Ready. Set. Go. The Experiential Education seminar at Pingree Park was my first course with the Adult Education and Training Masters at Colorado State University. With years of teaching and guiding in the field, I knew this week would be part refresher and part new material for me. My intention was to allow a synthesizing of my experience with my willingness to show up as a learner. Learner hat. Leader hat. I was curious, vulnerable, committed, reflective. And a little scared. With all the huge changes in my personal and professional life right now, what the hell was I thinking going back to school? How could I frame this as a strong, wise choice and not just an shot at huge overwhelm?One of the most insightful points in the week for me was during the challenge course on the second day of the seminar. It had been years since I had a climbing harness on. The last time I had, the facilitator had had to keep upping my tasks on the ropes to get me to reach my edge of comfort. So at first, when I put the harness on, I felt a little bit like things were going to be easy for me and I'd have to dig for a challenge. Down deep, though, I heard a much more vulnerable voice in me. I knew to expect a few metaphors.The challenge I decided to take first was the Leap of Faith. We'd climb up a 25 foot pole, stand on the top and then leap from that pole to reach for a trapeze that was up and away from the top of the pole at what seemed like a do-able distance, at least from down below. I thought this would be an apropos metaphor for my life right now. I was right.I decided to practice on the smaller practice pole first, mostly for the transition from the climb to the stand. I'm a mountain woman - a hiker, a dancer, a skier - heck I even used to play ice hockey. I think of my legs as strong and my knees as part of that strength. Going from a squat to a stand didn't seem like a huge challenge for me. So it surprised me when I got to the top of that little pole and I couldn't go from a squat to a stand. My legs just wouldn't unfold. I could get one foot up there, but I was having trouble mastering the transition from that folded up climbing position to standing on the little space that was the top of the pole. I was a little perplexed by that. I kept trying. No go.Here I was going back to school at 54, to get the Masters Degree I'd always wanted to go for. There had been plenty of great opportunities to go back to school, especially before I became a mother, but I kept putting it off and putting other things (jobs and people) first. I would just get it later. I couldn't just couldn't quite unfold my legs, I guess.Well, I tried climbing that practice pole again and I had the same trouble. I couldn't make the transition. I decided to try the big pole anyway. I think I was the 3rd person up, and the first two people had made it look pretty simple. Travis had just scampered right up there, stood up and jumped - at least that's the way it seemed.I climbed up the pole, feeling a little woozy, and I had to remind myself not to look down. It was a lot taller than that little one. I got to the top and I had to hang on to the rope that went to my harness in order to stand up. If I was going to accomplish this task the completely cool way, I wouldn't grab that rope. But there I was and I needed it, so I used it. The wind was blowing and I wanted to succeed. My legs slowly unfolded. And I stood up. I let myself stay there for a while and feel the wind, feel my fear. Here on top of the pole with my feet standing as close as they could be together, standing on top of this tree, that trapeze now seemed very far away.I was nervous about my leap. As a matter of fact, I can remember the sensation of my legs locking a little. How would I bend my knees to get a good jump? I felt a wave of emotion ride up my body and I thought I was going to cry.It felt like a long time, but who knows how long it really was. At last, I could tell it was time to just jump. …


The methodological section did not provide sufficient detail on how the different time step data were aggregated to SEBS inputs for the calculation. We will add a new section to the revised manuscript dealing with "Model parametrization and dataset preparation" to clarify this issue. The monthly ET calculation using SEBS was demonstrated by Chen et al. (2014). The structure of the model was not changed regardless of whether it was used for instantaneous, daily or monthly ET calculations. The difference in its implementation was only due to the input datasets. For monthly ET calculation, monthly mean LST, air temperature, wind speed, downward shortwave radiation, downward longwave radiation etc were used. The accuracy of monthly LST, a key variable in SEB models, was evaluated by Chen et al. 2017, supporting its applicability for climate studies and numerical model evaluation.


Background and Objectives: In this study, we aimed to investigate the link between common -2548G>A (rs7799039) promoter variant of the human leptin gene (LEP) with leptin and serum glucose leptin levels in obese Saudi patients. Materials and Methods: A total of 206 Saudi adults (80 obese normotensive nondiabetics, 76 obese hypertensive with Type 2 Diabetes and 50 normotensive nondiabetic controls) were genotyped for -2548G>A LEP polymorphism using the polymerase chain reaction-restriction fragment-length polymorphism technique. Results: Participants with minor AA genotype had significantly higher blood glucose levels (6.8 ± 0.55 mmol/L vs. 5.8 ± 0.30 mmol/L; p < 0.04) and HOMA-IR (4.1 ± 0.84 vs. 2.6 ± 0.67; p = 0.03) against those carrying major GG genotype. Participants with heterozygous GA genotype had significantly higher serum leptin levels against those carrying major GG genotype (40.0 ± 2.6 ng/mL vs. 29.6 ± 2.6 ng/mL; p = 0.04). Further investigation showed that individuals with AA, GA, GA + AA genotypes are at greater risk of developing hyperglycemia compared to those with GG genotype [OR 3.7(1.6–8.4), p = 0.001; 3.2 (1.2–8.6), p = 0.03; 3.5 (1.6–7.7), p = 0.001, respectively]. Additionally, the -2548AA allele was shown to be a risk factor for hyperglycemia [OR 1.9 (1.2–3.0), p = 0.006]. Our data revealed no relationship between this variant of the LEP gene with systolic and diastolic BP, signifying that this genetic variant is not a significant marker of obesity and hypertension in the Saudi population. Conclusions: AA and GA genotypes and LEP gene -2548AA alleles may signify potent risk factors predisposing healthy individuals to develop T2DM regardless of blood-pressure profile.


The listed companies' ultra-ability cash dividends payout has already arisen broad attention,but the likely market reflection resulted by this phenomenon was still not clear.By using empirical analyzing method,the authors chose the listed companies of Shanghai and Shenzhen stock market that conducted ultra-ability dividends payout in the year 2005 as the research object,compared the stock price data that before and after dividend announcement day,conducted the CAR empirical study,and then analyzed the market reflection to ultra-ability dividends payout.Finally the study result indicates that the ultra-ability dividends payout has negative signal transmission effect on the companies' stock price


The same wind that wafted on one of its wings the defeat of the French fleet in the West Indies, attended with a slaughter and carnage hitherto unknown, conveys the happy tidings of ireland's emancipation on the other, balanced in the calm air of steadiness and unanimity. English valour has triumphed over French pride, and Irish perseverance has broken England's stubbornness. Freeman's Journal, 21 May 1782


Abstract There is little known about the effect of hospice post-disaster. This study utilized exposure to Hurricane Irma (2017) to evaluate the differential mortality effect of the disaster on Florida NH residents (N=45,882) compared to a control group of residents in the same NHs in 2015 (N=47,690) by hospice status. We also examine the difference in hospice utilization rates post-storm for short- and long-stay (LS) residents. There was an increase in mortality for those in the cohort not on hospice within 90 days in 2017 compared to 2015 (OR= 1.06, 95% CI: 1.01, 1.11). For the rate of hospice enrollment post-storm among residents previously not on hospice, there was an increase among LS residents within 30 days (OR =1.15, 95% CI: 1.02, 1.23) and 90 days (OR= 1.12, 95% CI: 1.05, 1.20). It is important to further examine the increase in the rate of hospice enrollment in LS NH residents post-storm.


The state-to-state differential cross sections of rotational excitation at incident energy 64.0meV and elastic,inelastic and total differential cross sections are calculated for He atom collision with ground state N_2 molecule by employing accepted exact close-coupling approximation method at incident energy of 27.3,40.0,64.0 and 80.0meV,respectively.Then the changing regularities of differential scattering cross sections are summed up.It shows by investigation that elastic scattering takes place mainly at small angle,at the same time,inelastic scattering of rotational excitation chiefly at large angle while low-energy scattering for He-N_2 system.


Impact-modified polypropylenes were prepared by incorporating copolymers of ethylenemethacrylic acid (E-MAA) with different cations (zinc or sodium) and varying degrees of neutralization. These blends gave low stress whitening on impact. This phenomenon was due to the unique morphology of the blend. It was found that unneutralized acid copolymer and the zinc ionomer formed chainlike structures in the polypropylene matrix. These uniform chains crisscrossed the polypropylene matrix providing impact strength to the matrix. The matrix deformed on impact by the shear yielding mechanism, thus suppressing stress whitening. The impact modifier in the matrix did not form micro crazes in the matrix but formed several layers of crisscrossing chains. On the other hand, the sodium ionomer did not form chainlike structures. The impact modifier was dispersed evenly in the matrix. This type of morphology resulted in a higher degree of stress whitening. The failure on impact was due to crazing and not by shear yielding. This size of the impact modifier in the polypropylene matrix varied significantly depending on the melt processing equipment used. The dependence of polymer alloy mechanical properties on the composition has been studied to help in ionomer comparison.


Using finite element method,the continuous extrusion process of cable aluminum sheath on SLJB630 Konform machine was numerically simulated. The velocity,temperature,stress and strain fields were observed. The Φ150 mm × 2. 8 mm cable aluminum sheath was produced. The simulation result and the experiment data fits well,which proves that the FE model is precise,and it can be used as a theoretical guidance for die optimized design of big size cable aluminum sheath.


The article substantiates the timeliness, significance and necessity of the development of the motivation mechanism of work behaviour enh ncement of the hospit lity industry employees. On the b sis of the uthor?s classification of labour behaviour motivators, the motivation mechanism model of its enhancement as an open system has been developed and its formation stages and targets under the scenarios approach have been defined. Six groups of motivators of labour activity of hospitality industry employees are reasonable to monitor: material motivation (incentives), wide social motivation, participation, motivation of affiliation, procedural motivation, motivation to self-actualization. The factors discouraging labour behaviour of hospitality industry employees have been systematized and the mitigating measures have been identified. The article proved that the path to effective management of work behaviour lies through understanding each employee?s incentives, their person l work motiv tion, which is set of external and internal forces (incentives) encouraging the implementation of certain work efforts. The authors present an argument in favour of the complex use of various forms of incentives (material and non-material) which can be applied to the hospitality industry employees.


Abstract— Phosphors that absorb blue light and emit in the green, yellow, and red have been synthesized, and their experimental and theoretical luminous efficacies are compared. It is proposed that a blue‐emitting LED in combination with red‐emitting Sr2Si5N8: Eu2+ and green‐emitting SrGa2S4: Eu2+ phosphors is used as an energy‐efficient white‐light source for display backlighting applications.


Turmeric (Curcuma longa L) leaf oil and 1 hr & 2hr fractionally distilled oil was extracted through hydosteam distillation. GC analysis was carried out to find the major components. Physico-chemical characters of all the three samples have been compared. A cock tail mixture of 1st & 2nd hrly distilled leaf oil at 1:1 ratio were also used in the study. All the four samples (pure leaf oil, 1st and 2nd hr distilled oil and the cocktail mixture) showed antifungal activity against five human pathogens viz. Candida albicans, Cryptococcus neoformans, Trichophyton rubrum, Sporothrix schenckii and Microsporum gypseum. All the four samples were observed to be fungicidal against the above pathogens. The minimum inhibitory concentrations (MIC) and Minimum Killing Time (MKT) of the samples against these pathogens is also reported. The cocktail mixture and pure oil showed lower MIC and quicker MKT. Finally, the activity of the four samples were compared with standard antifungal drugs.


Allergic rhinitis (AR) is a common childhood disease. At the same time, there is an underdiagnosis of this condition in the clinical practice and its significant impact on the life quality of the patient and his family. The article describes a modern stepwise approach in complex AR therapy in children. This approach involves the choice of drug therapy in accordance with the disease course. In this case, it is necessary, in particular, to take into account the clinically significant sensitization profile, the presence of concomitant allergic and non-allergic pathology, the patterns of the expected exposure of relevant allergens, the disease course severity, the patient's age, response to therapy, etc. The current problems of conservative treatment are discussed. Information on the pharmacological drug groups for the AR treatment is presented: H1-antagonists, antileukotriene drugs, intranasal glucocorticosteroids. The main effects and the most common adverse events of their usage are considered. Practical issues of AR treatment tactics, relevant for pediatricians, allergists and otorhinolaryngologists, are highlighted. The prescription of drug combinations of different groups is substantiated, providing a simultaneous effect on different links of the pathogenetic process. The importance of elimination measures and allergen-specific immunotherapy is noted. KEYWORDS: allergic rhinitis, sensitization, H1-antagonists, leukotriene receptor antagonists, glucocorticosteroids, children. FOR CITATION: Asmanov A.I., Konyukova N.G., Pivneva N.D. et al. Comprehensive treatment method for children with allergic rhinitis. Russian Medical Inquiry. 2021;5(5):348–352 (in Russ.). DOI: 10.32364/2587-6821-2021-5-5-348-352.


We have examined two aspects of the dynamics and biogeochemical significance of the physical environment in Lake Biwa. One is the horizontal distribution of cyanobacteria as it relates to the 'first gyre' in the north basin of Lake Biwa. We could easily measure the first gyre using a vessel-mounted acoustic doppler currents profiler. We were able to quantify the dynamics of the horizontal and vertical structure of currents and water temperature of this gyre. The first gyre did not remain at a fixed position; it moved north and south according to the growth of the gyre. This may play a role in the redistribution of cyanobacteria from place to place in the north basin. The second important environmental dynamic we measured was oxygen consumption rates from 1994 to 2000. We found that the minimum oxygen concentration in the hypolimnion has a clear inverse relationship with the apparent oxygen consumption rates in the 80–85 m depth layer. As a reduction in oxygen concentration in the hypolimnion can have a serious impact on benthic organisms, we concluded that the Lake Biwa environment should be monitored carefully and systematically.


Background: The long-term survival of postoperative anastomotic leakage (AL) following gastric cancer (GC) surgery is still debating. Our aim was to investigate the association between AL and survival of the patients following GC. Methods: We searched articles in databases from inception to July 2023 to retrieve literature related to postoperative AL and survival of GC patients. We evaluated the association of postoperative AL and survival of GC patients using the software STAT10.0. Results: Seven articles with 6209 GC patients were included. Our results showed that the postoperative AL were associated with pooled 1-year patient overall survival (OS) result in an odds ratio (OR) of 0.504 (95% confidence interval (CI): 0.372–0.682; I2 = 84.1%; P = .000), pooled 3-year patient OS (OR = 0.467, 95% CI: 0.356–0.614; I2 = 85.3%; P = .000) and pooled 5-year patient OS (OR = 0.370, 95% CI: 0.171–0.805; I2 = 82.5%; P = .012). The P value of Egger test were 0.759, 0.187, 0.175. The postoperative AL were associated with pooled 1-year patient disease-free survival (DFS) result in an OR of 0.538 (95% CI: 0.171–1.691; I2 = 89.0%; P = .289), the pooled 3-year patient DFS (OR = 0.143, 95% CI: 0.119–1.431; I2 = 91.7%; P = .163), and the pooled 5-year patient DFS (OR = 0.344, 95% CI: 0.088–1.338; I2 = 91.0%; P = .124), and the P value of Egger test of pooled 1-, 3-, and 5-year DFS were 0.759, 0.247, 0.07. Conclusion: Postoperative AL was correlated with a worse OS in GC patients, but not correlated with DFS in GC patients, but more studies are required to confirm this conclusion.


in author's point of view,social insurance auditing work has achieved outstanding results.However,because of the lag of social insurance legislation,social insurance auditing work still has some problems.The government needs to speed up the progress of social insurance legislation,improve relevant laws and regulations and strengthen inter-regional,strengthen the responsibility of the government,inter-sectoral collaboration,in order to make social insurance auditing work improve the social insurance fees collected timely and rightly,safeguard legitimate rights and interests of insured persons,prevent the outflow of funds and ensure the safe operation of the funds.


C ontinuous prestressed concrete beams are used frequently in framed strictures, bridges and guideways. These beams offer many advantages over simply supported beams, but continuity causes some complications which must be considered in design. One such complication is the determination of stress resultants. The bending moments in a continuous beam can be predicted using a linear elastic analysis, provided the load level is such that the elastic limit is not exceeded in any ofthe constituent materials. When the elastic limit is exceeded at any particular load level, the bending moments in the beam may differ from those predicted by a linear elastic analysis and a nonlinear analysis is reManager Track and Structures Research Canadian Institute 4 of Guided Ground Transport • Queens University • Kingston, Ontario, Canada


Discussion and authors' closure of paper 45–97 by C. H. Braithwaite, Jr., and G. L. Moses, published in AIEE TRANSACTIONS, 1945, August section, pages 580–3.


In this paper,the angle compensation in di fferencial indexing was analysed through the calculation of some real examples and the results from positive and negative angle compensation calculation showed the required indexing angle on the workepiece has nothing to do with the assuming number.


In the present research, inelastic behavior of cold-formed steel frames with strap bracing was studied under cycling loading using finite element (FE) method. All of frame members including tracks, studs, and braces were modeled using two dimensional shell elements. The screw connections of braces to studs were simulated using connector elements. The shear and axial strength of screws were determined considering the screw pull-out and hard contact of braces to studs. The failure mechanism and resultant base shear were compared with the experimental measurements. The results showed a good agreement between developed FE model and experimental data. The shear and tensile forces of screws at different stages of loading, as well as the behavior in elastic and inelastic regions, were evaluated using the developed model. It was concluded that the buckling and yielding of braces are the most effective factors on the cyclic behavior of cold-formed steel frames; and that cyclic behavior of cold-formed steel frames with strap bracing can be accurately determined using the proposed FE model.


This study aims to validate the development of cost accounting practice modules so that they are more effectively used by students in the learning process. This type of research is descriptive research that will describe the validation process from module development to finding results about module validity that has been compiled. The source of research data was obtained from module validation sheets which were assessed based on each indicator by two experts. Data analysis techniques were carried out qualitatively and quantitatively. Data from the module validation sheet were analyzed quantitatively, and then descriptive techniques were used to draw qualitative conclusions. The results of the study indicated that the modules that have been designed were eligible to be used in the learning process of cost accounting practice courses at STKIP PGRI West Sumatra. These results were based on the results of material validation with an assessment of four indicators, namely the suitability of the material with competency standards, the accuracy of the material, supporting learning material and material updating with an average score of 3.2 by each expert. Expert advice for module improvement before practicing practice is that it is necessary to add information in the example of problem calculation and improvement in language writing.


Using microwave electron-cyclotron-resonance plasma-enhanced chemical vapor deposition, diamond-like carbon films were directly grown at low temperatures (lessthan equal to400°C) on Fe-based alloy substrates without diamond seeding or use of a template layer. A single, broad line in the Raman spectra was observed in the region of 1328-1335 cm-1 for films grown in gas mixtures with a ratio of CH4:H2 greaterthan equal to 2%. In contrast, disordered carbon and graphite phases appeared in the spectra for film grown with a concentration of 20% CH4 in hydrogen. Diamond nucleation with an amorphous carbon layer was observed in the initial growth stage, while many diamond particles with irregular morphological features were observed on the surface of thicker films. These growth features are a consequence of the catalytic nature of the Fe-based substrate.


164Background: Peer support among cancer patients is understudied. Formal peer mentoring programs matching patients with survivor peers provides emotional and social support. Gynecological cancer patients are: underserved in the survivorship community, stigmatized due to disease, suffer elevated distress. Little is known on how to design and implement a formal peer support program for gynecologic cancer. Methods: To study the effect of peer support, a novel outpatient pilot peer support program for gynecologic cancer patients was implemented. Peer mentors had prior gynecologic cancers, completed treatment 1 year prior, and had formal 6 hour training. Newly diagnosed patients were matched with a peer at: 1) initial diagnosis 2) post-surgery 3) chemotherapy/radiation initiation 4) post treatment. Patients and Peers were matched based upon demographics. Qualitative individual and group interviews were used for program evaluation. Results: To date, 38 participants are enrolled: 17 peer mentors underwent train...


Choosing the Gutzwiller-type variational wave function and using the variational Monte Carlo (VMC) method, we have calculated the ground-state energies of two-dimensional (2D) Hubbard squares at temperature [ital T]=0 and have obtained the phase diagram in the small doping region ([delta]=0--0.15). We do not find the spiral phase until at least [ital U][approx]20 in the half-filled and dilute-doping cases. This is different from the results obtained by C. Jayaprakash [ital et] [ital al]., who calculated the phase diagram of the 2D [ital t]-[ital J] model at temperature [ital T]=0 with the slave-fermion mean-field theory and found the spiral phase at much lower values of [ital U]/[ital t].


It describes the process of forming and structuring the archive of the Toledo Provincial High School, and their evolution to enter the Provincial Historical Archive. Similarly, it suggest a classification table for this documentary.


Abstract : A review of shipboard high frequency direction finding research at Southwest Research Institute is presented for the ten-year period ending in 1965. Problem factors as recognized prior to 1955 are listed with status for 1955 and 1965 given in tabular form. A more detailed description of the progress made in relation to each factor is also given. Proposed changes in the method of conducting future research are listed. Supporting detail for various aspects of the work are provided. (Author)


The efforts to improve gender equity and equality have been taken place for years since the struggle of R.A. Kartini. Up to present, the efforts are still in place, however, not yet gain expected results. Preservation of gender inequality can be reproduced in family, society, as well as in the country. The increasing attention to gender is forced by women conference conducted by the UN. Four paradigms are identified: 1) Women in Develoment (WID) concept that emerging researches on womwn participation in development process; 2) Gender and Development (GAD) concept in which female is related to male; 3) Women's empowerment; 4) Gender Mainstreaming. All of these paradigms have been implemented, but the results are not as expected. This condition reflects the needs of more critical attention in the implementation. For instances by considering women heterogeneity in terms of culture, social, and economis values, and thus it is necessary to take a need assessment in individual and institution levels. Men are also needed to take participation in gender studies to avoid bias. It ia also important to carry out program of education information communication to spread the information about women programs that have been and will be conducted to improve women participation. Also, government commitment is crucial to increase gender sensitivity in public bureaucracy


tag=1 data=New Zealand's electoral reform. by Wayne Mapp

tag=2 data=Mapp, Wayne

tag=3 data=Policy,

tag=4 data=9

tag=5 data=2

tag=6 data=Winter 1993

tag=7 data=6-10.

tag=8 data=VOTING SYSTEMS

tag=10 data=In November 1993 New Zealanders will vote not only in a general election but also in a binding referendum on electoral reform. First past the post, Mixed Member Proportional and an upper house.

tag=11 data=1993/5/8

tag=12 data=93/0456

tag=13 data=CAB


The article features a temporal approach to modelling the social impact of Western colonialism. We collect a data set for all former colonies and dependencies that are regarded as countries today (143 observations). Our data, as well as existing theory, suggest that the very heterogeneous era of colonization might be divided into an early 'mercantilist' wave and a much later 'imperialist' wave with quite different characteristics. We demonstrate that a commonly used determinant of institutional quality - colonial settler mortality - had a much weaker effect on institutional outcomes during the imperialist scramble for Africa. When we broaden the analysis, it is shown that the positive effect of colonial duration on democracy is strongest among countries colonized during the imperialist era. Controlling for colonial duration, our results further indicate that a long history of statehood is bad for democracy while there is almost no effect of the national identity of the colonizer.


To investigate diabetic alterations of small intestinal transit and bacterial growth, we performed hydrogen breath tests (10 g lactulose via duodenal tube at the ligament of Treitz), bacterial cultures, and determinations of unconjugated serum bile acids in 19 patients with long-standing diabetes and 7 healthy controls. Asymptomatic diabetics had a late rise in breath hydrogen, indicating prolonged jejunal-cecal transit (86 ± 10 min, p < 0.05) as an early pathogenic event. Rise in breath hydrogen in symptomatic diabetics (constipation: 50 ± 6 min; diarrhea: 41 ± 11 min) was not significantly different from controls (57 ± 8 min). Bacterial studies and increased unconjugated serum bile acids suggest bacterial overgrowth in some symptomatic diabetics. Bacterial overgrowth was associated more frequently (p < 0.05) with a rise in breath hydrogen before 45 min or after 75 min. Changes in the hydrogen breath test, bacterial growth, or unconjugated serum bile acids did not correlate with gastrointestinal symptoms of diabetes.


This project addresses the issue of how to enhance the interactions between academia and industries in Korea. We will examine the social and historical factors underlying the university-industry linkage as well as the organizational strategies for the R&D networking. The obj ective of the project is to assist better understanding of the current status of university-industry linkages and suggest relevant policy recommendations.Under this proj ect we organized the workshop on university-industry collaboration/networking in Korea. The workshop was held on November 1 at the Asia/Pacific Research Center at Stanford University. Four experts on this issue presented their papers to address the current situation of various aspects of the university-industry networking in Korea. Five discussants from Stanford University responded to these four presentations, especially with a focus on policy suggestions to improve the current state of university-industry networking.The final report consists of the outcomes of the workshop: four papers presented in the workshop and response comments by five discussion panels. The papers are: "Infrastructure of Research and Development and Human Resource in Korea" (Jong-Chun Woo, Seoul National University), "A Study on R&D Human Resources Mobility between Research Institute and Industry, Universities in Korea: the Macro view and Micro Analysis" (Jae-Gu Kim et al., Myongj i University), "Technology Transfers through University-Industry Cooperation: An Overview of Korean Experience" (Kiseok Lee, Kyung Hee University), and "Industry and University Linkage for Development through Technical Human Resource Development in Korea" (Ji Soo Kim, Korea Advanced Institute of Science and Technology). The response comments are made by scholars and practitioners in Silicon Valley: Nathan Rosenberg (Department of Economics, Stanford University), Catherine Ku (Director, Office of Technology Licensing, Stanford University), Rafiq Dossani (Asia/Pacific Research Center, Stanford University), Mariko Yoshihara Yang (Asia/Pacific Research Center, Stanford University), and Michael Paek (Korean American Attorney).


In recent years, e-commerce businesses have seen an increase in the daily volume of packages to be delivered, as well as an increase in the number of particularly demanding customer expectations. In this respect, the delivery mechanism became prohibitively expensive, particularly for the final kilometer. To stay competitive and meet the increased demand, businesses began to look for innovative autonomous delivery options for the last mile, such as autonomous unmanned aerial vehicles/drones, which are a promising alternative for the logistics industry. Following the success of drones in surveillance and remote sensing, drone delivery systems have begun to emerge as a new solution to reduce delivery costs and delivery time. In the coming years, autonomous drone sharing systems will be an unavoidable logistical solution, especially with the new laws/recommendations introduced by the Flight World Organization on how to organize the operations of these special unmanned airline systems. This paper provides a comprehensive literature survey on a set of relevant research issues and highlights the representative solutions and concepts that have been proposed thus far in the design and modeling of the logistics of drone delivery systems, with the purpose of discussing the respective performance levels reached by the various suggested approaches. Furthermore, the paper also investigates the central problems to be addressed and briefly discusses and outlines a series of interesting new research avenues of relevance for drone-based package delivery systems.


In a disaster aftermath in places lacking geospatial preparedness, the United Nations Office for the Coordination of Humanitarian Affairs creates a framework for cooperation with the Coordinated Data Scramble initiative, where Information Management Officers (IMOs) from different organizations work together in supporting the coordination of humanitarian aid. The perspective of these IMOs has been considered to identify the factors influencing the use of GIS in this context. The results show the requirement for a geodata management strategy, including geodata gathering, maintenance, and decision‐making processes based on those geodata. Geodata should be reliable and up‐to‐date. It requires consistent and useful metadata and the possibility of contacting the geodata source. Security and political issues limit information sharing. In this context, OpenStreetMap is often used as a source of information. Therefore, improving OpenStreetMap improves geospatial preparedness. Nevertheless, the use of this open platform highlights issues related to information privacy.


Unexplained pain and weakness, i.e., without obvious predisposing factors, are often encountered by physiatrists and efforts should be made to determine the cause. A 63-year-old male presented with radiating pain in his right arm and mild weakness of the right hand. An electrodiagnostic examination revealed distal symmetric sensory polyneuropathy in the upper and lower extremities, and denervation potentials in the forearm muscles, which were inconsistent with the cervical spine MRI images and symptoms. A predisposing undiscovered disease was revealed, i.e., squamous cell carcinoma in the lung; brain metastasis affecting the left primary motor cortex was also detected. Therefore, we concluded that the pain and weakness were related to paraneoplastic syndrome and brain metastases of the hand knob. The observed denervation potentials were characterized as trans-synaptic changes in the brain metastasis. This case highlights the importance of unexplainable focal pain and weakness in the increasing prevalence of cancer. (Clinical Pain 2019;18:88-91)


A major controversy in cardiac pacemaker therapy is the role of prophylactic temporary or permanent pacing following an acute myocardial infarction. A reason for this is that the physician is dealing with a variahle unpredictable myocardial conduction disorder and a prognosis limiting contraction abnormality with a propensity for further acute infarction. Thus, any attempt to evaluate the effects of pacing will be hampered by the myocardial dysfunction, manifesting as congestive cardiac failure, reduced forward output, angina, arrhythmias and sudden death. The conduction abnormalities that occur with an acute inferior infarction are transient and reversible iand begin as first degree atripventricular block, progressing to second degree atrioventricular block of the Wenckebach type. Further deterioration in atrioventricular conduction results in proximal complete heart block.""'" The junctional pacemaker that emer-


Planar impact experiments of soda-lime glass were conducted on a 57mm diameter one-stage gas gun,in which the free surface particle velocity histories for several different thicknesses of soda-lime glass under the same impact loading were measured by using VISAR(Velocity Interferometer System for Any Reflector).Both the failure wave velocity and the failure wave trajectory were obtained.The experimental results showed that there is a time delay for the failure wave to form on the impact surface of the soda-lime glass,which decreases with the magnitude of the impact load.The present study plays an important role in further understanding of the formation mechanism and propagation law of failure wave in brittle materials.


The article discusses the prospects of population growth, urbanization, and environmental problems that encourage the creation of a new generation of cities with urban infrastructure - «Smart city». The lack of research on this topic in Kazakhstan determines the relevance of the chosen topic. Smart city development is a strategic process that requires innovation in the approach, planning, operation, communication, and management of urban enterprises. Striving to combine economic growth with efficiency, environmental improvement, and positivity. The city of Turkestan has adopted the «Smart City» strategy. Normative ideas about the smart city Achievements in the field of ICT reflect more inclusive, effective, and democratic local government. Creating a smart city affects the formation of the city brand. The article uses statistical and surveys methods. The results of the questionnaire were included in the SPSS 22. The article analyzes the program, the results of normative tests, and factor analysis of the variable elements for the creation of a smart city.


ABSTRACTPurpose: compare the otoacoustic emissions response level and latency in two situations: with and without contralateral competitive noise. Methods: thirty individuals between eighteen and thirty-year-old, with no auditory complaints and presence of otoacoustic distortion product emissions were evaluated. The latency and the response level of otoacoustic emissions was evaluated using the Latencygram program . The test was performed in two different situations: with and without contralateral competitive white noise. Results: the results demonstrated a significant reduction in otoacoustic emissions response levels with contralateral noise, proving the otoacoustic suppression effect associated with olivocochlear efferent system action. However, there was no significant difference in otoacoustic emissions latency. Conclusion: the efferent system may act only in otoacoustic emissions response level modulation but it does not interfere in otoacoustic emissions latency. KEYWORDS: Otoacoustic Emissions, Spontaneous; Reaction Time; Acoustic Estimulation


A procedure that simply and effectively smoothes the contour lines derived from triangular irregular networks [TIN) is presented here. This procedure is shown to use both the TIN and its linearly interpolated contours (raw contours), which puts this process somewhere between the two smoothing approaches currently in use. Hence, the qualification of eclectic. The two approaches currently in use, smoothing of contours one at the time and independently of the others in the contour set, and contouring of smooth patches, are discussed with reference to objections that have been raised because of their shortcomings. The eclectic procedure presented in this paper is described as a simple splicing of arcs of quadratic parabolas, which gives an elegant look to the finished product and ensures that all source data elements are scrupulously honored. Additionally; the procedure is said to minimize the departures of the smoothed contours from the linear model embodied in the TIN. A simple modification to the basic procedure illustrates the manner in which the smoothing effect can be varied at will.


PROBLEM: Decay accelerating factor (DAF) is implicated in protection of cell membrane from toxicity of complement. In this study, we investigated a hypothesis that DAF is up‐regulated in the endometrial adenocarcinoma, which could increase potential of malignant cells to escape destruction by complement.
METHODS: DAF density was evaluated in endometrial biopsies of patients with adenocarcinoma at various stages and compared with ten endometrial biopsies from non‐malignant patients at the proliferative phase.
RESULTS: DAF expression in normal proliferative endometrium varied between 1 and 30%. While DAF density in patients with stage I cancer was in the range 56–98% (mean 78%), stage III values varied from 28 to 16% (mean 21%), P<0.05. DAF density in the well‐differentiated Ishikawa cell line was two‐fold higher than in metastatic cell line AN3CA.
CONCLUSIONS: Our findings are consistent with a hypothesis that endometrial adenocarcinoma of early stage that is exposed to complement attack may up‐regulate DAF to protect malignant cells from complement lysis.


Abstract In this article, we tackle the problem of using globally optimal estimate for variational surface reconstruction. We give an overview of globally optimal method on variational surface when the three-dimensional (3D) surface is represented by a point-based surface and a triangular mesh-based surface, and we detail the variational surface used on surface reconstruction. It can be applied to derive a range of meaningful surface reconstructions from this high dimensional space. We show that using a progression of spatially varying anisotropic weights can achieve significant improvements in surface reconstruction. Simulated surfaces and real model are experimentally studied, and the results validate that the proposed approaches improved the reconstruction. The proposed method improved the reconstruction results significantly for the simulated and real data.


Packet Tracer is a comprehensive instructional software application for teaching skills and concepts associated with computer networking. In addition to a wide range of simulation, visualization, and micro-world authoring features to support student-centered Exploration, Explanation and Experimentation, Packet Tracer includes features for assessment task authoring with automated scoring and reporting. This paper provides a theoretical explanation for these features following the approach of Evidence Centered Design (ECD) and discusses implications for future extension. It is argued that the four process model for assessment delivery provides a number of valuable features that allow for conceptual and computational extension into improved simulation-based assessment, as well as gaming and tutoring.


The colors of Au nanoparticles (Au NPs) change along with conformational changes in cytochrome c (Cyt c). We exploited this property for the colorimetric detection of Cyt c conformational changes induced by H + and L鄄 cysteine (L鄄Cys). We improved the conventional procedure for this detection. After the addition of Cyt c within different pH values, the Au NPs are either cyan, blue, purple or red. This indicates that the Au NPs can be applied to the rapid colorimetric detection of pH鄄induced conformational changes in Cyt c. At pH 7 the color of Au NPs changes from purple to blue and then cyan upon the addition of L鄄Cys, which suggests that the Au NPs can be used for the colorimetric detection of Cyt c conformational changes caused by interaction with L鄄Cys. The conformational changes of Cyt c were verified by circular dichroism (CD) spectroscopy. The relationship between the aggregation states and colors of the Au NPs after the addition of Cyt c was characterized by UV鄄Vis absorption spectroscopy and scanning electron microscopy (SEM).


An ultrastructural study of motile cell development in the green alga Trentepohlia aurea has revealed the presence of multilayered structures (MLS) associated With flagellar bases. These MLS are ultrastructurally similar to MLS described in pteridophyte and bryophyte sperm and in the zoospore of the green algae Coleochaete and Klebsormidium. However, 2 MLS are found in each biflagellate motile cell of T. aurea, while other previously described MLS occur singly in biflagellate motile cells. In addition, the MLS of T. aurea consist of fewer microtubules and are structurally simpler than most other MLS described. The MLS of Trentepohlia may represent a stage in the evolutionary development of the MLS of land plants. The presence or absence of the MLS in motile cells of green algae may be a useful character in phylogenetic studies.


The Society of Nuclear Medicine and Molecular Imaging (SNMMI) is an international scientific and professional organization founded in 1954 to promote the science, technology, and practical application of nuclear medicine. Its 18,000 members are physicians, technologists, and scientists specializing in the research and practice of nuclear medicine. In addition to publishing journals, newsletters, and books, the SNMMI also sponsors international meetings and workshops designed to increase the competencies of nuclear medicine practitioners and to promote new advances in the science of nuclear medicine. The European Association of Nuclear Medicine (EANM) is a professional nonprofit medical association that facilitates communication worldwide between individuals pursuing clinical and research excellence in nuclear medicine. The EANM was founded in 1985. The SNMMI/EANM will periodically define new guidelines for nuclear medicine practice to help advance the science of nuclear medicine and to improve the quality of service to patients. Existing practice guidelines will be reviewed for revision or renewal, as appropriate, on their fifth anniversary or sooner, if indicated. Each practice guideline, representing a policy statement by the SNMMI/EANM, has undergone a thorough consensus process in which it has been subjected to extensive review. The SNMMI/EANM recognizes that the safe and effective use of diagnostic nuclear medicine imaging requires specific training, skills, and techniques, as described in each document. The EANM and SNMMI have written and approved these guidelines to promote the use of nuclear medicine procedures with high quality. These guidelines are intended to assist practitioners in providing appropriate nuclear medicine care for patients. They are not inflexible rules or requirements of practice and are not intended, nor should they be used, to establish a legal standard of care. For these reasons and those set forth below, the SNMMI/ EANM cautions against the use of these guidelines in litigation in which the clinical decisions of a practitioner are called into question. The ultimate judgment regarding the propriety of any specific procedure or course of action must be made by medical professionals taking into account the unique circumstances of each case. Thus, there is no implication that an approach differing from the guidelines, standing alone, is below the standard of care. To the contrary, a conscientious practitioner may responsibly adopt a course of action different from that set forth in the guidelines when, in the reasonable judgment of the practitioner, such course of action is indicated by the condition of the patient, limitations of available resources, or advances in knowledge or technology subsequent to publication of the guidelines. The practice of medicine involves not only the science but also the art of dealing with the prevention, diagnosis, alleviation, and treatment of disease. The variety and complexity of human conditions make it impossible to always reach the most appropriate diagnosis or to predict with certainty a particular response to treatment. Therefore, it should be recognized that adherence to these guidelines will not ensure an accurate diagnosis or a successful outcome. All that should be expected is that the practitioner will follow a reasonable course of action based on current knowledge, available resources, and the needs of the patient to deliver effective and safe medical care. The sole purpose of these guidelines is to assist practitioners in achieving this objective.


This work addresses the problem of new forms of individuation and the novel types of addictions that these entail. When the work of thinking becomes dangerous in adolescence, some current technologies can influence it by manipulating the adolescentas attention in order to reduce anxiety.


The use of groups has become an integral part of management education as a mechanism to help students learn through interaction with others as well as to become accustomed to working in a group environment that emulates the work place. The present study examined the amountof time spentworkingas a group and individuals 'attitudes toward work ingroups, and how these may affect academic performance. Both the time involved in group work and attitudes toward group work explained significant amounts of variance in grade point average (GPA) beyond that due to background variables such as previous grade point average, standardized test scores, and work experience. Exploratory analyses using aggregate group GPA measure revealed differences in attitudes toward group work between high-performing and low-performing groups, with time involved in group work as the main predictor of group GPA.


A 50-day feeding trial was conducted to investigate supplemental effects of blue mussel (BM) when fed low fishmeal (FM) diets for juvenile tiger puffer. Isonitrogenous FM and soybean protein isolate (SPI) based diets, containing five different level of BM (0, 2.7, 5.3, 8.1, 10.5%) were formulated. A control diet contained 63% of FM without SPI. Nine juveniles (27.01±0.05 g) were randomly stocked into 100 l tank and fed the test diet twice a day with satiation. Results indicated that a diet containing 27% FM, 27% SPI together with 5.3% BM produced the highest weight gain, feed intake, specific growth rate and feed efficiency, and the values of those parameters were not significantly different (P>0.05) from those of a control group and a diet containing 28.5% FM, 27% SPI together with 2.7% BM. No significant differences were detected in survival rate, hepatosomatic index, and chemical compositions of fish whole body among all treatments. This study demonstrated that BM supplementation in low FM diet was very effective to improve the growth of tiger puffer, and level of 2.7 to 5.3% was optimum when 27% of SPI together with FM ranging from 27 to 28.5% were used.


We must construct excellent subject and researchtype college in order to found a research-type university.In this article,took Wuhan University as an example,we put for ward the promoting tatics of subject construction in founding a research-type university.


As an alternative to bulk processing of high-{Tc} materials for conductor applications, we have been studying the applicability of physical vapor deposition to the problem of developing flexible superconducting elements with high I{sub c}. Specifically, we have used a two-step process consisting of ion-assisted sputtering of textured buffer layers on nickel-based substrates, followed by pulsed laser deposition of YBaCu{sub 3}O{sub 7-{delta}} (YBCO) films. The films have been analyzed by measuring the J{sub c} of microbridges, I{sub c} for 1 cm-wide strips, and field dependence up to 9 T. In addition tests have been conducted to determine minimum bending radius of the films.


Photochemical cycloaddition reactions in anellated oxanorbornadiene derivatives have been investigated. In the case of 7a the tetracyclic isomer 8a can be isolated which adds dimethylacetylenedicarboxylate in the manner of a bis-homo-furan system. On thermal activation 8a yields the thiepino-oxepin derivative 9a. In contrast, on direct photoexcitation of the benzoxanorbornadiene the primary photoproduct cannot be identified, the reaction leading directly to the benz[d]oxepin.


Site managers need to be kept abreast of the challenges of ever–changing construction technology, knowledge ideology, management techniques, dynamic nature of construction site works and this requires training and retraining. The aim of this paper is to examine and evaluate the specific training needs of construction site managers handling selected construction projects in Lagos State of Nigeria. A structured questionnaire survey was used to collect information on construction site managers in Lagos State. The data were analysed using descriptive statistics, mean score, weighted average, and t-test distribution. The result of the study revealed that there is common agreement that training of site managers should address human and industrial relations, building production and project management, then communication skills and computing. The paper concludes with recommendation to establish training institutes to take up the managerial training addressing the skill shortages of site managers to enhance efficiency in the construction industry. Field visit with site managers on weekend basis should be considered as the most effective method of training.


Quantitative analysis of chemical and biochemical molecules is an important requirement in many biochemical assays and can be a challenging task in microfluidic systems due to the smaller sample volumes. In the present study, we report on the detection and quantification of nucleic acid samples contained in nanoliter (nL) and picoliter (pL) droplets, formed by employing a DEP based surface microfluidic system. This surface microfluidic system utilizes non-uniform AC electric fields for dispensing multiple, nanoliter (and picoliter) sized aliquots of samples and reagents, which can furthermore be individually addressed, transported and mixed on-chip in a controlled and parallel fashion. Quantification of dsDNA samples is carried out using a fluorescence based Quant-IT PicoGreen assay, performed on the surface microfluidic chip, while the low-level fluorescence emissions are quantified using a photo-multiplier tube. Our findings show that sample DNA concentrations remain uniform across the dispensed droplets, although the volume of droplets can be varied as per requirements. Experimental results furthermore prove that our DEP based and electric field assisted on-chip mixing methodology is at par with conventional mixing strategies such as vortexing, stirring etc. and more readily achieved compared to conventional closed channel microfluidic systems.


In order a hotel business to achieve a long-term quality performance, it should train, empower and actively involve the employees in the service process. Therefore, the involvement of Human Resourse Management (HRM) department is imperative. The purpose of this study is to explore the level that HRM basic approaches are applied by hotels, particularly those fundamental requirements that might enhance quality service provision. Furthermore, the paper is examining the individual and unique characteristics of the hotel units, such as size, categorization etc., in an effort to reveal possible diversions and correlations according to the HRM implemented philosophy. According to the research findings, the examined hotels adopt a range of agreed HR policies and practices that are more likely to create organizations aiming to compete on the basis of high-quality services. Moreover, the hotels that apply greater HRM principles are those of great capacity. This can be explained due to the large number of hotel employees; their number, along with the fact that hospitality is a labour-intensive industry, necessitates HRM practices to play an important role in service quality provision. One more interesting finding arising from this research is that the category of the hotel does not play an important role at the degree that a hotel applies HRM best practices.


Abstract : Technology Identification, Due Diligence, Risk Management, Insertion, Integration, Collaboration and Planning processes are on-going, and cover complete life cycle of a System-of-Systems (SoS) or System. DoDI 5000.2 states that... "...The purpose is ...to reduce technology risk and to determine appropriate set of technologies to be integrated into a full system. Technology Development is a continuous technology discovery and development process reflecting close collaboration between the S&T community, the user, and the system developer. It is an iterative process designed to assess the viability of technologies while simultaneously refining user requirement"...


This paper presents the use of Finite Element Method for heat transfer analysis. Connections wall-beam-floor structures with different positions of the thermal insulation have been analyzed and conclusions about energy efficiency and energy loss are made. Keywords : heat transfer, numerical analysis, finite elements, thermal insulation, energy efficiency.


Dung from breeding farm was widely used as fertility in farmland.However,superfluous dung would cumulate in the farmland and turn into latent contamination to surface water and ground water.Therefore,it is significant to ascertain the reasonable quantity of dung fertilized on the farmland.In this paper,a swine breeding farm was studied to discuss the phosphorus balance of manure and farmland load.Three aspects were considered in the phosphorus balance.1) The phosphorus imputes from dung,straw manure,atmospheric deposition,and seed.2) The phosphorus output by crop harvest,eluviating and corrading.3) Reasonable residual phosphorus.Results show that the proper phosphorus load of farmland was 46.45 kg /( hm2·yr),and 50.48 hm2farmland were needed to receive all the dung from the swine breeding farm.This study provides a feasible means to estimate the balance between farmland and breeding farm.


Transportation is the lifeline of economic development,high-grade highway with its fast,convenient mode of transportation impact on the country′s economic,social and cultural development.In recent years,as our highway network construction with the rapid development,the demand for network monitoring has been driven by road network construction,the demand for network monitoring has also gradually risen to a key position.The traditional tree model in network traffic moni-toring mode to monitor the emergence of many new problems.This article provides a new kind of network monitoring model for the network monitoring,thus better provides high-quality,high efficient management,and travel information services for the traffic network(especially highway).


This numerical study seeks to find a feasible location and orientation for a piezoelectric material to actuate a solid-state ornithopter modelled after the Great Blue Heron. The analysis is first conducted statically and dynamically on a simple rectangular cantilevered plate. A separate simplified model of a plate with Great Blue Heron wing profile is also examined statically and dynamically. The parameters considered are the angles of two piezoelectric Macro-Fiber Composite patches that are adhered to the cantilevered substrate near its base and at mid-span. The orientations of the patches are swept from 0 to 180 degrees as they are actuated at amplitude of 1000 Volts either statically or harmonically. By varying the orientation angles, various bending and twisting deflections are obtained and the responses are analyzed.Copyright © 2014 by ASME


The effect of reduced iron powder on the performance of functional mortar was studied. Aimed at the construction performance, the experiments of consistency and water retention were carried out. Aimed at the mechanical properties, tensile bond strength, compressive strength and flexural strength experiment were carried out. The results show that the content of powder has little effect on mortar consistency. It can improve water retention. The 14d tensile bond strength is 36.2% higher than the reference mortar, which can meet the requirements of plaster-mortar. The compressive strength of 7d mortar was 24.2% higher than that of reference mortar. Compared with the reference mortar, the 28d compressive strength increased 13.6%, the 7d flexural strength increased 36.6%, and the 28d increased 25.8%.


Quantum beats in the recombination fluorescence of 1,2,3,4-tetraphenylcyclopenta-1,3-diene and 2,3,4,5-tetraphenyl-1-germacyclopenta-2,4-diene radical anions have been detected and the hfc constants in these species determined.


Lab-based experiments and observational data have consistently shown that extraverted behavior is associated with elevated levels of positive affect. This association typically holds regardless of one's dispositional level of trait extraversion, and individuals who enact extraverted behaviors in laboratory settings do not demonstrate costs associated with acting counter-dispositionally. Inspired by these findings, we sought to test the efficacy of week-long 'enacted extraversion' interventions. In three studies, participants engaged in fifteen minutes of assigned behaviors in their daily life for five consecutive days. Studies 1 and 2 compared the effect of adding more introverted or extraverted behavior (or a control task). Study 3 compared the effect of adding social extraverted behavior or non-social extraverted behavior (or a control task). We assessed positive affect and several indicators of well-being during pretest (day 1) and post-test (day 7), as well as 'in-the-moment' (days 2-6). Participants who engaged in extraverted behavior reported greater levels of positive affect 'in-the-moment' when compared to introverted and control behaviors. We did not observe strong evidence to suggest that this effect was more pronounced for dispositional extraverts. The current research explores the effects of extraverted behavior on other indicators of well-being and examines the effectiveness of acting extraverted (both socially and non-socially) as a well-being strategy.


Short circuit disturbance in the electric power system, is the relationship between one voltage system and another directly connected system with a very small impedance. The direct connection results in the distribution of electric current at the fault point exceeding the nominal current. This situation has an impact on system instability, the system works in an unbalanced state and can damage equipment, if the disturbance is not neutralized (secured). The study of short circuit faults fundamentally consists of symmetrical faults and unsymmetrical faults (line to Ground Fault). In the simulation study, it is observed that three-phase symmetrical faults can be analyzed based on parametric data of the sub-switch reactance of the system, and one-phase asymmetrical faults to ground. Symmetrical fault analysis can be used as a reference in determining the breaker capacity, while for asymmetrical faults, L-G faults are implemented in determining the protection relay settings. The determination of the value of symmetrical and asymmetrical faults applies the analytical method of the Zbus model, carried out with system impedance data from the line diagram of the electric power system, then the system reactance data entry is carried out, then the symbolic notation of the connecting points is referred to as Bus. The number of buses will determine the number of orders of the bus impedance matrix (ZBUS). This ZBUS matrix becomes a reference in determining the value of short circuit impedance on each bus, by observing the diagonal of the ZBUS matrix. Calculations using the Matlab software tool, to determine the amount of fault current for each bus. From the data of 14 BUS-IEEE Power Systems, a trial was carried out for the fundamental study of the largest analysis results on buses 2, and from the characteristics of the comparison results, it can be seen that the value of the symmetrical fault current is greater than that of the non-symmetrical fault.


Field experiments for resistance of major commercial Eucalyptus spp.varieties in south Guangxi including Eucalyptus urophylla × E.grandis DH32-26,DH33-27,DH32-28,DH32-29,Eucalyptus grandis × E.urophylla GL9 against Leptocybe invasa Fisher La Salle were conducted in the insect infected areas in Ningming,Guangxi,from April 2009 to August 2010.The results indicated that DH32-26 and DH32-28 showed high resistance against L.invasa which can be selected to be the cultivar for planting.And proper field,better fostering and fertilizing can improve the resistance against L.invasa.


: This paper is an attempt to distinguish depressed patients from healthy samples mainly by analyzing magnetoencephalogram data of depressed patients and healthy people under different emotional picture stimuli. The following conclusions are mainly drawn: First, the relationship of information storage and condition entropy is obtained firstly through the formula derivation, and the higher the information storage value, the lower the condition entropy. The healthier the biological system, the higher the complexity. Second, the conditional entropy values of the magnetoencephalography channel were mostly higher in the healthy samples than in the depressed patients under the emotional picture stimulation. Accordingly, the conditional entropy values of the frontal region under negative stimulation were lower in depressed patients than in healthy subjects. Third, under both the AR model and the ARFI model, the magnetoencephalogram information storage values were higher in depressed patients than in healthy samples. The difference was more pronounced especially near the frontal regions for both. The variability of the results obtained under the ARFI model was even more pronounced when depressed patients and healthy samples were more discriminated near the left frontal region than the right frontal region, as revealed by the study of line plots of information storage values across left and right frontal regions channels.


ABSTRACT Before a cross-border merger can be completed, it must be sanctioned by the designated authority in the transferee Member State. Uncertainty has arisen as to the proper test for the English court to apply at this stage. This article argues that the approach from Re Diamond Resorts Plc, involving a intensive scrutiny of the benefits and disbenefits to stakeholders, does not represent the proper approach under the Cross-Border Merger Directive.


In this study, we employ a diff erence-in-diff erence, gravity-equation approach to quantifying the trade impact of hightechnology export controls that are motivated by national security. We estimate the eff ect of controls on high-tech export performance of the United States, of its traditional rival (peer) exporters, and of emerging exporters. Using an 11-year panel of seven high-tech sectors from 1994 through 2004, we find that the United States under-exports to "high-threat" importers. We find, more surprisingly, that the United States over-exports to "medium-threat" importers and to a large "trusted" group of importers, both relative to a norm (default group) of importers. We find that traditional peer exporters under-export to the trusted group of importers, and along with emerging exporters, under-export to most medium-threat importers. Th ese findings, robust in a comparable dataset ending in 2011, suggest high substitutability between export suppliers and export markets for high-tech products. Th e same peer exporters over-export to high-threat importers, suggesting their less stringent enforcement of multilateral export controls and also undermining to a certain extent, the security objective of the very strictest of these controls. Overall, importers deemed security threats import only half of their high-tech potential from the 10 exporters on which we focus. Our study underlines the importance of current American eff orts to reform the export control regime to make it more target-eff ective.


Malaysia's glass industry has grown from humble beginnings thirty years ago to becoming a high technology exporter especially for the electronic and automotive industries. This article reviews the country's growing glass industry and looks at the major companies involved in its expansion.


This research is aimed at empirically proofing the pecking order theory. Additionally, it is specifically focused on investigating the influence of assets tangibility, firm size, growth, and profitability variables to leverage, in clarifying the decision making process among the companies within the Indonesian stock market. Those variables have significant correlations with various assumptions in pecking order theory. The data used in this research are financial ratios gathered from 99 sample companies during the period of 2002 to 2007. This research applied the multiple regression method by using debt ratio as the fixed variable; and profitability, growth and firm size as the free variables. The result shows that there is an indication of pecking order theory contribution in the financial decisions process among the companies within the Indonesian stock market.


Some Reflections Becoming a vocational agriculture teacher in Colorado many years ago was not my first choice; but it certainly turned out to be my best choice. Throughout my 34 years as an agricultural educator at the high school and university levels, three philosophical thoughts about teaching and learning were and still are ingrained in my memory. I vigorously employed these tenets in my teaching: What was I attempting to achieve with my teaching? How could I best accomplish what I was trying to achieve? What principles of leaning would help me do it most effectively? Educational Outcomes As a teacher I aggressively championed the idea that for students (secondary and university) to be successful, productive, socially mature, and spiritually happy, they needed to learn how to (1) think, (2) reason logically, and (3) make decisions intelligently. If mastered, their acquired education would make a significant difference in their lives. These three behaviors would contribute to the wealth of the individual and the prosperity of this Nation. It would make their education function in their lives. Needless to say, I reminded my students constantly of the real value of their education. Delivery System Some of the happiest, most satisfying and productive days of my professional life were as a vocational agriculture teacher. I can still envision the vocational agriculture program at Berthoud High School and how proud I was of the achievements of my students and the accomplishments of my teaching. There was a strong FFA chapter with maximum student participation to motivate and involve them in developing leadership and human relations competencies (knowledge, skills, and attitudes). Competency development in agricultural mechanics was a viable and implied component of the overall instruction program. Supervised occupational experience was a unique and significant feature for each and every student. These experiences were occupationally oriented stressing the application of approved practices based upon agricultural science principles and leadership competencies studied in the classroom and laboratory. These planned experiences were also used to identify, in part, curriculum content taught in the classroom. Competency-based instruction stressed the application of agricultural science principles and leadership abilities associated with the agricultural mechanics, supervised occupational experience, and leadership development content of the curriculum. These four components were coupled with and reinforced by strong and enthusiastic parental involvement and support, especially for the FFA and supervised occupational experience segments of the total program. A viable community-based approach which contributed to the agricultural needs of the community completed this delivery system. The net result was a total and balanced delivery system which served the needs of youth and adults who wanted and could benefit from such instruction in this rural school district. Principles of Learning How do people learn? What influences how people involve themselves in the teaching-learning process? The teaching-learning process is nothing more than a series of actions and interactions between the teacher and the learner designed to change the behavior of people, hopefully in a positive way. There are numerous theories on how people learn best. The fundamental truths I utilized every time I planned and delivered (and evaluated) an educational experience or incident were that students learn more and better when: (1) there is interest, (2) needs are being satisfied, (3) thinking is stimulated, (4) students participate actively, (5) two or more senses are used, and (6) a positive climate of success is maintained. Just think of the many teaching activities and strategies a teacher could utilize to apply these principles as they influence how people learn. Of more consequence, visualize how the desired educational outcomes, the delivery system employed, and the principles of learning supplement and compliment each other. …


The intestinal barrier controls intestinal permeability, and its disruption has been associated with multiple diseases. Therefore, preclinical safety biomarkers monitoring barrier integrity are essential during the development of drugs targeting the intestines, particularly if starting treatment early after onset of disease. Classical toxicology endpoints are not sensitive enough and therefore our objective was to identify non‐invasive markers enabling early in vivo detection of colonic barrier perturbation. Male Sprague–Dawley rats were dosed intracolonically via the rectum, using sodium caprate or ibuprofen as tool compounds to alter barrier integrity. Several potentially translational biomarkers and probe molecules related to permeability, inflammation or tissue damage were evaluated, using various analytical platforms, including immunoassays, targeted metabolomics and highly sensitive ultra‐performance liquid chromatography–tandem mass spectrometry. Several markers were identified that allow early in vivo detection of colonic barrier integrity changes, before histopathological evidence of tissue damage. The most promising permeability markers identified were plasma fluorescein isothiocyanate‐dextran 4000 and a lactulose/mannitol/sucralose mixture in urine. These markers showed maximum increases over 100‐fold or approximately 10–50‐fold, respectively. Intracolonic administration of the above probe molecules outperformed oral administration and inflammatory or other biomarkers, such as α2‐macroglobulin, calprotectin, cytokines, prostaglandins and a panel of metabolic molecules to identify early and subtle changes in barrier integrity. However, optimal timing of probe administration and sample collection is important for all markers evaluated. Inclusion of these probe molecules in preclinical toxicity studies might aid in risk assessment and the design of a clinical biomarker plan, as several of these markers have translational potential.


One decade after their introduction into wireless applications, digital fractional-N phase-locked loops are becoming a competitive solution for products. Their ultimate level of spurs is often bounded by the resolution and the linearity of the time-to-digital converter. Although methods for mitigating its nonlinearity have been proven effective in lowering spurs, they typically increase the level of random noise. By contrast, digital-PLL architectures based on digital-to-time converters enable nonlinearity cancellation and spur reduction with no penalty on noise level, while reducing design complexity and power consumption.


In France,only the State can expropriate land from individuals for public interest and the public purpose should be judged by the administrative judges according to the final judicial principle.The Supreme Administrative Court formed a comparative analysis of profit and loss theory in its long-term trial practice.Adopting the theory strengthened the judicial review of land expropriation's public purpose declaration behaviour,ie.judicial review of administrative discretionary right.Meanwhile it still provides enough discretionary space for administrative agencies to choose among different legal schemes.


: Pushing and gripping forces may contribute to Hand-Arm Vibration Syndrome but, thus far, have not been taken into account in vibratory dose assessment according to the current standards. To obtain a better understanding of the symptom onset, we developed a finite element model of the hand to replicate its vibratory behaviour in gripping and pushing actions. In a case study, Supersonic Shear Imaging measurements revealed the significant dependence of muscle stiffness and anisotropy on gripping. The use of these measurements in our model showed that muscle activation influences the driving-point mechanical impedance of the hand and local vibration propagation.


The present study on the vulnerabilities that concern The Internet of Things technology was carried out in order to identify which flaws are present in ubiquitous computing devices in the national scenario, attaching evidence that was found when using the search engines Shodan and Censys, which act on the web in order to find security flaws that are evident. After verification, a document was developed in the form web format, with the evidence found, using questions that instigate the interviewee about the knowledge he has about the failures found, whether he has any practice to protect his devices that are connected to the network and if it occurred to have experienced some experience of data theft or invasion of their devices. Thus, with quantitative data collected in both surveys, we can have a survey of how the deficiency of the security practice affects the defense of devices that are part of the Internet of Things.


Composition of cloud liquid water and interstitial air is reported for aircraft measurements near Charleston, South Carolina, in February 1982. Cloud water was collected by means of a slotted-rod impactor. Cloud-free interstitial air was obtained by a centrifugal separator. Principal ionic species in cloudwater were H/sup +/, SO/sub 4//sup -/, NO/sub 3//sup -/, and NH/sub 4//sup +/. The relative acidity of cloudwater, as measured by the ratio of H/sup +/ to NH/sub 4//sup +/, was much greater than that of the interstitial aerosol or of clear-air aerosol samples. Gaseous O/sub 3/, NO/sub 3/ (i.e., NO+NO/sub 2/), and SO/sub 2/ were present in interstitial air within clouds, whereas HNO/sub 3/ an NH/sub 3/ were below limit of detection (0.4 ppb for both species). Comparision of relative acidity of cloudwater samples with that of clear-air samples suggests that clear-air aerosol and HNO/sub 3/ are incapable of providing the levels of acidity observed in cloudwater. Such acidity would be consistent with in-cloud conversion of prevailing concentrations of SO/sub 2/ or SO/sub 2/+NO/sub 4/ to aqueous strong acid, although other hypotheses cannot be excluded. Comparison of absolute concentrations of cloudwater constituents to concentration in clear-air measurements gives no indication of accumulation of sulfur andmore » nitrogen species by clouds.« less


Loading device for dies, particularly for loading dies in a die cutting machine, comprising two handles (6) are fixed directly to die and which are governed by pneumatic or electric actuators operated remotely by a button on the handles themselves (6), so that the die can be handled easily (can move vertically and rotate on itself in a plane perpendicular to the ground and parallel to the longitudinal axis of the cylinder die shoe (10). thus, the placement of dies in facilitating a punching machine while reducing the execution time of the load operation of the die, particularly when the die has dimensions and considerable weight.


Objective To explore the clinical effect of mifepristone in treating endometriosis. Methods Thirty-six cases of endometriosis were treated with mifepristone orally(12. 5 mg/d after supper everyday) for 3 monthes. Before and after treatment,the size of uterus and the cyst of endometriosis were measured and the levels of liver function, follicle stimulating hormone (FSH), luteining hormone, lactogen, estrogen, pro-gestin, androgen were detected. Results During treatment the symptoms of amenia and menalgia disappeared, the size of cysts reduced (P 0. 05), while the indexes of sexual hormones changed little. Conclusion Mifepriston if effective to treat endometriosis with little side effect. The dosage of 12.5 mg/d is worth recommending for conservative treatment.


This case study explores the second language literacy practices of two Chinese graduate students studying at a Southeastern U.S. university. The findings of this study reveal that technology (technology and computer interchangeable in this paper) and multimedia can foster these two Chinese students" English learning and literacies development and further facilitate their identity negotiation. In addition, the marriage of funds of knowledge with technologies not only boosts these students" English learning confidence, but also helps them accumulate linguistic and cultural capital (Bourdieu, 1986). This empirical research used interviews and semi-structured interviews, classroom observations, and documents to collect data. The first section of this paper discusses L2 literacy and the influences of computer-assisted language learning (CALL) and multiple modes mediated communication on L2 learning and literacy. The second section of this paper analyzes the data derived from the interviews, field notes, and documents. The last section of this paper addresses the implications for second language teaching and learning, which emphasizes the intertwined relationships among multimodality, language, and identity. The implications of this research might provide new insights into second language literacy development and support English instructors to meet the needs of second language learners in the context of the increased population of Chinese students.


Introduction Following recovery from an attack of Newcastle disease the bird is highly immune to the disease. Serum of such birds contains considerable amounts of free antibody, which can be demonstrated by means of a hemagglutination-inhibition test. In studying the development of immunity to Newcastle disease it is of interesest to determine, if possible, whether any tissue antibodies independent of those circulating in the blood stream are developed. In this connection it also seemed desirable to compare adsorption capacity of normal chicken tissues and the neutralizing action of antibodies which are present in the tissue extracts. Methods Chickens of about four to six weeks of age which had recently survived an attack of Newcasle disease in an outbreak in which the mortality was over 80 percent, were used in these experiments. All the birds examined had high titer sera and all still showed symptoms of encephalitis, although they were eating well and otherwise appeared to be normal. The birds were killed by decapitation with a pair of heavy shears. The skin was removed and the following tissues obtained: thigh muscle, breast muscle, liver, kidney, lungs, brain, spleen, bone marrow, peripheral nerves (ischiadic), and blood serum. In each instance the tissues from two birds were freed of excessive moisture, pooled and weighed as soon as possible. The tissues were then ground in a mortar with ten times their weight of physiological saline of pH 7.2 and a small amount of washed quartz sand. This suspension was centrifuged for 15 minutes at 3000 r.p.m. to sediment all cells, and the supernatant fluid was removed and considered as a 10 percent extract of the tissue. The 1-10 diluted extracts contained so much antibody that agglutination was inhibited in all tubes, hence such further dilution was made as found necessary. Most tests were run with 1-10 dilutions of the tissue extracts.


(57) Abstract: Method for the polymer to corona treatment is described. The method nitrogen and hydrogen, ammonia, and the fluoropolymer in an atmosphere containing another and about 0.01 to about 10% by volume gas is selected from the group consisting of a mixture thereof, from the group consisting of polycarbonate and polyimide at least one surface of an article comprising a polymeric material selected comprises exposing the corona discharge.


Molecules in the crystal are connected along the c-axis direction by C—Br⋯π interactions, resulting in zigzag chains parallel to the (010) plane. C—H⋯N and C—H⋯O hydrogen-bonding interactions further connect the molecules, forming a three-dimensional network and reinforcing the molecular packing.


This paper introduces interactive multi-view contents authoring system based on MPEG-4. The MPEG-4 standard, which aims to provide an object based audiovisual coding tool, has been developed to address the emerging needs from communications, interactive broadcasting as well as from mixed service models resulting from technological convergence. Due to the feature of object based coding, it has been considered that MPEG-4 is the most suitable for interactive broadcasting content production. This feature is suitable for creation of the content which provides multiple views of object or scene in interactive manner. In this paper, we categorize the multi-view visual content into two types: panoramic multi-view content and object multi-view content. And design and implementation of the authoring system for interactive multi-view contents is presented. We believe that the proposed method can be effectively used for further deployment of MPEG-4 content to various interactive applications.


Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a brainstem relapsing-remitting inflammatory disease. To date, no treatment besides corticosteroids has been shown to be effective to treat relapses. We report a patient with CLIPPERS initially misdiagnosed with CNS tuberculosis who presented with brainstem attacks responsive to antituberculous therapy.


Voltage fluctuation and possibility of frequent disruptions are usually situations associated with electrical network. The same situation could be prominent while it is dealt with renewable energy sources (wind power, solar energy etc). Because of their intermittent in irradiance of solar energy and inconsistent wind flow, the generated voltage at load is also fluctuating in nature. Since the electrical appliances connected to load side are sensitive to voltage, so it requires the voltage needs to be regulated because of sensitivity of load devices. In this paper, a fast PWM-based Smart Series Reactive Voltage Compensator (SSRVC) has been modelled and simulated under a Sliding-Mode Controller (SMC) to investigate its performance and the relevant results are presented.


Five novel coordination polymers, [(Cu(L1)2OH)·Cl·3H2O] (1) [L1 = bis(N-imidazolyl)methane], [Cd(L1)2(NCS)2] (2), [Zn(L1)2(NCS)2] (3), [Cu(L1)2(NO3)2] (4), and [Cu(L2)1.5(NCS)2] (5) [L2 = 1,4-bis(N-imidazolyl)butane] were obtained from self-assembly of the corresponding metal salts with flexible ligands and their structures were fully characterized by X-ray diffraction (XRD) analysis, Fourier Transform Infrared (FT-IR) spectroscopy, elemental analysis and thermogravimetric (TGA) measurements. X-ray diffraction analyses revealed that complexes 1, 2, 3, and 4 exhibit 1D double-stranded chain structures, which result from doubly bridged [CuOH], [M(NCS)2] (M = Cd, Zn), and [Cu(NO3)2] units, respectively. The polymeric copper complex 5 displays 1D ladder structure., These complexes, with the exception of complex 1, are stable up to 300 °C.


We report on the fabrication and characterization of high efficiency ultraviolet (UV) light emitting diodes (LEDs) with emission wavelength ranging from 255 to 355 nm. Epi‐layers of UV LEDs were grown on AlGaN templates with sapphire substrates. Flip‐chip configuration without removing sapphire is used for characterization of the UV LEDs. External quantum efficiencies (EQEs) over 3% were obtained for all the investigated wavelengths with maximum value reaching 5.1% for 280 nm LED. Under RT DC operation at a current of 500 mA, output powers of 38, 77, and 64 mW were measured for 257, 280, and 354 nm, respectively. By using enhanced light extraction technologies, such as, moth‐eye structure on the back side of the sapphire substrate, we expect to improve these values by up to 50%.


................................................................................................................................ ii Preface .................................................................................................................................. iv Table of contents ................................................................................................................... v List of tables ....................................................................................................................... viii List of figures ....................................................................................................................... ix List of abbreviations ............................................................................................................ xi Acknowledgements ............................................................................................................ xiii CHAPTER ONE: Introduction ........................................................................................... 1 1.1 Animal morphogenesis .............................................................................................. 1 1.2 Cell adhesion and morphogenesis ............................................................................ 2 1.2.1 Cell adhesion is required for morphogenesis. ...................................................... 2 1.2.2 The Integrin-mediated adhesion during morphogenesis. ..................................... 3 1.3 Integrins, the key mediator of cell-ECM adhesion ................................................. 4 1.3.1 Overview .............................................................................................................. 4 1.3.2 Structural control of function ............................................................................... 5 1.3.3 Extracellular domain of Integrin .......................................................................... 6 1.3.4 Transmembrane domain of Integrin ..................................................................... 8 1.3.5 Cytoplasmic tail of Integrin ................................................................................. 8 1.3.6 Integrin signalling: Integrin activation ................................................................. 9 1.3.7 Inside out Integrin activation ............................................................................... 9 1.3.8 Outside in Integrin activation ............................................................................. 10 1.3.9 Integrins and mechanical force transmission ..................................................... 11 1.4 Talin, the main regulator of cell-ECM adhesion .................................................. 12 1.4.1 Overview ............................................................................................................ 12 1.4.2 Talin binding partners and domains ................................................................... 13 1.4.3 Talin activation and recruitment ........................................................................ 14 1.4.4 Talin as a mechanosensor .................................................................................. 14 1.5 The ECM .................................................................................................................. 15 1.5.1 ECM composition .............................................................................................. 15 1.5.2 The ECM also drives morphogenesis ................................................................ 16 vi 1.6 The turnover of the Integrin-mediated adhesion .................................................. 16 1.6.1 Overview ............................................................................................................ 16 1.6.2 Integrin trafficking in cell culture ...................................................................... 17 1.6.3 In vivo turnover analysis of the Integrin-based adhesion components .............. 19 1.7 Aims, hypothesis and rationale ............................................................................... 19 1.8 Chapter 1 figures ..................................................................................................... 22 CHAPTER TWO: Materials and methods ...................................................................... 24 2.1 Fly genetics ............................................................................................................... 24 2.2 FRAP experiments ................................................................................................... 25 2.3 Integrin activation assay ......................................................................................... 26 2.4 Endocytosis inhibition assay ................................................................................... 26 2.5 Mathematical modelling .......................................................................................... 26 CHAPTER THREE: Results ............................................................................................. 28 3.1 In vivo quantitative analysis of Talin turnover in response to force ................... 28 3.1.1 Development of a mathematical model and a modified FRAP approach to study Talin turnover .............................................................................................................. 28 3.1.2 Analyzing the turnover of Talin under increased force ..................................... 31 3.1.3 Resolving the mechanism by which the turnover of Talin is regulated by increased force ............................................................................................................ 33 3.1.4 Analyzing the turnover of Talin under decreased force ..................................... 35 3.1.5 Uncovering the mechanism by which the turnover of Talin is regulated by decreased force ............................................................................................................ 36 3.1.6 Reducing FAK activity partially mimics the effect of increased force on Talin turnover ....................................................................................................................... 37 3.1.7 Changes in rate constants underlie developmental regulation of Talin turnover ..................................................................................................................................... 38 3.1.8. Chapter 3.1 table ............................................................................................... 40 3.1.9 Chapter 3.1 figures ............................................................................................. 41 3.2 In vivo regulation of Integrin turnover by outside-in activation ......................... 55 3.2.1 Outside-in activation regulates Integrin turnover by divalent cations stabilizes cell-ECM adhesion by decreasing Integrin turnover. ................................................. 55 3.2.2 Activating Integrin mutants regulate turnover similarly to treatment with divalent cations............................................................................................................ 56 3.2.3 Integrin mutations that affect outside-in activation fail to regulate Integrin turnover upon treatment with divalent cations. ........................................................... 57 3.2.4 ECM reduction destabilizes cell-ECM adhesion by increasing Integrin turnover. ..................................................................................................................................... 58 vii 3.2.5 Integrin turnover is developmentally regulated by Integrin activation. ............. 58 3.2.6 Rap1 regulates Integrin turnover downstream of outside-in activation. ............ 60 3.2.7 Chapter 3.1 table ................................................................................................ 61 3.2.8 Chapter 3.2 figures ............................................................................................. 62 3.3 In vivo analysis of ECM components turnover ..................................................... 73 3.3.1 The major ECM proteins, Collagen and Laminin, undergo turnover ................ 73 3.3.2 Laminin ECM is remodelled upon Integrin activation ...................................... 73 3.3.3 Chapter 3.3 figures ............................................................................................. 74 CHAPTER FOUR: Discussion .......................................................................................... 75 4.1 In vivo quantitative analysis of Talin turnover in response to force ................... 75 4.2 In vivo regulation of Integrin turnover by outside-in activation ......................... 78 4.3 In vivo analysis of ECM components turnover ..................................................... 80 4.4 Model of cell-ECM adhesion turnover regulation throughout development ..... 80 4.5 Caveats ...................................................................................................................... 81 4.6 Future directions ...................................................................................................... 82 4.7 Summary ................................................................................................................... 83 REFERENCES ................................................................................................................... 84 APPENDIX: Supplemental materials and methods ........................................................ 92 Mathematical model for Talin and other IAC proteins ............................................. 92 Mathematical modeling ............................................................................................... 92 Parameter estimation and bootstrap confidence intervals ........................................... 94 Mathematical model for Integrin