On the base of literature about slow/controlled release chemical fertilizers, slow/controlled release fertilizers are discriminated and a new method has been adopted for evaluating the longevity of controlled release fertilizer. An introduction is given to the study of long-acting ammonium bicarbonate, zeolite ammonium bicarbonate, slow/controlled release urea, long-acting compound fertilizers. Also, prospects are given for the development of slow/controlled chemical fertilizers in China.


Craniomandibular disorders of traumatic etiology require special documentation techniques to minimize insurance and legal correspondence and to aid in equitable and expeditious claim settlement. The properly documented Narrative Medical Report can effectively meet these requirements while also protecting the integrity of the often scrutinized craniomandibular practice.The article presents an easy to follow outline for the preparation of these comprehensive reports, as well as indicating their specific relevancy in this medico-dental field of treatment. Essential clinical information to be abstracted from patient records is specified and its importance explained. Insurance applications, including Worker's Compensation, Social Security Disability, and Motor Vehicle Casualty/No-Fault Insurance are presented, as are legal applications in civil litigation.The format described will provide a comprehensive, documented record of the patient's condition and the practitioner's treatment protocol, supplying both ins...


With high energy consumption and low energy storage, the brain is highly reliant on continuous cerebral blood flow (CBF) that delivers substrates to maintain proper function, which is compromised after a stroke. The current study explores the overlapping roles played by two important modulators of cerebrovascular tone, rho-kinase (ROCK) and endogenous sex hormones, in the acute CBF responses to a photothrombotic (PT) model of ischemic stroke in ROCK2+/- mice and wild-type (WT) littermates. To remove endogenous hormones, male mice were gonadectomized and female mice were ovariectomized, whereas control ("intact") animals received a sham surgery prior to stroke induction. Intact WT males showed a delayed drop in CBF compared to intact WT females, where maximal CBF drop was observed 48 hours following stroke. Gonadectomy in males did not alter this response, however ovariectomy in females produced a "male-like" response. Intact ROCK2+/- males also showed such phenotypic response, which was not altered by gonadectomy. Alternatively, intact ROCK2+/- females showed a striking difference in CBF values compared to intact WT females, where they displayed higher CBF values immediately post-stroke and also showed a maximal CBF drop 48 hours post-stroke, which was not altered by ovariectomy. Overall, there is a marked sex difference in acute CBF responses to PT stroke, which appears to be mediated by endogenous female sex hormones and ROCK2. This study reveals important sex-differences and the involvement of ROCK2 in acute CBF responses to PT stroke in mice. Significance Statement There are very few mechanistic investigations on disparities between sexes in post-stroke CBF outcome. Rho-kinase, an important regulator of vascular tone, has only been explored in males in terms of its modulation of CBF following stroke. Both rho-kinase and endogenous female sex hormones have a converging role on the regulation of endothelial nitric oxide synthase (eNOS), an important modulator of vascular tone. Rho-kinase is thought to elicit its neuroprotective effects against ischemic stroke through eNOS, however this has never been investigated in both sexes. Elucidating the cellular and molecular bases of sex differences in cerebrovascular pathophysiology is vital for understanding the origins of stroke outcomes, and for designing novel therapeutic strategies to promote functional recovery in both women and men.


The most obvious differences are the buildings. A time traveler from 1994 would be startled by the sight of the West Center, the DiGiorgio Student Center, and Owens Hall on what used to be called "back campus," as well as the Courtyard across the tracks. Carroll Hall and Dalton Hall would be shocks to former business and science majors. Look at that stock ticker! Look at these sparkling labs! And although not new, the recent renovation to Dacus Library make at least the entrance floor a new space.


Abstract Armstrong, LE, Johnson, EC, McKenzie, AL, Ellis, LA, and Williamson, KH. Ultraendurance cycling in a hot environment: thirst, fluid consumption, and water balance. J Strength Cond Res 29(4): 869–876, 2015—The purpose of this field investigation was to identify and clarify factors that may be used by strength and conditioning professionals to help athletes drink adequately but not excessively during endurance exercise. A universal method to accomplish this goal does not exist because the components of water balance (i.e., sweat rate, fluid consumed) are different for each athlete and endurance events differ greatly. Twenty-six male cyclists (mean ± SD; age, 41 ± 8 years; height, 177 ± 7 cm; body mass, 81.85 ± 8.95 kg) completed a summer 164-km road cycling event in 7.0 ± 2.1 hours (range, 4.5–10.4 hours). Thirst ratings, fluid consumed, indices of hydration status, and body water balance (ingested fluid volume − [urine excreted + sweat loss]) were the primary outcome variables. Measurements were taken before the event, at designated aid stations on the course (52, 97, and 136 km), and at the finish line. Body water balance during exercise was not significantly correlated with exercise time on the course, height, body mass, or body mass index. Thirst ratings were not significantly correlated with any variable. We also observed a wide range of total sweat losses (4.9–12.7 L) and total fluid intakes (2.1–10.5 L) during this ultraendurance event. Therefore, we recommend that strength and conditioning professionals develop an individualized drinking plan for each athlete, by calculating sweat rate (milliliter per hour) on the basis of body mass change (in kilograms), during field simulations of competition.


BACKGROUND: The Duffy glycoprotein (Fy) on red blood cells (RBCs) has been hypothesized to promote clearance of inflammatory cytokines, which may play a role in the pathogenesis of vasoocclusion in sickle cell disease (SCD). Persons with the African‐type Fy(a–b–) phenotype—whose RBCs lack expression of Duffy—may less efficiently clear inflammatory cytokines. Therefore, the Duffy‐negative genotype may be associated with more severe disease among patients with SCD.


The frictional contact conditions in a helical spline joint coupling under torsional and axial loads are studied using finite element analyses. Comparisons of spline root torsional stresses are made with photoelastic measurements. Surface contact tractions, relative slip distributions and subsurface localized stress component and equivalent stress distributions are presented for both the external and the internal spline contact surfaces. The work is important as a basis for understanding and predicting the fatigue, contact fatigue, fretting fatigue, wear and fretting wear characteristics of the coupling. A representative test specimen concept is presented which seeks to capture the local contact variable distributions in the spline coupling, with a view to predicting the wear and the contact and fretting fatigue performance of the coupling.


Objective:To observe the clinical curative effect of bile reflux gastritis by the treatment of Pinelliae Decoction for Purging Stomach-Fire. Methods:101 patients with bile reflux gastritis were randomly divided into two groups. Treatment group were given Pinelliae Decoction for Purging Stomach-Fire. Control group were given Omeprazole Enteric-coated Tablets,Domperidone and Sucralfate,6 weeks as one course. Then observed and contrasted the two groups,and analyzed by statistics. Results:There were 21 cases curative,18 cases excellent,9 cases effective and 4 cases ineffective in treatment group. And there were 13 cases were curative,14 cases were excellent,10 cases were effective and 12 cases were ineffective in control group. The two groups had significant difference(P0.05) . Conclusion:Pinelliae Decoction for Purging Stomach-Fire could treat bile reflux gastritis effectively.


Using an algebraic Fourier transform of operators, we develop a method (F-method) to obtain explicit highest weight vectors in the branching laws by differential equations. This article gives a brief explanation of the F-method and its applications to a concrete construction of some natural equivariant operators that arise in parabolic geometry and in automorphic forms.


Abstract The pneumatic springs are frequently used as a machine component. They are mainly used for passive vibration damping with the possibility to regulate the working height of the springs. The paper describes the creation of a mathematical model of a spring controlled thru the PID regulator. At conclusion are summarized the limits of PID control and sketches the future possibility of substituting the PID controller by a neural network.


OBJECTIVES
To measure in-vivo 3D-accuracy of backward-planned partially-guided implant surgery (PGIS) based on dental magnetic resonance imaging (dMRI).

MATERIAL AND METHODS
Thirty-four patients underwent dMRI examinations. Tooth-supported templates were backward planned using standard dental software, 3D-printed, and placed intraorally during a cone-beam computed tomography (CBCT) scan. Treatment plans were verified for surgical viability in CBCT, and implants were placed with guiding of the pilot drill. High-precision impressions were taken after healing. The 3D-accuracy of 41 implants was evaluated by comparing the virtually planned and definitive implant positions with respect to implant entry point, apex, and axis. Deviations from the dMRI-based implant plans were compared with the maximum deviations calculated for a typical single implant.

RESULTS
Twenty-eight implants were placed as planned in dMRI. Evaluation of 3D-accuracy revealed mean deviations (99% confidence intervals) of 1.7±0.9mm (1.2-2.1mm)/2.3±1.1mm (1.8-2.9 mm)/7.1±4.8° (4.6-9.6°) for entry point/apex/axis. The maximum deviations calculated for the typical single implant surpassed the upper bounds of the 99% CIs for the apex and axis, but not for the entry point. In the 13 other implants, dMRI-based implant plans were optimized after CBCT. Here, deviations between the initial dMRI plan and definitive implant position were only in part higher than in the unaltered group (1.9±1.7mm [0.5-3.4mm]/2.5±1.5mm [1.2-3.8mm]/6.8±3.8° [3.6-10.1°] for entry point/apex/axis).

CONCLUSIONS
The 3D-accuracy of dMRI-based PGIS was slightly lower than that previously reported for CBCT-based PGIS. Nonetheless, the values seem promising to facilitate backward-planning without ionizing radiation.


Sir, We report on two patients with steroid-sensitive relapsing nephrotic syndrome, who experienced relapse of their nephro-tic syndrome following initiation of an oral biphosphonate preparation. Case 1. A 42-year-old man had had steroid-dependent nephrotic syndrome from the age of 2 years. Renal biopsies had revealed minimal-change disease at ages 3 and 19 years. After the second biopsy, oral cyclophosphamide was introduced , but later withdrawn because of myelosuppression. Relapses commonly occurred in the early summer and were associated with seasonal rhinitis. The patient was maintained on 7.5 mg of oral prednisolone. A bone densitometry scan indicated hip osteopenia, and an oral biphosphonate preparation (Didronel PMO, Procter and Gamble Pharm) was started (in late summer). He relapsed after 3 weeks with proteinuria increasing from negative dipstick to 2q. He self treated, stopping the biphosphonates and increasing Table 1. Hypoglycaemic treatments Insulin at Oral hypoglycaemics Insulin at Oral hypoglycaemics any time at any time 1 year at 1 year


The present thesis tries to analyze from a constitutional perspective the current educational framework developing art. 27.2 of the Spanish Constitution (CE), from which the research carried out on the faculties and forecasts contained in the constitutional provision itself, including those that supported the subject provided for in the 2006 LOE, Education for Citizenship and Human Rights, and its subsequent repeal by LOMCE of 2013, increasing if possible, the interest for a matter as important in social development as education.

In this context, the juridical-constitutional approach carried out has as its axis a fundamental element, constituted by the analytical decomposition of conformity with the dogmatics of fundamental rights-the study of the right to education, on the one hand, and the higher values Of the legal order, freedom, equality, justice and political pluralism of art. 1.1 CE, on the other, focusing the issue on the content and limits of the rights and freedoms contemplated in art. 27 EC with regard to the suitability of subjects such as Education for Citizenship and Human Rights in its objective of forming a genuine democratic culture among future generations for the safeguard and living of the aforementioned higher values, as well as the supposed conscientious objection raised In its day to the same and still more, now and in the future, the limits to the alleged objection of conscience, in what it does to the education in human rights, from the perspective of the own parents and in connection with the aim pursued by the State and that finally it would happen to establish limits to the arbitrariness of the parents in that sense, questioning what would be the role of the State in this point.

The research work combines exploratory, descriptive and explanatory aspects, as a requirement of the dogmatic-constitutional approach, with the study of judicial decisions adopted as a result of the actual reality that has taken place over it, through resolutions of the Constitutional Court, alongside those of the European Court of Human Rights and the European Committee of Social Rights. All this in order to understand the nature of the problem, if any, and, consequently, to draw the corresponding conclusions and formulate the relevant corrections.

 In any case, it is intended to adopt a constructive critical position, so that taking a position in the concrete aspects that aim at the promotion and safeguard of the implied rights and the respect to the same ones are recognized, in the educational field, with the transcendence which matter requires.


The Internet of Things (IoT) has become a new enabler for collecting real-world observation and measurement data from the physical world. The IoT allows objects with sensing and network capabilities (i.e. Things and devices) to communicate with one another and with other resources (e.g. services) on the digital world. The heterogeneity, dynamicity and ad-hoc nature of underlying data, and services published by most of IoT resources make accessing and processing the data and services a challenging task. The IoT demands distributed, scalable, and efficient indexing solutions for large-scale distributed IoT networks. We describe a novel distributed indexing approach for IoT resources and their published data. The index structure is constructed by encoding the locations of IoT resources into geohashes and then building a quadtree on the minimum bounding box of the geohash representations. This allows to aggregate resources with similar geohashes and reduce the size of the index. We have evaluated our proposed solution on a large-scale dataset and our results show that the proposed approach can efficiently index and enable discovery of the IoT resources with 65% better response time than a centralised approach and with a high success rate (around 90% in the first few attempts).


The "Nationwide System",which is a mode to distribute resourse,can be called "Sports Nationwide System".This system is widely used in the sports field in our country and the strategy is its pracitical scheme whose goal includes winning the game and cultivating the human.However,the disfigurement of this strategy is the strength on winning the game but ignores the importace of cultivating human.There are four pieces of related advice.At first,the sports value should be considered completely.The second,the combiantion between sports and education is very necessary and urgent.The third,the idea of humanity spirit should be put emphasis on.At last,the Olympic spirit should be recognized again.


A large number of modeling activities can be automatic or computer assisted. This automation ensures a more rapid and robust software development. However, engineers must ensure that the models have the properties required for the application. In order to tend towards this requirement, the Domino project (DOMaINs and methodological prOcess) proposes to use the so-called trustworthy Model-Driven Engineering (MDE) components and aims to provide a methodology for the validation and qualification of such components.


Objective To observe the correlation between Th1/Th2 cell model and tumors,and the influence of cytokines on Th1/Th2 paradigm,so to provide basis for the immunotherapy of tumor.Methods Seventy-eight gastric cancer patients(gastric cancer group) and 80 health controls(control group),were enrolled in,enzyme-linked immunospot assay was used to measure Th1,Th2,Th1/Th2 paradigm,the peripheral blood mononuclear cells of 35 cases in control group were cultured and divide into A,B,C group,during the course of culture IL-12+ anti-IL-4 monoclonal antibody(last concentration 4 μg/L and 10 mg/L) and IL-4+anti-γ-IFN monoclonal antibody(last concentration of 20 μg/L and 10 mg/L) were added to A and B group,the C group was not intervened,and the ratio of Th1/Th2 was detected.Results Compared with the control group,Th1 and the ratio of Th1/Th2 in the gastric cancer group apparently decreased,Th2 apparently increased,all P0.05.Compared with the C group,the percentage of Th1 cells and Th1/Th2 ratioin in group A were higher and the percentage of Th2 cells were lower,the percentage of Th1 cells and Th1/Th2 ratio in group B were lower and the percentage of Th2 cells were higher(P0.05).Conclusions Patients with gastric cancer are in the condition of Th2 predominance;IL-12 and anti-IL-4 monoclonal antibody may change this status.


Of all the major groups of the Acarnia it is doubtful if any are more aberrant than the gall mites, and but few show such unity of organization or sameness of habits. Because of this there has been in the past but little evidence upon which to establish any natural affinities between them and any of the other groups, while suggestions as to their origin have been but little more than conjectures.


In this master's thesis a model of algorithmic trading is constructed. The
model aims to create an optimal investment portfolio consisting of a risk-free
asset and a risky asset. The risky asset is in the form of a stock generated
using regime-switching parameters with a Markov chain explaining the state
of the economy. The optimization of the portfolio is carried out under certain
assumptions and reasonable constraints on risk, transaction costs and
amount traded. The constraint on nancial risk is implemented through
the recognized mean-variance criterion, balancing the expected value of the
portfolio against the variance of the portfolio after every time period. The algorithm
is implemented using quadratic programming techniques in Matlab.
By varying parameters of the model a sensitivity analysis is performed. Simulated
scenarios and the behaviour of the algorithm is presented in graphs.
The algorithm is found to be rational and outperforms a static portfolio in
every scenario.


In the CompSOC platform applications are conservatively modeled and analyzed to achieve strict realtime guarantees. Time-non-deterministic system-components are abstracted to their worst-case temporal behavior, resulting in a deterministic Synchronous Dataflow (SDF) model. The individual deterministic models are composed to a system model on which efficient analysis can be performed. An enabling property for ensuring the conservativeness of the analysis performed on the composite-model is the monotonicity of the individual components. Some components in CompSOC have been shown to exhibit non-monotonic behavior, hence need to be treated separately. We propose a framework for the abstraction of non-monotonic components into SDF graphs. The abstraction is compositional in the sense that it allows for abstractions of individual components in a composite-system while preserving the conservativeness of the model. We use the framework to abstract non-monotonic components in the CompSOC communication-channel into a monotonic SDF graphs, which fits well within the CompSOC modeling framework. To complement the modeling of the non-monotonic components of the communication-channel, we provide SDF models of all components of the channel. Our models are either new, or refinements the existing models which provide tighter analysis. Also, we develop a modeling technique that enables modeling of behavior that could not be modeled before. Namely, we model the interference of tasks running on the platform and sharing a buffer or a request-queue under static-order scheduling. This modeling technique can also be applied to general SDF modeling, outside the CompSOC framework.


In this paper we present a polynomial time approximation algorithm for designing a multicast overlay network. The algorithm finds a solution that satisfies capacity and reliability constraints to within a constant factor of optimal, and cost to within alogarithmic factor. The class of networks that our algorithm applies to includes the one used by Akamai Technologies to deliver live media streams over the Internet. In particular, we analyze networks consisting of three stages of nodes. The nodes in the first stage are the sources where live streams originate. A source forwards each of its streams to one or more nodes in the second stage, which are called reflectors. A reflector can split an incoming stream into multiple identical outgoing streams, which are then sent on to nodes in the third and final stage, which are called the sinks. As the packets in a stream trave from one stage to the next, some of them may be lost. The job of a sink is to combine the packets from multiple instances of the same stream (by reordering packets and discarding duplicates) to form a single instance of the stream with minimal loss. We assume that the loss rate between any pair of nodes in the network is known, and that losses between different pairs are independent, but discuss extensions in which some losses may be correlated.


ABSTRACT Drought is an important plant growth-limiting factor. ∆1-Pyrroline-5-carboxylate synthase (P5CS) is a key enzyme closely related to proline biosynthesis under drought stress. A full-length cDNA sequence from the P5CS gene in mulberry (Morus alba), designated MP5CS (GenBank Accession Number KC202259), was cloned. MP5CS was 2190 bp in length, contained a 47-bp 5ʹ-untranslated region (5ʹ-UTR) and a 648-bp 3ʹ-UTR, and encoded 497 amino acids with a predicted molecular weight of 53.92 kDa and an isoelectric point of 9.35. Phylogenetic analysis based on P5CS gene sequences from various species showed that mulberry was closely related to Boehmeria nivea, Malus hupehensis, Gossypium arboreum, and Euonymus japonicas. MP5CS gene expression under drought or salt stress conditions was quantified by quantitative real-time reverse transcription-polymerase chain reaction (RT-qPCR). The results showed that both abiotic stresses caused a significant upregulation in the expression of MP5CS in leaves compared to a normal growth environment. These data provide a better understanding of the molecular basis of signal transduction during stress responses in mulberry trees.


Comparing words where multiple people is involved on defining the meaning of every word is a common situation in different real scenarios such as decision making, natural reasoning, etc. When multiple people express their opinions about a word/lable/concept, then an Interval Type-2 Fuzzy Number can be used to represent uncertainty involved in their opinions, so an important task is how to establish an order of every word involved. To do so, we propose to use the centroid and Yager Index Rank of an Interval Type-2 fuzzy number to establish the order of different words defined by multiple people. We provide an application example and an analysis of the results including some recommendations for practical implementations of both type reduction methods.


The article reviews the book "Capitalism from Below: Markets and Institutional Change in China" by Victor Nee and Sonja Opper.


The invention discloses a touch panel and a manufacturing method of border lines thereof. After two inductive electrode layers are laminated, the border lines of the both are printed, so that the manufacturing procedures can be reduced; the upper inductive electrode layer is provided with a first through hole, a second through hole is formed at the corresponding position of a photoresist after laminating, the border line of the lower electrode layer can still realize electrical connection via the first and second through holes, and the border lines of the upper and lower inductive electrode layers can be simultaneously printed, so that the manufacturing steps can be reduced, then the manufacturing yield is increased, and the production cost is reduced.


This paper describes the possibilities of the 8 inch compatible 3.5 inch micro floppy disk (MFD) with a capacity of 802 K bytes/slde, linear recording density of 13341 bpi and track density of 135 tpi. We were able to achieve such high density recording with two types of media and confirmed the performance of the 8 inch compatible MFD.


Part 1 Welded joints: corrosion fatigue of large welded tubular joints, J. Kerr et al effects of temperature and dissolved oxygen in seawater on the fatigue strength of welded steel joints, H. Ouchi et al corrosion-fatigue tests of welded tubular "T" joints under variable amplitude loading, W.P. Sham et al corrosion-fatigue crack growth rate in a C-Mn steel and in its welded joints in seawater, L. Bertini the effects of stress waveform and frequency on fatigue crack growth rates in a steel immersed in seawater, H. Ouchi et al a quantitative determination of crack closure effects on fatigue properties of cathodically protected steel in seawater, E. Bardal et al the relative severity of natural and synthetic seawaters on the fatigue behaviour of cathodically protected steel, C.C. Monahan and R.M. Hopkins the influence of hydrogenating environments on crack propagation in metals, V.V. Panasyuk and V.S. Kharin the relative importance of crack-tip charging and bulk charging in hydrogen - assisted cracking in aqueous solutions, A. Turnbull et al corrosion fatigue crack propagation in a Duplex stainless steel, M.C. Mayaki and J.E. King polarization experiments with constant K for the examination of competing environmental mechanisms in corrosion fatigue, D.M. Shutter and I.M. Austen corrosion fatigue crack retardation and enhancement and fracture surface reconstruction technique, K. Komai the influence of environment on fatigue crack growth mechanisms, A. Bignonnet et al interactions of temper embrittlement and environment during fatigue of pressure vessel steels, C.A. Hippsley and S.G. Druce effects of environment on the occurence of intergranular facets during fatigue crack propagation in 9Cr-1Mo steel, K. Nishioka and J.F. Knott environment-assisted aerospace fatigue problems in the Netherlands, R.J.H. Wanhill influence of moisture on the crack propagation in A1-Zn-Mg single crystals, H.J. Gudladt et al the corrosion fatigue behaviour of an aluminium-lithium alloy, G.S. Chen and D.J. Duquette the role of surface microcracks in aqueous corrosion fatigue damage, T. Magnin. Part 2 Corrosion fatigue endurance and short crack growth: the corrosion fatigue of a 13 percent chronium turbine blade steel in a condensing steam environment, J. Congelton and T.P. Wilks two-dimensional film opening model for pit generation in the corrosion fatigue crack initiation process of a ferritic stainless steel, Y. Kimura et al the environmental performance of higher strength steels for offshore applications, I.S. Cole et al the initiation and propagation of fatigue cracks under the influence of fretting in 0.64C roping steel wires in air and seawater, M. Takeuchi and R.B. Waterhouse the role of corrosion in the initiation and growth of corrosion fatigue cracks, R.A. Cottis et al influence of cathodic protection on the initiation and growth of small cracks in steel under fatigue loading in seawater, E. Maahn and H.P. Nielsen.


Abstract The article presents an energy approach to studying the effect of a DC electric field on the stability of the domain structure, piezo- and dielectric properties of piezoceramics (Pb0.95Sr0.05)(ZrхTi1-х)O3 (x = 0.45 ÷ 0.60). From the P-E dielectric hysteresis loops, the energy density of the sample W with polarization P in the electric field E is determined. The maximum (critical) value of the energy density Wkr determines the onset of irreversible rearrangement of the domain structure. This is associated with the process of depinning - the stripping of domain walls from the pinning centers in the critical field Ekr .


The excellent combination Qianza 93114 was selected out by crossing GMS 432A with double low line Qianyou 114C. It passed examinations and approved by Guizhou Crops Variety Examination Committee and named Qianyou 11 in 1999. Its highest yield reached 3889.5 kg/ha when average yield was 2435.85 kg/ha in regional test of Guizhou, its yield increased by 17.86% and maturing time was 5d shorter than CK Qinyou 2. Its highest yield reached 3210.0 kg/ha when average yield was 2172.15kg/ha in regional test of Yangtse River, its yield increased by 5.26% and maturing time was 2d shorter than CK Zhongyou 821. Qianyou 11 displayed high yield, stability, medium or early maturing and good suitability. It is suitable to popularize in the area of medium or high altitude and double cropping of rice.


We report real-time voltammetric detection of potential lung cancer biomarkers, namely, interleukin-10 (IL-10) and osteopontin (OPN), using localized silica nanowires as templates, through an electrochemical alkaline phosphatase (AP) based assay. The high surface to volume ratio associated with nanowires enhances the loading of a specific capture antibody toward a particular cancer antigen. An AP enzyme attached to the cancer antigens (IL-10 and OPN) via detector antibodies hydolyses (dephosphorylates) the p-nitrophenyl phosphate substrate to a yellow, water-soluble product, p-nitrophenol (pNP). This was detected in a small test volume of 3 μL, using a microelectrode cell fabricated in Au. The electro-oxidation of pNP occurs between 0.85 and 0.9 V with anodic peak current showing linear dependence with the capture antibody and antigen concentrations, respectively. The detection of IL-10 down to 1 fg/mL in ideal pure solution and 1 pg/mL in clinically relevant samples was achieved reproducibly. Moreover, b...


EM (electromagnetic) signal enhancement is investigated in the presence of interference and thermal noise for both purely and partially polarized cases. Two kinds of local optimal receive polarizations are derived with the constraint of polarization tracks. Finally, formulas derived in this paper are verified by some simulated experiments and results show that they are effective in EM signal enhancement.


This paper studies how firms target the release of complex news to moments with higher market attention. As a natural experiment, we study an institutional discontinuity at 5:30pm every day in the way 8-K filings are released to the public that makes investor attention drop drastically after the threshold. We document a sharp discontinuity in the type of news releases around 5:30pm: news released just before is more complex and gathers more attention than news released just after 5:30pm. Our results are consistent with firms trying to make it easier for investors to understand complex news and hence reduce adverse selection.


The effect of atmosphere on the sintering of CaZrO_3/ZrB_2 composite has been studied in three kind of atmosphere. Thermodynamic analysis has indicated that at high temperature both CaZrO_3 and ZrB_2 thermodgnamic relation would be stable only in Ar atmosphere. The experimental results have verified the reliability of the above thermdgnamic analysis.


where the equations a0x+ b0y + c0 = 0 and a1x+ b1y + c1 = 0 define any two distinct lines. It is known that any conic section can be "generated by the intersection of corresponding lines of two related pencils in a plane" [Som51], p.388. In other words, given two distinct pencils, (a00x+b00y+c00)(1−t)+(a10x+b10y+c10)t = 0 and (a01x+b01y+c01)(1−t)+(a11x+b11y+c11)t = 0, to each value of t corresponds exactly one line from each pencil, and those two lines intersect in a point. The locus of points thus created for −∞ ≤ t ≤ ∞ is a conic section, as illustrated in Figure 18.1. This is reviewed in section 18.2. This chapter examines the extension of that idea to higher degrees. A degree n family of lines intersects a degree m family of lines in a curve of degree m+ n, which is discussed in section 18.3. Section 18.4 shows that any rational curve can be described as the intersection of two families of lines, from which the multiple points and the implicit equation of the curve can be easily obtained. For example, any cubic rational curve can be described as the intersection of a pencil of lines and a quadratic family of lines. The pencil axis lies at the double point of the cubic curve. Section 18.5 discusses the family of lines which is tangent to a given rational curve. Such families of lines are useful for analyzing the singularities of the curve, such as double points, cusps, and inflection points, and also for calculating derivative directions.


Abstract This study investigated the impacts of renin–angiotensin system inhibitors (RASIs) on 2-year clinical outcomes in diabetes and dyslipidemic acute myocardial infarction (AMI) patients after a successful percutaneous coronary intervention (PCI) using newer-generation drug-eluting stents (DESs). A total of 16,997 AMI patients were enrolled, and divided into four groups based on the presence or absence of diabetes and dyslipidemia as follows: diabetes –/dyslipidemia –(group A, 11,132 patients), diabetes +/dyslipidemia – (group B, 3,860 patients), diabetes –/dyslipidemia + (group C, 1,328 patients), and diabetes +/dyslipidemia + (group D, 677 patients). The clinical endpoint was the occurrence of major adverse cardiac events (MACEs), the composite of total death, recurrent myocardial infarction (re-MI), and any repeat revascularization, including target lesion revascularization (TLR), target vessel revascularization (TVR), and non-target vessel revascularization (non-TVR). After RASIs therapy, the cumulative incidences of MACEs (adjusted hazard ratio [aHR], 1.330; 95% confidence interval [CI], 1.022–1.732; P = .034), any repeat revascularization (aHR, 1.584; 95% CI, 1.092–2.298; P = .015), TLR, and TVR were significantly higher in group B than group C. However, the cumulative incidences of all-cause death, cardiac death, re-MI, and non-TVR were similar in groups B and C. In this study, under the newer-generation DESs era, repeat revascularization rate reduction benefit of RASIs therapy in diabetic AMI patients was lesser than that in dyslipidemic AMI patients. However, larger randomized controlled studies are needed to confirm these results in the future.


The orbits with reference to the center of mass of two bodies under mutual inverse square law interaction are obtained by use of the eccentricity vector which is equivalent to the Lenz vector within a numerical factor. The parameters and orientation of the orbits are given.


The invention relates to a wall water pipe adapter joint and belongs to the technical field of water heating appliances. Water pipes in the wall can be lengthened by the joint, and other appliances can be conveniently mounted from the outside. The wall water pipe adapter joint structurally comprises a first joint, the first joint is connected with a second joint, the second joint is connected with a fixing block, the center of the fixing block is provided with a through hole, and the inner wall of the through hole is provided with a thread. The fixing block is provided with a magnet above through a screw hole. The wall water pipe adapter joint is simple in structure, convenient to use and applicable to various places.


In China, high-speed urbanization and urban development led by the market have made public landscape resources being occupied and destroyed. It is necessary to set up an institution of country park to protect open space resources on the lever of controlled planning. It is proposed the developing pattern and strategies choosing of country park from the viewpoint of the conservation of the open space and the public scenery resources, based on the common requirement on development of the city and the suburb. It includes the basic concept, the goals of function, the land gain, the selected location and demarcation, the plan control and management, the guiding policy, and so on. It will promote the country park's sound development and play a positive role in the form and structure of the ecological environment in city.


This paper is concerned with the existence of positive solutions of the nonlinear elliptic problem $-\Delta u+ a(x)u=u^{(N+2)/(N-2)}$, $a(x)\ge 0$, with Neumann boundary conditions in a half-space $\Pi \, \s \, \ {\Bbb R}^N $, $N \ge 3$. The main feature of the problem is a "double" lack of compactness due to the unboundedness of the domain and the presence of the critical Sobolev exponent. The solutions are searched using variational methods, although the functional related to the problem does not satisfy the Palais--Smale compactness condition. We observe that the problem considered has no solutions if $a(x)$ is a positive constant; conditions on $a(x)$ are given sufficient to guarantee existence and multiplicity of positive solutions.


Oxytocin is widely used after child delivery for preventing postpartum haemorrhage. Rather high level of spinal block for for Caesarean section has a disadvantage of frequent arterial hypotension. The aim of our study was to assess maternal circulation after mini-dose (0.5 IU) oxytocin administered before, not after, delivery. Methods. Spinal anaesthesia (L3, hyperbaric 0.5% bupivacaine, 13.5 mg) for Caesarean section was performed in 80 women, randomly divided into study (n=40) and control (n=40) groups. In the study group, oxytocin (0.5 IU, slow intravenous bolus) was administered immediately after anaesthesia performance. In both groups, after delivery the slow oxytocin bolus was administered (4.5 IU in study and 5 IU in control group), then another 5 IU were infused in normal saline over 20-25 min. Results. During anaesthesia, minimal systolic arterial pressure (M±SD) in the study group (107±11 Torr) was significantly (p<0.0001) higher than in the control group (88±10 Torr). Phenylephrine administration before delivery was needed in the study group (28 of 40) significantly (Fisher exact p = 0.0015) more rarely than in the control group (39 of 40); whereas during the whole surgery the difference was insignificant (36 of 40 vs 40 of 40, Fisher exact p = 0.1156). Time to first phenylephrine administration in the study group (10.7±4.0 min) was significantly (p<0.0001) longer than in the control group (1.8±1.0 min). Cumulative phenylephrine dose before delivery (Median: min–max) in the study group (1.25: 1,25–2,5 mg) was significantly (p=0.00424) less than in the control group (5: 2.5–6.25 mg). Cumulative phenylephrine dose during the whole surgery in the study group (3.625: 1.25–7.5 mg) was significantly (p<0.00001) less than in the control group (10: 5–12.5 mg). Our results can be explained by blood mobilization from uterine vasculature. Conclusions. Oxytocin mini-dose (0.5 u), administered at the beginning of spinal anaesthesia for Caesarean section, attenuates arterial hypotension and allows less phenylephrine use.


Background: CT examinations contain opportunistic body composition data with potential prognostic utility. Previous studies have primarily used manual or semi-automated tools to evaluate body composition in patients with colorectal cancer (CRC). Objective: To assess the utility of fully automated body compositions measures derived from pretreatment CT in predicting survival in patients with CRC. Methods: This retrospective study included 1766 patients (mean age, 63.7±14 years; 862 men, 904 women) diagnosed with CRC between January 2001 and September 2020 who underwent pretreatment abdominal CT. A fully automated artificial intelligence-based algorithm was applied to portal venous-phase images to quantify skeletal muscle attenuation at L3 (muscle attenuation), visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) area at L3, and abdominal aorta Agatston score (aortic calcium). The electronic health record was reviewed to identify patients who died of any cause (n=848). ROC analyses and logistic regression analyses were used to identify predictors of survival, with attention to highest- and lowest-risk quartiles. Results: Patients who died, compared with patients who survived, had lower median muscle attenuation (19.2 vs 26.2 HU, p<.001), SAT area (168.4 cm2 vs 197.6 cm2, p<.001), and aortic calcium (620 vs 182, p<.001). Measures with highest 5-year AUCs for predicting survival were muscle attenuation [0.666 and 0.701 in patients without (n=1303) and with (n=463) metastatic disease, respectively] and aortic calcium (0.677 and 0.689, respectively). Combination of muscle attenuation, SAT area, and aortic calcium yielded 5-year AUC of 0.758 and 0.732 in patients without and with metastases, respectively. Risk of death was increased (p<.05) in patients in the lowest quartile for muscle attenuation [hazard ratio (HR)=1.55)] and SAT area (HR=1.81) and in the highest quartile for aortic calcium (HR=1.37), and decreased (p<.05) in patients in the highest quartile for VAT area (HR=0.79) and SAT area (HR=0.76). In 423 patients with available BMI, BMI did not significantly predict death (p=.75). Conclusion: Fully automated CT-based body composition measures including muscle attenuation, SAT area, and aortic calcium, predict survival in patients with CRC. Clinical Impact: Routine pretreatment body composition evaluation could improve initial risk stratification of patients with CRC.


Subtitle: If you want to draw the crowds, you need a star attraction. The Middle East is ripe for foreign investment, and Dubai is leading the way.


The economic impacts of climate change are highly uncertain. Two of the most important uncertainties are the sensitivity of the climate system and the so-called damage functions, which relate climate change to economic costs and benefits. Despite broad awareness of these uncertainties, it is unclear which of them is most important, especially at the regional level. Here we construct regional damage functions, based on two different global damage functions, and apply them to two climate models with vastly different climate sensitivities. We find that uncertainty in both climate sensitivity and aggregate economic damages per degree of warming are of similar importance for the global economic impact of climate change, with the decrease in global economic productivity ranging between 4% and 24% by the end of the century under a high-emission scenario. At the regional level, however, the effects of climate change can vary even more substantially, depending both on a region's initial temperature and the amount of warming it experiences, with some regions gaining in productivity and others losing. The ranges of uncertainty are therefore potentially much larger at a regional level. For example, at the end of the century, under a high-emission scenario, we find that India's productivity decreases between 13% and 57% and Russia's increases between 24% and 74%, while Germany's change in productivity ranges from an increase of 8% to a decrease of 4%. Our findings emphasise the importance of including these uncertainties in estimates of future economic impacts, as they are vital for the resulting impacts and thus policy implications.


The utility model relates to a solar uninterruptible power supply system. The solar uninterruptible power supply system comprises a solar cell array panel and an urban power grid, and is characterized in that the solar cell array panel is connected with a storage battery pack through a storage battery management system and used for charging the storage battery pack, the urban power grid is connected with the storage battery pack through the storage battery management system and used as a backup charging power supply of the storage battery pack, and storage batteries are used for supplying power for a load. The solar uninterruptible power supply system provided by the utility model utilizes the solar cell array panel for charging the storage battery for the continuous use of the load. When the storage battery management system detects that the charging for the solar cell array panel is insufficient, the storage battery management system can automatically switch to the charging by utilizing the urban power grid so as to realize the effect of supplying uninterruptible voltage-stabilizing power for the load.


Abstract Models of track vibration representing the rail as a beam are insufficiently detailed for high frequencies where the rail cross-sectional deformation is significant. A double Timoshenko beam model is developed for vertical vibration analysis at high frequencies. Although simple, this model includes the essential cross-sectional deformation of a rail in vertical vibration at high frequencies. Based on this model, the dispersion relation of propagating waves in a free and a continuously supported rail is studied. Vertical vibration receptances of the rail are calculated using both continuously and discretely supported models. The results show good agreement with an FE model and measurement data in terms of frequency-wavenumber curves, point receptance and vibration decay rate.


This article deals with the features of population settlement within the Ukrainian Black Sea region and its coastal zone. It is emphasized that the problems of coastal resettlement, the factors that determine it, are highlighted in the works of foreign and Ukrainian scientists. The purpose of the work is to find out the features of the population settlement in the region of the Ukrainian Black Sea region. In the studied region, due to the territorial differentiation of economic activity, change in the intensity of economic use of the territory and the population density can be distinguished by the coastal, middle and peripheral economic zones. It was established that the supporting framework of urban settlement in the Ukrainian Black Sea region is characterized by a fairly sparse network, and the settlement process itself is in many respects still in the stage of formation, incompleteness. Unlike the whole region, for the coastal zone, the more prevalent network of urban settlements, which are represented within the coastal zone not only by small and medium, but also large cities (Odesa, Mykolaiv, Kherson), has contributed to the formation of urban agglomerations with wide distribution functions. In the zones of attraction of large cities, a new type of settlement was formed - in fact, suburban. In the Odesa metropolitan area, there are two powerful, fast-developing planning axes - Odesa- Chornomorsk and Odessa-Yuzhne. Seaside-facade linear planning organization agglomeration repeats the restructuring of the territorial structure of Odesa itself, which in the second half of the twentieth century turned from a city with a compact building pattern into a linear city, stretching along the sea bay. In the coastal zone of the Ukrainian Black Sea region, which occupies one third of the region's area, live 65.0% of the total number of inhabitants of the region. The density of urban settlement network here is 1.5-2.0 times higher than the average indicators of the region, urban processes in the coastal zone are characterized by greater intensity. Small cities of the coastal zone in genetic typing are mainly seaport cities, urban-type settlements, and resort and recreation in character. More than 40% of the rural population is concentrated in the coastal regions and tends to agglomeration, which, in its turn, causes a steady flow of  the settlement network from areas remote from the centers of economic activity. In the last 5 years, the demographic situation, both  in the region as a whole and in the coastal zone, has deteriorated significantly, and here, as in other districts, depopulation is evident. The prospects for the development of the coastal resettlement system are directly related to the further intensification of maritime and recreational activities, and, first of all, with the development of recreational, tourist and port infrastructure.


Simple Summary In the present study, we exposed mice to aberrant lighting system and noticed anxiety-like behavior. These symptoms were ameliorated by oral administration of curcumin. The study was carried out on the animals for three weeks in dim light at night (dLAN) and complete darkness (DD), monitoring the body weight, daily food intake, anxiety-like behavior, and expression of the period (PER1) gene. The exposure to dim light at night was found to significantly enhance the anxiety-like behavior and increased the body weight possibly through altered metabolism in mice. In contrast, exposure to DD caused increased anxiety but no significant difference in the body weight. Moreover, the expression of the PER1 gene involved in sleep was also found to be decreased in the aberrant light conditions (dLAN and DD). Although the treatment of curcumin had no effect on the body weight, it had ameliorated the anxiety-like behavior possibly by modulating the expression of the PER1 gene. Thus, the alteration in the light/dark cycle has negative influences on body weight, affecting even the emotional quotient. This study identifies the risk factors associated with aberrant lighting conditions in laboratory animal and ameliorative effects of curcumin. Abstract In the modern research field, laboratory animals are constantly kept under artificial lighting conditions. However, recent studies have shown the effect of artificial light on animal behavior and metabolism. In the present study on mice, following three weeks of housing in dim light at night (dLAN; 5lux) and complete darkness (DD; 0lux), we monitored the effect on body weight, daily food intake, anxiety-like behavior by employing the open field test, and expression of the period (PER1) gene. We also studied the effect of oral administration of different concentrations of curcumin (50, 100, and 150 mg/kg) for three weeks in the same mice and monitored these parameters. The exposure to dLAN had significantly increased the anxiety-like behavior and body weight possibly through the altered metabolism in mice, whereas exposure to DD caused increased anxiety but no significant difference in weight gain. Moreover, the expression of the PER1 gene involved in sleep was also found to be decreased in the aberrant light conditions (dLAN and DD). Although the treatment of curcumin had no effect on body weight, it ameliorated the anxiety-like behavior possibly by modulating the expression of the PER1 gene. Thus, alteration in the light/dark cycle had a negative effect on laboratory animals on the body weight and emotions of animals. The present study identifies the risk factors associated with artificial lighting systems on the behavior of laboratory animals and the ameliorative effects of curcumin, with a focus on anxiety-like behavior.


The present invention relates to a traditional Chinese medicine for the treatment of synovitis, which is composed of the following raw material components in parts by weight ratio: Angelica, Coix seed, Gorgon Puhuang, herb, Poria, fresh white skin, Lygodium, yams , Alisma, Digupi, Cnidium, Menispermaceae, castor seed, Astragalus, Codonopsis, Kochia scoparia 10 to 25 parts. Synovitis therapeutic medicine of the present invention, can fully adjust the body's immune function, improvement of microcirculation, the spleen can be cold, chills chubi, diuresis Shenshi, swelling and pain, various drugs, treating the symptoms, the patient joint function is restored, through local fumigation, heat, so that the drug directly to lesions, and achieved good therapeutic effect. Synovitis treatment has efficacy, side effects of small, easy to use, and low price.


4 Redman M, Regan F, Contreras M: A prospective study of the incidence of red call allo-immunisation following transfusion. Vox Sang 1996; 71:216–220 5 Stainsby D, Knowles SM, Milkins C, Jones H, Cohen H: Can haemolytic transfusion reactions be avoided by better laboratory practice? Vox Sang 2005; 89 (Suppl 1):14 6 Poole GD, Evans RG, Voak D, Scott ML, Chapman JF, Phillips PK: Medical Devices Agency evaluation report – six systems for the detection of red cell antibodies. HMSO MDA/96/14. Copies available from HMSO, St Clements House, 2/16 Colgate, Norwich NR13 1PD, UK, or from http://www.mhra.gov.uk


Sir, This acknowledges the receipt of your letter of the 21st infant; in return to which I have sent you, for my lord Anson's information, an account of the irregularity of the tides, having taken particular notice of them by the Lys, a French ship, having broke from her moorings three times in that week.


The dynamics of wheat aphid natural enemy community in different intercropping patterns (wheat-oilseed rape intercropping, wheat-garlic intercropping and monoculture) were investigated with biodiversity measures including species richness (S), dominance (D), Shannon's Index (H′), and evenness (E). It was showed that the species richness of natural enemies in wheat-oilseed rape intercropping pattern was almost higher than those of the other two patterns during the investigation period. However, the other two patterns were similar in the whole stage of investigation. The dominant species of natural enemies among the three planting patterns were different at the beginning of investigation, but in the mid-and late-stage were Aphidius avenae. During investigation, diversity index of natural enemies in wheat-oilseed rape intercropping pattern was the highest. After May 8, the dominance of A. avenae in wheat-oilseed rape intercropping pattern was the lowest with significant difference compared with the other two patterns, and the index of evenness was the highest. It is concluded that in wheat-oilseed rape intercropping pattern, with higher species richness and higher stability community of natural enemies, it could control wheat aphid infection especially in early wheat filling stage, and there was no obvious effect of wheat-garlic intercropping on community structure and dynamics of wheat aphid natural enemies.


Aim: This study is going to assess the prevalance of prolonged grief diagnoses and it will evaluate the severity of the symptoms of depression, anxiety and complicated grief two months after a loved one is lost. We also intend to study which variables associated with the risk of grief could be more decisive when diagnosing it, its symptoms and the consequent emotional distress. Method: A total of 66 families of patients in the Palliative Care Unit (PCU) at Hospital San Cecilio in Granada have been evaluated. Measurements were taken two months after the death. This investigation has explored the existing emotional distress using the following questionnaires: Beck Depression Inventory (BDI-II), Beck Anxiety Inventory (BAI), Inventory of Complicated Grief (ICG) and Prolongued Grief Disorder (PG-12). Results: The results show that 33.3% and 21.21% of the sufferers had high levels of depression and clinical anxiety two months after the death. The prevalence of prolongued grief diagnoses, according to the PG-12, is 10.6% and 53.03% of the participants showed symptoms of complicated grief according to the ICG. Additionally, statistically significant differences are found in the sufferers with and without a prolongued grief diagnosis and scores in the ICG and BDI-II. The family's financial situation is linked to the presence of symptoms of anxiety and depression and complicated grief, with the most determining variable being the risk of grief. Finally, the greater the age of the deceased and the longer the time spent in the PCU is linked to fewer symptoms of grief. However, important links have been found between the sufferers who have experienced stressful critical events prior to losing their loved one, with symptoms of depression, anxiety and complicated grief. Conclusions: The high numbers of cases of symptoms of complicated grief and levels of anxiety and clinical depression two months after a death suggests that early interventions should be carried out in those individuals with greater vulnerability.


Introduction: Anemia is one of the nutritional problems in adolescents, especially at the Morosi Health Center with a prevalence of anemia in June 2022 of 27.95% who have an Hb of 9-10 g/dl, 9.67% have a Hb of 7-8 g/dl and 1.07% Hb< 7 g/dl. The purpose of this study was to determine the effect of giving Fe tablets to increase hemoglobin in young women in the mining area of Morosi District.
Methods: This type of research is pre-experimental, with a one-group pre-test-post-test design. The population is part of young women in WonuaMorini Village, Besu Village, and Mendikonu Village, amounting to 72 people taken using the Proporsionatestratifed random Sampling technique. Hb level data was obtained by easy touch meter. The data were analyzed using the Wilcoxon sign rank test.
Results: Showed the average Hb level before intervention was 11,38 g/dl and after intervention was 11,38 g/dl. The second week 11,68 g/dl after the intervention. The third week after the intervention was 12.86 g/dl and the fourth week after the intervention was 12.86 g/dl.The results of the Wilcoxon sign rank test obtained a p-value (0.000) < (0.05).
Conclusion: There is no effect of giving Fe tablets in the first and there was an effect of giving Fe tablets in the Second to fourth weeks of increasing hemoglobin in young women in the mining area of Morosi District. Research suggests that young women routinely consume blood-added tablets once a week.


Contents List of Figures and Tables Acknowledgements PART I: CONCEPTS, THEORY AND METHOD Constitutional Anomie Meta-Constitutional Orientations Old Labour, New Labour, 'Blair Paradox' Democratic Analysis PART II: DIMENSIONS OF REFORM V1 Party System V2 Cabinets V3 Executive-Legislature Relationship V4 Electoral system V5 Interest groups V6 Federal-Unitary V7 Unicameralism-Bicameralism. V8 Constitutional Amendment V9 Judicial Review V10 Central Bank PART III: ANALYSIS AND IMPLICATIONS Bi-Constitutionalism Democratic Drift


Globalisation poses significant challenges, but the EU has the economic power to use the process to its benefit. While technological innovation may be disrupting the traditional understanding of labour and the free market, and of international cooperation more generally, it represents an opportunity for the EU to become a global leader. The EU should continue its efforts to provide citizens with the skills they need for the future and to promote research and development. By remaining competitive and ensuring a stable geographical environment, the EU will be able to shape globalisation to its benefit.


Abstract World annual petroleum consumption and vegetable oil production is about 4.018 and 0.107 billion tons, respectively. Vegetable oils from bio-renewable oil seeds can be used when mixed with diesel fuels. Vegetable oils can be used as fuels for diesel engines, but their viscosities are much higher than usual diesel fuel and require modifications of the engines. Different ways have been considered to reduce the viscosity of vegetable oils, such as dilution, microemulsification, pyrolysis, catalytic cracking, and transesterification. Compared with transesterification, pyrolysis process has more advantages. The liquid fuel produced from pyrolysis has similar chemical components to conventional petroleum diesel fuel. Vegetable oils can be converted to a maximum of liquid and gaseous hydrocarbons by pyrolysis, decarboxylation, deoxygenation, and catalytic cracking processes.


A series of iron(III) ethylenebis(2‐hydroxypheny1)glycine [Fe(EHPG)]‐ derivatives have been examined for their role as paramagnetic hepatobiliary contrast agents for magnetic resonance (MR) imaging. The 5‐substituted complexes, Fe(5‐Me‐EHPG)−, Fe(5‐Cl‐EHPG)−, and Fe(5‐Br‐EHPG)−, have been compared to the parent compound in rat bio‐distribution and MR imaging studies; correlative in vitro parameters for the complexes, including octanol‐buffer partition coefficients and albumin binding affinity, have also been obtained. The three new derivatives exhibited higher degrees of lipophilicity and albumin binding affinity and varying degrees of improvement in liver‐to‐blood and bile‐to‐liver concentration ratios measured at 30 min postinjection. The 5‐C1 complex had the best overall performance in terms of these tissue ratios as well as in terms of total biliary excretion. Sequential MR images of rats after administration of the complexes revealed subtle pharmacokinetic differences among the derivatives and, in general, correlated well with and complemented the biodistribution results. This study points to the sensitivity of hepatocellular uptake and excretion to simple chemical modifications and, moreover, demonstrates the importance of screening multiple derivatives to select optimal hepatobiliary MR imaging agents. © 1987 Academic press, Inc.


This article proposes a novel interaction force estimation scheme capable of estimating the interaction forces for industrial robots with high precision in the absence of force sensors. Specifically, we first establish the dynamic model of a class of industrial robots via model identification methods. Furthermore, a high-order finite-time observer (HOFTO) is established to estimate the interaction forces, where HOFTO serves as an interaction force observer and is designed to accurately estimate external time-varying interaction forces. In addition, we strictly analyze the stability of our approach in two different cases, endowing HOFTO with reliable estimation abilities in broader applications. Subsequently, we integrate the estimated force information into the applications of force control frameworks (e.g., collision detection and impedance control). Several evaluations on a real 6-axes robot demonstrate the effectiveness of the proposed approach.


Polyamidoamine (PAMAM) dendrimers up to the third generation were grown for the first time on the surface of a large-pore (18 nm) Davisil silica support. The supported dendrimers of generations 0, 1, 2 and 3 were phosphinomethylated and complexed with rhodium. All the generations were found to be very active for the hydroformylation of olefins. The hydroformylation of 1-octene was accomplished with a turnover frequency of 1700 h - 1 at 70°C. The G(1) material was found to be the most active when the different generations were compared at 50% conversion at 70°C.


In this article,strategic performance are divided into5 kinds of performance: financial performance,customer performance,internal operation performance,human resource performance and society responsibility performance.The article puts forward a new index system of strategic performance evaluation.This article presents a new method of evaluating the enterprise's strategic performance based on BP's neural network.According to the index system that has been already set up,the article designs the BP neural network(BPNN) imitation model.With the method of computation,the paper uses the NNT based on MATLAB to make network design and computation.Through the training and testing of lots of studying samples,the imitation model has been established.In the end,the paper proves the accuracy and feasibility of the method with an example.


Confirmatory factor analysis was used to determine the factor structure of the Wechsler Intelligence Scale for Children–Fourth Edition (WISC-IV) scores of 297 children referred to a children's hospital in the Southwestern United States. Results support previous findings that indicate the WISC-IV is best represented by a direct hierarchical (bifactor) model including four first-order factors and one general intelligence factor. In this sample, the general intelligence factor accounted for 50% of the total variance and 76% of the common variance. Of the first-order factors, the Verbal Comprehension factor accounted for the most total (5.6%) and common (8.4%) variance. Furthermore, the general intelligence factor accounted for more variance in each subtest than did its respective first-order factor and it was the only factor that exhibited adequate measurement precision (ωh = .87). These findings support previous recommendations that WISC-IV interpretations should focus on the general intelligence factor over first-order factors.


This chapter follows on from the design, planning, performance and use of clay in the construction of fills and in the quarrying of clay as a mineral for use in construction presented in Chapter 10 by considering the practical aspects involved in the excavation, loading, transportation, modification, placement and compaction of clays in construction and mineral extraction projects. The various operations involved in the excavation, loading, transportation, modification, placement and compaction of materials in or on the ground are termed 'earthmoving'. The structures that are formed as the result of these operations are known as 'earthworks'. Some earthworks are constructed to carry out a particular function, such as cuttings and embankments for roads or railways, whereas others, such as quarries and borrow pits, are formed as a consequence of the removal of materials for other uses. Some quarries may be re-used as landfill sites for the disposal of waste materials. In recent times, landfill sites have become engineered structures in their own right and quarries in clay are especially valued owing to the low permeability of the underlying clays, which serve to limit the movement of leachate or liquid wastes away from the site. In earthmoving practice, clays may be considered as those materials containing predominantly clay- and silt-size materials (i.e. fine-grained soils); however they also include materials that contain sufficient fine material that cause them to behave as fined-grained soils and weak rocks, including clayey sands, glacial till and some highly to completely weathered rocks. They may vary considerably


There is a perceived dichotomy between the aim of increased product lifetimes and recyclability, promoted by sustainable development practitioners, and the reduced product lifecycle and cost-effective production methods demanded by the marketplace. To address these issues, this paper presents an assessment of the available digital enterprise technologies for the concurrent design of sustainable products and the associated manufacturing systems. Some of the tools and techniques which are available to increase the sustainability and manufacturability of products through innovative manufacturing methodologies are investigated.


Summary A new congenital hemorrhagic diathesis, which is due to the presence of a circulating inhibitor against factor IX, simulating a hemophilia B, is described. It is demonstrated, that the inhibitor becomes much less efficient when the factor VUI-concentration decreases. A hypothesis is given which should explain the role of factor VIII in the inhibition process.


activities, interests, cinema-going, reading and various aspects of family life in different localities, at different seasons and with viewers who have owned sets for different periods of time. Overall, this volume is a mine of information on the numerous topics examined, and the chapters dealing with problems of research methodology are particularly cogent in their treatment of difficulties of sampling, of appropriately matching " viewers" and " non-viewers"; of clarifying the matters to be investigated, the items of information to be sought, and the methods to be used for gathering and tabulating the data. Of special interest in these respects, to the reviewer at least, are those chapters (17, 21) which describe his Stable Correlate technique and how he deals with" extraneous influences ". and those chapters (20 to 29) which deal with the social impact of television. This is a book which can be warmly recommended to students and research workers in social science, and to all those interested in the management or the " impact .. of television. F. W. MITCHELL, University of Otago.


Despite all the software systems we have seen, both in IEEE Software's columns and through our professional experience, periodically, something happens in the world of software engineering that really takes us by surprise. The last time we were in this position was after the revelation of software "cheats," that is, algorithms deliberately introduced into a system with the specific purpose of misleading the general public and certification agencies on the nature of system emissions.8 This time, we feel that we must comment on the equally startling revelations emerging about the interactions among software, management, and requirements in the sad case of the two Boeing 737 MAX crashes.


We report on the dispersion of high frequency (GHz) acoustic excitations in three‐dimensional colloidal crystalline or amorphous assemblies of sub‐micron particles in different matrices by Brillouin light scattering (BLS) in order to explore the phononic and elastic properties of nanostructured materials. In air, we record eigenmodes of the individual particles, which are shown to be independent from the crystallinity and the composition of the sample but sensitively depend on the particle architecture (e.g core/shell silica/PMMA, hollow spheres) and their mechanical properties at nanoscale. In fluid matrices, the dispersion relations are recorded. We demonstrate the occurence of two hypersonic phononic band gaps of different nature. One is a Bragg gap appearing only in crystalline samples, the other one is a particle resonance‐induced hybridization gap, which appears in crystalline samples along with the Bragg gap and alone in amorphous samples. Furthermore, we investigate the influence of filling fracti...


To observe the clinical effects of "Zhangyi Powder" in the treatment of senile cataract,70 cases were classified into treatment group with 35 cases and 66 eyes treated with "Zhangyi Powder" and control group with 35 cases and 62 eyes treated with Catalin Eye Drops.They all were treated for one month,once a week.The eyesight,conjunctiva,cornea,lens and symptoms were measured.Results:the treatment group obtained better effects than the control group;in treatment group,the average eyesight increased (P 0.05 )14 days after treatment;the eyesight in treatment group improved more significantly than that in control group 28 days after treatment (P0.05);the blurred vision and dry eyes were relieved more greatly in treatment group than in control group (P0.05).


Cherenkov-excited luminescence scanned imaging (CELSI) has been proposed for radiation-dose determination in medical physics due to its high spatial-resolution over centimeters of tissue. However, dense line-scanning illumination in typical CELSI is time-cost owing to the mechanical movement of the leaves in multi leaf collimator (MLC), resulting into increased radiation exposure. As a result, a scanningless Cherenkov luminescence imaging modality is herein proposed through structuring epi-illumination with MLC-based Hadamard-patterns, which utilizes a reduced radiation does by limiting illumination patterns, extremely shortening the sampling process. In order to effectively reconstruct unknowns from the resultant underdetermined linear system with sparse samplings, a compressed sensing-based reconstruction methodology with l1-norm regularization is adopted. Numerical and phantom experiments show that the proposed methodology achieves the same image quality as the traditional CELSI does.


This paper presents an optimization method for detecting SIFT points (Scale-invariant feature transform), by using a GPU parallelization, taking advantage of multiple cores of it, to divide the processes using the API's CUDA. The goal is to accelerate the computation time, which is a critical variable for the entire process of key-point's detection. The strategy used is based on two assumptions, the load balance and distribution of calculation. Each thread will perform the operations required for calculating SIFT and obtain the necessary descriptors according to an appropriate threshold. Parallelizing the process of assignment of orientation, which consists of the accumulation of all the orientations concerning a region of a key-point, assigned to each pixel in the window a thread, centered on the location of a key point, was worked inside SIFT. The tests were performed with a Notebook with Core 2 Duo 2.2GHz, 3GB of RAM and a GeForce 8600GT VGA (32 Cores) 512MB. The results obtained show that performance is achieved in terms of speed of the order 42.5 millisecond on average, considering all tests and all resolutions worked (320x240, 480x360, 640x480, 800x600, 1024x768, 1280x960), where the parallelization of SIFT, shows no significant loss of key points, compared to the sequential version.


The rotational speeds of stars in the disc of a spiral galaxy are virtually independent of the distances of the stars from the centre of the galaxy. In common parlance, the stellar speed versus distance plot known as a galactic rotation curve is by observation typically nearly flat. This observation provides strong evidence that most galactic matter is dark, i.e. undetectable through luminosity measurements. This article is intended to serve the pedagogical purpose of using the dark matter problem as the basis of exercises accessible to university students. Gauss's law is first used to explain why luminosity measurements lead to the prediction of incorrect speed distributions for disc stars in spiral galaxies. The question of how mass can be distributed within a galaxy to enable flat rotation curves is then considered. Gauss's law concisely answers this question for an idealized galaxy with spherical symmetry. For an idealized planar galaxy with circular symmetry, constructing and evaluating an integral for the gravitational field as a function of distance from the centre of the galaxy provides the answer to the question.


Knowledge economy now governs every aspect of our lives. Knowledge is the basic currency of this knowledge economy. Equipped with exclusive rights, intellectual properties (IP) are now destined to play the crucial role in this knowledge economy. In this respect, non-practicing entities (NPEs) are deemed to be the legitimate players of this new economy. The 1st-generation NPEs are characterized as entities independent of the manufacturers, whereas the 2nd-generation NPEs and defensive NPEs (i.e., patent aggregators) are heavily influenced by the manufactures, for the manufacturers now play the role of the investors or members of the NPEs. NPEs are here to stay! Despite the resistance form the IT industry in the US, the Senate has recently passed the bill which is essentially benign to the NPEs. In addition, Chief Judge Rader of the Court of Appeals of the Federal Circuit has recently declared that his Court will judge the patents not by the nature of the patent holders but by their quality. In every respect, there is no sign that the rights of the patentees are to be significantly eroded in the near future. It then is manifest that this country as a whole should jump onto the wagon and strive to efficiently generate IP, to protect IP in the major industrial countries, and to utilize IP to its full value.


The accumulation of radiation dose (α, β, γ) by a mineral with time, due to initial presence of uranium, (U) being in disequilibrium, is illustrated in a family of curves of dose versus time for the past one million years. A summary of revised dose-rate is also given.


A systematic analysis is carried out on the current situation of the implementation of Curriculum Standards of Physical Education and Health in rural middle schools of state-level poverty-stricken counties through using the method of survey, literature, interview and random sampling. Factors affecting the implementation are found as follows: the investment into facilities like venues and equipment is insufficient, the qualification of teachers need improving, the lack of understanding and recognition of Curriculum Standards of Physical Education and Health still exists, the importance attached to physical education is far from enough. Based on the problems, some countermeasures are put forward from the perspective of management by combining the reality of the economic and educational development in Hunan and the essence of the new curriculum standards.


Capacity development is one of the IMF's core activities. Its impact is monitored through a Results-Based Management framework. Using for the first time the resulting dataset, the paper investigates how the likelihood of achieving targeted outcomes correlates with macroeconomic conditions and project-specific characteristics. Results indicate a positive correlation with per capita GDP growth and the involvement of resident advisors and regional centers. Results also confirm lower chances of achieving targeted outcomes for fragile, conflict-affected, and small states as well as in complex projects. These findings inform Fund CD strategy, prioritization and delivery to help member countries achieve better outcomes. IMF Working Papers describe research in progress by the author(s) and are published to elicit comments and to encourage debate. The views expressed in IMF Working Papers are those of the author(s) and do not necessarily represent the views of the IMF, its Executive Board, or IMF management.


Most processing plants use automatic samplers to extract ore aliquots along a producing shift. These aliquots are combined into a sample normally sent to lab analysis. The sampler used in the extraction of an aliquot from a continuous flow of ore, i.e. a belt conveyor is required to be both precise and accurate. Surprisingly, not all commercial automatic samplers exhibit these two mandatory propelties. Consequently, it is recommended the development of a procedure able to check sample assays reproducibility obtained using a given sampling protocol. This paper uses the Gy's sampling theory to evaluate coal quality control practices at a washing plant using an automatic sampler extracting coal increments from the ROM feeding belt conveyor. Gy's theory provides the means to establish the precision limits for a given sampling protocol. Various ore properties are required to be determined in combination with sample mass and mass of the lot sampled. All this inf01lllation leads to the definition of the precision limit. The precision limit obtained was checked via an experiment mimicking what happens in situations where both miner and consumer use the same and appropriate sampling practices. The experiment demonstrates that sampling theory precision limits were valid if unbiased samplers are used by both parties, i.e. miner and consumer.


Stored wheat flour samples purchased from Jazan local markets in Saudi Arabia were checked for the presence of pests, insect and fungal species. The insects existing in the flour were separated and identified as red flour beetle Tribolium castaneum and from 60 individuals (dead bodies) inspected, 17 individuals exhibited abnormal deformation, decomposition and or superficial fungal growths. Incubation of the dead insects' bodies resulted in emergence of fungal growth on the surface of these bodies. Nine fungal species that belonged to eight fungal genera were isolated. Results indicate that Beauveria bassiana and Verticillium lecanii were the most dominant fungi among those isolated from T. castaneum growing in flour followed by Sporothrix sp., Hirsutella versicolor, Granulomanus sp., modern Rhizoctonia solani, Moelleriella sp., Aspergillus fumigatus and A. flavus.

 Key words: Stored wheat flour, Tribolium castaneum, fungi, Jazan, Saudi Arabia.


Abstract Feeding development of asp Aspius aspius larvae was studied during rearing in Lake Maroz (north Poland) illuminated cages. The initial rearing occurred under controlled conditions in a hatchery. After four and half weeks, reared fish (total length 14.8 mm) were transported to cages maintained in a lake. The initial stocking density was about 8 830 fish per cage. All experiments were replicated three times. Fish were fed Zooplankton collected during night with a light placed over the cages. During the seven weeks rearing period in lake cages survival was relatively high (over 72%). The observed feeding development pattern was as follow: rotifers, nauplii, copepodites, adult Copepoda, then adult Cladocera. The largest asp larvae also ate imago forms of insects.


Belgoprocess is momentarily in the process of purchasing its fifth NDA-system. Measurement systems are, although based on general designs, not from the shelf items but tailormade sophisticated and highly automated devices. It is obvious that such a project cannot be carried out by solely a NDA team, but needs a multifunctional team. This team combines NDA expertise with experts in civil works, electrical and mechanical engineering, procurement, IT, safety and legal administration. From less positive experiences in the past, Belgoprocess learned a lot and has now a systematic in place. This systematic structures the project from definition of requirements to operation, a two to three year process. This paper defines the phases of a NDA project and gives for each phase some do's and don'ts. A second subject is the writing and handling of the vast but needed and required documentation. It gives a brief overview of the over thirty documents and files needed. The described, integrated and formal approach reduces the risk of failing projects, systems not meeting the expectations or denied qualification. It puts clear agreements in place, smoothening the relationship between company, supplier and authorities.Copyright © 2007 by ASME


A ballistic trajectory in air of a powered projectile where the thrust always balances the drag is termed as a pseudovacuum trajectory. For a solid-fuel-ramjet (SFRJ)-powered gun-launched projectile this trajectory can be achieved by the control of engine mass-e ow rate, either by a bypass control of inlet air or by a regression rate controloffuel. Based on one-dimensional considerations,theproceduresfora preliminary designofthepropulsion system for an SFRJ-assisted gun-launched projectile and the methods to calculate the control requirements are presented. Using these, typical cone gurations of SFRJ suitable for 155-mm gun-launched projectiles are analyzed for different launch angles. The results indicate that the control requirements by either method are minimal and thus, demonstrate the self-throttling characteristics of SFRJ.


Plasmablastic lymphoma is an aggressive non-Hodgkin lymphoma predominantly seen in adult patients. Only eight cases of plasmablastic lymphoma in children have been published to date. In this report, we present an additional two cases. The first patient was a 9-year-old girl presenting with a nasal mass, while the second was a 15-year-old girl with swelling of the right side of the face and proptosis. Both patients were HIV-positive.


Figure S1: Rescaled friction forces Ff/N and number of HBsNHB/N between 2 parallel N=10 polyglycines as a function of the number of fixed alpha carbon atoms on the non-pulled peptide chains,Nfix (open-circles). The moving peptide chain is pulled with a ve locity of V = 1 m/s by a spring that is attached to a single amino acid. The data po int indicated by a filled triangle is obtained in a different scenario where both peptides are pul l d in opposite directions with velocities −V/2 andV/2. The results forFf/N andNHB/N are in good agreement if the number of fixed alpha carbon atoms on the non-pulled peptide chains does not exceedNfix = 4. ∗To whom correspondence should be addressed †Department of Chemistry, University of North Carolina at Ch apel Hill, NC 27514, USA ‡Freie Universität Berlin, Fachbereich Physik, 14195 Berli n, Germany


This Coastal and Hydraulics Engineering technical note (CHETN) details a Geographic Information Systems (GIS) methodology to produce advanced lidar-derived datasets for use in a coastal erosion vulnerability analysis conducted by the US Army Corps of Engineers (USACE) and other federal partners for the Great Lakes Restoration Initiative (GLRI).


The article presents theoretical considerations on the character of websites and tries to define the term 'publication' or 'documentation'. The author elaborates on such points which can be used in the discussion about this issue as: obligatory norms, scientific achievements, practice of other countries and uniform substantial lists of legislative acts.


New way to effectively capture CO₂ in coal fired power plant is the combustion of coal using oxy-fuel technology. Combustion characteristics of Minco sub-bituminous coal at oxy-fuel conditions using TGA and drop tube furnace (DTF) were included activation energy about the char burnout, volatile yield and combustion efficiency of raw coal, the porosity of pyrolyzed char and fusion temperature of by-product ash. TGA result shows that the effect of CO₂ on combustion kinetics reduces activation energy by approximately 7 kJ/㏖ at air oxygen level(21% O₂) and decreases the burning time by approximately 16%. The results from DTF indicated similar combustion efficiency under O₂/CO₂ and O₂/N₂ atmospheres for equivalent O₂ concentration whereas high combustion efficiency under O₂/N₂ than O₂/CO₂ was obtained for high temperature of more than 1,100℃. Overall coal burning rate under O₂/CO₂ is decreased due to the lower rate of oxygen diffusion into coal surface through the CO₂ rich boundary layer. By-product ash produced under O₂/CO₂ and O₂/N₂ was similar IDT in irrelevant to O₂ concentration and atmospheres gas during the coal combustion.


Lighting apparatus for medical diagnostic instruments, with at least one LED (36) via a circuit means (50) is connectable to a voltage source, optionally from a battery unit (70) or a battery unit (74) is formed, wherein a first contact device (60) for a compound of the battery unit (70) and a second contact means (64) for connecting the battery unit (74) to the circuit means (50) are provided, wherein said circuit means comprises a circuit electronics (52) connected to the first contact device (60) and with the second contact means (64) is connected and with the LED (36) is connected, wherein the electronic circuitry (52) is designed and configured to perform a battery operation mode when the first contact device (60) (with the battery unit 70) is connected, and performs a battery mode of operation if the second contact device (64) with the is connected battery unit (74), characterized, in that is the electronic circuitry (52) adapted and configured to, in the battery operation mode - applying a first battery mode of operation, power to the LED (36) when the battery voltage exceeds a first battery threshold value, - applying a second battery mode of operation, power to the LED (36), which is lower than the first battery operational mode power when the battery voltage falls below the first battery threshold and is higher than a second battery threshold which is lower than the first battery -threshold, and - does not apply a power to the LED (36) when the battery voltage exceeds the first threshold by a certain amount below, and in the battery operation mode - applying a first cordless mode of operation power to the LED (36) when the battery voltage exceeds a first battery threshold and ...


The cluster NGC 6530 has been found by Walker to contain stars that have not yet reached the main sequence. In a colormagnitude diagram these stars are located above the main sequence as defined by field stars. Theoretically, there is no upper limit to the color index of a young star in the contracting stage. This is in contrast with the definite limits found observationally in the intrinsic colors of the red dwarfs and giants. It is of interest, therefore, to study the colors and spectra of the reddest stars in young clusters. A program with this aim has been initiated at the Warner and Swasey Observatory. The present paper gives some of the results obtained for NGC 6530. The object of this study was to find the red stars in the vicinity of NGC 6530, and to determine whether at least some of these are associated with the cluster. It is difficult in a survey of this nature to prevent the inclusion of background or foreground red stars. Distant giant M stars occur in large numbers in the clearer areas surrounding M 8. However, as Walker points out, the cluster appears to have as a backdrop a dense cloud of interstellar material. By limiting the study to areas within the limits of the cloud, the distant M giants may be excluded. The probable number of foreground M dwarfs can be estimated from density considerations, and is negligible. The selection of the very red stars was made by comparison of two pairs of direct photographs taken with the Burrell telescope at the Nassau Astronomical Station. Each pair consisted of a photovisual plate (Kodak 103a-D plus Schott G 11 filter) and an infrared one (Kodak I-N plus Schott RG 8 filter). The plates were examined with a blink comparator, and independent surveys were made by the two authors. The present study was limited to the two circular areas shown in Figure 1, which extend over 350 and 75 square minutes of arc.


Natural adsorbents as low-cost materials have been proved efficient for water remediation and have significant capacity for the removal of certain chemicals from wastewater. The present investigation aimed to use Citrullus colocynthis seeds (CCSs) and peels (CCPs) as an efficient natural adsorbent for methylene blue (MB) dye in an aqueous solution. The examined biosorbents were characterized using surface area analyzer (BET), scanning electron microscope (SEM), thermogravimetric analyzer (TGA) and Fourier transform infra-red (FT-IR) spectroscopy. Batch adsorption experiments were conducted to optimize the main factors influencing the biosorption process. The equilibrium data for the adsorption of MB by CCSs were best described by the Langmuir isotherm followed by the Freundlich adsorption isotherms, while the equilibrium data for MB adsorption by CCPs were well fitted by the Langmuir isotherm followed by the Temkin isotherm. Under optimum conditions, the maximum biosorption capacity and removal efficiency were 18.832 mg g−1 and 98.00% for MB-CCSs and 4.480 mg g−1 and 91.43% for MB-CCPs. Kinetic studies revealed that MB adsorption onto CCSs obeys pseudo-first order kinetic model (K1 = 0.0274 min−1), while MB adsorption onto CCPs follows the pseudo-second order kinetic model (K2 = 0.0177 g mg−1 min−1). Thermodynamic studies revealed that the MB biosorption by CCSs was endothermic and a spontaneous process in nature associated with a rise in randomness, but the MB adsorption by CCPs was exothermic and a spontaneous process only at room temperature with a decline in disorder. Based on the obtained results, CCSs and CCPSs can be utilized as efficient, natural biosorbents, and CCSs is promising since it showed the highest removal percentage and adsorption capacity of MB dye.


Most of the research effort on image-based place recognition is designed for urban environments. In bucolic environments such as natural scenes with low texture and little semantic content, the main challenge is to handle the variations in visual appearance across time such as illumination, weather, vegetation state or viewpoints. The nature of the variations is different and this leads to a different approach to describing a bucolic scene. We introduce a global image description computed from its semantic and topological information. It is built from the wavelet transforms of the image's semantic edges. Matching two images is then equivalent to matching their semantic edge transforms. This method reaches state-of-the-art image retrieval performance on two multi-season environment-monitoring datasets: the CMU-Seasons and the Symphony Lake dataset. It also generalizes to urban scenes on which it is on par with the current baselines NetVLAD and DELF.


This paper investigates an out-of-autoclave (OoA), embedded-resistive heating method to precisely control the bondline temperature when curing high strength adhesives for joining composite adherends. A challenge with OoA methods is that nonuniform heat loss, e.g., due to substructures that act as local heat sinks, can lead to nonuniform temperatures in the bondline, which in turn, can result in uneven curing, residual stresses, and potentially weak joints. The main contribution of this work is to apply a voltage pattern at the boundary of the embedded heater to control the distribution of the electrical power at the interior bondline, and thereby reduce temperature variations. Additionally, this work devises an empirical model (that can be applied when material parameters and models are not readily available) to predict the desired power generation, and to design the embedded heater and voltage pattern that minimizes the bondline temperature variation. The technique is demonstrated experimentally for bonding a single-lap joint, and the maximum temperature variation in the bond area was reduced by five times from 31.6 °C to 6.0 °C.


In article the contents and practical use of forms and methods of medical and pedagogical control of physical training of students, standard ordered for application in educational institutions of the country is analyzed, and also prospects of improvement of the maintenance of a pedagogical component of this control at the expense of use of potential of means of anthropometrical control of individual physical development and a functional training of the students which technique was developed by a group of authors of teachers and the staff of the Tula State University are considered.


Significance Translation termination is a crucial process during protein synthesis. Class I release factors (RFs) are in charge of recognizing stop codons and consequently hydrolyzing the peptidyl-tRNA at the ribosomal P site. High-resolution crystal- and cryo-EM structures of RFs bound to the ribosome revealed a network of potential interactions that is formed between the mRNA and RFs; however, it remained enigmatic which interactions are critical for accurate stop codon recognition and peptide release. By using chemically modified stop codon nucleotides, the importance and the contribution of single hydrogen bonds to stop codon recognition was investigated. This approach revealed a detailed picture of chemical groups defining a stop codon and contributing to the discrimination against sense codons during prokaryotic and eukaryotic translation termination. Termination of protein synthesis is triggered by the recognition of a stop codon at the ribosomal A site and is mediated by class I release factors (RFs). Whereas in bacteria, RF1 and RF2 promote termination at UAA/UAG and UAA/UGA stop codons, respectively, eukaryotes only depend on one RF (eRF1) to initiate peptide release at all three stop codons. Based on several structural as well as biochemical studies, interactions between mRNA, tRNA, and rRNA have been proposed to be required for stop codon recognition. In this study, the influence of these interactions was investigated by using chemically modified stop codons. Single functional groups within stop codon nucleotides were substituted to weaken or completely eliminate specific interactions between the respective mRNA and RFs. Our findings provide detailed insight into the recognition mode of bacterial and eukaryotic RFs, thereby revealing the chemical groups of nucleotides that define the identity of stop codons and provide the means to discriminate against noncognate stop codons or UGG sense codons.


Coase (1960) claimed that in the zero costs world, it would not matter for the allocation of resources which of two disputants were awarded the relevant property rights. Block (1977) disputed this, on the ground that it assumed that both parties would have the wherewithal with which to make the relevant bribe. Demsetz (1977) maintained that Block (1977) failed to reckon with Coase's (1960) explicit assumption of no wealth effects. Block (1995) disputed this claim of Demsetz's (1977), claiming the Coase (1960) anticipated no such thing. The next round in this debate was Demsetz (1997) who reiterated his position, followed by Block (2000) in a response to Demsetz (1997). Brook (2007) mostly takes Demsetz's (1977, 1997) side of this ongoing discussion. The present paper is a rejoinder to Brook (2007), supporting Block (1997, 1995, 2000).