The gene Lr34 has contributed to durable resistance to leaf rust caused by Puccinia triticina in wheat worldwide. The closely associated leaf tip necrosis is generally used as the gene's marker. Lr34 has been postulated in many Indian bread wheat cultivars including 'C 306', based on the associated leaf tip necrosis and a few other field and glasshouse observations. The present study showed monogenic control of adult-plant resistance in 'C 306' to leaf rust pathotype 77-5 (121R63-1). The F 2 segregation in the crosses between 'C 306' and the two known carriers of Lr34, 'Line 897' and 'Jupateco 73' 'R' fitted a digenic ratio. The F 3 families derived from the susceptible F 2 segregants were true breeding for susceptibility, proving the absence of Lr34 in 'C 306'. The cross between 'Line 897' and 'Jupateco 73' 'R' did not segregate for susceptibility. Resistance in the cross 'Agra Local' (susceptible) x 'C 306' was associated with leaf tip necrosis, showing that the leaf rust resistance gene in 'C 306' was associated with leaf tip necrosis, but was different from Lr34. This gene is being temporarily designated as Lr'C 306'. Hence, leaf tip necrosis cannot be considered as an exclusive marker for selecting Lr34 in wheat improvement.


The report is the result of an investigative study on the scarcity of milkfish fry in the Philippines, a collaborative effort of BFAR, SEAFDEC, PCAMRD and ICLARM. The study aimed to monitor fry production in selected sites in the Philippines for a period of one year; assess the current demand for milkfish fry; and provide on-the-job training on data collection and recommend a system for continuous collection of data on fry production.


The article describes why, when a high-rise structure needed a high-quality, long-term repair solution for a severely distressed parking deck slab, the answer was a full deck replacement. The factors leading to the decision are discussed. When deterioration is very severe, overlays are not practical. This is especially true when corrosion of the top reinforcement is so advanced that it loses its bond or cross-sectional area and flexural moments have redistributed, resulting in the significant overstress of the bottom reinforcing bars. When total demolition is not posible, full deck replacement is the only viable solution.


As caches become larger and shared by an increasing number of cores, cache management is becoming more important. This paper explores collaborative caching, which uses software hints to influence hardware caching. Recent studies have shown that such collaboration between software and hardware can theoretically achieve optimal cache replacement on LRU-like cache.
 This paper presents Pacman, a practical solution for collaborative caching in loop-based code. Pacman uses profiling to analyze patterns in an optimal caching policy in order to determine which data to cache and at what time. It then splits each loop into different parts at compile time. At run time, the loop boundary is adjusted to selectively store data that would be stored in an optimal policy. In this way, Pacman emulates the optimal policy wherever it can. Pacman requires a single bit at the load and store instructions. Some of the current hardware has partial support. This paper presents results using both simulated and real systems, and compares simulated results to related caching policies.


With the development of computer and electronic technology, field weed recognition and weed control technology move toward intelligentization and automatic weed control system has become a hot research subject. Automatic weed control system consists of four main modules,including guidance system module, image acquisition and processing module, weed recognition module and weed control module. The four modules were reviewed, the current problems were analyzed and future research were pointed out.


Soil water regimes and water extraction patterns estimated over a period of two years are described for two plantation communities of semi-arid shrubs, Atriplex vesicaria Hew. ex Benth. and A. nummularia Lindl., growing on the same soil type under identical climatological conditions near Deniliquin, New South Wales.

In spite of poor water flow properties of the soil, surface run-off was negligible.About 90% of the extractable water was stored in the top (45 cm) soil layer. Both species withstood exceedingly low water potentials, although A, vesicaria reduced soil water to a much lower water potential than did A. nummularia. Water potentials at depths below 60 cm were always – 15 bars and remained constant. Water extracted beyond –15 bars amounted to 41% more than the water available within conventionally accepted water potential limits (between –0.3 to – 15 bars). During Slimmer, the plant water potential of A. vesicaria fell to much lower values than that of A. nummularia. Relationships between relative leaf water content and plant water potential differed between the two species, and the suggestion is made that at low plant water potential, leaf targidity of A. vesicaria would be higher, and thus this species would have a higher tolerance to desiccation.

On a yearly, half-yearly and even a quarterly basis, evapotranspiration (FT) of the two communities did not differ. Fortnightly FT rates were similar during winter but during early summer, the initial ET rate of A. vesicaria was higher than that of A. nummularia; A, nummularia can therefore conserve water for later use. These differences in water extraction patterns and evapotranspiration were associated with differential rooting characteristics and probably differential stomatal functioning. The relationships between fortnightly ET/FO (ratio of actual evapotranspiration to that from a Class A pan) and profile water content, for both communities, were linear but different.


This paper is an attempt to assess the changes taking place in the vegetation communities found on the fringes of tropical rainforest in Nigeria over a 28-year period. The study made use of aerial photographs (1963 and 1973) and Landsat TM (1991). Landsat TM was digitally analysed, while aerial photos were subjected to an analogue procedure. The results show that the forest community receded at an annual rate of 1.90% between 1963 and 1991, while regressive succession was already in progress in the area. The intensity of agricultural activity was noted to have made the area vulnerable to savanna incursion. This paper highlights the prospects and problems of using remote sensing techniques in surveying Africa's rural landscape with its bewildering complexities. Some policy recommendations are suggested in the paper.


Recently, robots have become a topic of interest with regard to their functionality as they need to complete a large number of diverse tasks in a variety of environments. When using traditional mechanical components, many parts are needed to realize complex deformations, such as motors, hinges, and cranks. To produce complex deformations, this work introduces a smart soft composite torsional actuator using a single shape memory alloy (SMA) wire without any additional elements. The proposed twisting actuator is composed of a torsionally prestrained SMA wire embedded at the center of a polydimethylsiloxane matrix that twists by applying an electric current upon joule heating of the SMA wire. This report shows the actuator design, fabrication method, and results for the twisting angle and actuation moment. Results show that a higher electric current helps reach the maximum twisting angle faster, but that if the current is too low or too high, it will not be able to reach its maximum deformation. Also, both the twisting angle and the twisting moment increase with a large applied twisting prestrain, but this increase has an asymptotic behavior. However, results for both the width and the thickness of the actuator show that a larger width and thickness reduce the maximum actuation angle of the actuator. This paper also presents a new mechanism for an SMA-actuated active catheter using only two SMA wires with a total length of 170 mm to bend the tip of the catheter in multiple directions. The fabricated active catheter's maximum twisting angle is 270°, and the maximum bending curvature is 0.02 mm−1.


Our research focuses on two goals. First, we seek to demonstrate that data quality is an important component of machine learning tools and that the quality of our data should be carefully considered when developing and using these tools. We believe that while the importance of data quality is now understood in the business community, where researchers have equated quality decision making to earnings, in the machine learning community this realization has not yet occurred. Therefore, we embark upon research into the effects of data quality upon these algorithms in an effort to demonstrate that data quality is a large factor in the outcomes of these algorithms and should be given more respect in their design. Second, after providing evidence that data quality is a large factor in these algorithms, we develop and test some preliminary methods which incorporate data quality assessments, thus creating more robust and useful algorithms. We believe these modifications and methods can have profound effects upon the usage of these machine learning algorithms in actual practice, particularly in the Law Enforcement community.


majority of its own political faith in the legislative body, has hardly been approximated. There is rather a negative conception, due largely to the differences within the parties in the chambers, which makes possible the building of governments supported by an absolute majority and which may have long tenure of office. Minister Erich of Finland recalled that in his country parliamentary government was not introduced until 1917, and that therefore there may be just reasons for the lack of faith which many as yet evidence toward it. The building of a government in Finland is frequently a difficult matter because of personal considerations, and the average life of a ministry has been only about ten months. The position of the president under the constitution, as well as the personal strength of the chiefs of state, has to some extent ameliorated these difficulties. One consequence of minority governments, however, has been that the party represented in the ministry frequently forgets all about its program in order to remain in office and not to risk its position. This, together with other features, has led to no little dissatisfaction with the existing regime. At the last session of the congress, the question of permanent organization was discussed. It was felt by everyone that the continued cooperation of northern scholars and statesmen in these fields was both desirable and necessary, and that conferences similar to the present one might profitably be held every three or four years. A committee was created within each country to work in conjunction with the others in making further arrangements with this end in view. That the 1930 congress aroused considerable interest throughout Scandinavia was evidenced by the active collaboration of members of the four governments and the large amount of space given the proceedings, not only by the Stockholm press, but by the leading papers of outlying smaller cities. E R J C C Y R I L B E L L Q U I S T . 2


It is a common environmental and hydro-geological problem that groundwater system is contaminated by petroleum hydrocarbons. An important step of pollution control and treatment is aquifer vulnerability assessment. In this paper, a karst fissure groundwater system where a refinery located above is taken as research object. Firstly, we analysis and determine principal factors impacting aquifer vulnerability to petroleum contaminants. These factors are used as evaluating indexes in the assessment. Secondly, with the consideration of uncertain and spatial attributes in assessment, a fuzzy vulnerability assessment method is proposed based on fuzzy variable set theory and geographic information system (GIS). Using the models and method, we finally obtained the assessment results map of aquifer vulnerability and it shows that the models and methodology are reasonable and feasible.


The present study was performed to observe the change of QT interval by sympathetic stimulations in patients with the long QT syndrome (LQTS). The study group consisted of 6 children with LQTS and 6 healthy children without QT prolongation. All LQTS patients had syncopal episodes. The QTc and ΔQTc% ([QTC interval after examination ‐ QTc interval at rest]/QTc interval at rest × 100) by treadmill testing, face immersion, and isoproterenol were examined. One minute after peak exercise of treadmill testing, the changes in the QTr, interval were not significant in either group, but ΔQTC% was larger in the LQTS group than in the control group (+ 11.0 ± 12.1% vs ‐2.6 ± 3.2%;P= 0.02). The QTc interval at the shortest RR interval during face immersion was prolonged in the LQTS group (0.47 ± 0.01 s to 0.51 ± 0.04 s; P = 0.02), but there were no significant changes in the control group (0.40 ± 0.03 s to 0.41 ± 0.03 s; P = NS). ΔQTC% was larger in the LQTS group than in the control group (+ 10.0 ± 7.3% vs +1.1 ± 5.5%; P = 0.04). In the LQTS group, the RR interval was shortened (P = 0.009) and QTc interval was prolonged (P = 0.0008) after isoproterenol infusion. These sympathetic stimulations amplified the TU abnormality in the LQTS group. By observing the TU changes caused by face immersion, we hoped to find a possible new method with which to diagnose LQTS. The combination of these examinations may be helpful in screening the borderline cases of TU abnormalities.


wireless sensor network is the growing field of research having capacity to help the mankind with its usage in varied areas like military surveillance, medical etc. However these networks are vulnerable to certain attacks like black hole, wormhole and selective forwarding. In this paper selective forwarding attack is analyzed on varying number of attacker nodes and its impact on different performance parameters. It is concluded that the performance of the entire network is degraded with the increase in the number of malicious nodes.


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The China-Pakistan Economic Corridor (CPEC) is one of the huge and promising projects in the history of the world in general and of Pakistan in particular. The significance of this work on CPEC can be gauged that it has discussed few aspects i.e. engagement of Baloch people, special economic zones etc., which are rarely touched by the academia and professionals. This work reviews on different aspects of the project opined by well-known researchers and experts of the field. Through an analytic and logical reasoning this work has elaborated about the opportunities and challenges nagging to this huge project. This paper has found that there are innumerable challenges which government faces to execute and operationalize of this project. But the government is strongly determined to remove these challenges and it has taken some pragmatic initiatives for the eradication of challenges in the way of this very project and ease to develop different projects under the umbrella of CPEC.


Biochemical (electrophoresis and mitochondrial DNA) and morphological analysis are important tools for the characterization of strains. Reference is made to studies conducted in the framework of the Genetic Improvement of Farmed Tilapias project to establish a new base tilapia population for culture purposes, describing the basic concepts of electrophoresis and morphometric analysis.


The measurement of depth of a laser capillary in industrial conditions by Optical Coherence Tomography technique is demonstrated in this work. This paper highlights the results achieved by the recent combination of ultrasound sensitive membrane-free optical microphone by XARION and PRECITEC's OCT IDM system. Joint interpretation of the ultrasound spectrograms and the digging curves of the keyholes enables better understanding of the dynamics of the melted metal and determination of the ideal welding parameters.


Three‐terminal vertical quantum structures using a self‐aligned sidewall gating technique have been developed. Resonant tunneling transistors with physical widths of about 0.7 μm demonstrate pinch‐off of the resonant peak at room temperature. Comparable gating characteristics for forward and reverse drain‐source biases indicate that the gating action is vertically uniform, making this topology suitable for the fabrication of low‐dimensional structures and study of multiple quantum well devices.


Aims To determine the utility of ultrasonography for the preoperative localization of enlarged parathyroid glands in primary hyperparathyroidism, and to compare this method with 99m technetium sestamibi scintigraphy. Patients and Methods The results of ultrasonography for localization of enlarged parathyroid glands were determined in 80 consecutive patients with primary hyperparathyroidism and compared with findings at surgery and with the results of 99m technetium sestamibi scintigraphy. Results Ultrasonography predicted surgical findings in 61 of 80 patients (76.1%), including 59 of 76 patients with solitary parathyroid adenomas (77.6%) with a sensitivity of 83.5 % and a positive predictive value (PPV) of 89.7%. Sestamibi scintigraphy findings were correlated with surgical findings in 63 (78.8%) patients including 62 of 76 patients with solitary eutopic parathyroid adenomas (81.5%), with a sensitivity of 85 % and a PPV of 91.3%. Conclusion Sensitivity and positive predictive values of ultrasonography are not significantly different from values of sestamibi scintigraphy in localization of pathologic parathyroid glands in primary hyperparathyroidism.


The white population of the United States had practically reached a stationary rate of growth in 1930, if only fertility is considered. Its potential rate of growth declined in the ensuing years until at present its rate fluctuates around 90, indicating a potencial rate of decline of about 10 per cent in a generation. Whereas in 1930 the white population as a whole maintained a reproduction rate sufficient to keep it stationary, some entire states in the Union and some classes within almost all the states showed rates below their ability to maintain their numbers. An analysis of the rates by states, by states and classes-i.e., rural-farm, rural-nonfarm, and urban populations-and by states and size of community, is presented in this study. It seems that the future growth and distribution of the population will depend on the rate at which the potentially rapidly declining city population will be replaced by the rapidly growing rural populations of the southern states. Should the newcomers adopt the city mode of life, the potential rate of decline of the population as a whole will be accelerated. In general, the analysis seems to point toward a narrowing in the range of the differentials between the rural and the urban classes, and between North and South. A narrower range will, of course, cause a greater decline. Such quantitative changes will bring about qualitative changes, i.e., older and more conservative populations. Moreover, the South, acting as the source of the population replacement, is likely to exercise in the future a greater influence on our political and social life.


In this study,the author use TOPCARES-CDIO education idea as the instruction,starting from business Japanese basic series of courses,to explore connotation construction,teaching mode,evaluation,case database and test database construction.


State-of-the-art catalysts SAPO-34 and ZSM-5 were tested for the reaction of Methanol-toHydrocarbons. In order to capture the rapidly changing product spectrum during deactivation, suitable test methods were developed such as a low severity protocol which prolongs the deactivation timescale and a commercially relevant high severity protocol.


Purpose An uncommon congenital anomaly of the eyebrows is described. Methods Case report and review of the literature. Results Two articles in the English literature were found describing patients similar to ours. Conclusions Congenital upward tenting of the midportion of the eyebrows, resembling the eyebrow line of an owl, is uncommon. This anomaly is thought to be transmitted in an autosomal dominant fashion and may be accompanied by myopia and strabismus, but has not been associated with systemic disease.


This research aim to stay the effect green manure dose of Tithonia diversifolia on growth and result of maize crop ( Zea mays L.) in farmer farm in Sidera of Sub district Sigi Biromaru of Regency Sigi, Mei-Juli 2013. Field experiment the Random Device Blok Disaign (RAK) consisted of 4 treatment, that is  B1 = Without green manure, B2 = Green Manure of Tithonia diversifolia 5 ton of per ha, B3 = Green Manure of Tithonia Diversifolia 10 ton of per ha, B4 = Green Manure of Tithonia diversifolia 15 ton of per ha. Every treatment repeated three of times, consisted of 12 unit. Result indicate that the green manure Tithonia diversifolia can improve the growth and result of maize crop ( Zea mays L.) With the green manure of Tithonia Dose 10 (ton)  per ha can improve result of maize crop equal to 9.2 ton / ha.


Dynamic measurement capabilities are required for smart meters in the development of smart grid.So it is important to test the dynamic measurement capabilities of smart meter.For this purpose,an evaluation method based on a DDS signal generator is presented and specific targets are given in this paper.With models built,an adjustable DDS experimental signal is realized on the FPGA platform.Simulation results show that this method is reliable for the dynamic measurement capabilities evaluation of smart meter.


Objective:To investigate the mechanism of protective effects of fluvastatin on myocardial ischemia-reperfusion injury in hyperlipidemia rabbits. Method:The rabbits were subjected to gastric intralipid perfusion for consecutive 3 weeks to develop models of hyperlipidemia. 40 hyperlipidemia rabbits were randomly divided into 4 groups (10 in each group): IR (ischemia-reperfusion) group, S (sham-operation) group, F10 and F75 group (rabbits received fluvastatin 10 mg/kg or 75 mg/kg by gastric gavage 3 hours before IR). Electrocardiogram and cardiac function were recorded during the experiment. At the end of reperfusion, ischemic myocardium at risk was assessed with Evans blue dye and infarct size by triphenyltetrazolium chloride. Myocardial nitric oxide synthase (NOS) isoenzyme activity was measured with colorimetric method. Result: After ischemia-reperfusion, iNOS activity and myocardial infarct size decreased and cardiac function improved significantly in F10 and F75 groups compared with IR group. iNOS activity was lower and myocardial infarct size was smaller significantly in F75 group than in F10 group. The difference of cardiac function did not reach statistical significance between F10 and F75 groups. Conclusion:The increase of iNOS activity may be one of the important factors in inducing myocardial ischemia-reperfusion injury. The myocardial protection mechanism of fluvastatin may be attributed to its effect on decreasing iNOS activity. Fluvastatin 75 mg/kg may be better than 10 mg/kg in myocardial protection.


ABSTRACT In this study we tested the current taxonomic model of the trematode superfamily Hemiuroidea, according to which the genus Paraccacladium belongs to the family Accacoeliidae. We reconstructed the phylogeny of the hemiuroid Clade A using novel 28S rRNA gene sequences of Paraccacladium sp., Derogenes varicus, Progonus muelleri and Lampritrema miescheri as well as data available in GenBank. Based on phylogenetic data, the genus Paraccacladium should be assigned to a separate family, the Paraccacladiidae Bray & Gibson, 1977 stat. nov. The morphological differences between the Paraccacladiidae and the Accacoeliidae are the absence of a uroproct, anteriorly directed diverticula of intestinal caeca, and the position of Mehlis' gland, posterior or postero-lateral to the ovary. Phylogenetic analysis indicates a sister relationship between the Derogenidae and the Sclerodistomidae. It also shows that the Paraccacladiidae, on the one hand, and a group of families, the Accacoeliidae, Hirudinellidae and Syncoeliidae, on the other, share the most recent common ancestor. Our data support the hypothesis that the genus Lampritrema is affiliated to the Hirudinellidae. Genetic divergence between North Atlantic and North Pacific isolates of D. varicus was also determined.


The utility model relates to a cooling device used for an auxiliary mine axial flow fan, which comprises a casing (1), an air inlet duct (2) and an air outlet duct (3); the casing (1) is provided with a cavity body and arranged in a ventilation air flow channel, a motor body of the auxiliary mine axial flow fan is arranged in the cavity body of the casing (1), the air inlet duct (2) and the air outlet duct (3) which are respectively communicated with the cavity body of the casing (1) are respectively arranged on the casing (1), the inlet end of the air inlet duct (2) and the outlet end of the air outlet duct (3) receptively extend on the outer side of a main air flow channel, the inlet end of the air inlet duct (2) is communicated with a fresh air flow channel, and the outlet end of the air outlet duct (3) is communicated with the ventilation air flow channel; therefore, the service life of the auxiliary mine axial flow fan is prolonged, and the airflow resistance to the main air channel is reduced.


While shifting mortality was conceptualized as a shift in mortality rates across age, trends in variability of age at death are used to evaluate whether or not a country is exhibiting signs of shifting mortality. In this paper, we reexamine the relationship between mortality change and trends in variability age of death in order to evaluate whether shifting mortality is an inevitable outcome of the mortality transition. Through simulation exercises, perturbation analysis, and decomposition analysis, we arrive at a better understanding of how initial mortality conditions and the age-pattern of mortality change interact to produce mortality compression, expansion, or shifting. We find that proportional mortality change that is fixed across ages does not necessarily lead to a parallel shift in the death distribution. In addition, we demonstrate that certain initial mortality conditions are particularly primed for compression. *Department of Demography, University of California, Berkeley Please send comments to email@example.com Preliminary draft: please do not cite or circulate without permission


(From the Chemical Laboratory, Santa Barbara Cottage Hospital Research Institute, Santa Barbara, Calif.) (Received for publication September I5, I94 I) The present report is concerned with a comparison in Marsh-Buffalo mice of the action of estradiol with that of theelin when injected over a long period and in massive doses. Studies performed in this laboratory indicate that the Marsh-Buffalo strain is highly suscep- tible to mammary cancer and markedly resistant to the carcinogenic effect of exogenous theelin. Since the relation between estradiol and theelin in catabolism is not known, it appeared desirable to ascertain whether estradiol would be more effective, and whether the intact ovary inhibited the influence or acted synergisti- cally to exogenous estradiol. Suntzeff et al. (5) state, "In strain New Buffalo nonbreeding ,nice injected with estrin the percentage of tumors developing was relatively low, although it was somewhat higher than in nonbreeding control mice. There is thus some indication that the mammary gland of New Buffalo mice is relatively resistant to the stimulating action of estrin." Since these workers used only 2 to 7 mice per experiment, this work must be regarded as pre- liminary in nature. We were, therefore, prompted to repeat these experiments on a larger scale, since resistance to carcinogenesis caused by theelin in a high cancer strain would be a phenomenon which could not readily be ignored. The results of our experi- ment published to date (I), in which crystalline theclin was used, confirmed the original suggestion of Suntzeff et al. that the mammary gland of the Marsh-Buffalo mouse is relatively resistant to the stimulating action of estrin. The incidence of mammary cancer in our control Marsh-Buffalo mice parallels the data originally published by Marsh (3) and confirmed by Murray and Hoffman (4)- It should be noted that the data of Suntzcff et al. indicate a considerably lower cancer incidence, and in this respect only is there a divergence in results. Since the studies reported in this paper were completed, Suntzeff et al. (6) have published additional data on the Marsh-Buffalo strain, and conclude that the estrogen dosage raised the incidence of tumors in nonbreeding mice to approximately that of the breeders. This deduction is obviously unwarranted as the standard deviation of the mean for the number of animals used equals the difference. In our opinion, the data again demonstrate that mice of the Marsh-Buffalo strain are highly resistant to estrogen carcinogenesis, and justify the characterization of this strain as having a relatively low incidence of cancer in Dr. Loeb's laboratory. EXPERI~ENTAL At 22 days of age, litter-mate females were divided into 3 groups of 4 ~ mice per group. One group served This investigation was aided by a grant from The Inter- national Cancer Research Foundation. as a control and received injections of sesame oil. An- other group received injections of estradiol. 1 The third group was ovariectomized at weaning, and received estradiol in the same amount as did the group os intact mice. The amount of estradiol administered in these experiments corresponds to the larger amounts os theelin administered in our previous experiments with theelin (I). The estradiol was dissolved in sesame oil (2 mgm. per cc.) and was administered intramuscu- larly or subcutaneously in doses of o.o 4 cc. twice weekly for a period of 6 months. Each surviving mouse re- ceived a total dose of 3.3 to 4.2 mgm. estradiol. The controls received o.o 4 cc. sesame oil twice weekly over a 6-nlonth period. The first injections were given at the age of r to 2 months. Since the purpose of these experiments was to com- pare the action of estradiol with that of theelin, the data of experiments with mice receiving theelin, which have been published (i), are retabulated and compared with experiments in which estradiol was used. Forty mice received theelin in each experimental group. In Tables I and II are tabulated the cumulated percentage incidences of adenocarcinoma of the breast, lympho- sarcoma, spontaneous death, and combined influences removing animals from the experiment. Spontaneous death is used as a measure of toxicity. At autopsy, some of these animals were found to have lympho- sarcoma. With the development of a palpable tumor, the animal was removed from the experimental group and sacrificed after the tumor had developed in di- ameter to 1.5 cm. RESULTS Toxicity.--In the controls of both the theelin and estradiol series, the 13 and i2 per cent incidence (cumulative) of death before the 7th month is higher than is usually encountered for control mice. In a series of I2o virgin female mice housed and fed under strictly analogous conditions, but not given sesame oil, only I mouse died in a similar period. A slightly toxic effect of the sesame oil is indicated. In same 7- month period, 35 per cent of the theelin-dosed mice, x The authors are indebted to the Schering Corporation for the supply of alpha estradiol. 52


Hylleraas method variational calculations with up to 458 expansion terms are reported for the n $^{1}D$, n $^{3}D$ terms and for the n $^{1}F$, n $^{3}F$ terms (n=4\char21{}8) of neutral helium. Convergence arguments are presented to obtain new estimates of the exact nonrelativistic energies of these terms. The reliability of the estimates ranges from 3\ifmmode\times\else\texttimes\fi{}${10}^{\mathrm{\ensuremath{-}}10}$ a.u. in the worst case to ${10}^{\mathrm{\ensuremath{-}}11}$ a.u. in the best case. The nonrelativistic singlet and triplet energies are combined with previously calculated values for relativistic and other small energy contributions to evaluate the total ionization energies for the n D and n F levels. Comparisons of the n $^{1}D$ and n $^{3}D$ energies with other calculations and available data yield improved values for relativistic contributions. The calculated relativistic n F ionization energies agree with values based on core-polarization theoretical n G and n H energies within deviations of 3 MHz (5\ifmmode\times\else\texttimes\fi{}${10}^{\mathrm{\ensuremath{-}}11}$ a.u.) for n=5 to 1 MHz (1.5\ifmmode\times\else\texttimes\fi{}${10}^{\mathrm{\ensuremath{-}}11}$ a.u.) for n=7,8. The calculated n F fine-structure separations generally agree with experiment for n=5\char21{}8 within uncertainties of the order of 1 to 0.1 MHz. Predicted values given for the 4 F fine-structure separations and the ${4}^{1}$F ionization energy are probably accurate within a few MHz.


Method for transporting physical objects, wherein at least one physical object is transported from a sending station to a receiving station, wherein the transport occurs through at least one physical router, wherein the physical router executes a decision about parameters of transport to another physical router or to the receiving station, characterized in that information for handling and moving the physical object is generated and transferred to a logical node, wherein the information is used to make a decision about a handling and moving the physical object according to manipulation and move packets in a telecommunications protocol, and wherein the logical node transfers the decision to the sending station and / or at least one allocator physical router executing the decision.


In this paper, a supplementary damping control scheme for static synchronous compensator (STATCOM) is proposed to stabilize the oscillation caused by subsynchronous control interactions (SSCI) phenomenon in a series-compensated doubly fed induction generator (DFIG) based wind farm. Various system conditions determine the oscillation frequency, which is usually different for different SSCI events. Therefore, it is a great challenge to design an efficient and reliable damping controller to stabilize the SSCI. A damping controller based on combination of filters, gain, and phase-shifts is designed for STATCOM controller. With the proposed scheme, the STATCOM is able to provide positive damping for a wide range of system conditions, and thus covering a wide band of oscillation frequencies. The performance of the proposed scheme is validated on an aggregated model of an actual wind power system using Simulink environment. The time-domain simulations have demonstrated the effectiveness of the proposed scheme for mitigating the SSCI at various oscillation frequencies.


In recent years, Model Predictive Control has been regarded as one of the most reliable advanced control methods widely used in industrial and nuclear processes. Model predictive control uses a system model to forecast its future response, and also treats a real-time optimization algorithm to choose the best control action that leads the predicted output to the reference. The overall design goal of a predictive control model is to compute the trajectory of a future manipulated variable input signal to optimize the future behavior of the plant output. Optimization is performed within a limited time window by providing information at the beginning of the time window. This paper proposes a predictive controller MPC model for multiple input-output systems. The design of the controller includes the development of a model of the state space system for the tank system, then the design and the simulation of the MPC controller for the developed model system. The variables to be controlled are the temperature and the liquid level of the tank by changing the MPC's parameters.


This chapter explores both the end of war (and its accompanying diction), and the end of Andrew Clark's 'Words in War-Time' project in 1919, and the afterlives that this reveals. The language of memory, and public and private memorialization, is an important part of this. Poppies, war shrines, and memorial services are all part of Clark's process of attentive record. So, too, was the shifting language of the souvenir. As war ended, Clark, of necessity, also gathered his own last words. Nevertheless, as he stressed, trying to create a history of war-time usage in a single-handed project now seemed increasingly foolhardy. He was acutely aware of the imperfections of what he had achieved. 'Words in War-Time' remained incomplete and unrevised (Clark died in 1922) – an archive of scraps and annotations, both fascinating and frustrating. This chapter concludes by examining his legacies, insights, and the enduring value of his work.


Background:  To determine the influence of patient and tumor characteristics on clinical outcomes in patients with early‐stage non‐small cell lung cancer (NSCLC) treated with helical intensity modulated stereotactic body radiotherapy (SBRT).


The results of experimental studies of the kinetics of wet scrubber with a vortex plate. Rational technical parameters of the density of irrigation and the purified gas. The efficiency of the vortex plates for dust removal.


Based on the improved trial test of a construction section of expansive soil subgrade filling in Small Crow first class road in Yi Chang, a comparative analysis about the improvement on the swell-shrink performance of expansive soil test sample by adding lime, cement, fly ash, weathered sand is made. From the applicability and economic perspective, weathered sand improvement with the best effect. The best construction mixing sand ratio for medium and strong expansive soil is determined as10%, the expansive soil after improved treatment can be used as the first class road subgrade filling.


The invention relates to a game target or dart board, comprising a support, a plurality of individual, relatively movable target elements belonging to an overall spider, each having an indirectly comprises the support opposite inner surface and an outer surface with openings. To realize a reliable backlight dart board and to facilitate their assembly, is provided: that each target element, starting from the inner surface, at least one Kontaktfuselement, oriented toward to the support, in that the at least one Kontaktfuselement can pass through an associated opening of a Hinterleuchtungs-circuit board, which indirectly following the spider out is the carrier when an opening of the target element is hit by an arrow, that is, mounted on the Hinterleuchtungs circuit board outside the openings for Kontaktfuselemente, but in the area of the target element at least one light emitting diode, such as LED, that directed the layer structure in the direction of acting at least one Kontaktfuselementes Hinterleuchtungs the circuit board toward follows a rubbery damper plate and a printed circuit board with the applied switching contact elements and the contact elements of the printed circuit board by bulging of the damper plate, caused by acting Kontaktfuselemente, out be redeemed.


Crystals of 6-ketononanolide (oxacyclodeca-2,6-dione) are orthorhombic, a = 8.886, b = 16.407, c = 11.965 A, space group Pbca, with 8 molecules in the unit cell. The structure has been solved with the help of direct methods and refined by full-matrix least-squares analysis of three-dimensional intensity data. The conformation of the ring is similar to that previously observed in several cyclodecane derivatives, with the ring oxygen and carbonyl groups so situated as to minimize the number of transannular H … H contacts. Evidence for transannular O(ether) … C(carbonyl) donor-acceptor attraction is discussed.


The disclosed multilayer tree route method for distributive certification of wireless self-organizing network comprises the group generation, route group maintenance and group selection. The key of this invention is to reconstruct the network structure into a multilayer group tree topology. This invention improves certification efficiency, reduces network spending, and improves the network security and reliability.


The cost-benefit analysis of waste recycling and separating business in Senangkhanikom District, Amnatcharoen Province, Northeastern Thailand was studied. Results showed the Net Present Value (NPV) was 313,502 baht. The Internal Rate Return (IRR) and Payback Period (PB) were 8% and 4.5 years, respectively. Problems and obstacles reports were in the medium level ( = 3.35). It was found that the most problems and obstacles of the business was marketing ( = 4.23). The rest of the problems and obstacles were the lack of technology ( = 3.84) and financial liquidity as well as cash holdings for buying products ( =2.76), respectively. It is recommended that the business could grow its profits and satisfactory investment as well as could help to improve the communities in many aspects such as making money by selling waste materials, reducing pollutants into the environment, and building a better living environment.


Diludine was used to feed the Monopterus albus for 40 days. The results showed that the gonadosomatic indexes,utterly pregnant eggs and hatching rate from female eels fed with supplementing diludine were 4.55%,2 258 egg cell·wei~(-1) and 96.85% respectively and significantly higher than those of the control group(1.87%,1994egg cell·wei~(-1) and 80.28% respectively). The amounts of eggs were increased to 13.24%,hatching rate was enhanced 20.64%;SOD activity and MDA content of ovary,liver and muscle were decreased evidently.These results indicate that 0.15 mg/kg diludine added to the fish diet improved the propagation,quality of eggs and hatching rate significantly.At the same time,diludine could resist oxidize and prevent fat from oxidizing.


The present invention discloses a fuel additive, wherein the dialkyl carbonate comprises from 0.1 to 99.8%, bis-cyclopentadienyl iron 0 to 80%, benzene Benzotriazole 0 to 80%, ethylene oxide condensates of fatty alcohols with 0.1 to 80% ethylene oxide condensates of alkylphenols with from 0.05 to 50% other components. Which can be widely used in various grade of gasoline variety of various types of motor vehicles, marine diesel engines, locomotives, industrial boiler fuel, diesel fuel, ethanol fuel, bio-diesel, and heavy oil. The advantage is clean, non-toxic, add less, can instantly improve the quality of fuel, and promote combustion efficiency, significant savings in fuel consumption and reduce harmful exhaust and enhanced engine power and engine protection to extend engine life.


Virtualization is a technique used to abstract the operating system from the hardware. The primary gains of virtualization is increased server consolidation, leading to greater hardware utilization ...


The heat-resistant release base paper was successfully prepared by adding the heat resistant additives in the pulp and the process of multi-layer coating on the paper surface,and the effects of the amount of sizing agent and heat-resistant additives on the heat-resistant properties were investigated.The surface structure was characterized and the heat-resistant mechanism of the heat-resistant release base paper was analysed.The results demonstrated that a heat-resistant thin film on fiber surface was formed,when the paper was heated under the temperature between 180℃ and 200℃,and the inorganic heat-resistant additives absorbed heat and the methyl and phenyl of the organic heat-resistant additives decomposed that prevented the fiber thermal degradation.


This paper presents the results of technological studies of two samples of gold-bearing ore from the gold-bearing deposit of Kazakhstan deposits 1 and 2. A comprehensive analysis of ore samples by X-ray fluorescence, X-ray phase, chemical, and mineralogical methods was carried out. The calculated initial gold content was determined, and X-ray fluorescence analysis showed that the main elements that make up the ore are oxygen up to 51% and silicon up to 33%. X-ray phase analysis showed the presence of more than 95% quartz and muscovite in the samples. The form of finding gold in the ore, according to the results of mineralogical analysis, is defined as free gold and gold in iron hydroxide. Silver is present in the studied samples in the form of various types of halides. An ore beneficiation scheme has been developed and presented, including gravity and flotation. Gravity enrichment was carried out in two stages, with the production of concentrate and tailings, with the maximum recovery of gold in concentrate up to 91%, flotation enrichment using butyl xanthate reagents and a blowing agent, was carried out in two stages with the production of main and control concentrates and final flotation tailings. The subsequent hydrometallurgical study of the ore was carried out to assess the effect of sodium cyanide on the extraction of gold, tests were performed on the leaching of the initial samples of the ore and the obtained flotation and gravity concentrates in the agitation mode, it was found that cyanide leaching is an effective method for processing the mineral raw materials of the gold-bearing deposit of Kazakhstan, and the obtained flotation concentrates, with the recovery of gold into solution under optimal conditions up to 98%. The results obtained make it possible to predict the effectiveness of the main technological stages in the ore processing scheme, technology optimization, and maximum gold recovery.


Abstract Aim Biodiversity monitoring and conservation are extremely complex, and surrogate taxa may represent proxies to test methods and solutions. However, cross-taxon correlations in species diversity (i.e., cross-taxon congruence) may vary widely with spatial scale. Our goal is to assess how cross-taxon congruence varies with spatial scale in European temperate forests. We expect that congruence in species diversity increases when shifting from fine to coarse spatial scales, with differences between species richness and composition, and across pairs of taxonomic groups. Location European temperate forests. Time period Present. Major taxa studied Vascular plants, bryophytes, birds, epiphytic lichens, saproxylic beetles and wood-inhabiting fungi. Methods We used field data (354 plots across 23 sites) encompassing Italy, France and Hungary, with species information for six taxonomic groups. We accounted separately for spatial grain (the size of elementary sampling unit) and extent (the geographical area included in the survey) and evaluated the relationships within all the possible pairs of taxa. Results Although no pair of taxa had its species richness consistently correlated across scales, we found no changes in the direction of correlations when analysing species composition. However, when increasing grain and extent, we did find a general increase in the magnitude of correlations in species composition and partial changes in significance, with plants having the highest number of significant correlations. Main conclusions Species richness congruence among taxa is strongly scale dependent owing to differences in the relative contribution of large- and small-scale processes across taxa. Cross-taxon congruence in species composition is scale dependent only for its magnitude, because life-history traits of individual species make responses to environmental factors similar across scales. Forest monitoring should consider multi-taxon sampling and limit the use of surrogates at specific spatial scales, especially for species richness. Sampling plant species composition in scattered plots across different sites may effectively summarize the whole community composition.


The main aim of this work is to design a compact Rectangular shaped Multislot patch antenna for Ultra Wide Band (UWB) and X band applications. The proposed antenna has a condensed size of 35*30*1.6mm3 . The antenna consists of a rectangular patch with microstrip line feed etched on FR4-epoxy substrate with dielectric constant of 4.4. To improve the bandwidth, circular slots are made in patch and the ground plane. The proposed antenna achieves wide bandwidth of 12.7GHz (3.3-16 GHz) having four resonance frequency with good return loss and maximum gain of 9.64dBi. The antenna is designed, simulated and analyzed by using HFSS (High Frequency Structural Simulator). The charisma of this design is that it employs single patch that makes it easy to fabricate and cost-effective as well.


Localization and navigation of mobile robots precisely in an indoor environment is one of most important and challenging tasks. Navigation using conventional approaches such as Global Positioning System (GPS) and some vision based odometry are not very much effective in indoor environments. Therefore, a magnetic wheel encoding mechanism was selected in order to improve the navigational method. Also it could be with the most common localization approaches such as GPS, inertial navigation systems and laser sensors. This paper discusses a mobile robot application which navigates using magnetic wheel encoders and camera sensor. Further, the robot uses Wi-Fi to gather information and it creates intelligence to find the path dynamically. The Central control center and its main database process all available data and send the relevant control commands to the robots. Additionally, it will direct the messages between the nodes and the robot and keep robots on the correct track. The environment that the robot is moving is a pulse of black lines in white background. For the detection of the line Hough transformation has been used. It is having the capability of detecting sensor nodes using Radio-frequency identification (RFID) or Quick Response (QR) codes and taking measurements and returning to the base station avoiding obstacles communicating between nodes and the base.


The relationships between fire auto alarm systems and intelligent buildings are outlined in this paper.This paper also discusses the reasons,the designing methods,the communication protocols of the intelligent buildings' fire auto alarm systems.


The article deals with the process of modeling the system innovation in the training of educational managers at a university. The authors analyze the strategic management innovation, which provides high quality of specialists' training that meets international standards.


Oils that show signs of oxidation and biodegredation have been recognized in the sub-salt sediments of the South Emba Late Paleozoic high and monocline, Karaton-Prorva zone of highs, Arman-Yelemes zone of subsidence, and Zharkamys-Yenbek zone of arch highs. See figure 1. The main criteria for recognizing this alteration are infrared spectrographic signatures. The zone of paleo-alteration of oils coincides with the limit of pre-Permian regional erosion. Oils that formed in regions of crypto-alteration are distinctive of a zone of pinchout of carbonates on the east. Indicative of weak alteration in pools is the appearance of small naphthene "bumps" on the chromatograms of higher alkanes and isoprenoids of oils of the Zharkamys-Yenbek zone of arch highs. The total discharge of light hydrocarbons and ratios of hydrocarbons in benzine fractions indicate that the Lower Permian oils of the Urtatau-Sarybulak, Ushmola, and Shol'kara areas on the South Emba arch have a migrational component, and almost everywhere on the Zharkamys-Yenbek arch (Zhanazhol, Kenkiyak, Urikhtau, and others) hydrocarbons have flowed upward from Carboniferous into Lower Permian sediments.


Variance,genetic correlation and system cluster of 13 characters of 96 upland cotton genotypes were analysed. The results showed that there was a significant differences in genotypes and different genetic correlation in characters. There are strong correlation in yield characters. Yield had little correlation with fiber characters, especially with fiber strength.The 96 genotypes were grouped into five genetic clusters. The fourth genetic cluster gives higher yield and fiber quality, some of them could be selected as high fiber quality parents. [WT5HZ]


The sensor community has long been presented with the problem of prioritizing among several competing sensor system variables due to the inability to produce a high confidence, low-cost, reliable, and compact device. Typically a solution for very critical scenarios has been a high-cost scale reduction of larger more laboratory based instrumentation. This often produces data on a single parameter that is beyond reproach, however this can also produce a very delicate, bulky, and costly system often requiring a vacuum system or some sort. An alternative approach involves using micro-electro-mechanical systems based sensors.


Hildebrand's "Alexander" is a compilation fo mostly humanist chronicles and stories about Alexander the Great, whose main sources are Johannes Aventin's "Baierische Chronik" and Johann Hartlieb's "Alexander". The combination of these two elements is extraordinary, given Aventin's philological criticism of Hartlieb. Secondary sources are Plutarch's "Vitae parallelae" and Johann Carion's "Chronica" (both probably in German translations); and Hartmann Schedel's "Weltchronik". Hildebrand's characterization of Alexander particularly ambivalent, his depiction balanced between a tyrant and a peaceful emperor ruling for the ordinary people. This life of Alexander gives an important role to the ancient Germans, and so the narrative provides a story of the German nation as well, confronting humanist approaches to the nation with older concepts of "translatio imperii" and "imperium"


Combined with several years' experiences in construction,the construction technology of ground source heat pumps system is summarized.In view of the quality questions caused by improper construction corresponding resolving methods are proposed,in order to really realize high efficiency,energy saving and environmental protection targets for ground source heat pumps system.


Lithium salts are being used increasingly to treat patient with affective disorders, especially acute mania, or bipolar manic-depressive illness. For therapeutic effect the lithium content must be maintained at or above a particular level. Lithium poisoning due to overdosage may be seen occasionally, and its course is determined primarily by the rate of renal lithium elimination. A search is therefore indicated for procedures that could raise the lithium clearance. In a number of reports renal lithium excretion has been studied in relation to the excretion of water, sodium, potassium and hydrogen, but effects of sodium or water on the lithium excretion has not yet been clarified. Hence the present study was undertaken to investigate the effects of corticosteroid on the excretion of lithium ion. The female rat(Sprague-Dowley), weighing from 200 to 300g, was injected with 50mg/kg of lithium chloride intraperitoneally, and then injected with graded dosage of fludrocortisone and dexamethasone in each group. During the injected rats were incubated in metabolic cage, 24 hour urine of rats were collected. At 24 hours after injection, the rats were sacrificed with guillotin, the blood were collected. And then the concentratios of , , of collected urine and serum were checked by Flame photometer. The results are summarized as follows; 1. Fludrocortisone decreased the serum concentration of lithium and increased the urinary excretion of lithium. 2. In the group treated with low dose of dexamethasone(0.1mg/kg), the serum concentration of lithium was decreased and high dose of dexamethasone (1mg/kg) increased the urinary excretion of lithium. 3. Fludrocortisone increased the urinary in serum and decreased in urine, but opposite effects were occurred in dexamethasone. By above results, it may be concluded that corticosteroid increased the urinary excretion of lithium and decreased the serum concentration of lithium, but it seems to be there is no relationship between these effects of corticosteroid and of the renal or transport.


proposition of segregation or detection, which would probably need a specialist interview. ii. An order or a threat that re-infection would lead to penal segregation would encourage concealment. iii. Men who were occasionally promiscuous in the strict sense made up nearly two-thirds of the V. D. patients. The external events which usually lead to such acts are not of a nature which can be controlled from within the Army. Nevertheless, the acute emotional disturbance which prompts promiscuity in these men could in many cases be reduced below the danger point by effective man-management or by the provision of a certain type of recreational atmosphere which could, on this important occasion, compete with what is felt to be the warmth and geniality of the "pub." iv. The nature and motives of the completely promiscuous, non-professional consort seem to represent a field of investigation which might yield a profit. The problem of such women is not likely to be solved by education. As in the case of the habitually promiscuous man, it is likely to be based on personality and such facts as being unaware of infection. v. Since promiscuity of the types which lead to V. D. is seldom the result of positive mature sexual interest but mainly the result of attempts to relieve acute psychological stress, neither punishment on the one hand nor evil counsel on the other is likely to affect to any marked degree the incidence of such promiscuity. vi. More precisely, increased propaganda favouring prophylaxis of infection by condom and by chemical methods is unlikely to increase the promiscuity which leads to V. D. vii. Propaganda and education with regard to V. D. should primarily take into account three important points:


Electrokinetic phenomena and remediation characteristics observed during the experimental application of an electrokinetic remediation technique for unsaturated soils contaminated by heavy metals were analyzed. Series of column tests were run in the laboratory at varying degrees of saturation for shooting range soils. The result indicates that lead (Pb) was removed under unsaturated conditions primarily by electromigration within a diffuse double layer. If the initial contaminant concentration was below the cation exchange capacity and equal to the adsorption per unit soil solid weight, the remedial efficiency decreased with decreasing transport efficiency due to changes in the degree of saturation in the electric gradient of 1 V/cm.


The authors performed a two-stage quantitative trait loci (QTL) analysis of the prepulse inhibition (PPI) phenotype in 1,010 mice derived from crossing the high PPI strain C57BL/6 with the low PPI strain C3H/He. PPI is a reflection of sensory motor gating mechanisms within the central nervous system and is typically diminished in human schizophrenia. Ten loci for PPI were identified, six for the acoustic startle response, and four for latency to response peak, some of which were sex-dependent. A promising candidate on the chromosome 10-QTL was Fabp7 (fatty acid binding protein 7), a chaperon for the essential fatty acid docosahexaenoic acid (DHA), highly expressed in astrocytes and with functional links to the N-methyl-D-aspartic acid (NMDA) receptor. Fabp7-deficient mice showed attenuated neurogenesis, decreased PPI and a short startle response latency. Fabp7-transcript expression is up-regulated in schizophrenic brains, and a genetic study with 570 schizophrenic Japanese patients and 570 controls shows a modest but significant association with a missense polymorphism (182 C>T, Ther61Met) in males (odds ratio = 1.85). On the basis of structural modeling, the replacement of Thr by Met may be causing an increase in hydrophobicity and breakage of a hydrogen bond releasing a water molecule. These changes may affect protein stability or the affinity for fatty acids. On the other hand, the effect of Fabp7 on mouse PPI cannot be solely due to the same mutation, because there are no amino acid differences between C57BL/6 and C3H/He mice. The authors propose that replenishment of DHA in pregnant mothers can be beneficial in reducing the chance of schizophrenia development in their offspring, especially for high-risk families carrying the Ther61Met substitution.


BELGRADE, SERBIA 2018 3rd International Meeting on Materials Science for Energy Related Applications held on September 25-26, 2018 at the University of Belgrade, Faculty of Physical Chemistry, Belgrade, Serbia is a satellite event of PHYSICAL CHEMISTRY 2018 14th International Conference on Fundamental and Applied Aspects of Physical Chemistry


It has become commonplace in contemporary discussions of Arkansas politics to make certain intrastate or regional distinctions. For example, based on the evidence of the last decade's statewide and substrate elections, Republican candidates are more likely to find favor in northwest Arkansas than in southeast Arkansas. Drawing on everything from legislative positions on the Equal Rights Amendment and creation science bill to advertisements in the Arkansas Times, it is widely assumed that values and attitudes are more progressive in the densely-populated, more urban and sophisticated central region than in the sparsely-populated, more rural and provincial hills and lowlands. The considerable Black population in eastern and southern Arkansas presumably skews political opinions and judgments in one direction, while the increasing numbers of midwestern migrants into northern and western Arkansas presumably have a distinctive and dissimilar political impact.


Some methodological aspects of the rapid ACTH stimulation test (RST) and the prolonged ACTH stimulation test (PST) remain heterogeneous, e.g. administration routes, time of the day, duration, interpretation criteria and clinical indications. To standardize both tests we studied the serum cortisol responses to ACTH in 16 normal subjects, 16 patients with Addison's disease (AD), 14 with hypopituitarism (HP) of different etiologies and 13 patients on chronic glucocorticoid (CG) treatment (doses equivalent to 5-20 mg/d of prednisone for at least 6 months). For the RST, 250mcg of Cortrosina Organon were injected as an IV bolus and blood collected before and 60 minutes later, whereas for the PST, 250mcg of Cortrosina-Depot Organon were injected IM, every 8 hours for 3 days, and blood drawn daily between 8 and 9 o'clock AM. The post-ACTH cortisol value was the single parameter chosen to interpret both tests (the absolute or percent increase was of no further value). The 95% lower confidence limits (mean minus 1.64 SD) for the RST and the 3rd day of PST were 19.1 and 49.0mcg/dL, respectively. AD patients did not increase cortisol in response to both the RST (1.1 +/- 1.2 to 1.2 +/- 1.1mcg/dL) or the PST (1.2 +/- 1.3 to 2.0 +/- 1.7mcg/dL). However, whereas 22 out of 27 patients with HP and CG showed a modest cortisol increase to the RST (1.6 +/- 2.3 to 5.6 +/- 4.7 mcg/dL), all had a gradual and nearly normal response on the 3rd day of the PST (1.6 +/- 2.1 to 29.6 +/- 16.6mcg/dL).(ABSTRACT TRUNCATED AT 250 WORDS)


Cooperative radar operations typically rely on the exchange of a limited amount of information to improve the quality of the estimated targets parameters. Unfortunately, in many instances, not all necessary information can be accessed or communicated, e.g., no line of sight (LOS) or limited resources. This problem is exacerbated with the inset of novel (irregular) waveforms, exhibiting large number of degrees of freedom, on transmit. For example, where both monostatic and bistatic measurements are available, enhanced parameter estimation can be achieved through sharing only the synchronization and geographical information between two platforms. In this paper, we focus on this scenario and derive the Cramer- Rao lower bound for the estimation of the unknown bistatic waveform under no-LOS mild assumptions on the second-order statistic of the bistatic and monostatic returns. Also, we devise a set of algorithms exploiting the monostatic estimated scene, based on spectral methods, factor analysis and calibration techniques. Through numerical experiments, we compare the performance and discuss the limitations of the introduced techniques.


Introduction. Construction science always seeks to save materials, including in the design of steel frameworks. Currently, in modern construction standards, structural analysis of frameworks for industrial buildings, namely their columns, is carried out without considering the stiffness of the crane girder which receives the load from the overhead crane. However, this factor can give a certain economy of metal, since the stiffness of crane structures directly affects the stability of columns of industrial buildings, and therefore the metal consumption of the framework.Aim. To achieve savings of steel due to taking into account the effect of crane girder stiffness on the stability of an industrial building framework.Materials and methods. For these purposes, the authors of the paper used classical methods of structural mechanics. A programmed cyclic algorithm of the Mathcad software was used to find the critical forces and effective length coefficients at various stiffnesses of the column elements. Columns of an industrial building are usually two-member. Given that, its structural design is twice statically indeterminate by the deflection method. The bearing capacity of an industrial building column is found by deriving the critical force, which is determined from the equation obtained by setting equal to zero the stability determinant consisting of the coefficients of the linear equation system by the deflection method. In addition, the effective length coefficient for the upper and lower parts of the column is determined. The paper compares the results obtained with the scheme without taking into account the crane girder.Results. Considering the effect of the crane girder stiffness enabled the material consumption of the column to be reduced by 30 %. Critical forces and effective length coefficients were found at various stiffnesses of the column elements, using a programmed cyclic algorithm of the Mathcad software.Conclusion. Taking into account the stiffness in the structures of the elements in the industrial building frameworks reduces metal consumption.


Intersections are the key nodes in an urban traffic network that affect overall traffic efficiency. Lane width is a major element of an intersection that is affected by the saturation flow rate of the intersection. It is also influenced by a variety of other factors, such as road resource constraints, vehicle composition, traffic safety, and driving comfort. To determine the appropriate lane width, this study analysed relationships between lane widths and design-related factors, including saturation flow rate, lateral safety distance, traffic crash rate, and driver comfort. First, screening and surveys were conducted using the design data of more than 3000 existing crossroads. Then, seven intersections with different lane widths were selected. To collect traffic flow data, video-based surveys were conducted. Meanwhile, the traffic crash rate was collected to assess traffic safety. Moreover, surveys were conducted to assess the driving experience. Finally, the Delphi method was developed to evaluate the index weights of the design-related factors. The case study revealed that the optimal lane width for four-legged intersections is 3.1 m. A lane width of 2.8 m is an alternative for cases of limited road resources. The results could be supplementary guidance or reference for road designers and administrators.


The future wireless networks, such as Centralized Radio Access Network (C-RAN), will need to deliver data rate about 100 times to 1000 times the current 4G technology. For C-RAN based network architecture, there is a pressing need for tremendous enhancement of the effective data rate of the Common Public Radio Interface (CPRI). Compression of CPRI data is one of the potential enhancements. We introduce a vector quantization based compression algorithm for CPRI links, utilizing Lloyd algorithm. Methods to vectorize the I/Q samples and enhanced initialization of Lloyd algorithm for codebook training are investigated for improved performance. Multi-stage vector quantization is considered to reduce codebook search complexity. Simulation results show that our solution can achieve compression of 4 times for uplink and 4.5 times for downlink, within 2% Error Vector Magnitude (EVM) distortion. Remarkably, vector quantization codebook proves to be quite robust against data modulation mismatch, fading, signal-to-noise (SNR) and Doppler spread.


In this research paper a rotor which serves as a rotating structure is driven by a 4KW alternating current motor through couplings which is suspended byan active magnetic bearingwith its position Sensors and Hall Effect Sensors connected in place which are finally connected to a main computer. A digital link which interface between the DSP and the general mathematics program is made to run on computer in which all the forces and the displacement signals are available in analog whichthen processed and finally display the results. Natural frequencies and mode shapes were used for predicting dynamic behaviors of rotor model, in determing this the free-free system were assumed without putting the bearings in operation and then subsequently the rotational speed was set, the first three natural frequencies of the system without rigid modes with its corresponding values was used as the process and stages observability and controllability of the rotor system during the experiment and the analysis process. Modal analysis was then performed for the freefree boundary conditions for the rotor system with bearing conditions when the rotor speed was equal to 20000rpm. The structure under investigation was established with a measured model input-output impulse response functions and the results studied and discussed.


] Objective To analyze the clinical features of patients with macrophage activation syndrome (MAS) complicating adult onset Still's disease (AOSD). Methods The clinical data of four patients diagnosed with MAS and AOSD in our department from May 2008 to Jan 2011 were reviewed and summarized. Results One case occurred during the onset of AOSD and during the relapse in the rest of cases. The main symptoms were persistent fever (n=4), rash (n=2, arthritis(n=2), lymphoadenopathy(n=2), splenomegaly(n=3), heptomegaly(n=1), hematocytopenia(n=4), abnormal liver function tests(n=3), increased serum triglyceride level(n=3), decreased serum fibrinogen level(n=2), and haemophagocytosis in bone marrow analysis (n=4). Three patients' treatment regimen were comprised of methylprednisone and cyclosporine. Cyclosporine was replaced by mycophenolate mofetil in one patient. All patients achieved remissions. Conclusion MAS should be evoked in AOSD complicated with persistent fever, hematocytopenia, high serum level of triglyceride and lactate dehydrogenase and low serum level of fibrinogen. Haemophagocytosis in the bone marrow is important for differential diagnosis. Corticosteroid, cyclosporine and mycophenolate mofetil are effective in this situation.


In the Karasawa cirque (36°17'N, 137°40'E) of the Hotaka massif, observations of the perennial snow patch, especially its size, were taken from 1968 to 1976. The size at the end of every ablation season ranged from 104 to 105 m2, and its average was 5.7 × 104 m2. Snow ablation from May 3 to October 10, 1976, is about 12.5 m in snow depth. The snow patch consists of two parts : the stratified layers due to snow falls, in which several ice layers are found, and disturbed layers due to debris of avalanche.


Objective The purpose of this study was to compare different ways on radial artery cannulation in patients undergoing routine or emergency surgery to seek optimal teaching methods.Methods Many patients undergoing major surgery,who required a radial artery catheter,were included in the study.Patients and interns were divided into 3 groups: control group with VasocanR BraunuleR remaining needle;Group A with ARROW flash dedicated artery cannulation needle;Group B with 1ml injector-assisted improved needle.Then we compare the success rates in different groups.Results Success rate of group B was higher than others from 0 to 2nd months.Success rate of group A was lower than others and there was no significant difference between group B and control group each other from 2nd to 6th months.Conclusion The 1ml injector-as-sisted technique could improve the success rates of radial artery cannulation and was also the ideal clinical teaching methods.


To evaluate the response in patients undergoing SBRT using dynamic contrast‐enhanced (DCE) integrated magnetic resonance positron emission tomography (MR‐PET). Stereotactic body radiation therapy (SBRT) is efficacious as a front‐line local treatment for non‐small cell lung cancer (NSCLC).


The present study aimed to explore whether personality traits infl uence buying behaviour and if this infl uence differs depending on a different culture. The author focused on a crosscultural investigation of Poland and the UK. Data were collected via an online questionnaire which measured personality traits, consumer purchase behaviour and the meaning of branded products for 525 participants. The results show signifi cant relationships between personality traits and both, consumer shopping styles and the way individuals perceived branded products. Personality traits were assessed by the MINI-IPIP test, a 20-items instrument which measures the Big Five personalities: Extraversion, Agreeableness, Conscientiousness, Neuroticism, and Intellect/Imagination (or Openness). Buying behaviour was tested by two scales. The fi rst one was a 39-item Consumer Shopping Inventory (CSI), which indentifi es eight shopping style dimensions: Perfectionist/High Quality Conscious, Brand Consciousness/Price Equals Quality, Novelty and Fashion Conscious, Recreational and Shopping Conscious, Price Conscious/Value for the Money, Impulsiveness/Careless, Confused by Overchoice, Habitual/Brand Loyal. Another instrument used was a 32-item the Meaning of Branded Products scale, presenting four dominant themes: Quality, Values, Personal Identity and Traditions. The present study also investigated the moderating effect of citizenship and other socio-demographic characteristics in the relation between personality traits and both, the meaning of branded products and shopping styles. JEL classifi cation: M5, D7


This note suggests that the behavior of stock-market prices may be modelled by using a stochastic differential equation given the interpretation due to Ito rather than that of ordinary calculus. The workings of the stock market are shown to conform intuitively to this interpretation; an important conclusion is that the observed rise in stock prices can be attributed to deterministic effects. Under ordinary calculus this rise can be explained as due to purely random disturbances.


The invention discloses a beef freshness detection device and detection method, the beef freshness detection device includes an opaque casing, a controller, a laser array, a spectrometer, a light intensity adjusting device, a rectangular container which is arranged in the casing and is provided with an opening on the upper end, a rectangular sample tray arranged in the container, a bracket arranged on a base plate of the casing, a light emitting head which is arranged on the bracket and used for irradiating light to a sample, and a light receiving head used for receiving reflected light of the sample; the light intensity adjusting device, the laser array and the light emitting head are orderly electrically connected, the light receiving head and the spectrometer are electrically connected, the container and the sample tray are made of a magnetic-impermeable material, the container is provided with a liquid, the sample tray is suspended above the liquid surface, a plurality of vertical holes of m order matrix arrangement are arranged on the bottom of the container, and the beef freshness detection device has the advantages of fast detection speed; more point detection, reliable detection data and higher precision.


Objective To evaluate application of Blue on Yellow Perimetry(BYP)and Standard Au-tomatic Perimerty(SAP)in the diagnosis of primary open angle glaucoma(POAG)patients.Methods A total of 72 patients (120 eyes)diagnosed POAG were enrolled for SAP and BYP examination.There were 26 females (44 eyes)and 46 males (76 eyes).50 left eyes, 70 Right eyes.Mean (SD)age of the patients was 43.87(17.53) years(range, 16-79 years).All patients were both examined blue on yellow with FASTPAC and SAP with SITA Standard strategy separately,using the Humphrey Field Analyzer 750 Ⅱ-i and Program 30-2.Results In the early period POAG patients,BYP compared SAP with the scope of defect was usually increased,deeper and wider.In the moderate POAG patients,BYP could detect some defects that SAP could not,and showed the same defect depth as SAP.In the advanced period the ability of BYP to reflect the visual field damage is as same as SAP.In visual field index for the diagnosis of contributions,the defect points are with the best diagnos-tic value.Conclusions BYP should be more suitable for the screening of POAG suspected.When extensive vi-sual field damage occurred, the diagnostic capability of BYP was equal to SAP.

Key words:
BYP;  Visual field;  Glaucoma


Patrick Braden, also called as 'Kitten' in the film Breakfast in Pluto, was a male-to-female transgender who lived in small town of Tyrellin, Ireland. He longed for his biological mother and to serve his purpose, in 1970s, he moved to London to search her love. During serving his purpose, he was establishing himself to perform his opposite gender. Judith Butler's gender performativity was the theory applied in order to explore how Patrick performed his gender. Qualitative method was conducted by selecting the scenes from their narrative and non-narrative aspects. The finding from the analysis on storyline, costumes, make-up, performance, and color was that he kept repeating imitating the appearance of a woman by wearing woman's clothes and applying nail polish. Furthermore, the imitation was followed by another feminine skill such as sewing. The repetition done by Patrick showed that he performed the opposite gender performance.


Bleeding from oesophageal varices is one of the most dramatic, urgent, frightening, and life threatening events for a patient. Its swift and accurate diagnosis and confident and effective management remain one of the most challenging clinical exercises in medicine. The diagnosis having been made, what is the method of choice for arresting the bleeding-and minimising the chances of recurrence? Firstly, we have available two temporary measures to control immediate bleeding-intravenous administration of vasopressin and the Sengstaken-Blakemore tube. Either may help to bring the escape ofblood under control-buying time for a more definitive attack on the varices with the patient more stable. Secondly, we have five procedures with more lasting effect: one or other form of portasystemic shunt; transaction of the oesophagogastric junction with reanastomosis; direct ligation of the varices through an abdominal or thoracic approach; porta-azygous disconnection using one of the circular stapling devices; or endoscopic variceal sclerotherapy. The order of listing of these procedures more or less reflects the chronological order in which they were introduced and found favour. Currently most debate seems to centre on the relative merits of the last two. The main reason for the considerable reduction in the number of portacaval shunts for bleeding varices has been the high risk of immediate mortality and serious morbidity, notably encephalopathy. Furthermore, the theoretical advantage ofpermanent reduction in the pressure in the veins at risk is more than offset by the price in other sequelae, particularly in patients with evidence of severe liver damage. Shunts may still be seriously considered in those with reasonable results of liver function-and the more proximal selective patterns of shunt (for example, that introduced by Warren) are more likely to have reasonable results. The other direct surgical approaches to the varices have the simple objective of interrupting the link between the portal system, with its raised pressure, and the low pressure systemic tributaries around the lower oesophagus. None of these procedures do anything to reduce portal pressure permanently, and the anxiety is, therefore, that further anastomotic connections will develop and that bleeding will recur. The disillusionment with shunting is such, however, that surgeons are now concentrating on critical evaluation of these simpler direct procedures on the varices. We learnt with the shunts how much the outcome depended on the state of the liver damage; so it is no great surprise for us now


Iris is a kind of perennial herbaCCUS flowers and plants belong to Iridaceae. They had been introduced by us since 1962. The results of domestication experimentation have indicated that most of Iris cultivated in natural condition in Van can pass their individual developmental stages and grow well. Irises are regarded as a promising flowers and plants. Because of their pe-ctihar appearance and bright colors they have been used in city greening,decoration to flowerbed,roadside and grassland in recent years. The types of introduced irises,biological and ecological characteristics,cultivation techniques and the value in landscape are reported in this paper.


ABSTRACT The population of English learners (ELs) continues to grow in schools across the United States and around the world. In this article, we share one urban university's collaborative approach to building educational capacity for cultural and linguistic diversity through professional development efforts that brought together stakeholders from classrooms, schools, communities, and districts. This grant-funded project aimed to build educator expertise to effectively support and positively influence students' language development and disciplinary learning. Grounded in sociocultural theory, we used an apprenticeship framework of teacher development, strategically planning and implementing collaborative capacity building efforts to foster learning across individual, interpersonal, and institutional planes. In this paper, we share the results of professional development efforts across three years of this project, drawing from observation, interview, and focus group data. Findings indicate that classroom-, school-, and district-level educators developed knowledge of discipline-specific language development, pedagogical skills for effective EL teaching and learning, and leadership abilities to positively shape institutional responses to their culturally and linguistically diverse student populations. Implications focus on fostering teacher professionalism through bottom-up development of EL-specific expertise and expanded opportunities for leadership.


On the condition that the new curriculum is implemented, Inquiry Learning is a hot problem. But why isn't the real implement of Inquiry Learning favoring? The article will probe into the essence of Inquiry Learning, the character of Inquiry Learning, and analyzes reasons of the background by the angle of culture comparison. Mostly it discusses the social culture system, the relation of teachers and students, the thinking mode of Inquiry Learning.


Formic acid (FA) is a promising reservoir for hydrogen storage and distribution. Its dehydrogenation releases CO2 as a by-product, which limits its practical application. A proof of concept for a bio-catalytic system that simultaneously combines the dehydrogenation of formic acid for H2, in-situ capture of CO2 and its re-hydrogenation to reform formic acid is demonstrated. Enzymatic reactions catalyzed by carbonic anhydrase (CA) and formate dehydrogenase (FDH) under ambient condition are applied for in-situ CO2 capture and re-hydrogenation, respectively, to develop a sustainable system. Continuous production of FA from stripped CO2 was achieved at a rate of 40% using FDH combined with sustainable co-factor regeneration achieved by electrochemistry. In this study, the complete cycle of FA dehydrogenation, CO2 capture, and re-hydrogenation of CO2 to FA has been demonstrated in a single system. The proposed bio-catalytic system has the potential to reduce emissions of CO2 during H2 production from FA by effectively using it to recycle FA for continuous energy supply.


Osteopontin (OPN) is a cytokine and ligand for multiple members of the integrin family. OPN undergoes the in vivo polymerization catalyzed by cross-linking enzyme transglutaminase 2, which consequently increases the bioactivity through enhanced interaction with integrins. The integrin α9β1, highly expressed on neutrophils, binds to the sequence SVVYGLR only after intact OPN is cleaved by thrombin. The SVVYGLR sequence appears to be cryptic in intact OPN because α9β1 does not recognize intact OPN. Because transglutaminase 2-catalyzed polymers change their physical and chemical properties, we hypothesized that the SVVYGLR site might also be exposed on polymeric OPN. As expected, α9β1 turned into a receptor for polymeric OPN, a result obtained by cell adhesion and migration assays with α9-transfected cells and by detection of direct binding of recombinant soluble α9β1 with colorimetry and surface plasmon resonance analysis. Because the N-terminal fragment of thrombin-cleaved OPN, a ligand for α9β1, has been reported to attract neutrophils, we next examined migration of neutrophils to polymeric OPN using time-lapse microscopy. Polymeric OPN showed potent neutrophil chemotactic activity, which was clearly inhibited by anti-α9β1 antibody. Unexpectedly, mutagenesis studies showed that α9β1 bound to polymeric OPN independently of the SVVYGLR sequence, and further, SVVYGLR sequence of polymeric OPN was cryptic because SVVYGLR-specific antibody did not recognize polymeric OPN. These results demonstrate that polymerization of OPN generates a novel α9β1-binding site and that the interaction of this site with the α9β1 integrin is critical to the neutrophil chemotaxis induced by polymeric OPN.


Difunctional methacrylate monomers having a hemiacetal ester moiety in the molecule were used to prepare a plastic replica of an original mold for imprint lithography. UV curing of the monomers was performed with 365 nm light and photo-induced degradation of the cured resins was performed using 254 nm light.


This paperanalyzesthepublic opinionin Europerelated to terrorism. Paper argues that public opinion on terrorism has always beenlinkedas an actbyextremistsand radicalIslamicgroups. Therefore, it creates blind spots on the development of other extremist groups to launch terorrist attact. Borrowingopinion from Kundnani(2012), paper adds thatpublic opinion is constructed by media response, key political figures' statements, and security narratives in Europe. In addition, paper analyzes massacre in Norway in 2011. Breivik, the perpetrator, was a right-wing Christian fundamentalist. Thus, supposed that since he wasn't a Muslim, the incident wasn't terrorism.


Time‐dependent intensities of the spectral lines emitted by laser‐induced plasmas generated in several gases are presented. The time‐resolved and spatially varying intensities of two once‐ionized nitrogen lines were used to calculate radial temperature distribution of temperature within the plasma. A modified blast wave theory, in which ionization was included through the Saha equation and the equation of conservation of charge, was used to calculate time‐dependent intensities of several spectral lines of C, N, He, and Ar. The temporal profiles of the spectral lines appear to be dependent on the ionization potentials of the species in the plasma.


A methodology for meeting the tight constraints in the physical realization of functional blocks for digital hearing aids was applied to the implementation of a noise reduction system based on lattice structures. This methodology fully exploits the fle xibility of custom VLSI design through a good interrelation among all the steps of the design. The emphasis was placed in the study of the fix ed point quantization effects to find the minimum number of bits and scaling required at every point of the algorithm. Based on these results, an estimation of the po wer consumption and required sil- icon area was done in the case of an implementation using a lo w power VLSI architecture.


A field experiment was conducted to investigate the soil physicochemical properties and N2 O emissions from brown soil amended with different materials by static chamber-gas chromatography method. Three treatments,including single fertilization( CK),fertilization and corn stover incorporation( CS) and fertilization and carbonized corn stover incorporation( BC) were set with the same rate of chemical fertilizer. The results showed that:( 1) The N2 O emissions of BC and CS decreased by 38.9% and 24.0% respectively,compared to CK.( 2) Compared with CS and CK,the N2 O emission intensity of BC decreased by 35.0% and 39.2% respectively,but no significant difference was observed between CS and CK.( 3) Both CS and BC decreased soil bulk density,ammonia oxidation potential,and increased soil p H,available potassium and organic carbon content.( 4) Correlation analysis showed that there was a significant positive correlation between N2 O emission and soil temperature,soil bulk density or ammonia oxidation potential. A significant negative correlation was found between N2 O emission and soil p H or nitrate nitrogen concentration. There was also a negative correlation between N2 O emission and soil organic carbon.


A Master of Arts Thesis in Translation and Interpreting (English/Arabic/English) by Hayyan Hamed A. Alrosan entitled, "The Subtitles of H. Dabbour: A Translational Dilemma." Thesis advisor is Dr. Ahmed Ali and was submitted in May 2012. Available are both hard and soft copies of the thesis.


The knowledge of geographical conditions is one of the main requirements for planning military operations at each command level. The natural environment enforces the variety of combat techniques. It is a truism, therefore, to say that every military historian reconstructing the course of wars or war campaigns should analyze the impact of natural conditions on the battle planning process and its course. The article presents the characteristics of Bulgarian area and the impact of geographical conditions on the course of military operations during the Russian-Turkish war of 1877–1878 and the Serbian-Bulgarian war of 1885. Although they were two different conflicts in terms of duration, number of forces and direction of conduct, their example shows the problems faced by fighting armies at the time. We are dealing with issues related to overcoming the swollen waters of Danube and battlefields abounding in hills and mountain passages difficult to access. Not without significance were weather issues, which influenced the course of the fight and the possibilities of supplying troops.


As sugars form complexes with boronic acids, some sugars are used as additives for boron-containing pharmaceuticals. The binding constants of the rare sugar D-allulose with boronic acids were measu...


As a main body of cognitive and practice,it's always a question to be focused and to be solved the contradiction between subject initiative and effect limitation.To achieve a higher level of freedom,subject must be analysised in a comprehensive and reasonable way.It is the key of the problem to find how to coordinate its initiative and limitedness through its development and derivation.


Radars can be used to observe persons. Animation of an observed human on the basis of Frequency Modulated Continuous Wave (FMCW) radar measurements in virtual reality considerably facilitates the interpretation of the radar measurements. These radar measurements give detailed information of the motion of the human body parts. The radar reflections are time-varying in range and Doppler. This information is used to animate a human in virtual reality. The delay between the observation and animation must be short for real-time applications. The paper describes a fast method for estimating human walking parameters from radar measurements and a simulated model. The parameters are estimated by minimizing the difference between a database with simulated model data and the real measurements. An approximation technique is used to estimate the essential walking parameters of the walking motion. The error with the exact solution is less than 10%. The computation time is less than the measurement time. This opens possibilities for real-time applications


This study report the optimal condition of an extraction method for caffeine residue analysis in water. C18 was impregnated with cellulose triacetate by using a solution casting method to produce a thin film. Optimization work was performed based on a 23-full factorial central composite design, which was subjected to salt addition, extraction time, and stirring rate as the main parameters. The optimum condition suggested by the model was as follows; salt addition (0.6 %, m/v), extraction time (11 min) and stirring rate (300 rpm). The generated model and 2-way interaction were significant at p < 0.05.
Detection and quantification limits of the developed method were calculated at 0.06 and 0.21 ng/mL, respectively. The thin film displayed exceptional recovery (83.90-98.50 %) and repeatability (7.71-12.40 % RSD) at two levels of concentration.


Introduction:
 Numerous clinical trials have been conducted in order to reduce or prevent the appearance of mucositis in patients undergoing cancer treatment and some of these have appeared in the clinical guidelines as recommendations (Keefe,DM Cancer 2007). However, to date no molecule has been shown to prevent appearance of this kind of lesions. Selenium, a trace element in the organism, cofactor of multiple biological processes, has been used previously for mucositis chemoprevention in head and neck tumors. We conducted a study to know if selenium supplementation has an impact on the development of mucositis.
 Objective:
 We aim to know the impact of Selenium in patients undergoing hematopoietic stem cell transplantation, in the presentation and duration of mucositis comparing against placebo.
 Methods: We performed a double blind clinical trial in a single center pilot study approved by our ethics committee. All patients candidates for autologous or allogeneic HSCT above 18 years were submitted for our study previous informed consent by our institution. Patients were randomized into one of two arms: a) selenium methionine, b) placebo.
 Previously randomized, patients were administered supplementation with oral selenium methionine at a dose of 400mcg/day or placebo starting 7 days prior transplantion. We determined a baseline measurement of serum and urinary selenium. Subsequent measurements were made each week for a total of 28 days. Evaluations were made with validated SMAQ questionnaires which also included scales of mucositis severity, using the WHO mucositis scale. All of them performed by an observer blinded to what supplementation were being administered to each patient.
 Results: We have recruited a total of 31 patients, of whom 16 were allogeneic and 15 autologous. We observed that 38.7% developed some degree of mucositis, most of them on the allogeneic arm (10 patients). Selenium consumption arm was associated with a median decrease of 32% (1.9 vs 2.8) in the WHO scale in the severity of mucositis compared to the placebo arm (p=0.046), however we didn't find difference in mucositis resolution time between groups (p=0.162). On the other hand, selenium supplementation was associated with shorter platelet engraftment time (p=0.041), without any significant difference in neutrophil engraftment time. With a follow up of 112 days, there are no difference about mortality or other analized variables.
 Conclusions: Supplementation with selenium was associated with a slight decrease in the severity of mucositis in comparison with placebo. Without any relevant findings in relation to mortality or other variables analized.

 Gomez-Almaguer: Novartis: Consultancy; AbbVie: Consultancy. Herrera-Rojas:Janssen: Employment.


Today, the world faces a major problem called population growth, one of the consequences of which is food shortages. Therefore, organic farming is considered as one of the most effective approaches to responding to the challenges facing human beings in realizing sustainable development. The purpose of this research is to provide a comprehensive model of branding for sensory marketing based on an interview with 20 experienced experts and marketing proficient, aspects of model and variables related to the use of MAXQDA software has been identified. Finally, based on the detected final criteria, the model is presented based on the data theory method. The results of open coding of the collected qualitative data using the interviewing tool showed that 86 open codes were identified among 331 concepts. Finally, 86 initial codes in the form of 18 categories of brand value, trust, brand awareness, marketing, brand image, knowledge and vision of production and development, risk, performance, cultural factors of consumption, financial factors, process, competitive advantage, socio-ecological responsibility, role of Government organizations, customer requirements, brand identity, customer loyalty, product attributes, are identified.