variable FIR PU matrix as a polynomial in one variable whose coefficients are matrices with entries from the ring of polynomials in the other variable. This representation allows the polyphase matrix to be treated as a one-variable matrix polynomial. To perform the factorization, the definition of paraunitariness is generalized to the ring of polynomials. In addition, a new degree-one building block in the ring setting is defined. This results in a building block that generates all two-variable FIR PU matrices. A similar approach is taken for PU matrices with higher dimensions. However, only a first-level factorization is always possible in such cases. Further factorization depends on the structure of the factors obtained in the first level.


Peptide nucleic acid(PNA)is a DNA mimic,and it is biologically stable.PNA has been shown to hybridize in a sequence-specific manner and with high affinity to complementary sequences of single-stranded DNA or RNA molecules to form duplexes and triplexes of very high thermal stability.They are subjected to the base pairing rules of Watson-Crick and Hoogsteen,while they are resistant to digestion and degradation by nucleases and proteases.PNA-based PNA probe and PCR clamping technologies are now increasingly used in cancer and aging research and the diagnosis of chromosomal anomalies,bacterial and DNA point mutation.The PNA-assisted aminoacylation of tRNA with non-natural amino acids has been achieved and the artificial protein has also been translated.As an antisense agent,PNA was used in the inhibition of gene expression and proteinic translation in bacteria and virus with encouraging preliminary results.The PNA-Based RNA-triggered drug-releasing system is exquisite and the system is a promising drug of targeted therapy.


The operation of helicopters from small naval vessels like frigate present a demanding challenge for pilots. This paper studies the effect of active flow control system located along the sides of the hangar edges on the unsteady aerodynamic loads of a scaled rotor model operating along a stern approach. The flow field above the helideck is experimentally measured using stereo particle image velocimetry. These data are compared to ship airwake computations to assess the flow prediction capabilities. The ship airwake in headwind and G20 conditions without and with blowing are implemented into the Airbus Helicopters HOST simulation code based on the one-way coupling approach. The output data are equilibrium monitoring curves of the four commands states. The deviations induced by blowing are in the order of 1% to 25% and it allows at bringing the commands back to the uncontrolled airwake case.


We will discuss in this article a fractal-like structure made from a flat piece of paper. What will motivate most people to want to make the structure is that it is pretty. In fact, the exercise has two rather obvious uses. First, greeting card companies may want to use the idea to manufacture interesting 3-dimensional cards which fit conveniently into envelopes; and, second, teachers may wish to teach students how to make it (and this process will also involve teaching them some beautiful mathematics). The structure itself is a model for a stage in a self-similarity process leading to a fractal. Building the model involves scoring a flat piece of paper in a prescribed manner, cutting along some of the score lines, and then folding some lines as 'mountain' folds and others as 'valley' folds.


Pressure ulcers (PUs) have been documented for centuries yet remain a health and patient safety challenge worldwide. PU risk assessment including a skin assessment focused on those anatomical locations most prone to PU development is considered to be an important first step in evidence-based PU prevention. Nonblanchable erythema (NBE), category 1 PU according to recent PU classifications, is widely accepted as a key clinical sign that pressure damage may have occurred. The work by Shi et al. published in this issue of the BJD strongly supports the close association between NBE and the high risk of PU development. However, assessing NBE in clinical practice has limitations:


This study suggests the development of forecasting model for local cable TV advertisement. In order to verify the expected effect of the suggestion, using the causal loop map of System Dynamics, the factors affecting the prospects of cable TV commercial market were divided into 5 groups. Then targeting 97 people involved in the cable TV commercial market in Busan, Ulsan, and Gyeongnam, a survey was conducted on their perception of the current status of local advertisement market and future prospect. order to qualitative and quantitative factors, and using Multi-attribute Decision Making method, all the factors were normalized and weighting factors were deduced. The result of simulating the prospects of cable TV commercial market using Weighted Moving Average, both qualitative and quantitative factors showed downward turn in the market prospect for the following 10 years. study has its significance in that it used scientific method and simulation for verification.


Diabetes Mellitus is a chronic metabolic disorder which adversely affects the body's ability to manufacture and/or
utilise insulin, a hormone required for the transformation of
glucose into energy. Diabetes affects ten million people in the
US, and its prevalence is increasing by 6% p.a. Long term
diabetic complications arise from the greatly accelerated degeneration of blood vessels in many organs, which can lead to blindness, kidney failure, heart attack, stroke, gangrene and problems of the nervous system.


Objective To investigate the effect of percutaneous nephrolithotomy( PCNL) clinical efficacy and safety of the treatment of patients with urinary calculi. Methods A retrospective analysis was performed on the 2011 February to 2012 December in our hospital clinical data of 116 cases of upper urinary tract calculi in patients with percutaneous nephrolithotomy treatment. Results 116 cases were successful removal of the stones,the stone clearance rate was 93. 1%. The average operation time was 89 minutes,the amount of bleeding during an average of about 80mL,the average length of time 8. 5 days,no serious complications. Conclusion Percutaneous nephrolithotomy( PCNL) for the treatment of upper urinary tract calculi has high curative effect,less injury,high safety,rapid recovery and shorter hospitalization time etc,can be used as the main treatment method,it is worth in clinical use.


The utility model relates to a storage battery shifting device. Nowadays, a fork truck is required to be lifted out from the fork truck frame by a crane to be replaced when the storage energy is used up, which is very inconvenient. An inlet and an outlet of the storage battery are arranged at the side face of the fork truck frame in the utility model, the inlet and the outlet are corresponding to the position of storage battery containers. Rollers are arranged on the bottom plate of the fork truck frame, and the storage battery containers are arranged movably on the rollers. When the storage battery is replaced in the utility model, the storage battery containers are only required to be pulled out and pushed in through the inlet and the outlet of the storage battery, the storage battery can be easily replaced without the large-size crane, and the replacement is very convenient.


Deng xiaoping developed Mao zedong's theory of the united front in the new historic period.He innovated the theory in the following aspects:the character and countermeasure,the status and function,the tasks and the organic form and institution of the theory of the united front.


Owing to the rapid growth of extensive information flow, almost all the money-makers across the globe be governed by business intelligence to yield profit boosting decisions. Right from stock-market to small independent startups, investors employ several data mining techniques to estimate the payback of their investments. However, it has been noticed that an economic and proficient infrastructure, in case of retail marts can yield noteworthy profits. This paper comes up with a framework which uses machine learning techniques to suggest constant refinements in the architectural set-up of the retail specific to garment sector based upon the data of the customers. The following sections comprise of a comparative study of a few retail industries' recommender systems and also a novel approach to achieve more efficient recommendations for widespread sales promotion.


In late 1985, Congress mandated that the U.S. stockpile of lethal unitary chemical agents and munitions be destroyed by the Department of the Army in a manner that provides maximum protection to the environment, the general public and personnel involved in the disposal program (Public Law 99-1, Section 1412, Title 14, Part b). These unitary munitions were last manufactured in the late 1960`s. The stockpiled inventory is estimated to approximate 25,000-30,000 tons, an includes organophosphate ({open_quotes}nerves{close_quotes}) agents such as VX [O-ethylester of S-(diisopropyl aminoethyl) methyl phosphonothiolate, C{sub 11}H{sub 26}NO{sub 2}PS] and vesicant ({open_quotes}blister{close_quotes}) agents such as Hd [sulfur mustard; bis (2-chloroethyl sulfide), C{sub 4}H{sub 8}Cl{sub 2}S]. The method of agent destruction selected by the Department of the Army is combined high-temperature and high-residence time incineration at secured military installations where munitions are currently stockpiled. This program supports the research program to address: the biomonitoring of nerve agent exposure; agent detection limits in foods and milk; and permeation of agents through porous construction materials.


As an effort to help contain the COVID-19 pandemic, large numbers of SARS-CoV-2 genomes have been sequenced from all continents. More than one million viral sequences are publicly available as of April 2021. Many studies estimate viral genealogies from these sequences, as these can provide valuable information about the spread of the pandemic across time and space. Additionally such data are a rich source of information about molecular evolutionary processes including natural selection, for example allowing the identification and investigating the spread of new variants conferring transmissibility and immunity evasion advantages to the virus. To validate new methods and to verify results resulting from these vast datasets, one needs an efficient simulator able to simulate the pandemic to approximate world-scale scenarios and generate viral genealogies of millions of samples. Here, we introduce a new fast simulator VGsim which addresses this problem. The simulation process is split into two phases. During the forward run the algorithm generates a chain of events reflecting the dynamics of the pandemic using an hierarchical version of the Gillespie algorithm. During the backward run a coalescent-like approach generates a tree genealogy of samples conditioning on the events chain generated during the forward run. Our software can model complex population structure, epistasis and immunity escape. The code is freely available at https://github.com/Genomics-HSE/VGsim.


New Schiff-base polyesters were prepared from a dihydroxy monomer (E)-1-(5-(4-hydroxy-3-chlorobenzylidene)thiocarbamoylaminonaphthyl)-3-(4-hydroxy-3-chlorobenzylidene)thiourea. The processable pyridine or thiophene-based poly(azomethine–ester)s (PAEs) possess high molar mass of 111 × 103–127 × 103 g mol−1. The 10% weight loss (521–527°C) and glass transition temperature (287–291°C) depicted high thermal stability. Polyaniline (PAN) doped with dodecylbenzenesulfonic acid (PAN/DBSA), prepared by in situ doping polymerization, was blended in solution/melt with PAEs. Field emission scanning electron microscopy of melt blended PAEs/PAN/DBSA showed nanolevel homogeneity of microstructure accountable for superior electrical conductivity (1.9–2.8 S cm−1). The miscible nanoblends also exhibited high heat stability (T 10; 500–507°C) and mechanical strength (45.51–48.17 MPa) relative to reported azomethine/PAN-based structures.


The aim of this study is to describe different root-end filling materials according to the literature and to compare their antibacterial activity, sealing ability, biocompatibility and microleakageThe purpose of a root-end filling is to establish a seal between the root canal space and the periapical tissues. A number of materials have been suggested for use as root end fillings, including gutta-percha, amalgam, Cavit, intermediate restorative material (IRM), super EBA, glass ionomers, composite resins, carboxylate cements, zinc phosphate cements, zinc oxide-eugenol cements and mineral trioxide aggregate (MTA).


This article gives a detailed analysis on the 10 deficiencies of due process of death penalty in China: the principle of "presuming to be innocent" is, in fact, not being obeyed; the suspects and the defendant face many difficulties in defending themselves, and their human rights are not guaranteed sufficiently in the proceeding; the criminal awaiting execution lacks rights to appeal for abatement or pardon; judicial organs lack qualifications;there is no rule to prevent a case from being tried twice;requirements of evidence for death penalty are too low and the voting procedure is not suitable.


Wireless sensor networks (WSNs) over the years have emerged as the enabling underlining infrastructure for new wireless technology trends such as Internet-of Things (IoT) and Fog Computing. Its application has spread across diverse fields such as agriculture, military, healthcare and home automation. Despite its promising attributes, it is characterized by its extremely limited resources such as battery energy and memory. Additionally, its deployment in hostile and unattended areas make it vulnerable to security attacks. One of such attacks is the denial of service (DoS) jamming attack that is perpetrated by malicious nodes emitting radio frequency signals to disrupt and interfere with the normal functions of the sensor nodes in the network. This eventually causes a denial of service in the network. Different routing protocols have been proposed over the years to guarantee reliable communication and maintain the network lifetime and functionality for a reasonable duration, notwithstanding DoS jamming attack. Therefore, in this work, we evaluate the effect of a constant jamming DoS attack on two key reactive routing protocols in WSN, ad hoc on-demand distance vector (AODV) and dynamic source routing (DSR). Metrics such as packet sending ratio (PSR), packet loss (PL) and transmitted packets are used to measure the impact of constant jamming DoS attack in the network. Simulation results using network simulation 2 (NS2) and trace graph show that, irrespective of the adopted reactive routing protocol, the impact of the jamming attack is the same.


The relevance of this article is justified by the consideration of some features of writing at the initial stage of teaching a foreign / English language. The goal of this work is the functional aspects of the content of speech activities, where written and the level of formation of the communicative competence of students, which provide more efficient use of writing as a means and opportunity for improving the graphic design of the text, as well as creating a base for spelling learning, is an important and key factor written training that determines the level of language proficiency. The result of studying the question of this article is the formulation of the problem, which is associated with the process of organizing training in writing, and is based on methodological recommendations for creating a base of reproductive and productive skills in foreign language writing.


This paper addresses the problem of giving a formal metric to estimate uncertainty at the moment of starting a distributed scientific calculation on clients working over mobile ad-hoc networks (MANETs). Measuring the uncertainty related to the successful completion of a distributed computation on the aforementioned network infrastructure is based on the Dempster-Shafer Theory of Evidence (DST). Shannon Entropy will be the formal mechanism by which the conflict in the scenarios proposed in this paper will be estimated. This paper will begin with a description of the procedure by which connectivity probability is to be obtained and will continue by presenting the mobility model most appropriate for the performed simulations. Finally, simulations will be performed to calculate the Shannon Entropy, after which the corresponding conclusions will be presented.


Buckwheat flower buds or juice liquid raw juice obtained, then the juice was prepared by the rich buckwheat medicinal ingredients, suitable for drinking pink juice drinks. Buckwheat flower buds juice or juice was obtained, the juice was frozen after thawing, so under normal temperature and lactic acid fermentation yeast isolated pink supernatant obtained buckwheat or buckwheat flower buds juice juice. After the juice was frozen, thawed, frozen in liquid juice utilizing the natural thawing initiator lactic yeast fermentation, separation pink supernatant.


The invention relates to an electronic device (10) comprising a board (12) having a first contact point (14) and a second contact point (15), and a control electronics (13) on the board. The control electronics has a first terminal which is electrically connected to the first contact point and a second terminal which is electrically connected to the second contact point (15). The electronic device (10) further comprises an electrically conductive mesh (19). Here, the board (12) from the network (19) is at least partially enclosed. The network (19) is in this case connected by means of at least one conductive elastomer (17) with the first contact point (14) and the second contact point (15) of the board (12). The invention further relates to the use of a conductive elastomer (17) in an arrangement for making an electrical contact as well as a method for detecting unauthorized, mechanical attempts to access an electronic device (10).


ATRX is a Rad54 translocase homolog implicated in regulating the epigenetic environment of heterochromatin, mitosis, and gene transcription. Myelin is a specialized membrane encompassing axons of neurons, allowing for efficient propagation of action potentials. CNS myelin arises via oligodendrocyte precursor cell (OPC) differentiation into myelinating oligodendrocytes (OLs), which then extend and wrap axons. Myelination is a tightly regulated process, however the mechanisms involved have yet to fully manifest. Here, we report that ATRX loss results in hypomyelination due to a defect in OPC differentiation and OL maturation, as ATRX loss did not affect OPC production, proliferation, or cholesterol biosynthesis. Additionally, myelin sheath formation was unaffected when ATRX was lost specifically from OLs, suggesting a non cell-autonomous role of ATRX in myelination. Clarifying the role of ATRX in myelination presents a novel mechanism that regulates myelin sheath formation, and findings from this study will benefit future treatments of myelin disorders, including ATR-X.


Gingival recessions are one of the most common aesthetic and functional periodontal problems, but also one of the most difficult in terms of etiology and treatment. Various surgical treatments for this condition have been described in the literature. Root closure for gingival recession using PerioDerm is one such method that has shown promising results. The purpose of this case series reports is to demonstrate the benefits of PerioDerm™ Acellular Dermis (DENTSPLY Tulsa Dental Specialties; Tulsa, Oklahoma) in reducing recession and adding connective tissue during periodontal-restorative complex treatment.The use of PerioDerm has shown positive results and has shown itself as a viable option for closing roots during a recession.


From the First Whigs to the True Whigs "But she is a Whig," an academic woman of high distinction once said to me of Caroline Robbins, whom this essay was first written to honor. The description may have been culturally rather than historiographically apt; a case can be made for regarding Professor Robbins not indeed as a gravedigger, but certainly as a deconstructor of the Whig monolith – if, that is, it should not be thought "Whiggish" to maintain that there ever was one. Her major work, The Eighteenth-Century Commonwealthman , appeared in 1959, and its function was to reveal to us the existence of a persistent tradition of Whig dissent, in which a succession of Old Whigs, True Whigs, and Honest Whigs – collectively known to us as "Commonwealthmen" – kept up a criticism of the principles and practices of the regime known to us as "the Whig supremacy," originating before its foundations in the Revolution of 1688 and audible well after the revolutions of 1776 and 1789. There was in fact a profound schism in Whig political culture, and we have been working out its implications ever since. Let us review the historiographical chronology. Almost thirty years earlier, Herbert Butterfield had taught us to view with suspicion what he called "the Whig interpretation of history," and by 1959 we had begun studying its origin as itself a historical phenomenon.


This study presents a shear strength prediction model for concrete beams reinforced with GFRP bars. An empirical equation is developed using multiple regression analysis from the experimental results of 16 RC beams with GFRP bars. The proposed equation involved the parameters that affected the shear strength of beams such as compressive concrete strength, shear span ratio, longitudinal reinforcement ratio and modulus elasticity of the reinforcement. The accuracy of the proposed equation was verified by predicting the available experimental data from the literature. Furthermore, the predictions of shear capacities were compared with the current shear design code of ACI 440.1R-06. As a result, the ACI 440 provides very conservative prediction, while a better prediction is obtained from the shear strength prediction model in the present study.


There is growing debate, both social and academic, about the possibility of levying an annual net wealth tax. Until a few years ago, such a proposal appeared difficult to both implement and control, but recent technological innovations, which could greatly facilitate the periodic valuation of wealth, combined with improvements in international tax information sharing could make a "modern wealth tax" possible. Nonetheless, a number of challenges regarding its design still need to be addressed. Taking advantage of the Spanish experience—the only EU country to levy a wealth tax—we undertake a quantitative analysis of various key legal elements of the current tax (exemptions and the common income and wealth tax ceiling) by means of a tax simulator we have developed; we also analyze its redistributive power. Our results show that the family business exemption and the common ceilings are highly regressive. We also assess the effectiveness of alternative reforms with more comprehensive tax bases (JEL codes: H24, H23, and D31).


A healthy 33-year-old man suffered an injury to his right leg in a mine explosion in 1969. The sciatic nerve was divided and the hamstring muscles were injured in the extensive blast injury. A faciotomy was performed through the tensor fascia lata (TFL). The resulting skin defect was skin grafted soon after the initial operation, but the fascia lata was not repaired. Although the patient gradually became ambulatory, he had a peroneal motor palsy; sensation was regained to a protective level after 2 years. The TFL defect was then repaired because walking was painful. The repair dehisced approximately 3 months later. The defect was then extended for the length of the thigh, and additional margins of TFL were removed to relieve the pain of muscle herniation. Enlarging the defect increased the amount of muscle herniating through it. The distal portion of the defect then closed spontaneously, creating a smaller defect. The hernia was again enlarged by removing an extra margin of the fascia. One year following the most recent surgical resection of the fascial edges, the external defect measured 27 x 12 cm (Fig. 1). The patient experienced intense pain from the bulging vastus lateralis, which continued to protrude through the TFL defect despite physical therapy.


Conformance checking is an important process mining task; it aims to detect inconsistencies between the model of a process and its corresponding execution log. This paper proposes an approach in which it is given a declarative description, represented by a set of temporal logic properties, for the process model; the process discovered from the log is described by means of a process algebra, and conformance checking is performed through the model checking of the discovered process against the properties. To discover the process we consider additional information contained in the log and associated with the single events. Moreover, since discovered processes tend, in general, to be very large and complex, we look for a reduced process containing only the parts relevant for the properties satisfaction. In this way we reduce both the space needed for the discovered process and the time complexity for the properties verification.


3 RIASSUNTO 5 INTRODUCTION 9 Endocrine Hypertension 9 Primary Aldosteronism 10 Familial Forms of PA 11 Sporadic Cases of PA 13 Expression and Detection of CYP11B2 and CYP11B1 in the Adrenal Cortex 15 Synthesis of Monoclonal Antibodies against CYP11B2 and CYP11B1 17 Histology of the Normal Human Adrenal Gland 18 Adrenocortical Steroidogenic Zonation with Aging 20 Adrenal Tissue Adjacent to the APA 21 Histology of the APA 22 Somatic Mutations in the Potassium Channel Kir3.4 25 Clinical Implications of the Antibodies against CYP11B1 and CYP11B2 27 GENERAL AIM 29 SPECIFIC AIMS 29 MATERIAL AND METHODS 31 Patients 31 APA – DNA Preparation 32 APA – cDNA Preparation and Genotyping 32 High Resolution Melting (HRM) Analysis 32 Immunohistochemistry 33 Immunofluorescence 34 Identification of Patterns Based on IHC using CYP11B2/CYP11B1 Antibodies 34


New ZrO2/Al2O3/ZrO2 (ZAZ) dielectric film was theoretically designed and successfully demonstrated to be applicable to 45nm DRAM devices. ZAZ dielectric film is a combined structure from tetragonal ZrO2 and amorphous Al 2O3. Thus prepared ZAZ TFT capacitors showed very small Tox.eq value of 6.3Aring and low leakage current less than 1fA/cell. It was also confirmed that ZAZ TFT capacitor was thermally robust during backend full thermal process by applying it to the final DRAM product in mass production


The article reveals some problems of applying the provisions of certain laws of Ukraine regarding
ownership transparency of broadcasters, such as an imperfect terminological apparatus of the Law of
Ukraine "On Television and Radio Broadcasting"; discrepancy between its mechanisms and purpose of
legal regulation; insufficient resources of regulatory and control bodies in checking the reliability of
information on the ownership structure of broadcasters. The legislation on the transparency of media
ownership has been designed to introduce additional guarantees of free speech and to create transparent
conditions for the licensing of broadcasting as a means to guarantee distribution of objective and unbiased
information free of any pressure and censorship. Proceeding from the research, the author concludes that
the current legislation of Ukraine on the transparency of media ownership is at the stage of initial formation.
Thus, the most difficult practical issue is the application of the Law on affiliates and related persons of
the subject of information activities. The above definition in the law does not distinguish between them.
Affiliates, in the author's opinion, should be considered as type-related persons. Such ambiguity in the
legislation deviates from the principle of legal certainty. Another problem that has arisen in the practical
application of the Law is that the information to be disclosed is classified information about legal entities
in which the subject information activities owners and their family members are managers or owners of
substantial participation. After all, in terms of goals, disclosure of legal entities operating in other markets,
has no meaning.
Therefore it is essential in the nearest future to focus on identifying the maximum number of practical
problems in their application in order to avoid mechanical transfer of imperfect norms of the Law of Ukraine
"On audiovisual services". This is currently being developed to meet the requirements of the Association
Agreement between Ukraine and the EU and is to become the main core law in audiovisual services.


Sponsored by the CINEMar Program at the University of New Hampshire, Agreement No. 03-
671 to NOAA Grant Nos. NA06RP0454 and NA16RP1718.


With the increasing population and the development in flood prone areas,floods have become major society disrupting disasters.It is realized that flood defending is not the best way to survive from the flooding.In addition to structural measures,the non-structural measures have been introduced to control flooding in recent years.ASAR data and DEM file are used to extract water depth data using GIS tools.Three common interpolation algorithms(IDW,Kriging and Topo to Raster) have been used to interpolate points with elevation into water surfaces.However,the results from these methods are not satisfactory and therefore a new interpolation algorithm ADDM(Average distance dependent method) has been developed to solve this problem.Comparisons between the results of ADDM and the three common methods are carried out in the research.The results show that the new developed ADDM method is better than the other three methods,whatever on the water depth distribution or on the continuity of the water surfaces.Hence the new method can be used as a more reliable procedure to interpolate the points in case are elevations were extracted from a coarse DEM.All the four algorithms have been tested on a case study using real-life data.The flood hazard map of Dongting Lake is generated based on the water depth results developed by ADDM and flood frequency.It is proved that ASAR images and 90 m×90 m DEM are capable of developing flood hazard map.


Amphiphilic block copolymers based on azido-functional polystyrene (PVBA) and hydrophilic poly(ethylene oxide) (PEO) have been synthesized by nitroxide mediated polymerization and used to prepare aqueous spherical micelles. These micelles consisting of a PEO corona and a PVBA core were stabilized by cores cross-linking under UV irradiation without addition of photoreagent. The efficiency of the core cross-linking was estimated in term of the conversion of azide groups to dibenzyldiazene junctions with liberation of gaseous nitrogen molecules. The micellar structures were studied by dynamic light scattering (DLS) and atomic force microscopy (AFM). Differential scanning calorimetry (DSC) was used to characterize the thermal behavior of freeze-dried micelles. Attachment of PEO block to a rigid core modified considerably the thermal behavior of PEO. We observed a decrease of about 15 °C for the crystallization temperature and 50% for the degree of crystallinity of cross-linked micelles submitted to 45 min UV ...


Modeling the meso-scale behavior of a material allows one to answer many problems in an inductive reasoning approach. By simulating the behavior of the sample, researchers can correct the overall behavior of the material. The purpose of this article was to gather the main information linking the issue of tomographic imaging to the modeling of damage mechanisms. This paper addresses the topic of meso-scale modeling of cementitious materials. The authors have mapped the interconnectedness of the issues of cementitious materials and X-ray computed tomography (µCT) according to the Web of Science database. The main interconnecting threads are indicated. The authors focused on the use of µCT. The theoretical basis for conducting tomographic measurements is presented. Reference was made to the basics of physics and mathematics in X-ray projection and data reconstruction. Tools and analyses for data processing are indicated. The benefits of in situ µCT are indicated with reference to the practical application of the method. In addition, the main developments of recent years in the most widely used computational methods for meso-scale models are presented.


Endometrial stromal sarcoma is rare, comprising 10% of the uterine mesenchymal tumors, and one-half of women affected are postmenopausal. They are classified into endometrial stromal nodule and endometrial stromal sarcoma that are low-grade malignant tumors of uterus. They are indolent tumors with local recurrences and distant metastasis occurring even 20 years after initial diagnosis. Most endometrial stromal sarcomas stained positively for CD10, estrogen receptor, progesterone receptor, and bcl-2, mostly in a diffuse pattern. The present case is of a 45 years female patient presented with abdominal pain and irregular menstruation, white discharge, bleeding per vagina for last six months. She had undergone tubectomy 6 years ago. Per abdominal examination revealed distended abdomen with aversion of umbilicus. There was no evidence of free fluid in the abdomen. Ultrasonography was carried out which revealed a bulky uterus with solid lesion in the myometrium showing heterogenous echo texture. Total vaginal hysterectomy was carried out and the specimen was sent to department of pathology. Grossly, the uterus was large, globular and firm. The cut-section shows bulky tumour, greywhite-to-yellow nodular mass in colour, with infiltrating margins, measuring about 5.0 X 5.0 X 4.0 cms. The endometrium is distorted by the tumour. Microscopically, the uterus showed tumour composed of small-to-medium sized cells, roundto-oval & spindle shaped cells with large hyperchromatic nuclei and occasional mitosis, small amount of cytoplasm. These tumour cells are showing infiltrating margins, focal necrosis, hemorrhage, local invasion and lymphatic emboli. Immunohistochemistry showed CD 10, Estrogen, and Progesterone receptors positive. It was confirmed that as endometrial stromal sarcomas which is presented here for its rarity. Key-words: Uterus, endometrial stromal sarcoma, low grade


Lipomas are mesenchymal tumors of the adipose tissue described in various sites including the oral cavity but rarely the tongue. Based on the clinical appearance, color, consistency, invasion, oral lipomas, may be simple, angiolipoma, intra/inter muscular (infiltrating), lipoblastoma, spindle cell, pleomorphic, myxoid and atypical lipomas but 80% of these are classical lipomas and may cause functional and cosmetic disabilities. A case of intramuscular lipoma of tongue is reported for the rarity of site and number and to review the clinical, diagnostic and histopathologic findings.


ejd.2010.1213 Auteur(s) : Sultan Al-KHENAIZAN email@example.com, Bassim AL-BEROUTI Division of Dermatology, Department of Medicine, King Fahad National Guard Hospital, P.O. Box 22490, Riyadh 11426, Kingdom of Saudi Arabia An 18-year-old, Saudi, male, single, university student, presented with an asymptomatic skin eruption for 4 weeks. The eruption appeared 3 weeks following chemotherapy for stage IIA Burkitt's lymphoma, which included, among others, bleomycin in a total cumulative dose [...]