Low-cost particulate mass sensors provide opportunities to assess air quality at unprecedented spatial and temporal resolutions. Established traditional monitoring networks have limited spatial resolution and are frequently absent in 15 less-developed countries (e.g. in sub-Saharan Africa). Satellites provide snapshots of regional air pollution, but require ground-truthing. Low-cost monitors can supplement and extend data coverage from these sources worldwide, providing a better overall air quality picture. We demonstrate such a multi-source data integration using two case studies. First, in Pittsburgh, Pennsylvania, both traditional monitoring and dense low-cost sensor networks are present, and are compared with satellite aerosol optical depth (AOD) data from NASA's MODIS system. We assess the performance of linear conversion 20 factors for AOD to surface PM2.5 using both networks, and identify relative benefits provided by the denser low-cost sensor network. In particular, with 10 or more ground monitors in the city, there is a two-fold reduction in worst-case surface PM2.5 estimation mean absolute error compared to using only a single ground monitor. Second, in Rwanda, Malawi, and the Democratic Republic of the Congo, traditional ground-based monitoring is lacking and must be substituted with low-cost sensor data. Here, we assess the ability of regional-scale satellite retrievals and local-scale low-cost sensor measurements to 25 complement each other. In Rwanda, we find that combining local ground monitoring information with satellite data provides a 40% improvement (in terms of surface PM2.5 estimation accuracy) with respect to using ground monitoring data alone. Overall, we find that combining ground-based low-cost sensor and satellite data can improve and expand spatio-temporal air quality data coverage in both well-monitored and data-sparse regions. https://doi.org/10.5194/amt-2020-67 Preprint. Discussion started: 3 March 2020 c © Author(s) 2020. CC BY 4.0 License.


Complexes of 3\4\5\6!tetrahydro!4\6!dioxo!ð0\1\3Łtriazolo!ð0\4!aŁ pyrimidine "H1tpO1# with the divalent transition metals of the _rst transition series from Mn to Zn have been synthesized and characterized\ their general formula being M"HtpO1#1 = nH1O[ The crystal structure of the manganese compound\ ðMn"HtpO1#1"H1O#1Ł\ has been solved by single crystal X!ray di}raction\ showing that the ligand binds bidentately through the exocyclic oxygen O6 and the endocyclic nitrogen N0[ The deprotonation of the ligand takes place at the active methylene group at position 5\ as it happened in Na"HtpO1# = 1H1O\ and not at the N0H group at position 3[ Infrared data suggest that the ligand binds in a similar fashion in the Fe\ Co\ Ni and Zn compounds but not in the copper one[ This has been corroborated by powder X!ray di}raction\ which indicates that all compounds except Cu are isostructural[ Þ 0887 Elsevier Science Ltd[ All rights reserved Keywords] deprotonation ^ ligand ——————————————————————————————————————————————— Triazolopyrimidine derivatives are ligands that dis! play a great versatility in their interaction with metal ions\ not only because they can bind the metal atom through di}erent positions ð0Ł but also because their presence in~uence the behaviour of other auxiliary ligands\ either by electronic or steric reasons\ giving rise to compounds with interesting metal!to!metal interactions through these auxiliary ligands ð1Ł[ Nevertheless\ when the ligands act monodentately\ the preferred binding position appears to be the nitro! gen atom at position 2 ð2Ł "see diagram below for the numbering scheme#[ Polymeric compounds are usually obtained when N0 acts together with N2 ð3Ł whereas dimers with eight!member 0M0N0C0N0M0N0C0N0 rings are for! med when the binding mode is N2\N3 bidentate ð4Ł[ Author to whom correspondence should be addressed[ E!mail ] mpsansanÝgoliat[ugr[es 1366 Until now\ the study of the interaction of metal ions with these ligands has been mainly focused on those that are commercially available ] unsubstituted s!tri! azolo!ð0\4!aŁpyrimidine "tp#\ its derivative methylated at positions 4 and 6 "dmtp# and that with a methyl group at position 4 and an oxo group at position 6 "HmtpO#[ For the latter\ despite the presence of an oxygen atom\ N2 is still the primary binding site with only one example in which bidentate N0\O6 coor! dination is preferred ð5Ł[ Following this line of research\ we have recently reported the synthesis and characterization of a new triazolopyrimidine derivative\ 3\4\5\6!tetrahydro!4\6! dioxo!ð0\1\3Łtriazolo!ð0\4!aŁpyrimidine "H1tpO1# ð6Ł[ A diagram of this ligand\ together with the numbering scheme of the ring is shown over[ This compound has a very strongly acidic meth! ylene group at position 5\ which may confer inter! esting properties to it[ Molecular orbital calculations on its anion point to the oxygen atoms as the preferred S[ Orihuela et al[ 1367 binding sites ð6Ł\ the chelate O6\N0 possibly being the better choice[ This is experimentally demonstrated in this article\ in which the synthesis and characterization of metal complexes of the anion HtpO1 with the _rst transition divalent metals from Mn to Zn are reported[ The single crystal X!ray study of the Mn compound displays the expected N0\O6 bidentate behaviour\ this coordination mode being also strongly suggested for the other metals "Cu perhaps excepted# by the spec! troscopic studies and by the powder X!ray study[


Anagasta kuehniella is a polyphagous pest that causes economic losses worldwide. This species produces serine proteases as its major enzymes for protein digestion. In this study, a new serine-protease inhibitor was isolated from Acacia polyphylla seeds (AcKI).Further analysis revealed that AcKI is formed by two polypeptide chains with a relative molecular mass of ∼20 kDa. The effects of AcKI on the development, survival, and enzymatic activity of Anagasta kuehniella larvae were evaluated, by incorporating AcKI in an artificial diet. Bioassays revealed a reduction in larval weight of ∼50% with the lower concentration of AcKI used in the study (0.5%). Although additionalassays showed an increase in endogenous trypsin and chymotrypsin activities, with a degree of AcKI-insensivity, AcKI produces an anti nutritional effect on A. kuehniella, indicating AcKI as a promising bioinsecticide protein for engineering plants that are resistant to insect pests.


Objective To explore the application effect of concentrated multimedia-assisted visits to laparoscopic surgery.Methods A total of 452 subjects with elective laparoscopic surgery were randomly divided into observation group(with multimedia-assisted visits)and control group(with sound and photo visits).The questionnaires on anxiety,operation knowledge and satisfaction with visits were applied before and after visits.Results The scores on anxiety in the two groups were both decreased.The score on anxiety in the observation group was more significantly than that in the control group(P0.01).There were significant differences in the anxiety degree between pre-and post-visits in both groups(P0.01).There was significant difference between the two groups in contrast of pre-and post-visits in terms of surgical knowledge(P0.01),and the patient's satisfaction rate on preoperative visits in observation group was higher than that in the control group(P0.01).Conclusion Concentrated multimedia-assisted visits are effective in reducing anxiety of patients with laparoscopic surgery and improving the patients'general knowledge on the surgery and the satisfaction and frequence of preoperative visits,thus enhancing the nursing quality.


Patient immobilization by general volatile anesthesia (VA) during medical radiology treatment is sometimes necessary and annual trends are increasing. Ionizing radiation (IR) exposure is known to cause some level of DNA damage since IR is a well-known genotoxic and cytotoxic agent, although the doses used are kept to a minimum, with good localization in order to protect as much healthy tissue and organs as possible from exposure. Recently, a growing number of studies have demonstrated that volatile anesthetics can also cause DNA damage effects in patients, and in occupationally exposed personnel. Since there are no studies on the combined effects of IR and VA, we decided to use an animal model of Swiss albino mice to determine whether there are elevated levels of DNA damage after combined exposure by mimicking real conditions of exposure during radiology treatment. Healthy male mice (5 animals per group) were anaesthetized by inhaling 2.4% halothane for 2 hours and then were exposed to either 1 or 2 Gy of ionizing radiation (60Co source). Groups were examined immediately after exposure, and again after 2, 6 and 24 hours. Blood was taken from the tail, and liver after animal sacrifice. The study was approved by the Ethics Committee of the Faculty of Science, University of Zagreb, Croatia, and designed in accordance with the relevant Croatian guidelines (Animal Protection Act, Ordinance on the protection of animals used for scientific purposes). Duplicate samples were prepared for the alkaline comet assay, and DNA damage of a total of 200 comets per point was assessed with Comet Assay IV software. The results demonstrated that both halothane and IR caused elevated DNA damage levels, and when applied in combined treatment caused synergistic effect additional damaging effect that was not repaired even 24 hours after exposure. These data confirm concerns about the safety of combined VA and IR exposure, and indicate the need for further investigation on the safety and proper use of the type of anesthetic needed during radiotherapy.


The Indonesian Language: Its History and Role in Modern Society. James Sneddon. Sydney: University of New South Wales Press. 2003. Pp. viii+240. ISBN 0-86840-598-1 (pbk): AUS 49.95.


STEIN MS. Ch. 00269 is a report by haḍa ("), who call themselves ñaśa bīsa (" humble servants"), on behalf of seven rispura (" princes "). It consists of 120 lines, but of that a considerable part cannot yet be translated. The report is concerned with the cities of Ṣacū and Kaṃmicū. Danger from robbers is reported and an investment of the city of Kaṃmicū, so that food and cattle are lacking.


In this paper, we used the notion of operator A+ for defining a new class of set which will be called semi-+-open set, besides we de fine the concepts of generalized semi-+-closed sets and regular generalized semi-+-closed sets. Moreover, some of their properties are shown.


When we experience trials, our faith grows stronger, and our children see the realities of this hard life and the depth of security that a relationship with Christ can bring." Posting about knowing we are children of God from In All Things an online journal for critical reflection on faith, culture, art, and every ordinary-yet-graced square inch of God's creation. https://inallthings.org/you-are-his/


Amino acid (AA) metabolism is altered in type 2 diabetes (T2D), and fasting levels of α‐hydroxybutyrate (α‐HB), a biomarker for insulin resistance, have been suggested to track AA metabolism. We investigated the changes in AA and α‐HB induced by a mixed‐meal tolerance test (MTT) and the effects of sitagliptin treatment.


During the last three years the number of coastal Pitted Ware sites in southern Norrland has increased immensely. The northern border of this cultural expression has been pushed to the northernmost part of Hälsingland, that is as far as our new surveys have reached. In 1993 the site of Fräkenrönningen was excavated. Due to the fact that the cultural layer on this site was excavated in it s totality not just sampled — an analysis concerning the relation between artefacts and constructions on the site have been possible. These new sourcematerials has enabled us to pose questions about settlement structure and settlement patterns that would have been impossible to pursue without these large and consistent materials.


The invention provides a moving coil magnetic-levitation double-workpiece-stage vector circular-arc exchange method and device based on interferometer measurement and belongs to a semiconductor manufacturing equipment technology. The device comprises a supporting frame, a balance mass block, magnetic-levitation workpiece stages, workpiece stage measurement devices, workpiece stage driving devices and workpiece stage charging devices, wherein the two workpiece stages work between a measurement position and an exposure position, the positions of the workpiece stages are measured by adopting a laser interferometer, motion compensation is conducted on the balance mass block by adopting an active compensation structure consisting of dual-motor crank and rocker mechanisms, the workpiece stages are driven by magnetic-levitation planar motors, and the planar motors are adopted to drive the two workpiece stages to achieve quick single-beat arc stage exchange in the double-workpiece-stage exchange process. The problems of large beat number, long trajectories, multiple start-stop links, long stabilization time and the like of an existing stage exchange scheme are solved, stage exchange links are decreased, the stage exchange time is shortened, and the productive rate of a photo-etching machine is improved.


Tech freshmen will receive one of their greatest thrills of college life to morrow afternoon at Grant Field when tney will witness the Golden Tornado swing into action in the first football game of the season against the Clem son Tigers. The cheer leaders will be on hand to lead the largest freshman class since 1929 in the Alma Mater and the school yells, while the Tech band, which is one of the best in years, will play Ramblin' Wreck. It should be considered a great op portunity to be able to see these sea soned grid stars on the field. Tech has some of the best material since her World Championship team. The backfield will be amply filled with Bill Mc Kay, triple threat sophomore, start ing at fullback, Shorty Roberts at quarterback, and Billy Street and (Continued on Page 5) Orientation Period To Be Extended


Electronic devices for the control of culture environmental temperature and for a more flexible operation of the cine camera are described with circuit diagrams. The advantage(s) and limitations of each device are discussed.


This paper describes several case histories of geogrid-reinforced, Mechanically Stabilized Earth (MSE) structures, including walls and slopes, that were designed and constructed for three of the major transportation projects carried out in the Vancouver Region in the last eight years: The Port Mann Highway 1 project, South Fraser Perimeter Road and Low Level Road. The reinforced soil structures were built for grade separation purposes at multiple locations encompassing the various geotechnical environments present in the region varying from highly competent glacial soils to soft, compressible and/or liquefiable soils. The design of the earth structures had to meet performance criteria under seismic conditions and in some cases under exceptionally high loads resulting from the interaction with bridges. The retention systems included varied configurations such as vegetated reinforced soil slopes at diverse inclinations which in many cases blended with the surrounding landscape, vertical or nearly vertical MSE walls and two-stage walls that allowed the construction of bridge abutments on compressible soils. Post-construction performance of the reinforced soil structures has been satisfactory under the working conditions and has met the goals established by the project owners.


Although European sectoral social dialogue is rooted in the creation of the European Union, over the last decade it has undergone changes to its institutional foundations, structures and scope. These can be attributed to a number of developments, including the inclusion of social dialogue in general in the Maastricht Social Agreement and later in Articles 138 and 139 of the EC Treaty, the transformation of older joint committees into 'sectoral social dialogue committees' and the creation of new committees. A significant outcome of the sectoral social dialogue committees, established in 1998, is the increasing production and adoption of joint texts (cf. figure below). Although different trends are apparent between the sectors, in general it appears that there are increasing synergies between the cross-industry and the sectoral social dialogue.


A 38-year-old man presented with inflammatory low-back pain starting at the age of 18 years. It was associated with morning stiffness that eases with works and worsens in the night, along with difficulty in changing posture in bed. After 12 years of onset of disease, the entire spine started becoming increasingly stiff with gradual loss of lumbar lordosis and development of thoracic kyphosis. At the same time he also reported pain and swelling in bilateral knee joint, limiting his day-to-day activity and later developed stiffness of joint and disability. For the …


Postoperative sore throat is a common complication of tracheal intubation, especially double-lumen tube intubation, after general anesthesia. Several studies have been conducted to compare the incidence of postoperative sore throat among patients un-dergoing videolaryngoscope-guided double-lumen intubation with that among patients undergoing Macintosh laryngoscope-guided double-lumen intubation. We purported to summarize all the existing evidences to explore the effect of videolaryngoscope and Macintosh laryngoscope on postoperative sore throat in patients with double-lumen intubation. PubMed, Cochrane Library, EMBASE and China National Knowledge Infrastructure databases were searched for all randomized controlled trials published before 01 June 2021 that compared videolaryngoscopy with Macintosh laryngoscopy for prevention of postoperative sore throat among patients undergoing double-lumen intubation. The results showed that, 9 studies involving 695 patients were included in our meta-analysis. There was no significant difference about the incidence of postoperative hoarseness (risk ratio: 0.80; 95% confidence interval: 0.49–1.32; p-value = 0.38; I2 = 83%), tube malposition (risk ratio: 0.75; 95% confidence interval: 0.07–7.60; p-value = 0.80; I2 = 71%) and the success rate at the first attempt (risk ratio: 1.03; 95% confidence interval: 0.96–1.10; p-value = 0.42; I2 = 70%) between the two groups. We found that the videolaryngoscopy provided much lower incidence of oral injury (risk ratio: 0.49; 95% confidence interval: 0.27–0.89; p-value = 0.02; I2 = 7%) compared with Macintosh laryngoscopy. There was no significant difference in the incidence of postoperative sore throat (risk ratio: 0.74; 95% confidence interval: 0.42–1.32; p-value = 0.31; I2 = 87%) between the two groups. The sensitivity analysis excluding one study suggested that the incidence of postoperative sore throat was lower in the videolaryngoscopy group (risk ratio: 0.64; 95% confidence interval: 0.46–0.89; p-value = 0.008; I2 = 19%). The subgroup analysis suggested that the incidence of postoperative sore throat was lower in the videolaryngoscopy group in studies performed by experienced anesthetists (risk ratio: 0.62; 95% confidence interval: 0.45–0.87; p-value = 0.005; I2 = 5%). The current evidence demonstrates that, experienced anesthetist under the guidance of videolaryngoscope can significantly reduce the risk of postoperative sore throat in patients with double-lumen intubation. Using the videolaryngoscope resulted in a lower incidence of oral injury-related complications. However, there was no advantage in using a videolaryngoscope over Macintosh laryngoscope in the reduction of postoperative hoarseness, tube malposition and the success rate at first attempt.


In this article we discuss the relationship between Information Science and the fields of Library Science, Archival Science and Museology, based on two criteria: the issues of institutional legitimacy and the theoretical and scientific relations. We points to the interdisciplinary character of Information Science and the scientific concept of information as components of enhancing the integration of these three fields.


This paper expounds the individualized,marketization and diversified service modes of information service of public library in the era of knowledge economy,and points out the future development direction of information service of public library.


− Thermophoresis is a transport phenomenon of particles driven by a temperature gradient of a medium. In this paper, we discuss the thermophoresis of particles in microfluidic channels. In a non-fluidic, stagnant channel, the thermophoretic transport of micro-particles was found to be larger in proportion to the voltage applied to the platinum wire heat source installed in the channel. The variation of the temperature around the platinum wire depending on the voltage was estimated, by using the Callendar-van Dusen equation. The thermophoretic behavior of nano-particles in the same system was observed, which is similar to that of the microparticles. Finally, we fabricated a Y-shaped microfluidic channel with a platinum wire heat source installed in the channel, to realize the thermophoretic phenomenon of the particles in the suspension flowing through the channel. It is shown that the flow of the suspension can be controlled based on the thermophoretic principle.


The present invention provides a pressure-sensitive member which is disposed on the support member for supporting the bed occupant and a sensing member comprising a plurality of pressure sensors, to provide a bed occupant monitoring system. Each pressure sensor is configured to supply the reflected wave energy pressure signals by reflecting the intensity incident wave energy in response to pressure applied to the sensor. Each pressure sensor is arranged a pair of optical fibers, each pair of optical fibers and an an input fiber output fiber. Optical fiber, applied light wave energy source for supplying energy, and are connected to the interface electronic apparatus having a wave energy detector for converting the diffused light energy into an electrical signal, the optical fibers input fiber wave energy source in pairs, the output fibers in wave energy detector, are connected.


The lack of attention to the role of emotions generally has led modern learning theories to neglect the importance of emulation as a pedagogical support to students' learning. One reason could be that the influence of teacher personality is not considered in relation to learning outcome. Another reason may be that the concept of emulation has been used as a psychological conception for one-way transmission. From a pedagogical rhetorical perspective, it is here argued that emulation and its pedagogical function is rooted in three human conditions: the biological, moral and political. The framework for this reasoning is discussed, as well as historical changes in pedagogical focus. Finally, it is concluded that the educative character of the teacher has a crucial impact on how willing students are to interact and share the teachers' knowledge, skills and values. Therefore, there is a need for a greater awareness of these aspects to be developed among teachers. (Less)


A tablet consisting of two layers of swelling and rupturable coatings was prepared and evaluated as pulsatile drug delivery system. Aceclofenac was used as model drug. The tablets were prepared by direct compression method. Different ratio of spray-dried lactose and microcrystalline cellulose were then coated sequentially with an inner swelling layer containing a superdisintegrant (croscarmellosesodium) and an outer rupturable layer of ethyl cellulose. The effect of spray-dried lactose and microcrystalline cellulose on swelling layer and rupturable coating was investigated. In vitro dissolution was preformed using the USP paddle (type II) apparatus at speed of 50 rpm by using phosphate buffer pH 7.4 as a dissolution medium. The lag time of the pulsatile tablets of Aceclofenac decreased with increasing concentration of microcrystalline cellulose in the cores and increased with increasing levels of both swelling layer and ruputable ethyl cellulose coating. Increasing levels of water uptake by the ethyl cellulose coating causes bulging and become like gel and forms insoluble skeleton where the drug seems to be timecontrolled release, and thus prolonged the lag time.


The study is conducted with the aim to investigate the effects of job burnout on employees' intentions to stay with the current organization. Mediating role of affective commitment between the relationship of all dimensions of job burnout and intention to stay in the organization is also explored in this study. The research was conducted in banking sector of Pakistan and data was collected from banking sector employees working in different local private, local nationalized and foreign banks located in Lahore city. The study found emotional exhaustion to have significant effects on employees' intent to stay in the organization directly and through the mediation of affective commitment. Whereas lack of accomplishment have only indirect effects on intention to stay through the mediation of affective commitment. Findings of the study provide strong implications for banking management to have careful insight about the attitudinal and behavioral problems of the employees. The limitations and future area of research are also discussed in the study.


GRB 210121A was observed by Insight-HXMT, by the Gravitational wave high-energy Electromagnetic Counterpart All-sky Monitor (GECAM), and by the Fermi Gamma-ray Burst Monitor (Fermi/GBM) on 2021 January 21. In this work, photospheric emission from a structured jet is preferred to interpret the prompt emission phase of GRB 210121A, and emissions from different regimes are observed on-axis. Particularly, the emission from the intermediate photosphere is first observed in the first 1.3 s of the prompt emission, while emissions from the other part are dominant by the emissions from the saturated regime. This offers an alternative explanation compared with previous work. Moreover, the emissions that consider the intermediate photosphere can well interpret the changes in the low-energy photon index α during the pulses. In addition, the evolution of the outflow is extracted from a time-resolved analysis, and a correlation of Γ0∝L00.25±0.5 is obtained, which implies that the jet may be mainly launched by neutrino annihilation in a hyper-accretion disk.


Evolution of Wireless Body Area Network (WBAN) in telemedicine field keep increased along with needs and enhancement of services, nevertheless an efficient and effective form of communication becomes essential for any type of wireless communication network. One of the most important parameter for designing communication network is path loss exponent. Based on that, the purpose of this research is to know the propagation characteristics for on-body and off-body communication by comparing the simulation and measurement using magnetic textile antenna at 2.45 GHz and 924 MHz with distance variation in LOS and NLOS conditions. In this research, friis formula is used to get the path loss exponent value that shows the characteristics of propagation. The calculation of path loss exponent value for simulation and measurement for on-body communication with LOS and NLOS conditions are between 1.7-1.9 while off-body with LOS and NLOS conditions are between 2.1-5.2. These results show that the body affects path loss exponents value and have own characteristics.


Respiratory sound analysis using stethoscope continues to be the mostly used method for the diagnosis of respiratory diseases. This technique depends on detection of symptomatic adventitious sounds present with normal vesicular sounds. However, some factors such as dependence on the practitioner doctor's experience, frequency distortion of the stethoscope and frequency response of the human ear limits the usefulness of this technique [1]. Some computerized systems have been developed to overcome these limitations. In this study, use of Empirical Mode Decomposition (EMD) have been explored for the detection of discontinuous (i.e. crackles) and continuous (i.e. wheezes) adventitious sounds that are present in the lung sounds when the patient has a respiratory disease. EMD is an adaptive technique for nonstationary signals and nonlinear signals [2]. It decomposes signals into oscillatory intrinsic modes called Intrinsic Mode Functions (IMFs) using a data driven algorithm. It is shown on the real lung sounds that these IMFs are helpful for easy detection of both the crackles and the wheezes.


Neutrophil extracellular traps (NETs) form when stimulated neutrophils undergo an oxidative burst and emit a complex of DNA, histones, pro-inflammatory and antibacterial proteins in a process distinct to other forms of neutrophil disposal such as apoptosis or necrosis. NETs have been associated with a number of important disease processes ranging from infectious diseases to sterile inflammatory conditions. This multi-potent role in immunity has led to conflicting opinion and evidence as to the beneficial or detrimental effects of NETs in immunity and indeed whether they have a major role in humans is as an antimicrobial defence [1]. In this issue of the European Respiratory Journal, Ebrahimi et al. [2] demonstrate an association between high levels of nucleosomes (a marker of NETs) and adverse outcome in community-acquired pneumonia (CAP), in terms of time to patient stability, length of intravenous antibiotic treatment and time to discharge. Additionally, and perhaps more importantly, those with the highest levels of NETs had a higher (all cause) mortality. Interestingly, when the effects of corticosteroids on CAP outcome were investigated in this cohort, although these patients had a better clinical outcome they had higher persisting levels of NETs at days 5 and 7 (a feature also seen in the placebo arm of the trial where slower to decline levels of NETs were associated with better outcome), albeit they had started at a lower baseline. This presents a dichotomy where high levels of NETs (at presentation and over the course of CAP) are associated with bad outcome and death, whereas persisting lower levels of NETs into recovery are associated with better outcome. We might speculate that excessive levels of NETs in CAP could represent patients with a higher level of neutrophil activation in response to more severe infections or indeed patients with a higher level of systemic inflammation (a feature previously shown to be associated with adverse outcome in CAP [3]), but the clinical and pathological significance of slower to resolve NETs are less clear. Nevertheless, the present study suggests that the measurement of NETs may be a powerful biomarker of outcome in CAP. The authors go further in suggesting that excessive NETs at baseline and an early exhaustion of NET formation in the context of severe CAP is a potential mechanism leading to poor patient outcome; however, this remains speculative and further mechanistic studies will be required to investigate this feature. So, is there an optimal level of NETs at which health is maintained and too many or too few are detrimental? NETs have been suggested to have both detrimental and beneficial roles in lung infection and inflammation. The reality probably lies somewhere in the middle, where adequate NETs are needed to help control infection but excessive NETs cause damage http://ow.ly/IKH130jqFP3


Laser Induced Incandescence (LII) is an increasingly applied diagnostic technique for soot volume fraction and particle diameter measurements in flames and combustion systems. LII exhibits excellent sensitivity [1] and offers the possibility of two-dimensional imaging of soot volume fraction and particle size measurements [2-4]. For particle sizing it is necessary to determine the temporal decay of the LII signal and to apply a numerical code developed on the basis of a rather complex theory involving many physical and chemical phenomena [5]. The intensity of LII signals peak, taken within a certain range of laser fluences, has been experimentally shown to be proportional to soot volume fraction. Actual soot concentration measurements are in general performed after a calibration procedure of LII signals in a flame of known soot concentration. Recently two research groups proposed a two-color version of the LII technique for absolute soot measurements without the necessity of a previous calibration in a flame [6-7]. This technique is just an extension of the well known two-color emission technique [8]. The key point is the fact that, within a certain laser fluence range, the maximum temperature is independent on the particle size and is always close to the soot vaporization temperature. If one is able to reach this temperature without inducing substantial mass losses during the laser pulse, accurate spatially-resolved soot concentration measurements are feasible. In this work we have employed this technique, trying to explore its features and critical aspects. To this purpose the laser beam was accurately controlled both in shape and fluence, being the structure of the probe volume a key point. The detection system efficiency (collection optics, monochromator and photomultiplier) was accurately determined with a calibrated lamp. Soot maximum temperature versus laser fluence was determined in order to find the best experimental conditions. Measurements were taken in a laminar diffusion flame of ethylene. The LII results were compared with classical extinction measurements. Excellent agreement demonstrated the capability of the technique.


PURPOSE: A vertical wall afforestation apparatus is provided to firmly fix a ground frame for planting plants, and to regularly supply nutrients and water to the plants planted on the ground frame. CONSTITUTION: A vertical wall afforestation apparatus plants trees and plants on a vertical wall(12) of a building(10). The vertical wall afforestation apparatus comprises the following: a horizontal pipe(20) including a multi valve(24) on a location facing ground frames(40); first and second fixing rails(30,32) fixed to the vertical wall; the ground frames with both ends inserted into the fixing rails, formed in a hexahedron form with an opened front side; and an artificial ground installed in the inside of a unit box.


Magnetic fluxes for maximum efficiency are calculated at five operating points as speed and torque are varied. The surface of magnetic flux for maximum efficiency is calculated by using the five points, Then, maximum efficiency control is fulfilled with the magnetic flux calculated from the surface of magnetic flux at a given speed and torque. Simulation results verify the effectiveness of the proposed method.


It is well established that a subgroup of depressed patients have an associated hypersecretion of cortisol and loss of normal circadian secretion pattern. Moreover, a negative response to the dexamethasone suppression test has been established as a good state-related marker for depression in nonsuppressors, and this nonsuppressive state usually normalizes with the resolution of the depressive symptoms.' The cause of this abnormal glucocorticoid secretion pattern is not clear. Previous studies have demonstrated a higher concentration of corticotropin-releasing factor (CRF) in the cerebrospinal fluid of depressed patients, and results of the CRF stimulation test point to the possibility of a limbic-hypothalamic overdrive. Some studies reported a decrease of the cytoplasmic concentration of glucocorticoid receptors in lymphocytes of depressed patients while others reported a normal concentration but a decreased function of the glucocorticoid receptor. Whether an increased CRF-ergic drive or the recently demonstrated deficient glucocorticoid fast feedback or both concur to produce the abnormal glucocorticoid secretion in this group of depressed patients is not known. A transgenic (TG) mouse model of impaired glucocorticoid type I1 receptor function which is normalized by antidepressant treatment was previously developed.2 We now report preliminary results on the behavioral characterization of these animals, as part of a more global endeavor


This article provides a case study of how natural resource inventory information from preexisting geographic information system (GIS) data layers and an analysis of IKONOS satellite imagery can be combined with data from a survey of landowners to create a unique strategic planning process for watershed protection. The ability to identify important environmental features such as unfragmented forest, stream systems, and forested wetlands is an important part of watershed conservation projects, as is the ability to identify landowners cost/benefit perceptions and intentions concerning conservation practices such as forest stewardship. Together these two functions permit land protection techniques and landowner outreach strategies to be targeted where they will be most efficient and effective. Knowing the disposition of landowners in priority areas allows decision makers to plan their communication with these landowners strategically.


As I write this editorial in August 2021 from my home in Melbourne, Australia, during a global pandemic with ongoing lockdowns in our country, the role of the Nordic Journal of Music Therapy seems more crucial to our profession than ever before. Opportunities to virtually connect across the globe through multiple forums, whether on a written page or through cloud-based video conferencing and social media have provided some sense of connection. The social distancing requirements of the pandemic have also greatly accelerated the ways that technology is used by music therapists across education, practice, professional development, and research. These virtual opportunities are exciting and have provided us with alternative avenues to continue our work. I look forward to reading about these advances in the forthcoming Nordic Journal of Music Therapy Special Issue, edited by Wendy Magee and Tony Meadows. Nonetheless, I am concerned that music therapy in virtual spaces, sometimes a necessity but other times a convenience, may lack the nuances of human connection described with in-person shared musicking experiences in the here and now (Stige & Aarø, 2012). How does music therapy over a virtual space foster authentic human connection and safe practices in research and clinical work? Group singing and live music, arguably fundamental to music therapy practice, is severely compromised over virtual modes, not only because of the technical challenges of lag and sound but also because there is no opportunity for physical connection. Inperson choir participation facilitates connection through experiences of attunement and vocal creation with others, which creates a sense of transcendence that is "beyond [the] ability to explain or describe with words" (Moss, 2019, p. 215). Similarly, live preferred songs in therapy by people recovering from traumatic medical events provide "human connection that does not exist in recorded music" (Selle & Silverman, 2020, p. 67). These opportunities to be physically present with others through music when faced with challenging life situations install a sense of hope that alternative optimistic experiences may be possible (Moss, 2019; Selle & Silverman, 2020). There is no doubt that online music therapy affords many advantages, including convenience and accessibility. As a Bonny Method of Guided Imagery and Music (BMGIM) trainee, I have embraced opportunities to facilitate sessions with, and receive sessions and supervision from people across the world. Based on conversations with colleagues and personal experience, online BMGIM is absolutely possible once the various computer settings have been mastered (withstanding continual updates) (Sanfi, 2019). However, the challenge of holding a safe therapeutic space through a computer screen while working within this complex and deeply psychodynamic approach is challenging. How do you carefully guide and hold a client within a 2-dimensional space? How does one observe and respond to the subtle changes in breathing, small NORDIC JOURNAL OF MUSIC THERAPY 2021, VOL. 30, NO. 5, 401–403 https://doi.org/10.1080/08098131.2021.1970405


EDITORIAL ADVISORY BOARD Massimo Attanasio, University of Palermo, Italy Ayanendranath Basu, Indian Statistical Institute, India Adrian Bowman, University of Glasgow, UK Clive Bowman, University of Reading, UK Trevor Cox, Unilever, UK Neville Davies, RSS Centre for Statistical Education, Nottingham, UK Petros Dellaportas, Athens University of Economics and Business, Greece Peter J Diggle, University of Lancaster, UK Tim Dunne, University of Cape Town, South Africa Wally Gilks, University of Leeds, UK Peter Green, University of Bristol, UK and University of Technology, Sydney, Australia David Hand, Imperial College London, UK Masahito Kobayashi, Yokohama National University, Japan Young Jo Lee, Seoul National University, Korea Victor Leiva, University of Valparaiso, Chile W. K. Li, University of Hong Kong, Hong Kong Francisco Louzada, University of São Paulo at São Carlos, Brazil Douglas Montgomery, Arizona State University, USA Ernst Wit, University of Groningen, the Netherlands Regression model for interval-valued variables based on copulas Eufrásio de A. Lima Neto and Ulisses U. dos Anjos 2010 The effects of data input errors on subsequent statistical inference Marcin Kozak, Wojtek Krzanowski, Izabela Cichocka and James Hartley 2030 Emulation and interpretation of high-dimensional climate model outputs Philip B. Holden, Neil R. Edwards, Paul H. Garthwaite and Richard D. Wilkinson 2038 Robust estimation for non-homogeneous data and the selection of the optimal tuning parameter: the density power divergence approach Abhik Ghosh and Ayanendranath Basu 2056


The invention relates to the construction, in particular, to strengthen the structures of reinforced concrete hollow-core slabs, providing overlapping discharge due to increased operating loads. The design includes amplification gain elements, each of which is rigidly connected with two floor slabs, arranged on opposite sides of the wall or a beam on which they rest. Rigid connection effected by anchors one end of which is hardwired into the voids slabs and fixed to the second gain elements so that the longitudinal axis of each of the anchor is spaced from a wall or a beam, which supports the plate in the region amplified Where Δl - distance from a wall or a beam, on which is based the amplified floor slab, to the longitudinal axis of the anchor, m; l - distance between two walls or beams, which support the floor slab amplified, m; q - the original design service load, perceived amplified slab floors, kg / m; Dq - Additional rated operating load, perceived amplified slab floors, kg / m; l f-ly 1 Fig.


In the following note I address the figure of the British theologian and mathematician Baden Powell (1796-1860), by drawing on an important monograph by Prof. Pietro Corsi recently published in Italian. Powell's work responded to a cultural strategy of assimilation of philosophical and scientific novelties within a fundamentally conservative view of society. Here, I provide a brief sketch of Powell's attempt to rethink natural theology in the light of the latest scientific hypotheses, including those regarding the evolution of living beings


Double bond migration of 2,5-dienones 3 to 2,4-dienones 2 (e.g. pseudoionone) was effectively carried out by using nickel acetylacetonate catalyst in N-methyl-2-pyrrolidone solvent.


With the rise of Dockless Shared Bicycles in cities, the rational division of docks for Shared bikes has become an important issue in urban road planning. In the initial stage of Dockless Shared Bicycles, randomly parked bicycles bring great pressure to urban road traffic because there is no fixed parking area. The appearance of an electronic fence has improved the user's shared bicycles specification to a certain extent. However, due to the variability of urban road planning, it is very necessary to optimize the parking area of bicycles regularly. In this paper, the cycling data of Shared bicycles are studied by using the Spatio-temporal clustering algorithm, the flow and parking rules of dockless Shared bicycles are explored to seek the optimal division of bicycles areas.


Mitochondrial trifunctional protein (TFP) deficiency is a rare disorder of the fatty acid β‐oxidation cycle with heterogeneous phenotypes and occurs secondary to either α‐ or β‐subunit mutations. We characterized the neuromyopathic phenotype of TFP deficiency through adolescence or adulthood in 11 patients, 8 with β‐subunit mutations and 3 with α‐subunit mutations. Two independent clinical features occurred: infantile‐onset progressive peripheral neuropathy and episodic exercise‐, illness‐ or fasting‐induced rhabdomyolysis accompanied by respiratory failure (in five patients). The combination of episodic rhabdomyolysis and peripheral neuropathy occurred in 10 of the 11 patients. The neuromyopathic phenotype is common in TFP deficiency (11 of 27 families from our cohort). Therefore, this disorder must be considered in the differential diagnosis of progressive peripheral neuropathy with or without episodic myoglobinuria. Muscle Nerve 29: 66–72, 2004


The stylus arm restraint comprises an element disposed substantially perpendicular to the stylus arm, and having a portion that is received in a recess provided in the cartridge housing when the stylus arm is held inside the cartridge. The reception of the stylus arm-mounted element in the cartridge recess limits motion of the stylus arm during transit.


Glioblastomas represent the most common primary brain tumors, and carry an extremely poor prognosis (survival <1 year). While microarray analyses have identified 4 subgroups of glioblastomas, clearly additional biomarkers are essential for the diagnosis and treatment of these deadly tumors. G protein coupled receptors (GPCRs) represent the most abundant receptor family encoded by the human genome, and are involved in multiple cellular processes, including growth, structure, and migration, making GPCRs attractive targets for the treatment of cancers. Orphan GPCRs are often excluded from microarray analysis, and thus their role in glioblastomas may have been overlooked. We therefore sought to evaluate the expression of orphan GPCRs in glioblastomas using a novel, multiplex PCR‐based orphan GPCR MasterMix technology that we developed to rapidly elucidate the orphan GPCR expression profile of any human tissue or cell type. Using this technology, we have found that tumors tend to exhibit a unique "fingerprint" in terms of their orphan GPCR expression. This technology may be useful for identifying orphan GPCRs that could be used as diagnostic markers or therapeutic targets for these devastating neoplasms.


The legal problem in the practice of land registration in Indonesia is the vulnerability of claims in the Court for those who already have land certificates. This means that the purpose of land registration that wants to provide legal certainty of cadastral land rights has not yet been achieved. This is a legal consequence of the use of a negative publicity system with a positive element in land registration. The purpose of this study is to determine the philosophical and sociological foundation of the choice of a negative publicity system with a positive element in land registration in Indonesia. Socio legal research approach method is used. The results showed that the philosophically the choice is for justice and welfare of the people and the state is responsible for its welfare. The choice is supported by the condition of land ownership during the legislation of national land regulations in 1960s in which the people were mostly subject to customary law. The choice was to provide legal protection to the actual rights holders and obtained in good faith.


THIS SPECIAL ISSUE IS THE FIRST SUSTAINED ACADEMIC EXPLORATION of the contemporary adventure narrative across a wide range of media. While many other types of texts that emerged during the late-eighteenth and nineteenth centuries, including gothic horror, romance, travel narrative, and melodrama, have received considerable attention, the contemporary adventure narrative has been left out of or taken for granted by recent popular culture studies. The absence of adventure in recent scholarship may, paradoxically, have to do with the ubiquitous presence of the form. Like many other genres, adventure has invaded and merged with a host of other modes and genres, from television reality game shows, such as Survivor, to gritty war films, such as Black Hawk Down. Indeed, as several of the contributions to this issue demonstrate, the contemporary adventure form often appears in trans-genre texts where the adventure component is perceived as secondary. While contemporary adventure is severely under-researched, the nineteenthto early-twentieth-century British and US variant has been closely scrutinized. This scholarship has primarily explored two different concerns: one related to supposedly universal mythical narratives and the other closely tied to the long history of European colonialism. Regarding the former concern, Joseph Campbell's not only influential but also much criticized work in the middle of the twentieth century maps a wide range of global mythologies. Campbell worked, like C. G. Jung or James Frazer, from a disciplinary framework that was partly psychological and partly anthropological, and he


The accident and summon for the road user increasing from days to days. There are many
technology implement to the vehicle to reduce the damage if an accident occur. However,
it still cannot reduce number of accident because of the careless and fast driving is the will
leads for an accident to happen. The purpose of this project is to develop a product that can
measure the motorcycle's speed and displays the speed value on the helmet's visor.
Basically, infra-red sensor is use as a sensor for speed measurement device. This sensor
will be attach near to the wheel and as sensor detects object will send the pulse to process
device. The process device is the Programmable Integrated Circuit 16F877 A act like
Central Processing Unit (CPU) that controls the system for the product. The data from
infra-red sensor will be process by the C programming and produce the speed reading.
LCD were used to displays the speed reading on the helmet's visor. The alarm trigger once
the speed calculated is exceeding at certain limit.


Number EC Grant Number Grant Title WHO Award Number Description of Goods or Services Supplier Name Supplier Country Supplier Location Date of Contract Approval Contract Amount approved against EC Grant in USD 202931449 NDICI-GEO-NEAR/2021/425-845 COVID-19 VACCINE PREPAREDNESS AND DEPLOYMENT IN THE EUROPEAN UNION'S EASTERN PARTNER COUNTRIES. 71475 E3000000 INTERTRADE INTERNATIONAL SERVICES SA Switzerland NON-CAT 9/30/2022 4,664,079 $ 202987466 ECHO/DRF/BUD/2021/91040 Support to the rollout of COVID-19 national vaccination campaigns in Africa and reinforcement of national health systems' resilience to epidemics 72723 Implementation of programmes GOVERNMENT OF CAMEROON Cameroon NON-CAT 10/26/2022 4,640,079 $ 202817563 TF-MADAD/2017/T04.74 TF-MADAD/2017/T04.74 PROVISION OF CHRONIC MEDICATIONS OF PRIMARY HEALTH CARE CENTERS FOR VULNERABLE SYRIAN REFUGEE AND LEBANESE HOST COMMUNITIES. 67506 Implementation of programmes YOUNG MEN'S CHRISTIAN ASSOCIATION (YMCA) Lebanon NON-CAT 2/23/2022 4,236,151 $ 202894376 TF-MADAD/2020/T04.202 EUTF JORDAN HEALTH PROGRAMME FOR SYRIAN 70107 D1300000 KHOURY DRUG STORE CO.LTD Jordan NON-CAT 6/24/2022 3,918,237 $ 203032384 FED/2020/420-537 Health Support in Response to COVID-19 in the Pacific 71295 Shipping PF LINE PROXY SUPPLIER Switzerland NON-CAT 12/16/2022 2,821,535 $ 202892264 TF-MADAD/2017/T04.74 TF-MADAD/2017/T04.74 PROVISION OF CHRONIC MEDICATIONS OF PRIMARY HEALTH CARE CENTERS FOR VULNERABLE SYRIAN REFUGEE AND LEBANESE HOST COMMUNITIES. 67506 Implementation of programmes CONNECTING RESEARCH TO DEVELOPMENT (CRD) Lebanon NON-CAT 6/21/2022 2,082,988 $ 202950394 ECHO/SYR/BUD/2022/91011 Sustaining Provision of Life Saving Health Services Within Humanitarian Response in Syria Through the Provision of Integrated Primary and Specialized Secondary Health Services to the Most Vulnerable Groups, Syrian Arab Republic 73812 D0600000 PHARMEDICA ECZA DEPOSU TICARET LIMITED SIRKETI Türkiye NON-CAT 9/20/2022 1,810,709 $ 203027985 ECHO/-AS/BUD/2021/91023 PROVIDING EMERGENCY, TRAUMA AND PRIMARY HEALTH CARE SERVICES INCL THE TREATMENT OF SEVERE ACUTE MALNUTRITION WITH COMPLICATIONS,RESPONSE TO GENDER BASED VIOLENCE AND COMMUNICABLE DISEASE OUTBREAKS TO POPULATIONS IN UNDERSERVED AREAS OF AFGH 72147 Implementation of programmes ORGANIZATION FOR COMMUNITY COORDINATION EVELOPMENT Afghanistan ON-CAT 12/8/2022 1,330,291 $ 202897573 ECHO/UKR/BUD/2021/91005 Live-saving emergency assistance in the health sector in non-government controlled areas of Ukraine 72155 Implementation of programmes GLOBAL RESPONSE MANAGEMENT United States of America NON-CAT 6/28/2022 1,300,081 $ 202998723 IMDA ECHO/SYR/BUD/2021/91063 Strengthening national COVID-19 response with focus on early and safe diagnosis of cases, strengthening surveillance, and support to continuity of chronic disease care for the vulnerable populations in the context of the crisis in Lebanon 72609 Implementation f programmes YOUNG MEN'S CHRISTIAN ASSOCIATION (YMCA) Lebanon NON-CAT 11/7/2022 1,235,567 $ 203031619 ECHO/-AS/BUD/2021/91023 PROVIDING EMERGENCY, TRAUMA AND PRIMARY HEALTH CARE SERVICES INCL THE TREATMENT OF SEVERE ACUTE MALNUTRITION WITH COMPLICATIONS,RESPONSE TO GENDER BASED VIOLENCE AND COMMUNICABLE DISEASE OUTBREAKS TO POPULATIONS IN UNDERSERVED AREAS OF AFGH 72147 Shipping PF LIN PROXY SUPPLIER Switzerland ON-CAT 12/27/2022 1,051,352 $ 202890955 TF-MADAD/2020/T04.202 EUTF JORDAN HEALTH PROGRAMME FOR SYRIAN 70107 D0600000 GSK VACCINES BELGIUM SA Belgium NON-CAT 6/20/2022 968,000 $ 202814919 ACA/2020/420-356 Mitigating the Health effects of COVID-19 Emergency in Afghanistan 71358 Implementation of programmes AGENCY FOR ASSISTANCE AND DEVELOPMENT OF AFGHANISTAN (AADA) Afghanistan NON-CAT 2/17/2022 936,178 $ 202842754 IMDA ECHO/SYR/BUD/2021/91063 Strengthening national COVID-19 response with focus on early and safe diagnosis of cases, strengthening surveillance, and support to continuity of chronic disease care for the vulnerable populations in the context of the crisis in Lebanon 72609 D0900000 ABBOTT RAPID DX INTERNATIONAL LIMITED Ireland CAT 5/4/2022 900,000 $ 202939543 ECHO/UKR/BUD/2021/91005 Live-saving emergency assistance in the health sector in non-government controlled areas of Ukraine 72155 E3000000 PARAMED INTERNATIONAL FZCO United Arab Emirates NON-CAT 9/19/2022 856,840 $ 202897619 ECHO/-AS/BUD/2021/91023 PROVIDING EMERGENCY, TRAUMA AND PRIMARY HEALTH CARE SERVICES INCL THE TREATMENT OF SEVERE ACUTE MALNUTRITION WITH COMPLICATIONS,RESPONSE TO GENDER BASED VIOLENCE AND COMMUNICABLE DISEASE OUTBREAKS TO POPULATIONS IN UNDERSERVED AREAS OF AFGH 72147 Implementation of programmes ORGANIZATION FOR COMMUNITY COORDINATION EVELOPMENT Afghanistan ON-CAT 11/9/2022 832,770 $ 202878349 ECHO/PSE/BUD/2021/91004 Improved emergency preparedness response and humanitarian advocacy for health for the most vulnerable in oPT, Palestinian Territory Occupied 72240 Infrastructure, security, licences UNOPS Denmark NON-CAT 6/1/2022 804,292 $ 202998312 ECHO/-XA/BUD/2021/91043 EMERGENCY RESPONSE TO COVID-19 PANDEMIC IN SRI LANKA 72361 H0500000 FLEISCHHACKER LLP Singapore NON-CAT 11/16/2022 802,679 $ 202993995 ECHO/UKR/BUD/2021/91005 Live-saving emergency assistance in the health sector in non-government controlled areas of Ukraine 72155 E3000000 AMEX EXPORT-IMPORT GMBH Austria NON-CAT 11/2/2022 797,680 $ 203029493 ECHO/-AS/BUD/2021/91023 PROVIDING EMERGENCY, TRAUMA AND PRIMARY HEALTH CARE SERVICES INCL THE TREATMENT OF SEVERE ACUTE MALNUTRITION WITH COMPLICATIONS,RESPONSE TO GENDER BASED VIOLENCE AND COMMUNICABLE DISEASE OUTBREAKS TO POPULATIONS IN UNDERSERVED AREAS OF AFGH 72147 Implementation of programmes HUMANITARIAN ASSISTANCE AND DEVELOPMENT A SOCIATION FOR AFHGANISTAN (HADAAF) Afghanistan ON-CAT 12/11/2022 772,153 $ 202804612 ACA/2020/417-869 European Union Assistance to Address Top Priority Health-Related Preparedness and Response Efforts of Uzbekistan to Combat COVID-19 Outbreak 70699 L4017000 LEAD EXPERTS ENGINEERING MCHJ Uzbekistan NON-CAT 1/31/2022 741,065 $ 202949693 ECHO/-AS/BUD/2021/91023 PROVIDING EMERGENCY, TRAUMA AND PRIMARY HEALTH CARE SERVICES INCL THE TREATMENT OF SEVERE ACUTE MALNUTRITION WITH COMPLICATIONS,RESPONSE TO GENDER BASED VIOLENCE AND COMMUNICABLE DISEASE OUTBREAKS TO POPULATIONS IN UNDERSERVED AREAS OF AFGH 72147 Implementation of programmes AFGHAN HEALTH AND DEVELOPMENT SERVICES (AHDS) Afghanistan ON-CAT 9/14/2022 737,465 $ 202921842 TF-MADAD/2021/T.04.300 SUPPORTING THE RESPONSE TO THE BEIRUT BLAST AND HEALTH SYSTEM'S STRENGTHENING THROUGH THE PROVISION OF ESSENTIAL MEDICATIONS FOR CHRONIC AND ACUTE DISEASES FOR VULNERABLE SYRIAN REFUGEES AND LEBANESE HOST COMMUNITIES 72682 D0600000 MI RO LABS LIMITED India ON-CAT 8/9/2022 698,760 $ 202938864 ECHO/UKR/BUD/2021/91005 Live-saving emergency assistance in the health sector in non-government controlled areas of Ukraine 72155 E3000000 TOYOTA GIBRALTAR STOCKHOLDINGS LTD. Gibraltar NON-CAT 8/31/2022 690,762 $ 202951608 ENI/2020/421-525 EU4Moldova: Facility to support the health response to the COVID-crisis 71346 D0900000 ABBOTT RAPID DX INTERNATIONAL LIMITED Ireland CAT 10/11/2022 675,000 $ 202798458 ECHO/-AS/BUD/2021/91023 PROVIDING EMERGENCY, TRAUMA AND PRIMARY HEALTH CARE SERVICES INCL THE TREATMENT OF SEVERE ACUTE MALNUTRITION WITH COMPLICATIONS,RESPONSE TO GENDER BASED VIOLENCE AND COMMUNICABLE DISEASE OUTBREAKS TO POPULATIONS IN UNDERSERVED AREAS OF AFGH 72147 Implementation of programmes JUST FOR AFGHAN CAPA ITY AND KNOWLEDGE Afghanistan ON-CAT 5/13/2022 670,283 $ 203026449 MPTF 132190 AFG-22/3481/RA1 Improving access of the vulnerable people to primary and essential healthcare, emergency nutrition, and outbreak response services 74503 Implementation of programmes HEALTHNET TPO Afghanistan NON-CAT 12/7/2022 666,068 $ 202962023 ECHO/UKR/BUD/2021/91005 Live-saving emergency assistance in the health sector in non-government controlled areas of Ukraine 72155 E3000000 ORGANIZATION FOR SECURITY AND CO-OPERATION IN EUROPE Austria NON-CAT 9/29/2022 648,044 $ 202939206 ECHO/-AS/BUD/2021/91023 PROVIDING EMERGENCY, TRAUMA AND PRIMARY HEALTH CARE SERVICES INCL THE TREATMENT OF SEVERE ACUTE MALNUTRITION WITH COMPLICATIONS,RESPONSE TO GENDER BASED VIOLENCE AND COMMUNICABLE DISEASE OUTBREAKS TO POPULATIONS IN UNDERSERVED AREAS OF AFGH 72147 Implementation of programmes AFGHAN YOUTH SERVICE ORGANIZATION (AYSO) Afghanistan ON-CAT 8/30/2022 635,597 $ 202921837 IMDA ECHO/SYR/BUD/2021/91063 Strengthening national COVID-19 response with focus on early and safe diagnosis of cases, strengthening surveillance, and support to continuity of chronic disease care for the vulnerable populations in the context of the crisis in Lebanon 72609 D0600000 MEDOCHEMIE LTD. Cyprus NON-CAT 8/25/2022 633,134 $ 203032233 ECHO/-AS/BUD/2021/91023 PROVIDING EMERGENCY, TRAUMA AND PRIMARY HEALTH CARE SERVICES INCL THE TREATMENT OF SEVERE ACUTE MALNUTRITION WITH COMPLICATIONS,RESPONSE TO GENDER BASED VIOLENCE AND COMMUNICABLE DISEASE OUTBREAKS TO POPULATIONS IN UNDERSERVED AREAS OF AFGH 72147 Shipping PF LINE PROXY SUPPLIER Switzerland ON-CAT 12/27/2022 630,487 $ 202851457 ECHO/UKR/BUD/2021/91005 Live-saving emergency assistance in the health sector in non-government controlled areas of Ukraine 72155 D0601000 IMRES B.V. Netherlands CAT 4/28/2022 626,850 $ 202908108 ECHO/SYR/BUD/2022/91011 Sustaining Provision of Life Saving Health Services Within Humanitarian Response in Syria Through the Provision of Integrated Primary and Specialized Secondary Health Services to the Most Vulnerable Groups, Syrian Arab Republic 73812 Implementation of programmes WORLD VISION INTERNATIONAL Jordan NON-CAT 7/15/2022 622,866 $ 202966353 ECHO/SYR/BUD/2022/91011 Sustaining Provision of Life Saving Health Services Within Humanitarian Response in Syria Through the Provision of Integrated Primary and Specialized Secondary Health Services to the Most Vulnerable Groups, Syrian Arab Republic 73812 Implementation of programmes AL HEKMA HO PITAL Syria


The synthesis of all four possible stereoisomers of enantiopure and diastereomerically pure or highly enriched α-branched [2.2]paracyclophanylalkylamines is described. Key step is the nucleophilic 1,2-addition of alkyllithium reagents to hydrazones of 4-formyl[2.2]paracyclophane derived from the chiral auxiliaries SAMP/RAMP and RAMBO/SAMBO via chromatographic epimer separation. Reductive N-N bond cleavage of the resulting hydrazines, followed by treatment with benzyloxycarbonyl chloride afforded the N-Cbz-protected diastereo- and enantiopure (de, ee ÷ 99%) or diastereomerically enriched (de = 89-96%) title amines.


In the production of molded coke one source of emissions of toxic substances is the excess heat carrier gas (640 m/sup 3/ per ton of charge). In addition to the gaseous components, it contains, g/m/sup 3/: water 360, tar vapor 3-5, coal dust 2-6. The goal of the present article was to evaluate the possibility of purifying this gas by thermal oxidation. The investigations were conducted on a laboratory apparatus with a quartz reactor (length 200 mm, diameter 14 mm), heated by a tube furnace. The tar is injected by a plunger metering pump into a gas mixture, where it is evaporated at 150/sup 0/C in a current of gas; then the tar vapors enter the reactor. The tar for oxidation was obtained in the low-temperature (600/sup 0/C) semicoking of coal; in the experiments a fraction (70 wt.% tar) with a boiling point up to 360/sup 0/C was used. The fraction contained 8% bases, 35% phenols, and 57% neutral part, consisting of paraffins, naphthenes, alkyl-substituted aromatic hydrocarbons and neutral oxygen-containing compounds.


This research was aimed to enhance students' speaking skill at eight grade students of Islamic Junior High School Sawit Seberang, Langkat Regency. The subject of this research was a class consisted of 40 students. The research consisted of two cycles. Each cycles consisted of two meetings. The object of this research was to enhance students' speaking skill by the use of Ice Breaker strategy. This research was conducted by using Classroom Action Research. Qualitative and Quantitative data were used in this research. The qualitative data while the quantitative data were taken from students' score in Pre-Test, Post Test I, and Post-Test II. The result of analyzing data indicated that there was significance enhancement on students' speaking skill after the use of Ice Breaker strategy. It can be seen from the students' score in every cycle. In Pre-Test, there were only 30% (12 students) whose score up to 75. In Post-Test I, there was 52.5% on the percentage of students whose score up 75 (21 students), while in Post-Test II there were 80% students whose score up 75 (32 students). From data analysis, it showed that there was enhancement on students' speaking skill. It can be seen from the mean of Post-Test II was 80.3. In other words, students' speaking skill has enhanced. Based on the qualitative data, the students gave good responses and showed enthusiasm after the use of Ice Breaker strategy in speaking skill.


The facile synthesis of all-cis-tetrasiloxycyclotetrasiloxanes (extended cyclic siloxanes) [i-BuSi(OSiHMe2)O]4 1, [PhSi(OSiHMe2)O]4 2, and [CH2 = CHSi(OSiHMe2)O]4 3 was accomplished via sodium or potassium silanolates from respective trialkoxysilanes. The treatment of 1 or 2 with m-chloroperoxybenzoic acid afforded respective extended cyclic silanols [i-BuSi(OSiMe2OH)O]4 4 and [PhSi(OSiMe2OH)O]4 5. The structures of 4 and 5 were unequivocally established by X-ray crystallography. Among these new compounds, compound 3 possesses both vinyl and hydrosilyl groups in the molecule, thus this could serve as a potential monomer of well-defined cage silsesquioxanes. Extended cyclic silanols 4 and 5 contain four silanol moieties in the same direction, and application of host molecules or building units of cage silsesquioxanes is expected.


On the west coast of Vanua Lava (Banks group, North Vanuatu), farmers do not only cultivate taro on irrigated terraces to live, but live to cultivate and eat taro every day. Taro holds the memory of the ancestors, the village, and the place of its production. This place—the taro water-gardens—is named rot, and is described in this article from an ecological and social point of view. The main goal is to understand why the inhabitants of the west coast of Vanua Lava are producing so much taro. Rot has to be managed with water canals, and includes t qēl which are irrigate pondfi elds with wet and dry alternation structured in terraces (7.10 t dry matter/ha), mat which consists of modifi ed rivers or streams (20.1 t t/ha), and boak which are k drained swamps (10.2 t/ha). The difference between estimates of the taro consumed (95.7 t) and the taro produced each year (146.5 t) leaves us to believe that a lot of taro is harvested in surplus for local subsistence needs, which reinforces the 'social generosity' characteristic of Melanesian societies. The taro water-gardens of Vanua Lava offer a considerable food potential for the population of today and tomorrow. 1. TARO, A PLANT IN TOUCH WITH THE ANCESTORS Irrigated pondfi eld terracing is a system of cultivation that has declined throughout much of Oceania or has even been abandoned. Reasons for this growing indifference have been summarized as 'European contact and establishment of colonial relations, an end to traditional internecine confl ict, population decrease, and the emergence of island society into a global marketplace' (Kuhlken 2002: 186). According to the same author, persistence of such a timeconsuming activity is mainly due to 'cultural forces'. This paper will show how such 'forces' are indeed glorifi ed by people living on the west coast of Vanua Lava (Banks group, North Vanuatu). The inhabitants of Vanua Lava display without a doubt a culture based on taro (Colocasia esculenta L.). Taro is good to eat and to think. They do not merely cultivate taro to live, but one could almost say that they live to cultivate and eat taro every day. This 'taro civilization' to borrow A.-G. Haudricourt's (1964: 93) expression 'yam civilization' for New Caledonia, produces a landscape and a particular system of spatial organization based on the various practices of production and social organization. As an important object of culture, taro establishes a link between two worlds; the surface where people live and the chthonian world where the dead live, whose knowledge, vegetal material and taro water-gardens are inherited


This paper presents a novel 3 D. O. F haptic interface which is designed to meet the interaction requirement of teleoperation tasks and virtual reality applications. The mechanism design takes the operability into consideration such as adopting steel cables as transmission components and mass balances to eliminate the gravity effect and so on. The dynamics of haptic interface including actuating device is also studied. In order to provide operator with fidelity kinesthetic information, we design a force controller using self-learning fuzzy logic control. The simulation result verifies the effectiveness of the control method.


Higher education institutions now a days are operating in an increasingly complex and competitive environment. The application of innovation is a must for sustaining its competitive advantage. Institution leaders are using data management and analytics to question the status quo and develop effective solutions. Achieving these insights and information requires not a single report from a single system, but rather the ability to access, share, and explore institution-wide data that can be transformed into meaningful insights at every level of the institution. Consequently, institutions are facing problems in providing necessary information technology support for fulfilling excellence in performance. More specifically, the best practices of big data management and analytics need to be considered within higher education institutions. Therefore, the study aimed at investigating big data and analytics, in terms of: (1) definition; (2) its most important principles; (3) models; and (4) benefits of its use to fulfill performance excellence in higher education institutions. This involves shedding light on big data and analytics models and the possibility of its use in higher education institutions, and exploring the effect of using big data and analytics in achieving performance excellence. To reach these objectives, the researcher employed a qualitative research methodology for collecting and analyzing data. The study concluded the most important result, that there is a significant relationship between big data and analytics and excellence of performance as big data management and analytics mainly aims at achieving tasks quickly with the least effort and cost. These positive results support the use of big data and analytics in institutions and improving knowledge in this field and providing a practical guide adaptable to the institution structure. This paper also identifies the role of big data and analytics in institutions of higher education worldwide and outlines the implementation challenges and opportunities in the education industry.


Abstract A 6-week feeding trial was carried out to investigate the optimal calcium level in the diet of quail chicks in Nigeria. Four isonitrogenous (25% crude protein) diets containing 0.5, 1.0,1.5 and 2.0% dietary calcium were employed in the trial which involved 480) day-old, uncensored quail chicks. The diets were also isocaloric (2750 kcal/kg M. E). Each dietary treatment was replicated three times. Responses measured included weight gain, feed consumption and feed conversion ratio. Feed intake was higher in diet A (P<0.05) in comparison to others. Diet D recorded lower feed intake (P<0.05) than Diets B and C. Weight gain was similar (P>0.05) for Diets A, B and C which were better than diet D (P>0.05). Feed conversion was better with Diets C And D (P<0.05) than with diets A and B. Diet A was poorer (P<0.05) than diet B in terms of feed conversion. Feed cost/gain ratio was lower (P<0.05) on Diet A than others. Percent bone ash was similar on the diets except Diet C. Results of this study indicated that dietary calcium levels of between 0.5 and 1% will support acceptable weight gain and % bone ash in the first 6 weeks of life.


Various materials have been developed to restore sludge-accumulated bivalve fishing grounds. In this study, we examined the effectiveness of using an improved material, fluvic acid iron silica material ( FS material ) , to treat deteriorated sediment by the photo-Fenton reaction of Fe-humic substance complexation in Lake Shibunotsunai, northern Japan. From the results of a field experiment with FS material laid on the lake bottom, the thickness of deposited mud, mud content, and ignition loss of bottom sediment were partially reduced in the FS material site compared with the control site, but the effect was much smaller than in the previous research. Laboratory experiments revealed that the effectiveness of FS material was enhanced by a high water temperature and by using a greater amount of FS material. It has been found that if there is a current in the FS material site, the decomposed sediment surface layer may peel away. As a result, it is important to consider the applicable utilization method of FS material in accordance with the locality.


The requirement of integration of viral proteins into cell surface membranes of host cells for elicitation of anti‐Sendai virus (SV) cytotoxic T lymphocytes (CTL) has been investigated. The purified hemagglutinin‐neuraminidase (HN) and fusion (F) glycoproteins of SV incorporated into phospholipid vesicles was used to analyze this question. Phospholipid vesicles possessing an active HN and F glycoprotein were capable of eliciting both anti‐SV CTL and antibodies. However, the incorporation of an inactive F glycoprotein into HN‐containing vesicles or its absence from such vesicles resulted in stimulation of only anti‐SV antibodies and not anti‐SV CTL.


Thrips species composition and seasonal abundance were studied in winter wheat, Triticum aestivum L., and winter rye, Secale cereale L., during 3 seasons in the coastal plain region of Georgia. Thrips abundance also was examined in wild radish, Raphanus raphanistrum L., a common annual winter weed in small-grain fields. Limothrips cerealium (Haliday) and Frankliniella fusca (Hinds) were the 2 dominant species comprising >89% of the adult thrips collected in both crops. Frankliniella tritici (Fitch), F. bispinosa (Morgan), F. occidentalis (Pergande), F. williamsi Hood, Haplothrips graminis Hood and Plesiothrips perplexus (Beach) also were collected in low numbers in most years. Winter rye supported breeding populations of F. fusca during the autumn, winter, and early spring. Few thrips of any species were collected in winter wheat before spike emergence in March. However, large numbers of F. fusca and L. cerealium developed in wheat during the spring. Winter rye also served as a spring host for these thrips, but population increases were limited by grazing and early crop destruction. Differences in F. fusca phenology between wheat and rye probably are related to crop planting time in that rye for grazing is planted ≈6 wk earlier than wheat for grain production. Small grains grown for grain production presumably are planted too late for colonization by F. fusca in autumn. Although F. tritici , F. bispinosa , and F. occidentalis adults were present in the spring, these thrips probably did not breed extensively in wheat or rye. However, flowering wild radish in wheat fields supported large populations of F. tritici and F. occidentalis in late winter and spring. Therefore, winter small grains, particularly wheat, are important sources of F. fusca and L. cerealium that attack summer hosts. Small grains are not a major source of other Frankliniella spp., except possibly F. williamsi , but wild radish within winter small grains probably is an important spring source of F. tritici and F. occidentalis .


In this paper, tunneling effect of Cooper pairs in weak-link superconductor structure with multi-junctions under the condition for overstepping the Josephson approximation is discussed. The equations describing the electric current based on the tunneling effect of Cooper pairs in several kinds of weak-link superconductor structures with multi-junctions are obtained under the condition to overstep the Josephson approximation. For both SISISIS and a four junctions ring, when all junctions are in the zero voltage state, the exact solution of the equations is obtained. It is found that, because of the tunneling effect of the Cooper pairs, an alternating current exists which can be expressed by an elliptic function. For a four junctions ring, the relation between the period of the alternating current and flux is pointed out. At last, the condition for overstepping the Josephson approximation is discussed. The result shows that overstepping the Josephson approximation may be possible when the volumes of superconductors are small enough.


Geological science is a very comprehensive practical subject Geological experimental teaching is very important in the teaching system Using innovative management theory,this paper analyses the three basic functions of the experimental teaching and defines the relationship of the functionsThe paper invastigates the contents of innovation functions and their level position,and points out the conditions for the support of innovative functions and the approach for innovation


According to the CPC Central Committee and State Council to deepen the requirements of medical and health system,by analyzing the advantages and disadvantages of various forms of financial regulation,combined with the problems found in the actual work,the new health reform program implementation is discussed.Continuous improvement of the financial regulatory system means that health system and health development should constantly meet people's health needs.


ABSTRACT Revision to a higher amputation level is a common procedure most often necessitated by injury to the residual limb, infection, ulceration, incision dehiscence, or critical limb ischemia. It is possible that a patient could actually increase functional status after an amputation revision, and this report documents the functional status of an individual before and after an amputation revision from the transtibial level to the transfemoral level due to critical limb ischemia and suggests possible causes of his success. Three assessments, the Locomotor Capabilities Index with a 5-point scale (LCI5), Instrumental Activities of Daily Living (IADL), and Amputee Mobility Predictor with a prosthesis (AMPpro), were administered 1 month before the revision and 3 months later. His LCI5 score increased by 10 points, the AMPpro score increased by 9 points, and the IADL status remained constant. There are several factors that likely contributed to this patient's success as a transfemoral amputee. First, this patient was 49 years old, and his first amputation was the result of a trauma, so he had a statistical advantage over most amputees. Second, the patient was highly motivated and well supported by his family. Finally, the patient was treated by a multidisciplinary team of prosthetists, physicians, and physical therapists who regularly reviewed his goals and progress. With each of these factors in place, the patient actually increased his functional status after the amputation revision.


Abstract This paper discusses the consequences of EU migration control policies on irregular and transit migration in Turkey by focusing on African migrants. Our argument is that the EU's concern with transit migration through the Mediterranean and hence its externalization and securitization of migration control have contributed to Turkey's becoming a waiting room for irregular and transit migrants. Based on the findings of a survey with African migrants in İstanbul and analysis of secondary sources, we show that many African migrants get stranded in Turkey. In the absence of an institutional setup for migration management and the prevalence of a security approach, migrants are faced with humanitarian problems and human rights violations.


Kim, Hyeong Min; Kim, Yeon-Soo(2012), "A Study of the Features of Parsing in Different Linguistic Theories," Language & Information Society 18. According to the definitions of parsing in linguistic lexicons the term is generally defined as 'breaking sentence down into its constituents', 'syntactic analysis of sentence' or 'structure analysis of sentence' etc. The primary purpose of parsing is, in the traditional view, to analyze and understand the sentence structure in Western classical languages, above all in Latin and Greek. Based on its traditional use the parsing is primarily, up to now, utilized in investigating similarities and differences between natural languages and in foreign language education. But recently the application areas of parsing is much expanding. In the last half of the 20th century the parsing is going beyond the pure research fields dealing with structure analysis of sentences in human languages to the applied research fields which aims to make machines or computers understand human languages. In this context, computer linguistics and artificial intelligence are chiefly discussed. On the other hand, in psycholinguistics the parsing is used to disclose human


The RCA water quality model was incorporated with the sediment module and the light shading effect due to the high turbidity in the Pearl River Estuary (PRE). The modified RCA water quality model was then applied to the PRE. Results show that the modified RCA model can reproduce the distribution of nutrients,phytoplankton and dissolved oxygen (DO) in the PRE successfully,which means the modified model can capture the main processes of water quality in the PRE. In the wet season,huge amount of fresh water enters the PRE and results in a river plume. Particulate organic matter (POM) deposits intensely in specific areas of western and central shoal of the Lingdingyang Estuary and outside Modaomen as a result of the plumes. Furthermore,high deposition rate of POM in specific areas leads to high sediment oxygen demand (SOD),which coincides with the areas with strong stratification. High SOD and strong stratification lead to hypoxia. On the shelf areas,primary production increases as the suspended sediment concentration decreases,but the increasing primary production does not result in hypoxia as the marine particulate organic carbon (POC) spreads all over the shelf and the stratification is weak.


Most firms in Auckland are characterised by a structure which has broad, largely Polynesian base with a smaller totally white executive peak. Employers, as the principal gatekeepers controlling access to the resource of employment, have contributed to this imbalance by limiting the job opportunities available to the Pacific Islander. In relation to th1s, management needs to reassess its attitudes and practices, and the new Human Rights Commission Act may be a suitable incentive.


Let G be a locally compact group, and let P(G) be the convex set of all continuous, positive definite functions ø on G normalized by ø(e) = 1, where e denotes the group unit of G. For ø∈P(G) the spectrum spø of ø is defined as the set of all indecomposable ψ∈P(G) which are limits, for the topology of uniform convergence on compact subsets of G, of functions of the form (see [5], p. 43). Denoting by πø the cyclic unitary representation of G associated with ø, it is clear that sp ø consists of all ψ∈P(G) for which πψ is irreducible and weakly contained in πø (see [3], chapter 18).


Type of funding sources: None.

 Anorexia Nervosa (AN) is a psychiatric disorder that can lead to cardiac complications, especially in severely malnourished patients. Cardiovascular involvement includes autonomic dysfunction (increased vagal tone, bradycardia, orthostatic hypotension, syncope), arrhythmias, pericardial effusion, heart failure and sudden death. A few studies have examined the echocardiographic abnormalities secondary to AN, reporting mainly a decreased cardiac mass and an increased incidence of pericardial effusion. No previous studies examined the changes of Global Longitudinal Strain (GLS), which has been shown to be an early marker of myocardial damage in other subsets.

 This study aimed to characterize echocardiographic abnormalities in AN, and to assess impairment of global and regional longitudinal strain (LS) and its clinical value in this context.

 We prospectively enrolled 42 consecutive patients (1 male) admitted to a highly specialized AN unit between November 2020 and July 2021 with AN (Mental Disorders, 4th Edition-DSM IVr). We also selected 34 healthy controls, matched for age and sex. In all subjects, we reported the cardiac frequency, systolic and diastolic blood pressure, blood examinations, and we performed an echocardiography, including GLS measurement. Eighteen patients were treated with enteral or parenteral feeding. A subset of 26 AN patients performed a second echocardiography after one month of follow up; 14 of them received forced feeding.

 Compared with healthy subjects, AN patients had significantly lower albumin levels (45.1 ± 10.3 vs 66.0 ± 4.8 mg/dl, p = 0.031), lower FT3 levels (3.7 ± 1.0 vs 7.9 ± 6.4 pg/mL, p = 0.001), higher FT4 levels (13.8 ± 1.8 vs 9.6 ± 8.1 pg/mL, p = 0.008), a lower cardiac frequency (63 ± 18 vs 73 ± 12 bpm, p = 0.004), a higher incidence of pericardial effusion (9/42 vs 0/34, p = 0.008), a lower myocardial mass (62.3 ± 15.0 vs 98.5 ± 28.5 g, p < 0.001), a lower absolute value of GLS (-18.8 ± 2.8 vs -20.3 ± 2.0 %, p = 0.014) and basal LS (-15.4 ± 6.1 vs -19.6 ± 2.8 %, p < 0.001). The bull's eye mapping showed a plot pattern with blue basal areas in 17/42 AN patients vs 1/34 healthy subjects (p < 0.001). The 17 anorexic patients with a blue basal pattern needed forced feeding in a higher proportion (11/17 vs 7/25, p = 0.018) and presented more frequently amenorrhea (14/17 vs 11/25, p = 0.046). During the follow up (26 AN patients performed a second echocardiography), of 13 patients with blue areas in the first bull's eye mapping, 11 recovered a completely red pattern, and of 13 patients with a red bull's eye in the first examination, no one presented blue areas on the second one.

 GLS is significantly altered in AN patients and a basal blue pattern on bull's eye mapping individuates more severe cases. These changes seem to be reversible (Figure 1), although further studies are necessary to understand which factors influence this pattern besides BMI. Abstract Figure 1


This paper introduced a new kind of high-speed box-taking mechanism.Double cams five-bar combined mechanism is designed according to motion requirements by using the analysis of box-taking process of automatic cartoner.The actuator of this mechanism can satisfy action of box-taking completely and realize the trajectory with the demand of velocity and gesture.Analyze the key component and confirm the key parameter which affects the efficiency of box-taking.The interchangeable gascircuit also be designed.


Current AASHTO LRFD Bridge Design Specifications Service I deflection limits are in place with the purpose to prevent deformation-induced structural damage and psychological user discomfort from excess bridge vibration. Previous research has shown that deflection criterion alone is insufficient in controlling excess bridge vibrations and structural deterioration of the concrete deck. Previous research shows that natural frequency criteria better controls excess vibration than deflection criteria alone. In addition, previous research shows no significant correlation between deflection and structural deformation of the concrete deck slab. To better control excess bridge vibrations and deformation-induced structural deterioration, two new separate criteria formulations are proposed. The first formulation consists of a natural frequency criteria transformed into deflection-type terms familiar to the typical bridge engineer. The second proposed formulation directly controls the acting flexural strain in the concrete deck to control deformation-induced structural damage. The proposed serviceability criteria are applied to a database of 185 steel girder bridges. Both the as-built behavior and the design optimized behavior are examined and compared with current AASHTO serviceability criteria. The proposed user comfort and deformation-induced damage serviceability formulations are intended to be incorporated into ongoing Federal Highway Administration and bridge industry long-term bridge performance research where serviceability criteria is an important component.


SUMMARY For establishment of cytological diagnostic criteria of inflammatory colorectal polyp (ICRP) in miniature dachshunds (M. dax), cytological specimens of 16 cases of ICRP of M. dax (ICRP group) and 53 cases of a non h ICRP group including normal mucosa, inflammatory diseases and neoplastic diseases were analyzed. In 12 cases of the ICRP group (75.0%), significantly more multinucleated giant cells (MGCs) were detected than those in the non h ICRP group (only one case, 1.9%). Sensitivity, specificity, positive predictive value and neg-ative predictive value of cytological detection of MGCs in cytological specimens to diagnose ICRP were 75.0%, 98.2%, 92.3% and 93.2%, respectively. In conclusion, detection of MGCs in colorectal cytology of M. dax is use-ful for cytological diagnosis of ICRP.


Introduction: Tumor necrosis factor-alpha (TNF-α) is a proinflammatory mediator considered to be a soluble mediator released from immunocompetent cells. It exercises a wide range of proinflammatory and immunomodulatory effects in different cell populations, such as stimulating prostaglandin synthesis, promoting tumors in a variety of cancers, producing proteases, and activating osteoclastic function and therefore bone resorption. Its myriad functions suggest that TNF-α plays an important role in mediating the immune-inflammatory responses initiated by infection or other types of damage.
Aim: The aim of the present study is to evaluate the concentrations of Tumour Necrosis Factor- alpha (TNF- α) in the saliva of periodontitis patients with or without diabetes mellitus.
Materials and methods: A total of 30 participants were taken and divided into 3 groups with each group consisting of 10 saliva samples from patients with clinically healthy gingiva and patients with chronic periodontitis with diabetes mellitus and periodontitis patients only. Saliva sample was collected and salivary TNF- α was done using Enzyme Linked Immunosorbent Assay (ELISA). Statistically analyses was done by one way ANOVA test
Results: Salivary TNF- α concentration in periodontal health, periodontitis with diabetes mellitus (P+DM), Periodontitis only (P) were analysed.  Salivary TNF- α concentration was found to be significantly higher (p<0.05) in periodontitis with diabetes mellitus (49±3.5 pg/ml) when compared with periodontitis only (29±3.6 pg/ml) and also when compared with healthy controls (17±1.4 pg/ml).
Conclusion: The present study showed elevated TNF- α in periodontitis patients with diabetes mellitus when compared to patients with periodontitis only and normal healthy patients. Further studies are required in a large scale to substantiate the role of TNF-α in the progression of periodontal diseases.


Welcome to the final issue of Volume 39! We hope the fall semester is going well for you and your students. We also hope you plan to attend the TED fall conference in Lexington, KY. We are excited to share that Teacher Education and Special Education (TESE) has received its first impact factor this past summer. The TESE publication is now indexed and abstracted in (a) Social Sciences Citation Index®, (b) Journal Citation Reports/Social Sciences Edition, and (c) Current


Background and Objectives This study aims to assess the frequency of positive lumbosacral magnetic resonance imaging (MRI) results in patients with non-traumatic low back pain (LBP) based on the specialty of the referring physician. Subjects and Methods In this retrospective study, 335 patients with non-traumatic LBP aged >18 years participated. Their demographic information and MRI findings and the specialty of the referring physician were extracted and recorded from the imaging information system of a hospital. Frequency of positive lumbosacral MRI results based on the specialty of the referring physician were compared. To avoid bias, the MRIs with a same imaging protocol were selected, and reporting was done by a same radiologist. Results Of 335 patients, 145(43.3%) were male and 190(57.6%) were female. Among the referring physicians, 139(41.5%) were neurosurgeon, 114(34%) were orthopedists, 61(18.2%) were neurologists, and 21(6.3%) were physical medicine specialist. There was no significant difference in positive MRI results between different specialties of the referring physicians (P>0.05). Conclusion There is no difference in the frequency of positive lumbosacral MRI results in patients with non-traumatic LBP treated by orthopedics, neurologists, neurosurgeons, and physical medicine specialists.


BACKGROUND
It has been suggested that the current staging system does not accurately reflect survival outcomes for advanced bronchiolo-alveolar carcinoma (BAC) patients.

METHODS
We conducted a case-only analysis of US Surveillance, Epidemiology, and End Results (SEER) data (1998-2002). Overall survival (OS) and lung cancer-specific survival (LCSS) univariate analyses were conducted using the Kaplan-Meier method. Multivariate survival analyses were performed using Cox proportional hazards ratios.

RESULTS
2345 incident cases of BAC were analyzed, including 707 patients with stage IIIB or IV BAC. Patients with stage IIIB BAC due to multiple lesions in the same lobe (n=93) had significantly improved median OS (46m) and LCSS (>58m) compared to other stage IIIB BAC patients (n=111; OS=9m, P<0.0001; LCSS=10m, P<0.0001). Among stage IV BAC patients, those with intrapulmonary metastasis (n=278) had significantly improved median OS (13m) and LCSS (15m) compared to those with distant metastasis (n=225; OS=7m, P<0.0001; LCSS=7m, P=0.0001). These survival differences persisted after adjustment for age, gender, ethnicity, and surgical treatment status.

CONCLUSIONS
Among stage IIIB and IV BAC patients, those presenting with ipsilateral intrapulmonary metastasis have improved survival outcomes. Our results add further support for modification to the current staging system for BAC.


Demand and supply balancing is the key technology for power management and high-efficiency planning. As the smart metering device is getting popular in the Japan, USA and EU, the more data from smart meter can be collected for the better forecast. Forecast based on the Top-Down versus Bottom-Up was a long-term discussion for various fields. We performed a short-term power demand curve forecast based on Gradient boosting machine to compare the two methods. We found that there is very slight advantage of the bottom-up method in the demand forecast just based on the demand data.


Increased bone density disorders are the result of a disequilibrium between the osseous production and the resorption. Among them, Camurati-Engelmann disease ( CED ) is an autosomal dominant sclerosing bone dysplasia with an incomplete penetrance. We have confirmed that Camurati-Engelmann is a genetically homogeneous condition and have identified three distinct mutations in exon 4 of the TGFβ1 gene in 7 familes. We have excluded the role of TGFβ1 polymorphisms in the clinical variability of CE. We have also studied the group of osteopetrosis, which include at least eight distinct conditions, namely the malignant autosomal recessive form ( ARO )


To increase the competency of undergraduate nursing students to find and evaluate online health information, a Digital Health Assignment was created for second year nursing students. Facebook was used as the assignment platform. Students chose and appraised social media postings regarding topics of interest for expecting families. Students utilized an adapted Trust in Online Health Information scale to appraise the social media postings, including the quality of information. At completion of the assignment, student evaluation surveys revealed the knowledge gained through the learning activity. Implications for nursing education are suggested.


The article deals with the issues of active teaching methods that contribute to increasing the intellectual activity of students. The proposed elements of the lessons will help to develop motivation for learning, learn to independently acquire knowledge, increase interest in the subject.


Fast, efficient and robust algorithms are needed for real-time visual tracking that could run smoothly onboard airborne embedded systems. In order to efficiently use a motion-detection-based tracking algorithm on a raw image sequence captured by a moving platform, the relative motion between the camera and the ground plane must be stabilized first so that only the real moving objects in the scene could be detected. Using point correspondences to estimate the homography matrix between the frames is a common registration method used for the stabilization. In order to have a valid homography estimation, most of the point correspondences between the images have to lie on the same 3D plane (i.e. ground plane). However, when the scene includes multiple complex 3D structures (e.g. trees, cloudy sky, buildings) it becomes extremely challenging to satisfy this constraint, particularly for aerial images acquired from a low altitude flying drone with an oblique camera angle imaging a scene in which the ground plane is not the dominant object. In this work, we propose the Short-term Ground Plane-based Stabilization (SGPS) algorithm, a robust video stabilization algorithm that registers short video segments using the ground plane information to efficiently stabilize oblique aerial image sequences captured by low-altitude flying UAvs. Our experiments show satisfactory results when compared to registration without plane segmentation on the same type of raw videos.


For many years members of our Society and scores of others here and abroad, with generous financial aid from many sources, have pursued research and published the results in miniscule detail. Many also have worked abroad in various public health and medical programs. The ultimate goal was to unravel Nature's secrets and benefit mankind, especially in the less developed parts of the world. The "rich" U.S. Government, 400 billion in debt, scores of foundations, solvent World Health Organization, industry, and the Church have participated in these activities. It is of these matters that I will speak after some 47 years of observing and participating in them. I shall give names of persons and countries only in connection with successes.
At the age of 24 I was the minor member, the Benjamin, of a hookworm research group, Rockefeller-supported, on the way to Nicaragua.