OBJECTIVE To preliminarily discuss the effect of softening liver and lowering fat capsule on containing atherosclerosis when the capsule was used singly and together with Simvastatin,through observing the influence of the capsule on dyslipidemia,changing of high-sensitivity C-reactive protein(CPR) and atherosclerosis.METHODS The condition of rats was compared before and after administration by the methods of group molding,blood fat and CPR detection,liver function detection,light microscope examination,and so on.RESULTS Serum TC,TG,and LDL of administration group was significantly lower than control group;serum CRP of the group which used softening liver and lowering fat capsule together with Simvastatin slightly was lower than the group used capsule singly,without significantly difference;liver function index of rats using softening liver and lowering fat capsule singly had no significantly difference with normal group while index in the group of using Simvastatin singly ascended;in the prevention group of softening liver and lowering fat capsule the endotheliocyte partly detached,with relative integrity,slightly lipid deposition,and rare elastic plate fracture;in the Simvastatin group the aortic wall structure was similar with the group of capsule,but the group in which the two used together was better than the singly used group.CONCLUSION Both using softening liver and lowering fat capsule singly and together with Simvastatin can effectively contain the process of atherosclerosis.


In this note, we wrote the preface for the first volume of the International Journal of Reproducing Kernels (The Roman Science Publications and Distributions (RSPD): https://romanpub.com/ijrk.php). Incidentally, this year is one century since the origin of reproducing kernels at Berlin. For some detailed information of the origin and some global situation of the theory of reproducing kernels with the content of the first volume are introduced. 1 Origin of Reproducing Kernels 100 years ago in summer 1922 two young mathematicians defended their Ph.D. theses at the university in Berlin, Gábor Szegö and Stefan Bergmann (later: Bergman). Szegö at that time had published a couple of papers already and defended his second thesis (habilitation thesis), [3], while Bergman, an assistant with Richard von Mises, [4], p. 472, had just started his publications in this particular year. Both have started the theory of Reproducing Kernels. It might just have been a case of coincidence that this has happened at the same time and


Law of Criminal Procedure in 1996 confirmed attorne y's right of participating lawsuit and meeting with criminal suspect in the stage of detection,but it is not general that the attorney meets with criminal suspect in the stage of detection.Meeting with the difficulty of meeting,we should obtain from following aspects: establishing silence right system;The oral confession which is achieved by way of preventing the attorney meeting can not be regarded as verdict basis;awarding the court the authority of investigating and deciding about whether the detection is valid.


The article analyses how to train the students' occupation ability in the teaching of architecture design practice by a practice course and brings forward that it is necessary for the polytechnic academy to make occupation atmosphere and carry out the teaching mode of process controlling.


This note concerns the study of the incremental entropy of a quantum black hole, based on Operator Algebra methods. Our results are based on the results presented in the references [6, 11, 12, 13].


Objective To investigate the influence of different Mg2+ concentration on biofilm formation by mucoid Pseudomonas aeruginosa.Method Multifunction fluorometer was used to measure fluorescence of PA at the bottom of 96-well plate.The EPS of PA was stained with FITC-ConA and detected by fluorescence microscope.The biofilm was stained with SYTO9/PI,monitored by Confocal Laser Scanning Microscope(CLSM).Quantification of the effect was calculated by Image Structor Analyzer(ISA) sofeware.Result Two days group: after intervention with 1 mmol/L Mg2+,the fluorescence intensity was increased from 1845.67±45.39 to 2254.78±42.45,t=-9.96,P0.05;0.1 mmol/L Mg2+ could also increase the fluorescence intensity;Other time groups showed approximate tendency as two days group;the EPS in biofilm was significantly increased after intervention with Mg2+,which was visualized by fluorescence microscope,based on the FITC-ConA stain.The live bacteria in the biofilm increase and colony close-up after administration of Mg2+,when observed by CLSM,based on the SYTO9/PI stain.The quantitative data from ISA software showed that after administration of 1 mmol/L Mg2+,the depth of 6 day biofilm increase from(25.80±1.16)μm to(34.87±1.59)μm(t=-13.85,P0.05).Areal porosity decrease from 0.96±0.05 to 0.90±0.04(t= 2.48,P0.05),average diffusion distance increase from 1.54±0.15 to 1.92±0.16(t=5.23,P0.05),and textual entropy increase from 3.64±0.57 to 4.70±1.09(t=-2.6,P0.05).The 3 day biofilm showed the same tendency.Conclusion Magnesium can increase the initial attachment of PA and alter the subsequent biofilm formation and structure.


The testing of material in order to determine its conformity to a microbiological standard involves two main processes; selection of the samples of material to be tested, and the testing of this material. For the procedure to be reliable, the sampled material must be representative of the whole and the test must give a reliable result. The errors arising from the sampling stage are indicated in this paper, and sampling schemes which have been recommended for this purpose are discussed. The chief test methods (colony and total counts, dilution methods, presence/absence tests, and chemical methods) are then discussed, both from the point of view of their underlying statistical reliability and the assessment of operator errors. Finally it is concluded that the initial sampling stage is the most critical part of any test procedure and where representative samples are difficult to obtain, the enforcement of a code of practice in manufacture is preferable to attempts to control quality by subsequent testing.


The present invention discloses an in-cell touch color filter substrate and manufacturing method. Wherein the in-cell touch color filter substrate comprising: a substrate, the substrate comprising a plurality of display regions and the plurality of the non-display region surrounding the display region; sequentially formed on the first metal layer on the substrate, a first organic film layer, a second metal layer and a second organic film layer, said second metal layer comprises a plurality of conductive pads disposed in a non-display area; wherein, in a first organic film layer on the non-display area is formed within the a plurality of through-hole or through groove, the conductive pad is electrically connected to said first through said through hole or through groove with the metal layer, and the conductive pad is exposed to the outside of the second organic film layer. According to the present invention in-cell touch color filter substrate, the sealant can effectively reduce the coating times, which can greatly improve the production efficiency.


We describe three families with X‐linked mental retardation, two with a deletion of a single amino acid and one with a missense mutation in the proximal domain of the RSK2(RPS6KA3) (ribosomal protein S6 kinase, 90 kDa, polypeptide 3) protein similar to mutations found in Coffin–Lowry syndrome (CLS). In two families, the clinical diagnosis had been nonsyndromic X‐linked mental retardation. In the third family, although CLS had been suspected, the clinical features were atypical and the degree of intellectual disability much less than expected. These families show that strict reliance on classical clinical criteria for mutation testing may result in a missed diagnosis. A less targeted screening approach to mutation testing is advocated.


This paper will describe the actual operating performance of the Tevatron, operating as a collider, and will indicate the planned upgrades which will enhance, the physics results coming from the experiments being performed at Fermilab.


Cell lines and patient-derived xenografts are essential to cancer research, however, the results derived from such models often lack clinical translatability, as these models do not fully recapitulate the complex cancer biology. It is critically important to better understand the systematic differences between cell lines, xenografts and clinical tumors, and to be able to identify pre-clinical models that sufficiently resemble the biological characteristics of clinical tumors across different cancers. On another side, direct comparison of transcriptional profiles from pre-clinical models and clinical tumors is infeasible due to the mixture of technical artifacts and inherent biological signals. To address these challenges, we developed MOBER, Multi-Origin Batch Effect Remover method, to simultaneously extract biologically meaningful embeddings and remove batch effects from transcriptomic datasets of different origin. MOBER consists of two neural networks: conditional variational autoencoder and source discriminator neural network that is trained in adversarial fashion. We applied MOBER on transcriptional profiles from 932 cancer cell lines, 434 patient-derived tumor xenografts and 11'159 clinical tumors and identified pre-clinical models with greatest transcriptional fidelity to clinical tumors, and models that are transcriptionally unrepresentative of their respective clinical tumors. MOBER can conserve the biological signals from the original datasets, while generating embeddings that do not encode confounder information. In addition, it allows for transformation of transcriptional profiles of pre-clinical models to resemble the ones of clinical tumors, and therefore can be used to improve the clinical translation of insights gained from pre-clinical models. As a batch effect removal method, MOBER can be applied widely to transcriptomics datasets of different origin, allowing for integration of multiple datasets simultaneously.


This paper investigates the localization of a moving source in position and velocity, by observing the emitted frequency from the source that is subject to the Doppler shift effect at a number of stationary sensors. Previous attempts rely on exhaustive grid search or numerical polynomial optimization to obtain a solution. We shall propose a constrained optimization to formulate the localization problem, which enables the problem to be solved efficiently using the linear optimization method to reach a closed-form solution or the semi-definite relaxation technique to achieve a noise resilient estimate. The algorithms are developed for the single-time and multiple-time observations. The presence of errors in the source frequency and the sensor positions are considered. The non-cooperative scenario where the source frequency is completely not known is also addressed. Analysis validates the proposed closed-form solution in reaching the Cramer-Rao Lower Bound accuracy under Gaussian noise over the small error region. Simulations support the performance of the proposed solutions.


A cost-effective WDM cipher system based on signal masking by quantum (shot) noise is proposed. Four 12-Gbaud QPSK channels are simultaneously converted to Y-00 ciphers with 218 phase levels by a common phase randomization component.


Cloud computing plays a significant role in business organisations by offering many benefits and opportunities. However, the adoption of cloud computing involves some trepidation. The adoption of cloud computing in developing countries is still in the early phase. The bank sector in Saudi Arabia aims to benefit from opportunities offered by the cloud computing technology; however, some banks continue to hesitate in the implementation of this technology. Therefore, this study aims to investigate factors that influence the attitude of the Saudi Arabian bank sector towards adopting cloud computing. A model that incorporates factors derived from the literature is developed in this study to determine whether specific factors positively or negatively affect the attitude of the Saudi bank sector towards adopting cloud computing. A quantitative method is used and data are collected from decision makers and IT staff members in the Saudi bank sector. Results showed that factors of security and privacy exert a significant negative effect whilst factors of benefits and competition pressure demonstrate a significant positive effect on the Saudi bank sector attitude towards adopting cloud computing. Thus, cloud computing providers must focus more on negative influential factors to reduce the apprehension of the bank sector in adopting the cloud computing technology. In addition, the bank sector must also consider factors that can drive the adoption of cloud computing as well as opportunities and losses if this technology is rejected.


Launched in Germany in about 2006, whole-body electromyostimulation (WB-EMS) is a young exercise technology. Due to its increasing popularity, time-efficiency, jointfriendliness and individualized application, WB-EMS has been increasingly been the subject of scientific research. Apart from the current Research Topics, the large variety of articles published during the last 2 years has considerably increased the evidence for positive effects on relevant health and performance related parameters. Notably, there is a clear tendency towards the scientific application of WB-EMS in the area of "health" that have been mirrored in the present Research Topic. Summarizing the published articles, at least six of seven contributions addressed health-related outcomes while one study Verch et al. can be considered as a methodological trial that determined the specific effect ofWBEMS combined with walking and Nordic Walking on oxygen consumption (VO2) in healthy adults. Although the authors reported significant net effects on average VO2 (≈10%) during the 10 min treadmill test, they doubt the clinical relevance of their results. In line with similar data of longitudinal studies (e.g. Mathes et al., 2017), this result questioned (once again) the concept of superimposed WB-EMS application during endurance exercise at least in non-athletic cohorts. In their meta-analysis Kemmler et al., on the other hand, provided strong evidence for a large effect of WB-EMS on muscle mass and strength parameters in non-athletic adult cohorts. However, although six of the twelve trials included obese participants, the authors OPEN ACCESS


Based on the direct shear tests of schist and shale at dry and water-saturated states, combed with the advantages and disadvantages of models for rock mass and structure surface, we proposed shear stress-displacement constitutive model of schistose rock mass. The model is in the form of piecewise exponential function and its advantages are as follows: Piecewise function can reasonably describe the nonlinear pre-peak shear hardening and post-peak shear softening characteristics; Regard peak strength, peak displacement and residual strength as critical points, so it can accurately describe the strength characteristics of the material; The fitting degree is high with direct shear tests both at dry and water-saturated states; Only one parameter value is needed to obtain by fitting experimental curves while others are convenient to determine. All of those are benefit to applications in engineering practice.


The increasing demand for mobility in our society poses various challenges to traffic engineering, computer science in general, and artificial intelligence in particular. Increasing the capacity of road networks is not always possible, thus a more efficient use of the available transportation infrastructure is required. Another issue is that many problems in traffic management and control are inherently decentralized and/or require adaptation to the traffic situation. Hence, there is a close relationship to multiagent reinforcement learning. However, using reinforcement learning poses the challenge that the state space is normally large and continuous, thus it is necessary to find appropriate schemes to deal with discretization of the state space. To address these issues, a multiagent system with agents learning independently via a learning algorithm was proposed, which is based on estimating Q-values from k-nearest neighbors. In the present paper, we extend this approach and include transfer of experiences among the agents, especially when an agent does not have a good set of k experiences. We deal with traffic signal control, running experiments on a traffic network in which we vary the traffic situation along time, and compare our approach to two baselines (one involving reinforcement learning and one based on fixed times). Our results show that the extended method pays off when an agent returns to an already experienced traffic situation.


The Equal Opportunities Commission (EOC) has begun an investigation into why most jobs currently have a gender imbalance within their workforce. The latest in a series of updates has been published by the Association of Educational Psychologists (AEP) on gender distribution amongst educational psychologists. This may therefore be an opportune time to look at issues of gender balance within the population of educational psychologists (EPs). Currently males are in a minority throughout the study and practice of psychology. The small and diminishing proportion of male EPs appears to be seldom discussed within the profession. This paper attempts to evaluate a range of possible explanations for the lack of male EPs. The process of gender stereotyping was offered as one theoretical framework which might help guide further investigations into this much overlooked area.


Objective: To investigate the expression of human papilloma virus in the sinonasal inverted papilloma and papillous squamous cell carcinoma,and to study the correlation of the expression of HPV with development and progression of the sinonasal inverted papilloma.Methods: HPV(wide-spectrum model)protein expression in 49 paraffin tissue specimen of sinonasal,including inverted papilloma,papillous squamous cell carcinoma and 11 paraffin tissue specimen of chronic inflammations(nasal polypus)were detected using immunohistochemical EnVision two step method.Results: HPV in the inverted papilloma and papillous squamous cell carcinoma was observed,the overall positive rate of HPV was 34.7%(17/49).Expression of HPV was not found in 11 chronic inflammations(nasal polypus).The positive rate of HPV was 38.2%(13/34)in the sinonasal inverted papilloma,26.7%(4/15)in the papillous squamous cell carcinoma.The correlation of the sinonasal inverted papilloma and the papillous squamous cell carcinoma was not statistically significant in the positive rate of HPV.The correlation of chronic inflammation(nasal polypus)and inverted papilloma,papillous squamous cell carcinoma was statistically significant in the positive rate of HPV(P0.05).Conclusion: HPV infection is likely to have close correlation with the development of sinonasal inverted papilloma and papillous squamous cell carcinoma.Nevertheless,the correlation needs further research between HPV infection and carcinogenesis of sinonasal inverted papilloma.


Background : Xerosis is a result of decreased water content of the stratum corneum, which leads to abnormal desquamation of corneocytes. Treatment with using moisturizer has a function to keep the water content of the skin between 10% until 30%. Most of the moisturizers use synthetic adhesives which based on literally it adduce side effect. There is extensive need to replace toxic synthetic agent from base using component of herbal to decrease the side effect of moisturizing. This research product examine the active component of Aloe vera and Tea tree oil in moisturizing formulation. Purpose : To know the effectiveness of Aloe vera extract and tea tree oil mixtures in formulating moisturizer for dry skin. Metodh :This research is experimental with one group pre test post test design which use 35 respondents. Respondents who had negative patch test, filled the questionnaire on pre test according to Visual Skin Score. Respondents used the research product on their foot twice a day for 21 days. Finally, respondents filled questionnaire on post test. Data was examined by Wilcoxon text with the standart of significance p < 0,05 Result : There are 26 respondents (74,3%) have increased their level of skin moisturizing, 9 respondents (25,7%) have not changed, and no one has decreased the level of the skin moisturizing. The result of Wilcoxon text is obtained p <0,05 Conclusion : Aloe vera extract and tea tree oil mixtures in formulating moisturizer is effective for dry skin.


Teaching History is a tough and challenging task for teachers because most students consider History as a boring subject. Many studies indicate that students are not interested in learning History. This paper is based on a quasi-experimental study conducted to investigate the effects of utilizing the concept map method in the teaching of History in secondary schools. The researchers investigated whether the use of concept maps in the teaching of History helped the subjects from the experimental group to answer history questions better than the control group. The researchers also investigated whether this method helped to enhance students' interest in the learning of History. The findings of this research indicated that the utilisation of the concept map method significantly improved students' achievement and interest in History. Findings of this study support the theory of meaningful learning and utilization of concept maps. Moreover, the findings have strong pedagogical implications on teaching of History. As such, the practical implications are that the Ministry of Education should train History teacher how to utilize concept maps in teaching of History.


To test the relevance of bony fusion of distal femoral and proximal tibial epiphysis by means of Magnetic Resonance Imaging (MRI), a cross-sectional study was performed to determine the reliability of 16 and 18 years of life. Methodology: We scanned 140 Indian (Bengali) subjects in the age bracket of 3 and 35 using 1.5 T MR-scanner utilising T1 turbo spin-echo sequence representing true bone anatomy, in the Indian Bengali population. Minimum, maximum, mean and standard deviation were defined. Bony fusion took place before the 18 year of life. Intraand interobserver agreements were determined by calculating the kappa coefficients. Bony fusion of distal femoral and proximal tibial epiphyses in 1.5 Tesla MRI is useful only to a certain extent in determining age 16 to 17 years of life in both sexes, but completion of 18 year of life cannot be solely determined by MRI from bony fusion of knee.


This article argues that globalisation, which has become an undisputed phenomenon in the post-Cold War era, is not new. Rather, it is an acceleration of the process of capital accumulation and exportation to the South, which has been in place since the seventeenth century. However, in the post-Cold War era this process changed qualitatively from its previous character with the emergence of new global institutions such as the World Trade Organisation (WTO) and regimes like the Uruguay Rounds Agreements (URA) which supervise and regulate trade among nations. The contemporary globalisation has spawned competition, which has ultimately worked to the disadvantage of Africa. Consequently, while other regions find niches in the increasingly competitive global market and thus getting integrated into the international economy, Africa's posture in the global economy is getting increasingly ambivalent. On the one hand, Africa's increasing marginalisation is reflected in its declining share of world trade, overseas development assistance (ODA), direct foreign investments (DFI), and the loss of its previous comparative advantage in the supply of raw materials. On the other hand, Africa's dependence on the global market and International Financial Institutions (IFIs) is growing. This uncertain position in the global economy has also produced adverse consequences such that while Africa's economies stagnate or decline under the weight of market liberalisation, the economies of East Asia, for example, grow. In general, globalisation created major challenges for Africa. These challenges include the erosion of the continent's tenuous sovereignty, which has been subverted by market forces and IFIs; the creation of salutary conditions for intra-state contestations and armed conflicts; impeding Africa's efforts at establishing a common market; and hastening environmental degradation on the continent. It is argued further that the very logic of globalisation vitiates the efforts of African states to adequately respond to these challenges.


AbstractThrough a good understanding of the Arabic language, it will be able to be equipped in understanding the Qur'an and Hadith. Understanding Arabic cannot be separated from studying nahwu shorof. But in learning it, of course there are certain methods that can help to make it easier to understand. Therefore, in this study the author will examine the implementation of the Manhaji method in learning nahwu shorof on the manhaji course. The research method used is a qualitative method that is descriptive analytical. The results of the study note that there is an implementation of learning nahwu shorof in Manhaji Course which is different from other methods. The most striking difference is that this method is more enjoyable in learning, overall, examples taken directly from the Qur'an, complete and general for all groups and various levels, focusing on tarjamah al-Qur'an, translating nahwiyah with the dhomir mentioned for the word berkhomir.Keywords: Arabic, Hajj method


Purpose: Our purpose is to develop and test a molecular probe that can detect the expression of neutropilin-1 receptor (NPR-1) in vivo using fluorescence imaging and photoacoustic spectroscopy. Introduction: NPR-1 is expressed on endothelial cells and some breast cancer cells, and binds to vascular endothelial growth factor VEGF165, a growth factor associated with pathological tumor angiogenesis. This receptor is coexpressed with VEGFR2 and shown to enhance the binding of VEGF165; therefore, it has the potential to be used as a marker of angiogenic activity and targeted for therapy. Material and Methods: A peptide specific to NPR-1 receptor was synthesized and conjugated to a NIR fluorochrome (IRDye800CW) and was intravenously injected into mice with breast tumors (MCF7VEGF). Probe kinetics was monitored in vivo via near infrared fluorescence (NIRF) within an optical imager for up to 72 hours within the tumor and compared to other organs (liver, muscle) for binding specificity. A multivariate fitting algorithm was used to spectrally deconvolve the IRDye800CW from endogenous hemoglobin signature (hemoglobin concentration and oxygen saturation). Results: Dynamics of the NIR fluorescence signal within the first hour after injection indicates specific binding compared to muscle, with an average tumor-to-muscle ration of 2.00 (+/- 0.27). Spectral analysis clearly indentified the presence of the NPR-1 probe. Based on calibration data, the average tumor concentration from both NIRF and PCT-S was measured to be ~200-300nM. Conclusion: These preliminary results show the capability of PCT to image an exogenous probe in vivo in addition to its hemoglobin state.


Parsonage–Turner syndrome is a rare and painful peripheral neuropathy that usually presents as brachial plexus neuritis and also has other nerve involvement.


Predictions of trends in the distribution of known diseases can be used to inform and drive public health action. Given the strong linkage between climate and influenza, we propose an in-depth study of the relationship between humdidty and other climate variables and influenza morbidity and mortality at various temporal and spatial scales. Although several studies indicate that relative humidity affects both influenza virus transmission and influenza virus survival, a new lab-based study suggests that it is absolute humidity that constrains both transmission efficiency of the influenza virus survival and its transmission. We test this assumption using a 20-year disease and humidity data for seven US cities. The ultimate goal of the study is to make it possible to use weather and climate predictions at or before the start of the influenza season to provide valuable prediction of the characteristics of the season. We further suggest that using the NASA Terrestrial Observation and Prediction System offers a unique and promising opportunity to apply data from NASA satellites and modeling frameworks to enable prediction of the severity and peak time of influenza based on climate indicators. Improving the predictability of influenza can result in the development of more cost effective and successful disease control strategies and enhance our understanding of how the disease might respond to potential climate changes.


. It is necessary to differentiate when considering the effectiveness of the organization's management system: the organizational structure of management as a formalized descriptive scheme for the distribution of tasks and responsibilities and the organizational management system as approaches, methods used in the relationship between the object and the subject of management. The article provides assessment tools in the case of considering the efficiency of the func-tioning of the managed system as a whole or its elements: comparison of the market value of the organization and the book value of its assets or equity; comparison of the amount of revenue, net profit, industry average profitability indicators and indicators of a particular organization; comparison of non-financial indicators, for example, market share, labor productivity, employee sat-isfaction, etc. It is shown that index and coefficient methods are used to assess the effectiveness of management in the narrow sense as the effectiveness of the actual management activity. The method for assessing the effectiveness of an organization's management system is proposed. The results of practical research on the proposed method are shown on the example of domestic and foreign industrial enterprises.


The first big breakthrough, by [Kirby-Siebenmann, 1969, 1969a, 1977], was an obstruction theory for the problem of triangulating a given topological manifold as a PL (= Piecewise-Linear) manifold. If BTop and BPL are the stable classifying spaces (as described in the lectures), they showed that the relative homotopy group πj(BTop, BPL) is cyclic of order two for j = 4, and zero otherwise. Given an n-dimensional topological manifold M, it follows that there is an obstruction o ∈ H(M; Z/2) to triangulating M as a PL-manifold. In dimensions n ≥ 5 this is the only obstruction. Given such a triangulation, there is a similar obstruction in H(M; Z/2) to its uniqueness up to a PL-isomorphism which is topologically isotopic to the identity. In particular, they proved the following.


Exposure to exercise and extreme environments, such as exertional heat stroke (EHS), can induce a long‐term epigenetic memory of stress that is stored as altered DNA‐methylation and/or histone posttranslational modifications. These changes can ultimately affect gene and protein expression as well as cellular function, which may lead to greater disease susceptibility. Previously, we have observed that a single bout of EHS can drastically alter the DNA methylome in monocytes lasting up to 30 days; however, whether these epigenetic changes are reflected in skeletal muscle has not been characterized.


The loyalty of Nyctimene robinsoni to its daytime roosting sites at the end of the dry season was assessed using radio tracking in Cape Tribulation, far north Queensland, Australia. N. robinsoni is a solitary roosting bat which specializes in figs. Bats were netted in front of a female fruiting Ficus congesta and glue-on transmitters were attached. Bats were then tracked to their daytime roosting sites and GPS coordinates were recorded. Night time positions were also monitored to gather information about how far from its roosting site each bat was foraging. A total of five bats were tagged although only two remained in range long enough to collect long term data. Of the two bats with long term transmitters one used a total of 7 different sites over 23 days. The second used 3 sites over 24 days. A study performed 20 years ago at the same location found N. robinsoni to be very faithful to their roosting sites although it varied from individual to individual (Spencer and Fleming 1989). This study found N. robinsoni not very loyal to a specific site but generally very loyal to a small section of the forest. Some reasons for this difference likely include a shift from a largely grassland study area to one generally covered with successional rainforest, creating more available roosting sites, and a generally wetter climate than in 1987, which encourages more trees to fruit.


The Inverted Pendulum is the benchmark system for control methods. Most linear controllers are not efficient under the situations of disturbances and other uncertainties. As high precision and robustness are required, a sliding mode controller is used in this work. Due to uncertainties, a model free based observer is used to estimate some states. The simulation and real experiment results demonstrate the robustness of the controller and the efficiency of a model free observer.


The present invention is directed to antibodies and fragments thereof having binding specificity for PCSK9. Another embodiment of the present invention, V The present invention also provides a complex of one or more functional or detectable moieties complexed with anti PCSK9 antibodies and their binding fragments are also contemplated. The present invention also contemplates a method of manufacturing the anti-PCSK9 antibodies and binding fragments thereof. Embodiments of the invention also diagnosis of diseases and disorders related to PCSK9, also relates to the use of anti-PCSK9 antibodies and binding fragments for evaluation and treatment. .BACKGROUND


During the past several decades the three-dimensional shapes of cells which are ;entially undifferentiated morphologically have been studied by a number of instigators. Many different organisms have been used. Some research has also en done on configurational changes, during cell division, in epidermal layers. lus far, however, no analysis has been made anywhere of the shape changes, step step, which take place during the course of cell division. Furthermore, no study latever, from this standpoint, has heretofore been carried out on cells deep within ,issue. In view of the increased emphasis, both morphological and physiological, iced upon terminal and lateral plant meristems, the internal cells, within the im apex, were chosen for this study of the progressive shape changes of dividing Is.


Summary A case of hypernatraemic dehydration due to diarrhoeal illness is described. The child, despite receiving oral rehydration therapy at home, was clinically dehydrated on admission to hospital. The plasma sodium concentration was 154 mmolll. In the next 21 hours following admission, a total of 3600 ml of oral rehydration solutions were administered orally. The child, following rehydration, with intravenous fluids, made a full recovery.


ABSTRACT The junction temperature of LED (light emitting diode) has a significant impact on its performance and lifetime. In this paper, a simplified model based on the finite element analysis is developed to simulate the temperature distribution of the 200 W LED module using software ANSYS. The model contains LED package, the heat pipe radiator, as well as TIM (thermal interface material) between the LED package and radiator. The temperature distribution of the simulation agrees with that of the experimental measurement. Thickness of TIM affects the heat dissipation significantly, the chips temperature and the maximum temperature difference of chips increases sharply with TIM thickness increasing. Substituting aluminum fins with copper fins cannot improve the heat dissipation performance of heat pipe radiator, and the air velocity of heat pipe radiator plays a key role in the heat dissipation. Thermal conductivity of package submount directly affects the chip temperature and the uniformity of temperature distribution of package submount.


Objective To explore the predictive value of qualitative microalbuminuria detection in screening for diabetic nephropathy among diabetic patients with different fasting blood glucose levels.Methods A total of 62 type 2 diabetes patients were divided into well control group,normal control group and poor control group according to their fasting blood glucose levels,and they all had qualitative test for microalbuminuria.Results Qualitative microalbuminuria detection revealed positive rate of the poor control group was 45.83%(11/24),significant different from the 11.76%(2/17)of the well control group and 28.57%(6/21)of the normal control group(P0.01),indicating the positive correlation between the qualitative test result and the fasting blood glucose level.And it was shown qualitative microalbuminuria detection was a necessary complementation to fasting blood glucose monitoring.Conclusion With advantages of simple operation,quick result,and cheap price,qualitative microalbuminuria detection with Micral-test strips(Roche Diagnostics)is suitable for diabetic nephropathy screening among patients with high risks in commutity hospital since it shows great significance for the early intervention and treatment of this disease.


PurposeMagnetohydrodynamic (MHD) nanoliquid are significant for thermal conductivity enhancement. The examination of heat transfer of crushing time-subordinate liquid flow past isometric surfaces has throughout the decades been a field of consideration for its wide scope of physical necessities: nourishment preparation, pressure, grease setup and hydrodynamic machines. Entropy generation in the squeezing flow of viscous nanomaterial is developed. MHD, Brownian motion and thermophoresis are considered. Porous space between the disks is taken. The analysis is carried out in the presence of radiation and viscous dissipation.Design/methodology/approachNonlinear systems are reduced to an ordinary one through similarity variables. The convergent solution is developed by employing the homotopy analysis technique (HAM).FindingsConvergent homotopic solutions are developed for the velocity, temperature and concentration. Entropy generation and Bejan number are explained. Skin friction and Nusselt number and Sherwood number are analyzed. For a higher approximation of porosity, parameter velocity is augmented. Temperature upsurges for larger thermophoresis and Brownian diffusion parameters. Concentration has an increasing effect on thermophoresis and Brownian diffusion parameters. For the rising value of the radiation parameter, both the Bejan number and entropy rate have increasing behaviors.Originality/valueNo such work is yet published in the literature.


In recent years, remote sensing and other applications have used hyperspectral image processing in a variety of ways. For more precise and in-depth information extraction, hyperspectral images offer a wealth of spectral information to recognize and discriminate spectrally identical materials. Numerous cutting-edge methods based on spectral and spatial data are available for hyperspectral image classification. Convolutional neural network (CNN), a subclass of artificial neural networks has gained popularity in a number of fields, including hyperspectral image classification. CNN is built to automatically and adaptively learn spatial hierarchies of data by backpropagation using a variety of building blocks, including convolution layers, pooling layers, and fully connected layers. In this paper, different CNN architectures such as IDCNN, 2D-CNN, 3D-CNN and 3D2D-CNN are evaluated to classify hyperspectral images. Experiments are performed on Indiana Pines and Pavia University images. Experimental results show that 3D2D-CNN gives highest classification accuracy.


ABSTRACT Family demography is the study of family structure. Family formations have resemblance in Asia and Africa, for instance most of the marriages practices in these two countries have been of the form of arranged marriages. The objective of this study is to investigate the family structure between sub-Sahara Africa and Asian continents. Secondary information (data) from different literature reviews was used. The information will be qualitative investigations done during different years by different countries. The causes of child marriage in Africa are due to poverty, tradition, protecting family honor and gender inequalities. In South Asian countries the highest number of nuclear household families is found in India. Policymakers, researchers and government and non-governmental organizations will get a better understanding of family issues within the households of those countries.


Abstract Introduction: Pulmonary arterial hypertension (PAH) is a complex disease with poor prognosis. Serum uric acid has been proposed as a potentially non-invasive and objective parameter for prognosis and response to therapy. Objectives: To investigate the potent relationship between serum uric acid levels and functional and echocardiographic parameters in children with PAH. Methods: Serum uric acid levels were measured in 34 children with PAH and were correlated with the functional class, 6-minute walk test, and echocardiographic parameters at baseline and at 12 months follow-up. Results: In pediatric PAH patients serum uric acid levels were higher compared with the control subjects (p = 0.001). In the high uric acid group serum uric acid levels were correlated with 6-minute walk test (p = 0.008), and with several echocardiographic parameters, such as pulmonary vascular resistance (p = 0.04), fractional area change (p = 0.05), left ventricle eccentricity index (p = 0.04), right atrial area (p = 0.03), right ventricle myocardial index (p = 0.01), and pericardial effusion (p = 0.001), markers of right ventricular overload and dysfunction. Conclusions: Serum uric acid levels are easy to collect and measure, and correlate with both functional and echocardiographic parameters that reflect right ventricular dysfunction.


Certain risks are very common to any application of a downhole control system during workover, while others will be field-specific or at least increased or decreased by the given well conditions. Workover anomalies may be caused by erosion, corrosion, mechanical errors, temperature effects on electronics, wear and tear on the dynamic seals or seizure of moving components. Obviously, the simpler the system and the fewer moving parts, the fewer components are available to fail. Procedures and supporting control software must be developed to ensure optimum system use. Blowouts are not very common today as most of blowout preventing systems serve the purpose. But, occasionally, these systems may fail due to either technical problems on the wellbore equipment or human error. Both reasons can cause an enormous damage on wellbore equipment, reservoir, surface facilities or even human loss. The right accidental risk assessment approach can reduce chances of repeating bad scenarios happened in the past.


10.21276/sajb.2017.5.9.4 Abstract: Campomelic dysplasia (CD; OMIM #114290) is an osteochondrodysplasia associated with skeletal malformations and sex reversal. It occurs due to de novo mutations in SOX9 gene in the 17q24 chromosome. It is associated with bent lower limbs, micrognathia, cleft palate, hypoplastic scapulae, congenital hip dislocation and a high rate of neonatal mortality. We evaluated 2 neonates diagnosed as CD on the basis of these findings. One of them was born to a diabetic mother, none of them showed sex reversal and only one survived the first year of life. Genetic counseling was given to the families of the patients.


While a good deal of research in simultaneous equation models has been conducted to examine the small sample properties of coefficient estimators there has not been a corresponding interest in the properties of estimators for the associated variances. In this paper we build on Kiviet and Phillips (2000) and explore the biases in variance estimators. This is done for the 2SLS and the MLIML estimators.The approximations to the bias are then used to develop less biased estimators whose properties are examined and compared in a number of simulation experiments. In addition, a bootstrap estimator is included which is found to perform especially well. The experiments also consider coverage probabilities/test sizes and test powers of the t-tests where it is shown that tests based on 2SLS are generally oversized while test sizes based on MLIML are closer to nominal levels. In both cases test statistics based on the corrected variance estimates generally have a higher power than standard procedures.


In this paper,the pels of original figure image is decomposed into n the same size data matrixes based on indeterminate equation of first degree.These n data matrixes are scrambled to n encrypt matrixes based on matrix scrambling.These n encrypt matrixes are fused into an encrypt matrixes based on image matrix fusion technique.Consequently,a method of encrypt original figure image is obtained.This paper gives an example to prove the security of the figure image encryption technique.


Classical artificial neural networks (ANN) and neurocomputing are reviewed for implementing a real time medical image diagnosis. An algorithm known as the self-reference matched filter that emulates the spatio-temporal integration ability of the human visual system might be utilized for multi-frame processing of medical imaging data. A Cauchy machine, implementing a fast simulated annealing schedule, can determine the degree of abnormality by the degree of orthogonality between the patient imagery and the class of features of healthy persons. An automatic inspection process based on multiple modality image sequences is simulated by incorporating the following new developments: (1) 1-D space-filling Peano curves to preserve the 2-D neighborhood pixels' relationship; (2) fast simulated Cauchy annealing for the global optimization of self-feature extraction; and (3) a mini-max energy function for the intra-inter cluster-segregation respectively useful for top-down ANN designs.© (1993) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.


By the idea of the inverse moment,we provide an approximate estimation for the parameter of the sample distribution under type-Ⅱ censoring when product life time follows linear failure rate model.By the Monte-Carlo simulation,when the sample capability is fixed,the precision is high with the number of the data is large,when the number of the data is small namely the number of the missing data is large,the error of the estimation for the parameter is biased big,the precision for the parameter estimation is successfully satisfied when the number of the missing data is not large.


It is shown that the numerical solution of electromagnetic scattering problems using moment methods can be carried out in a progressive manner by dividing the scattering surface into several small regions. The technique reduces the large matrix of the conventional moment method into several small matrices on the regions and enables one to solve easily the problem of scattering by very large objects. The accuracy of the method and the criteria for controlling computational errors are examined by its application to two-dimensional problems. Both parallel and perpendicular polarizations are assumed and the behaviour of the solutions for both smooth and singular field distributions on circular cylinders and prisms is studied. It is found that the surface distributions, such as induced currents, may be obtained more accurately by this method than the conventional moment method. The accuracy of the far fields, however, are generally of the same order for both methods. For convenience and brevity, the term PNM is used to refer to the method throughout this paper.


Horse dung contains considerable amounts of nitrogen which is partly lost during the storage period. Leaching of nitrogen from the dung can be prevented with constructions but also gaseous N-emissions occur. However, the emission rates are not reported in the literature. We measured in laboratory conditions nitrous oxide (N2O), nitric oxide (NO) and nitrous acid (HONO) emissions from fresh, one month old and one year old horse dung samples. NO and HONO emissions increased with the storage time of the dung. The mean emission rates of HONO and NO were from 36 to 280 ng N kg dw-1 h-1 and from 15 to 3500 ng N kg dw-1 h-1, respectively. N2O emissions were more variable showing also highest emissions (20.3 μg N kg dw-1 h-1) from the oldest samples. Thus, the longer storage of horse dung increases gaseous N losses which should be taken into account when planning an environmental friendly way to handle horse dung.


Purpose: The present study aims to validate the ayurvedic anthropometical parameter for assessment of proper growth & devlopment and also to identify any disease linkage. For proper bony growth adequate calcium supplement is necessary. Evaluation of role of an ayurvedic compound containing calcium preparation needed therefore included in the second phase of the study. In calcium deficiency Ayurvedic Managment "Suktyadi Yog" may be useful. It is a rich source of calcium and have deepaniya drugs. Deepaniya drugs is useful for absorption of calcium. Method: Validations of Ayurvedic Sharir pramana on the basis of modern concept (Parameters) in children and Peer review journals were searched to list content of "Suktyadi yog" with calcium supplementation activities, particularly acting in calcium deficient and healthy children. Result: Result of the study show Sharir praman of children found almost equal to as explained in ayurvedic texts. Out of all research Sukti bhasma, Godanti bhasma, yasad bhasma and Trikatu was found potent to reduce Calcium deficiency. It is very cost effective, easily available with highest calcium supplementation properties. Conclusion: Calcium deficiency is a major problem in children and "Suktyadi yog" is a best option to reduce it.


Abstract : This report summarizes the results of two investigations performed in support of the MX Full Scale Engineering Development program. The first investigation focused on alternative ways to present guidance system test data to enhance the effectiveness of preflight accuracy assurance procedures. The attributes of a desirable accuracy assurance system are discussed and the nature of the required structure and contents of such a system in the MX guidance context are defined. A review of the MX guidance production test structure is presented from which potential traceability parameters are then identified. The second investigation addressed the potential value of the SATRACK range instrumentation system to MX testing on the Western Test Range. Mathematical models describing the errors associated with the MX guidance system, the SATRACK system, and the environmental factors that affect system performance were developed. Particular attention was paid to the gravitational and ionospheric delay errors.


In this paper, performance evaluation and system level simulation have been done for the communication between the base station and train users, macro users. And an improved proportional fair algorithm has been proposed to ensure that train users are prioritized to get the resources and differentiate service priority transmission. By using this algorithm, train users will access to resources first. Under this premise, the service with higher priority will be assigned to resources preferentially. The simulation results show the proposed algorithm can improve the performance of the train users, as well as which of the service with a higher priority by the simulator.


The study aimed for Formulation development of floating tablet of venlafaxine Hydrochloride. Floating tablets is new era for successful development of controlled release formulation along with various features to provide successful drug delivery system. The purpose of the present investigation is to formulate floating tablets of Venlafaxine HCl, a novel antidepressant by direct compression technique using microcrystalline cellulose, HPMC, Sodiumbicarbonate. The drugexcipients interaction was ruled out through FTIR studies. The prepared batches were evaluated for organoleptic properties, hardness, friability, weight variation, parameters, buoyancy time, floating lag time and in- vitro dissolution study and stability. The drug content of all the formulations was within the acceptable limits of the British Pharmacopoeia. The release profile and drug content were remained unchanged after 1 month storage of tablets at 40 ± 2 o C and 75 ± 5% RH. In vitro dissolution study was carried out in pH 1.2 buffer. The in vitro drug release of optimised formulation followed Higuchi kinetics and the drug release mechanism was found to be non-fickian type.


A flexible micro-heat-pipe panel, fabricated by sintering an array of aluminum wires between two thin aluminum sheets, was developed as part of a program to develop lightweight, flexible radiator fin structures for use on long-term spacecraft missions. A numerical model, which combined both conduction and radiation effects, was established to predict the heat-transfer performance and temperature distribution of the radiator fin in a simulated space environment. Three different concepts are presented, evaluated, and discussed. Comparison of the predicted and experimental results indicated that the model developed herein can be used to accurately predict the temperature distribution and heat-transfer performance occurring in micro-heat-pipe radiators. This comparison further indicates that the flexible radiator with the array of micro heat pipes has an effective thermal conductivity of more than 20 times that of the uncharged version and 10 times that of a solid material. This results in a more uniform temperature distribution, which could significantly improve the overall radiation effectiveness, reduce the overall size, and meet or exceed the baseline design requirements for long-term manned missions to Mars.


Having been promoted from higher vocational training level to four-year undergraduate educational level, Xi'an Eurasia University is now facing the coexistences of four-year undergraduate educational program and vocational training program, of unified enrollment and non-unified enrollment. The author of this paper tries to make orientation of Xi'an Eurasia University in five areas including goal, level, type, specialized subject and service. Having referred to several domestic universities with four-year undergraduate educational program and taken the practical condition of Xi'an Eurasia University into account, the author comes up with the dominating ideas of the four-year educational program in Xi'an Eurasia University, which can be summarized as below: firstly, making an accurate orientation of the university and handling the relation between the four-year educational program and higher vocational training program; secondly, working out an educational plan for the four-year undergraduate program and sticking to the educational direction of "one major body with two wings"; thirdly, laying down various rules and regulations fit for the teaching management and student management in Xi'an Eurasia University.


Abstract The aim of this article is to bring together material from a range of media sources to provide an accessible and critical overview of the 1998 Australian waterfront dispute. It is argued that the dispute demonstrates the ways in which recent changes to Australian industrial relations policies represent both continuities and new directions. The outcomes of the dispute also demonstrate the dilemmas facing unions in resisting corporate and state assaults in an age of globalisation. Globalisation has created many new threats—but also some new opportunities—for labour movements around the world. A key lesson of the Australian waterfront dispute is that it is more true than ever that local and national struggles between labour and capital are now fought on a global stage and require transnational resistance and solidarity.


What are, from a general perspective, the explanatory goals of the contributions of this volume? How do they theoretically account for the puzzles indicated, and what are their empirical Ž ndings? The phenomena that this volume seeks to explain are threefold: the emergence of regulatory institutions (Gilardi); regulatory policy outcomes (S. Schmidt, V. Schmidt, Drahos and van Waarden, Héritier, Serot); and political outcomes of regulatory reforms (Thatcher). On the Ž rst topic, Gilardi asks which factors account for the rise of independent regulatory agencies to which governments have delegated power in different sectors, e.g. electricity, telecommunications, Ž nancial markets, food safety and pharmaceuticals. From the second perspective, S. Schmidt investigates the impact of mutual recognition on market integration, on the one hand, and European and domestic regulatory responses in the road haulage and insurance sectors, on the other. Van Waarden and Drahos study the impact of the European Court of Justice rulings and Commission decisions on the content of national competition policies, measuring policy convergence. V. Schmidt investigates national adjustment to European economic policy in sectors, such as energy, telecommunications; she points to different national responses, e.g. inertia, absorption or transformation. Serot focuses on the impact of privatization and the deregulation of telecom prices, Ž nding a clear convergence. Héritier analyses the policy impact of the liberalization of network industries, focusing on the provision of public services in rail transport and telecommunications services, identifying the underlying factors of service performance. Within the third perspective, Mark Thatcher scrutinizes the central political consequences of regulatory reform, e.g. for the relationship between independent regulatory authorities and elected politicians, the relationship with regulatees, decision-making practices and their democratic legitimacy. Thus, the explananda of the contributions in this volume reach from the emergence of new regulatory structures, to the outcomes of these structures at the policy level, including the underlying processes, to the structural impacts of the new structures on national polities.


Speech-language pathologists/therapists have been using a different service delivery model known for almost 40 years as telepractice, so they can meet the growing demand for assessment, intervention, consultancy, and also distance learning in their scope of practice. As far as the authors could review, the literature highlights a number of benefits for students, teachers, parents, and stakeholders, as well as evidence for the delivery of professional services at a distance within the clinical and educational settings. There are few studies regarding the effectiveness of telepractice intervention in this field. To their knowledge, there are no European Portuguese studies. The chapter illustrates up to date international applications of telepractice and distance learning in speech-language therapy services. It has currently increased in order to respond to the world crisis related to COVID-19 in which social self-isolation and personal dislocations are being implemented, forcing this professional to adapt to this new reality.


Simple Summary The DEAD-box RNA helicase 41, DDX41, is one of the most frequently identified mutations in myeloid neoplasms with germline predispositions, which represents 2% of the entire MDS/AML population. DDX41 is located at 5q35.3, and its mutation has unique features of male predominance and long-term cytopenia before the development of myeloid neoplasms. So far, mechanism studies revealed that DDX41 mutations, affected by both germline and somatic mutations, can be pathogenic by impairments in the normal function of genes involving RNA splicing and processing, ribosomal biogenesis, metabolism, cycle progression, and innate immunity. We are gaining a better understanding of disease from more studies coming out with larger cohorts. The survival impact of the mutation remains unclear, although recent larger studies suggest a better treatment response and survival in higher risk MDS/AML. Several studies showed a good response to lenalidomide in certain patients with MDS with DDX41 mutations. Early identification of stem-cell transplant donors in the family for patients with DDX41 mutations is crucial to avoid donor-derived leukemia from germline carriers. In this article, we reviewed the current understanding of DDX41 mutations in AML/MDS, including its pathogenesis and clinical characteristics, outcome, and treatment. Abstract The DEAD-box RNA helicase 41 gene, DDX41, is frequently mutated in hereditary myeloid neoplasms, identified in 2% of entire patients with AML/MDS. The pathogenesis of DDX41 mutation is related to the defect in the gene's normal functions of RNA and innate immunity. About 80% of patients with germline DDX41 mutations have somatic mutations in another allele, resulting in the biallelic DDX41 mutation. Patients with the disease with DDX41 mutations reportedly often present with the higher-grade disease, but there are conflicting reports about its impact on survival outcomes. Recent studies using larger cohorts reported a favorable outcome with a better response to standard therapies in patients with DDX41 mutations to patients without DDX41 mutations. For stem-cell transplantation, it is important for patients with DDX41 germline mutations to identify family donors early to improve outcomes. Still, there is a gap in knowledge on whether germline DDX41 mutations and its pathology features can be targetable for treatment, and what constitutes an appropriate screening/surveillance strategy for identified carriers. This article reviews our current understanding of DDX41 mutations in myeloid neoplasms in pathologic and clinical features and their clinical implications.


Under the global trend of low-carbon economy, the sustainable development of tourism is very important for the adjustment of economic structure, regional economic development promotion, and improvement of city taste, community environment and conditions of public service facilities. More and more leisure cities take their own tourism products as leader, which is becoming the comprehensive industry complex market to meet the leisure consumption of foreign tourists and local residents. The State Council clearly takes Chang-Zhu-Tan area as a "two-type" demonstration area. All society circles advocate establishing ecological civilization conception, to develop tourism rapidly and healthily is the objective and direction of Changsha, and their goal is to create "The Central Leisure Capital". Changsha is a leisure city in middle China, has their own main background resources for tourism development, such as long-depth history and cultural tradition, and their characteristic mountains, water, continents, and city landscape. And also urban residents have good recreational traditions. The tourism developed together with leisure industry, and now has form the economic structure and industrial clusters of main tourism, entertainment, service and cultural industries. Therefore, it is a practical issue to make the comprehensive study on sustainable development of tourism by using landscape ecology theory, which also is a breakthrough to predict the future development.


A new basic cell for low-power and/or low-voltage operation is identified. It is shown that different versions of this cell, called the "flip voltage follower," have been used in the past for different applications. New circuits using this cell are also proposed here.


The collection of works by Yannis Ritsos The Fourth Dimension was published in 1972. It comprised works written during the previous decade and they were presumably united on the basis of their structure and issues covered. It includes 17 works written as a theatrical monologue, 12 of them being inspired by antique topics.


We summarize work at the National Institute of Standards and Technology (NIST) to measure and analyse the spectra of iron-group elements using Fourier transform and grating spectroscopy.


Facial paralysis was first described in a hypertensive patient by Moxon1 more than a century ago. Subsequently, there have been reports2-8 that have included a number of children, and facial palsy is mentioned in standard pediatric references9,10 as a rare feature of hypertension. Even so, practitioners may fail to recognize that facial (seventh cranial nerve) paralysis can be the initial feature of severe hypertension in children. To increase the level of awareness, we describe three severely hypertensive children who were first seen with facial paralysis between 1980 and 1988. In one of these children the diagnosis of hypertension was delayed.


I was asked to read this bulky document and perhaps unwittingly agreed to do so. How does one review a total of 551 data sheets all properly indexed from 8.1–1 to 75.4–6? If you like numbers, they are here. A question in mind is, What does one do with all these figures?


Relative Lempel-Ziv (RLZ) compression has been shown to be effective for compression of large text repositories. It provides high compression ratios with extremely fast atomic decompression of individual documents. However, it depends on a large in-memory dictionary, which is implemented as a contiguous string that must be accessed randomly during the decompression process. In this paper we explore how compressed suffix arrays might reduce the size of the dictionary. These suffix arrays drastically increase the cost of accessing individual characters, however, so we propose splitting of the dictionary: an uncompressed structure for frequently accessed dictionary elements, with compression for the remainder. Our results show that splitting provides a smoothly tuneable trade-off between access time and memory requirements, but does not overcome the inherent limitations of compressed suffix arrays for this application, with decompression time growing by a factor of 10 for even the best combination of parameters. Suffix arrays comprise an attractive option where memory is limited, high compression is paramount, and decompression speed is unimportant.


In this paper we introduce the quantum white noise (QWN) conservation operator N acting on nuclear algebra of white noise operators L(Fθ(S ′ C (R)),F θ (S C (R))) endowed with the Wick product. Similarly to the classical case, we give a useful integral representation in terms of the QWNderivatives {D− t , D + t ; t ∈ R} for the QWN-conservation operator from which it follows that the QWN-conservation operator is a Wick derivation. Via this property, a relation with the Cauchy problem associated to the QWN-conservation operator and the Wick differential equation is worked out.


Abstract Background Knowledge of COVID-19 epidemiology remains incomplete and crucial questions persist. We aimed to examine risk factors for COVID-19 death. Methods A total of 80 543 COVID-19 cases reported in China, nationwide, through 8 April 2020 were included. Risk factors for death were investigated by Cox proportional hazards regression and stratified analyses. Results Overall national case-fatality ratio (CFR) was 5.64%. Risk factors for death were older age (≥80: adjusted hazard ratio, 12.58; 95% confidence interval, 6.78–23.33), presence of underlying disease (1.33; 1.19–1.49), worse case severity (severe: 3.86; 3.15–4.73; critical: 11.34; 9.22–13.95), and near-epicenter region (Hubei: 2.64; 2.11–3.30; Wuhan: 6.35; 5.04–8.00). CFR increased from 0.35% (30–39 years) to 18.21% (≥70 years) without underlying disease. Regardless of age, CFR increased from 2.50% for no underlying disease to 7.72% for 1, 13.99% for 2, and 21.99% for ≥3 underlying diseases. CFR increased with worse case severity from 2.80% (mild) to 12.51% (severe) and 48.60% (critical), regardless of region. Compared with other regions, CFR was much higher in Wuhan regardless of case severity (mild: 3.83% vs 0.14% in Hubei and 0.03% elsewhere; moderate: 4.60% vs 0.21% and 0.06%; severe: 15.92% vs 5.84% and 1.86%; and critical: 58.57% vs 49.80% and 18.39%). Conclusions Older patients regardless of underlying disease and patients with underlying disease regardless of age were at elevated risk of death. Higher death rates near the outbreak epicenter and during the surge of cases reflect the deleterious effects of allowing health systems to become overwhelmed.


OBJECTIVE
To analyze the clinicopathologic characteristics of well-differentiated hepatocellular carcinoma (WD-HCC), and to find clues for its pathologic diagnosis and differential diagnosis.

METHODS
Seventy-three cases of WD-HCC were studied with clinical data analysis, gross and microscopic examination.

RESULTS
Among the 73 cases, the prevalence of HBV (+) and/or HCV (+) was 94.5% (69/73), liver cirrhosis was 80.8% (59/73), increased hepatic cell density was 95.9% (70/73), dilated and irregular hepatic sinus was 89.0% (65/73), prominent trabecularism was 89.0% (65/73), increased cytoplasmic eosinophilia or basophilia was 90.4% (66/73), glandular-like structure was 16.4% (12/73, and fatty degeneration was 42.4% (31/73) .

CONCLUSIONS
There are important clinicopathologic features associated with WD-HCC. These features are useful in the differential diagnosis of WD-HCC with dysplastic nodule (DN), focal nodular hyperplasia (FNH) and hepatocellular adenoma.


This is a brief guide to the kinds of sources you may want to look at as you explore a research topic.


Abstract Anthocyanins are an important group of natural pigments that are responsible for many colours in plants. The variation in colour, depending on the pH, makes them a unique source of natural colourant. In this study, pigments from the fruits of Ixora siamensis and the fruit pulps of Melastoma malabathricum were extracted using trifluoroacetic acid–methanol solution. Spectral measurements (380–780 nm) were performed using visible spectroscopy with colour analysis software at different pHs (initial extracts were 1, 5, 7, 9 and 11). The colours of the solutions were expressed as colourimetric coordinates in the Commission Internationale de l'Eclairage (CIE) laboratory scale using L* (lightness), C* (chroma), H° (hue angle notation hab), a*/−a* (redness and greenness) and b*/−b* (blueness and yellowness) for the D65/2°CIE Illuminant/Observer condition. In this work, the colour parameters were observed for natural colourant with and without blending with polyvinyl alcohol for both species (Ixora siamensis and Melastoma malabathricum). The relationships between the colour parameters (colourimetric indexes and CIELab variables) with pH variation and species dependence were discussed in this paper.


This study evaluates the publications on church history, barely considered up to now, which deal with the Protestant Kirchenkampf (struggle between the German Christians and the Confessing Church) which started during the first years of the Nazi regime. It observes the different ecclesio-political groups and shows that as a rule the German Christians chose a descriptive and triumphalist portrayal of the Kirchenkampf which culminated in Andreas Duhm's Kircbengeschichte des Jahres 1933/34. The representatives of the Confessing Church on the other hand concentrated on the documentation of ecclesio-political events and theological confessions, since they were wary of censorship by the state. In this study, the author describes this form of documentation as a feature of the Confessing Church in Germany and deals with descriptions from Switzerland.


The Teacher Education system presented a kaleidoscopic picture both in variety and standards. Regional imbalances in the development of the system, differences in the competence, preparedness and standards of the teachers coming out and the teacher's educators themselves, immense variation in the programmes etc. made the system a complex and problematic area to deal with. NCTE had no inbuilt mechanism and human resources to develop and implement a quality monitoring mechanism, which has become an essential component for sustained quality in the TEIs. To enable the teacher to play his / her desired role as a catalytic agent, the programme of teacher education must take into account to meet the future needs of the society.  The present investigation has aimed to identify the contribution of the self financing teacher education institutions to the under privileged sections of the society which constitute  nine teacher training colleges and 270 students who are studying in this institution for identifying contribution in the various streams of the education and also what are the other assistants sponsored by self financing institution for the under privileged section of the society. The present study viewed the opinion from the stake holders of the institution and their level of satisfaction proves the service rendered by the self financing institutions for their development and achievement which is appreciable indeed.


The research in the fundamental principle and iteration steps of the simulated annealing algorithm is carried out. It is brought in the scheme generation for the overall elements of the aircraft carrier design. Taking account of the stability, celerity, seakeeping, operational effectiveness and the cost of the aircraft carrier, the minimum objective function model is built up. Overall optimization of elements is achieved according to this model in FORTRAN language. The results show that the global optimal solution can be efficiently obtained by using simulated annealing algorithm, without any limitation of the initial points. After the optimization, the stability, celerity, seakeeping, operational effectiveness and the cost of the aircraft carrier are sufficiently improved.


L-The Insurance Cyclopaedia : A dictionary of the definition of terms used in connection with the theory and practice of Insurance: A biographical summary of the lives of all those who have contributed to the development of Insurance: A bibliographical repertory of all works ivritten upon the subject of Insurance and its associated sciences : An historical treasury of Insurance: also a detailed account of the rise and progress of Insurance in Europe and in America. And a compendium of vital statistics. By Cornelius Walford, F.I.A., F.S.S. London : C. & E. Layton. Vols. I. & II. (from A to Equ), 1871-1874.


The 2006 REACH Regulation1 imposes information and notification requirements on importers and producers of "articles" containing substances of very high concern listed on the Candidate List (SVHCs) above a 0.1% threshold. Member State interpretations of the term "article," however, diverge. The specific issue dividing the Member States has been how the threshold should be applied to complex articles incorporating components that separately would also meet the definition of article (so an "article in article," or, as it is called in this note, a "component-article"), such as aircraft, cars, bicycles, motor bikes, lawn mowers, toys, furniture, clothing, machinery, household and industrial appliances, medical devices, and electronics (not all of which are covered by the RoHS Directive's chemical restrictions); some of these articles incorporate hundreds or even thousands of components. Most Member State authorities have concluded that the threshold applies only to the whole article, not separately to its componentarticles, but seven dissenting countries2 have taken the position that the threshold applies to each individual component-article; in the case of a laptop, for instance, the threshold would apply to each of the screen, plastic case, chip, board, wires, etc.3 This position is also known as "once an article, always an article."4 Needless to say, application of the 0.1% threshold to each component would increase the burden of complying with the pertinent REACH obligations. Specifically, the application of the limit value at the level of each individual component requires that companies collect more granular data on all component-articles.Where supply chains are long and complicated and extend around the world, this exercise becomes onerous. It would also limit an importer or producer's ability to switch suppliers of componentarticles. Inotherwords, in light of thenumberof component-articles some products include, how the current disagreement is resolved, matters a great deal. In April 2014, the Court of Justice of the European Union was asked to rule on the question whether the


Rheumatoid Arthritis(RA) is a refractory systemic autoimmune disease characterized by the damage of the peripheral joints.Chinese herbs and its active components are effective and safe,less side effective on the treatment of rheumatoid arthritis.This paper reviews the general situation on the therapy of rheumatoid arthritis with the effective substance of the Chinese herbs.


The article discusses the concept of investment risks, features of investment and construction activities, the need for risk assessment. The possibility of their modeling and evaluation using application software is considered. The methodology and calculation of risk assessment of the investment project using the analysis tools of the application software Excel package is proposed.


Purpose - The study aims to analyse the level and trend of corporate responsibility disclosures (CRD) in annual reports of listed firms on the Ghana Stock Exchange against the Global Reporting Index and to examine the influence of the institutional environment on such disclosures. Design/methodology/approach - A content analysis of annual reports of 17 listed firms in Ghana over a 10-year period (2003-2012) of social and environmental disclosures using the Global reporting indicators as the standard was undertaken. A multiple regression analysis using the random effect estimator was used to test institutional factors influencing CRD. Findings - The study finds that listed firms in Ghana disclose some responsibility information; and this has increased over the period, with a significant dip in the year 2010. The study also documents a significant amount of disclosures post International Financial Reporting Standards (IFRS) adoption. The increase in disclosure is particularly explained by IFRS adoption by Ghana and the number of women on boards. This study finds a positive but weak relationship between companies' association with foreign firms, majority shareholders and CRD. A positive significant relationship is confirmed for firm size, while capital intensity shows a negative significant relationship with CRD in Ghana. Research limitations/implications - The word search may not capture similar words not known to the author, and the words used may have different meanings. In addition, bias may arise from the limited sample size and the choice of companies. Regulators must enforce existing environmental guidelines and streamline reporting for social and environmental issues to help managers disclose more social and environmental information. Originality/value - The study highlights CRD and its drivers from Ghana, an emerging African economy. To the author's knowledge, this study is the first to undertake a longitudinal study on social and environmental disclosures of listed companies in Ghana against the Global Reporting Initiative and to determine the effect of IFRS adoption in Ghana on CRD.


In the doctor's waiting room, sick(病的) men and women were sitting on chairs. Bob, a school boy, was there, too. They all looked very sad 1 Bob. He was deep(深的) in an 2 story in a book. Just then the doctor came in and said he was。


DOI: 10.21276/sjebm.2018.5.11.9 Abstract: This study aims to determine the influence of organizational culture and career development on employee performance simultaneously, knowing the influence of organizational culture on employee performance partially, knowing the influence of career development on employee performance partially, knowing influence of motivation on employee performance partially, knowing the influence of organizational culture on employee performance through motivation and determine the effect of career development on employee performance through motivation. The study was conducted on the employees of the Tax Office Primary North Bekasi. The sampling technique using saturated samples involving 80 people. Analysis of data using path analysis. Based on data analysis known that variable of organizational culture and career development affect the performance of employees simultaneously. Organizational culture and career development affect the performance of employees partially. Motivation variable influence on employee performance partially. The influence of organizational culture and career development on employee performance through motivation direct influence greater than the indirect effect so that it can be said that the motivation variable not as an intervening variable.


This research is divided into four chapters, the same as detailed below:

In Chapter I Framework, in which is the whole objective of this work is to determine how the action for breach as a constitutional guarantee legal effects on the litigants in the judgments of the constitutional court is in 2015, in relation to the specific objectives of a legal, critical and doctrinaire study of the action it is done by default as a constitutional guarantee, as well as determine the relevance and impact on the litigants.

In Chapter II the theoretical framework is developed, the same as a study concerning Action is included by default as a constitutional guarantee, subject of which an analysis of its definition, its characteristics, importance, procedural and especially was made the legal effects of the action for breach occurs as a constitutional guarantee the litigants as damages, reparation, demand the state and judgment of repetition, etc. the judgments of the Constitutional Court.

In Chapter III field research it has been held in the Constitutional Court, based on the judgments issued by that institution in 2015. Also in this chapter the discussion of results and examination of applied develops hypothesis.

Finally, in Chapter IV the conclusions and recommendations are developed on the issues that I consider most important right and outstanding of this research.


A body fat measurement apparatus, according to the present invention, comprises: an electrode unit which has a plurality of electrodes and can be worn around the body of the subject to be measured; a first measurement unit which is for obtaining a three-dimensional image of the subject's body part to be measured; a second measurement unit which is for measuring the impedance by means of injecting a current into the electrodes; and a control unit which is for restoring the conductivity and permittivity images of the subject by means of the three-dimensional image and the impedance value and thus separately calculating the amount of subcutaneous fat and visceral fat. According to the present invention, measurement accuracy of the subcutaneous fat and visceral fat can be improved even at a low cost.


Among various data mining concepts like prediction, clustering, classification, association and outlier discovery, association is a useful technique to extract the interesting relations among data items effectively. Association technique is applied in a number of applications like marketing, education, chemical, bioinformatics, computational linguistics and etc. The important purpose of association is to provide useful information of buying preferences of customers in supermarket in order to increase the sales opportunity, which is called as market- basket analysis. Till now there are many algorithms were developed, but the usage of formal grammars in association rule mining (ARM) is a latest technique to mine required data by means of grammars. In this paper ARM is performed using Context –free Grammar (CFG) – (ARM – Grammar) and the experiments are conducted on MATLAB 2017 software using network dataset, KDDCUP'99. Experimental outcomes prove that the proposed ARM – Grammar is effective than the traditional ARM approach.


OBJECTIVES
To examine whether inhibition of NF-kappaB induces apoptosis of human synovial cells stimulated by tumour necrosis factor alpha (TNFalpha), interleukin 1beta (IL1beta), and anti-Fas monoclonal antibody (mAb).

METHODS
The expression of proliferating cell nuclear antigen (PCNA), NF-kappaB, and the presence of apoptotic synovial cells were determined in synovial tissues. Apoptosis of cultured synovial cells was induced by inhibition of NF-kappaB nuclear translocation by Z-Leu-Leu-Leu-aldehyde (LLL-CHO). The activation of caspase-3 and expression of XIAP and cIAP2 in synovial cells in LLL-CHO induced apoptosis was also examined.

RESULTS
Abundant PCNA+ synovial cells were found in rheumatoid arthritis (RA) synovial tissue, though a few apoptotic synovial cells were also detected in the RA synovial tissues. Nuclear NF-kappaB was expressed in RA synovial cells. Electrophoretic mobility shift assay showed that treatment of cells with TNFalpha or IL1beta significantly stimulated nuclear NF-kappaB activity. A small number of apoptotic synovial cells expressing intracellular active caspase-3 were found after treatment of cells with LLL-CHO. Although treatment of RA synovial cells with TNFalpha or IL1beta alone did not induce apoptosis, apoptosis induced by LLL-CHO and caspase-3 activation were clearly enhanced in TNFalpha or IL1beta stimulated synovial cells compared with unstimulated synovial cells. Furthermore, induction of apoptosis of synovial cells with caspase-3 activation by anti-Fas mAb was clearly increased by LLL-CHO. The expression of cIAP2 and XIAP in synovial cells may not directly influence the sensitivity of synovial cells to apoptosis induced by LLL-CHO.

CONCLUSION
The results suggest that NF-kappaB inhibition may be a potentially important therapeutic approach for RA by correcting the imbalance between apoptosis and proliferation of synovial cells in RA synovial tissue.


OBJECTIVE
To study the effect of long-term use of low dose Caulis Aristolochiae Manshuriensis (CAM) on the deterioration of chronic renal failure rats.

METHODS
The 5/6 nephrectomized Wistar rats were taken as animal model of chronic renal failure, which were divided into 3 groups. Group A was treated with 1 g/kg CAM decoction, the dose equivalent to that defined in the pharmacopoeia. Group B was treated with 3 g/kg CAM decoction and Group C treated with equal volume of tap water. Medication was given once per day by gastrogavage in all the three groups for 8 weeks. The serum creatinine, urea nitrogen, urinary protein content and morphological changes of kidney were observed.

RESULTS
After 8 weeks treatment, levels of serum creatinine, urea nitrogen, urinary protein excretion in Group B were higher than those in Group C significantly, they were 165.0 +/- 15.6 mumol/L vs 109.8 +/- 10.0 mumol/L, 27.8 +/- 3.6 mmol/L vs 18.7 +/- 2.5 mmol/L and 68.2 +/- 10.1 mg/24 hrs vs 44.6 +/- 8.5 mg/24 hrs, respectively, all P < 0.05. The pathological changes of renal mesenchyme and degree of glomerulosclerosis were also heavier in Group B.

CONCLUSION
The susceptibility of chronic renal failure rats to the nephrotoxicity of CAM increases in long-term use of low dose CAM which could accelerate the deterioration of renal impairment in the model rats.


A vessel can produce an external magnetic field by the deformation of the Earth's field, and shipboard-type electrical equipment can in addition generate permanent or low frequency magnetic fields. Geophysical ships, as well as minehunters form a specific class of magnetically silent ships, for which it is desirable to significantly reduce the external magnetic field. The authors suggest using magnetic energy as a general measure of overall source intensity. The total magnetic energy outside a boundary surface can be expressed in terms of the harmonic expansion coefficients for the magnetic scalar potential. For specific characterization of the magnetic field distribution near the source, the authors suggest the use of isodynamic surfaces of constant magnetic field energy density (BH/2). The isodynamic surfaces are useful for identifying regions where the magnetic field extends furthest from the vessel or on-board equipment. They can also be used to determine magnetic properties of the source.


On the basis of the system approach the algorithm of the decision of a task of psychological support of cadets of the educational military center which is taking place civil vocational training within the framework of university education is considered. Conceptual bases and functions of psychological support, their realization during training cadets are shown.


The Mesolithic First, information relating to the management of raw materials in the Mesolithic is summarised; then attention is turned to the use of stone raw materials and their distribution in the LBK (map 10). Mesolithic finds in Moravia are scarce. Only the finds from the site at Smolín are stratified (Valoch 1978), with the others coming from surface collection. On the basis of typological analyses, most of the sites in south Moravia can be dated to the latter half of the Boreal and to the period at the end of the Boreal and the beginning of the Atlantic. Some of these sites were probably settled repeatedly (Smolín, Přibice, Mikulčice; Vencl 1993, 149). In Lower Austria, too, the Mesolithic is known only from surface sites, with the exception of Kamegg (Leitner 1984; Antl-weiser 1986, 192–220). In northern Hungary, topographic survey at the beginning of the 1990s identified Mesolithic sites in the north of the Great Hungarian Plain, where according to some authors Mesolithic settlement was not to be expected (Kertész 1994a, 24). The sites of Jászberény I and Jásztelek I are also documented stratigraphically, and radiocarbon dates have been obtained from Jászberény I (Kertész et al. 1994, 28; Kertész 1996a).


This paper presents an end-fire antenna with circu-lar polarization utilizing gap waveguide technology for 77 GHz automotive radar band. The proposed device contains a 1 × 4 planar array antenna and a gap waveguide part consisting of a 4-way power divider on ridge gap waveguide and a transitive groove gap waveguide. The impedance and 3-dB axial ratio bandwidths of 74.8 ~ 79.2 GHz and 75.6 ~ 78.0 GHz are achieved in simulation, which can cover the 77 GHz radar band well. A stable end-fire beam and a gain in the range of 11.6 to 13.4 dBic are obtained as well over the whole operation band.


Procedures for calculating intersection left-turn capacities and determining left-turn bay and protected phase requirements were developed in Report 258-1 of Study 3-18-80-258, "Guidelines for Left-Turn Treatments." In addition, Report 258-2 developed guidelines for choosing left-turn phase sequence patterns. The procedures and guidelines from the two reports are synthesized and presented in a stepwise format. A series of example problems is included to illustrate the procedures and facilitate usage. (Author)


A single specimen of the invasive American blue crab Callinectes sapidus was captured at a depth between 0.5 and 1 m, by a fisherman in August 2018, near the estuary of the Oued Z'hor, in the eastern part of the Algerian coast. This report represents the first record of this species from Algerian coastal waters. Callinectes sapidus has widely invaded European Atlantic coasts and several areas of the Mediterranean, probably through ballast waters. However, information is still insufficient to ascertain the origin and mode of introduction of this species into the Algerian coast.


This study explored different types of positive teacher efficacy, and analyzed the likely consequences of each for educational reform. The study drew from two sources: an analysis of more than 200 articles on teacher efficacy and educational reform, and a 4-year qualitative study of the relationships between three elementary teachers' efficacy beliefs and their efforts to teach mathematics in more reform-oriented ways. Eight types of positive teacher efficacy that may obstruct educational reform were identified. Each potentially problematic type of teacher efficacy is described in relationship to the three teacher cases, or the literature review, or both. Past teacher efficacy research is reanalyzed in light of these findings. The importance of teachers' efficacy interpretations and qualitative distinctions between different types of teacher efficacy beliefs is discussed. One such distinction relates to the type of teaching (e.g., traditional or progressive) that forms the basis for a teacher's efficacy beliefs. The implications of these findings are related to recent suggestions to use teacher efficacy as a focus for teacher education and educational reform.


A computer simulation by Saila and Shappy (1963. J. Cons. Int. Explor. Mer 28: 153–166) indicated that the migrations of Pacific salmon (Oncorhynchus) from high seas feeding areas to the coastal vicinity of their natal stream may be accomplished with only slight homeward orientation. Five assumptions in this important paper are here reexamined to determine the validity of the original conclusion in light of current knowledge of Pacific salmon biology. It appears that assumptions concerning swimming speed, duration of migration, and return success were incorrect. These errors resulted in substantially underestimating the extent of salmon homeward orientation. Thus, contrary to the original conclusion, any hypothesis concerning the high seas migrations of salmon must explain the strong orientation of these fishes in the open ocean.


The world's population is growing and it is predicted that by 2050, 30% of the population will be >65 years of age.1 People >85years are the fastest growing cohort in Europe and will soon be 30% of all people aged>65 years of age. Many of the very old (>85 years) older people are not healthy in old age, as defined by the World Health Organization;2 many will have one or more long-term condition such as diabetes, heart disease, lung disease, osteoarthritis and osteoporosis.


In recent years, with the development of electric vehicles that require bidirectional energy flow, bidirectional DC-DC converters have taken a big leap forward along with it. Compared with conventional converters, this essay proposes a bidirectional DC-DC converter with high buck and boost gains. This topology can achieve high gain buck-boost of voltage by varying the duty cycle and turns ratio of the coupled inductor. In addition, this converter can switch freely among six bidirectional operating modes, increasing the operating modes of bidirectional DC converters, and also improving the width of voltage regulation. The operating principle, operating mode, and operating states of the converter are discussed in detail. In order to verify and confirm the feasibility of the proposed circuit, simulating different inductor turns ratios and duty cycles are carried out in PSIM. The simulation results are provided to validate the feasibility of the proposed converter.


A system and method are presented for authorizing execution of requested actions transmitted between clients and servers of a data processing system. The method includes receiving a message including a set of actions and simulating execution of the set of actions. A list representing allowable actions and user-definable inputs to the simulated actions is defined. The list of allowable actions and user-definable inputs to the allowable action is then compared to user-requested actions and inputs. When elements within the user-requested actions and inputs are included in the allowable actions and input list, the user-requested actions and inputs are authorized for execution.


This study reports on the results of three experiments investigating the modes of resolution with inconsistent information. Ninety subjects were given 11 disposition terms which involved the discrepant dispositions. The task was to describe the impressions of stimulus person. The results showed it was confirmed that 80% of subjects described the person who had both discrepant dispositions. And 7 categories for modes of resolution with inconsistent information were classified. Then it was shown that the estimations of the "logical consistency", "reality for an image of person" and "introspection of person" were differernt between groups of modes of resolution (I, II, III). In other words when we integrate inconsistent information in terms of more organaized mode, the estimation of the introspection of person was higher. Therefore it was suggested that there is a close relationship between the organized integration on the inconsistent information and the level of cognitive resolution.