The paper describes a procedure for automatic selection of symptoms accompanying the break in the synchronous motor armature winding coils. This procedure, called the feature selection, leads to choosing from a full set of features describing the problem, such a subset that would allow the best distinguishing between healthy and damaged states. As the features the spectra components amplitudes of the motor current signals were used. The full spectra of current signals are considered as the multidimensional feature spaces and their subspaces are tested. Particular subspaces are chosen with the aid of genetic algorithm and their goodness is tested using Mahalanobis distance measure. The algorithm searches for such a subspaces for which this distance is the greatest. The algorithm is very efficient and, as it was confirmed by research, leads to good results. The proposed technique is successfully applied in many other fields of science and technology, including medical diagnostics.


On-die memories, which are traditionally implemented by SRAM, stop functioning properly when the supply voltage is scaled down aggressively; hence, embedded DRAMs (eDRAMs) are used instead. Opportunistic refreshing was proved to eliminate the performance loss incurred by the eDRAM refreshing must. We show here that Gain-Cell eDRAM (GCeDRAM) supplemented with opportunistic refreshing consumes significantly smaller power and energy than SRAM. Analysis supported by hardware simulations demonstrate that the same design point achieves maximum performance and minimum energy. Replacement of the data memory in the ultra-low power processor PULPino from SRAM to opportunistically refreshed GCeDRAM yielded 30% energy savings in the memory, which translated into 7% savings in the entire processor.


Rats were exposed to 300 ppm m‐xylene vapour for 1 or 2 weeks, 6 h daily, 5 days a week. One group was simultaneously given disulfiram in the drinking water (53 μmol kg−1, daily). The disulfiram treatment inhibited propionaldehyde dehydrogenase; such inhibition did not occur when m‐methylbenzaldehyde (i.e., the aldehyde of m‐xylene metabolism) was used as the substrate. Gastric gavage with higher drug doses (0.5 g kg−1, administered one or three times) confirmed this finding. Intermittent inhalation exposure to m‐xylene for 2 weeks lowered the non‐protein sulphhydryl group content in liver and increased the activities of microsomal NADPH‐cytochrome c reductase, 7‐ethoxycoumarin O‐deethylase and UDP‐glucuronosyltransferase in liver. Concomitantly, the oxidation of m‐xylene in vitro was also enhanced. Combined exposure to the solvent and the drug somewhat inhibited the increases in the hepatic drug metabolism and in the rate of microsomal xylene oxidation in vitro which m‐xylene had induced, whereas the renal drug metabolism remained almost unaffected. Despite the changes in the monooxygenase, the solvent burden in the perirenal fat remained comparable. The significance of impaired aldehyde metabolism in m‐xylene toxicity could not be confirmed in male Wistar rats at the above exposure levels.


The second of a three-part series on the effects of smoking on sexual, reproductive and child health. Part One, published last month, summarised the effects of smoking on sexual health and fertility. Part three will look at the effects of smoking on other aspects of reproductive health, and on child health.


Low-cost remotely operated vehicles (LCROV's), targeted in the early 1980's for offshore oil inspection tasks, have been deployed by scientists for in-situ observation and photography. Use of the free-swimming camera/vehicle systems represents a safe, economical departure from diver and manned submersible systems that have dominated undersea research since the 1960's. The basic vehicle system can be used as an alternative to divers or for diver assist to depths of 300 meters. Vehicles equipped with adapted or newly designed instrumentation and tools can fly as multi-instrument arrays for precise imaging, sampling, instrument positioning, inspection, and retrieval.


This paper deals with the theory of point interactions for the one-dimensional Schrödinger equation. The familiar example of the δ-potential V(x) = gδ(x−x0), for which the transfer matrix across the singularity (point transfer matrix) is given by is extended to cover cases in which the transfer matrix M(z) is dependent on the (complex) spectral parameter z, and which can be obtained as limits of transfer matrices across finite intervals for sequences of approximating potentials Vn. The case of point transfer matrices polynomially dependent on z is treated in detail, with a complete characterization of such matrices and a proof of their factorization as products of point transfer matrices linearly dependent on z. The theory presented here has applications to the study of point interactions in quantum mechanics, and provides new classes of point interactions which can be obtained as limiting cases of regular potentials.


A new temperature dependent apparent bandgap narrowing model, appropriate for low temperature device simulations is proposed. The model is based on the decomposition of apparent bandgap narrowing in equilibrium into different contributions at 300K and on the theoretical temperature dependence of each phenomenon. Specific heavy doping effects that can be important at low temperatures are discussed. Temperature dependence of apparent bandgap narrowing in equilibrium is more significant at high concentration of ionized impurities, where apparent bandgap narrowing decreases with decreasing temperature, as a consequence of temperature dependent degeneracy


When an earthquake happens, the image-based techniques are influential tools for detection and classification of damaged buildings. Obtaining precise and exhaustive information about the condition and state of damaged buildings after an earthquake is basis of disaster management. Today's using satellite imageries such Quickbird is becoming more significant data for disaster management. In this paper, a method for detecting and classifying of damaged buildings using satellite imageries and digital map is proposed. In this method after extracting buildings position from digital map, they are located in the pre-event and post-event images of Bam earthquake. After generating features, genetic algorithm applied for obtaining optimal features. For classification, Adaptive boosting is used and compared with neural networks. Experimental results show that total accuracy of adaptive boosting for detecting and classifying of collapsed buildings is about 84 percent.


PURPOSE: Hand-held snow melting mat and carpet are provided, which can create clean environment by preventing dirty environment caused by icing or stacking of snow. CONSTITUTION: Hand-held snow melting mat and carpet comprise: a rectangular mat(10) settled in the floor or wall; a resistance wire heating cable(20) which is formed into zigzag under the mat, emits heat, and has resistivity against fluid; aluminum foil(30) covering the resistance wire heating cable; and a controller(40) which is connected to the resistance wire heating cable and has resistivity against fluid.


Large-scale distributed PV access changes the distribution of currents in the distribution grid, and the random volatility of its output is the main cause of voltage fluctuation. In order to comprehensively reveal the impact of large-scale distributed photovoltaic penetration on voltage in distribution network, this paper analyzes the theoretical mechanism of PV access to the distribution network on voltage deviation and voltage fluctuation, building a simulation model of the distribution network and PV based on Matlab/simulink, and analyzing the impact of various factors such as grid-connected location, access mode, PV output correlation, and weather conditions on voltage. In addition, for the voltage fluctuations under different weather conditions, the envelopes of the instantaneous values of nodal voltages are extracted by finding the wave crests and cubic spline interpolation, using the Hilbert-Huang transform (HHT) method, and the envelope signals are processed by empirical mode decomposition (EMD) and the Hilbert transform, to realize a detailed analysis of the modulation signals of the voltage fluctuations. The results show that large-scale distributed PV access significantly increases the voltage level of distribution network, and PV using single-phase grid-connected access will cause a large effect on the node voltage three-phase unbalance. The magnitude of voltage fluctuations increases with increasing PV output correlation. Distribution network node voltage with PV output changes occur random fluctuations, node voltage amplitude modulation effect by multiple low-frequency signals, the more drastic the change in illumination radiance, the greater the change in the amplitude of the modulating wave, the larger the voltage fluctuation.


To study 12 bacterial species involved in weaning pig diseases,a total of 107 23S rRNA gene sequences were obtained from GenBank and our laboratory sequencing data.They were phylogeneticly analyzed by DNASTAR software.The phylogenetic grouping result out of 12 species representatives were correlated with Bergey's Manual of Determinative Bacteriology and http://www.wiki.cn/wiki/,as well as 16S rRNA gene phylogenetic analysis of the bacteria.Therefore the universal primers from conservative regions of the 23S rRNA gene and the species specific probes from its variable regions could be designed.The relevant unknown bacterial species in the specimen is then determined based on the 23S rDNA fragments amplification and hybridization with selected probes.


This research aims to analyze the comparison of the financial performance of BUMN Islamic Commercial Banks and Non BUMN Islamic Commercial Banks on the variables of Risk Profile, Good Corporate Governance, Earnings, and Capital (RGEC) for the 2017-2020 period represented by the ratio of NPF, FDR, BOPO, GCG, ROA, ROE, and CAR. The results of this research show that of the 7 ratios analyzed, there are 5 ratios with significant differences between the financial performance of BUMN Islamic Commercial Banks and Non BUMN Islamic Commercial Banks during the 2017-2020 period, namely FDR, BOPO, GCG, ROA, and ROE. While the NPF ratio, CAR, and RGEC Composite Rating there is no significant difference between the financial performance of BUMN Islamic Commercial Banks and Non BUMN Islamic Commercial Banks during the 2017-2020 period. The last analysis on the consolidated financial performance assessment of all RGEC variables shows that the performance of BUMN Islamic Commercial Banks is not better than the performance of Non BUMN Islamic Commercial Banks where the average composite value for 4 years is the performance of BUMN Islamic Commercial Banks (80%), smaller than the composite value of the performance of Non BUMN Islamic Commercial Banks (86%).


ABSTRACT: We examined 82 fresh fecal samples from American White Pelican (Pelecanus erythrorhynchos) at San Pablo Autopan, Toluca Valley, central Mexico, December 2021 to April 2022. Eggs of Contracaecum spp. were observed in 100%, Capillaria spp. in two (2.5%), Strongyloides spp. in eight (9.7%), and coccidial oocysts in 12 (15%).


Purpose
The purpose of this study is to examine the impact of ethical leadership on negative feedback-seeking behavior (NFSB). In addition, it sought to investigate the mediating role of psychological safety and job involvement in this relationship.

Design/methodology/approach
The sample for this study comprised 238 primary and secondary school teachers who were selected from three private sector schools operating in Pakistan. Structural equation modeling was used to test the research hypotheses.

Findings
Results revealed that as expected, psychological safety and job involvement fully mediated the effects of ethical leadership on NFSB.

Originality/value
To the best of the author's knowledge, this is the first study that has empirically established a connection between ethical leadership and NFSB. Furthermore, it uncovers two distinct mechanisms in the form of psychological safety and job involvement through which ethical leadership can influence NFSB.


Abstract : To what degree is the formulation of the United States National Security Strategy subject to the influence of "hyphenated Americans," has the foreign policy of the U S already been influenced by ethnic factors, and will the influence of hyphenated Americans increase or diminish in the 21st century? To answer these questions and understand the implications for the United States the reader must understand several factors, including, the origins of the United States, the trends in immigration, recent advances in technology, and societal pressures for assimilation that have occurred since the nation's founding.


The article is devoted to the conceptual modelling of state management of the innovation process in modern conditions. The construction of the conceptual model included the identification and operational description of the goals of state management of the innovation process, the definition of significant controlled inputs to this process from the state, as well as possible types and tools of control actions on them. The article substantiates the roles of the following key parameters of the state impact model on the innovation process: the national innovation resource, the institutional, legal, economic, socio-psychological conditions for its formation, and the state order for socially significant innovations. It is shown that the main and most effective control actions of the social state on the innovation process should be aimed at reducing the cost and providing wide access to modern forms of education at all levels based on digitalization and artificial intelligence. The author substantiates the need for a closer link between the formation of scientific and technological schools of the country and the specifics of its natural resource base, as well as the institutionalization of economic responsibility of experts with state funding of socially significant innovations. The presentation of this conceptual model can become a material for discussion, which will facilitate the transition from conceptual to numerical and simulation modelling of the process under consideration. The article was prepared based on the results of research carried out at the expense of budgetary funds on the state order of the Financial University


In this study, dicyandiamide (DCDA) modified polystyrene (PS) resin beads decorated with nano-Fe3O4 (Fe3O4-PS-DCDA hybrids) were prepared by co-precipitation method. The Fe3O4-PS-DCDA hybrids were characterized by scanning electron microscopy (SEM), Fourier transform-infrared (FT-IR) spectroscopy, X-ray diffraction (XRD) spectroscopy, X-ray photoelectron spectroscopy (XPS), nitrogen adsorption/desorption isotherms, and vibrating sample magnetometer (VSM). Meanwhile, the adsorption property of Fe3O4-PS-DCDA hybrids for Hg(II) in aqueous solution was investigated by batch methods. The results show that the nano-Fe3O4 decorated on the outer surface and interior of DCDA modified PS resin beads (PS-DCDA) is nanoparticles and nanorods, respectively. The saturation magnetization (Ms) of the Fe3O4-PS-DCDA hybrids is 0.70 emu/g, which is enough to ensure the convenient magnetic separation. The adsorption kinetics of the hybrids for Hg(II) accorded with the pseudo-second-order model and the adsorption isotherms followed the Freundlich equation. POLYM. COMPOS., 2016. © 2016 Society of Plastics Engineers


This paper introduces the structure,the functions and the basic operating principle of K9F1280U0M with 64M*8bit NAND flash memory produced by Samsung Corporation,studies its interface with the low-power MCU MSP430,and provides the schematic diagram of hardware interface and the implementation of software programming.


Solar energetic particles (SEPs), one of the main causes of particle radiation in interplanetary space, can disrupt radio communication, induce spacecraft failures and change the heating and cooling rates in the atmosphere among others. To investigate the impact of SEPs and more specifically solar proton events (SPEs), we established a cutoff latitude database based on energetic particle data from Combined X‐ray Dosimeters (CXDs) on board the Global Positioning System (GPS) spacecraft. Introducing a novel normalization method involving proton fluxes from the Geostationary Operational Environmental Satellites enabled us to include the CXD data from its introduction (2001) onwards. The database contains 5714 cutoff latitudes divided over six energies between 18 and 115 MeV which occur during 58 SPEs from 2001 to 2015. Based on the database, a cutoff latitude parameterization as a function of solar wind dynamic pressure and geomagnetic indices Kp and Dst is created for each energy. Moreover, comparisons to previous studies on energetic particle data from the Polar Orbiting Environmental Satellites have been performed to put the GPS data into perspective. A 1–2° poleward offset is found for the GPS based cutoff latitude models, for which several causes are discussed. Furthermore, the limitation of GPS data to geomagnetic latitudes above 60° should be considered. All in all, the usage of the long time span of GPS data in this study combined with its recent release (2016) opens up a new range of studies involving GPS energetic particle data such as investigating long‐term trends with respect to our solar cycle or magnetospheric trends.


The biomass and seasonal variability of all groups of planktonic organisms was investigated in saline meromictic Mahoney Lake (British Columbia, Canada). After ice-break, meltwater formed a stable surface layer which resulted in steep vertical gradients of temperature, salinity, and oxygen concentration. This secondary chemocline persisted until August when it was detected at 4m depth. Pronounced vertical differences were also observed for heterotrophic flagellates, ciliates, rotifers, calanoid copepods, and growth rates of chemotrophic bacterioplankton. No strong correlation between the different components of the microbial loop was found, but phytoplankton primary production and ciliates numbers were tightly correlated (r 2 = 0.649, p<0.001). Compared to phytoplankton biomass (<200 mgC. m -2 ), the biomass of bacterioplankton in the epilimnion measured in autumn was more than one order of magnitude higher (up to 5,650 mgC. m -2 ) and chemoheterotrophic bacterial production exceeded photosynthesis by a factor of 7.1. By comparison, the biomasses of flagellates and ciliates remained very low throughout the year (maxima, 5.52 and 3.4 mgC. m -2 ) whereas that of the calanoid copepod Diaptomus connexus rose to unexpected high levels (681 mgC. m -2 ). parallel to the increase in biomass of aerobic chemoheterotrophic bacteria. Calanoid copepods represent the highest trophic level in the planktonic food web of this fishless lake. Taken together our results indicated an unusual pattern of carbon flow in Mahoney Lake. Maximum rates of carbon transfer.


This paper proposes a solution for supporting end users in configuring Virtual Reality environments by exploiting reusable templates created by experts. We identify the roles participating in the environment development and the means for delegating part of the behaviour definition to the end users. We focus in particular on enabling end users to define the environment behaviour. The solution exploits a taxonomy defining common virtual objects having high-level actions for specifying event-condition-action rules readable as natural language sentences. End users exploit such actions to define the environment behaviour. We report on a proof-of-concept implementation of the proposed approach, on its validation through two different case studies (virtual shop and museum), and on evaluating the approach with expert users.


The correlations and nature of the internal, thermo-electro-mechanical fields of ferroelectrics were investigated. The thermodynamic equation and the equation of the properties of matter which are satisfied by the internal, electric and mechanical fields were given. For the reduced, thermo-electric coupling case, the conclusion that the greater the latent heat is, the greater the polarization is, was obtained. And we found that the effect of volume and shape, combined with the electric effect, is connected to that of the changes of the distances and orientations among particles causing the changes of the distributions and movements of charges or vice versa.


Introduction: Dental implants are used to replace missing teeth. Smoking tobacco is considered as risk factor in implant success rate. Materials and method: In present study 50 patients were divided into equal two groups: Group I with smokers and Group II with nonsmokers. After considering the inclusion and exclusion criteria, implant was placed by slandered aseptic procedure in both the groups. The success of implant was assessed clinically for mobility f implant and radiographically for marginal bone loss at 3, 6 and 9 months after implant placement. The difference in the parameters at each recall interval was examined and recorded. The obtained data for both the groups were statistically analyzed. Results: There was marginal loss around dental implant and implant mobility was observed in smoker at 3,6 and 9 months. The finding was statistically significant in group I. Conclusion: There is definite correlation of smoking on failure of dental implants.


This paper presents an ultrasonic transducer modeling with very high-speed integrated circuit (VHSIC) hardware description language-analog and mixed signal (VHDL-AMS) IEEE 1076.1 integrated in a global measurement cell modeling dedicated to biological tissue ultrasound characterization. Usual modeling of ultrasonic transducers is based on electrical analogy and is not simulated in the global measurement environment. The ultrasonic transducer modeling proposed is simulated with a nonlinear acoustic load and electronic excitation. The nonlinear B/A parameter is used to characterize a medium with a comparative method. The measurement cell is composed of two piezoelectric ceramic transducers, which are implemented with Redwood's electric scheme. The analyzed medium is placed between the transducers and modeled to take into account the nonlinear propagation with the B/A parameter. The usual transmission line model has been modified to take into account the nonlinear propagation for a one-dimensional (1-D) wave. Simulations of the transducer pulse response and electrical impedance show a VHDL-AMS model that is in good agreement with measurement and compared to the usual personal computer simulation program with integrated circuit emphasis results simulations. Results obtained by simulation of mediums (blood, milk, liver, and human fat tissue) showed good agreement between modeling and experimental measurement, and a maximum error of about 12.5% for B/A measurement-simulation


The face of science and engineering has been changing with the recent growth in computer architecture. This growth is so important and robust that it is dramatically reshaping relationships among people and organizations and providing a foundation for understanding and learning of intelligent behavior in living and engineered systems. Is this growth beneficial to our society, these are such questions of the general public which are due to the lack of education concerning rapidly advancing technologies. This paper attempts to present an overview of Artificial Intelligence (AI). A generally accepted theory that ―machine will do and think like humans more in the future‖ is the concept behind AI. Brief literature of different aspects by which AI is achieved like expert system, knowledge based systems (knowledge engineering), neural networks, fuzzy logic, Neuro-fuzzy logic and fuzzy expert system, is included in order to have a clear understanding of AI. Along with this the different applications of AI, has been included in this paper. It is concluded that extensive ongoing research in the field of AI gives an idea that in near future a day will come when human beings and machines will merge into cyborgs or cybernetic organisms that are more capable and powerful than either. This idea is called transhumanism. KeywordsArtificial Intelligence; Expert System; Neural Network; Fuzzy Logic; Neuro-fuzzy logic.


This paper discusses the yield analysis of the thin film wiring layers fabricated on the 127 mm multichip glass ceramic modules (MCM-D), currently used on the IBM Enterprise System/9000/sup TM/ family of computer processors. To select a suitable polyimide (PI) for the thin film wiring layer, modules were fabricated with either the BTDA-APB or the PMDA-ODA polyimide. By keeping all other processing parameters and structures the same, the wiring layers fabricated with the PMDA-ODA polyimide exhibited significantly better yield than those made of the BTDA-APB PI. The yield loss in the modules fabricated with the BTDA-APB PI occurred during thermal processing, where some of the transmission lines fabricated atop the PI were found cracked. Further investigations indicate that, during lift-off processing, the presence of a small contaminant, such as a fiber, metal flake, a particle, or polishing scratches can expose the PI to the hot N-methylpyrollidinone (NMP) solvent. Depending on the polyimide used for thin film processing, the diffusion and swelling of the PI by the low molecular weight organic solvent can potentially produce significant damage to the polyimide/Cu wiring structure and the consequent yield loss of the modules due to line opens. The magnitude of the damage was found to depend on the rate of solvent diffusion, process temperature, lift-off time and the amount of PI swelling during processing.


Quantum communication through spin chains has been extensively investigated. In this scenario, state transfer through linearly arranged spins connected by uniform nearest-neighbor couplings qualifies as a natural choice, with minimal control requirements. However, quantum states usually cannot be perfectly transferred through a uniformly coupled chain due to the dispersion of the chain. Here, we propose an effective quantum control technique to realize almost exact state transfer (AEST) in a quantum spin chain. The strategy is to add a leakage elimination operator Hamiltonian to the evolution, which implements a sequence of pulse control acting on a perfect state transfer subspace. By using the one-component Feshbach PQ partitioning technique, we obtain the conditions over the required pulses. AEST through a spin chain can then be obtained under a suitable pulse intensity and duration.


This essay briefly introduces the production of twin skeg block in section and the positioning installation of shaft bracket in drydock,that is,implementing synchronous installation of skeg block and shaft both by accuracy control of grand assembly of twin skeg block and technology of drydock embarkation and installation and by specified bracket base to ensure shafting optical alignment so that the installation diffculties of twin skeg block in drydock can be solved.


With the help of digital terrain model (DTM) techniques, this paper presents the integrated methods for highway survey and design. The methods include obtaining dispersed points automatically or manually, creating DTM (Triangulated Irregular Network) and computer aided design for highway alignments. Based on several different projects, this paper delivered a valuable conclusion which should be useful for other projects.


This paper presents a strategy that banks can use to help "unbanked" households, those who do not have accounts at deposit institutions, to join the mainstream financial system. The strategy seeks to help these households build savings and improve their credit-risk profiles in order to lower their cost of payment services, eliminate a common source of personal stress, and gain access to lower-cost sources of credit. The strategy calls on participating banks to open special branch offices, called "outlets," that are conveniently located for lower-income households. In addition to traditional consumer banking products, the outlets should offer five non-traditional services:


Although paternity test has been widely used as a modern technology,but the related ethical problems have long been neglected.In the first part,the author proposes the ethical problems from the relationship between technology and ethics within paternity test.In the second part,the author tries to elucidate original reasons for paternity test from the different ethical infrastructures between western and eastern societies.In the last part,the author reflects on the ethical problems of paternity test,and believes that paternity test urgently needs to be guided by the scientific outlook on development which means viewing man as the central element or purpose of the universe.In the present situation of paternity test,we need to consolidate the protection for the juveniles in the paternity test,and we need to reconstruct the new ethics of socialism with Chinese characteristics to build a harmonious society according to the principle of scientific outlook on development.


The behavior of a non-conductive quasi-planar lipid membrane in an electrolyte and in a static (dc) electric field is investigated theoretically in the nonlinear (Poisson–Boltzmann) regime. Electrostatic effects due to charges in the membrane lipids and in the double layers lead to corrections to the membrane elastic moduli, which are analyzed here. We show that, especially in the low salt limit, (i) the electrostatic contribution to the membrane's surface tension due to the Debye layers crosses over from a quadratic behavior in the externally applied voltage to a linear voltage regime, and (ii) the contribution to the membrane's bending modulus due to the Debye layers saturates for high voltages. Nevertheless, the membrane undulation instability due to an effectively negative surface tension predicted by the linear Debye–Hückel theory is shown to persist in the nonlinear, high-voltage regime.


The structural and morphological characteristics of InAs/GaAs radial nanowire heterostructures were investigated using transmission electron microscopy. It has been found that the radial growth of InAs was preferentially initiated on the {112}A sidewalls of GaAs nanowires. This preferential deposition leads to extraordinarily asymmetric InAs/GaAs radial nanowire heterostructures. Such formation of radial nanowire heterostructures provides an opportunity to engineer hierarchical nanostructures, which further widens the potential applications of semiconductor nanostructures.


"Corpus linguistics represents, in the study of legal language, a method with various practical manifestations with the role of allowing a thorough analysis of the particularities of specialized legal discourse. The present work represents a theoretical and practical study that approaches from an interdisciplinary perspective the connection between corpus analysis and legal discourse, emphasizing concrete techniques for using the linguistic mechanisms used in corpus linguistics. The constitution and selection of a corpus for the purpose of pragmatic analysis requires a documentation effort on the part of researchers concerned with the thorough research of the legal discourse, using a series of established as well as innovative methods, as well as the computer programs and databases used to collect the analyzed data. At the same time, the socio-pragmatic framework in which the legal discourse is drawn up and captured has an important influence on the applicable legal norms, but also on the drafting methods of legal documents. Therefore, the analysis of the corpus represents an important step in the deciphering of legal texts both at the national and at the European level, the particular character of the legal discourse taking shape also through the linguistic mechanisms characteristic of this type of discourse, approaching a multidisciplinary plan."


A taxonomic study of the longidorid nematodes collected in the islands of Sao Tome and Principe in the Guinea Gulf, revealed the presence of one species of Longidorus and eight species of Xiphinema. L. laevicapitatus Williams and X. longicaudatum Luc were the most common and widespread, occurring in both islands. X. brasiliense Lordello was found only in Prigrave;ncipe and X. ifacolum Luc only in Sao Tome. X. setariae Luc and X. vulgare Tarjan, although less common than X. setariae, occurred both in Sao Tome and Principe. The male of X. longicaudatum is reported for the first time. Two new species are described: X. dihysterum found in Sao Tome and X. insulanum found only on the small island Das Cabras, north east of Sao Tome. The first resembles X. longicaudatum from which it differs in its didelphic female reproductive system; the second is similar to X. vulgare. A ninth species is not named because only one female was found.


Timing is an important consideration in B2B marketing. B2B companies can use proven lead nuturing, pull marketing and social media techniques to stay in touch with prospects until they are ready to engage in the sales process.


Abstract
Objective: To identify a journal subset that publishes reports of high quality studies and reviews relating to age-specific clinical specialties, such as pediatrics and geriatrics.

Design: Handsearch of 172 journals using explicit criteria to determine methodologic quality for generating evidence for clinical practice.

Main outcome measure: Frequency of high quality articles and their top yielding journals.

Results: Between 17% and 33% of articles published in age-specific specialties are of high quality for clinical use. Top yielding journals for the specialties ranged from 16 to 130.

Conclusion: Handsearch of the clinical literature for the year 2000 reveals that high quality articles for some age-specific specialties are concentrated in a small subset of journals (eg, obstetrics), whereas articles for other specialties are widely scattered among a large number of journals (eg, adult medicine).


A real-time implementation of nonlinear control based on the technique of input-output linearisation is applied with the aid of a Texas Instruments C31 digital signal processor working at 16 MHz. Some results of simulation and practical results are presented. This article is limited to the results of regulation of the internal currents of the motor.


The EFM Award for Scholarship in Financial Research recognizes the researchers who, through their article published in the EUROPEAN FINANCIAL MANAGEMENT, have most contributed to our understanding of an important area of financial management. The winners of the EFM Top Download Award are selected by the number of downloads through Blackwell Synergy and other online hosts.


The effects of tuition costs, financial aid, and individual attributes on college choice are analyzed using a conditional logit model. The results confirm that financial aid can be an important determinant of postsecondary school attendance and that individual academic ability relative to the academic standards of a college is an important determinant of which of available college alternatives is chosen.


As the editors of Environmental Practice , we welcome all readers to this special issue on the National Environmental Policy Act (NEPA). NEPA has long been an interest of many environmental practitioners, perhaps especially those in the National Association of Environmental Professionals (NAEP), whose incorporation came five years after NEPA was signed into law on January 1, 1970.


Simple Summary According to consumer opinion, poor welfare leads to lower quality animal products. The stunning method plays a very important role as far as animal welfare, meat quality, and public health are concerned. The aim of the presented study was to assess the effect of two different stunning methods on the blood stress indicators and the quality of rabbit meat. The underlying goal was to improve the welfare of rabbits at the time of slaughter. The study was conducted on a commercial rabbit farm in Poland. The hybrids used in this study were obtained crossing Hyplus PS19 females with Hycole males (genotype I) and Jordan × Hycole females with Hyla males (genotype II). According to the presented findings, the genotype groups of rabbits differed in meat performance, but the differences in meat quality were minor. The examination of the blood stress biomarkers showed that both stunning methods are optimal when taking the welfare of rabbits into consideration. The presented research revealed some differences in the physiochemical traits of meat, with only slight differences between genotypes and stunning methods. Abstract The aim of the study was to assess the effect of two different stunning methods on the level of blood stress indicators (cortisol, insulin, glucose) and rabbit meat quality. The experiment was conducted on crossbreds of Hycole, Hyla, and Jordan rabbit strains: from mating Hyplus PS19 females with Hycole males (genotype I, n = 20) and Jordan × Hycole females with Hyla males (genotype II, n = 20). Prior to slaughter, the animals were weighed and divided into two groups according to the stunning method: 10 rabbits from each genetic group were stunned with an electric stunner, and the remaining 10 were stunned mechanically using a club. Genotype II was characterised by higher body weight at slaughter (p < 0.05), hot dressing percentage (p < 0.05), cold dressing percentage (p < 0.05), hot carcass weight (p < 0.05), and cold carcass weight (p < 0.05), compared to genotype I. The stunning method slightly influenced the meat lightness (p = 0.035). The meat of electrically stunned rabbits was characterised with higher drip loss (p < 0.0001) and lower plasticity (p = 0.043). Among the analysed traits of meat, only the drip loss (p = 0.014) and the percentage of extractable fat were affected by genotype (p = 0.044). Neither the stunning method nor the genotype affected rabbit meat texture characteristics. The study was undertaken because of the increasing importance of rabbit meat production as a developing sector of the meat industry and the need to improve the welfare of rabbits by selecting the most acceptable slaughter methods for these animals. To conclude, the analysed rabbit meat was characterised with good quality. There were only slight differences between genotypes and the stunning groups.


Thispaperconsiders oneaspectof theproblem ofthecontrol ofpowersystemsin theemergency stateexhibiting a severe viability crisischaracterized bylarge load/generation imbalances. Theproposed centralized control strategy resulsin structural action ondemand/generation andis basedonfastanddecentralized detection and estimation ofthepowerimbalance intheareas ofaninterconnected powersystem.Loworder dynamic observers areproposed toestimate the magnitude oftheimbalance usinglocally available measurements offrequency andtie-line powerflows.Guidelines forthedesignofthe proposed observer arepresented andillustrated onthepractically important example ofan interconnected powersystemmodel.


Suicide is now the third leading cause of death among adolescents and young adults. The rates of suicide among the 15-24 year olds in United States have increased from 2.7 per 100,000 in 1950 to 13.2 in 1990. In Israel the rates in this age group were 2.9 in 1955 with in increase to 5.0 in 1995. Suicidal behavior has been studied in United States, where 4 % of high school students had attempted suicide within the last 12 months and 8 % had attempted within their lifetime. A study from Israel found that 20 .6% of the girls and 13.5% of the boys had thought about attempting suicide, a suicide attempt had actually been planned by 8 -10%, 6 7 % had attempted and 3 4 % had made an attempt that required medical attention. It is therefore concluded that suicide is a serious problem in adolescence, which every health professional working with adolescents should be aware of.


Two cases of skeletal amyloidosis are described. In one the disease existed for many years, progressively destroying several vertebral bodies. There was no evidence of chronic infection, myelomatosis or cancer. In the other case myelomatosis was the primary disease but the first manifestation was a cystic tumour of the humerus. Not until several years later did typical bone lesions and Bence-Jones protein reveal the true nature of the disease.


In this study, two Carbon Molecular Sieves using Pistachio shell (CMS P) and Walnut shell (CMS W) were prepared by a chemical vapor deposition method and used for pressure swing adsorption and separation of CO/H2 and CO/CH4. Adsorption isotherms of gases obtained for both CMS's. The Dubinin-Radushkevich isotherm model was used for comparing pore volume of CMS's. The obtained isotherms for both CMS were compared with Langmuir and Freundlich isotherms. It was observed that Freundlich equation can better correlate the experimental data. The adsorption capacity of each CMS and selectivity of them for separation of CO/H2 and CO/CH4 were obtained with the aid of kinetic studies. In comparison with CMS W, CMS P showed higher adsorption capacity values for gases, but lower selectivity for separation of them. Finally by fitting experimental data to a pseudo second-order equation, adsorption capacities at equilibrium were obtained for abovementioned gases on both CMS's.


The most fundamental security goals include authentication and confidentiality both of which can be achieved by an authenticated key establishment (so-called AKE) protocol where the involving parties authenticate each other and generate cryptographically-secure (but temporal) session keys for their subsequent secure channels. As AKE protocols for wireless security, the IEEE 802.1x standard committee employed the Extensible Authentication Protocol (EAP) methods: EAP-MD5, LEAP, EAP-SIM, EAP-AKA, EAP-TLS, EAP-TTLS and PEAP. In this paper, we first revisit the EAP methods considering the following practical situation: (1) a user, who communicates with many different servers, remembers only one password and has insecure mobile devices (e.g., mobile phones or PDAs) with very-restricted computing power and built- in memory capacity; (2) the counterpart servers have enormous computing power, but they are not perfectly secure against various attacks (e.g., virus or hacker); (3) neither PKI (Public Key Infrastructures) nor TRM (Tamper-Resistant Modules) is available. For the above situation, we introduce an RSA-based AKE (for short, RSA-AKE) protocol that satisfies both higher level of security and efficiency over their kinds.


It is controversial that the Civil Procedure Act of the PRC and the Judicial Interpretation define representative action in Article 54 of the Act as joint action.If so,no class action would exist in China for representative action in Article 55 is in "dormancy." It clearly contradicts with reality and the statistical figure that shows that each year courts will handle several hundred thousand class action cases.Judging from their origins,similar foreign systems that they refer to and the characteristics and functions of their own,this author is sure that the two kinds of representative litigation in China's civil procedure law have gone beyond joint action and should be deemed to be by nature a third lawsuit-——class action rather than several action or joint action.


It is of utmost importance to optimise and stabilise hydrogen storage capacity during multiple cycles of hydrogen release and uptake to realise a hydrogen-based energy system. Here, the direct solvent-based synthesis of magnesium hydride, MgH2, from dibutyl magnesium, MgBu2, in four different carbon aerogels with different porosities, i.e., pore sizes, 15 < Davg < 26 nm, surface area 800 < SBET < 2100 m2/g, and total pore volume, 1.3 < Vtot < 2.5 cm3/g, is investigated. Three independent infiltrations of MgBu2, each with three individual hydrogenations, are conducted for each scaffold. The volumetric and gravimetric loading of MgH2 is in the range 17 to 20 vol % and 24 to 40 wt %, which is only slightly larger as compared to the first infiltration assigned to the large difference in molar volume of MgH2 and MgBu2. Despite the rigorous infiltration and sample preparation techniques, particular issues are highlighted relating to the presence of unwanted gaseous by-products, Mg/MgH2 containment within the scaffold, and the purity of the carbon aerogel scaffold. The results presented provide a research path for future researchers to improve the nanoconfinement process for hydrogen storage applications.


Low-subsonic tests on 2 full-span high-lift configurations in the NLR-HST and 0NERA-F1 facilities have been compared. A short experiment in an HST closedwall test section has been added. HST slotted-wall and F1 closed-wall results agree very well. HST results do not suffer from measurable wall-interference effects. Some differences, however, are observed between HST slotted-wall and solid-wall test results, the latter corrected for wall interference in the classical AGARDograph 109 manner. This discrepancy - found notably at higher CL 's - may well be attributable to a deficient wallinterference correction.


Modeling and rendering of atmospheric phenomena such as clouds is one of most difficult research themes in the field of computer graphics, mainly due to its complexity, huge volume, ubiquitousness, etc. In this paper, we represent a system for real-time modeling and rendering of clouds, mainly aiming at the computer games and flight simulation applications. Our implementation generates various kinds of clouds including cirrus, stratus, and cumulus, through intuitive real-timeuser interactions. Then, additional details are automatically attached to them, using our own methods based on meta-balls or hierarchical spherical particles. After processing multiple scattering and anisotropic scattering, resulting particles are rendered into billboards, to finally achieve real-time processing.


Objective To assess clinic value of esophageal stent placement in the benign and malignant esophageal strictures,and the influence of stents selection on curative effect. Method 36 cases of esophageal strictures, 5 cases of benign strictures,31cases of malignant strictures,including 4 cases with esophagotracheal fistula and 3 cases with esophagomediastrinal fistula. 26 domestic Nickel-Titanium alloy memorial netlike stents and 14 membrane-covered stents were used for the treatment. All patients were treated by placing esophageal stent perorally under fluoroscopic guidance. Results 40 stents were planced successfully in 36 cases, only one case showed membrane covered stent migrating. Symptoms of dysphagia were considerably relieved after stent insertion. The total effective rate was 97.2%. Conclusion The esophageal stent is an effective and safe treatment for benign and malignant esophageal stenosis: The nutritive condition and the quality of life of patients are improved, which is favourable for tumor further treatment. Appropriate stent selection can keep esophageal patent rate and decrease sliding rate.


The latest offshore wind turbines are easily exposed to lightning strikes because they are designed with longer blades and taller height to satisfy the growing capacity demands. The generation facilities and elements of the offshore wind farm are more vulnerable to lightning damage because of more severe, unpredictable weather conditions. Therefore, this paper presents the analysis of measure for lightning overvoltage mitigation in offshore wind farm planned in South Korea southwest seashore. The sensitivity analysis includes the steady state and transient state characteristics of offshore wind farm and proposes the countermeasure for mitigation of transient overvoltage by considering earth resistivity of the offshore environment.


The present experiment was conducted during the year 2016-17 at Regional Horticulture Research Station, Navsari Agricultural University, Navsari. The experimental results indicated that media (M3) red soil + FYM + vermicompost (1:1:1) noted greater germination percentage (82.11%), height of seedling at 120, 150 and 180 DAS (29.38 cm, 38.53 cm and 47.00 cm, respectively), number of leaves (22.48, 30.29 and 36.34, respectively) and stem diameter (2.10 mm, 2.70 mm and 3.12 mm, respectively). Whereas, the maximum fresh (17.67 g) and dry weight (10.06 g) of seedling, vigour index- I (3859.66) and II (826.02), highest survival percentage (75.26%) and least mortality percentage (24.73%) was noted in (M3) red soil + FYM + vermicompost (1:1:1) at 180 DAS. Among the foliar spray treatment, (F4) panchagavya @ 3% was significantly improved growth parameter viz., height of seedling at 120, 150 and 180 DAS (29.64 cm, 38.30 cm and 47.32 cm, respectively), number of leaves (22.22, 30.69 and 36.31, respectively) and stem diameter (2.10 mm, 2.73 mm and 3.12 mm, respectively). Likewise the highest fresh (17.97 g) and dry weight (10.02 g) of seedling, vigour index- I (3681.89) and II (778.31), highest survival percentage (75.20%) and least mortality percentage (24.82%) was noted in same foliar spray at 180 DAS. The interaction effect between the media and foliar spray had a significant effect only on height of seedling at 150 and 180 DAS as well as number of leaves at 150 DAS. The maximum height of seedling (42.87 cm) at 150 DAS and 51.90 cm at 180 DAS as well as the highest number of leaves (35.07) at 150 DAS was recorded in treatment (M3F4) red soil + FYM + vermicompost (1:1:1) and Panchagavya @ 3%.


PURPOSE: To improve the quality of a color print by controlling the discontinuity of the entire color area and a blur nearby a color border. CONSTITUTION: A color print tends to have a blur of incompatible ink like real black ink and color ink across a color field border. A four-color system has discontinuity of the entire physical color area in relation with excessive colors distinctively from the entire logical color area. This method adjusts image data before dithering to solve those problems. Logical colors displayed in the image data are slightly shifted to evade discontinuity appearing together with intermediate colors. The four-color system preferably reduces yellow of the image data and prints more dots of blue ink in a specific area. For each pixel, a correction quantity is in inverse proportion to color saturation. The presence of the blue ink dots in a substantially black field reduces the spread nearby the field border edge.


We assess the importance education as a signal of workers skills and the e¤ects of poor signaling quality on labor market outcomes. We do so by merging a frictional labor market model with a signaling setup where there is a privately observed idiosyncratic component in the cost of education. Given that highly skilled workers cannot correctly signal their abilities, their wages will be lower and they will not be matched to the "right" vacancies, or may be unemployed. Skilled workers will then have lower incentives to move to high productivity markets. Furthermore, fewer vacancies will be created in labor markets where skills matter, and incentives for workers to invest in education will be lower. Overall, an economy where education is a noisier signal generates lower educational attainment, higher unemployment and lower productivity. In addition, we provide evidence suggesting that education plays a poor signaling role in Latin American countries. We then calibrate our model using Peruvian data, and through a quantitative exercise we show that this mechanism could be relevant to explain the relatively bad performance of labor markets in Latin American countries.


Rising worldwide adolescent smoking necessitates national and global research to establish intervention methods. This research evaluated the efficacies of ask, advise, assess, assist, arrange (5A's) and ask, advise, act (3A's) interventions. Self-reported quit-smoking attempts were the outcome measure. Six villages were randomly selected and equally divided into three groups: 5A's, 3A's, and control (no intervention). There were 519 current participant-smokers aged 13-17 followed-up by phone (first and third months) and face-to-face interviews (sixth and ninth months). Most 3A's participants (n=12, 7.1%) quitted smoking in the first month, followed by the 5A's (n=9, 5.3%) and the control (n=3, 1.9%). In the third month, 5A's participants topped the rank (n=16, 10.7%), followed by the 3A's (n=14, 9.2%), and control (n=5, 3.4%). As per sixth-month follow-up, the 5A's group maintained its position on top of the list (n =27, 21.4%), followed by the 3A's (n=22, 17.1%) and the control (n=5, 4.0%). The majority of 5A's participants quitted smoking after nine months (n=36, 33.0%), followed by the 3A's (n=27, 25.5%), while control maintained its position (n=5, 5.0%). Division health officers and school health-teams nationwide should implement them.


Neoliberalism is the political‐economic system that has characterized the United States for the past half century. Structurally, neoliberalism has involved privatization, deregulation, and government divestment from public health systems. Cultural psychologists have begun to outline the ways that neoliberalism is reflected in attitudes, ways of being, and ideologies, such as in the form of heightened individualism, justification of inequality, depoliticization, and precarity. We argue that neoliberal structures and psychologies may contribute to deleterious outcomes in the context of the COVID‐19 pandemic. We demonstrate that neoliberalism at the US state level (n = 51) is associated with higher COVID mortality and case fatality rates, as well as lower vaccination rates (Study 1). We also demonstrate that individual‐level (n = 8280) neoliberal ideology predicts less adaptive beliefs and attitudes such as the belief that the federal response to the pandemic was too fast and belief in COVID‐related misinformation (Study 2). We demonstrate using multilevel modeling that state‐level neoliberalism predicts individual‐level COVID‐related attitudes, which is explained in part by heightened neoliberal ideology in more neoliberal states (Study 2). This study contributes to an understanding of the structural and cultural psychological factors that have contributed to the severity of the COVID‐19 pandemic in the US.


This study was created based on concerning the importance of efficient language use. The language use can be called efficient if the message is unambiguous, clear, and can be understood by both speaker and listener. This study purposes to investigate the violation of quality maxim, quantity maxim, relevance maxim and manner maxim of Grice Maurice maxim's Cooperative Principle in the conversation of characters in Beauty and the Beast movie. In fact, there are several maxim violations that happened in human life especially figured in the movie. The maxim violation may cause misunderstanding while the conversation is going on. Descriptive qualitative method was used in this research, the data are collected from the conversation in the movie which contains coversational implicature in the character's utterance. The result of the research shows that there is four type of maxims that are violated by Maurice's coversation in Beauty and the Beast movie. The four type of it such as maxim of quality, maxim of quantity, maxim of relevance and maxim of manner. The result of the research shows that the maxim of quality is dominant, because the character give lacks evident, maxim quantity, maxim of relation, and maxim of manner are also violated in this movie. Keywords:  Cooperative Principles, Movie, Violation


Setting an optimal inspection plan for fatigue critical offshore piping relies on accurately estimating its remnant fatigue life (RFL). Several modeling approaches, such as knowledge-based, model-based, data-driven, fusion techniques etc., have been used to build RFL models in the past. The aim of this paper is to review these approaches and thereby recommend the most favorable approach for building a probabilistic RFL model for offshore piping. Firstly, a brief discussion about the aforementioned approaches is presented. Thereafter, a comparison is made between these approaches. For instance, there is uncertainty in model-based approaches, due to the assumptions of the underlying physical model, which poses substantial limitations on this approach. Conversely, a data-driven approach exploits the monitored operational data associated with the condition of the piping system. Fusion technique combines the features of the former two approaches and is recommended to build a model for estimating the RFL of offshore piping.


Thermoelectric generation is a promising technology which converts waste heat into electricity in an efficient and clean way. Thermoelectric application could utilize the heat from a device to power a thermoelectric generator (TEG) which in turn produces power that could run a cooling system. Such systems would be critical in transportation, remote area or other applications where system reliability is of a paramount importance. Thus, in this paper a detailed parametrical analysis and optimization of the geometrical and system parameters are made so as to provide guidelines for the design of self-cooling devices. A simple and accurate 2D numerical model is developed which facilitates a quick analysis of design variables. Numerical data is within a good agreement (within 6%) with existing experimental data. The effect of extender height (Hext), fin base height (Hfbase), number of fins (Nfin) ranging from 10 mm to 50 mm, 2 mm to 12 mm, 24 to 64 respectively has been studied. In addition, the feasibility of using double and triple cascaded TEG system is investigated. An optimization algorithm to optimize system paramaters is implemented. Nomenclature h = convection heat transfer coefficient (W/m 2 .K) Tg = temperature inside the device H = height(mm) Th = temperature at hot side of TEG I = electric current (A) Ts = temperature at cold side of TEG = current density (A/m 2 ) Tamb = ambient temperature k = thermal conductivity (W/m.K) v = velocity of air in fan (m/s) l = length (mm) w = width (mm) n = n-type semiconductor elements x,y = Cartesian coordinates Nfin = number of fins p = p-type semiconductor elements P = electric power (W) g Q  = heat generation rate (W) R = thermal resistance (K/W) Rel = electric resistance of the thermoelectric module (Ω) Rld = electric load resistance connected to the module (Ω) Rth = thermal resistance of the thermoelectric module (K/W) T = temperature (°C) t = time (s) Greek Symbols  = seebeck coefficient (V/K) ρ = electrical resistivity (Ωm) ΔT = temperature difference 1 PhD Student, Department of Mechanical and Materials Engineering, Miami, Florida. AIAA student member. 2 Associate Professor, Department of Mechanical and Materials Engineering, Miami, Florida. AIAA member. 3 Visiting PhD Researcher, Department of Mechanical and Materials Engineering, Miami, Florida.


11066 Background: STUMP ecompass a group of uterine mesenchymal neoplasms in which the clinical behavior cannot be predicted on morphological grounds. A malignant clinical evolution is seen in approximately 10-20% of cases. When STUMP relapse, the label of "low-grade leiomyosarcoma" is sometimes found to be appropriate, though current histopathological criteria for uterine leiomyosarcoma (so called "Stanford criteria") would exclude even the existence of low-grade uterine smooth muscle neoplasms. As they express ER and PR, hormonal treatment with GnRH inhibitors or aromatase inhibitors (AIs) may represent a therapeutic option. Methods: From October 2015, we have been treating with hormonal therapy relapsing patients with an initial diagnosis of STUMP, whose pathological aspect on retrospect was consistent with a "low-grade uterine leiomyosarcoma". We identified 8 patients. Pathological diagnosis was centrally reviewed by expert sarcoma pathologists. Results: Eight pts were treated: 7 in first line; 1 pt in 4th line, following failure of chemotherapy (gemcitabine and taxotere, adriamycin and dacarbazine, trabectedin). Two premenopauseal pts were treated with GnRH inhibitors, 2 with a combination of GnRh inhibitors and an aromatase inhibitor, 3 with aromatase inhibitors only and 1 with selective progesterone-receptor modulator. 7 patients are evaluable for response and all of them had a partial response as best response. Median progression-free survival was 31 months. Conclusions: In our series, all patients with a centrally reviewed diagnosis retrospectively consistent with a "low grade uterine leiomyosarcoma" responded to hormonal treatment. Therefore, these pts may make up a subgroup with therapeutic and prognostic relevance. "Stanford criteria" need to be re-assessed, in an effort to improve prognostic and therapeutic stratification of uterine smooth muscle neoplasms, possibly shrinking the scope of currently defined STUMP.


A 56-year-old man presented with multiple redviolaceous firm, nontender nodules and plaques on the left frontal and parietal areas of his scalp (Figure 1). There was no regional lymphadenopathy. The patient denied any fever or chills. His medical history was significant for diabetes mellitus and hypertension, for which he was taking metformin, troglitazone, glyburide, and enalapril maleate. There was no personal or family history of cancer. A skin biopsy specimen from a scalp lesion showed a dense atypical lymphocytic infiltrate suggestive of malignant lymphoma (Figure 2). Results of extensive investigation including a bone marrow biopsy, lymph node biopsy, and computed tomographic scan of the chest, abdomen, and pelvis were negative for systemic lymphoma. A specimen from a repeated biopsy was submitted for flow cytometric analysis and Southern blotting for Band T-cell receptor rearrangement. Immunophenotypic analysis showed a mixture of B and T cells. The T cells showed expression of CD3, CD5, and CD7 with markedly reduced and almost absent CD2, while the B cells expressed CD19, CD20, and CD22 with no evidence of surface immunoglobulin light chain restriction (Figure 3). This was suggestive of an atypical T-cell population. There was no Tor B-cell rearrangement on the first Southern blotting examination of the specimen; however, another examination of the specimen, which was submitted for Tand B-cell gene rearrangement analysis with restriction enzymes, demonstrated the presence of a monoclonal B-lymphocyte population indicative of a follicle center B-cell lymphoma. The patient did not want to undergo surgery, radiotherapy, or systemic chemotherapy.


Abstract Sematophyllum substrumulosum (Hampe) Broth. was found in 1995 on a decaying trunk of Pinus in Tresco, Isles of Scilly, the first report of the species in the British Isles.


Forward–backward multiplicity correlations have been measured with the STAR detector for Au + Au, Cu + Cu and p + p collisions at . A strong, long-range correlation is observed for central heavy-ion collisions that vanishes in semi-peripheral events and p + p collisions. Both the dual parton model and the color glass condensate indicate that long-range correlations are due to multiple parton interactions. This suggests that dense partonic matter might have been created in mid-central and central Au + Au collisions at .


in the x direction need to be considered, Le., the problems are one dimensional. The collector-base junction depletion region ends at the plane n: = wa, the outer surface of the emitt'er region is at the plane x = -we, and Ohle emitterbase junction at z = 0. (This neglects the width of the emitter-base junction depleton region. The region is ordinarily so thin that this is a good approximation; and if desired, the positions of the edges of this region can easily be subst'ituted for zero in the limits of the definite integrals in terms of which the result will be obtained.) For definiteness, a p-n-p transistor is assumed; the results, of course, can be applied just as well to other cases. The desired quantities are then


This paper describes the impacts on transit that were observed in the evaluation of the Urban Partnership Agreement in Seattle, Washington. In December 2011, variable tolls were instituted on the SR-520 bridge in Seattle. Transit service frequency was enhanced approximately 11 months before tolling. The Seattle findings compared favorably with other congestion pricing projects across the United States and the world. Ridership across the SR-520 bridge increased 10% after the new service was added. It increased another 14% after tolling. The larger increase that came after tolls was similar to that observed in Stockholm, Sweden, and Minneapolis, Minnesota. Speeds across the bridge increased by 14 to 18 mph. That increase was higher than the increase observed in London but lower than the increase observed in Miami, Florida, and in Minneapolis. In the pretoll survey of SR-520 bus riders, 19% said they were influenced to take transit by the enhanced transit service. An even greater percentage, 55%, said the tolls influenced them to take transit. In Atlanta, Georgia, Miami, and Minneapolis, the percentage of riders influenced by the tolls was 45%, 53%, and 23%, respectively. In the posttoll survey, 57% of riders said the tolls on SR-520 had improved their personal travel. Altogether, these findings reconfirm that congestion pricing can create a tangible incentive to take transit.


Abstract In this paper, the ideological and political education path is designed according to the spirit of Yan'an. In order to verify the feasibility of the path, as well as to make the student evaluation more effective and objective, the article combines the K-means algorithm and proposes a K-means algorithm based on neighborhood spatial density optimization (NDK-means). The algorithm assists in solving the problem of grading the reliability of student assessment and realizes the labeling of student assessment reliability data. Then, based on the student assessment reliability characteristics and data labeling results, a BP neural network prediction algorithm (CSA-BP) based on crow search improvement is proposed to model the student assessment reliability. The results show that the percentages of freshmen to seniors who are satisfied with the Civic Education proposed in this paper are 85.9%, 82.26%, 76.75%, and 72.45%, respectively, in terms of grade level. Students from urban, rural, and rural areas, in terms of their place of origin, all feel satisfied with the current teaching of Civics and Political Science at 80% or more.


Objective:To study the treatment effects of different styles of gastric bypass surgery on type 2 diabetic GK rats.Methods: Thirty male GK rats from six-week-age to eight-week-age were randomly divided into five groups,group 1 was operated by Roux-en-Y gastrojejunostomy with duodenum exclusion and stomach capacity maintenance,group 2 was operated by loop-type gastrojejunostomy with duodenum exclusion and stomach capacity maintenance,group 3 was operated by Roux-en-Y gastrojejunostomy with partial gastrectomy,group 4 was operated by loop-type gastrojejunostomy with partial gastrectomy.The length from jejunal anastomotic stoma to the ligament of Treitz in group 1 and 3 and the length from gastrojejunal anastomotic stoma to the ligament of Treitz in group 2 and 4 was 3cm,group 5 was operated as the same way as group 1,but the length from jejunal anastomotic stoma to the ligament of Treitz was 10cm.The changes of FBG and OGTT in different groups were observed and recofede.Results: Every had good effect on controlling blood-glucose,there were no patent differences between group 1 and 3(P0.05),as well as between group 2 and 4(P0.05),but group 1,3 and 5 were more effective than those in group 2 and 4(P0.05).The OGTT peak value at 36-week postoperation reduced in group 1 and 5(P0.05),but not in group 2,3 and 4(P0.05).The OGTT 3 h level at 36-week postoperation had obvious improvement in group 1,3 and 5(P0.05),but not in group 2 and 4(P0.05).There were also no patent difference in the OGTT peak value and the OGTT 3h level at 36-week postoperation between them(P0.05).Conclusions: Gastric bypass surgery is effective to treat type 2 diabetes mellitus(T2DM),the Roux-en-Y gastrojejunostomy with duodenum exclusion and stomach capacity maintenance is a relatively perfect operative style for not only controlling blood-glucose most effectively but also decreasing adverse effect of the body to the minimal level.Further more,we should not increase the length of intestinal loop that excluded blindly.


Purpose: The purpose of this study is to identify factors influencing burnout in primary family caregivers of Home Health Care Patients. Methods: Data were collected from 121 primary family caregivers of home health care patients in three different hospitals in 'D' metropolitan city and the study was conducted from August 10, 2016 to January 17, 2017. The data were analyzed using descriptive statistics, t-test, ANOVA, Pearson's Correlation Coefficient, Stepwise Multiple Linear Regression. Results: Mean scores for the nursing needs of the participants were 3.54±0.79, the family functions were 1.24±0.58, the burnouts were 2.74±0.49. The burnouts were positively correlated with the nursing needs but inversely correlated with the family function. The factor that had the greatest influence on the burnouts of primary family caregivers of Home Health Care was family function (β=-.245, p=.001), followed by patients'' daily activity (β=-.213, p=.014), age (β=.208, p=.032), monthly nursing services cost (β=-.196, p=.044) and nursing needs (β=.129, p=.014). The Explanatory Power of Models was 23%. Conclusion: Individually customized home care nursing intervention programs are required to be provided in accordance with patient''s family function and daily activity, monthly home care nursing service cost, nursing needs and general characteristics of primary caregivers of Home Health Care Patients such as their age, the number of family members living together, sex and the name of disease.


This paper outlines supply chain management (SCM) together with problems existing in the application of SCM. Then the paper describes a new kind of Web Service technology and its service - oriented architecture . Also the paper thoroughly analyzes the promotion of the supply chain management system by Web Service technology. In the end, the trend of the application of Web Service to SCM products are demonstrated.


BonJourl offers two main reasons for supposing that there is such a thing as rational insight into necessity. First, he says there are many examples in which it clearly seems that one has such insight. Second, he argues that any epistemology denying the existence of rational insight into necessity is committed to a narrow skepticism. After commenting about possible frameworks for epistemological justification, I argue against these two claims in reverse order.


Objective To study the prevention and treatment of dysuria after Transurethral electroresection of prostate.Methods From January 1966 to October 2004,24 cases with dysuria or urinary retention after transurethral electroresection of prostate and after removing urinary catheter were analyzed retrospectively and it's managed measures were summarized.Results The main cause of dysuria were edema of prostate urethral stricture,residual tissues,clot(blood)and obstruction of calculi etc. It was settled by prolonged time of keeping urinary catheter,dilating urethra,removing obstuctive contents. Conclusion Preoperative enough prepartion and careful managment in the tip of prostate which can reduce the postoperative dysuria.If the effective measures are taken after operation in time,the dysuria can be settled.


We have newly synthesized a class of photochemical 1,8-naphthalimide dyes. Photochemical investigation strongly suggests that these dyes function as photoalkylation agents following activation to an intermediate state by visible light (circa 420 nm) excitation. The activated species reacts readily with nucleophilic amino acid residues, e.g., tryptophan, cysteine, and methionine. One dye, 1,14-bis-(N-hexyl-3'-bromo-1,8'-naphthalimid-4'-yl)-1,4,11,14- tetraazatetradecane-5,10-dione, which incorporates two reactive 1,8-naphthalimide groups at each end of an intervening structural bridge has been used to cross-link the protein monomers of F-actin, thus preventing its natural depolymerization at low salt concentrations, and to cross-link Apolipoprotein I of human high-density lipoprotein. These observations suggest continued study of these dyes as agents for protein cross-linking, tissue bonding, and inactivation of infectious agents.


Background: Direct psychiatric consultation is not still prevalent in India, even in health care professionals due to stigma regarding mental illness. This delay in referral and failing to identify psychiatric symptoms in the right time is responsible for undue morbidity. Hence studies regarding cross referrals and liaison psychiatry is the need of the hour in providing comprehensive health care to the patients. It is really welcoming sign that mental health services had moved from mental hospital to a general hospital setting which made the availability of psychiatric services closer to the public and made an effort to reduce the prevailing stigma Materials and Methods: Referrals to Psychiatric Department were assessed for six months period with 505 patients. Out of these, 384 were inpatients referred from the general hospital and other hospitals, 59 were outpatients referred from various specialities, and 62 were from the emergency unit. Results:. Only one-fifth of cases diagnosed of which around 50% given diagnosed appropriately by clinicians. Single-visit and opinion was the most common mode of disposal Conclusion: Impulsive Suicidal attempt and Deliberate self harm are the most common reason for referral. Mood disorders are a common psychiatric illness observed in individuals attending medical emergencies. -------------------------------------------------------------------------------------------------------------------------------------Date of Submission: 07-08-2019 Date of Acceptance: 29-08-2019 -------------------------------------------------------------------------------------------------------------------------------------


In order to achieve a good correlation between toxicology and Artemia salina lethality test, several chemical pollutants were examined in A. salina test, with the purpose to use the latter as convenient preliminary protocol for toxic activity. During the test, it was observed the effect of a particular lethal dose or only a knockdown in the arthropod of HgCl2, KCN, K2Cr2O7, C6H6 and C6H6Cl6. The 24h LC50 of these five chemical pollutants to the artemia nauplius was 0.12±0.09, 0.06±0.12, 0.72±0.21, 1.57±0.58 and 0.44±0.10 mg/L, respectively. The results of the A. salina lethality test for the chemical substances are essentially in agreement with those described in literature for toxic activity.


The precise etiology for idiopathic Parkinson's disease (PD) is currently unknown; however several lines of converging evidence exist to suggest a central role of pathlogic aggregation of alpha-synuclein as a driving force underlying mechanisms of PD neurodegeneration. First, pathogenic missense mutations1 or gene multiplications2 of the alpha-synuclein gene (SCNA) result in an increased propensity for alpha-suniclein to fibrillize in vitro3 and clinically manefest as early-onset PD with typical Lewy pathology (LP) composed chiefly of insoluble amyloid fibrils formed by pathologically altered alpha-syunclein proteins at autopsy.4 Comparisons of large numbers of PD cases at autopsy demonstrate a sequential non-random progression of LP from the lower brainstem into limbic and neocortical regions in the majority of PD patients.5 This progression of LP into neocortical areas appears to be the strongest neuropathological correlate of dementia in PD,6–8 further reinforcing the importance of alpha-synuclein misfolding and aggregation into LP in the neurodegenerative process. Finally, recent work in cell9, 10 and animal11, 12 models of PD demonstrated that pathological alpha-synuclein proteins may spread from neuron-to-neuron to induce LP as well as neurodegeneration. Furthermore, in animal models, this process recapitulates clinical and pathological phenotypes of PD, thereby mirroring the proposed staging systems5, 13 of LP in human disease. Indeed, alpha-synuclein fibrils alone, appear to be capable of transmission of LP within an animal.11, 12 Despite these similarities to PrPsc neuron-to-neuron transmission in the spongiform encephalopathies,14 there is currently no data to suggest humans15 or non-human-primates16 exposed to pathogenic alpha-synuclein from brain tissue of PD patients develop clinical PD. Thus, the apparent lack of transmission between individuals is in sharp contrast to human prion disease.


ABSTRACT: Italians residing in Piedmont (Northwest Italy) KEYWORDS: forensic science, DNA typing, population genetics, Piedmont, Italians, D3S1358, TH01, D21S11, D18S51, Penta E, D5S818,D13S317, D7S820, D16S539, CSF1PO, Penta D, vWA, D8S1179, TPOX, FGA Several studies on allelic frequencies of tetrameric STR loci(CODIS loci) in the Italian population have been published; how-ever, data regarding the distribution of recently introduced pen-tameric loci are still scarce.Blood/saliva samples were obtained from 147 unrelated Ital-ians residing in Piedmont (North West Italy). Genomic DNAwasisolated by means of spin columns (Macherey-Nagel, D¨uren,Germany).PCRamplificationwasperformedaccordingtotheman-ufacturer's instruction using the GenePrint TM R PowerPlex 16 Sys-tem (Promega Corporation, Madison, WI). The amplified productswere detected with the 310 Genetic Analyzer (Applied Biosys-tems, Foster City, CA). Hardy-Weinberg equilibrium was evalu-ated by exact test using the software GENEPOP Version 3.3 (1).


Citations for some characters in A Comprehensive Dictionary of Chinese Characters are not the earliest written examples of their usage,which may affect readers' search for characters' semantic development.In this paper,a few earlier cases for certain words are added for readers' reference.


Experiences of Parenting for African American Female Survivors of Childhood Sexual Abuse by Chelsea Sharpe MS, Troy University, 2007 MEd, Troy State University, 2004 BS, Georgia Southern University, 1999 Dissertation Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy Counselor Education and Supervision Walden University May 2018 Abstract Childhood sexual abuse (CSA) has been linked to a number of adverse effects in adulthood including higher levels of depression, shame, guilt, self-blame, somatic concerns, anxiety, dissociation, repression, denial, relationship problems, and sexual problems. Little is known, however, about the influence CSA has on parenting, specifically among African American mothers, as previous researchers have primarily focused on the trauma experienced by survivors. Examining the impact of CSA on African American mothers' parenting is important as those children of survivors will often also experience the impact of the long-term sequelae associated with CSA. Guided by womanist theory, the purpose of this hermeneutic phenomenological qualitativeChildhood sexual abuse (CSA) has been linked to a number of adverse effects in adulthood including higher levels of depression, shame, guilt, self-blame, somatic concerns, anxiety, dissociation, repression, denial, relationship problems, and sexual problems. Little is known, however, about the influence CSA has on parenting, specifically among African American mothers, as previous researchers have primarily focused on the trauma experienced by survivors. Examining the impact of CSA on African American mothers' parenting is important as those children of survivors will often also experience the impact of the long-term sequelae associated with CSA. Guided by womanist theory, the purpose of this hermeneutic phenomenological qualitative inquiry was to explore the lived experiences in relation to parenting of African American mothers who survived CSA. Experiential anecdotes of data collected from interviews with 7 participants were hand coded for emergent themes; analysis generated 4 essential themes and 10 subthemes of experience. Themes included impact of abuse, bonding, efforts to protect, spirituality, and desires. This study's implications for positive social change include contributing to the knowledge base about the process of parenting experienced by African American female survivors of CSA. Findings may add insight shedding light on cultural nuances in parenting and coping with trauma and inform culturally-competent practice. Using study findings, mental health providers may be able to develop tailored treatment interventions and better support services for the prevention of adverse long-term effects of CSA in African American women. Experiences of Parenting for African American Female Survivors of Childhood Sexual Abuse by Chelsea Sharpe MS, Troy University, 2007 MEd, Troy State University, 2004 BS, Georgia Southern University, 1999 Dissertation Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy Counselor Education and Supervision


Introduction This article gives an overview of Vehicular Ad Hoc Networks (VANETs), starting with a brief discussion of the larger Mobile Ad Hoc Network (MANET) concept followed by a description of VANETs and their characteristics. Its purpose is to provide an insight into potential military applications of VANET technology. MANETs and VANETs provide an exciting prospect for ad hoc military communications in areas with little or no usable infrastructure. For instance, in peacekeeping or responses to humanitarian disasters such as a major flood, their Commercial-Off-The-Shelf (COTS) technologies make them an attractive tool for first responders, be they military or civilian. Background The traditional distributed system was first introduced approximately 20 years ago using fixed infrastructure [1]. Since then nomadic distributed systems have gone on to combine wireless edges with a fixed core infrastructure, where the load is primarily carried on the fixed infrastructure [1]. In this regime, the periphery of the communications system is composed of wireless devices potentially using a combination of Bluetooth, 802.11/WiFi, and similar technologies; these in turn connect to a fixed central infrastructure, composed predominantly of dedicated physical wire links of various types, potentially with a small proportion of point-to-point wireless technologies (e.g. microwave).


Preface
Introduction: Problems and a hypothesis
Chapter I : Pre-Dignaga theories of inference and logic in various schools of Indian philosophy
 1. The Carakasamhita
 2. The Vaisesika school
 3. The Samkhya school
 4. The Nyaya school
 5. The Mimamsa school and others
 6. A summary
Chapter II : Pre-Dignaga Buddhist theories of inference and logic
 1. The *Upayahrdaya or *Prayogasara
 2. The Sandhinirmocanasutra
 3. The Yogacarabhumi
 4. Asanga
 5. The *Tarkasastra
 6. Vasubandhu
Chapter III : Dignaga
Chapter IV : Post-Dignaga logicians of non-Buddhist schools
 1. Prasastapada of the Vaisesika school
 2. Uddyotakara of the Nyaya school
 3. Kumarila Bhatta of the Mimamsa school
Chapter V : Dharmakirti
Conclusion
Notes & Bibliography


Alloying Pt with highly oxophilic transition metals such as Rh, Ni, or Sn has been a promising strategy to modify the electrocatalytic surface properties of Pt in order to supply active oxygen-containing species for ethanol electrooxidation. A new, highly active, ternary single-phased fcc PtRhNi/C nanoparticle electrocatalyst for the electrocatalytic oxidation of ethanol (EOR) is reported and its morphology (XRD and TEM), composition (inductively coupled plasma optical emission spectroscopy), and electrochemical activity are discussed in comparison with the state-of-art PtRhSn/C electrocatalyst. The EOR activity of the PtRhNi/C material outperformed the benchmark PtRhSn/C material in acidic and alkaline media, showing high stability, especially in alkaline media. The higher intrinsic EOR activity of the Ni-containing electrocatalyst lends support to the notion that surface NiOx is an excellent oxygenate-supplying catalyst component for the oxidation of ethanol.


The change of resistivity during isothermal aging after quenching were measured in Al–10wt%Zn–0.13wt% Mg and Al–10wt%Zn–0.3wt%Mg alloys. General features of clustering in these alloys were different from those in binary Al–10wt%Zn alloy. Small increase of resistivity occured before main increase of resistivity due to clustering of Zn atoms. This small increase of resistivity was attributed to clustering of both Mg and Zn atoms into G. P. zones which were diffrent from those in binary Al–Zn alloys. Time required to reach maximum of resistivity in these aloys was much longer than those in binary alloys. it was deduced that this fact did not depend upon large binding energy between an Mg atom and a vacancy but might be due to interaction between G. P. zones containing both Mg and Zn atoms and vacancies.


In the article the possibilities of use of non-traditional means and techniques during teaching and up-bringing the children with sensory abnormalities are reviewed. The directions of correction influence, which contribute to the development of mental processes of children with abnormalities of hearing and eyesight are discussed.


To provide design reference to fin projectile fuze,the process of projectile impacting vulnerable targets of different material and thickness with diferrent inpact angle was numerically simulated by ANSYS/LS-DYNA.The simulation results indicated that the set-forward overload factor of projectile impacting vulnerable target reached the top value with a certain impact angle,which varying with diferrent material and thickness of the targets.When super caliber fin-stabilized projectile impacted target board by large impact angles,the biggest set-forward overload factor occured while the fin penetrating target board but not projectile head penetrating the board.The test results proved that the fuze inertia contact switch designed based on the simulation data could satisfy the demandes on insensitivity,ballistic safety and graze burst action efficiency.


The invention discloses a POE load detecting method and power supply terminal equipment. The method comprises the steps that the power supply terminal equipment PSE outputs a first specified voltage value at the output end of a POE control circuit, equivalent additional resistance is detected when no load exists between the POE power supply wire pair; a second specified voltage value is outputtedat the output end of the POE control circuit, first resistance between the POE power supply wire pair is obtained via detection so as to take the first resistance as the parallel equivalent resistance of the equivalent additional resistance and the load resistance; the resistance value of the load resistance is obtained according to the detected first resistance and the equivalent additional resistance so as to determine whether the load resistance value meets preset judging conditions, and the externally connected receiving end equipment PD is determined to be effective if the judging conditions are met. The method and the equipment provided by the invention can detect the equivalent additional resistance, thereby reducing the erroneous judgment on the effectiveness of the externally connected PD.


This paper examines the trends in publication and citation of Galemys, the scientific journal of the Spanish Society of Mammalogist (SECEM) in the last 15 years. We reviewed the citations obtained in the 38 issues of Galemys published between 1997 and 2012 in journals covered by the Journal Citation Reports, as well as in the journal itself. As a whole, 425 articles have been published in Galemys (296 articles and 129 short notes), with an average of 26.5 ± 13.2 (SD) items / year. There have been 596 citations to 408 articles and notes published in Galemys, both in international journals (349 citations, 58.6%) and in the journal itself (247 citations, 41.4%). The average impact of Galemys in the period 1997-2012 was 0.09 citations/year, with a five-years impact factor of 0.15 citations/year, and with a halflife of 7.5 years. Galemys is currently only moderately used by the scientific community, but patterns of use are growing, especially by the Spanish mammalogists linked to the SECEM. Its potential for future use and larger impacts is probably high. This suggestion is sustained on results obtained on recent trends, together with the expected effect of the lasts changes in the journal, especially its open access publication an identification with a DOI and their inclusion in the CrossRef database.


This study examines the political implication of "Directive Principles of Fundamental State Policies" in the context of Thailand's constitution, in comparison with other countries' constitutions. Democratization in Thailand accelerated in the 1990s. As pointed out in many previous studies, the urban middle class and traditional elite began increasingly to express their frustration with the democratically elected government, citing, among others, corrupt politicians and electoral fraud as problems. A new constitution was promulgated in 1997 with the ostensible goal of resolving these issues, and this goal has been inherited by the current 2007 constitution. "Constitutionalism" was declared a keyword of the political reform, and it was expected that the judiciary would be the institution responsible for resolving these issues. Careful examination of the 1997 and 2007 constitutions reveals that they codify various efforts aimed at constraining the National Assembly, comprising representatives of the citizens, and the Council of Ministers. In contrast to Western-style constitutionalism, in which the constitution and laws are employed to protect citizens' rights and to prevent the arbitrary use of state power while respecting democracy in the sense of rule by the majority, Thailand's constitution is structured in such a way that it enables arbitrary restriction of state power, and particularly that of the Council of Ministers, by the judiciary. Further, I point out that, as such, the 1997 and 2007 constitutions both serve to suppress the popular will that is expressed through elections.


Objective:To analyze the value of 18 F FDG PET in the diagnosis of patients suspected of having head and neck malignant tumor.Method:Seventy five cases patients suspected of having head and neck cancer or recurrence were analyzed retrospectively. 18 F FDG PET was performed in all cases.The results of some cases were compared with CT and MRI.Result: 18 F FDG PET yielded a sensitivity 91.30 % and specificity 76.92 % and accuracy 86.11 % in the diagnosis of nasopharyngeal carcinoma; sensitivity 100.00 % and specificity 83.33 % and accuracy 94.44 % in esophageal carcinoma; sensitivity and specificit and accuracy 100% in thyroid carcinoma,laryngeal carcinoma and hypopharyngeal carcinoma.Conclusion:Preliminary clinical application of 18 F FDG PET has demonstrated its significant advantages in evaluating head and neck malignant diseases.


Objective:To elucidate the effect of WT1 antisense oligonuclenotide (WT1 ASO) on apoptosis of leukemia cells and the role of WT1 gene in apoptosis of leukemia cells. Methods:K562, HL 60 cells were treated with WT1 ASO and VP 16. Then apoptosis was quantified by flow cytometric analysis assay. Results:WT1 ASO could induce apoptosis of k562 cells and the level of apoptosis increased markedly when combined with VP 16; WT1 ASO alone couldn't induce apoptosis of HL 60 cells, but it could also increase the level of apoptosis of HL 60 cells when combined with VP 16.Conclusion:WT1 ASO could increase the susceptibility of leukemia cells to VP 16 and WT1 gene may play a role in apoptosis of leukemic cells and the rule in different cells is variable, which is influenced by the type of cell.


In the late 1960s, at the invitation of Umberto Eco, Eugenio Carmi began to collaborate with Servizio Programmi Sperimentali in Rai. After some research on perception, the artist proposed an actual "transgression" for the use of television medium: using cameras not to film the reality, but to create a completely abstract color video work. From an exchange with Rai technicians, the idea was born to use in an artistic way the disturbance generated when you point a video camera at its own playback video monitor. Thus began the first Italian videoart experiments of so-called "feedback" process, to get between 1972 and 1974 to the documentary Arte elettronica, arte della luce and the video work C'era una volta un re, and then, in 1977, the animated fairy tale Olivo verde vivo created by the painter's daughters Antonia and Francesca Carmi with Giulio Masoni.


The objective of the present study was to enhance the regeneration ability of an injectable bone regeneration composite (IBRC) by the controlled release of recombinant human bone morphogenetic protein‐2 (rhBMP‐2). The IBRC comprised nano‐hydroxyapatite/collagen (nHAC) particles in an alginate hydrogel carrier. First, bovine serum albumin (BSA) as a model protein was released from IBRC to evaluate its release rules. The results suggested that IBRC is a good controlled release carrier for BSA in the range 5–75 µg/ml. In the in vitro study the rhBMP‐2 released from IBRC was determined by an enzyme‐linked immunosorbent assay specific for rhBMP‐2. The bioactivity of the released rhBMP‐2 was evaluated through differentiated function of marrow mesenchymal stem cells (MSCs), as measured by alkaline phosphatase activity. The results of an in vitro study confirmed that rhBMP‐2 released continuously for 21 days, and its bioactivity was well preserved during this period. The bone formation ability was assessed using a rat calvarial defect model of critical size. Micro‐computed tomography (micro‐CT) and histological analysis demonstrated that the IBRC had good bone formation ability, which was promoted through rhBMP‐2 released from IBRC/rhBMP‐2. In vitro and in vivo studies suggested that the present system is a potential bone critical defect repair material for clinical applications. Copyright © 2011 John Wiley & Sons, Ltd.


The diagnosis of depositional environments is essential to facies analysis and hence to the search for porous reservoir formations. Modern sedimentary environments tend to generate characteristic vertical sequences of grain size and sedimentary structures. SP and gamma-ray logs can reflect grain-size profiles. Certain log patterns thus can help to identify the environments of sand bodies. Ideally these must be integrated with paleoecologic studies and sedimentologic core logs. Where such data are inadequate or absent, additional useful information includes the presence or absence of glauconite and carbonaceous detritus. Easily recognized in ditch cuttings, these indicate marine/nonmarine and low/high-energy environments, respectively. Integrated with gamma-log patterns th se criteria define some characteristic North Sea facies models.


The results of long-term investigations on the influence of the origin of paternal cucumber forms on some economic characters are given.


Cutaneous injury in mice drives transient TLR7- and TLR9-mediated production of type I interferon by plasmacytoid dendritic cells, which is required for re-epithelialization of the skin.


The structure of light sensitivity centers is investigated by Small angle X-ray scattering techniques (SAXS). The functions of particle size distribution Dm(d) are computed from SAXS intensity curves. The model of a Ag2S particles structure both in initial colloid and after introduction in the AgBr emulsion is suggested. Some peculiarities of clusters' structure change in sensitization process are revealed.


Strategies to manipulate the surface plasmon-enhanced transmission in a near field optical readout system to achieve super-resolution are investigated. Our numerical simulations demonstrate that modulation and confinement of the plasmon-assisted effects in the readout system can be accomplished through appropriately placed "plasmon pits." It is found from the simulation results that using short metallic strips embedded in a thin dielectric film instead of a thin metal film for the data structure can aid in localizing the plasmonic effects, thereby improving the resolution of the readout system. In the simulated geometries considered, resolution up to ∼λ∕5 is achievable.


Abstract : The extent of buried munitions and explosives of concern (MEC), or unexploded ordnance (UXO), creates a serious environmental hazard in the U.S., especially where military bases and ranges are being converted to civilian use (millions of acres). The cleanup of these sites presents a formidable challenge to DoD, most prominently in terms of accurate and reliable detection and classification. Discrimination between MEC and relatively safe background clutter (scrap metal) is a monumental problem that depends on the instrument technology, as well as on the processing methodology that inverts the detection data to infer MEC. Reducing the number of false alarms in the detection process can save billions of dollars in the cleanup effort. That process and the consequent savings rely in large part on precise three-dimensional positioning (geolocation) of the detection sensors both to aid in the inversion of the data in post-survey data processing and in the mapping and recovery of locations with positive identification. Although the detection instrument technology has advanced significantly in the last decade, it is often still the geolocation technology that defines or limits the accuracy of MEC detection. The objective of this project was to develop and test novel geolocation algorithms applied to scenarios typical of MEC detection and recovery, where the precision goals are 1 cm and 10 cm for three-dimensional positioning of magnetic and electro-magnetic detection devices. The principal geolocation system was assumed to be based on inertial measurement units (IMUs) integrated with differential GPS. The GPS receiver presumably is of geodetic quality commensurate with the precision goals and serves as the reference system.