[Objective]This study analyzed the tea polyphenol content in Yunnan Mengku large-leaved Pu'er tea to provide theoretical basis for the intense processing of food developments and functions. [Method]National tea tasters were invited to sensory evaluate eight Pu'er tea samples (raw tea and ripe tea) from the Yunnan Mengku large-leaved species, and then the tea polyphenol content was determined by the ferrous tartrate method. [Result]The sensory quality and the aging degree of raw tea and ripe tea were obviously different. Meanwhile, the tea polyphenol content of raw tea and ripe tea from the same brand showed apparent decreasing trend as the tea storage time prolonged. The tea polyphenol content of raw tea and ripe tea from the same year were also obviously different, with the tea polyphenol content in raw tea being 2.8-5.4 times higher than that in ripe tea. [Conclusion]Due to the different processing technology, there were significant differences between the aroma, taste, liquor color, and tea polyphenol content of Yunnan Mengku large-leaved Pu'er raw tea and Pu'er ripe tea. Furthermore, the tea polyphenol contents of both raw tea and ripe tea decreased as the storage time prolonged.


We have studied the nonlinear conductivity and the accompanied broad band noise of monoclinic TaS 3 . The noise voltage becomes maximum just above the threshold field E T of the nonlinear conduction. For comparison, the same measurements were made for NbSe 3 and the similar results were obtained. The generation of broad band noise is explained in terms of two valued process, and the number of degrees of freedom of the CDW motion, N , is estimated to be 10 9-10 /cm 3 in both of monoclinic TaS 3 which is semiconducting at low temperatures, and NbSe 3 which is metallic. This result indicates that the motion of the CDW's is not described as that of a rigid body. N is found to decrease with decreasing temperature in monoclinic TaS 3 .


In Arabs and Iranians in the Islamic Conquest Narrative, Scott Savran explores how Muslim historians, writing primarily during the period 750–1050 in both Arabic and Persian, came to terms with and gave meaning to the Arab conquest of Iran. Savran examines these issues through a study of representations of Arab-Sassanian relations in Islamic historical writing. Early on, the author argues for two primary phases of narrative construction that coincide with two periods of identity formation under the 'Abbasid Caliphate. The first focuses on the creation of a unified Arab identity which Savran argues was constructed in response to the growing influence of Iranian culture on the 'Abbasid court and society as well as to counter the Shu'ubiyya "movement." In this vein, the "Arab versus 'ajam" discourse found in descriptions of Arab-Sassanian relations embodied "a dialogue between two competing visions of Islamic civilization," one modeled off the socially stratified absolute monarchies of Near Eastern empires and the other inspired by the austere egalitarianism of pre-Islamic tribal Arabia. The second phase emerged in the late ninth century, at the outset of the "Iranian Intermezzo," when historians of Iranian descent integrated pre-Islamic Iranian history into a broader Islamic salvific history by which Iranians could – through conversion to Islam and acknowledging the faults of their Sassanian forbearers – rise again to their rightful place at the front of a world empire. In chapters 1 and 2, Savran lays out these arguments along with his theoretical approaches and methodologies. He engages the concept of "collective memory" and emphasizes its role in shaping group identity through the writing of historical narratives, invoking the theories of Maurice Halbwacks and Hayden White. In recent years, questions of memory and identity have become increasingly important to the study of the early and medieval Islamic historical tradition and Savran MESA R o M E S 53 1 2019


At present, China's road traffic safety situation is grim, so how to effectively curb traffic accidents is an urgent problem to be solved. Vehicle safety is the main body of road safety and monitoring and early warning the whole process of vehicle driving is an effective way to improve driving safety and reduce accident rate. In this paper, the comprehensive application of multi-source sensors is taken as the means, and the processing and analysis of associated big data is taken as the basic method. Firstly, the key factors affecting road traffic safety are analyzed, and based on this, the sensor selection is realized. Secondly, the system architecture is studied and the software and hardware design of the system are completed. Finally, the field vehicle experiment is carried out, the typical experimental data are analyzed, and the prototype system verification is completed. The system has been linked with the big data system of the traffic police in Hunan Province currently, and conducted a joint test for the intercity bus and vehicle carrying dangerous goods, laying a foundation for effectively improving the safety of vehicles and roads.


The aim of this project is to scrutinize the effect of blend solid fuels consisting of charcoal, arecanut leaf and husk on calorific value. While arecanut leaf and husk are processed from natural plants. A significant increase in calorific value obtained when charcoal, arecanut leaf and husk with a proper ratio of mixing. To increase the availability of charcoal by using the solid bio waste like arecanut leaf and husk. It is easily available and the cost of this waste should be low compared to other fuel. It has high calorific value than other bio solid waste. It needs some preparation process before the combustion, which is mainly done for proper combustion. That fuels initially have the various size in nature, it is not effective for complete combustion so it will size before the combustion process. The ash content of the charcoal should higher than other fuel so the combination of these two fuel should give low ash and also cost. It is used in the application of steam dryer for drying cardamom and tea leaf. Keywords--Arecanut Leaf, Blending, Calorific value, Ash.


Introduction:
 Nebraska Mission: Lifeline Stroke is a 4-year initiative to increase guideline-based treatment of acute stroke across the continuum of care. Guidelines advise post-stroke assessment by a multi-disciplinary team to guide discharge process and select ideal rehab setting.

 Purpose:
 To develop resources to facilitate the transition of Nebraskans with stroke to the most appropriate level of post-acute care.

 Methods:
 Healthcare Providers (HCPs) from various settings completed two surveys: hospital stroke rehab referral strategies and practices (N=23), and individual experiences related to stroke rehab (N=260). In addition, a literature review was conducted to find published guidelines and research on clinical decision making. Lastly, a focus group consisting of social worker/case managers was held to provide input on resources developed.

 Results:
 Hospitals (N=23) believe higher numbers of stroke patients should be referred to IRFs (42%) and stated that patients' "health status" (91%), "opinions from hospital team members" (87%), and "opinions from patient, family, or caregivers" (78%) are most relevant in the decision process. Factors that impact referral process include: HCPs may not be familiar with all options for post-acute rehab care (17%) and patient or family/caregivers are not educated about options (30%). Most (57%) of HCPs surveyed and all focus group participants indicated discharge referral process could be improved with a standardized decision-making tool. Based on this input, two discharge planning guides were developed. The first assists HCPs in determining appropriate level of post-acute stroke care by comparing various types and settings in an easy-to-read format. The second is patient/caregiver focused and includes information to assist in decision-making process and a table comparing rehab settings. These guides have been disseminated through conference presentations, direct mailings, and web-based resources.

 Conclusions:
 Discharge tools with clear descriptions of options are necessary to assist HCPs and patients/caregivers in matching appropriate care with patient's rehab needs. These care choices are key to patients achieving their highest level of independence.


A 37-year-old man presented to the emergency department with severe respiratory distress. He reported a history of hypertension, diabetes and end-stage renal failure for which he received hemodialysis three times per week. However, he admitted to missing his last two dialysis sessions. The patient was diaphoretic and in obvious respiratory distress. His vital signs were notable for a respiratory rate of 32/minute, pulse oximetry of 80% on room air, heart rate 70/minute, blood pressure 190/100, afebrile, and his fingerstick glucose was 200. He had obvious jugular venous distension and rales on lung auscultation. The rest of his exam was unremarkable.


The authors develop a one-period model of hospital and donor behavior to analyze how insurance for hospital care, various public subsidies, and other factors affect donations to hospitals. Theoretically, increased insurance coverage has an ambiguous effect on private giving. Empirical tests using time series and cross-sectional data show that the growth of private insurance, and especially the introduction of Medicare and Medicaid, substantially reduces private giving to hospitals. Effects of public subsidies for construction depend on whether the subsidy more closely resembles a matching or lump-sum grant. Coauthors are Thomas J. Hoerger, Michael A. Morrisey, and Mahud Hassan. Copyright 1990 by Oxford University Press.


This paper points out that the integrated problem of entrance on ramp control, mainline control and corridor control must be studied in order to solve traffic jam of freeway effectively. The integrated control framework of entrance ramp metering, mainline control and corridor control based on multi agent is proposed after the characteristics of multi agent and traffic flow process in the freeway are analyzed. As the key problems, short term traffic flow forecasting and the communication between the agents are stated.


Chronicmyelogenous leukemia (CML) is driven by the Bcr-Abl fusion protein, which is a result of a (9;22) chromosomal translocation. Imatinib, dasatinib, and nilotinib (tyrosine kinase inhibitors, TKI) have revolutionized how CML is treated. Although the majority of patients respond to these kinase inhibitors, a subset becomes resistant to these therapeutics. Synribo (omacetaxine mepesuccinate) was recently approved by the U.S. Food and Drug Administration for Philadelphia-positive CML either in the chronic or the accelerated phasewhose disease failed two prior TKIs.With omacetaxine 1.25mg/m twice daily for 14 days during induction and for 7 days during maintenance, a major cytogenetic response occurred in 20% of patients in the chronic phase and major hematologic response in 27% of patients in the accelerated phase. Laboratory investigations unraveled themechanism of action and effectiveness of this agent. Bcr-Abl protein is intrinsically programmed to turn over with a short half-life that makes it susceptible to protein translation inhibitors.Omacetaxine (homoharringtonine) inhibits total protein biosynthesis by binding toA-site cleft of ribosomes.As a corollary to this action, there is adiminutionof short-livedproteins, suchasBcr-Abl, followed by cell death. Approval of this first-in-class protein translation inhibitor opens up new avenues for its use in other diseases as well as mechanism-based combinations. Clin Cancer Res; 20(7); 1735–40. 2014 AACR.


Phosphorene, also referred to as phosphorus‐based elemental material (black and red), display unusual electronic‐structure characteristics, which can significantly enrich the fields of energy application and possesses huge potential in photocatalysis owing to its bandgap tunability, high optical absorption, large surface area, high charge carrier mobilities, and efficient solar to chemical energy conversion. However, due to chemical instability and the poor visible‐light utilization efficiency, individual phosphorus materials cannot promote charge transfer and separation. For designing active photocatalysts, phosphorus‐based hybrid materials with effective charge carriers separation at the heterojunction interface has played significant role. In this respect, considerable attempts have been made to fabricate black–red phosphorus heterostructure for photocatalytic applications and solar fuel generation, such as photocatalytic and electrocatalysis water splitting, CO2 reduction, carbohydrates synthesis, etc. This review article highlights the strategies for the synthesis of black–red phosphorus heterostructure materials for catalysis with a special focus on their potential for solar fuel generation applications. Recently developed black–red phosphorus heterostructure will be discussed, which can improve the most challenging drawback of phosphorus materials. Finally, the major challenges along with future trends of black–red phosphorus heterostructure in catalytic applications are outlined.


New observations of linear polarization in the UBVRI system for six bright northern Be stars are combined with existing measurements from two previous epochs in an analysis of long-term variation over nearly two decades. No indication of large short-term variability is found within the individual data sets, but ζ Tau and π Aqr have shown steady change on the longer time scale.


The interrogation analysis of digital PlY images with low pixel resolution is investigated analytically. It is demonstrated that the minimum required sampling rate for PlY images is about 1/4 of the sampling rate that matches the optical bandwidth of PlY imaging optics; a further increase of the sampling rate does not improve the accuracy of the estimated image covariance. The accuracy of a centroiding ( "center-of-mass" ) estimator and a curve-fitting ( "Gaussian-fit" ) estimator for the particle-image displacement is evaluated. It appears that the estimated displacement is always biased, as a result of the fact that the image covariance is estimated from a finite number of samples. The proposed correction procedure adequately compensates for this bias. The predicted performance of the displacement estimators is in fair agreement with the results obtained from measurements of a linearly displaced test object.


The aim of this paper is that the study of laminar boundary layer flow on an Isothermal wall/adabatic wall. The present study of this paper deals with two dimensional laminar boundary layer equation with steady state motion using similar transformation. The equation has been solved by Runge-Kutta method and Shooting technique. Results have been discussed by numerical solution and graphical representation.


Software architecture degradation is a longstanding problem in software engineering. Previous studies have shown that certain code anomalies - or patterns of code anomalies - are likely to be harmful to architecture design, although their identification is far from trivial. This study presents a system for not only detecting architecturally-relevant code anomalies, but also helping developers to prioritize their removal by ranking them. We detect code anomaly patterns based on static analysis that also exploit architecture information.


Suppose G=(V, E) is a graph and p ≥ 2q are positive integers. A (p, q)‐coloring of G is a mapping ϕ: V → {0, 1, …, p‐1} such that for any edge xy of G, q ≤ |ϕ(x)‐ϕ(y)| ≤ p‐q. A color‐list is a mapping L: V → $\cal P$({0, 1, …, p‐1}) which assigns to each vertex v a set L(v) of permissible colors. An L‐(p, q)‐coloring of G is a (p, q)‐coloring ϕ of G such that for each vertex v, ϕ(v) ∈ L(v). We say G is L‐(p, q)‐colorable if there exists an L‐(p, q)‐coloring of G. A color‐size‐list is a mapping ℓ which assigns to each vertex v a non‐negative integer ℓ(v). We say G is ℓ‐(p, q)‐colorable if for every color‐list L with |L(v)| = ℓ(v), G is L‐(p, q)‐colorable. In this article, we consider list circular coloring of trees and cycles. For any tree T and for any p ≥ 2q, we present a necessary and sufficient condition for T to be ℓ‐(p, q)‐colorable. For each cycle C and for each positive integer k, we present a condition on ℓ which is sufficient for C to be ℓ‐(2k+1, k)‐colorable, and the condition is sharp. © 2007 Wiley Periodicals, Inc. J Graph Theory 55: 249–265, 2007


ABSTRACT Hepatitis A virus (HAV) is shed in feces but also in saliva. HAV RNA was detected in saliva in five out of six acutely infected patients with HAV viremia. Serum and saliva sequences were identical. The simplicity of obtaining material allows the recommendation of the use of saliva for investigation of outbreaks.


Air separation equipment is just beginning to find use in compost production, with operators installing equipment to remove plastic from overs resulting from end product screening.


HfO2 and SiO2 single layer is deposited on glass substrate with plasma ion assistance provided by Leybold advanced plasma source (APS). The deposition is performed with a bias voltage in the range of 70-130 V for HfO2, and 70-170 V for SiO2. Optical, structural, mechanical properties, as well as absorption and laser induced damage threshold at 1064 nm of HfO2 and SiO2 single layer deposited with the plasma ion assistance are systematically investigated. With the increase of APS bias voltage, coatings with higher refractive index, reduced surface roughness, and higher laser-induced damage threshold (LIDT) are obtained, and no significant change of the absorption at 1064 nm is observed. For HfO2, a bias voltage can be identified to achieve coatings without any stress. However, too-high bias voltage can cause the increase of surface roughness and stress, and decrease the LIDT. The bias voltage can be properly identified to achieve coatings with desired properties.


To determine the impact of cyclooxygenase-2 (COX-2) expression on clinical behavior in irradiated and non-irradiated rectal carcinomas. Tumor samples were collected from 1231 patients of the Dutch TME trial in which rectal cancer patients were treated with standardized surgery, and randomized for pre-operative short-term (5 times 5Gy) radiotherapy or no pre-operative radiotherapy. Tissue micro arrays were constructed from primary tumor material and COX-2 expression was assessed by immunohistochemistry. Tumor cell apoptosis was determined by M30 immunostaining. A high level of COX-2 expression after radiotherapy was associated with low levels of tumor cell apoptosis (p=0.001). COX-2 expression had no significant impact on patient survival or tumor recurrence in non-irradiated tumors. However, in patients receiving preoperative radiotherapy, high level of COX-2 expression was associated with higher incidence of distant recurrences (p=0.003, HR: 1.7, CI: 1.2-2.5), and shorter disease free survival (p=0.002, HR: 1.5 CI: 1.2-2.0) and overall survival (p=0.009, HR: 1.5, C.I.: 1.1-2.0), independent of patient age, tumor stage, tumor location or the presence of tumor cells in the circumferential resection margin. A high level of COX-2 expression following preoperative radiotherapy in resection specimens is associated with apoptosis resistance, high distant recurrence rates and a poor prognosis in rectal cancer.


These popular and proven workbooks help students build confidence before attempting end-of-chapter problems. They provide short problems and exercises that focus on developing a particular skill, often requiring students to draw or interpret sketches and graphs, or reason with math relationships.


Presents a new automatic train protection system. Such messages as the distance to the preceding train or the speed restriction on switches are transmitted to each train instead of the limit speed set for the train. This is done through the rails using digital codes. An on-board processor generates a braking pattern using these messages and the braking performance. And if the speed exceeds the calculated value, the brake is applied. As this system controls the train speed in one step from full speed to stop, it can shorten the train headway. And it can effectively cope with a mixture of trains with different braking performances.<<ETX>>


Set the Chinese text sets into two classifications and determine whether the information is in the field of Chinese maritime by a two-classifier which is guided by multiple semantic. Eventually it gets Chinese maritime information set so that we can custom maritime information. We call this information system for the Chinese Marine engine. Experiments show that the Chinese Marine engine achieves good effects of custom the Chinese maritime information and it has a high practical value.


The stability of resonant states in Helium-like atoms while under the influence of a plasma environment is studied. We analyze the variation of resonance parameters (energies and lifetimes) against the strength of the screening parameter within the Debye-Hückel model. We use a Feshbach-like projection formalism with explicitly correlated CI-wave functions to uncover the evolution of resonance parameters until they cross the upper Aq+(N=2) threshold, and a complex scaling method to analyze the survival of these Feshbach resonances across the threshold, which eventually makes them behave as shape resonances.


300 ten-day aged quails(half of male and female) were randomly divided into 5 groups,in which 4 experiment groups and 1 control group,each group included 60 birds(each sex was 30).And the experiment birds receipted treatment with different irradiation doses(time) of ultraviolet by same wavelength.The ultraviolet radiation sources were from 15W ultraviolet B radiation(UV-B) lights.4 experiment groups were continuously irradiated for 1hour(1.4 μW·h/cm2),2 hours(2.8 μW·h/cm2),4 hours(5.6 μW·h/cm2) and 6 hours(8.4 μW·h/cm2) each day,respectively.The control group was not irradiated by ultraviolet radiation.The trial kept 4 weeks.The body weights and their gains of different groups were compared.The results showed that the body weights and gains of the 4 experiment groups were significantly higher than those of the control group(P0.05 or P0.01),and the 4 hour of UV-B irradiation(5.6 μW·h/cm2) per day was the best dose for increasing the growth of body weight.


Capacity building—the creation of innovative societies—is easier said than done. This process depends on a number of factors, especially the existence of well-functioning universities (i.e., that create the necessary human capital and are important components in the connection between science, technology, and society). The field of optics and photonics provides an excellent opportunity for many countries in the developing world to advance their focused research and development activities. For such focus on optics and photonics to be successful, however, there needs to be a steady inflow of good students (who have an interest in science) into the universities. Moreover, once these students are enrolled, it is important to steer them toward academic programs in the sciences and to keep their interests pointed in that direction. In other words, what can be done to make sure that these students (especially those that are naturally bright, creative, and motivated, and who could potentially follow any academic subject they want) are not chased away? Furthermore, once these students are committed to the study of optics and photonics, how can they best be prepared for a research-oriented career? It is also important to consider how to train students who take undergraduate physical science courses in their first year, but who plan to pursue a career outside the sciences, as critical thinkers who can contribute to the larger discussion that surrounds technological approaches to societal challenges. In traditional university education, teachers develop lectures that bring about conceptual understanding (i.e., as a result of expert and clear explanations). Unfortunately, such successful outcomes are rare. Indeed, results from physics education research (a field in which the effectiveness of various teaching methodologies for aiding students' understanding of basic concepts Figure 1. Undergraduate students at Quaid-i-Azam University (Islamabad, Pakistan) taking part in inquiry-based learning activities in the subject of optics and photonics.


The effective removal of heavy metals from the sugar industry is the most important issue of the many industrialized countries. Removal of Zn 2+ from Sugar cane effluent where studied using borassus flabellifer fiber. Batch adsorption was performed as a function of pH, initial metal ion concentration, equilibrium time and bio-sorbent dose. The optimum pH obtained from results found to be 5. The maximum contact time for the equilibrium concentration is 60 minutes. The biosorbent dose is 6g. The maximum efficiency of removal of metal ion by bio-mass is 77 % .The results are fit exactly by both Langmuir and freundlich isotherm model.


Aim: To evaluate the predictive value of preoperative ratio of neutrophils to lymphocytes (NLR) in distinguishing between benign and malignant masses, as inflammation plays a significant role in the development and emergence of cancer.
Material and Method: This retrospective study included 155 patients who underwent surgery due to an adnexal mass between December 2020 and December 2021 (55 were malignant, 100 were benign). Age, parity, tumor stage, chemotherapy, CA 125, CRP, neutrophils, lymphocytes, NLR, were recorded. The Mann-Whitney, the Chi-square test and multiple linear regression were used. The cut-off values of the variables were determined by calculating the areas under the receiver operating characteristic curve (ROC) for the purposes of differential diagnosis in the presence of malignancy, and by analyzing the sensitivity, specificity, positive predictive value, negative predictive value, and likelihood-ratio (LR) (+) values. A P-value of 2.79 for NLR; sensitivity was found to be 59.36%, specificity 75.51%, positive predictive value (PPV) 58.44, negative predictive value 75.58, LR (+) value 2.3. At cut-off> 36.9 for CA-125; sensitivity was 80.00%, specificity was 78.63%, positive predictive value was 67.72%, negative predictive value was 87.53%, LR (+) value was 3.73.
Conclusion: The primary outcome of our study is that the likelihood of malignancy in a patient with an NLR value of>2.79 is 2.3 times higher than in a patient with an NLR value of 36.9 is 3.73 times higher than in a patient with a CA-125 value of


A performance comparison between a compressive receiver and a wideband radiometer using sine waves and binary phase-shift-keyed (PSK) signals for the detected waveform is presented. The results indicate that the compressive receiver outperforms the radiometer in detecting the presence of a sine wave. The results also show that the compressive receiver exhibits superior performance when the input contains a binary PSK signal and the system is operating under the conditions of low input signal-to-noise ratio and low probability of false alarm.<<ETX>>


The main problem found in Alue Ie Puteh Village is the large number of vacant land used as waste disposal sites; this is due to the lack of integrated waste management sites. This activity was carried out at the Village Hall by inviting elements of the surrounding community. The socialization and discussion of the Farming Integrated System For Zero Waste program cover the program as a whole; in this case it involves the process from the beginning to being sustainable. We the implementing team of the Biology Study Program, initiated a community service program as a program community empowerment through empowerment in utilizing organic and plastic waste to be applied to activities that include the manufacture of probiotics, the production of hydroponic devices, maggot cultivation and the manufacture of liquid organic fertilizers. Furthermore, these products used to support aquaponic cultivation assistance activities where hydroponic cultivation systems integrated with tilapia fish farming systems.


Tomato (Solanum lycopersicum) is rich in anthocyanins, which are polyphenolic pigments. This study aimed to analyze and characterize the anthocyanin composition in cultivated blue tomato in Japan. The extracts of peel, seed, and pulp of tomatoes were purified following which anthocyanins and lycopene contents were analyzed using high-performance liquid chromatography and electrospray ionization mass spectrometry. Eleven types of anthocyanins were identified, including delphinidin, petunidin, and malvidin. Further, the antioxidant activity of anthocyanins was evaluated using 2,2′-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) diammonium salt radical quenching assays and electron spin resonance. "Blue tomato" extracts exert antioxidant activity. Thus, we showed that petunidin was present in the "blue tomato" peel while lycopene was present in the peel and pulp. Additionally, the blue tomato peel extract was found to significantly inhibit H2O2-induced cell death in vitro. This is the first study on cell protective effects of Japanese blue tomato extract and petunidin in murine photoreceptor cells. Graphical abstract This is the first study that shows qualitative and quantitative chemical characterization of the individual components responsible for the bioactivity of blue tomato extracts.


Multiple reflection effect between the antenna under test and probe in a near field measurement scenario is investigated and the direct portion of the transmission coefficient is extracted by applying the linear interpolation to the sampled data in the frequency domain. The obtained results are compared to a reference in terms of transmission coefficient and radiation pattern. It is shown that by utilizing this technique, the accuracy of the computed radiation pattern can be improved in different observation angles.


Abstract : The paper deals with a system of linear inequalities in a finite dimensional space. When the system is inconsistent, we are interested in vectors that satisfy the system in a least-squares sense. We characterize such least-squares solutions and propose a method to find one of these solutions. It is shown that for any given system of linear inequalities and for any starting point, the method can produce a solution in a finite number of iterations. Computational results are very satisfactory in terms of accuracy and number of iterations. (Author)


Introduction A comprehensive research on I35 large tracts of prairie was completed in I933 after five years of study. These tracts were distributed over an area of 60,ooo square miles, including the eastern one-third of Nebraska, the western one-third of Iowa, and adjacent areas in the four neighboring states (2). This investigation furnished the background for an understanding of the profound changes which have occurred during the several years of the great drought, which first became pronounced in I934. The response of prairie to the drought of that year has been discussed (3). Likewise, a detailed account of the destruction caused by the drought years of I934 and I935 and resultant changes and shifting of populations in both true and mixed prairies have been recorded (I). Research has been continued from season to season throughout the long period of abnormally low rainfall. Continuous records of climatic and edaphic factors have been obtained, and changes in behavior and structure of vegetation intensively studied. These have been recorded in detail by means of scores of permanent quadrats scattered widely from eastern Nebraska to western Kansas. With successive years of drought further deterioration has occurred. Favorable precipitation during the spring and early summer of I938 (and during I937 in certain portions of the area) has brought about important early stages in recovery. Several years with normal or excess precipitation, however, must intervene before the general trends toward readjustment are clearly seen. The purpose of the present paper is to summarize some of the more important changes which have occurred since I935.


From the 20th century on,great changes have been taking place in English vocabulary.The paper aims at illustrating the development of modern English vocabulary by the analysis of the causes of changes,word-formation approaches of new words and characteristics of latest vocabulary development.It would be helpful in mastering the streams and outline of English vocabulary development.


Springate-Baginski, O. and Wollenberg, E. (eds.) 2010 REDD, forest governance and rural livelihoods: the emerging agenda. CIFOR, Bogor, Indonesia.
Workshop participants included researchers from the Center for International Forest
Research (CIFOR) and UEA, and REDD experts from six focus countries: Brazil,
Indonesia, Madagascar, Tanzania, Mexico and Nepal


From 1977 to 1980, several research cruises were carried out in the coastal waters of Mozambique to collect oceanographic data. The distribution of hydrographic and bathythermograph stations is given. The water masses and circulation were mapped and wind data gathered.


The need of collecting information about business units grows together with economic progress. Accounting is the source of this data without which no company would be able to conduct business activity. The data is considered to be the business language home and abroad, because it represents all the financial results by means of figures. The financial and accounting systems are being progressively introduced together with regulations aimed at making an accountant's job easier. The systems available on the market vary from very simple ones built upon Excel spreadsheets, more advanced systems for small and medium sized enterprises developed by COMARCH-CDN (OPTIMA), Matrix.pl (Symfonia@) or InsERT (Rewior), to the most complex such as SAP, BAAN or IFS. As nowadays computers' hard drives are used for keeping, registering and evidencing financial record 1 , tax declarations may be transferred directly to appropriate tax offices without the need for an accountant to leave his or her desk, and import and export of documents can be easily monitored. The electronic systems allow easy and fast access to archival information, easy correction of implemented data and offer a big amount of reminders and tips on how to deal with mistakes in accounting documents.


A series of dimethylmethylene-bridged N-heterotriangulenes decorated with one, two, and three electron-withdrawing 4-pyridyls were synthesized. Their photophysical and electrochemical characteristics were examined and their successful application in n-type TiO2- and ZnO-based dye-sensitized solar cells demonstrated the ability of the 4-pyridyl moiety to act as an anchor.


OBJECTIVES:To assess the effect of acute changes in serotonin (5-HT) synthesis using the acute tryptophan depletion (ATD) paradigm on gastrointestinal (GI) and mood symptoms in irritable bowel syndrome (IBS).METHODS:In a randomized double-blind crossover study, 29 subjects (18 patients with ROME II defined IBS and 11 age-matched controls) were studied under ATD and acute tryptophan increase (ATI) conditions. GI symptoms, mood and anxiety ratings, as well as plasma tryptophan concentrations were measured.RESULTS:Total (and free) plasma tryptophan concentrations decreased on the ATD day in patients (73% [82%]) and controls (73% [80%]), and increased on the ATI day in patients (59% [143%]) and controls (61% [381%]). Compared with the ATD day, IBS patients reported more GI symptoms on the ATI day at +210 (p < 0.001) and at +270 (p < 0.05) min post drink. IBS patients also reported less anxiety on the ATI day compared with the ATD day at +270 min (p < 0.001). ATD and ATI did not affect these ratings in control participants. IBS patients had a lower mood compared with controls (p < 0.05), but this did not differ between the ATI and ATD days in either group.CONCLUSIONS:IBS patients' GI and anxiety responses to changes in tryptophan load differ from controls. This suggests a difference in serotonergic functioning between these two groups and provides evidence to support the hypothesis that 5-HT dysfunction is involved in IBS.


follows. 1. The cheek teeth, which were rootless and continued to grow as their occlusal surfaces were worn down, were compound teeth composing of three plates, mesial, distal and central plates. Each plate were covered with the enamel circumference of the dentin from occlusal to basal side, except only the lingual of them which was covered with the primary cement. There were stood between each plate the cartilage cement with which they were fixed strongly. 2. The periodontal membrane between the lingual cement and the alveolar bone showed structure similar to those of the rooted teeth. However, those between neighboring teeth showed characteristic construction to the present animals; on the surfaces of the enamel there were distributed at almost regular intervals the cement pearls, from which the bundles of Sharpey's fibers were radiated and intersected with those of the opposite side from the lamina propria mucosae of the gingiva to the tip


This study describe seasonal patterns in the variation of phytoplankton frequency in the water surface and basal layers and their spatial distributions at seven stations in Hwadang-ri, Goseng-gun in 2013. The phytoplankton community at Hwadang-ri was very diverse, with 60 taxa identified, representing three classes. Diatoms (Bacillariophyceae) exhibited the greatest diversity, with 41 taxa identified. These were followed by the dinoflagellates Dinophyceae, Cryptophyceae, and Eugenophyceae, with 16 taxa, two taxa, and one taxon, respectively. Water surfaces were shown with the relative individual density or abundance across areas. Except in January, Shannon?Weaver indices of diversity of the water surface layer were lower than those of the basal layer. In addition, evenness indices of the basal layer were higher than those of the water surface layer, except in January. For the community as a whole, the values of s-diversity were low for the seven stations: 1.125 for the water surface layer and 1.481 for the basal layer. Seasonal values for s-diversity were similar at the seven stations: 1.725 for the water surface layer and 1.347 for the basal layer. The phytoplankton community showed high taxonomic homogeneity in all four seasons, in addition to similar trends in seasonal development at depths in the same stations. However, the size distribution of the abundance and biomass showed a statistically significant west-east difference.


The aim of this study was to structure a knowledge matrix, through in which to manifest the features of blended learning , its concept , success criteria, advantages and its application in university teaching , many studies have agreed that blended learning is the natural evolution of E-learning . it is perceived as a teaching – learning method which blends modern techniques and traditional methods together in specific time and place frames, within normal environmental classroom teaching circumstances, in which the teacher and the student interact, each one according to his role and the requirements of the teaching situation, with the least possible cost in order to reach the teaching outcomes with high com pretence and quality. It appeared that the process of blending between different teaching methods does not occur in a random or moody way, but in an organized homogeneous scientific method , which is governed by several criteria and controls related to the requirements of the teaching situation . Therefore , the blended learning success criteria in its excellent aims , teachers and students good performance, excellent instructional content ,perfect infers and technical stature , provision of financial potentials societal mobilization. The obstacles which hinder the application of blended learning are centered around the high financial cost of the inputs of such kind of learning, the low level of education experience and skill of some teachers and students in dealing seriously with information and communication technology and teaching technology. The study concluded by emphasizing the importance of reconsidering the inputs of the instructional process and the procedures of its implementation in order to cope with the concept of electronic and technological revolution employ its basics to achieve the requirements of current stage , pursue novelty , persuade individuals that change and development are a modern necessity. Keywords : blended learning, electronic learning, university teaching, technological revolution


Mapping spaces of translation in twentieth-century Latin American print culture sets out with an ambitious task: to map the intersections of translation and print culture in contemporary America. from a transnational scope, charting and comparative methodological theoretical inquiry, case study she centrality of translation in print culture, a key condition in the formation of Latin American thought (2). this claim is a careful contextualization of translation as contested terrain inseparable from geopolitics.


THE INVENTION CONCERNS A DEVICE FOR DETECTION OF FLUID LEVEL IN A TANK. DEVICE INCLUDING CREW LEVEL DETECTOR IN TWO ARMS 10, 13 ARTICULATED ON A COMMON STAND STILL AROUND 33 FIRST LINES 11, 14 RESPECTIVE PARALLEL, HORIZONTAL GENERALLY, AND ORGAN SUPPORT MOBILE 17 CARRYING A FLOAT ADAPTED TO FOLLOW FLUID LEVEL, SUCH MEMBER SUPPORT 17 IS JOINT ON BOTH ARMS 10, 13 REMOTE FIRST LINES 11, 14 AROUND SECOND AXES 12, 15 RESPECTIVE GENERALLY PARALLEL TO FIRST, SO THAT WHEN MOVING FLUID LEVEL THE FLOAT follow CURVED TRACK SET BY THE ROTATION COMBINED ARMS, THE FLOAT COOPERATING WITH SENSITIVE BODY CAPABLE OF GENERATING A REPRESENTATIVE INFORMATION POSITION THAT FLOAT.


Using the Becker-Doring cluster equations as an example, we highlight some of the problems that can arise in the numerical approximation of dynamical systems with slowly varying solutions. We describe the Becker-Doring model, summarize some of its properties and construct a numerical approximation which allows accurate and efficient computation of solutions in the long, slowly varying metastable phase. We use the approximation to obtain test results and discuss the clear relationship between them and equilibrium solutions of the Becker-Doring equations.


What is the problem and what is known about it so far? Research studies have shown that physical fitness during adulthood helps to prevent type 2 diabetes mellitus (DM). No studies have examined whether poor physical fitness during late adolescence is a risk factor for type 2 DM later in life. Why did the researchers do this particular study? To understand how poor physical fitness (being out of shape) is related to the risk for type 2 DM during adulthood. Who was studied? Approximately 1.5 million Swedish male military recruits aged 18 years from 1969 to 1997 who did not have type 2 DM. How was the study done? All of the military recruits were required to have a standardized examination of physical fitness at age 18 years that included an assessment of aerobic capacity (or the maximum energy used during exercise) and muscle strength. Investigators then examined medical records until 31 December 2012 to see whether any of the military recruits were diagnosed with type 2 DM after the fitness examination. What did the researchers find? During the study, 34,008 men were diagnosed with type 2 DM. Men with low aerobic capacity at the start of the study had an increased risk for DM regardless of muscle strength levels. The combination of low aerobic capacity and muscle strength levels was associated with the highest risk for type 2 DM. What were the limitations of the study? No women were included in the study, and investigators did not have information on measurements of physical fitness during follow-up. What are the implications of the study? This study of male military recruits showed an association between physical fitness during late adolescence and an increased risk for type 2 DM during adulthood. Patients should continue to follow a healthy lifestyle that includes regular physical activity.


Design and application of unmanned aerial vehicle include many aspects of high technology,and it is a highly complex electro-mechanical system.To ensure the reliability of flight,it is an essential work to perform fault detection.A data mining technology based on FRDB is proposed to study fault analysis to unmanned aerial vehicle,and also the corresponding algorithm is designed.Selection and projection operation from FRDB are used to separate the super-bad fields of the relevant part and form the corresponding data files to establish the basis of statistical analysis.Besides,statistic analysis is performed to the distribution of the fault.In testing procedure,the components of the unmanned aerial vehicle control system are paid high attention.In order to achieve the automation and semi-automation of statistical analysis,normalized treatment to the testing data and the database building must be paid attention.


AHSTRACT: Casein was hydrolyzed by trapsin to 5% degree of hydrolysis, and the hydrolysare was fractionated by ultrafiltration. While sereening for the best emulsifying properties, the retentate fraction was systematically fractionated by ammonium sulfate precipitation, ion exchange, and reverse-phase high-performance liquid chromatography (HPLC). Residue from 30% ammonium sulfate saturation yielded 3 fractions on anion exchange chromatography. Preparative reverse-phase HPLC was used to isolate 4 peptides with good emulsilying properties for characterization. Computational methods were used to complement amino acid sequencing, and the peptides were identified as origioating from α casein (f167-208), β-casein (f48-63), and (f129-84), A 4th peptide couid not be conclusively identified. Properties of the emulsifying peptides are discussed.


Well, someone can decide by themselves what they want to do and need to do but sometimes, that kind of person will need some algorithmic learning theory 16th international conference alt 2005 singapore october 8 11 2005 references. People with open minded will always try to seek for the new things and information from many sources. On the contrary, people with closed mind will always think that they can do it by their principals. So, what kind of person are you?


Using I DEAS designers can accomplish the functions of the butterfly valve products.Through these functions, we can improve the designs,raise economics efficiency .


Plant phenolic and carotenoid compounds are known for their beneficial effects on human health, and they are present in a great variety of fruits and vegetables. The profile of bioactive compounds in papaya fruit has not been completely elucidated and research has been focused on characterization of mature fruit flesh composition and proteolitic enzymes with industrial applications. The objective of this work was to identify potential bioactive compounds previously related to health improvement, in papaya peel and flesh tissues during storage at 25°C. Samples of peel and flesh tissue of C. papaya fruits were submitted to solvent extraction and hydrolysis in order to identify free and conjugated phenolics by liquid chromatography/diode array detector coupled to electro spray ionization mass spectrometry (LC/DAD-MS-ESI). Caffeic acid, protocatechuic acid-hexoside, sinapic acid, quercetin-3-O-rutinoside, ferulic acid, myricetin, quercetin, isorhamnetin, kaempferol, caffeoylhexose-deoxyhexose, caffeoylhexoside and gallic acid-deoxyhexoside phenolics were found in peel extracts while caffeic acid, protocatechuic acid and gallic acid hexosides were present in the flesh. Carotenoids were identified in the flesh by LC/DAD coupled to atmospheric pressure ionization mass spectrometry (LC/DAD-MS-APCI). Lycopene, β-criptoxhantin and β-carotene were the most abundant carotenoids in that order. No significant differences were observed in phenolic profile during storage; however, lycopene and β-criptoxhantin levels tend to increase in storage. Identified phenolic and carotenoid compounds have proved to act as potent antioxidants in biological systems, and some are presumed to act as preventative anticarcinogens agents in vitro and in vivo. The presence of these compounds could explain the health benefits attributed to this fruit, and opens future studies towards mode of action elucidation in biological systems.


In this work, predictions of the Ginzburg–Landau theory of dark energy (GLT) for cosmic microwave background (CMB) lensing are studied. We find that the time and scale dependence of the dark energy fluctuations in this semiphenomenological model is favored by data in several ways. First, unlike ΛCDM, ℓ ≤ 801 and ℓ > 801 ranges of the CMB angular power spectrum are consistent in this framework. Second, the lensing amplitude A L is completely consistent with unity when GLT is confronted with CMB data, even without including CMB lensing data. Therefore the lensing anomaly is absent in this model. Although the background evolution of dark energy in this model is able to reconcile the H 0 inferred from CMB with that directly measured through observing nearby standard candles, the inclusion of Baryon Acoustic Oscillations (BAO) data brings the inferred H 0 close to what ΛCDM predicts and hence the Hubble tension is not fully eased. However, this does not affect the posterior on A L and the lensing anomaly is still absent.


The purpose of this study was to examine the creative behavior characteristics of 4-5 year olds and to investigate the relationship between these characteristics and the mothers' supportive child-rearing behaviors. The subjects were 125 pairs of young children and their mothers in Seoul and Gyeonggi-do. The major results of this study were as follows. First, young children were rated to show uniqueness, openness, sensitivity, playfulness, and perseverance as creative behavior characteristics by their teacher. There were no significant differences between creative behavior characteristics of boys and girls. Second, the more mother used supportive child-rearing behaviors, the higher their children's creative behavior characteristics were estimated.


Because of the speciality of viscous oil producing method and very complex geological conditions in Liaohe oil region, special well completion techniques are needed. Thus a study is performed on the completion method for viscous oil production in Liaohe Oilfield, the fundamental principles of perforation, completion, sand control completion and completion of external pipe plugging and their advantages, shortcomings and the application tools are discussed.


Voyager I1 observations of Triton revealed it to be a geologically active satellite with at least two erupting plumes, numerous plume deposits, and a polar cap that is predicted to wax and wane in a seasonal cycle. A long term record of seasonal change, and possibly geologic activity, on Triton is provided by telescopic observations of Triton's albedo, rotational lightcurve, and color through time (Buratti et al., 1994). Changes in the amplitude of Triton's lightcurve since the Voyager encounter in 1989 suggest sustained activity on it within the past decade (Cobb et al., 2001).


lutions can be uniformly applied with the FFT system over the full range of process speeds studied (1.54 to 12.23 m/s), at very low co-applied water levels (6.4 to 7.7%), which effectively eliminate the need for a fabric drying step. The full utilization of this capability in a continuous resin application/fabric curing process depends on the optimal time/temperature sequence of the curing stage.


Analysis of qualitative data reveals that the formal and informal peer networks of African American students in predominantly White elite independent schools support these students' academic success, create opportunities for them to reaffirm their racial identities, and facilitate their adjustment to settings that are otherwise difficult for Blacks toit into. Contrasted to research showing that adopting academically successful behaviors leads Black students to being labeled as "acting White," the sampled students made social gains within school when they were academically successful. However, this success did not result in full acceptance by African American peers outside the school. The authors conclude that the dynamics and ideologies of African American peer groups are more complex than prior research has suggested. INTRODUCTION A plethora of research documents the educational experiences of African American students. Early research in this area primarily focused on the failures of African American students to achieve at the same academic level as their White counterparts (Coleman et al., 1969; Jencks et al., 1972). More recently, the emphasis in research has shifted from studies of academic failure to studies of the factors that contribute to African American student success (Ladson-Billings, 1990; Lee, Winfield, & Wilson, 1991). Since the 1960s, increasing numbers of African American students have been enrolling in predominantly White elite independent schools known to prepare students for positions of power and leadership (Cookson & Persell, 1985). Much of the increase in enrollment can be attributed to the efforts of a number of organizations, including A Better Chance (ABC), Prep for Prep, Black Student Fund (BSF), and the Baltimore Educational Scholarship Trust (BEST), that have initiated and maintained the presence and participation of African American students in these schools (Cookson & Persell, 1991; Johnson & Anderson,1992). Additionally, the majority of these schools have enacted policies of nondiscrimination, and a growing number actively recruit minority students in their efforts to create more diverse student bodies on their campuses (Speede-Franklin, 1988). Despite these efforts, research shows that predominantly White elite independent schools, with their history of racial exclusion, are often places where African American students find it difficult to fit in (Brookins, 1988; Zweigenhaft & Domhoff, 1991). Moreover, African American students in such institutions have frequently reported that they feel caught between two cultures and consequently doubly marginalized.' They have also indicated that often they feel alienated from the culture of the school and from their own parents and friends, particularly in boarding school environments (Cookson & Persell, 1991). This is not surprising, as NELS:88 data indicate that African American students at predominantly White elite independent schools have substantially fewer family economic resources relative to the school populations as a whole (Schneider & Shouse, 1992). Research also suggests that African American students at these institutions may have weaker social relationships with their teachers than do their peers at the schools, and that this lack of connection may affect their motivation and academic performance (Schneider & Shouse, 1992). Given these findings, it appears that the social bonds that African American students at predominantly White elite independent schools develop with each other may provide an important but as yet unexplored support network that could potentially contribute to their academic performance and sense of identity and belonging. Although African American students in such settings often form their own cliques and clubs (Cookson & Persell, 1991), the functions served by these peer networks are not clearly understood. Thus, the study presented here used qualitative interview data to explore the peer networks developed by African American students enrolled in predominantly White elite independent schools through the Baltimore Educational Scholarship Trust (BEST). …


The phylogeny of subtribe Gorteriinae (Asteraceae‐Arctotideae) is investigated by means of cladistic analysis of morphological characters. Two sister groups are formed, namely a Gorteria clade also containing Hirpicium and Gazania, and a Berkheya clade, which also contains Cullumia, Cuspidia, Didelta and Heterorhachis. The Gorteria clade has strong jackknife support and is diagnosed by four morphological characters (leaves with longitudinally striate hairs, fringed anther apical appendages, pollen of the "Gazania‐type", and subulate‐ensiform, ascending style sweeping hairs) that are unique within the Asteraceae. The Berkheya clade is moderately supported and diagnosed by two characters without contradiction (spiny leaves, and mamillate, large style sweeping hairs). Hirpicium and Berkheya are paraphyletic, with the other, morphologically more homogeneous genera (Gorteria, and Gazania, Cullumia, Cuspidia, Didelta and Heterorhachis, respectively) nested within them. There is some evidence for a radiation of species of the summer rainfall area of South Africa and tropical Africa and the corresponding species are nested within a grade confined to the Cape Floristic Region.


As is well known, a single stable controller which stabilizes n SISO plants (strong simultaneous stabilization) is equivalent to a single controller (not necessarily stable) which stabilizes n+1 plants (simultaneous stabilization). Strong simultaneous stabilization and simultaneous stabilization are two open problems that need to be solved urgently in linear systems. Under the assumption that all the plants have the same simple unstable zeros, this paper gives a sufficient condition for strong simultaneous stabilization. Under this condition, in order to insure n SISO plants to be strong simultaneous stabilization, it is only necessary to determine the unstable zeros of n plants, and to determine whether the corresponding matrix determined by the unstable zeros is positive definite. This paper also gives an algorithm to determine the simultaneous stabilization controller, and thus enriches the condition and algorithm for the strong simultaneous stabilization.


NGA GMPEs (NGA-West1, 2008 and NGA-West2, 2014) are beginning to be widely used in seismic hazard analyses. However, these new models are considerably more complicated than previous GMPEs, and they require several more input parameters. Users are faced with the challenge of estimating unknown input parameters when implementing NGA models. In this paper, we are interested in fault-to-site distances parameter. Scherbaum et al. (2004) (termed "SSC04") ever developed empirical expressions for converting source-to-site distance measures using simulated source geometries. The conversion equations are in the form of polynomial functions of M, RJB, and style of faulting. Kaklamanos et al. (2011) (termed "KBB11") derived physical equations relating the three distance measures (RJB, RRUP, and RX) found in the NGA 2008 models using various geometric principles. KBB11 used the Joyner-Boore distance (RJB) as the primary distance measure to compute other distances (RRUP, RX) by characterizing the earthquake source by the geometric parameters down-dip rupture width (W), depth-to-top of rupture (ZTOR), fault dip (), and source-to-site azimuth (alpha). When RX is also needed (as in the AS08 and CY08 models), KBB11 method is advantageous, because RX cannot be estimated using the SSC04 relationships (because RX had not yet been introduced as a distance measure in 2004). One other potential issue is that the SSC04 equations are technically only applicable for RJB<100 km, whereas KBB2011 equations are physically derived and are applicable for any distance range at which the flat-earth assumption is valid (typically, several hundred kilometers). KBB11 used the Joyner-Boore distance (RJB) as the primary distance measure to compute other distances (RRUP, RX). But in one situation RJB is equal to zero, which means the site is located directly above the ruptured area; either RX or RRUP must be specified in order to calculate the third distance parameter using KBB11. In some other situations, when the fault trace and site location is known, we need to simulate the ground motion caused by different segment rupture of the whole entire fault. In these cases, the RX and RXY are easily measured by GIS tools but the RJB is dependent on the down-dip rupture width (W). In this paper we introduce a new distance measure RXY (the closest distance from top of rupture) which is used to estimate source-to-site azimuth alpha (sin(alpha)= RX/ RXY) and RY (RY= RXY·cos()). Based on KBB11 we derived distance equations using the RX and RXY to compute RJB, RRUP, RX, and RY0.


Highly symmetric [Pd3]+ clusters that present delocalized metal-metal bonds can catalyse the selective semi-reduction of internal alkynes to cis-alkenes. Studies on factors governing the formation of all-metal aromatics enabled the design of an optimised catalytic system that delivers cis-alkenes with almost complete selectivity on a gram scale with very low catalyst loadings (0.03 mol%).


Metal‐catalyzed trans‐1,2‐hydrosilylations and hydroborations of terminal alkynes that generate synthetically valuable (Z)‐alkenylsilanes and (Z)‐alkenylboranes remain challenging due to the (E)‐selective nature of the reactions and the formation of the thermodynamically unfavorable (Z)‐isomer. The development of new, efficient catalytic systems for the (Z)‐selective hydrosilylation and hydroboration of terminal alkynes is thus highly desirable from a fundamental perspective as it would deepen our understanding of the metal‐catalyzed (Z)‐selective hydrosilylation and hydroboration of terminal alkynes. This personal account describes our research for developing a ruthenium complex that can efficiently catalyze the hydrosilylation and hydroboration of terminal alkynes, and for exploring the factors controlling (Z)‐selectivity of the reactions. Our effort into the activation of B‐protected boronic acids, R−B(dan) (dan=naphthalene‐1,8‐diaminato), that was believed not to participate in Suzuki‐Miyaura cross‐coupling, is also discussed.


The ultra-high pressure sterilization is a novel method for food processing and has a promising future in food industry. Several influencial parameters in the sterilization with this method, including processing pressure, sustaining time and pH value, are studied using Escherichia coli and Bacillus subtilis, which commonly exist in foods, as the objects of the experiments. The results indicate that the reductions of microorganisms increase with an increase of processing pressure and sustaining time. While the effects of high-pressure and sustaining time on Microorganisms vary gently after they reach a certain value. A acidic medium or alkaline medium are helpful for high pressure sterilization, and the neutral circumstance is the last choice for it. We also have studied the activity of Bacteria after high-pressure sterilization. The results show that the activity of Escherichia coli reduces after high-pressure treatment. The study provides some valuable references to optimize of high-pressure sterilization process.


A two-phase study was conducted to assess the suitability of passive monitoring for the collection of airborne vapor degreasing solvents under laboratory and field conditions. The laboratory stage of the investigation involved the determination of collection efficiencies for methyl chloroform (MC) and trichloroethylene (TCE). A 6920 L static chamber was used to establish standard atmospheres of these solvents at various concentrations, which were then sampled using passive monitors; samples were subsequently analyzed by gas-liquid chromatography. In the second part of the investigation, several MC and TCE vapor degreaser operations were monitored at US Army industrial plants. The purpose of the field study was to develop worker exposure prof iles and to obtain a side-by-side comparison of the passive monitor with the traditional charcoal tube sampler. Presented are statistically reduced data and the performance characteristics of both collection techniques.


Today Voice over Internet Protocol (VoIP) is used in large scale to deliver voice and multimedia over the packet data networks, such as the Internet. The Session Initiation Protocol (SIP) is widely used as a signalling protocol for VoIP. As SIP is being used more, the security of it is an important issue. In this paper, we concentrate on user authentication in SIP. We examine current solutions in authentication and analyse them. As a result, some security issues and problems were found, which expose the SIP authentication to different kind of threats.


Stromal Cells in Response to rhBMP2 Goyal, R; James, AW; Zara, JN; Chiang, M; Yuan, W; Askarinam, A; Pang, S; Corselli, M; Stoker, D; Zhang, X; Peault, B; Ting, K; +Soo, C Dental and Craniofacial Research Institute and Section of Orthodontics, School of Dentistry, UCLA, +UCLA and Orthopaedic Hospital Department of Orthopaedic Surgery, and the Orthopaedic Hospital Research Center, University of California, Los Angeles, Los Angeles, CA 90095, Private practice, Marina del Rey, CA, Division of Plastic and Reconstructive Surgery, University of Southern California, Center for Cardiovascular Science, Edinburgh, UK email@example.com INTRODUCTION: Bone regeneration is a complex process that entails recruitment, proliferation and differentiation of osteoprogenitor cells into osteoblasts. Autologous bone grafts are the standard of care for bone repair. However, the supply is limited and the donor-site morbidity of autograft can be as high as 25 percent. The aim of this study is to search for effective alternative sources of stromal cells for bone tissue engineering. An ideal stem cell source for such engineering efforts is one that is safe, abundant, harvested by minimally invasive procedures, and rapidly processed or isolated. Adipose tissue has been identified to satisfy these criteria. However, the human stromal vascular fraction (hSVF) of adipose tissue is a heterogeneous cell population consisting of dead cells, non-stem cells, variable potency cells and endothelial cells that are known to inhibit osteogenic differentiation. In comparison, human perivascular stem cells (hPSCs), isolated through FACS (fluorescence activated cell sorting) and without the need for cell culture, closely resemble culture-derived mesenchymal stem cells (MSCs) and are a more highly purified cell population that may be more effective than hSVF in regenerating bone. Human PSCs can theoretically be used in a one-step operation for harvest and subsequent bone application into the same patient– representing a potential breakthrough for skeletal regenerative medicine. Combining such a homogeneous osteogenic cell source with a potent osteoinductive growth factor is logical for improved skeletal engineering. In this study, we examined the osteogenic potential of hPSCs versus that of patient-matched hSVF, when combined with rhBMP2 (recombinant bone morphogenetic protein2). rhBMP2 although a potent stimulator of osteogenesis, also stimulates pleiotropic effects including adipogenesis, and an increase in cystic bone formation. The comparative ability of rhBMP2 to induce osteogenic differentiation in freshly derived and non-cultured populations of adipose-derived hPSCs and hSVF has not yet been described. Using a SCID mouse muscle pouch model, we hypothesize that homogenously purified hPSCs will form bone more effectively than hSVF from the same donor, in combination with the osteoinductive growth factor rhBMP2.


Let H be a HILBERT space, let C(H) denote the set of all closed densely defined linear operators on H and let 𝔏(H) denote the set of all bounded elements of C(H). If A, B𝔏(H), set: A ∼ B iff A — B is compact. Then ∼ is an equivalence relation on 𝔏(H) and many results have been stated and proved making use of this equivalence relation (e.g. correction of spectra by compact perturbations, CALKIN algebras … etc …). The aim of the present paper is to show that it is possible to extend ∼ to the whole of CH) in such a way that (after suitable modifications) most of the results referred to above on 𝔏(H) are still true on C(H).


Conformal Prediction (CP) allows to perform rigorous uncertainty quantification by constructing a prediction set $C(X)$ satisfying $\mathbb{P}(Y \in C(X))\geq 1-\alpha$ for a user-chosen $\alpha \in [0,1]$ by relying on calibration data $(X_1,Y_1),...,(X_n,Y_n)$ from $\mathbb{P}=\mathbb{P}^{X} \otimes \mathbb{P}^{Y|X}$. It is typically implicitly assumed that $\mathbb{P}^{Y|X}$ is the"true"posterior label distribution. However, in many real-world scenarios, the labels $Y_1,...,Y_n$ are obtained by aggregating expert opinions using a voting procedure, resulting in a one-hot distribution $\mathbb{P}_{vote}^{Y|X}$. For such ``voted'' labels, CP guarantees are thus w.r.t. $\mathbb{P}_{vote}=\mathbb{P}^X \otimes \mathbb{P}_{vote}^{Y|X}$ rather than the true distribution $\mathbb{P}$. In cases with unambiguous ground truth labels, the distinction between $\mathbb{P}_{vote}$ and $\mathbb{P}$ is irrelevant. However, when experts do not agree because of ambiguous labels, approximating $\mathbb{P}^{Y|X}$ with a one-hot distribution $\mathbb{P}_{vote}^{Y|X}$ ignores this uncertainty. In this paper, we propose to leverage expert opinions to approximate $\mathbb{P}^{Y|X}$ using a non-degenerate distribution $\mathbb{P}_{agg}^{Y|X}$. We develop Monte Carlo CP procedures which provide guarantees w.r.t. $\mathbb{P}_{agg}=\mathbb{P}^X \otimes \mathbb{P}_{agg}^{Y|X}$ by sampling multiple synthetic pseudo-labels from $\mathbb{P}_{agg}^{Y|X}$ for each calibration example $X_1,...,X_n$. In a case study of skin condition classification with significant disagreement among expert annotators, we show that applying CP w.r.t. $\mathbb{P}_{vote}$ under-covers expert annotations: calibrated for $72\%$ coverage, it falls short by on average $10\%$; our Monte Carlo CP closes this gap both empirically and theoretically.


This paper studies the frost resistance, retraction performance, flexure resistance elastic modulus of concrete mixed and not mixed (LH-B) by tests and compares the performance of pavements containing varied cement weight of the two kinds.


Purpose
The purpose of this paper is to examine the potential non-linear relationship between family ownership as a governance mechanism and exchange rate exposure of firms that use financial hedging.

Design/methodology/approach
The exchange rate exposure is estimated using two-factor Jorion (1990) model for a sample of 312 Indian firms over the period from 2001 to 2016. The cross-sectional regression model is used at the second stage to investigate the effects of family ownership on exposure for the firms that use currency derivatives.

Findings
The results suggest a significant non-linear cubic relationship between family ownership and exchange rate exposure. Exchange rate exposure increases with family ownership at low and high levels (as a result of improper hedging) and decreases with family ownership at intermediate levels (as a consequence of value-enhancing hedging).

Practical implications
The study has practical significance for firms to understand the circumstances in which currency derivatives usage is ineffective in alleviating exposure. Firms that have high or low family ownership should integrate operational hedges with financial hedges and should incorporate other firm-level governance mechanisms to avoid the misuse of derivatives.

Originality/value
This study provides new evidence that the relationship between family ownership and exchange rate exposure is non-linear for firms that use financial hedging which has not been investigated before in the prior literature.


The Degree of Geology and Mines of the Technical University of Loja boost this Survey
Geological-Structural and inventory of landslides Area three (3) of the basin of Loja, in
an area of 2900 hectares, in order to have information updated and define in a better way the
contacts of different geological formations and their structural and tectonic elements that help
define the geological and tectonic structure of the entire sedimentary basin of Loja.

The investigation began with the description of the project, comprising; geographical location,
accessibility, climate and hydrography, then the geological field research was developed,
with the description of geological outcrops and structural data, and proceeded to perform the
geological survey of the area. Finally the interpretation of results was performed to define the
geological units present, contacts, lithology, structure and correlated with the regional
geological map of Hungerbuhler et al.,2002. The landslide inventory was also conducted to
define their conditioning and triggering factors.


This paper covers the general performance capability and limitations of the various types of mechanical shaft seals in use today in refrigeration compressors and describes the benefits gained by the change to edge welded metal bellows seals. Additionally, new developments and enhancements to these seals including techniques for future environmental control are outlined.


In this letter, we propose an iterative algorithm for the joint estimation of the channel covariance matrices and the channel vector for the spatially-correlated massive MIMO system with the following main advantages: low pilot overhead, improved mean square error (MSE), and low complexity. The results show that this scheme outperforms the conventional estimation schemes in terms of the required pilot overhead and the resulting MSE. The results also show that the achievable sum rate of the proposed scheme tends to that of the ideal case that the channel covariance matrices are assumed to be perfectly known at the base station.


The role of local excision as an alternative to radical resection for the treatment of certain rectal cancers remains controversial, mainly due to problems con®rming the appropriateness of each tumour. There is a general consensus that lesions need to be small (<3 cm), extraperitoneal, T1 on transrectal ultrasonography and polypoid rather than ulcerated. There is also some evidence to support limitation of this procedure to only well or moderately differentiated lesions. Nevertheless, even when these criteria are ful®lled, between 13% and 20% of tumours will be associated with occult lymph node invasion outside the ®eld of resection. In view of this. local resection is on the whole only advocated for small mobile T1 lesions or in patients with localized rectal cancer with or without metastases who are un®t for more radical surgery or where the only alternative is an abdominoperineal resection. Budhoo & Hancock report a series of 22 patients who underwent local treatment for early rectal cancer, all for curative intent. Three patients were considered un®t for major resection and the remainder were treated in this manner due to patient preference or surgical selection. All patients were clinically assessed, only prior to local resection, without the bene®t of transrectal ultrasound. Ten were subsequently shown to have T1 lesions and 12 were T2. The overall recurrence rate was 27%, all of which were extraluminal. All recurrences occurred in T2 lesions which were on the whole large with a tendency to moderate to poor differentiation. Half of the local recurrences were salvaged by radical surgery. The authors suggest that on clinical assessment alone selection of cases can be appropriate and that salvage surgery, when recurrence is detected, is possible. The authors emphasize that careful follow up over a long period is required to avoid late recurrence. Transanal endoscopic microsurgery (TEMS), introduced in 1993 by Buess and colleagues, was developed in view of the invasiveness of the posterior approach to the rectum from local resection and the limited view given by conventional transanal approach. Although the technique is complex and requires substantial training, it is possible to remove tumours up to 20 cm posteriorly and 12 cm anteriorly. Nevertheless, the most important complication remains local recurrence, with Buess reporting a rate of 6% for T1 lesions over a limited follow-up period, whilst Steel reported a recurrence rate of 15.5% for T2 lesions. Limited data from the USA however has suggested that good results may be obtained in conjunction with chemoradiotherapy for T2 lesions. The reported salvage rate for local recurrence using this technique ranges from 25% to 50%. The results of subsequent treatment of recurrence remains one of the most important issues in local treatment for early rectal cancer, as if it could be effectively dealt with then its development could be regarded as a temporary inconvenience rather than an oncological disaster. At present only 3±10% of rectal tumours are suitable for local resection. However, in light of the ®gures outlined above, with the exception of those who are deemed medically un®t for a major procedure, all such patients should be treated in the setting of a prospective audit or clinical trial.


The recent marketing literature reflects a growing interest in relationship management issues. In particular, several recent studies have drawn on transaction cost and agency theory to examine how interfirm relationships are organized. The general premise is that explicit control mechanisms must be deployed in a relationship to manage a partner's potential opportunism. Although previous research has shown that different mechanisms can be used, the tendency has been to examine individual mechanisms in isolation. The authors develop hypotheses about interdependences between different control mechanisms. They also identify some of the contextual factors that influence their use. The framework is tested empirically by examining how chemical manufacturers organize their supplier relationships. The results generally support the hypothesis that firms' choices among control mechanisms are influenced by contextual factors. Only limited support is found for the hypothesis that interdependencies exist between different mechanisms.


This paper analyzed the cause of explode in working face with groundpressure,gases explode,spontancous combustion,or firepressure theory and exprounded detailed the explode process.It gave three new standpoints about mechanism of explode in working face as follow: (1)The coal combustion is lead to explode by only fire souce; (2) The coal stacking combustion positive feedback is the main reason to lead to the coal combustion; (3)The firepresure is power souce formed explode condition.It will provide scientific theoretical basis for preventing explode in waste in the future.


The Centre of Intercultural Documentation and the Institute for Contemporary Latin Studies are located in the city of Cuernavaca in Mexico. The main emphasis of the Institute is to work with Latin Americans in leadership training courses. Summer courses are also held, attended both by Latin Americans and by students from USA and other countries — mostly Roman Catholics — intending to work as missionaries in Latin American countries.

The Institute describes itself as offering "an unusual approach to the understanding of modern man in Latin America, as he experiences the recent and rapid change of all institutions around him". The Institute accepts as students "both those whose main field of study or research is Latin America and those who seek a new dimension in their understanding of North American social change as contrasted with change in capital-starved areas of the world". (Editor's note.)


Study Design: Prospective study. Aims and objectives: To study the efficacy, advantages, and associated complications of Endoscopic Destandau method in comparison with standard open discectomies in lumbar disc herniations at a semi urban setup. Materials and methods: A total of 42 patients were enrolled in the study. All the details pertaining to the history, clinical examination, surgical procedure and postoperative recovery were noted. 19 patients underwent discectomy by Endoscopic discectomy by Destandau method (EDM) and 23 patients underwent standard open discectomy (SOD). Patients were followed up for a minimum of 12 months prospectively. Visual analogue score (VAS) was noted preoperatively, immediate postop (48hrs postsurgery) and at follow up. Outcome is measured at 12 months follow up. Results: 47.6% patients were in the age group of 31-40 years, most common site to be involved in disc prolapse was L4-L5 in 54.75%. The mean operative time was 82 min and the mean hospital stay was 2.8 days in EDM group compared to 126 mins and 8.5 days of SOD group. Average blood loss is 30 ml in EDM group and 180 ml in SOD group. The outcome was excellent good fair and poor in 47.82%, 43.47%, 4.3% and 4.3% respectively in SOD group compared to 68.4%, 21%, 5.3% and 5.3% in EDM group. Conclusions: EDM is novel, safe and effective technique that minimizes invasiveness of surgical approach for lumbar discectomy. The technique also offers decreased blood loss, shorter operative time, shorter in-hospital stay, less immediate postoperative pain, better cosmoses and early recovery to work.


A program was undertaken to identify an acceptable alternative to Dapon 35, an o-diallyl phthalate (DAP) prepolymer no longer available. Three o-DAP prepolymers from the Osaka Soda Company and four laboratory-scale prepolymers from Bendix-Kansas city were characterized and evaluated in DAP-fiberglass molding compounds. Gel permeation chromatography results for the Osaka prepolymers showed all three to be very close to one another in molecular weights (mw) and mw distributions, but slightly lower in both than Dapon 35. They are also slightly higher in monomer content. All three processed readily into DAP-fiberglass molding compounds and passed required physical property tests. One Osaka prepolymer was compounded into both asbestos and Orlon-DAP compounds on a production scale. Both compounds have passed all certification tests. The Bendix prepolymers were deliberately varied in mw and mw distribution and higher in monomer content than Dapon 35. Processing difficulties were encountered with both the lowest and highest molecular weight compounds, and the lowest molecular weight compound failed a number of physical property tests. The two intermediate molecular weight compounds processed readily and passed property tests. Guidelines were established for acceptable o-DAP prepolymers: (1) weight average mw (relative to polystyrene standards): 30,000 to 150,000; (2) mw distribution: 3.0 tomore » less than or equal to 18.0; and (3) DAP monomer content: 1.0 to less than or equal to 6.0%. 5 figures, 6 tables.« less


1. Assistant Prof, Dept of Paeadiatrics, NMCH, Noakhali 2. Associate Prof, Dept of Physiology, NMCH, Noakhali 3. RS, Surgery, NMCH, Noakhali 4. Assistant Prof, Dept of Pathology, BSMMU, Dhaka Address of Correspondence: Dr. Lutfan Nessa, Assistant Prof. Paed, NMC, Mob:01718174751, E-mail: lutfan.nessa@ yahoo.com Introduction Epidermolysis bullosa (EB) is a heterogenous group of diseases of the skin and mucous membranes which share the common feature of the formation of blisters and erosions in response to minor mechanical trauma. These disorders often have been referred to as mechanobullous diseases. Diagnosis is based on clinical symptomatology, histopathology, electron microscopy and genetic studies.1However in a resource limited setting, the diagnosis is mainly clinical. Age of onset, symptomatology and prognosis of various subtypes are varied.2Most cases of EB are inherited.3,4 A comprehensive classification based on clinical presentation, genetic pattern of inheritance and electron microscopic features was proposed in 1991 by the subcommittee of the National EB Registry.5 EB is classified into major 3 groups by the level at which separation occurs: EB simplex (EBS), is characterized by intraepidermal blistering, is usually inherited in an autosomal dominant manner with complete penetrance. Junctional EB (JEB), an autosomal recessive disease, demonstrate cleavage within the lamina lucida. Dystrophic EB (DEB) is characterized by separation of the sublamina densa and may be inherited as an autosomal dominant or recessive disease. The incidence of EB estimated by a National EB Registry report is 50 EB cases per 1 million of live births; of these cases, approximately 92% are EBS, 5% DEB, 1% JEB and 2% unclassified.3We describe a patient with JEB (which has an incidence of 1%) who was managed accordingly.


The invention discloses a vehicle-mounted physical parameter tester of geological heat of a ground source heat pump. The physical parameter tester comprises a heat-insulating water tank, an electrical heating tube, a circulating pump for a buried tube, a circulating pump for an evaporator, an air-cooled heat pump unit consisting of the evaporator, a compressor, a condenser, an expansion valve and a fan, and a controller. In the vehicle-mounted physical parameter tester of the geological heat of the ground source heat pump, the cold and heat source is provided by the air-cooled heat pump unit, so the whole tester has a compact structure, can be placed on a vehicle, and is very flexible and convenient to use. In addition, the cold and heat source mainly comes from air, so that other cooling and heating facilities are not needed. During testing, only a group of heat exchangers for the buried tube are needed to be buried, so that the testing cost can be greatly reduced. As the tester can be used for cooling (preparing cold water) and heating (preparing hot water), only one tester can meet the testing requirements of a thermal response method and a simulation method. Therefore, the tester is dual-purpose, and has a wide application range. In addition, the tester has high automation degree.


Eclipta alba (L.) Hassk has important role in the traditional systems of herbal medicine. Its free radical scavenging and antioxidant activity has been reported due to the presence of phenolic and flavonoids compounds. Endosulfan is a chlorinated hydrocarbon pesticide widely used in the field of agriculture and reported to have toxicity to liver, kidneys and blood chemistry of non target organisms including humans. The present study aims to assess the potential of medicinal plant E. alba to counter pesticide endosulfan induced biochemical and haematological alterations in Swiss albino mice. The biochemical analysis showed that serum levels of SGPT, ALP, total protein, albumin, urea, creatinine, total cholesterol and triglycerides, statistically significant increase (P < 0.01) in the endosulfan treated groups (groups-II and III) as compared to the control group (group-I). The RBC count and Hb concentrations showed a statistically very significant decrease (P<0.01) in mice that were orally administered Endosulfan (3 mg/Kg) for two weeks (group-II) and four weeks (group-III). The values of HCT, MCV, MCH and MCHC decreased and were statistically significant (P<0.05) as compared to the control group (group- I). Statistically a very significant (P<0.01) increase in the white blood corpuscles (WBC) count was observed in group-II and group-III. Where Endosulfan treated mice which were post-treated with aqueous leaf extract of E. alba (group-IV) showed recovery as indicated by the values of biochemical and hematological indices. The results indicate the potential of the aqueous leaf extract of E. alba as a therapeutic agent which may be used against Endosulfan induced hematological and biochemical alterations in swiss albino mice.


ABSTRACT The Alt-Right, a loose coalition of far-right groups which are particularly active online, claims that European integration is a part of a master plan by cosmopolitan elites to encourage globalisation and 'corporate capitalism' in order to partly replace and 'blend' the predominantly white population with migrants from outside Europe. Many Alt-Right followers argue that this conspiracy for a 'white genocide' can be traced back to Coudenhove-Kalergi's plan for a Paneuropean Union. Although this Alt-Right counternarrative to European integration is only believed in its entirety by a small group of people, who do not care that their historical claims are evidently false, bits and pieces of the narrative filter down to mainstream political actors. By employing narrative analysis and drawing on new research on online news websites and social media forums, this article will examine the Alt-Right's narrative entrepreneurs and their narratives.


This paper presents the calibration of three universal ductile fracture criteria with the stress triaxiality and the normalized third invariant of deviatoric stress dependence. Xue-Wierzbicki, Bai-Wierzbicki and Extended Mohr-Coulomb criteria are calibrated using butterfly specimen and newly designed notched tube specimen for an austenitic stainless steel. Different stress states necessary for successful calibration are generated by suitable combination of tension/compression-shear or tension/compression-torsion loading of both specimens, respectively. Suitability of the specimens for ductile fracture criteria calibration is evaluated comparing the range of reached stress states, the homogeneity of stress in process zone and appropriateness for the computational simulation of tests. Possible combination of above mentioned results with tensile testing of standard and notched cylindrical specimens is discussed, too.


The aim of the study is to determine the features of formation and use of feminitives denoting a profession or position in new media. The paper compares the feminitives often used in new media and the means of their formation with the units of the official naming of positions and professions of women in the legal field recorded in a classifier. The scientific novelty of the work consists in clarifying the boundaries of the implementation of the formality category in the new conditions of communication using the example of the lexico-semantic group of feminitives. As a result, it has been found that there are practically no intersections between the set of units from the list of officially recommended feminitives – the language facts used to denote positions and titles – with the set of the most frequent units used in new media. Even in the few cases of a simultaneous entry of units into the list of official names of positions and professions, on the one hand, and into the list of frequently occurring nominations in the usage of new media, on the other hand, such lexemes, as a rule, coincide only in form – their meanings often diverge. Various ways of formation of feminitives in the official classifier and the usage of new media are also noted.


The reaction of the hexathiapyrazinophane ligand, 2,5,8,11,14,17-hexathia-[9.9](2,6,3,5)-pyrazinophane, with copper(II) dibromide lead to the formation of a binuclear complex. Reaction with copper(I) iodide also gave a binuclear complex, which is bridged by a Cu2I2 unit to form a two-dimensional coordination polymer.


Secondary ion mass spectrometry (SIMS) is a specialized form of surface analysis that is used primarily to determine the elemental and chemical structure of solid materials.1,2 It is based on mass spectrometry which is a family of techniques where elements, molecules, and molecular fragments are sorted based on their atomic/molecular weights. The technique employs a source to excite the material of interest into the gas phase with some portion of it as ionized species. The ions then pass through a mass filter which sorts them based on their mass-to-charge ratio. The resulting mass spectrum gives a representation of the elemental and/ or molecular composition of the material of interest.1-3 Often, the list of molecular fragments in the spectrum can be pieced together to obtain a detailed understanding of the chemical structure of the material.1,3,4 theory


Complex formation of 4-[3,5-bis(2-hydroxyphenyl)-1,2,4-triazol-1-yl]benzoic acid (ICL670, H3Lx), 4-[3,5-bis(2-hydroxyphenyl)-1,2,4-triazol-1-yl]benzosulfonic acid (H3Ly), and 3,5-bis(2-hydroxyphenyl)-1-phenyl-1,2,4-triazole (H2Lz) with Fe3+ and Fe2+ was investigated in H2O and in H2O/DMSO mixtures by potentiometry, spectrophotometry and cyclic voltammetry. ICL670 has previously been considered as a promising drug for an oral treatment of iron overload. In this paper, the stability and redox properties of the various FeII and FeIII complexes were elucidated with a particular focus on their potential involvement in the generation of oxidative stress. The overall stability constants of [FeIII(Lx)] and [FeIII(Lx)2]3− (25 °C, 0.1 M KCl in H2O) are log β1 = 22.0 and log β2 = 36.9, respectively. The affinity of these ligands for Fe2+ is remarkably poor. In particular, the 1:2 complexes [FeII(Lx)2]4− and [FeII(Ly)2]4− were found to be less stable. As a consequence, the redox chemistry of the [FeIII(Lx)]/[FeII(Lx)]− and the [FeIII(Lx)2]3−/[FeII(Lx)2]4− couples differs significantly. [FeIII(Lx)2]3− is a very weak oxidizing agent (E1/2 is approximately −0.6 V versus NHE) and reduction of [FeIII(Lx)2]3− is not anticipated under physiological conditions. The reduction potential of the [FeIII(Lx)]/[FeII(Lx)]− couple is considerably less negative and was estimated to be +0.1 V (versus NHE). The possible roles of the various Fe complexes as catalysts for the Fenton reaction in biological media are discussed. The crystal structures of H3Lx, Na[Fe(Lz)2]·4EtOH, Na[Al(Lz)2]· 4EtOH, and [Cu(Lz)(pyridine)]2 were investigated by single-crystal X-ray diffraction, and the possible influence of the particular steric requirements of these ligands on the stability of the metal complexes has been analyzed. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)


Chediak-Higashi syndrome (CHS) is a rare autosomal recessive immunodeficiency, caused by mutation in LYST-CHS1 gene, encoding the respective protein regulating the lysosomal transport. The syndrome is characterized by early onset, specific clinical features and laboratory signs (oculocutaneous albinism, the presence of peroxidase-positive giant granules in granule containing cells), a high risk of hemophagocytic lymphohistiocytosis (accelerated phase), and is fatal in the majority of cases. Hematopoietic stem cell transplantation (HSCT) is the only curative treatment. The best results of overall survival of CHS patients are attained if HSCT is carried out before the accelerated phase and with the use of reduced intensity conditioning. The authors present the experience gained in the diagnosis and treatment of three patients with CHS of different severity and with complications of the underlying disease. Two patients received HSCT with reduced intensity conditioning in accordance with the international recommendations. The results of catamnesis (duration of follow-up 4 months and 1 year) indicated complete hematological reconstitution.


The use of a digital library (digital library) has been done at the college library. This is done in order to provide ease of library users to access information easily. Similarly, the library UIN Maliki also provide digital library services to the user for easy information retrieval by users. To provide good service to existing users, the quality of the digital library services must also be increased. The quality of digital library services which is served should be easier for users to search information. By providing good quality services, the use of digital library will also improve access to its use by the user. In this study, researchers conducted a quantitative study with a descriptive survey method. The population of this research is a user or users of digital library services Library UIN Maliki. In this study the sampling method used is non-random sampling, using a purposive sample. The criteria are users who have access to a digital library) UIN Maliki. The purpose of this study was to determine the quality of a digital library on the library UIN Maliki. In this study using primary theory that the EServiceQuality of Jesicca Santos. In an e-service quality theory there are 2 dimensions to measure the quality of online services is inkubatif dimensions and dimension active. In inkubatif dimension consists of ease of use, appearance, linkage, the structure and layout, and content. Active dimension consists of reliability, efficiency, support, communications, and security. Of both dimensions can be seen that the dimension of assessment inkubatif most prominent is mengedapan or assessment of the linkage and the dimensions of the most active or prominent mengedapan is communication assessment. It can be concluded that the assessment of user satisfaction on the service life of already open access user satisfaction 60% higher than the ratings categories are not satisfied by 40%


Propeller installation options for a twin-engined turboprop aircraft are evaluated at cruise conditions, aiming to identify the quieter configuration. Computational fluid dynamics is used to investigate the near-field acoustics and transfer functions are employed to estimate the interior cabin noise. Co-rotating and counter-rotating installation options are compared. The effect of propeller synchrophasing is also considered. The employed method captures the complexity of the acoustic field generated by the interactions of the propeller sound fields among each other and with the airframe, showing also the importance of simulating the whole problem to predict the actual noise on a flying aircraft. Marked differences among the various layouts are observed. The counter-rotating top-in option appears the best in terms of acoustics, the top-out propeller rotation leading to louder noise because of inflow conditions and the occurrence of constructive acoustic interferences. Synchrophasing is shown to be beneficial for co-rotating propellers, specially regarding the interior noise, because of favorable effects in the interaction between the propeller direct sound field and the noise due to the airframe. An angle closer to the maximum relative blade shift was found to be the best choice, yielding, however, higher sound levels than those provided by the counter-rotating top-in layout. ∗Corresponding author Email addresses: email@example.com (Giulia Chirico), firstname.lastname@example.com (George N. Barakos), email@example.com (Nicholas Bown) Preprint submitted to Journal of Sound and Vibration February 24, 2018