In this paper, we quantitatively evaluate the role of texture in hair patches, with a primary motivation of understanding what can be learned and applied by machine learning systems for texture-based hair detection. We evaluate the distribution of gradient directions in hair patches, and explore the relation between proximity to the face and the angle of the gradients for 2,870,000 hair patches selected from 100 manually silhouetted hairstyles.


OBJECTIVES
Tight control studies including regular assessments of disease activity have shown that this approach has beneficial effects on disease activity, disability and joint damage in treating RA patients. Some of these studies included tight control with protocolized treatment, while others applied tight control without protocolized treatment. The aim of this study was to compare the effects of tight control with usual care and to compare the effects of tight control studies with and without protocolized treatment adjustments.

METHODS
A systematic literature search was performed to identify clinical trials in RA that evaluated tight control strategies in comparison with usual care. Two types of study were compared: (i) those using disease activity monitoring with protocolized treatment adjustments, and (ii) those using disease activity monitoring without protocolized treatment adjustments. The databases PubMed and Cochrane were searched from 1995 up to 2009. Primary outcome measure was the mean change in the 28-joint DAS (DAS-28), which was used in a random-effects meta-analysis.

RESULTS
Six controlled trials regarding tight control in RA patients were included in the meta-analysis. In all trials, patients treated in the tight control arms had significantly higher DAS-28 responses than patients treated according to usual care [weighted mean difference (WMD) = 0.59, P < 0.001]. Moreover, tight control was significantly more effective (P < 0.001) by means of protocolized treatment adjustments (WMD = 0.97) compared with non-protocolized monitoring of disease activity (WMD = 0.25).

CONCLUSION
Tight control in RA resulted in significantly better clinical outcomes than usual care. It is suggested but not proved that tight control with protocolized treatment adjustments is more beneficial than if no such protocol is used.


Sweet basil (Ocimum basilicum L.) is a popular culinary herb belongs to the family Lamiaceae. Basil also named as great basil or saint-joseph-wart. Leaf of basil has a pungent & strong taste some Asian basils have a clove like flavour. Basil used as a culinary herbs have been reported to posses antioxidant activities. A field experiment was conducted at the research farm of CSIR-Central Institute of Medicinal and Aromatic Plant,Research Centre, Pantnagar (U.S.Nagar) Uttarakhand.India during kharif season 2018. The highest oil yield observed in T2 Cim-Snigdha (126.99 kg/ha) as compared to T3 Cim-Soumya (108.64 kg/ha), T5 Cim-Surabhi (86.22 kg/ha) as compared to others. The lowest oil yield (37.90 kg/ha) recorded in T4 Cim-Jyoti. Oil yield also differ at different harvest stages of different Ocimum sp. The highest oil yield 142.69 kg/ha observed at 100% flowering stage (S4) as compared to 138.56 kg/h at seed setting stage (S5), 63.60 kg/ha at 50% flowering stage (S3), and 56.63 kg/ha at bud initiation stage (S2). The lowest oil yield 25.54 kg/ha recorded at pre budding stage (S1). The highest oil yield 267.00 kg/ha was recorded in T3S4 interaction of variety and harvest stages (Cim-Soumya at 100% flowering) as compared to other treatments. Therefore recommended the Ocimum should be harvest at 100% flowering stage to get maximum oil yield and return to the farmers as compared to other.


Psychicones: Visual Traces of the Soul in Late Nineteenth-Century Fluidic Photography Nicolas Pethes 325 'It's All Done With Mirrors': V.S. Ramachandran and the Material Culture of Phantom Limb Research Katja Guenther 342 Drawing as Instrument, Drawings as Evidence: Capturing Mental Processes with Pencil and Paper Alicia Puglionesi 359 Brain Ways: Meynert, Bachelard and the Material Imagination of the Inner Life Scott Phelps 388


HER2 positive breast cancer accounts for approximately 20-25 % of breast cancers. Trastuzumab, a humanised monoclonal antibody, is approved for the treatment of HER2 positive breast cancer. However, the majority of metastatic HER2 positive breast cancers progress on trastuzumab treatment due to either innate or acquired resistance. The aim of this study is to investigate the role of microRNAs (miRNAs) in a cell line model of acquired trastuzumab resistance. The trastuzumab resistant cell line, SKBR3-T was established by continuous exposure to trastuzumab (10 µg/ml) for 6 months. miRNA extracted from SKBR3 and SKBR3-T was profiled using Taqman low density arrays (TLDA). Differentially regulated miRNAs were selected using >2-fold change and a P-value of Six differentially regulated miRNAs were identified in the SKBR3-T cells. qRT-PCR assays confirmed that four were significantly altered in SKBR3-T compared to SKBR3 cells including miR-9 which was 2.2 fold up-regulated (p=0.04). Utilising miRWalk, we identified RARA as a target for miR-9. We confirmed that RARA mRNA and protein expression are reduced in SKBR3-T cells compared to SKBR3 cells. Treatment with all-trans retinoic acid (ATRA) (0.2 µM–0.025 µM) alone inhibited growth of the SKBR3 cell line in a dose dependent manner but not in the SKBR3-T cell line. Combined treatment with trastuzumab (10 µg/uL) and ATRA (0.2 µM) had a significantly greater growth inhibitory effect on the SKBR3 cell line (90.1±5.2 %) (p=0.0002) than either trastuzumab (39.1±4.0 %) (p= 0.0004) or ATRA alone (57.9±4.2 %) (p=0.001). Interestingly, despite relative insensitivity to ATRA in the SKBR3-T cells (23.7±5.0%) (p=0.86), combined treatment with trastuzumab produced significant growth inhibition in the SKBR3-T cells (74.2±5.1%) compared to either trastuzumab (24.1±4.4%) (p=0.0001) or ATRA (23.7±5.0%) (p=0.86) alone. miR-9 is up-regulated in the acquired trastuzumab resistant SKBR3-T cell line, RARA expression is downregulated, and SKBR3-T cells are resistant to ATRA treatment compared to SKBR3 cells. However, SKBR3-T cells are sensitive to combined treatment with trastuzumab and ATRA. Thus combined treatment with ATRA and trastuzumab may overcome acquired resistance to trastuzumab in HER2 positive breast cancer. Citation Format: Karen Howe, Brigid C Browne, Sinead Aherne, John Crown, Norma O9Donovan. miR-9 expression, retinoids and their potential role in trastuzumab resistance [abstract]. In: Proceedings of the Thirty-Seventh Annual CTRC-AACR San Antonio Breast Cancer Symposium: 2014 Dec 9-13; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2015;75(9 Suppl):Abstract nr P4-07-06.


Efficient medium access control (MAC) is desirable for underwater sensor networks (UWSNs). However, designing an efficient underwater MAC protocol is challenging due to the long propagation delay of the underwater acoustic channel and the spatial-temporal uncertainty. In this paper, we propose a novel Traffic-Adaptive Receiver-Synchronized underwater MAC protocol, TARS, a stochastic light-weight channel access scheme that addresses the spatial-temporal uncertainty for maximizing the network throughput. We adjust the packet transmission time (phase) in a slot, which is dependent on the sender-receiver distance, to align packet receptions for collision reduction. Both the sound propagation speed variation and the node mobility are considered in setting the optimal transmission phase and the slot size. We employ a queue-aware utility-optimization framework to determine the optimal traffic-adaptive transmission strategies dynamically, taking into account both the packet interference and the data queue status. Extensive simulation results show that compared to the existing representative underwater MAC protocols, TARS achieves better performance with higher network throughput and lower packet end-to-end delay.


Incorporation of whey protein concentrate (WPC) at a level of 1, 2, 3 and 4% in buffalo meat was investigated for production, quality characteristic and shelf life of buffalo meat emulsion sausage (ES). Quality of emulsion sausage was evaluated in terms physicochemical characteristics like moisture content, pH, protein content, water holding capacity (WHC), Extract release volume (ERV), microbiological characteristics like total plat count (TPC) and Yeast and mold count (Y&M), Coliform count, and sensory characteristic including instrumental colour measurement. It was found that moisture content, ERV, pH and WHC were significantly (P<0.05) decreased of emulsion sausage in period of storage at 0o C as result of incorporation of 1-4% of WPC. But protein content significantly (P<0.05) increased in period of refrigerate storage. TPC, Y&M and Coliform count of emulsion sausage were found in range of 7.11-7.39 log cfu/g, 3.34-3.86 log cfu/g and 2.25-2.54 log cfu/g respectively. Emulsion sausage incorporated with whey protein concentrate was acceptable to the panelist. The numerical value of 'L' for the samples in 25 th days of storage condition found in the


The environment is a set of parts with all the substance, effort, nature and inhabitants of the world, including human beings and their behavior that controls the life and peace of humans and other living things. The current natural problems are very alarming, lack of awareness, knowledge, understanding and ignorance so that they do not do, do not do, pretend not to know, do not like to read, even the other most dangerous cause is a greedy temperament that wants to find its own benefits. All of these cause environmental damage. With the existence of the adiwiyata program, the school population is obliged to preserve and preserve environmental knowledge through the principle of running an efficient school to uphold sustainable development. This study aims to determine the relationship of the adiwiyata program to environmental character education. The questions to be answered through this research are: 1. The adiwiyata program at MAN 1 Jombang. 2. Character education care for the environment at MAN 1 Jombang. 3. How is the relationship between the adiwiyata program and environmental education character education. This study uses a type of field correlation research. The approach used in this research is a quantitative approach. The design of this study was expost facto. Researchers took a sample of 60 respondents from 6 classes each class taken 10 people randomly. Hypothesis testing in this study uses the Spearman correlation. Thus, the researcher tried to explain the relationship between the adiwiyata program and environmental care character education at MAN 1 Jombang. From the analysis it was found that known sig of 0,000 (sig <0.05), means that H0 is rejected and HA is accepted. This means that there is a relationship between variable X (Adiwiyata Program) and Y (Environmental Care Character). Then it is also known that the coefficient value is 0.940 (positive value), which means a positive correlation (proportional), where the greater X then Y is also greater.


The earthquake of 1546 is considered to be one of the largest shocks in the Middle East associated with surface faulting and great loss of life. The examination of contemporary documents shows that this seismic event was a medium magnitude earthquake of Ms about 6.0, in many respects similar to that of the earthquake of 1927, that is, one of those early and grossly exaggerated events which excited widespread interest rather on account of the geographical location than because of their size or special violence. We cpud find no evidence of faulting or excessive damage and no justification to regard this earthquake as one of the most destructive in the Jordan Rift Valley.


The basic aspects of the structural analysis of cable-stayed bridges in the service stage are discussed. After a brief introduction on the prerequisites of the cable-stayed statical arrangement, the impact of the material constitutive laws on the delayed structural behaviour is pointed out. The linear viscoelastic law of concrete is extensively discussed by introducing the most important models and the basic methods of structural analysis. For the stays, a linear elastic behaviour is generally adopted, but for long stays the concept of reduced elastic modulus is introduced in order to take into account the effects of cable sagging. The service stage behaviour of cable-stayed bridges is then theoretically investigated and various structural configurations are discussed, with reference to the level of rheological non homogeneity affecting the bridge.


. One aspect to determine the quality of a study program or educational institution is to look at the quality of the alumni of the study program . The purpose of the tracer study is the PG PAUD Education Study Program, Universitas PGRI Semarang to determine the output of education, namely an assessment of mastery and obtaining competencies possessed by alumni and to find out the educational process in the form of evaluating the learning process and the contribution of higher education to competency acquisition. Source of data is alumni batch 2013-2015 in Kendal Regency. The results of the study, The average length of waiting period for alumni is 1 year, 85% of alumni work according to their choice of study, the majority of alumni work in educational institutions, performance benefits alumni, it is known that 60% are useful for agencies, 70% are managerial skills, 60% are skilled at managing tasks, 75% are skilled at managing human resources, and 65% are skilled at motivating


A method and an oligonucleotide probe are described for determining the presence or absence of mutant alleles in a genomic locus. The probe binds to different alleles of a target sequence with different melting temperatures (Tm). The method determines the Tm of the probe when it is hybridized to the target sequence to establish whether a variant nucleic acid such as a mutant allele is present or absent in the target sequence. There may be variants in a target sequence that are not of interest, for example phenotypically silent mutations. To ensure that these variants do not influence the Tm of the probe, the probe contains universal base sites where such variants of no interest occur.


This study examines the behavioral commitment (intent to stay) of a sample of blue-collar employees from a manufacturing firm in Australia. The purpose was to test an integrated causal model of behavioral commitment based on four general classes of variables: structural, pre-entry, environmental, and employee orientations. The LISREL results indicate that variables rank ordered in terms of importance for their total causal effects on the decision process of employees to stay or leave an organization is as follows: job search, job satisfaction, job security, attitudinal commitment, union participation, environmental opportunity, physical conditions, job hazards, met expectations, equity, family responsibility, centraliza tion, supervisory support, and work group cohesion.


The most essential problems in Regge calculus discretization are the definitions of the partition function and the integral measure for link--length. In recent work, by considering the one--dimensional case, it was suggested that we should define the partition function in a certain form. But in that work, the model which authors used was over simplified hence the conclusions may be unreliable. To confirm their claim, we consider a case that is more realistic.


As the cost of higher education increases, lack of funds has already become a bottleneck problem in the development of universities and colleges. However, shortage of funds have been made more serious owing to the prolonged neglect of the beneficial results of investment in higher education and poor management. The author points out that new channels must be found to increase investment in higher education and meanwhile internal management must be reinforced and the available resources be reorganized to revitalize funds, thus raising the fund utilization rate and improving the results of investment.


The work of fire departments is influenced by various factors that bring risks. The security of fire fighters is the most important thing when performing their job. Therefore, it is necessary to ensure their security by identifying risks and eliminating them in advance. Virtual reality resources help to increase the safety of firefighters during professional training activities. These activities are conducted with the usage of simulators, practical exercises and simulations; however, these exercises can only partly get them closer to reality. We claim that virtual reality is a huge aid for firefighters, and that by using this tool, efficient protection of life and health as well as property can be provided. The submitted article discusses the current state of virtual reality resources and their use in the professional training of fire brigades and rescue units. It also discusses the benefits of virtual reality use.


At the College Art Association 2003 annual conference, the editorial board of Art Journal convened a round-table discussion on the art history survey: why it continues to exist, who teaches it and how is it taught, and what have been effective challenges and innovations to its traditional form. Participants engaged in a spirited, substantive, and inconclusive discussion. Organizer and moderator Peggy Phelan (then chair of the Art Journal editorial board) proposed that this conversation on pedagogy should continue. She convened a round-table discussion, via e-mail, on the survey course with several experienced teachers and scholars. During the course of the conversation, Kathleen Desmond noted, "The Carnegie Foundation found that 80 percent of college teaching faculty listed teaching as their primary interest. Yet we barely discuss teaching. Treating teaching in the same ways we treat research and art making can revitalize and legitimize the essential component of our jobs as college professors." With these points in mind, we are publishing excerpts from the e-mail discussion, hoping it might provoke further consideration of and dialogue about teaching the arts and art history in the new century.


Benefits from laser Peening have been demonstrated several times in fields like fatigue, wear or stress corrosion cracking. However, in spite of recent work on the calculation of residual stresses, very few authors have considered a finite element method (FEM) approach to predict laser-induced mechanical effect. This comes mainly from the high strain rates involved during LP (10 6  s -1 ), that necessitate the precise determination of dynamic properties, and also from the possible combination of thermal and mechanical loadings in the case of LP without protective coatings. In this paper, we aim at presenting a global approach of the problem, starting from the determination of loading conditions and dynamic yield strengths, to finish with FEM calculation of residual stress fields induced on a 12% Cr martensitic stainless steel and a 7075 aluminium alloy.


In his 1922 / and Thou Martin Buber presents himself in the role of physician engaged in curing humanity's "times of sickness."1 Humanity is sick, Buber claims, because people have lost access to their fundamental state of being, their "ontological orientation," which he describes in this text as the I-thou relation and later as the dialogical situation. In his essay "Renewal of Judaism" published in his 1911 Drei Reden uber das Judentum Buber addressed what he called "the danger to the Jewish people: that it may lose the life of the spirit,"2 a danger that anticipates his more general and not ethnically specific 1922 characterization of "our times of sickness."3 The question that I'd like to address in this essay is: what is the relation between Buber's view of a renewal of the specifically Jewish past and the claims about ontological truth that he would develop more broadly in / and Thou as well as many of his later philosophical works (including first and foremost his most philosophical works Das Problem des Menschen and Gottesfinsternis)! In "Renewal of Judaism" Buber describes his view of Jewish "renewal" this way:


When assessing the environmental impact of petroleum hydrocarbon exploitation, it can be challenging to differentiate anthropogenic from natural hydrocarbon sources. For example, areas underlain by permafrost may be affected by erosion of hydrocarbon‐rich deposits from thermokarst activity, complicating environmental assessments of human impacts from petroleum extraction. Here we examined polycyclic aromatic compounds (PACs) and metals in sediment cores from lakes affected to varying degrees by thawing permafrost. We used a paired‐lake design on lakes with pronounced shoreline retrogressive thaw slumps and compared them to nearby lakes in undisturbed (no retrogressive thaw slump) systems in the Mackenzie Delta uplands (Northwest Territories, Canada). Total organic carbon (TOC)‐normalized concentrations of parent and alkylated PACs were higher in surface sediments of slump‐affected lakes. Slump‐affected lakes were also enriched in metals related to local shale‐based, Quaternary deposits (e.g., Ca, Sr, and Mn) when compared to reference lakes where surficial materials were not exposed by thermokarst activity. Diagnostic ratios of specific PACs suggested that slump‐affected lakes also had a greater influence from petroleum‐based compounds, likely sourced from the local geology. Higher PAC concentrations and petrogenic composition were best explained as a combination of low TOC availability and increased inputs of previously bound hydrocarbons from the catchment due to permafrost erosion.


This book would be of interest to students applying to medical school as well as those currently in the early stages of the curriculum. It summarises the different curricular stages in medical school, from lectures and study modules to ward work and exams.

Preclinical students may find the book a useful introduction to …


Rice plant (Oryza sativa L.) has various varieties. People generally prefers to rice with good taste and aroma. The aroma is part of the physicochemical properties of the rice plant. The aroma of rice arises because of the gene that controls the nature of the aroma. PCR (polymerase chain reaction) is an in vitro method for generating a large amount of specific DNA fragments with defined lengths and sequences in a small number of complex templates. The objective of this study was to analyze the genetic diversity of some Indonesian local rice varieties based on SSR marker related to aromatic genes. The selected Simple Sequence Repeat (SSR) primers associated with aromatic genes were: RM 484, RM 410, RM 251, RM 247, RM 223, and RM 9. Based on the DNA band pattern, 6 primers were derived, in which there were 14 loci related to the aromatic gene. The resulting dendrogram showed that two main groups of rice achieved a 57% similarity. Group A consisted of aromatic rice accessions, i.e. Rojolele, Rabeg, Rumbah, Cere Lintang, Manikam, Cao, Jawara Hawara, Jalawara, Pare Racik, Godok, Mayang, Caragol, Segubal, Konjal, Beuruem Batu, Tambleg, Parajaketra, Pondok Leger, Seungkeuhan, Waren, Pare Emas, Kapundung, and Cireh Hudang. Group B consisted of non-aromatic rice accessions, i.e. Ciherang, Care Wari, Care Beuruem, Cokrom, Kewal Bulu Hideung, Maninjau, Seren, Sidenuk, Tampai Beureum, Mira, and Pare Caok.


The focus of this work is clinico-genomic decision support system for better diagnosing and managing chronic diseases. We propose a clinical decision support system for early diagnosis of chronic diseases(such as arthritis, Diabetes, Cardio Vascular Disease) and better disease management. We propose a generalizable framework, which can accommodate several distinct features coming into the system from clinical, genomic, environmental domains among others. We utilize this framework to discover similar patients and overlaps among patients in a set of these features which has several applications such as : (a) better cohort discovery for clinical trials, (b) better disease management by studying peer group of patients with similar diagnosis and better prognosis, (c) early disease diagnosis by studying similar features in patients with existing diagnosis


Abstract The formation of incommensurate structures and their breakdown in the system of domains is shown with the help of a generalized thermodynamic potential describing Williams domains in nematic liquid crystals above the electrohydro-dynamic instability threshold.


PrefaceChapter One: Introduction: The Relevance of the Past in the PresentChapter Two Lessons from the PastChapter Three Improving the Prospects for a Sustainable WorldChapter Four Is Warfare Inevitable? Chapter Five Why Cities?Chapter Six Preserving the World's Historical HeritageChapter Seven Future DirectionsChapter Eight EpilogueAppendix Following Up the Book's Themes: An Introductory GuideEndnotesReferencesIndexAbout the Author


High-strength concrete (HSC) is vulnerable to strength loss when exposed to high temperatures or fire, risking the structural integrity of buildings and critical infrastructures. Predicting the compressive strength of HSC under high-temperature conditions is crucial for safety. Machine learning (ML) techniques have emerged as a powerful tool for predicting concrete properties. Accurate prediction of the compressive strength of HSC is important as HSC can experience strength losses of up to 80% after exposure to temperatures of 800°C–1000°C. This study evaluates the efficacy of ML techniques such as Extreme Gradient Boosting, Random Forest (RF), and Adaptive Boosting for predicting the compressive strength of HSC. The results of this study demonstrate that the RF model is the most efficient for predicting the compressive strength of HSC, exhibiting the R 2 value of 0.98 and lower mean absolute error and root mean square error values than the other applied models. Furthermore, Shapley Additive Explanations analysis highlights temperature as the most significant factor influencing the compressive strength of HSC. This article provides valuable insights into the timely and effective determination of the compressive strength of HSC under high-temperature conditions, benefiting both the construction industry and academia. By leveraging ML techniques and considering the critical factors that influence the compressive strength of HSC, it is possible to optimize the design and construction process of HSC and enhance its resilience to high-temperature exposure.


: The planet's state concerns every one acquiring eco-friendly behaviors since their youngest ages is essential the works in marketing are relatively not many and do not aprehend the way he cosumer is aware for food waste and in particular the child. Therefore, we propse in this work to study the sensitivity of Tunisien and switzeland children to food waste. We are more specifically interested in the category of 7-12 years old because it is this age that the child understands moral values, and becomes aware of these gestures. 24 semi-structured interviews with children revealed that while they have a respectable level of knowledge of different aspects related to the environement (pollution, ecological problem…) but their sensitives as well as their behavior towards food waste appear to be limited.


This paper investigated the fracture behavior of the unavoidable breakage of carbon fibers and fiber orientation of short carbon fiber reinforced polycarbonate composite in injection process. In this experiment, short carbon fiber mixed compound of 1mm, 3mm, 5mm, 7mm length with 10wt.%, 15wt.%, 20wt.% in polycarbonate for injection molding were produced through the extruder. The dumbbell specimens for tensile evaluation were made by injection molding. The parent specimens were made by double gate method, the weld specimens were made by single gate method which was controlled by inserting a stopper through the runner of the mold cavity. Short carbon fiber reinforced PC composite was evaluated by micro-CT with regard to the particle size of short fiber with a diversified quantitative analysis through entire process of the injection process in composite. The quantitative distribution of fiber orientation was also examined by micro-CT with regard to normal direction or anisotropy. Weld line of short carbon fibers reinforced PC composite weaken the bonding strength by 50% compared to parent materials because the weld line is composed with concentrated anisotropy orientation of short carbon fiber in weld line. Evaluation of the mechanical properties of the injection specimens group was utilized by universal tensile strength tester. In addition, fracture surface of parent and weld materials was investigated by a SEM.


Results for the energy dependence of the elementary kaon production cross sections in proton-proton collisions are reported. Calculations are performed within an extended version of the resonance model which was used for the previous studies of elementary kaon production in pion-nucleon and pion-∆ collisions. Although the model treatment is within the empirical tree level (observed widths for the resonances are used), it is fully relativistic, and includes all relevant baryon resonances up to 2 GeV. This article reports a part of the systematic studies performed using the resonance model. This is the first, consistent study of the elementary kaon production reactions including both πB and BB (B = N,∆) collisions on the same footing. Comparisons are made between the calculated results and the existing semi-empirical parametrizations, as well as the experimental data. Strangeness production in heavy ion collisions is presently an issue of intense study. The enhancement of strangeness production in heavy ion collisions might indicate evidence for a new form of nuclear matter, such as a quark gluon plasma [1, 2]. Particularly, kaon production in heavy ion collisions is considered a promising method not only of obtaining information about hot, dense nuclear matter, but also of determining the nuclear equation of state [3, 4]. For the study of kaon production in heavy ion collisions, the elementary cross sections in pion-nucleon and baryon-baryon collisions are some of the most basic and important ingredients for the microscopic calculation of the total kaon yield. However, the available experimental data for the baryon-baryon collision channels are very scarce (most exist for pp collision channels) and thus could not be parameterized in a satisfactory way for practical use. Indeed, there are drastic differences between the commonly used, semi-empirical parametrizations for (the energy dependence of) the total kaon production cross sections in baryon-baryon collisions proposed by Randrup and Ko [7], and Schürmann and Zwermann [8]. Thus, one has to parametrize these cross sections by relying on the theoretical investigations. Supported in part by the Australian Research Council and the Forschungszentrum Jülich firstname.lastname@example.com firstname.lastname@example.com firstname.lastname@example.com


Progress is shown in matching SYNTHE spectral calculations to the observed high-resolution spectra of standard stars. In the mid-UV these are the Sun, Procyon, and solar-type stars ranging in metallicity. Redward of 3000A, the K giant Arcturus is added. In the mid-UV, from 2300Ato 3000A, good reproduction of individual spectral absorption lines in solar-type stars is achieved to an iron abundance [Fe/H] = –0.5. At higher metallicities, many atomic lines appear which are unidentified in the laboratory and so are missing from the calculations. We are fixing this with STIS echelle spectra already in hand. In the near-UV, 3000A– 3800A, good agreement is found at solar metallicity for solar-type stars, but missing atomic lines pose problems for Arcturus. In the optical, the fit to Arcturus is not good from 4090Ato about 4500A, due to lines of the molecule SiH, whose wavelengths are poorly known. Beyond 4500A, excellent agreement is seen in regions of low to moderate telluric molecular absorption, for all stars considered.


A call for greater transparency following various corporate scandals in a volatile global economy has placed intense pressure on South African corporations to reform, not only their conduct but also their reporting. As investors and other stakeholders insisted on the assurance that company practices were transparent, accountable and fair to all stakeholders, the JSE changed listing requirements to oblige listed companies to integrate their sustainability reports with their annual reports. To understand how companies incorporate integrated reporting standards in voluntary narrative disclosures, this article reports on how chairpersons of 50 high-performing and 50 poor-performing companies listed on the JSE included content elements within their statements. Qualitative content analysis was used to analyse how content elements were presented and communicated in the 2012 chairpersons' statements. Findings indicate that South African companies embraced new reporting requirements. Just as the King Reports have been praised as an internationally leading code of governances, annual corporate reports of JSE-listed companies can become an international benchmark for integrated reporting. Even though the chairperson's statement does not present the platform to discuss all the content elements in detail, the content elements of integrated reporting seem to provide a useful framework for chairpersons on what to include in their chairperson's statement.


The rapid evolution of real-time multimedia applications requires Quality of Service (QoS) based multicast routing in underlying computer networks. The constrained Steiner Tree, as the underpinning mathematical structure, is a well-known NP-complete problem. In this paper we investigate a variant of variable neighborhood search, variable descent search, for the delay-constrained least-cost multicast routing problems. The neighborhood structures designed in the variable descent search approaches are based on the idea of path replacement in trees. They are simple, yet effective operators, enabling a flexible search over the solution space of this complex problem with multiple constraints. A large number of simulations demonstrate that our algorithm is highly efficient in solving the delay-constrained, least-cost multicast routing problem in terms of both the total tree cost and the execution time. To our knowledge, this is the first study of variable neighborhood search on the delay-constrained, least-cost multicast routing problem. It outperforms other algorithms and heuristics over a range of problem instances.


A selectively laser sintered human tracheobronchial airway model was used to study periodic flows at different frequencies corresponding to inhalation and exhalation. The model was fabricated from a 3-d point could based on the Visible Human Male Project. The objective was to document the volumetric flow rate and pressure drop under periodic flow conditions and compare these values with those obtained in steady flow. The flow was cycled via a Programmable Logic computer (PLC) at a specified breathing frequency of 12 breaths per minute. The tracheal flows rate studied were 30, 50, and 120 liters per minute. The results indicated that significant differences existed between flow measurements made under steady conditions and periodic conditions; these differences became significant at high flow rates. The flow distribution in the right and left side of the airway model was asymmetric. The results also indicated the existence of both turbulent and laminar flow regimes at all tracheal flow rates.Copyright © 2004 by ASME


This paper deals with the problem of earthquake response analysis of pipelines, empty or fully filled with liquid and buried at a finite depth below the ground surface. Emphasis is placed upon searching for the effect of boundary surface on the responses for different buried depths. Comparative studies are made on the relation of various response variables to buried depths and liquid filling conditions, etc.


Chicago, Illinois, November 1961, the 47th annual meeting of the Radiological Society of North America in the Palmer House hotel in the Chicago Loop—that meeting was my first as radiology news press officer.


With the improvement of people'living standards,the incidence rate and fatality rate of coronary heart disease are obviously rising. Percutaneous coronary intervention( PCI) is currently one of important treatment means to patients with coronary artery disease,and information intervention is conductive to changing bad mode,establishing healthy mode,and enhancing living quality of patients after PCI operation.


This research aims to know how the influence of Total Quality
Management and Environmental Uncertainty on Managerial Performance of manufacturing
company in Surabaya. This is causative research. The population are 10 manufacturing
companies in Surabaya. The samples are the financial manager, production manager, research
and development manager, marketing manager, and human resources manager as
much as 32 managers. The data is the primary data using questionnaires. Processing data
is using software SPSS 23.0 with multiple regression analysis of data with the F test, R Square
test, and T test. The results of this research indicate (1) Focus on the Customers has no
positive effect on Managerial Performance of manufacturing company in Surabaya, (2)
Employee Empowerment has
positive Managerial Performance against Managerial Performance of manufacturing
company in Surabaya (3) Commitment on quality has no positive effect
on Managerial Performance of manufacturing company in Surabaya
(4) Continuous Improvement has no positive effect Managerial Performance of manufacturing
company in Surabaya (5) management based on the fact has
positive effect Managerial Performance of manufacturing company in Surabaya
(6) Environmental Uncertainty has negative effect on Managerial Performance of
manufacturing company in Surabaya.

Keywords: TQM, Environmental Uncertainty, Managerial Performance


At the National Institute of Research and Development for Potato and Sugar Beet – Brasov, Romania field experiments were carried out in order to collect data on quantitative traits (plant height, number tubers, tuber size, tuber weight) and yield of some new potato genotypes. It was used a complet randomized block design with four replicates. The number of steams varied between 14.5 steams / hill on genotype 1947/2 and 5.5 steam / hill on genotypes 1979/5 and 1901/12. The lowest value of the median leaf length was recorded at clone 21-1901/7 (56 cm) and the highest at clone 1947/2 (181 cm). Brasovia variety (control) has a poorly developed root system (48 g), also the genotypes 1891/7, 21-1895/1, 21-1901/7. Instead, genotypes 1901/6, 1927/1, 1971/9, 1965/16 have a high weight of the root system. Most spectacular production was provided by the line 1979/5 (77.90 t/ha), followed by the lines 1901/7 (45.55 t/ha) and 1939/2 (47.93 t/ha). The lines 1895/4, 1876/7, 1971/9, 1927/1, 1968/2, 1897/2, 1968/1 and 1947/2 also recorded significantly high productions.


The plastic moment capacity of castellated steel beams should be reduced to lower the Mpl beam. Higher Mpl beam will require bigger column section to avoid failure/yielding in the column section. The research aims to analyse the behaviour of beams ductility of castellated steel beams using "dogbones." The research used four types of test beam to check the influence of "dogbones" that are made of steel beams IWF 150 x 100 x 5 x 7. They are normal castellated steel beam, variation in the length of dogbones, and variation in the deep of dogbones. The results show that the plastic moment capacity of castellated beams is higher than normal beam. It is, therefore, necessary to reduce the plastic moment capacity of castellated steel beam by using "dogbones." It will maintain ductile behaviour of the steel structure. Concrete was discussed.


This invention particularly relates to the field of engine washing with only such cleaning liquid water and detergent or water, more particularly, a system for processing and collecting waste water from engine washing operations, device, and such a system on the mobile cart containing a. The system includes a collection device for collecting waste liquid during the cleaning operation of the engine, and a processing device for processing liquid waste that is collected in the cleaning operation. According to one embodiment, the system includes an engine for servicing the engine (1) during cleaning operations (1), are arranged on a movable cart (50) comprising a chassis equipped with wheels. The movable cart, the engine (1), for adjusting the vertical position of the adjustment means (73) and / or the liquid collecting means for adjusting the vertical position of the liquid separating means (31) (302,36) including adjustment means.


The present invention relates to a method of reduction treatment using tablets or pellets of a number of biocidal treatment by a chlorine-based oxidizing agent or oxidizing agent oxygen-based metal, sodium sulfite.


He was inoculated with benign tertian on Septenmber 8th, 1922. During the attack of malaria and for some weeks afterwards his mental condition underwent a change. From being apathetic and lacrymose he developed well marked auditory and visual hallucinations, and also delusions of persecution, which for a time made him ,very troublesome with his food. Gertsmann refers to similar cases and seeks to explain the presence of the auditory hallucinations by the greater infiltration of the temporal lobes. The patient, however, made a good recovery and was discharged. Hle has since written a letter to his medical officer which shows that he has at present remarkably good insight. On his discharge (June 30th, 1923) the following notes were made: Yerrous System.-Pupils: right, slightly irregular, reactions (direct and consensual) to light sluggish; left, dilated, oval reactions to light, direct sluggish, consensual absent. All superficial reflexes equal and present; tongue, no tremors; speech, no impediment. Riaht knee-jerk diminished; left knee-jerk diminished; sensations niormal, gait normal; Rombergism absent. Plantars flexor; sphincters normal. In good bodily condition. Cerebro-spinal fluid: Lange gold test, zone 2 curve; gamboge, precipitation in all five. tubes; cell count 61; Wassermann test positive. Blood: Wassermann test positive 1 in 5. CASE Ir. J. A., male, aged 36. Admitted October 11th, 1922. History.-Patient is unmarried. He is stated to have had ordinary health prior to being wounded in the head during the late war. Ile was, however, in the army until September, 1919, and was able to follow his employment until July, 1922, wlhen he complained of severe headaches. No history of his having contracted syphilis has been given. On admission he was rambling and incoherent in conversation, disorientated, wet and dirty in habits. He usually lay in bed with his legs drawn up, and his face partially or wholly covered with blankets. He was in poor bodily health; unable to walk; his weight was 9 st. 4 lb. On examination, the cardio-vascular and respiratory systems were iormal. The pupils were small, unequal, irregular, and sluggish; tongue and lips tremulous; speech slurring; knee-jerks Positive plantars both flexor; showed intention tremors in hands. The blood and cerebro-spinal fluid both gave a positive Wassermann reaction; Lange gold test, zone 1 curve; gamboge tesb, precipitation in all five tubes; protein tests, positive; cell count 24. He was inoculated with benign tertian on January 25th. At the end of March he was noted to have improved a little mentally--he was not so apathetic; there was also a slight improvement in his plhysical condition and he was just able to walk. In another month hiis condition improved both mentally and phlysically; he still remained wet and dirty in habits, but was able to walk a great deal better. By the end of June he was no longer wet and dirty in habits. His weight had increased by 2 st. and he was able -to walk fairly well. At the time of writing lie is in good bodily lhealth, is able to walk fairly well, takes an interest in his surroundings, but his memory is very defective for recent and remote events. CASE III. J. W. B., male, aged 52. This patient contracted svphilis in 1906; lhe was diagnosed as a case of general paralvsis in 1915 in another mental hospital, and was discharged presumably in a state of remission. He was admitted here in December, 1921. From the date of his admission until May, 1922, the disease did not seem to be making much progress so it was decided not to inoculate him with malaria. In the beginning of May, 1923, however, lie had several seizures and his condition began to deteriorate rapidly. He became wet and dirty in habits, and eventually a bodsore developed. It was then decided to inoculate him witlh malaria. This was done on June 9th, and on June 20th he was put on quinine. Since that date he has improved steadily. He is up and able to walk about, the bedsore is practically healed, and his mental condition has improved a great deal. CASE IV. J. B., male, aged 54. On admission the patient was simple and clhildislh; was completely disorientated for time and place. He was in feeble physical condition. Since March of this year he had been confined to bed and he was unable to walk. He had marked tremors of his hands and was unable to do anything for himself. He was inoculated on June 5th. He continued to improve rapidly after inoculation and is now able to walk about. He still has tremors of the right hand, but is able to work in the ward. His mental condition is much better; he is now orientated for time and place. The rapid amelioration of his menital and physical condition was commented on by his relatives.


PREMISE
Distylous species possess two floral morphs with reciprocal positioning of stigmas and anthers that is hypothesized to promote disassortative pollination. Theoretical models predict equal morph frequencies, but many populations depart from the expected 1:1 ratio, a pattern that often correlates with asymmetric mating between morphs and/or presence of a weak incompatibility system. Variation in reciprocity can also affect the likelihood of disassortative pollination and, hence, reproductive fitness.

METHODS
We described variation in incompatibility systems and morph ratio in four Erythroxylum species to test if greater deviations from 1:1 ratios occur in populations of self-compatible species. Using adaptive inaccuracy, we described upper and lower organ reciprocity in species and populations and assessed the relationship of reciprocity to population means and coefficients of variation for fruit set to test if reciprocity could predict female reproductive success.

RESULTS
Morphs occurred in 1:1 ratios in most populations of three Erythroxylum species with distylous self-incompatibility. In self-compatible E. campestre populations showed an excess of the long-styled morph, the short-styled morph, or were monomorphic for the short-styled morph. We detected deviations from reciprocity, with total inaccuracy ranging between 9.39% and 42.94%, and inaccuracy values were lowest in low organs. Across populations, we found a positive relationship between inaccuracy and the coefficient of variation of fruit set.

CONCLUSIONS
Erythroxylum species showed variation in the distylous syndrome, with changes in the incompatibility system that corresponded with deviations from 1:1 morph ratio, and variation in reciprocity that correlated with variation in female reproductive fitness.


The acute toxicity of three kinds of typical Puer tea and one kind of baked green tea from Yunnan province were evaluated in this investigation. The tested mice were feed with tea infusion. The LD50 of the three kinds of Puer Tea was 9.7 g/kg, 11.2 g/kg and 12.2 g/kg respectively, while that of the baked green tea was 7.5 g/kg. None of tested mice died 14 days later, when single feeding dose of four kinds of tea was less than 5 g/kg. Most tested mice showed excitement when the feeding dose less than 1/2 of LD50. The tested mice revealed symptoms of restrained nervous 10 minutes late with the feed dose increased. There was only one peak of the acute lethal time in the case of Pu'er tea, and two peaks appeared in the case of baked green tea. The authors regarded that the death of tested mice was attributed to the high concentration of caffeine and polyphenols. It is concluded that all four kinds of tea are highly safe for drinking according to LD50. However , scientific drinking methods should be mentioned first.


In today's fast-paced digital world outperforming competitors and achieving success becomes utterly challenging for Small and Medium-sized Enterprises (SMEs). The rapid speed of technological change can threaten established industries and undermine existing businesses. By effectively harnessing innovation, businesses can open-up new markets and develop new ways to accommodate the needs of existing customers. Countless research findings reveal that innovation is one of the most essential factors to ensure strategic efficiency and effectiveness in SMEs. Human resources play an integral part in attaining company's goals and objectives. By motivating and encouraging employees to be more innovative, companies can quickly reap the benefits of competitive marketplace. In addition, employees can become a great source of creative and innovative ideas for future endeavors. In this rapidly changing environment, managers should reveal high levels of creativity in offering a plethora of motivational incentives to employees. Increasing employee enthusiasm, motivation and personal commitment remain one of the most enduring and challenging tasks that managers must tackle. Present paper addresses the issue of motivation among Information Technologies (further in the text IT) professionals in fostering innovation. The aim of the paper is to determine the role and significance of motivation in encouraging innovative and creative activities among IT professionals working in the small and medium sized enterprises. The objective of the research is to find the linkage between IT employee's motivation and their contribution to innovation.


Circuit bipartitioning is an NP-hard combinatorial optimization problem in the layout synthesis of VLSI circuits, where we wish to find a partition of the circuit elements into two blocks such that the number of signal nets crossing the partition boundary is minimized. We have developed and experimented with several competitive learning neural network algorithms to solve this problem. The algorithms were tested on randomly generated circuits as well as several popular benchmark circuits. The stochastic reward and punishment neural network produced the best results which were comparable to those found by the Ratio Cut algorithm of Wei and Cheng.<<ETX>>


The invention relates to a house network equipment safety managing system and method, it aims at resolve problem that current mechanism needs handiwork operation to authorization access the equipment and accounts of user and equipment are easy to be embezzled, in the invention, setting a safe managing server for house network in wide wed, setting a safety managing module which is used to provide safety service for inner equipment of house network and contacts with said safety managing server to realize integral safety service in house network; at the same time, exclusive equipment mark is distributed for every user equipment and safety managing module, exclusive network mark is distributed for every house network; said safety managing server and safety managing module realize corresponding house network equipment safety management by distributing and checking said network mark and/or equipment mark.


Moving model experiments are used to investigate the flow around three different train geometries. Due to the difference in the Reynolds number, the flow might not be directly comparable to full-scale measurements. Boundary layer control is used to influence the flow around the train model and increase the boundary layer velocity. With view on the standards given by the Technical specification of Interoperability, the analysis of the wake shows increased maximum induced flow velocities at the specific standard measurement position. 0 Normal 0 21 false false false ES-TRAD JA X-NONE Moving model experiments are used to investigate the flow around three different train geometries. Due to the difference in the Reynolds number, the flow might not be directly comparable to full-scale measurements. Boundary layer control is used to influence the flow around the train model and increase the boundary layer velocity. With view on the standards given by the Technical specification of Interoperability, the analysis of the wake shows increased maximum induced flow velocities at the specific standard measurement position.


Glucagon-like peptide-1 (GLP-1) is a 30 amino-acid hormone produced by the pancreatic islet alpha cells, intes tinal-L cells and central nervous sytem cells. The main target of act ion of GLP-1 is the islet, where the hormone stimulates insulin secreti on, promotes b eta cell proliferation and neogenesis, and inhibits glu cagon secretion. However, GLP-1 receptors are also expressed outside the islets, increasing the likelihood that GLP-1 also plays a role in other organs. These functions are mainly the inhibition of gas tric emptying, gastric acid secretion and exocrine pancreatic secretion, i ndicating that the hormone acts as an enterogastrone hormone released from the distal portion of the small intestine that inhibits proxim al gastrointestinal events. Another important action of GLP-1 is to induce satiety. Other effects of the hormone include cardioprotection, ne uroprotection, induction of antidiabetic actions unrelated to isle t function. Thus, GLP-1 clearly has several manifestations of activit y. The physiologi- cal rele vance of these actions and their contribution to th e overall antidiabetic action of GLP-1 when used in treatment of type 2 diabe- tes remains to be established.


Acute type A aortic dissection is the most serious cardiovascular complication of Turner's syndrome, and is often fatal. We report a case involving a 38 year old woman with karyotype proven Turner's syndrome (46 X iso X), who presented with sudden chest pain. An angiographic computed tomographic scan (right) revealed the …


Dissociation with interference and reciprocal beats have many features in common. They have to be differentiated from one another and from auricular parasystole. Herrmann and Ashman (1930) stressed the importance of the auricular rhythm and polarity of the P waves in the bipolar limb leads as differential criteria between the two rhythms, regular auricular rhythm and positive P waves indicating dissociation with interference. Either may occur when the auriculo-ventricular node is an independent pacemaker, or more rarely, when there is a heterogenetic centre of impulse formation in the ventricles. In both orthograde conduction remains intact although it may be impaired. Retrograde conduction is completely blocked in dissociation with interference whereas in reciprocal rhythm it is not altered, although for reciprocal beats to occur it is usually delayed to a certain critical level. The recognition of these disturbances of conduction is important in clinical medicine, for most reported cases have underlying organic heart disease, or are caused by intoxication such as that due to digitalis or to an increased content of pressor substances in the blood. Their presence can only be detected by graphic methods, and on ordinary clinical examination they are likely to be confused with sinus rhythm, or an idioventricular rhythm with extrasystoles in the ordinary sense. Thus either rhythm may be responsible for one variety of pulsus bigeminus. As early as 1897 Cushny confirmed the existence of two separate foci of stimulus formation in the heart acting simultaneously, the slower rhythm at times interfering with the faster centre of impulse formation: his calculations were made from canine myocardiographic tracings. Later Roth-berger and Winterberg (1910), using the electrocardiograph, noted that transient dissociation with interference occurred in the dog's heart during the development of nodal rhythm. In 1923, Mobitz established dissociation with interference as a pararrhythmia sui generis. It is characterized by the coexistence of two separate foci of stimulus formation in the heart, usually a slow sinus rhythm and a faster nodal rhythm, the slower rhythm at times interfering with the faster rhythm by conducted beats. These conducted beats form the only link between the two centres, and they occur when a sinus impulse reaches the ventricles outside their refractory period. As in parasystole the slower pacemaker is protected against the faster nodal centre by an entrance block. With regard to reciprocal beats, Decherd and Ruskin (1943), have applied the experimental findings of Schmitt and Erlanger (1928) regarding uni-directional …


??What about the good character on the animation? In our past research work, we created a three-dimensional character animation using motion capture data. And then, we tried to make the software to change the three-dimensional animation character into the two-dimensional animation character with a kind of animation movement. The two-dimensional character animation has the different style of movement in comparison with the three-dimensional character animation. In this work, we didn't learn to hope for the audience to be in the character moving that was made by the operation which followed a physical simulation. Then, we got an idea when it was necessary to define the good character moving on the animation what we developed the anime creating system helped by the computer. In this paper, a technique of movement analysis of the animation is described.


Utilizing smart beamforming antennas in contention-based wireless mesh networks has proven to provide a significant increase in the network capacity. Nevertheless, their effectiveness in providing additional QoS guarantees is still under-explored. In this paper, we develop a framework for analyzing conflicts on wireless links considering both the physical interference and the operation of the underlying directional MAC protocol. Based on a novel taxonomy, we classify the link conflicts into several categories and propose a novel colored conflict graph abstraction to model the network interference pattern in the presence of contention-based directional MAC protocols. Using the proposed colored conflict graph, we derive a closed form expression for the probability of successful transmission over a wireless link given that all the bandwidth requirements are satisfied. Based on our analysis, we formulate the bandwidth-guaranteed routing problem as an optimization problem. Since the problem is NP-hard, we present a heuristic algorithm for joint routing and admission control to find single-path bandwidth-guaranteed routes. Using extensive simulations, we demonstrate the accuracy of our conflict analysis and the ability of the proposed algorithm to provide QoS guarantees along with efficient channel utilization.


Vehicle routing problem is a NP hard problem. To solve the premature convergence problem of the particle swarm optimization, an improved particle swarm optimization method was proposed. In the first place, introducing the neighborhood topology, defining two new concepts lepton and hadron. Lepton are particles within the scope of neighborhood, which have weak interaction between each other, so they update speed and position according to the individual extreme value. Hardon are the local optimal particles, which through collide to produce strong reaction, so set the local optimal particles collision with the global optimal particle to update speed and position. Finally, when the algorithm step to stagnation, we take particle decay to increase the population diversity. Simulated experiments show that stagnation behavior of basic particle swarm optimization are avoided in improved particle swarm algorithm and a good ability of searching better solution in process of solving vehicle routing problem.


We introduce a general risk model for portfolios with delayed claims which is a natural extension of the classical Poisson model. We investigate ruin problems for different premium principles and provide approximations for the ruin probability. We conclude with some specific models, for example, for IBNR portfolios and portfolios where the pay-off process depends on the claim size.


Given $2n$ points in the plane, it is well-known that there always exists a perfect straight-line non-crossing matching. We show that it is $NP$-complete to decide if a partial matching can be augmented to a perfect one, via a reduction from 1-in-3-SAT. This result also holds for bichromatic matchings.


Plant cells react to different environmental stimuli in different ways. The plant growth regulator abscisic acid (ABA) has been reported to be produced and involved in stress responses. To understand the role of ABA in relation to stress responses, we chose the ABA-induced RAB (responsive to ABA) gene as a marker to study both dehydration and osmotic-induced stress responses in rice cell suspensions. The kinetics of RAB gene expression under ABA, dehydration and mannitol treatments were studied. Dehydration-induced RAB expression was slower as compared to both ABA- and mannitol-induced RAB gene expression. Under dehydration conditions, the expression of RAB gene was correlated with an increase in endogenous ABA levels. Inhibition of protein or ABA synthesis prevented RAB expression under dehydration treatment. Under mannitol treatment, the RAB mRNA accumulated as fast as with ABA treatment, though there was no endogenous ABA accumulation. Inhibition of protein synthesis had no effect on mannitol-induced RAB gene expression. Proton pump inhibitor, calcium channel and outward rectifying potassium channel blockers reduced both dehydration- and mannitol-induced RAB gene expression. The potassium channel blocker BaCl2 reduced mannitol-induced RAB gene expression while it had no effect on dehydration-induced RAB gene expression. The possible differences in signal transduction between dehydration and osmotic stress are discussed.


Based on analysis at black soil region in southeast side of Daxing'anling area,the results show that forest has the effects of decreasing flood peak,reducing flood discharge and delaying the flood process to an isolated flood.In general,the runoff of dry season is larger in high forest coverage area than in the low area,and the annual distribution is more uniform in high forest coverage area.The annual runoff will reduce after deforestation,and it increases with the more forest coverage.


was quoting or echoing an O.T. prophecy when He said, ' They shall never perish, and no one shall snatcll (ap~ra~ec) tlzem out of my hand. l~Iy Father, which hath given them unto me, is greater than all ; and no one is able to snatch (áp7rá.'wl) out of my Fatlzer's hand. I and my Father are one' (Jn 1028-3°). It seems clear, however, that our Lord must have been referring definitely to Is 43 13. ' Yea, from everlasting I am He, and there is none that can deliver (lit. snatcla) out of my hand' (S~~t.) 1~'f~ IINI). S~~i1, which is one of the many words for ' deliver' in Hebrew, has the particular significance of 'pull away ' or 'snatch.'


M-SHRSP, a rat strain considered as a suitable model for the study of juvenile human malignant hypertension, were subjected to a variety of treatments for hypertension. The results showed the following: 1) It should be possible, through suitable diets appropriately combined with the administration of a selection of anti-hypertensive agents involving different mechanisms, to develop marked preventive and therapeutic results even for extremely malignant hypertensive rats such as M-SHRSP. 2) SQ 29852 seems to be a better drug than captopril. 3) In malignant hypertension, factors other than the high blood pressure itself, also, seem to play a role in the occurrence of such vascular lesions as angionecrosis.


The author describes software reliability and especially discusses several software reliability models,including Halstead model,Jelinski Moranda model,Little wood-Verrall model,Cai fuzzy growth model,Goel Okumoto NHPP model and the hypergeonetric distribution model.Finally,major problems currently faced for the field of software reliability are discussed.


The friction and wear behaviors of (Ca, Mg)-Sialon/GCr15 steel couple lubricated by alcohols such as 1-propanol 1-butanol 1-hexanol 1-octanol and 1-decanol were investigated by SRV friction and weax tester in a ball-on-disk configuration. It was found that, as compared with dry sliding, all the alcohols not only reduced the friction coefficient of (Ca, Mg)-Sialon sliding against GCr15 steel significantly but also reduced the wear volume of (Ca, Mg)-Sialon considerably (1-2order). Results of Fourier transform infrared spectroscopic (FT-IR) and GPC analyses showed that tribochemical reaction between (Ca, Mg)-Sialon and alcohols was involved in the friction process. The formation of Si-O-Si, Si-C and Si-O-C based friction-polymer on the rubbed surfaces is attributed to the excellent friction and wear reduction of alcohols. The lubrication mechanism of alcohols was propounded according to the experimental results and the references.


Compared with the polarized absorption of ND:YVO4 and the polarization of the LD(laser diode),high-efficient self-focusing lens coupling system was designed.Based on type II phase matching of the KTP crystal and the laser resonator which comprised with laser crystal and KTP crystal,calculating and analyzing the speciality of the plane-plane resonator with the existence of a thermal lens,a kind of high-efficient compact structure of the all-solid——state green laser was researched.Controlling the temperatures of the laser crystal and the KTP crystal accurately,when the pumping power is up to 4.8W,TEM00,mode green laser at 532nm of 1.4W is obtained with injection power of 4.8W,and optical-optical conversion efficiency of 30%.the instability less than 2%during 24 hours work.


It has long been recognized that tidal interaction between the components of close binaries will tend to circularize their orbits (e.g., Darwin 1879; Zahn 1977). In fact observations show an abundance of circular orbits in binaries with periods of days. However, the dissipation mechanism required for circularization, the timescales involved, and the dependence on period, mass, evolutionary state, and initial eccentricity of the system remain subjects of debate. Circularization theories such as Zahn (1977) state that circularization in binaries where at least one component possesses a convective envelope is much more efficient than in binaries where both stars have radiative envelopes. Giuiricin et al . (1984; GMM) studied the period-eccentricity distribution of O-, B- and A-type binaries and argued that the observations were consistent with Zahn's theory for radiative envelopes. But recently, Tassoul (1988) has presented an alternative circularization theory with similarly efficient circularization in radiative- and convective-envelope binaries. In addition, period-eccentricity distributions for many samples of main-sequence convective-envelope binaries are now available. Here we reconsider the observed short-period eccentricity distribution of radiative-envelope binaries in light of these new observations and theory. Specifically, we investigate the period-eccentricity distribution of a sample of binaries with A-type primary stars.


Responses: Overseas responses came from: (numbers in parenth ses indicate more than on response from a country). Argenti a (2), Australia (3), Bangladesh (2), Belgium (6), Brazil (4), Canada (7), Colombia (2), Costa Rica (2), Denmark (2), Egypt, El Salvador, Finland, France (7), Germany (9), Greece (3), Hong-Kong (2), I ia, Indonesia, Italy (5), Jamaica, Japan (6), Malaysia (3), Mexico (3), Netherlands (6), New Zealand (3), Nigeria (2), Norway, Peru, Philippines (3), Portugal, Puerto Rico ( ), South Africa (4), Spain (2), Sri Lanka, Sweden, Switzerland (2), Taiwan (3), Thailand (4), Tur ey, United Kingdom (5), Venezuela, Zambia, Zimbabwe (2), Si gapore (3). Informa ion Ob ai ed Information used in this article was obtained from the


A - Introduction: key concepts in stylistics 1 What is stylistics? 2 Stylistics and levels of language 3 Grammar and style 4 Rhythm and metre 5 Narrative stylistics 6 Style as choice 7 Style and point of view 8 Representing speech and thought 9 Dialogue and discourse 10 Cognitive stylistics 11 Metaphor and metonymy 12 New directions in stylistics: corpus approaches B - Development: doing stylistics 1 Developments in stylistics. 2 Levels of language at work: an example from poetry 3 Sentence styles: development and illustration 4 Interpreting patterns of sound 5 Developments in structural narratology 6 Style and transitivity 7 Approaches to point of view 8 Techniques of speech and thought presentation 9 Dialogue in drama 10 Developments in cognitive stylistics 11 Styles of metaphor 12 Developments in corpus stylistics C - Exploration: investigating style 1 Is there a "literary language"? 2 Style, register and dialect 3 Grammar and genre: a short study in Imagism 4 Styles in a single poem: an exploration 5 A sociolinguistic model of narrative 6 Transitivity, characterisation and literary genre 7 Exploring point of view in narrative fiction 8 A workshop on speech and thought presentation 9 Exploring dialogue 10 Cognitive stylistics at work 11 Exploring metaphors in different kinds of texts 12 Using corpora in stylistic analysis D- Extension: readings in stylistics. 1 Stylistics and the teaching of literature (Henry Widdowson) 2 Style and verbal play (Katie Wales) 3 Teaching grammar and style (Ronald Carter) 4 Sound, style and onomatopoeia (Derek Attridge) 5 A typology of narrative gaps (Donald Hardy) 6 Transitivity at work (Deirdre Burton) 7 Style variation and point of view (Mick Short) 8 The effects of free indirect discourse (Joe Bray) 9 Multi-modal analysis and the stylistics of drama (Dan McIntyre) 10 Conceptual blending and stylistic analysis (Barbara Dancygier) 11 Cognitive stylistics and the theory of metaphor (Peter Stockwell) 12 Corpus stylistics (Michaela Mahlberg and Catherine Smith)


Do embryo quality and morphokinetic behavior differ in the four groups of low-prognosis women as stratified by the POSEIDON criteria?

 Embryo quality and morphokinetic behavior differ across the POSEIDON groups, being more favorable in POSEIDON group 1, as well as were implantation and miscarriage rates.

 Poor ovarian responders (POR) represent 9-24% of patients undergoing ovarian stimulation, and the clinical management of these patients remains a challenge in everyday practice. In an attempt to standardize the diagnosis of POR, the medical community developed the Bologna Criteria and then shifted to the Patient-Oriented Strategies Encompassing IndividualizeD Oocyte Number (POSEIDON). Embryo monitoring with timelapse imaging (TLI) may allow the identification of morphokinetic events potentially affected by ovarian response. The aim of this study was to compare embryo quality, and speed and pattern of cell divisions in the four groups of POR as stratified by the POSEIDON criteria.

 This cohort study included low-prognosis patients undergoing their first intracytoplasmic sperm injection (ICSI) from Mar/2019 to Apr/2022 at a private-university affiliated IVF center, who met the POSEIDON criteria. A total of 3326 injected oocytes from 846 women were analyzed. Kinetic markers from the point of insemination were recorded. Generalized mixed models followed by Bonferroni post hoc were used to compare morphokinetics among the POSEIDON groups. The post hoc achieved power was > 80%.

 Injected oocytes were cultured in the EmbryoScope+ incubator, which recorded the following kinetic markers: timing to pronuclei appearance and fading (tPNa and tPNf), two (t2), three (t3), four (t4), five (t5), six (t6), seven (t7), and eight cells (t8), morulae (tM), start of blastulation (tSB) and blastulation (tB). Durations of second and third cell cycles (cc2 and cc3) and timing to complete synchronous divisions s1, s2, and s3 were calculated. The KIDScore ranking was recorded.

 The results from the generalized mixed models followed by Bonferroni post hoc for the comparison of means among groups showed that embryos derived from patients in the POSEIDON groups 2, 3 and 4 showed significantly slower divisions compared to those from POSEIDON 1 group (Table 1). The KIDScore rank was significantly lower for embryos derived from POSEIDON groups 2, 3 and 4 (2: 4.4 ± 0.7 vs. 3: 4.2 ± 0.2 vs. 4: 3.0 ± 0.4) compared to those derived from POSEIDON 1 group (4.8 ± 0.1, p < 0.001). Group POSEIDON 1 also showed improved implantation (26.9% vs. 2: 22.4% vs. 3: 20.0% vs. 4: 14.0, p < 0.001) and miscarriage rates (5.6% vs. 2: 31.2% vs. 4: 50.0%, p = 0.013).

 The use of historical cohort groups is a drawback. Despite the eligibility criteria for inclusion in the analysis, potential differences in the baseline characteristics cannot be ruled out.

 Embryo development was more favorable in POSEIDON group 1, suggesting a direct relationship between oocyte quantity and quality, and that oocyte quality is determinant of embryo development. These show the reasonability of classifying POR by the POSEIDON criteria, providing information for the appropriate counselling of POR regarding their possible prognosis.

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War and neutrality — War in general — Effects of outbreak of war — On treaties — Extent to which declaration of war terminates international conventions as between parties to hostilities — Requirement that hostilities render observance permanently impossible The law of Italy Treaties — Termination of — By operation of law — Outbreak of war — Extent to which declaration of war terminates international conventions as between parties to hostilities — Requirement that hostilities render observance permanently impossible — Geneva Convention on Commercial Arbitration Clauses, 1923 — The law of Italy


: Starting from ephemeris data (including positions and velocities) for any solar system planet, this software calculates the planetary orbital angular momentum (with respect to inertial frames) and its time derivative d L /dt . The latter is then employed to obtain the torque on the chosen subject body arising due to orbit-spin coupling, as derived and described in [Shirley, J. H., Planetary & Space Science 141, 1-16]. The software described here, which is written in the IDL programming language, performs a series of coordinate transformations on the astronomical vector data. These are required in order to resolve the time-varying accelerations applied to discrete parcels (or volumes, or particles) of an atmosphere, as a result of the torque, over the time period covered by the ephemeris data supplied. The end user will typically have a pre-defined, gridded system of locations (latitude, longitude, altitude or radius vector) specific to his or her own application. The final step, to be performed by the end user, is to propagate the forcing accelerations to all grid points within the atmospheric circulation model, thereafter repeating this operation for all time steps of the simulation.


The authors explore the influence of academic major and cocurricular leadership activities on students' ability to make mature career choices.


In autumn 2010 the first findings of the North American leafhopper Erasmoneura vulnerata (Fitch, 1851) were recorded in Slovenia. Fairly large populations were observed in various localities around Nova Gorica especially on Vitis labrusca 'Isabella' and Cercis siliquastrum. Short description of the species and its biology are given.


A formal model of the process concept is presented. This model can represent sets of processes that use the synchronization primitive PV or one of the many generalizations of PV. The study of synchronization problems is then reduced to the study of relations between sets of processes. For one relation— "simulate"—it is possible to show that there are differences between several synchronization primitives. These differences show that the relative "power" of these synchronization primitives is not the same.


e21037 Background: There are many drugs that can be applied to the treatment of lung cancer. These therapeutics include classical chemotherapeutics, targeted drugs against driver mutations, and immunotherapeutics. However, still, new agents are required to better results and patients outcomes. Recently, imidazole and its compounds, a type of antifungal drugs, were found to have antitumor efficacy in several cancer types. Its effects on non-small-cell lung cancer cells are yet known. This study aimed to detect anti-cancer properties of imidazole on non-small-cell lung cancer cells and suitability for clinical usage as an anti-cancer agent. Methods: We used A549 cell lines that are non-small-cell lung cancer cells in this study. A549 cells were treated with imidazole (molecular grade) at 1, 5, 10, 20, 40, 80 mM doses for 24, 48 and 72 hours. Cytotoxicity and IC50 values (the half-maximal inhibitory concentration) were calculated using MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) analysis. Colony formation assay was performed to detect the effect of imidazole on cancer cell colony formation ability. The cellular morphological alterations were observed on bright-field microscopy using Giemsa staining. Cellular migration status of A549 cells was defined with in vitro scratch assay up to 48th hour. Results: Cytotoxicity assay results showed that low-level imidazole induced cell proliferation. However, high-level imidazole treatment decreased the cell viability of A549 cells in a dose and time-dependent manner. The IC50 value was calculated as 60 mM, 28 mM, and 15,9 µM doses respectively at 24, 48, 72 hours in A549 cells. Also, we determined that the number of colonies (number of colonies: 42.7 ± 3.06) formed in A549 cell lines treated with imidazole at IC50 dose was statistically less than the colony number of the control group (number of colonies: 70.7 ± 5.13) (p < 0.01). Interestingly, we observed that colony number increased at a low dose (at 5 mM) imidazole treated group, statistically significant (p < 0.05). Cellular morphology was not affected at low doses; however, at the IC50 dose, A549 cells changed their cellular morphology, lost cell-cell contact, decreased cytoplasmic volume, and differentiated from parental morphology. In addition to these effects, we observed that imidazole treated cells decreased their migration capabilities compared with control group cells (p < 0.05). Conclusions: Our results have shown that antifungal imidazole treatment inhibits cancer cell biological responses such as proliferation, colony formation ability, and motility in non-small lung cancer cell lines in a dose and time-dependent manner. These results suggest that imidazole would be the right candidate for the synergy with other therapeutic options such as immunotherapy. This introductory study allows us further studies exploring the synergy and its mechanism.


General-purpose audio tagging refers to classifying sounds that are
of a diverse nature, and is relevant in many applications where
domain-specific information cannot be exploited. The DCASE 2018
challenge introduces Task 2 for this very problem. In this task, there
are a large number of classes and the audio clips vary in duration.
Moreover, a subset of the labels are noisy. In this paper, we propose
a system to address these challenges. The basis of our system is
an ensemble of convolutional neural networks trained on log-scaled
mel spectrograms. We use preprocessing and data augmentation
methods to improve the performance further. To reduce the effects
of label noise, two techniques are proposed: loss function weighting
and pseudo-labeling. Experiments on the private test set of this task
show that our system achieves state-of-the-art performance with a
mean average precision score of 0.951


The analysis of interconnects in the presence of incident electromagnetic fields is an important part of the design process. Such an analysis is, however, very CPU expensive due to the large size of interconnects networks. Krylov based reduction methods were proposed in order to address the complexity of such simulations, however, they result in macromodels which are not optimal and still contain many redundant poles. In this paper a two level reduction method is proposed for interconnect affected by incident electromagnetic fields. The macro-models obtained using the proposed approach is less than half the size of those generated by previous techniques. The first level of reduction is a conventional Krylov subspace based reduction, while the second level is based on singular value decomposition. Furthermore, the proposed method is a projection method based on congruence transformation and is therefore passive by construction. Numerical examples are shown in order to illustrate the accuracy and efficiency of the proposed technique


The present era, marked by many crises in human affairs, will doubtless take its place in history as a singularly parlous period. The world has witnessed two major wars and many minor conflicts in the first two-thirds of the twentieth century. Their violence with the attendant toll in life and suffering has not only dislocated the economic and physical welfare of virtually all nations, but has left a heritage of suspicion and deep-rooted hostility that ranges from continued cold warfare to actual combat in a number of quarters of the globe. The population explosion has lent added substance to nationalistic fears and protective designs. To compound the sense of insecurity in a period of unheralded affluence, this country is faced by a ground swell of unrest that has invaded even the sanctuary of our institutions of higher learning. These conditions obtain in the face of scientific advances that transcend the wildest dreams of a generation past. Man has explored the depths of the fathomless seas and the vast reaches of the boundless skies. The astronauts have extended the frontiers of


Thirty‐nine primary surgical cases for correction of congenital aural atresia were reviewed for complications and long‐term hearing results. Hearing averages of 25 dB for mild atresia, 40 dB for moderate atresia, and 46 dB for severe atresia were obtained. Serviceable hearing was achieved in 64% of the cases. The two most frequent complications were stenosis and recurrent infections of the cavity and canal skin, with an incidence of 33% and 31%, respectively. Use of split‐thickness instead of full‐thickness skin graft was associated with fewer complications. The goal of this review is also to share the experience of the senior author in the management of this complex problem.


The study aimed to identify the role of the Jordanian family in moral education of its children from the perspective of parents', and find out the impact of the study variables; responder variables, parents' level of education, number of family members, housing and region on the family's role in the moral education of its children. The study adopted the descriptive developmental approach, and the sample of the study consists of (4000) fathers and mothers from the Jordanian society. A questionnaire was designed to identify the level of the family's role in the moral education of its children as perceived by the parents. The study instrument was applied to the study sample after verifying its validity and reliability.
The study results revealed that the overall mean of the level of the Jordanian family's role in the moral education of its children was large in all fields as the social values field came first, followed by the field of economic values, the field of the protective role, the field of the therapeutic role, the intellectual field, the developmental field and the aesthetic field, respectively.
The results of the second question showed that there are statistically significant differences in the family's role in the moral education according to the respondent variable, and the differences appeared in the fields of the family's developmental role, the therapeutic role, intellectual values, and aesthetic values. The differences were in favor of the fathers. The results also indicated that there are statistically significant differences in the tool of the family's moral educational role according to the variables of the educational level, income level, number of children, place of residence and region. The differences appeared in all fields of the instrument.


the consumer is the identity central to the consolidation of market governance in the New Zealand telecommunications industry. This identity is usually unequivocally associated with the enterprising and individualistic self of neo-liberalism. In this form of self the economic and social are cast as antagonistic, part of the process recently described as the 'de-socialization' of economic governance. This paper claims that the legacy of post-war retionalities, in which the citizen was cast as a social being, could not be so easily negated. Mobilizing the identity of the consumer necessarily involved attempts to reforge the links between the economic and social. Rather than marking the 'death of the social', the emergence of the consumer involved the mutation of the social into new forms. Two different versions of the consumer are identified. In the first version the economic and the social are recombined in this identified. Attemps are made to constitute the consumer as an inclusive identity encompassing a...


We will get by, we will get by, we will get by, we will survive. —The Grateful Dead, "Touch of Grey" …somehow in the streets of London, on the ebb and flow of things, here, there, she survived, Peter survived, lived in each other, she being part, she was positive, of the trees at home; of the house there, ugly, rambling all to bits and pieces as it was; part of people she had never met; being laid out like a mist between the people she knew best, who lifted her on their branches as she had seen the trees lift the mist, but it spread ever so far, her life, herself. —Virginia Woolf, Mrs Dalloway The first headnote, clearly, puns on the prefix "bi" in the title. The "by" in "Touch of Grey" is linked to survival—we will get by, as the Grateful Dead repeat, and add, as an almost redundant coda, we will survive. In Mrs Dalloway the freefloating narrator links survival—but after death, not in life—to trees. It is through our tree-like linkage—our branching out—to other people that we survive. Trees are, or can be, a lattice, a network. Woolf here suggests that our survival is dependent on this kind of network. It is not just through a one-on-one, binary connection, that we continue on after death, but rather through a mesh of multiple connections. And the Grateful Dead acknowledge this multiple dimension of survival too. The refrain beginning "We will get by" is repeated throughout the song as "I will get by"; the first-person pronoun changes to "we" only in the very last line of the song. This notion of survival through a complex system is an integral part of Darwinism. Darwin's emphasis on an "inextricable web of affinities" (Darwin 415) is highlighted now by many scientists who hope to suggest the complexities of evolution through the use of the term "coevolution." Coevolution is conceived of in multiple ways, but for the sake of this essay I will define it as the way "two interacting species or groups of species change in response to each other" (Vermeij 219). Coevolutionary approaches, as the sociologist Myra Hird writes, "consider selective pressures as more involved with each other, more enmeshed" (740).


Sustainability manufacturing practices like lean and green manufacturing seek to optimize production efficiency while minimizing environmental impact and maintaining social equity. It is also well knowing fact that company that adopt sustainable practices are able to achieve better quality, improved productivity and profitable growth. Among these lean is an important practice that leads us towards sustainability initiatives by eliminating waste at all levels in system and using the resources efficiently. In this paper an integrated lean sustainability development model has been proposed to integrate supplier, organization and customer.


A Digital-to-Analog Converter (ADC) converts various forms of communication in the real world to portable digital integers. ADCs play a vital role as it interfaces between the analog world and digital world. Wireless sensor networks and biomedical interfaces are common examples of applications that demand ultra-low power consumption in the ADC. This research paper shows reduction in the energy consumption of an ADC used in neurostimulator which stimulates the brain for the people suffering from various disorders which includes Tumours, Parkinson's disease, Obsessive Compulsive Disorder (OCD), Epilepsy, and many more. The simulation is carried out by Cadence Virtuoso tool using various technologies.


Unfinished Business'. II Last month I discussed the tasks that lie ahead in formulating and adopting a realistic set of goals for ACM. In this letter, I wish to share with you my views on where we are with respect to the management of ACM and what still remains to be done. I urge every voting member to consider my remarks carefully and to vote in next month's election. There are many elements to the management of a technical society's affairs. However, I shall concentrate only on five major areas. Council. ACM policy and administration are vested in the Council. It serves both a legislative and a judicial function, and it is theoretically representative of the entire membership eligible to vote on ACM affairs. The methods employed in electing Regional Representatives to Council leave much room for improvement , but the process really becomes deficient when those elected accept the honor and prestige of winning as their personal due, but do not accept responsibility for running ACM or even for representing their regional constituents. There have been a few instances of this kind recently, and the question of whether the structure of Council should be revised has been raised. Council meetings have the flavor of a faculty senate rather than that of 209 a board of directors. Bernie Galler recognized this and during his term as president took major strides toward the board-of-directors mode of operation. I have tried a few additional innovations in an attempt to move farther in this direction, but the Council meetings still suffer from a basic attitude that anyone elected to Council should have the right to nitpick on any agenda topic-whether he has experience in that particular subject matter or not, and whether his facts are correct or not. I believe your next president will have a more difficult time than he deserves because the elimination of the faculty senate mode of nitpicking in Council is incomplete. Executive Committee. The ACM Executive Committee is an anachronism. Composed solely of the three elected officers, it is not large enough to perform the traditional role of handling duties assigned to it between Council meetings. Furthermore , in trying to perform an executive function and in delegating responsibilities , the Executive Committee is often considered a competitor by Council rather than a servant. The intentions of those early ACM members who created the existing concept of the …


The element rhenium is known to form only one
extremely rare mineral dzhezkazganite. Much of
the rhenium in nature occurs in small quantities,
usually in the parts per million range substituting
for molybdenum which is a chemically
similar element. An investigation was carried out
to determine the amount of rhenium in some
molybdenites of Tasmanian origin.


Based on the visit and investigation in the laboratories of Korean University of Technology and some other universities,this paper analyzed their management methods and operation modes,and summarized their successful experiences.By means of contrast and analysis,it proposed the corresponding measures to improve the management efficiency of the laboratories of universities of our country.


This article study the performance of the bivariate dispersion control charts, namely the and the charts, for the bivariate normal, bivariate exponential, bivariate t(5), bivariate Logistic and bivariate Laplace distributions. The asymmetrical probability limits of these charts are proposed for the distributions under study. The estimated factors and quantile points used in the construction of these two charts are provided for the bivariate non-normal distributions. The effect of improper use of constants and quantile points in the construction of the and the charts are studied in terms of the associated false alarm rates. The performances of the proposed limits of the given charts are evaluated in terms of average run length for the various bivariate distributions and compared. The performances of these control charts are also compared with their respective 3σ limits.


The social skills deficit vulnerability model predicts that poor social skills minimize opportunities to acquire social support, in turn, leading to the proliferation of psychological distress. This prediction was tested in a 2-wave longitudinal study that assessed 211 emerging adults at Time 1 (T1), with a 70% response rate 1 year later at Time 2 (T2). The results indicated that, after controlling for psychological distress at T1, social skills at T1 had an indirect effect on lower psychological distress at T2, through higher social support. Thus, people with poor social skills may be vulnerable to the development of psychological distress because they have less access the protective effects of social support.


The present invention relates to an ultrasonic device for the rotation from the vascular system and method for generating an image as a whole. In ultrasound imaging, spatial resolution and penetration depth is an important parameter for the quantitative evaluation of image quality. Generally, the wavelength of the ultrasonic frequency center determines the spatial resolution, and the resolution is improved as the frequency increases. However, tissue attenuation typically increases as a linear function of frequency, and even at application becomes non-linear ultrasound imaging commonly used in higher frequencies (e.g., greater than 40MHz) in a blood vessel.


New rate-1/3; linear trellis (convolutional) codes with 8-PSK modulation for bandlimited additive white Gaussian noise channels are reported. The simulated bit error probability performance of the trellis-coded modulation schemes with unquantised Viterbi decoding shows useful coding gains over the uncoded coherent BPSK having the same bandwidth efficiency of 1 bit/s/Hz, and the schemes are suitable for use in many practical bandlimited channels.


Non‐small cell lung cancer (NSCLC) is the commonest malignancy with high death rate around the world. LncRNA metastasis‐associated lung adenocarcinoma transcript 1 (MALAT1) is greatly overexpressed in multifarious cancers, including NSCLC. However, the precise mechanism of MALAT1 in NSCLC tumorigenesis is blurry. This paper aims to investigate the theory of MALAT1 action in NSCLC progression. The levels of MALAT1, microRNA (miR)‐185‐5p, and mouse double minute 4 protein (MDM4) were measured by quantitative real‐time polymerase chain reaction (qRT‐PCR) or western blot. Cell proliferation and apoptosis were, respectively, determined by 3‐(4, 5‐dimethyl‐2‐thiazolyl)‐2, 5‐diphenyl‐2‐H‐tetrazolium bromide (MTT) assay, and flow cytometry. Cell migratory and invasive abilities were inspected by transwell assay. The binding relationship between miR‐185‐5p and MALAT1 or MDM4 was confirmed by dual‐luciferase reporter assay. The impacts of MALAT1 on tumor growth in vivo were measured by a xenograft experiment. We found MALAT1 and MDM4 were upregulated and MALAT1 positively regulated the MDM4 expression. MALAT1 and MDM4 deletion significantly hindered the proliferation, metastasis, and expedited the apoptosis of NSCLC cells. MDM4 overexpression partly overturned the influence of MALAT1 downregulation on cell development. Moreover, miR‐185‐5p, as a target of MALAT1, could directly target MDM4, and miR‐185‐5p upregulation exerted inhibitory effects on NSCLC cells. Besides, knockdown of MALAT1 inhibited tumor growth in vivo through miR‐185‐5p/MDM4 axis in NSCLC. Collectively, MALAT1 contributed to proliferation, migration, invasion, and impeded apoptosis by regulating the MDM4 expression mediated by miR‐185‐5p in NSCLC cells.


Abstract The effort–reward imbalance model (ERI; Siegrist, 1996) has been found to be a strong predictor of both psychological and physiological outcomes. Morningness–eveningness (M-E) is believed to relate to shift workers' ease of adjustment to irregular working patterns. However, it has not been investigated in conjunction with the ERI model. The present study (1) explored whether M-E acts as a predictor of psychological adjustment to shift work, above and beyond the contribution of the ERI model and (2) examined whether the formulation of the ERI model may be overly complex. A sample of police employees (N=112) completed a baseline questionnaire that contained the ERI model and a measure of M-E. Two months later, participants completed measures of work–family conflict and burnout. Regression analyses demonstrated that ERI was a significant predictor of psychological adjustment to shift work. Moreover, and for the first time, M-E was found to make a unique contribution to the prediction of work–family conflict, such that evening types reported greater levels of maladjustment. However, it did not make a unique contribution to the prediction of burnout. The possibility that the ERI model is unnecessarily complex received partial support, with the ratio score only contributing additional variance in one of four regressions. The results indicate that adjustment to shift work and attendant effects on work–family conflict can be affected by an individual's morning-evening typology.