Object To screen antifungal agents against Candida albicans (Robin) Berkh, Saccharomyces cerevisiac Hansen GL-7 and Prototheca wickerhamii from 164 traditional Chinese medicines (TCMs). Methods The extracts of 164 TCMs were prepared with 95% ethanol and the antifungal activity of these extracts against above three fungi was measured by semisolid agar dilution method. Results The ethanol extracts from 22 TCMs exhibited potent antifungal activity. Conclusion The antifunal activity of the ethanol extracts from TCMs was measured by using semisolid agar dilution method for the first time. The ethanol extracts from the bark of Pseudolarix kaempferi Gord. and Paeonia suffruticosa Andr. are more potent antifungal agents than those of tested other medicines.


OBJECTIVE
To examine the influence of the parent artery pathology on the local hemodynamics on the level of aneurysm.

MATERIAL AND METHODS
Mathematical models of the arteriovenous malformation (AVM) were built on the CT-angiography data of real patients. To simulate the thrombosis, the parent artery and its branches were sequentially turned off in the model 1. In the model 2, the simulation of embolization of AVM was achieved by cutting off the exactly section of the parent artery that was involved in the arteriovenous formation.

RESULTS AND CONCLUSION
Model 1 showed that the flow redistribution did not significantly impact on the risk of rupture after the parent artery was turned off and blood pressure was increased in both aneurysms by 3 mm Hg. Model 2, in which the aneurysms were combined with a direct arteriovenous drainage with low peripheral resistance, showed that turning off the parent artery and pathological drainage led to the serious reduction in the venous drainage flow and it's increasing in the parent artery by about 60% that significantly increased the risk of rupture.


The invention discloses a call hanging-up method and device. The method comprises the steps that when a mobile terminal receives a call hanging-up instruction and the mobile terminal determines to receive a voice signal within the preset time period after the mobile terminal is moved away from the ear of a user, the mobile terminal extracts voice frequency characteristics of the voice signal; the mobile terminal judges whether the voice frequency characteristics of the voice signal are matched with the voice frequency characteristics of a voice signal, received by the mobile terminal in the conversation process, of an opposite-end user or not; if yes, the mobile terminal gives a faulty hanging-up prompt to the user, and when a hanging-up canceling instruction is received, hanging-up of the conversation is refused; if not, the conversation is hung up. The call hanging-up method and device reduce the faulty call hanging-up probability.


The objective of this study was to assess the in vitro probiotic potential of Lactobacillus plantarum Lp10S and Lp11S isolated from Sha'a and evaluate their effects on lipid metabolism of hypercholesterolaemic rabbits. The strains were tested in vitro for their acid and bile tolerance, capability to remove cholesterol from MRS broth and to deconjugate bile salts. For in vivo studies, Lactobacillus plantarum Lp10S and Lp11S were administered to rabbits fed on cholesterol-enriched diet (standard diet+2×0.02 g of pure cholesterol per day per rabbit) at a dose of 2×10 8 CFU per day per rabbit for each strain; the treatment lasted seven weeks and one week post ingestion period was observed. Serum lipids were analyzed during the experiment. The results revealed that strains Lactobacillus plantarum Lp10S and Lp11S tolerated well low pH and bile salts, expressed bile salt hydrolase activity and have ability to assimilate cholesterol in vitro. The results also showed that diets including Lactobacillus plantarum Lp10S and Lp11S significantly lowered serum total cholesterol, (VLDL+IDL+LDL)-cholesterol and triglycerides levels of hypercholesterolaemic rabbits. In addition, HDL-cholesterol level significantly increased and the atherosclerosis index was significantly lowered. The present results indicate the probiotic potential of Lactobacillus plantarum Lp10S and Lp11S strains as well as their in vivo cholesterol-lowering properties that may be useful for their application as health-promoting bacteria.


Stamping process of motor stator rotor cores was analyzed,and the double nesting and no waste-free multi-position progressive die program was determined.The technologies of double precision bearing on strip,waste bounce detection, blanking workers dislocation row,tighten block correction were adopted.This solved the key issues of double row and no waste punching.The application shows that the die works stably,material utilization and production efficiency is improved, economic efficiency is increased.


Constitution Movement which generated in the 1930s have deep influence because of its particular political situation both foreign and domestic. At the same time it is a thin part of the research on Constitution Movement of China. This article will generate and analyze the requirement for Constitution Movement proposed by the intelligentsia of liberatism in this period. Furthermore, it will explore how the intelligentsia of liberalism influence and push forward the Constitution Movement.


The principle of Ether network and CobraNet for transmiting digital is explained. The structures of traditional and high speed Ethernet, the transmission control protocal and interconnection of network are analyzed. The features of professional CobraNet and structure of MAC(Media Access Control) is introduced.


We consider the $f(R,T)$ modified theory of gravity, in which the gravitational Lagrangian is given by an arbitrary function of the Ricci scalar and the trace of the energy-momentum tensor of the matter, in order to investigate the dark-matter effects on the galaxy scale. We obtain the metric components for a spherically symmetric and static spacetime in the vicinity of general relativity solutions. However, we concentrate on a specific model of the theory where the matter is minimally coupled to the geometry, and derive the metric components in the galactic halo. Then, we fix the components by the rotational velocities of the galaxies for the model, and show that the mass corresponding to the interaction term (which appears in the Einstein modified field equation) leads to a flat rotation curve in the halo of galaxies. In addition, for the proposed model, the light-deflection angle has been derived and drawn using some observed data.


We report stationary fluorescence, fluorescence excitation spectra, site-selective fluorescence spectra, and femtosecond time-resolved fluorescence spectra of vacuum-evaporated α- quaterthiophene (T4) and α-quinquethiophene (T5) polycrystalline thin films at various temperatures. It is found that the fluorescence spectrum of each compound studied is a superposition of emission spectra originated from energetically and spatially separated fluorescent species or sites, which are suggested to be disordered-molecules, pre-aggregates, aggregates, and physical defects. The disordered molecules lying at grain boundaries display a solutionlike fluorescence decay feature. Multiple fluorescence spectra with identical vibrational developments from pre-aggregate species are observed in the T5 film. A long-lived fluorescence decay component observed in the T4 film is attributed to the dipole-allowed transition in the aggregates. A slow rise observed in the time-resolved fluorescence of the T4 film is interpreted in te...


Surface defects detection techniques are widely used and play very important roles in many fields, such as precision optical element used in high energy laser, wafer used in semiconductor, cover glass used in mobile phone, etc. This paper introduced the research progress in surface defect detection based on vision measurement, analyzed the significant and application of detecting the surface defect by using vision measurement, summarized the main work of this technology, and analyzed the key points and challenges in the application of these techniques. At last, this paper outlines the prospect and the direction for the surface defect detection based on vision measurement.


In the business or enterprise classroom, industry engagement within the curriculum can provide opportunities for students to gain a professional network, an understanding of the world of work, and to develop their mastery of business concepts. This article presents a case for educators to foster collaboration with external stakeholders in the assessment of undergraduate students. To increase purposeful industry involvement in a large university module of enterprise education, an innovative showcase assessment method was developed and implemented. Leveraging the power of a large class cohort, business professionals and university staff were invited to contribute to student assessment at a poster showcase that was run to scale. Through careful planning, this instructional innovation allowed a large student body (450-500 students) to have direct contact with industry representatives, while retaining standards of care and grading legitimacy. The authors describe and analyse this innovation, share challenges faced, and offer suggestions for application in future or remote (virtual) settings. A number of recommendations for the logistical and scholarly application of such a method are provided, to aid educators aiming to replicate such a pedagogical technique.


Analysis of the historical development of medicine and pharmacy in the Middle Volga region in XVI - XVIII centuries is of undoubted interest. During this period, the supply of medicine to the population was carried out mainly through herbal shops and trading rows [1-3, 7], which led to the abuse of potent and poisonous medicines. The use of local resources was extremely insignificant, medicines were mainly imported from abroad - from the West by healers, from the East by merchants (cinquefoil, rhubarb, camphor, musk, cloves, almonds, chilibukha).


An inner ring 10 of a constant velocity universal joint includes ball tracks 12 formed in an outer surface 14 at predetermined intervals in a circumferential direction. Portions of side walls of the ball tracks 12 that form edge lines with the outer surface 14 are formed with a chamfer 16 along the entire length of the axial direction.


The aim of the thesis is to familiarize the reader with the issue of pragmatic presupposition, whose great pioneer has been the American philosopher Robert C. Stalnaker. His appearance at the beginning of the 70s of the 20th century brings in a radically fresh viewpoint and widens its applications onto the field significantly overlapping all the previous research. Our explication emphasizes the interconnection of the issue with the question of the interface between semantics and pragmatics. The peak of the thesis is in connection to this emphasis the introduction of Stalnaker's context description, which already lies in the terms of pragmatic presupposition.


One of the application of the second stage of next generation passive optical network (NG-PON2) based on time and wavelength division multiplexed PON (TWDM-PON) is expected to be fronthaul streams in fifth generation (5G) mobile networks. TWDM-PON has ability to transfer up to 40 Gbps and can be coexistence with previous time division multiplexed TDMPON generations without any change to optical distribution network (ODN). In this paper, we demonstrate a software defined (SD) dynamic bandwidth wavelength allocation (DBWA) mechanism in converged mobile and TWDM-EPON architecture. In the proposed mechanism, the multi-scheduling domain (MSD) is used to separate the bandwidth allocation between hybrid remote radio network unit/optical network unit (RRU/ONU) and conventional ONU into virtual groups (VGs). When the current wavelength in certain VG is overloaded, the optical line terminal (OLT) automatically distributes to the other wavelengths in the others VGs. Simulation results show that our proposed mechanism is able to maintain the overall quality of services (QoS) system performance in terms of mean packet delay and EF jitter.


Driver Assistance System (DAS) is one of the most mandatory subsystems of Intelligent Transport System (ITS). Speed Bump Detection (SBD) is a subset of DAS that supports the driver to recognise the presence of speed bump and alert the driver. Under the critical condition, it has to operate on the vehicle directly for safety. In the research work, two methods of Speed Bump Detection have proposed (i) Otsu's threshold method and (ii) Morphological Operation method. These methods are superior to the existing methods because it does not involve any network, so it is free from GPS error, network overload, delay and false alarm. It also detects the speed bump with low projected where the existing method using sensors fails. The proposed Otsu's method is straight forward, efficient and gives 74.6% accuracy for all types of road condition. The performance of Morphological or structural operation method achieves better result 85.8 % detection ratio. The two proposed methods give more than 90 % detection ratio for properly painted road and optical illusion type speed bump.


AIM
Our objective was to compare the diffusion properties of brain metastases as imaging biomarkers in various types of tumours, to determine their histology and origin.

MATERIAL AND METHODS
Magnetic Resonance Imaging (MRI) and diffusion-weighted imaging (DWI) were used to retrospectively study the data of 143 patients suffering from brain metastases. Four categories of primary tumours with metastases to the brain were included: lung carcinoma (n = 102, 71.3%); breast carcinoma (n = 27, 18.8%); colon carcinoma (n = 8, 5.6%); and others (n = 6, 4.2%). The Apparent Diffusion Coefficient (ADCmin ) values, as well as the normalised ADC ratio (nADC), were determined. The lesions on the DWI were categorised as follows: type 1, with negative findings on DWI; type 2, which were isointense with the normal cortical grey matter; type 3, which were hyperintense compared to the normal cortical grey matter.

RESULTS
The diffusion type, mean ADCmin, and mean nADC showed statistically significant differences in different types of metastases. In the subgroup analysis, it was found that type 3 was the diffusion type found most extensively in the brain metastases of small cell carcinoma (SCLC) (n = 52, 65.8%, p 0.000). Furthermore, the mean ADCmin and nADC values were the least for the brain metastases of the SCLC (552.0 ± 134.2 and nADC = 0.8 ± 0.1, p 0.000, respectively). The value of the mean ADCmin was low in the human epidermal growth factor receptor 2 (HER-2) negative groups than in the HER-2 positive groups at 786.8 ± 299.1 vs 844.8 ± 141.3 (p 0.006).

CONCLUSION
Our findings indicated that there is a correlation between diffusion parameters as imaging biomarkers of the solid component of brain metastases of primary tumours and the tumour histology.


The German"dual system" vocational education mode is advocated in our country, the Sino German occupation education cooperation has become the "benchmarking" of the foreign cooperation in the China. Vocational education of Xinjiang Sino German cooperation is still in the trial stage. This paper takes Xinjiang Vocational University's cooperation with the German school as an example, the analysis of adaptability of Xinjiang and German's cooperation about occupational education, so as to benefit the further development of cooperation on Xinjiang occupation education.


Abstract During the past decade or so, this late-modern society in which we, in the West, live has frequently been called a learning society; it is also one which is materialistic with its pre-eminent knowledge base being scientific. Indeed, the humanities appear to be of less significance and theology is no longer the queen of the sciences, even the institutional practice of religion appears to be declining. Consequently, the churches are confronted with an outreach issue of quite major proportions and the question that I want to explore in this paper is whether the churches' mission should be educational or evangelical in this learning society. In order to do this, I want to explore in three parts the processes of human learning—which I will argue are existential, then the relationship between the churches and religious education, finally, I will focus on the nature of education and truth and I will then draw out the implications of my argument.


In this paper we describe the main features of the mark-up language developed by the Text Encoding Initiative (TEI), now the standard protocol for digitally encoding all types of text structure, from novels and plays to poetry, speeches and scientific articles. We examine different areas of application and look at examples of digital humanities projects and online heritage collections that use TEI.


Parallel Machines: Organizing Higher Order Functions for Parallel Program Derivation John O'Donnell and Gudula Rnger University of Glasgow, UK, and Universitt Saarbrcken, Germany We need to take a flexible approach in designing a family of higher order functions to support parallel program derivation. For example, it isn't enough just to define scan and give it a log time cost model, because there are actually many different implementations with different costs, suitable in different circumstances. To help a programmer decide what to do next in a derivation, the parallel operations need to be defined at several levels of abstraction and to have a suitable operational semantics at each level. We propose Abstract Parallel Machines to address these problems, and we apply them to two case study derivations: a parallel heat equation program and a parallel addition algorithm. An abstract parallel machine defines a set of parallel operations, and it expresses these definitions using a set of computational sites ("abstract processors") and coordination functions ("abstract network"). This makes a suitable model of implementation available at each level. The framework can describe higher order parallel operations at high levels (SPMD), intermediate levels (scan) and low levels (digital circuits). We have found that this approach helps guide the derivation process by clarifying the relationships between alternative realizations of a function, and we plan to experiment with it on more complex case studies. Costs, Transformations, and Parallel Programming David Skillicorn Queen's University at Kingston, Canada A programming model cannot be useful for designing programs unless it possesses a transformation system. A transformation system is not useful unless it possesses a cost model. A cost model maps functions to program texts (that is, implicit implementations) and transformation rules to rewrite rules. It is useful to consider what we might expect of a cost-based transformation system. There are two properties of interest. The first is the degree of confluence.


We describe an approach to developing a mathematical model of color harmony. This will be applied in the color harmonizer, an automated tool for coloring computer interfaces and Web sites. The tool will incorporate a color harmony engine that can incorporate a variety of theories for color harmony, and in the first instance, will use the rules proposed by Munsell and adapted to use in computer displays. We describe abstract and concrete color schemes, the Chromotome (a tool developed to facilitate the selection of colors) and techniques for grouping interface elements.


Abstract Accurate measurements of the viscosity of Hg-In amalgams have been carried out using an oscillating viscometer and their interpretation is briefly discussed.


The formula of reaction exothermic rate P_(rea) of sensors and the differential equation of closed test chamber gas concentration C varies with t is given.From the solution of differential equation C-t curve,it is proved that the relaxation of gas concentration is rather slow and the errors of clssed chember test can be neglected.


this article studies the influence of simultaneous operation between a converter for charging Li – Ion batteries and a converter for active voltage balancing (active BMS). The voltage equalization system consists of resonant inverters with synchronous voltage doubler rectifier (SVDR) connected to their outputs. This system is applicable for batteries made of either Li – Ion cells or supercapacitor cells. Simulation model has been developed for analysis of the converters. The results are confirmed by an experimental stand.


We investigated mumps virus (MuV) strain differences following infection of distinct human cell types chosen as the representative targets during natural infection. Intent was to examine the ability of MuV strains (vaccine and wild-type) to trigger an innate immune response in these cells by comparing induction of viral RNA sensors and selected components in type I IFN induction cascade. The cell monolayers (A549, SHSY-5Y, MRC5) were infected with different MuV strains. The total RNA was extracted, reverse transcribed and the relative expression of mRNA for IFN-activation associated genes was measured by qPCR. Irrespective of the cell lines used in our experiments, we show a similar trend of expression levels for analysed genes. Generally lower levels of mRNA expression were obtained upon stimulation of infected cells with poly(I:C) compared to poly(I:C)-stimulated uninfected cells, especially for wild-type MuV strains. Significant difference in gene induction was observed between the group of vaccine and wild-type MuV strains, latter inducing genes to a far lesser extent. We further investigated defective interfering particles in vaccine and wild-type MuV strain and their contribution to the induction of cellular response. Our preliminary results indicate that influence of these particles depends on a cell type chosen for infection. The results of our study demonstrate that MuV vaccine strains are stronger inducers of IFN-activation associated genes than wild-type MuV strains.


Energy and resource saving method of convective dehydration for the production of stockfish has been proposed. According to this method the dehydration process consists of a continuous initial phase and some further combined periods. These combined periods of dehydration consist of phases of drying and relaxation of moisture in fish. The technical result of this method includes effective fish dehydration, reduced wastes of electrical energy, rational usage of the heat carrier, resources saving work of the drying equipment, and improving quality of production.


Computer modelling of cryocoolers has emerged as a major research area in the last 45 years. In this paper, the authors describe a computer model for two-stage Gifford McMahon cycle cryocooler. The model is developed based on certain simplifying assumptions. It starts with the computation of ideal refrigeration effect that can be obtained from the cryocooler. The model then computes different losses in the system giving the net refrigeration effect available from the cryocooler. Measurements are performed to get the input data for the model from the machine. The input data are pressure-volume variations, temperature and refrigeration effect at both expansion stages. The model predictions have been found to be very close to the actual results obtained from the machine. The model is used further to study the effect of different parameters like phase angle between pressure and volume variations, frequency and also of the regenerator materials on the refrigeration available at first and second stage of expansion.


ABSTRACT Identity crisis has become a major source of inefficiency and ineffectiveness of individuals and organizations. One of the strategic ways for solving this crisis is through identifying the culture (personality) of organizations. The study identified organizational culture typologies of construction firms in Ghana, which is in response to the need for culture studies in construction and the unavailability of such studies in the Ghanaian Construction Industry. The study was quantitative; data were collected from Indigenous contractors in Ghana using a questionnaire survey. Analysis was done using Mean Score Ranking, Relative Importance Index and Exploratory Factor Analysis. Workplace Culture, Business Culture, System Culture and Group Culture were the identified typologies for the study. The cultures identified reveal the strategic areas of construction organizations which need management planning and commitment, to help in reshaping them to be competitive in the business environment.


F orty five rats were divided into 3 groups {carbon tetrachloride (CCl4), iron, and iron + CCl4}. The rats received subcutaneous injection of Ccl4 twice weekly with or without intraperitoneal injection of iron dextran once weekly for 8 weeks in addition to absolute ethyl alcohol 5% in the drinking water. In case of iron alone, the liver showed few areas of lytic necrosis, infiltration of mononuclear cells and deposition hemosiderine particles throughout the whole liver, especially in portal tract, midzonal with periportal hydrobic degeneration. However, upon administration of iron with CCl4, lesions were congestion, hemorrhage, hydropic degeneration, necrosis and pseudolobulation, in addition to severe infiltration of inflammatory cells and hemosiderin particles within the portal tracts. In conclusion, iron found to increase the severity of hepatotoxicity induced by CCl4. Key words: (Iron overload, CCL4, Hepatic toxicosis, Rats).


• the interaction between collective bargaining as a process (at workplace; sectoral and subsectoral level) and the process of worker participation through workplace forums and similar structures; and • the demarcation of topics for collective bargaining from topics dealt with by workplace participatory structures. This article is concerned with the first aspect the organizational and institutional sides of the process.


The conformational propensity of the 20 naturally occurring amino acids was determined in aqueous 3-[N-morpholino]propane-sulfonic acid (MOPS) buffer, protein interiorlike [nonmicellar sodium dodecylsulfate (SDS)] and membrane-like environments (micellar SDS and lysophosphatidylglycerol/ lysophosphatidylcholine micelles) using a single ''guest'' position in a polyalanine-based model host peptide (Ac-KYA13K-NH2). This model system allows the intrinsic a-helical or b-sheet propensity of the amino acids to be determined without intraand interchain side chain interactions. The overall environment dependence observed for the conformational propensity for the amino acids studied confirms the importance of determining propensity in lipidic environments to better elucidate the biological functions of proteins. The hydrophobic interactions between peptide side chains and lipids appeared to be the primary forces driving the conformational induction in lipidic environments of the model peptides studied. Finally, when comparing the results of these studies with those reported in the literature, the local environment was found to highly influence 65% of the 20 naturally occurring amino acids. q 1997 John Wiley & Sons, Inc. Biopoly 42: 489–498, 1997


Category: Ankle, Ankle Arthritis Introduction/Purpose: Ankle arthrodesis (AA) and total ankle arthroplasty (TAA) are often associated with significant postoperative pain; this may be mitigated by the use of peripheral nerve blocks (PNB). While smaller studies suggest PNB to be an effective pain management option in foot and ankle procedures, large scale comparative effectiveness data in ankle arthrodesis and TAA is lacking. Therefore, the purpose of this national study was to evaluate PNB utilization patterns and its impact on outcomes such as opioid utilization. Methods: This retrospective cohort study utilized data from the nationwide Premier Perspective claims database (2006-2016) on AA (n=10,049) and TAA (n=4,977) procedures. Mixed-effects models estimated associations between PNB use (defined from inpatient billing) and opioid utilization (during the total hospitalization period and specified by each day), hospitalization costs, length of stay (LOS), admission to skilled nurse facility (SNF), opioid-related complications, and 90-day readmission. We report odds ratios (OR, or % change for continuous outcomes) and 95% confidence intervals (CI). Results: Overall, PNB was utilized in 8.6% of TAA and 8.5% of AA. Both procedures demonstrate increased utilization of PNB from 2006 to 2016 (2.7% to 11.7% and 5.5% to 11.7% for TAA and AA, respectively). In general, PNBs were utilized less in non- teaching and smaller hospitals and among surgeries performed by a podiatrist (compared to orthopaedic surgeon). After adjustment for relevant covariates, PNB use was significantly associated with decreased opioid utilization during the total hospitalization period for both TAA (-15.7%, CI 22.8; 7.9%) and AA (-16.0%, CI 21.9%; 9.7%); this was particularly driven by a decrease in opioid utilization on the day of surgery. PNB use was not associated with reductions in LOS, cost of hospitalization, discharge to SNF, complications, 90-day readmission. Conclusion: In this first national study on PNB use in ankle procedures we found an overall low use of PNB while an increasing trend in utilization was observed. Importantly, PNB use was associated with significant opioid-sparing effects (especially on the day of surgery), while no effects were seen for other outcomes. Given the current low utilization rate, increased use of this analgesic technique may translate into more benefits in terms of clinical outcomes and resource utilization.


Weed is a plant that grow in undesirable places, especially in the location of cultivated plants. Alelochemical use as bioherbicide is one of the ways in weed control and is safe for the environment. The study was conducted to test the potential of P. jiringa fruit peel extract as bioherbicide on the germination and growth ofA .spinosus and P.conjugatum weeds. The study used a completely randomized design (RAL) with the concentration of extract (P) used consisting of 6 treatments, namely P1 = 0 (control), P2 = 0.1; P3 = 0.2; P4 = 0.3; P5 = 0.4; and P6 = 0.5 g / ml. each treatment was repeated 5 times. The results of the study showed that the concentration extract of 0.5 g / ml was an inverse concentration to inhibit the weed seeds germination ofA.spinosus and P. conjugatum. Good concentration extract to inhibit growth A. spinosus and P. conjugatum is 0.3 g / ml which results in inhibition of plant height, root length, wet weight and dry weight. Based on research conducted on fruit peel extract P. jiringa has the potential as a bioherbicide.


Sodium super ionic conductor (NASICON)‐type Li1.3Al0.3Ti1.7(PO4)3 (LATP) is one of the most promising solid‐state electrolytes (SSEs) owing to its high Li‐ion conductivity, high stability with air, and low cost. However, LATP is less widely deployed due to its high incompatibility with lithium metal. Herein, a facile and inexpensive spray‐coating approach is proposed to construct a thin 3D organic/inorganic composite layer of a commercial boron nitride‐based release agent (BNRA) onto LATP. Apart from protecting LATP, this interfacial BNRA layer enables Li‐ion migration through BN defects and affords low resistance at BNRA/Li interface due to in situ formation of Li–N. Compared to bare LATP, which fails to support Li stripping–plating process in a lean‐lithium Li/Li symmetric cell (2 µm), BNRA‐LATP runs for ≈1800 h. The assembled lean‐lithium LiFePO4 (LFP)/BNRA‐LATP/Li solid state batteries (SSBs) deliver a specific capacity of 150.9 mA h g–1 at 0.5 C with minor capacity decay after 500 cycles. Besides, the BNRA layer eliminates thermal runaway risks of LATP‐based SSBs by fast in‐plane thermal dispersion. This work demonstrates a facile LATP‐protection strategy regarding Li incompatibility and thermal runway issues, and pinpoints the interfacial formation mechanism, fulfilling the pursuit of high‐performance low‐cost SSEs.


INTRODUCTION: During the last decades, the abuse of various drugs has increased considerably. This situation resulted in the development of different procedures for the detection and determination of the target drugs in various matrices, such as urine, serum, saliva, hair etc. In many cases a two -stage process is generally employed for drugs of abuse testing in urine or other body fluids. At first, an appropriate screening test is used to differentiate between negative and positive samples. Various types of immunoassays can be used as screening tests. Alternatively, simple chromatographic procedures such as thin-layer chromatography (TLC) can be used for the same purpose. Results of positive screening tests are confirmed by a second technique such as gas or high-performance liquid chromatography with mass spectrometry detection (GC-MS, HPLC-MS). The sensitivity of the instrumental techniques used for the confirmation and detailed analysis may not be sufficient to handle the samples directly, without preconcentration of the target compound(s). That's why the targets present in urine or other body fluids are usually extracted before chromatography is applied. There are two basic types of extraction )


Officials from NASA and the private space company Blue Origin have signed an agreement that grants the company use of a historic test stand as the agency focuses on returning to the Moon and on to Mars, and America's commercial space industry continues to grow.


The primary mode of treatment for desmoid tumors is surgical excision. However, high recurrence rates (39-79%) have been reported when surgery is used alone. The role of adjuvant radiotherapy after surgical resection of primary disease is controversial and should be based on a balanced discussion of potential morbidity from radiotherapy and local recurrence. In this patient, the maximum dimension of tumor was 21 cm. This is a larger chest wall fibromatosis than has been reported thus far, to the best of our knowledge. In this case, post-operative margins were free, but in view of the large initial tumor size and potential morbidity in case of any future locoregional recurrence, post-operative adjuvant external beam radiation was delivered. An image guided intensity modulated radiotherapy technique was chosen to spare adjacent breast and lung parenchyma, and tolerance of these structures was well respected. This case provides insight into this treatment approach.


Severe viscous fingering during water flooding of heavy oil leaves a large amount of oil untouched in the reservoir. Improving sweep efficiency is vital for enhancing heavy oil recovery. This study presented a laboratory study for improving sweep efficiency by alkaline flooding in heavy oil Reservoirs. This included glass-etched micromodel flooding tests, one-dimensional flooding experiments and three-dimensional physical model study. The micromodel tests show that W/O droplet flow plays a prominent role in the alkaline flooding to improve sweep efficiency. There is a minimum alkaline concentration that generates the W/O droplet flow, and the W/O droplet flow is more obvious with the alkaline concentration increasing. A series of flood tests were conducted using 325 mPa · s, 2000 mPa · s, and 3950 mPa · s heavy oils to assess the effectiveness of W/O droplet flow in alkaline flooding for enhanced heavy oil recovery. The flood tests results demonstrate the considerable potential for improved heavy oil recovery by alkaline flooding, and moreover, the incremental oil recovery has been found to increase as the alkaline concentration increases. The result obtained in three-dimensional physical model study indicates that the sweep area can be greatly improved by the formation of W/O droplet flow in alkaline flooding.


The article proposes an overview of the dialectics between the mimetic and the constructive in Theodor Adorno's Aesthetic Theory. This elaboration will be used to present the article "Transparencies on Film", in which the author discusses the specificities of this medium and the possibilities of resistance that it presents as a work of art in the Cultural Industry. One of the central aspects in this debate is the claim of immediacy and verisimilitude of the photographic, which, at first, would inhibit the constructive possibilities of the work, a fundamental issue for the conceptual architecture of the Adornian Aesthetic.


Abstract Children are beginning to learn about computers at school, but more fundamental changes in their education will occur as computers are used across the whole curriculum. Although some psychologists are playing pioneering roles, the discipline of psychology seems largely unaware of the deep changes just starting in education. Yet psychology has the methodology and subject matter knowledge to make a central contribution. In addition, computers in regular educational use have great promise as research facilities, possibly allowing at last good control to be combined with realism in educational research, and giving new hope for a theory of human learning. Psychologists must be more active in the development of educational computing, and in the public policy debate that will determine the future of our children's education.


Purpose: Although intraductal papillary mucinous tumor (IPMT) and mucionus cystic tumor (MCT) share many common features, they are 2 clinically different disease entities. The aims of this study were to compare the clinicopathological characteristics of IPMT and MCT and to find molecular markers for making the differential diagnosis between IPMT and MCT Methods: Forty-one patients with IPMT and 29 MCT patients who all underwent resection between 1994 and 2003 were enrolled in this study. After one gastrointestinal pathologist reviewed the pathological slides, we compared the clinico-pathological features of the two diseases. Immunohistochemical staining with using 17 biological markers was performed to find useful molecular markers for making the differential diagnosis. Results: Besides the clinical features like gender, the tumor size and location, the patient's age and the radiological images, we found differences of the expressions of PR(p Conclusion: PR, ER, MUC2 and MUC5A can be useful in making the final differential diagnosis between IPMT and MCT. Considering the different gene expressions, further studies are needed to clarify the different pathogenesis of these two diseases entities.


Abstract : Complex interactions among military, technical, geopolitical, and socioeconomic factors constitute major problems for counterinfiltration programs intended to inhibit the movement of hostile forces across defined boundaries. This report describes two versions of an on-line computer program that incorporates the methodology of a model of border control developed in RM-6250; it enables the user to analyze insurgency situations without mathematical manipulations. The computerized versions of the model permit the ready investigation of specific situations and the rapid testing of new concepts with regard to their probable utility under different contingencies. It also permits testing of quantitative sensitivity analyses of candidate border security systems and programs. Outputs include a detailed account and projected time sequence of the number of guerrillas in the area of interest as a result of infiltration, interdiction, recruitment, and attrition. For any future date, these numerical data are given in terms of actual numbers, area densities, and rates of change.


In the traditional numerical simulation of unsteady channel flow,the characteristic method and the Preissmann method are usually used.It is excellent in keeping the balance of the quantity of water by using the characteristic method;but the computational efficiency need improved in nowadays.Though the Preissmann method has high efficiency,it can't keep the balance of the quantity of water.With the strong points of the methods reviewed ahead,a 1D numerical model of unsteady flow based on finite volume method is built.And the floods of Huaihe River and Shiguan River are used to check the accuracy of the model.The result shows that this model is really good in simulating the characters of unsteady flow and keeping the balance of the quantity of water.


Atomic structure and surface stress changes are measured simultaneously by surface x-ray diffraction and by the crystal curvature technique during the deposition of Ni on W~110!. Substantial lateral shifts of up to 0.5 A of the W atoms upon deposition of the first layer Ni are detected. This unexpected restructuring of the W surface is correlated with compressive surface stress of t 11 ¯ 0521 N/m and t 001522.1 N/m. The atomic coordinates for Ni and W atoms of this c-(137) structure are given and they indicate the formation of chains between Ni and W atoms along W@11 ¯ 1#.


In this brief correspondence it is argued that Rappaport's formulas which were developed to calculate the inverse of blocking probability for Erlang loss and Erlang delay systems should be revised. These formulas can readily be solved by taking advantage of the monotonic property of overflow traffic as suggested earlier in the literature.


The scattering of rotationally cold N2 from Ag(111) results in angular momentum alignment and orientation of the scattered molecules; measurement of the angular momentum polarization as a function of exit angle, final J state, and exit translation energy provides direct information on the dynamics of the collisions. In this paper, the orientation of the angular momentum vector of the scattered N2 molecules, A{1}1−(J) has been measured for slow, medium, and fast groups of molecules in single rotational states at fixed exit angles. With normal incidence scattering (θi=0°) and off‐normal detection, for a given final J state, the ''slow'' molecules have a higher probability of tumbling backwards (''back spin'') than the ''fast'' molecules. Conversely, for glancing incidence scattering (θi=30°) with quasi‐specular detection, the opposite trend is observed: the slow molecules have a higher probability of tumbling forwards (''top spin'') than the fast molecules. These experiments were simulated and analyzed usin...


Based on systematical investigation of present digital observation situation of well-water level,we have analyzed the yearly,monthly and daily dynamic behavior characteristics at different levels,and evaluated the monitoring efficiency of earthquake precursor on the basis of the earthquake cases.The result shows:(1) 90% of the wells,its′ daily and monthly behaviors have some regularity,can exert its′ efficiency in the medium-term precursory monitoring,(2) 50% of wells,its′ daily and monthly behaviors have some regularity and have no step-change and impulse over trinal mean squared error,can exert its' efficiency during the short-term and short-impending-term precursory monitoring.The result also shows that there is impulse-type anomalies,affected exertion of earthquake monitoring efficiency severely,which accounts for about half of water level wells.


Mycobacterium bovis is a member of the M. tuberculosis complex, a group composed by species with high genetic homology. The pathogen is the etiological agent of bovine tuberculosis, an important zoonosis that is mainly transmitted by inhalation of infectious droplet nuclei or by ingestion of milk and crude milk derivative products from tuberculosis cows. The definitive identification of M. bovis, up to species level, is time consuming and difficult. In this work, the objective was to standardize a polymerase chain reaction followed by an enzyme restriction analysis in order to identify the M. tuberculosis complex in milk, without a microbiological isolation step. Reference strains and raw milk seeded with M. Bovis, were used as the starting material.  A 441pb fragment of the hsp65 gene was amplified and digested by two restriction enzymes BstEII and HaeIII. The obtained profile was used to identify the M. tuberculosis complex in milk. The minimum limit of detection of M. bovis in milk was 10CFU/mL. PRA methodology proved to be a specific and sensible method. It can be used to assist the microbiological and biochemical methods commonly used to identifying the bacilli in clinical samples, as milk  Key word: Detection limit (PRA), Mycobacterium tuberculosis complex, milk Mycobacterium bovis, Restriction Enzyme Analysis (PCR),


Caregivers of children with cancer are at risk for distress, anxiety, and posttraumatic stress symptoms. In particular, fathers of children with cancer present with unique coping challenges related to traditional gender roles and societal expectations. Identifying effective interventions to help these caregivers is critical. Creative therapies, such as music therapy, may be particularly beneficial. Prior research suggests that music therapies such as rhythmic drumming help individuals to relax and decrease anxiety and stress. The present article reviews literature on music therapy, rhythmic drumming in particular, as a potential therapeutic option for fathers of children with cancer. Further, the authors also propose a study designed to assess the feasibility and efficacy of music therapy in caregivers of children with cancer. Improved medical treatments and supportive care have resulted in increased survival rates of children and adolescents diagnosed with pediatric cancers, with overall 5-year survival rates approaching 85% [1]. However, almost sixteen thousand youth are diagnosed each year [2], significantly altering life for these children and their caregivers [3]. In addition to providing physical and emotional support to their child [4], caregivers must tend to their own psychosocial needs. In about 80% of families, one or more caregivers experience posttraumatic stress symptoms while their child is receiving treatment for cancer [5]. There is growing evidence that creative therapies, such as music therapy, have a positive impact on the psychosocial well-being of both pediatric and adult patients being treated in medical settings [6-9]. Despite these findings, there is limited research examining the effect of music therapy on caregivers. Music therapies typically involve the interaction between a trained musician, who uses music to help facilitate selfexpression and relaxation, and patients, who can either listen to the live music, or better yet, take an active role in making the music themselves [10,11]. Because it is easily adaptable in length and structure, music therapy is well suited for medical settings where psychosocial intervention may be needed for as short as 15 minutes of relaxation prior to a procedure to as long as a 60-90 minute groupor individual-session to facilitate meaningmaking and self-expression [12,13]. Also, there is no need for patients to have any prior experience with music, making it easier to facilitate patient involvement. Patients who may not have interest in or comfort with traditional therapy may find music therapy an acceptable alternative. Music therapy is particularly well-suited for use among child and adolescent patients with cancer, who experience much uncertainty throughout the cancer journey [14-16] and sometimes struggle to express and resolve emotions related to this uncertainty [17]. Research suggests that music therapy helps individuals with cancer cope with loss, grief, and physical and emotional suffering, as well as make meaning and restore or reestablish identity [13]. In particular, music therapy has become popular for use with children with cancer. Children with cancer report finding support and comfort in challenging issues after participating in brief music therapy sessions [18,19], and their parents report improvements in family communication, as well as their child's self-expression and internalizing and externalizing problems. [12,20]. What is less well known, however, is the impact of music therapy on caregivers of children with cancer. Over the past few decades, there has been an increased focus on exploring creative stress management strategies and interventions for family caregivers [21,22]. Among caregivers of adult patients, preliminary research suggests that music therapy promotes improved well-being. For instance, one study found positive effects on reducing anxiety, depression, and blood pressure among caregivers of adult patients with cancer following either a nurse-led or recorded music intervention that involved 30 minutes of listening to live or prerecorded relaxing music [23]. There has also been evidence supporting the use of music therapies for caregivers of adults with Alzheimer's or dementia, as well as for bereaved or palliative care caregivers [24,25]. Specifically, the quality of interactions and visits between caregivers and their patients with late-stage dementia was Central Cutillo et al. (2015) Email: Ann Pediatr Child Health 3(5): 1069 (2015) 2/3 improved with participation in a music intervention involving singing, dancing, and rhythm playing [26]. Qualitative research also suggests that music therapy in home-based hospice care settings facilitates self-expression and meaning-making among caregivers who have lost a loved one to advanced cancer, thereby promoting a sense of support for these caregivers [24]. Caregivers of children with cancer represent a unique group because they experience informational, practical, emotional, social, and existential stressors all at once [27]. There is data to indicate that parents of children with cancer are at risk for distress [28], anxiety, and posttraumatic stress [29,30], highlighting the need for effective psychosocial interventions. Fathers of childhood cancer patients are a particularly understudied group, as most research involving parents has targeted mainly mothers. Qualitative research with fathers suggest that they struggle to overcome the stress and emotional burden of having a child with cancer while also feeling pressured to maintain traditional gender roles and be a "rock" for the rest of the family [27,31]. Music therapy may be of special interest to fathers because of the potential to feel more comfortable expressing themselves in a group of other men when there is an activity to engage in and no pressure to engage in one particular style of coping. Music therapy may be particularly beneficial for caregivers of children with cancer because it is easily facilitated in a hospitalsetting, can be done individually or in a group setting, and can be utilized during all phases of treatment (diagnosis, treatment, bone marrow transplant, palliative care or treatment completion) [18]. One protocol in particular, HealthRHYTHMS, has shown promise as an empirically supported [32-36] drumming intervention that was developed by a neurologist, Dr. Barry Bittman, in collaboration with a well-known drumming company, Remo Inc. This protocol involves group therapy sessions in a drumming circle format, has been utilized in various medical specialties, including oncology, cardiology, and pulmonary, and appears to have a positive effect on both physical and psychosocial outcomes. For instance, among healthy adults, an improvement in stress-related hormones (e.g. cortisol) and natural killer cells was evidenced after just one session of group drumming [32,35]. Improved mood, decreased burnout, and group cohesiveness have also been reported by nursing students, corporate employees, and long-term care workers in a residential facility following participation in this drumming protocol [33,34,36]. Despite these promising findings, the efficacy of this protocol has not been examined among caregivers of children with cancer or fathers in particular. Thus, the present investigation will involve implementing a rhythmic drumming intervention based on the HealthRHYTHMS protocol for fathers of children with cancer. Specifically, groups of fathers of children undergoing treatment or having undergone treatment for cancer will be recruited to participate in a 6-week drumming intervention. Fathers will be invited to attend as many sessions as they are able, depending on their level of comfort and engagement. In addition to collecting demographic and illness-related information, caregiver distress and burden will be assessed. Caregiver distress will be measured using psychological measures of distress such as the Brief Symptom Inventory 18 (BSI-18) [37] or the National Comprehensive Cancer Network's Distress Thermometer (NCCN-DT) [38]. Caregiver burden will be assessed using the Care giving Burden Inventory [39]. An informal assessment using a Likert scale of each father's participation will be completed during each session by the trained facilitator with focus on the participant's level of engagement and self-disclosure. Similar assessments have been created by researchers and utilized in other studies of drumming interventions [12,40]. Once participants engage in the drumming protocol, we hypothesize that fathers will report less distress and psychosocial burden brought on by having a child treated for cancer. In order to measure the efficacy of the intervention, the researchers could administer similar assessments to a group of fathers from the same population participating in a therapy group without the drumming component. Results could be compared to assess whether the intervention provides a unique relief from distress. In addition to contributing to the limited research examining fathers of pediatric cancer patients, this research will provide much needed data on the feasibility and efficacy of music therapy for caregivers in a pediatric hospital setting.


Orphanhood is a tragic consequence of the HIV epidemic worldwide and often compounds pre-existing malnutrition and ill-health among HIV-infected children. As the number of HIV orphans overwhelms the capacity of extended biological families to care for these children, a viable option is to provide institutionalized residential care for these children. This study aims to understand the health status of HIV orphans in a well-structured model institutional facility in India using prospective longitudinal analysis of growth and nutritional status of these children. Eighty-five HIV-infected orphan children residing at Sneha Care Home, Bangalore,for at least one year, (between June 2008-May 2011) were included for analysis. Prevalence of anemia at entry into the home was 40%, with the cumulative incidence of anemia during the study period being 85%. At baseline, 79% were underweight and 72% were stunted. All children showed significant increase in weight (mean weight-for-age Z score change: -2.93 to -1.75, p<0.001) and height (mean height-for-age Z score change: -2.55 to -1.62, p<0.001) irrespective of ART status. These findings suggest that good nutrition even in the absence of ART can bring about improvement in growth. The Sneha Care Home model indicates that a holistic approach to combating HIV in severely malnourished orphan children is effective in improving nutritional status and may contribute towards optimal management of HIV orphans globally.


Kiosks are widely used in order to provide "localized real-time information," "interactive touch-control services," and "value-added integrated marketing service". We review recently introduced kiosk related research results. Then, we propose our design of a kiosk system for local area tourism. The screen of the system consists of a video view, two image views and an online shopping mall.


It is introduced how to shape standard bevel wheel of 3D with application programme interface(API) and internal standard function in Solid Edge. The inputting of bevel wheel′s parameters on a style of standard control with interface of Visual Basic is realized and the standard bevel wheel of 3D with parameters input is formed.


Huang Bin, Ph.D. in Philosophy, Deputy Director of the Center for Public Purpose Financing Research, Nanjing University of Finance and Economics, Jiangsu, China. Email: email@example.com Address: 128 Railway N St, Gulou, Nanjing, Jiangsu, China, 210003.Xu Caiqun, Masters degree, Finance and Taxation Institute, Nanjing University of Finance and Economics, Jiangsu, China. Email: email@example.com Address: 128 Railway N St, Gulou, Nanjing, Jiangsu, China, 210003.The paper investigates empirically the intention of Chinese rural students for the Secondary Vocational Education (SVE) and its determinants by using the survey data of Zhejiang, Anhui and Shanxi provinces collected in 2010.Results show that Chinese rural students nowadays have a strong tendency to accept the Secondary General Education (SGE), but their intention for SVE is relatively low.A list of variables is found to influence junior students intention in analysis of multinominal logistical regression. Students choice between SGE and SVE is mostly affected by personal academic performance, while family economic status exerts a significant effect on the choice between Employment and SVE. Whether junior students know about the governments financial aid for rural SVE students or not wont alter their intention. According to the survey results, it is strongly recommended to abolish the policy that aims to maintain the roughly equal enrollment between SGE and SVE. In addition, the central government should consider increasing the amount of financial aid for rural SVE students, especially for those in Central and Western China. The authors suggest that these measures will help students from low income families choose SVE and get professional education instead of entering the labor market too early. DOI: 10.17323/1814-9545-2012-2-140-158


Citation: Wang L, Tay ACY, Li J and Zhao Q (2022) Editorial: Computational Predictions, Dynamic Tracking, and Evolutionary Analysis of Antibiotic Resistance Through the Mining of Microbial Genomes and Metagenomic Data. Front. Microbiol. 13:880967. doi: 10.3389/fmicb.2022.880967 Editorial: Computational Predictions, Dynamic Tracking, and Evolutionary Analysis of Antibiotic Resistance Through the Mining of Microbial Genomes and Metagenomic Data


A multicausal model of adolescent homelessness is proposed, based upon the notion that homeless youth suffer from emotional, social, and cultural deprivation. The model was tested in a sample of homeless adolescents (n = 54) and a similar, but not homeless, control group (n = 58). Emotional deprivation was assessed on the Parental Bonding Inventory (Parker, Tupling,&Brown, 1979), whereas social and cultural deprivation were assessed on the Family Environment Scale (Moos&Moos, 1981). The homeless adolescents were found to be significantly more deprived emotionally, socially, and culturally than the controls. The results indicate support for a deprivation model of adolescent homelessness with implications for public policy and intervention planning.


In future space developments, welding in space may be required for repairs to the International Space Station and for constructing lunar bases and space structures. This paper describes the results of applying the space diode laser (DL) welding process, which the authors proposed in 2002. To use the DL welding process in space, it is necessary to prevent metal deposition on optical devices. We investigated a technique for preventing metal deposition in which the nozzle is installed at optical devices and a shielding gas is ejected from the nozzle outlet. Metal deposition can be reduced by blowing inert gas from the nozzle. The shielding gas argon completely prevents metal deposition on optical devices when the argon pressure in the nozzle is over 19.9 Pa and argon is ejected from the nozzle outlet.


© 2012 Aladele et al., licensee InTech. This is an open access chapter distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Science of Plant Tissue Culture as a Catalyst for Agricultural and Industrial Development in an Emerging Economy


FIELD: medicine. SUBSTANCE: set intends for helping to proper sequent oral take of pharmaceutical nutrients. Set has single dosage of pharmaceutical active substance which should be given permanently with specific repetition, single dosage of nutrient which should be given after dosage of active substance is taken; card-blister which has single dosages for removal. Single dosages of pharmaceutical active substance and of nutrient tare disposed in card-blister in order of application. Set helps patients to understand better the way of taking medicines and mode of take when active ingredient is taken with permanent repetition being different from daily dosage and when nutrient is taken in days between days of take of active ingredient. EFFECT: high efficiency. 14 cl, 5 dwg, 9 ex


This study intends to determine whether there is a significant relationship between the reading performance and field dependence/independence cognitive styles of Iranian learners of English as a foreign language. In order to perform this research, 60 intermediate level EFL learners, both male and female, were selected through a placement test and subsequently their cognitive styles were determined using the Group Embedded Figures Test (GEFT). Furthermore, their performance on a reading comprehension test was assessed. To test the claim that there is a significant relationship between field dependence/field independence styles and their performance on the reading test, a correlation was run between the two sets of scores. The results indicated that field independent participants have an advantage over field dependent ones, and females outperformed their male counterparts on both the GEFT test and the reading comprehension test.


This paper briefly introduces the water-proof system of the high-speed railway bridge surface at home and abroad,and expresses the importance of premier treatment agent in water-proof system and the existing treatment conditions.The performances,characteristics and application condition of the high infiltration modified epoxy material and its advantages while used as the premier treatment agent of passenger line bridge surface are introduced.


Chronic Myeloid Leukaemia (CML) is a triphasic disease which typically presents in chronic phase with risk of progression to more aggressive phases in a certain proportion of patients. Accelerated Phase (AP), as described in the pre-Tyrosine Kinase Inhibitor (TKI) era by Kantarjian et al in 1988, is an intermediate stage with a poor median overall survival (OS) of ≤18 months without haematopoietic stem cell transplantation (HSCT). Since TKI therapy has revolutionized CML treatment, a significantly improved OS has been seen in most CML patients, including those in AP. Not all CML-AP patients require HSCT upfront nowadays and many are able to achieve major molecular remission (MMR) and favourable OS on TKI therapy. However, updated classifications of CML-AP by the World Health Organization (WHO) and European LeukemiaNet (ELN) do not reflect these significant advances in the TKI era. There is a need to re-evaluate the CML-AP classification that will have an impact on treatment decisions for CML-AP patients. In this study, we explored the association between various haematological parameters at diagnosis and the probabilities of OS and progression-free survival (PFS) of CML-AP patients on TKI therapy. Overall Survival (OS) and Progression-Free Survival (PFS) trends of 75 newly diagnosed CML-AP patients treated with frontline TKIs between 2000 to 2013 from Singapore General Hospital and Seoul St. Mary9s Hospital in South Korea were retrospectively analysed with regards to demographic and haematological parameters, such as cell counts from serum and bone marrow at diagnosis, using cox proportional hazards analysis. Survival was also compared using log-rank test with Bonferroni corrections between CML-AP patients and 227 CML Chronic Phase (CML-CP) high-risk Sokal and 34 Blast Crisis (CML-BC) patients on TKI-based therapy. OS was defined as duration from diagnosis of CML-AP to death from any reason. PFS was defined as duration from disease diagnosis to the first occurrence of progression or death due to CML. As a whole, CML-AP patients treated with frontline TKI had survival that paralleled CML-CP high-risk Sokal patients (p-value = 0.694 for OS, p-value = 0.258 for PFS). Most of the death and progression occurred less than 3 years of starting TKI therapy (69.2% for OS, 84.6% for PFS). Multivariable analysis in CML-AP patients showed that male gender, bone marrow (BM) blasts ≥10% and clonal chromosomal abnormalities (CCAs) at diagnosis were associated with poor OS (Hazard Ratio (HR) 18.53, p-value = 0.013; HR 1.16, p-value = 0.010; HR 5.05, p-value = 0.044, respectively) and poor PFS (HR 12.96, p-value = 0.021; HR 1.17, p-value = 0.007; HR 8.84.05, p-value = 0.008, respectively). CML-AP patients with all 3 of these risk factors experienced the worst OS compared to those with 1 or zero risk factors (p-value Our findings suggested that CML-AP was a heterogeneous group with varying survival probabilities on TKI therapy. Male gender, BM blasts ≥10% and CCAs at diagnosis were risk factors shown to be predictive of survival probabilities, and identified a high-risk sub-group among CML-AP patients with inferior OS and PFS rates similar to CML-BC patients. Aggressive chemotherapeutic strategies including HSCT should be warranted in these patients. However, TKI therapy alone with close molecular surveillance may be a reasonable option for optimally responding low-risk CML-AP patients who are not eligible for HSCT. Disclosures Kim:BMS: Consultancy, Honoraria, Membership on an entity9s Board of Directors or advisory committees, Research Funding, Speakers Bureau; Novartis: Consultancy, Honoraria, Research Funding, Speakers Bureau; ILYANG: Consultancy, Honoraria, Research Funding; Pfizer: Honoraria, Membership on an entity9s Board of Directors or advisory committees, Research Funding, Speakers Bureau. Goh:BMS: Honoraria; Novartis: Honoraria, Membership on an entity9s Board of Directors or advisory committees, Research Funding; Roche: Honoraria; Janssen: Honoraria, Membership on an entity9s Board of Directors or advisory committees, Research Funding; Celgene: Honoraria; Takeda: Honoraria; Alexion: Honoraria, Membership on an entity9s Board of Directors or advisory committees.


This article analyzes the existing trouble of the coordination of construction to economy, society and environment in the process of the construction of our native urban infrastructure. On this base, it also draws a conclusion to the reasonable proportion between urban infrastructure and economy in order to coordinate them.Furthermore, this article brings forward some propulsive suggestions in the accommodation to the society and the reconciliation to the environment.


- This paper deals with the experimental investigation of lignite (L) and wood (W) feedstock in a pilot-scale downdraft gasifier. The study aims to check the compatibility of CaMg(CO 3 ) 2 [dolomite (D)] catalyst, 5% (W/W), with lignite and wood (L+D, W+D) feedstock as an additive to enhance the performance of a 10 kWe atmospheric pressure downdraft gasifier system. Fuel consumption and gas flow rate were found to be 10.01-11.6 kg h -1 and 26.76-29.57 kg h -1 , respectively, for lignite and wood feedstock (with and without catalyst). In lignite, CO and H 2 concentrations were increased by 6.81 % and 4.9 %, respectively, whereas in wood, their concentrations were increased by 8.88 % and 5.1 % when the catalyst was employed with feedstock. The producer gas LHV and cold gas efficiency were increased by 6.02% and 5.75% in lignite and 6.97% and 6.61 in wood, whereas specific fuel consumption decreased by 5.92% (in L), 5.17 (in W) with dolomite feedstock. Tar and Total Particulate Matter (


[Objective] To investigate the effect of transabdominal ultrasound-guided embryo transfer on the outcome of in vitro fertilization-embryo transfer (IVF-ET). [Methods] The data of 461 patients undergoing IVF-ET (including intracytoplasmic sperm injection) therapy for 521 cycles in our Reproductive Medicine Center were analyzed retrospectively. The patients were divided into two groups: the traditional group (group A) and the ultrasound-guided group (group B), including 187 cycles and 334 cycles, respectively. The clinical pregnancy rate, implantation rate, embryo retention rate, and ectopic pregnancy rate between two groups were compared. [Results] The clinical pregnancy rates of group A and group B were 35.8% (67/187) and 38.3% (128/334), P 0.05; the implantation rates were 17.4% (104/599) and 23.2% (179/773), P 0.01; the embryo retention rates were 3.7% (7/187) and 0.3% (1/334), P 0.01; the ectopic pregnancy rates were 3.0% (2/67) and 1.6%(2/128), P 0.05.[Conclusion]Transabdominal ultrasound-guided ET can increase the implantation rate and decrease the embryo retention rate, may be helpful to improve the clinical pregnancy rate and decrease the ectopic pregnancy rate, so it is an effective technique for embryo transfer.


We introduce the design and implementation of DCFS (Dawning Cluster File System), a cluster file system developed for the Dawning4000 LINUX clusters. DCFS provides the single name space and binary compatibility with local file system for users and applications on Dawning4000. In addition, it improves system manageability for administrators by embedded file system management considerations into DCFS implementation and provides an easy use interface. Important features of DCFS are presented, including a global management domain, a communication abstraction layer, pipelined file I/O, enhanced multitask capability in storage servers, and fault-tolerance strategy.


The electrochemical impedance spectroscopy measurements were performed in different frequency ranges at open circuit potential for an alkyd resin coating containing TiO 2 pigment in 3% NaCI solution. The interpretation ofimpedance spectra permitted the determination of the water permeation, formation of blisters and loss of adhesion as well as the delaminated area.


BACKGROUND
Uterovaginal brachytherapy planning is conventionally based on the use of two orthogonal Xray projections. Currently, there is a large development of 3D brachytherapy planning based on the fusion of CT and MRI, which takes into account the extent of the tumor and the location of organs at risk. In this work, we evaluated the dosimetric data and first clinical results in patients with inoperable cervical cancer using MRI/ CT compatible applicator enabling 3D planning.

PATIENTS AND METHODS
Between June 2012 and March 2013, we performed 52 uterovaginal applications in 13 patients with inoperable cervical cancer using Vienna Ring MR CT applicator. Planning was carried out by the fusion of MRI and CT. Target volumes and organs at risk delineation were carried out on the basis of GEC ESTRO and ABS recommendations as well as doses report-ing.

RESULTS
Overall radiotherapy duration was 37- 52 days with median of 45 days. The median total dose delivered to the HR CTV was 88 Gy (70.7- 97.9) EQD2. The median single dose in brachytherapeutic applications was D90 = 6.45 Gy (3.2- 9.82). The median total doses delivered to the rectum, sigmoid colon and bladder were D2ccrectum = 64.2 Gy (54.3- 74.1), D2ccsigmoid = 68.6 Gy (57- 74.7) a D2ccbladder = 73.9 Gy (58.3- 92.6). In 11 patients (84.6%), complete locoregional remission was achieved, in the remaining two patients (15.4%), partial locoregional remission was achieved. Twelve patients (92.3%) had complete regression of the tumor in the cervix, one patient (7.7%) developed metastatic spread to the liver. Yet we did not observe manifestations of a higher degree of toxicity than the first grade, both GI and GU. Late GI toxicity was manifested in two patients (15.4%) and late GU toxicity was manifested in five patients (38.5%).

CONCLUSION
3D brachytherapy planning of inoperable cervical cancer using the fusion of MRI and CT conclusively raises the possibility of the dose escalation to the tumor and significantly spares the surrounding organs at risk. Subsequently, this way of planning leads to better local control of the disease and to lower radiation morbidity.


Abstract— As the amount of data available and shared in the electronic media increases, the threat for its privacy and security also increases. Every organization publishes its data to many recipients for various reasons .Thus preserving the privacy of data during the process of data mining is the aim of Privacy Preserving Data Mining [PPDM]. Multi-trust level is a scenario in privacy preserving data mining where different versions of privacy preserved data are distributed to the users based on their trust level. This work presents three trigonometric based rotation perturbation algorithms for privacy preservation at multi-trust level. These algorithms are applied on three bench marked datasets to generate multiple sequential dataset versions at various privacy levels. The perturbed datasets are evaluated on utility, distortion rate and the ability to prevent linking attacks. The results show that the perturbed datasets have utility comparable to the original datasets and linking attacks are prevented.


We develop a theoretical model for power law tailing behavior of transport in fractured rock based on the relative dominance of the decay rate of the advective travel time distribution, modeled using a Pareto distribution (with tail decaying as ∼ time−(1+α)), versus matrix diffusion, modeled using a Lévy distribution. The theory predicts that when the advective travel time distribution decays sufficiently slowly (α<1), the late‐time decay rate of the breakthrough curve is −(1+α/2) rather than the classical −3/2. However, if α>1, the −3/2 decay rate is recovered. For weak matrix diffusion or short advective first breakthrough times, we identify an early‐time regime where the breakthrough curve follows the Pareto distribution, before transitioning to the late‐time decay rate. The theoretical predictions are validated against particle tracking simulations in the three‐dimensional discrete fracture network simulator dfnWorks, where matrix diffusion is incorporated using a time domain random walk.


Abstract Black Hill is a boulder‐strewn residual of norite standing 45 m above the Murray Plains about 80 km northeast of Adelaide. Between the boulders, the crystalline rock has weathered to a dark‐brown terra rossa‐rendzina soil with calcite, illite, kaolin, and hematite as the principal secondary minerals. At one site on the smooth lower slopes of the outcrop, the material above the norite consists of partially weathered granular fragments with considerable dolomite and some calcite in nodular form. Below the surface, the rock has been weathered along joints to produce the clay mineral nontronite, and between each corestone and this plastic clay there is a zone of laminated but essentially unaltered rock 10–25 cm thick. Pieces of amorphous silica occur sporadically in some joints and on the surface. The dark‐brown soil appears to be related to the present environment but the nontronite in the joint weathering, the dolomite, and the amorphous silica are all consistent with the norite having been inundat...


When an international tax practitioner is asked to recommend a tax efficient holding company location, the UK (unlike Luxembourg, Malta or the Netherlands) does not usually feature at the top of the list.


Abstract The 1H NMR spectra of the skeletal muscle relaxant, mephenoxalone, 1, 5-[(2-methoxyphenoxy) - methyl]-2-oxazolidinone, have been studied at 200 MHz in CDCl3 solution at 20° in the presence of the achiral lanthanide shift reagent, tris(6,6,7,7,8,8,8-heptafluoro-2,2-dimethyl-3,5-octanedionato) europium (III), 2, and the chiral reagent, tris[3-(heptafluoropropylhydroxymethylene)-(+)-camphorato]europium(III), 3. Both reagents 2 or 3 produced significant lanthanide induced shifts for spectral simplification suggesting major lanthanide binding at the carbonyl. With 3, enantiomeric shift differences were observed for the signals of the NH, OCH3, methine CHO, both protons of the CH2O and one proton of the CH2N, and the aryl proton H-6. Direct determinations of enantiomeric excess of samples of 1 appear feasible by use of 3.


The paper examines the monthly forecasting performance of several models of hotel demand in Denmark by nationality. Statistics are covering a period of more than 30 years, and special attention is devoted to the role of seasonality. Deterministic as well as stochastic seasonality is considered. The data generating process is also examined from a more traditional view by estimating an ECM-model where hotel demand is assumed to depend on economic variables like the foreign and Danish CPI and the exchange rate and variables measuring the climate.


Cities are high emitters of greenhouse gases and are drivers of environmental modification, often leading to degradation and fragmentation of ecosystems at local and regional scales. Linked to these trends is a growing threat experienced by urban areas: the risk from hydro-meteorological and climatological hazards, further accentuated by climate change. Ecosystems and their services, though often overlooked or degraded, can provide multiple hazard regulating functions such as coastal and surface flood regulation, temperature regulation and erosion control. Engineering or grey approaches often do not tackle the root causes of risk and can increase the vulnerability of populations over the long-term. However, evidence of alternative approaches such as the role of healthy, functioning ecosystems in disaster risk reduction are still scarce, contentious, and with limited applicability in the urban context. This chapter explores the role of grey, green, and blue infrastructure and in particular hybrid approaches for disaster risk reduction and climate change adaptation to shed light on available sustainable adaptation opportunities in cities and urban areas. We highlight the dependence of cities on ecosystems as a key component of climate resilience building through case studies and literature review. At the same time, we highlight the limitation and drawbacks in the adoption of merely grey or merely green infrastructures. We suggest that an intermediate 'hybrid' approach, which combines both blue, green and grey approaches, may be the most effective strategy for reducing risk to hazards in the urban context.


The chemical basis for antibody specificity has not, so far, been determined. Three major possibilities exist. (1) The large variety of specificities is generated by differences in amino acid sequence in some portion of the antibody molecule.", 2 Each molecule with a given sequence forms a unique set of disulfide bonds, and folds to a unique conformation under physiological conditions. (2) The specificities are generated predominantly by the arrangement of disulfide bonds.3 Antibody molecules which differ in primary structure certainly exist (genetic variants, for example), but the number of possibilities is much too small to account for the number of possible specificities. However, each primary structure may lead to a large number of distinguishable molecules by formation of different sets of disulfide bonds. Once the location of disulfide bonds is fixed, each molecule folds to a unique conformation under physiological conditions. (3) The specificity is generated predominantly by noncovalent bonds.4 Molecules with a given primary structure and pattern of disulfide bonds may be folded into numerous possible conformations. In the presence of antigen (at the site of biosynthesis) a complementary conformation is energetically favored, and this is maintained under physiological conditions. In trying to distinguish between these possibilities, one is hampered by the fact that even highly specific antibody preparations are always chemically heterogeneous. One method exists which circumvents this difficulty. This method involves deliberate destruction of the specific conformation, followed by attempts to regenerate specific activity. A number of studies using this approach have been reported, the most elegant being the work of Karush.' His procedure was to destroy the specific conformation and biological reactivity of an anti-hapten antibody by the action of 8 M urea. Upon dialysis to remove the urea, the antibody protein returned to a globular form and regained almost all of its original activity. This experiment would seem to eliminate possibility (3), since that mechanism for generating antibody specificity would require the presence of antigen (and, presumably, the antibody-forming cell) to produce the biologically active conformation. Karush also showed that antibody activity can be destroyed by breaking disulfide bonds. He speculated that this might mean that possibility (2) for the chemical


Summary OBJETIVES: The ABO group/irregular red cell antibodies (G/A) protocol is a scheme for reducing the number of unnecessary crossmatch tests in selected patients scheduled for surgery. Reduction would lower expenses and risks related to the overuse of such tests. Studying transfusion rates allows us to predict which patients are candidates for application of the protocol. The present study evaluated the impact of the G/A protocol on transfusion rate. PAT I E N T S A N D ME T H O D S: A re t ro s p e c t ive analy s i s of pre - t ransfusion testing of patients in our hospital


The current article presents the design, implementation, validation, and use of a Computer-Aided Control System Design (CACSD) toolbox for nonlinear and hybrid system uncertainty modeling, simulation, and control using μ synthesis. Remarkable features include generalization of classical system interconnection operations to nonlinear and hybrid systems, automatic computation of equilibrium points for nonlinear systems, and optimization of least conservative uncertainty bounds, with direct applicability for μ synthesis. A unified approach is presented for the step-down (buck), step-up (boost), and single-ended primary-inductor (SEPIC) converters to showcase the use and flexibility of the toolbox. Robust controllers were computed by minimization of the H∞ norm of the augmented performance systems, encompassing a wide range of uncertainty types, and have been designed using the well-known mixed-sensitivity closed loop shaping μ synthesis method.


In this paper we have studied the linear time invariance optimal control problems with quadratic performance index, and approximated control variable, state variable and performance index using Chebyshev scaling function method with unknown coefficients. The linear time invariant problems were parameterized based on control-state parameterization technique such that the objective function and the constraints are casted in terms of state variable and control variable. This method was converting the linear time invariance quadratic optimal control problems into quadratic programming problems and the converted problems were solved using MATLAB. Hence we increase the order of polynomial (M), and then the computational results of the proposed methods gave better results. Keywords: Optimal control, Chebyshev scaling function, operational matrix integration. DOI : 10.7176/MTM/9-7-01 Publication date : July 31 st 2019


Jim Bruni and Helene Silverman are professors at Herbert H. Lehman College of the City University of New York, Bronx, NY 10468. They teach elementary school mathematics and conduct workshops and courses for teachers. coins, spinners, dice, and cards). These activities are highly motivational and certainly lend themselves to the use of manipulative materials. However, all too often such activities tend to become supplementary or enrichment experiences that are quite limited in scope and isolated from the rest of the school mathematics program, and the connection between using manipulative materials and learning basic mathematical concepts is weak. The activities in this article emphasize a four-step approach for using


Bass, Foreword. Browning, Introduction. Part I: On the Analytic Relationship. Psychoanalysis and Transference: Yesterday, Today, and Tomorrow. The Construction of the Transference: The Relativity of the "Here and Now" and the "There and Then." Intersubjectivity and the Analytic Relationship. On the Resolution of the Positive Transference: Suggestion, Identification, and Action. Transference and Psychic Reality: Ideas about the Timeless Past in Psychoanalysis. Further Thoughts on the Contemporary Analytic Relationship. Part II: On Freud's Seduction Theory. Fact and Fantasy in the Seduction Theory: A Historical Review. Interpretations of the Past: Childhood Trauma, Psychical Reality, and Historical Truth. Part III: On Unconscious Fantasy. Unconscious Fantasy: Interpretive Construct and Developmental Phenomenon. A Critical Reexamination of Unconscious Mental Representation. Affective Schemas: Toward a Structural View of Cognition and Affect. Notes on the Psychoanalytic Theory of Consciouness and Reflective Awareness. Signorelli: The Parapraxis Specimen of Psychoanalysis. The Interpretation of Dreams Revisited: Interpretation, Primary Process, and Language.


Targeted on the DSP system with core of TMS320DM6446 in the family of Da Vinci DSP,this paper designed and implemented a power module,adopting two pieces of highly effective synchronized power management chips TPS75003 and TPS62040,in order to meet the requirements of the core voltage,I/O voltage and other auxiliary equipment power for DSP system.Meanwhile,three voltage monitor chips TPS3808 are utilized to monitor the voltages produced by the power management chips,ensuring both the reset circuit and the power-on sequence of the core voltage for DSP and peripheral I/O voltage.


Vaccination remains the most effective means by which influenza virus infection can be controlled. Traditionally vaccine production has focused on egg-based technology. Increasingly cell culture-based vaccine production is being used to improve preparedness. Cell cultured based production methods offer significant advantages over traditional egg-based strategies by allowing (i) rapid scale-up (ii) elimination of allergic egg components and (iii) circumvention of issues relating to egg-adaption. Our aim was to improve influenza vaccines and preparedness through the establishment of mammalian cell (Vero)-based vaccines using plasmid-based recombinant flu constructs expressing exogenous miRNA19 (flu-miR19), a regulator of key host anti-viral pathways that has previously been shown to modulate influenza virus replication. We successfully rescued recombinant influenza viruses expressing miR19 using reverse genetics; validated expression of miR19 and showed increased virus replication in vitro that corresponded with increased HA titres and matrix gene expression. Knockdown of miR19 host target genes was confirmed through qRT-PCR to validate the mechanism of action. This new influenza vaccine platform is scalable and can be merged with existing production technology to offer rapid clinical translation and improve vaccine quality and production times. In summary, silencing of anti-viral host genes using a flu-miR resulted in an increase of influenza vaccine and HA antigen yield. We now plan to further augment antigen yield by propagating these viruses in enhanced Vero cell vaccine substrates.


A former interim chair of the Nursing and Midwifery Council, Judith Ellis, has announced her decision to step down from her role as a council member in June.


Disasters in Brazil have been increasing in the latter years. However, the official communication of disasters in remote places is not being done properly by civil defense. Therefore, practical techniques of response and rehabilitation are insufficient. This makes disasters become silent, i.e. socially invisible. In order to make them visible, this sociological study analyzes a disaster case occurred in the year 2008 in Alto Jurua region, state of Acre, Brazil. Based on qualitative research procedures, the study compares the institutional discourse, from official records, and the narratives of the local riverine communities obtained in field research.


The aim of this project was to demonstrate the possibility of ejecting liquid metals using drop on demand printing technology. The plan was to make transducers for operation in the 100 MHz frequency range and to use these transducers to demonstrate the ability to eject drops of liquid metals such as gallium. Two transducers were made by indium bonding piezoelectric lithium niobate to quartz buffer rods. The lithium niobate plates were thinned by mechanical polishing to a thickness of 37 microns for operation at 100 MHz. Hemispherical lenses were polished in the opposite ends of the buffer rods. The lenses, which focus the sound waves in the liquid metal, had an F-number equals 1. A mechanical housing was made to hold the transducers and to allow precise control over the liquid level above the lens. We started by demonstrating the ability to eject drops of water on demand. The drops of water had a diameter of 15 microns which corresponds to the wavelength of the sound wave in the water. A videotape of this ejection was made. We then used a mixture of Gallium and Indium (used to lower the melting temperature of the Gallium) to demonstrate the ejection of liquid metal drops. This proved to be difficult because of the oxide skin which forms on the surface of the liquid. In some instances, we were able to eject metal drops, however, this was not consistent and reproducible. An experiment was set up at NASA-Lewis to stabilize the process of drop on demand liquid metal ejection. The object was to place the transducer and liquid metal in a vacuum station so that no oxide would form on the surface. We were successful in demonstrating that liquid metals could be ejected on demand and that this technology could be used for making sheet metal in space.


Leaf ageing was initiated in wheat leaves by floating excised leaves on distilled water in dark- ness for up to three days. After a given period of time the leaves were blotted and wilted to a leaf water potential (~leaf) of approximately --12.10~k Pa and then placed in a sealed chamber so that the stress- induced ethylene could be determined. The longer the period of leaf ageing the smaller were the levels of stress-induced ethylene. Treatments which are known to delay leaf senescence, such as floating the leaves on solutions of 6-benzyladenine (BA) or in the light instead of in the dark, were found to partly restore or even enhance the stress-induced ethylene levels. For example leaves allowed to age for 1 day whilst floating on 10- ~ mol 1- 1 BA solution produced up to 200% more ethylene than freshly harvested leaves when both were subjected to water stress treat- ment. When BA solutions were applied as foliar sprays to wheat seedlings, the day before wilting treat- ment, the amount of stress-induced ethylene diffusing from the freshly harvested leaves (i.e. no leaf ageing treatment) was significantly increased. This occurred when water stress was induced in the leaves by either immersing the roots of seedlings in carbowax solution or by wilting excised leaves in a stream of warm air. There was a substantial synergistic effect between BA treatment and water stress in relation to the amount of ethylene diffusing from the leaves. This effect was 7.5-fold in experiments where excised leaves were floated on 10-4moll -1 BA solutions for 1 day prior to wilting and 4.7-fold for intact plants where the BA solution was applied as a foliar spray the day before water stress induction by carbowax. We can postulate from the experiments in this paper that leaf ageing (and/or the depletion of an ethylene Abbreviations: BA=6-benzyladenine; IAA=indole-3-acetic acid; IAAsp=indole-3-acetyl-N-aspartate; GLC =gas-liquid chroma- tography ; 0leaf =leaf water potential substrate, probably a photosynthetic product or a substance derived from it) and the level of endogenous cytokinin are probably important factors which deter- mine the amount of ethylene emanating from leaves during water stress. Moreover, the results suggest that wheat shoots may contain sub-optimal levels of cyto- kinins in regard to their potential ability to produce ethylene under stress.


The study investigated the impact of VBI on student grammar comprehension. The purpose of the study was to examine the effectiveness of VBI in enhancing students' grammar comprehension as well as the students' perspectives on using VBI in the classroom. This study employed a quantitative pre-experimental one-group pre-test and post-test research design. A pre-test, post-test, and questionnaire were used to answer the research questions. It was conducted at one university in Indonesia, with the participation of forty students. The result showed that VBI could enhance students' grammar comprehension as the post-test score of the students was higher than their pre-test score. It indicated that the video-based instruction provided students with quality instruction. Moreover, four students' perspectives after VBI implementation were presented. First, the VBI provided was informative that it assisted them to comprehend the grammar materials. Second, VBI was easy to be accessed at any time and from anywhere. Third, VBI given was interesting material. The final point was that VBI met the video quality expectations. To sum up, this learning media effectively improves the students' grammar comprehension.


Scrutiny of the stability, properties, and applications of 2D metals belonging to s‐, p‐, and d‐block series has acquired intense research interest in the past few years. The present report is solely focused to systematically explore the stability and properties of 2D hexagonal (HX) lanthanides employing density functional theory calculations. To probe the dynamical stability of these materials, the phonon dispersion calculation is performed. The mechanical stability is analyzed on the basis of the 2D bulk modulus and elastic constant values. Further, to unravel the electronic properties of the 2D metals, electronic band structure, electron localization function, and the work function values are estimated. Moreover, en route to explore their magnetic properties, spin polarized density of states calculation is carried out and the ground state magnetic behavior is studied by considering ferromagnetic and antiferromagnetic spin configurations. Result explicitly demonstrates that 11 lanthanide metals are dynamically stable as an atomically thin 2D HX films. All of them are conducting in nature exhibiting ferromagnetic behavior in their ground state. These results offer the fundamentals of stability and properties of 2D HX lanthanides which can lay the foundation for exploring their diverse future applications.


The problem of electromagnetic compatibility is one of importance in the VHF-SHF band LEO system design. One of the approaches to resolve this problem is employment of antenna adaptive control methods. But in the case of a simple omnidirectional antenna these methods are useless, as they are based on multielement antennas. The proposed approach to resolve this problem is based on choosing the geometry of the antenna to form a null level of directivity according to the known supply current distribution. An omnidirectional antenna design for satellite terminal use is discussed. It consists of orthogonal crossed dipoles (each in x, y, z axis) possessing a common center. That system of three dipoles is able to form a null level of directivity according to their size ratio and power supply.


This case study shares how a cloud software development startup maintains both enterprise and open source content for its products by presenting its product and content strategy as a rubric to guide documentation decisions. The rubric is situated within the context of the company's business objectives as well as within the concerns of the field, such as content strategy, usability, accessibility, and discoverability. The rubric is divided into three parts: decisions about the content itself, content operations for lifecycle maintenance, and content access. Practitioners can use the rubric to inform their content strategy across enterprise and open source documentation. Academics might find the rubric helpful as a teaching tool for content strategy courses. Together, practitioners and academics can collaborate on further research to understand how content strategy decisions between enterprise and open source technologies impact the community's ability to use and innovate on the technology, while aligning with an organization's broader strategic goals.


The case applies corporate analysis and valuation to a firm in a serially competitive industry that is undergoing structural shifts in its revenue model, market segments, and overall branding. The apparel and athletic footwear industry of the consumer discretionary sector has suffered due to the decline in brick-and-mortar garment retailers along with a surge in e-commerce offerings. In evaluating the attractiveness of the Under Armour brand, students will consider key industry and company characteristics and trends, before arriving at a recommendation. In completing this assignment, students should be able to: 1) assess the prospects of an industry in both the short-term and medium-term (i.e., 3-5 years out); 2) evaluate the current prospects of a firm, considering global industry and firm-specific factors; 3) determine the actions that a struggling brand in this industry can take to rejuvenate shareholder value; 4) evaluate a firm's potential to grow its market share in international markets in the face of a shifting geopolitical climate; 5) make recommendations regarding the investment attractiveness of the firm. The case is designed for learners in advanced corporate finance. It can be used in capstone undergraduate and graduate level courses.