We report the synthesis of a novel class of low band gap copolymers based on anacenaphtho[1,2-b]quinoxaline core and oligothiophene derivatives acting as the acceptor and the donor moieties, respectively. The optical properties of the copolymers were characterized by ultraviolet-visible spectroscopy while the electrochemical properties were determined by cyclic voltammetry. The band gap of these polymers was found to be in the range 1.8-2.0 eV as calculated from the optical absorption band edge. X-ray diffraction measurements show weak pi-pi stacking interactions between the polymer chains. The hole mobility of the copolymers was evaluated using field-effect transistor measurements yielding values in the range 10(-5)-10(-3) cm(2)/Vs.


Increasing competition in the global market and high consumer expectations for quality products, encourage companies to produce quality products of international standards. The rubber industry is part of an industry group that is prioritized in its development in Indonesia. Based on these conditions, companies are always required to develop quality management systems that exist in the production process. The purpose of this study is to analyze the application of the quality management system of the crumb rubber industry to the ISO 9001: 2015 certification standard. The analysis was carried out on case studies and discussions with leaders of crumb rubber companies in Padang City. The success of the implementation is affected by indicators that influencing in ISO 9001: 2015 certification standards. Based on the results of the case study it can be seen that PT B has implemented an integrated quality management system in the company's business processes. On the other hand, PT A still needs much improvement in implementing an integrated quality management system and integrated with the company's business processes. It can be concluded that a strong top management commitment is not supported by the application of a quality management system. The implementation of a quality management system has not been optimally demonstrated by the company's quality control documentation system is still incomplete and the company has not involved all aspects of the company in the implementation of quality management systems.


The present invention provides a technique capable of securely fastening a first member and a second member. A first member formed on the cylindrical portion, a hole is formed in the second member, the cylindrical portion of the first member of the press-fit hole of the second component. Large diameter of the inscribed circle here, so that the cross section perpendicular to the external cylindrical portion of the shaft diameter ratio of the circumscribed circle of the hole cut vertically in the cross section of the shaft. A small diameter such that the diameter of the circumscribed circle of the cylindrical portion is cut perpendicular to the axis of the inner cross-section ratio of the inscribed circle of the hole perpendicular to the axis of the external cross-section. On one of the higher hardness of the cylindrical portion and the side surface of the hole, a tapered portion formed on an end portion of press-fitting is located in front of the side surface of the tapered portion is inclined with respect to the axial direction.


A survey was conducted on the incidence of transmissible venereal tumors (TVT) in dogs during August 2013 – July 2015. A total of 278 cases were reviewed and the incidence of genital transmissible venereal tumour (97.13 per cent) was more than the extra-genital TVT (2.87 per cent). The incidence was more common in Non-descript dogs (38.84 per cent) followed by chippiparai (21.58 per cent). Female dogs were found to be more affected (58.88 per cent) than male dogs (41.11 per cent). Extra-genital transmissible venereal tumour was more in male (87.50 per cent) than in female dog (12.50 percent). Age wise incidence was in 2-3 years (22.01 per cent) followed 3-4 years (17.61 per cent).


Molecular genetic analysis of a cryptic unbalanced translocation in two siblings with autism Christy Moore, Pamela Flodman, Moyra Smith Pediatrics, UC Irvine, Orange, CA, United States, UC Irvine, Orange, CA, United States We undertook molecular genetic studies on two siblings diagnosed with autism whose phenotypes vary drastically. The younger female is much more severely affected and has very little speech. The older male has some speech, but shows greater deficits in social behavior. At the time that the family members enrolled in the research study, blood samples were obtained from both the brother and sister for genetic analysis. Based on clinical testing prior to entering the research project in 2000, both siblings' chromosomes were visualized and believed to be normal. Recent microarray analysis using the Affymetrix Genome-Wide Human SNP Array 6.0 revealed abnormal copy number changes, showing that each sibling carries a duplication on chromosome 2 of approximately 5 MB of material derived from 2 pter to 2p25.2. They also have a deletion that encompasses approximately 4 megabases and extends from the 12p telomere to the breakpoint 12p13.32 FISH analysis confirmed this to be an unbalanced translocation. The breakpoint on chromosome 2 occurs within 2p25.2. Within this duplicated region, one gene of interest is SNTG2, coding for syntrophin G2, a cytoplasmic peripheral membrane. The breakpoint on chromosome 12 occurs within 12p13.32.


The next generation of information systems will require the development of special-purpose processors that can accommodate computation-intensive algorithms at superhigh speeds. Design methods based on field-programmable gate arrays (FPGA), which can guide the fabrication of special-use processors at lower cost than ad hoc design methods, are attracting increased attention. However, special-purpose processors based on FPGA have the problem of poor performance compared to processors designed by ad hoc methods. In this article, we propose to eliminate this problem with FPGA processors by using field-programmable VLSI (or FPVLSI) arrays of processing elements in which data transfer takes place between nearest-neighbor processors only, direct allocation of control/data flow graphs, and bit-serial architecture. Furthermore, we show that when this FPVLSI approach is used to implement a 16-point FFT, the resulting processor module is over 20 times faster than a currently available FPGA module with the same area. © 2004 Wiley Periodicals, Inc. Electron Comm Jpn Pt 2, 87(7): 28–37, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/ecjb.10076


TERTIARY FORMATIONS FROM BORE HOLE SZCZECIN IG I IN THE LIGHT OF MICROPALAEONTOLOGICAL EXAMINATIONS Summary The present paper deals with the results of micropalaeontological examinations of the Tertiary formations pierced by the bore hole Szczecin IG-I in the Polish Lowland area. On microfaunistic analysis, the author has distinguished here the Miocene deposits (depth 50,50÷126,00m), Middle Oligocene (Rupelian) deposits (depth 126,00÷127,00 m), and Upper Eocene deposits (depth 190,00÷281,00 m) that rest under the Quaternary strata. Tertiary formations resting below 281 m are examined from the palaeobotanical point of view only, since the coal-bearing deposits representing these formations do not contain microfauna. The Eocene formations pierced by the bore hole here considered, are characterized by not too rich foraminifer fauna represented by Hastigerina micra ( Cole ), Cibicides westi ( Howe ), Cibicides carinatus ( Terq .) emend. le Calve'z , Trifarina wilcoxensis ( Cush . Et Pont .) and others, and by very abundant radiolarians. The richest foraminifers are Rupelian deposits containing such index species as Turrilina alsatica ( Andreae ), Rotaliatina bulimoides ( Reuss ), Alabamina tangentialis ( Clod .), Alabamina perlata ( Andreae ) and others. The Miocene deposits resting higher up are characterized by poor foraminifer microfauna. Here are found only few representatives of Uvigerina asperula Czjzek , Globigerina bulloides d'Orb ., Stilostomella longiscata ( d'Orb .) and others, and fairly abundant diatoms ( Coscinodiscus sp.). Since the richest foraminifer material has been supplied by the Rupelian formations, the present author compares the Rupelian microfauna from Szczecin with that from certain bore holes made in West Poland, previously described by H. Wolanska (1964), and with the Rupelian microfauna cited by German authors (C. Ellerman, 1958; J. Indans, 1958; D. Spiegler, 1960; Y. Kiesel, 1962; Table 1). Table 2 shows the age extent of the more important foraminifers that occur in the Rupelian pierced by the bore hole Szczecin IG I. Normal 0 21 false false false PL X-NONE X-NONE /* Style Definitions */
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The variety of soil NH+4-N,NO-3-N,available phosphorus(P),organic matter and pH in Pinus elliottii plantations of different ages(5,10,15 and 20 years-old)were studied.The results showed that the content of available nitrogen(NH+4-N+NO-3-N)in the soil increased gradually with increase of the stand age of Pinus elliottii plantation.With increase of stand age,the content of available P and organic matter in plantation soil decreased continuously,then organic matter of 20 years old plantation was slightly high than others.The pH increased at first and then declined slowly in soil of Pinus elliottii plantation.The differences of these soil nutrients among different layers were obvious(the upper content was higher).It could be suggested that phosphor manure and lime should be applied into the soil of some years old artificial pure Pinus elliottii Engelm.plantation to improve soil nutrient.


"As late as the days before World War Two, a professional historian who carried his lectures up to his own time was deemed rash and unhistorical; a professional historian who wrote on contemporary events was considered to have lapsed into journalism; a professional historian who took part in events and wrote about them later was a rarity. Most scholars still felt that a generation or so was required before current events underwent the seal of change into history. Today, however, few American universities would hesitate to offer courses which start with World War Two and end with yesterday's newspaper. Only the most ascetic scholars now object to attempts to write serious accounts of the very recent past. And contemporary history has inevitably brought along with it eyewitness history as a vital component*'1.


(54) METHOD AND APPARATUS FOR (52) U.S. Cl. CUSTOMIZED RENDERING OF CPC ............. H04N 7/165 (2013.01); H04H 20/106 COMMERCIALS (2013.01); H04H 60/46 (2013.01); H04H 60/65 (2013.01); H04N 21/25891 (2013.01); H04N (75) Inventors: Anthony A. Shah-Nazaroff, Santa 21/.458 (2013.01); H04N 2 1/812 (2013.01) Clara, CA (US); Jean M. Goldschmidt (58) Field of Classification Search Iki, San Jose, CA (US); Kenneth A. USPC ...................................................... 725/32 36 Moore, Ben Lomond, CA (US); David See application file for complete search history. N. Hackson, Sunnyvale, CA (US); Eric O. Smith, Scotts Valley, CA (US) (56) References Cited


Theories of Taste attempt to conceptualize the processes of signification by which cultural forms have meaning and are made to mean, and how subjects and groups of subjects insert themselves and are inserted into such processes. This article argues that any working theory of taste must explain the individual, group, and social originations of cultural "choice," and the consumptive, communicative, and affective enactments or objectifications of taste. In order to do so, such a theory must conceptualize taste as functioning within ongoing struggles over the placement of cultural forms within the continually reforming hierarchies of social space.


In this paper we prove that for a generic game the linear tracing procedure is a compact one-dimensional piecewise C 1 manifold with boundary. This means that the linear tracing procedure consists of a nite number of paths and loops formed by a union of arcs and loops. Using a well-chosen transformation of variables, this enables us to formulate an everywhere diierentiable homotopy function, whose zeros describe the linear tracing procedure. The linear tracing procedure deenes a unique feasible path. Because of diierentiability we can use fast methods to follow that path and to compute the Nash equilibrium selected by the linear tracing procedure. Numerical results show that ...


Mobile applications are becoming increasingly used. Mobile devices are becoming indispensable for the user. In the material are claiming the sales of mobile devices internationally and the use of mobile applications compared to traditional internet use on desktop systems for the United States. Are presented influences the quality of mobile applications and based on these influencing factors built a model of choice for optimal application of mobile applications and traditional desktop application. At the end of the material presented methods to increase quality by tracking the influence factors during the development of mobile applications.


Catheter-related blood stream infections in the intensive care unit (ICU) are common, costly, and potentially lethal. The Dec 28, 2006, issue of The New England Journal of Medicine reported that an evidence-based intervention in 103 intensive care units in the Michigan Keystone ICU programme had resulted in a large sustained reduction in rates of these infections. The study was widely reported in the popular media and elsewhere as a triumph of the "simple checklist" as a solution to patients' safety problems. Yet the widespread interest in this study is a dual-edged sword. It was a great story. Science often needs to be simplifi ed for the lay public. The problem is that the story may well have been oversimplifi ed. The emphasis on checklists is a Hitchcockian "McGuff an", a distraction from the plot that diverts attention from how safer care is really achieved. Safer care is achieved when all three—not just one—of the following are realised: summarise and simplify what to do; measure and provide feedback on outcomes; and improve culture by building expectations of performance standards into work processes. We propose that widespread deployment of checklists without an appreciation of how or why they work is a potential threat to patients' safety and to high-quality care. Attributing the reduction of infection in the Keystone programme solely to the use of checklists is an easily made but crucial mistake. Checklists are a good way of making certain that tasks get done, as anyone who has taken a shopping list to the supermarket can testify. If wise, checklists can help workers perform a task by reducing ambiguity about what to do. Of course, determining the best way of proceeding in a complex health-care setting is not as straightforward as producing a prompt to remember the milk. But fi guring out what should form the content of a checklist for a clinical problem is a nonetheless achievable ambition: there are well-defi ned processes for identifying and synthesising research evidence. For the Keystone programme, interventions with a potential to improve outcomes were identifi ed, and the fi ve procedures that had the strongest evidence and the lowest barriers to implementation were selected and converted into a standardised checklist. But checklists, even if based on rigorous evidence, have never penetrated medicine in the way they perhaps ought to have. The reasons for this are primarily social and cultural. In part, the way that physicians are socialised creates resistances and interferences to the use of checklists. Some come to feel that checklists undermine their claims to expertise, are infantilising, and an unnecessary impediment to the swift decision making and action required for eff ective care. How to understand and disrupt these deeply entrenched norms is a much greater challenge than identifying the components of a checklist. The mistake of the "simple checklist" story is in the assumption that a technical solution (checklists) can solve an adaptive (sociocultural) problem. To improve safety, health care needs to get the technical and adaptive work right. Without attention to adaptive work, checklists would probably suff er the same fate as guidelines—often left unused, even when very robust. Summarising evidence is a necessary but not suffi cient step for translating evidence into practice. Evidence summaries need to be combined with an understanding of, and a strategy for, mitigating the technical and social/political and psychological (even emotional) barriers to using the evidence, and with feedback about performance. Emphasising checklists as the explanatory mechanism for the reduction in catheterrelated infections obscures the complex labour necessary to create a collective local faith in checklists. How support was mobilised for coordinating work around infection control is the real story of the Keystone ICU project. What happened in Michigan involved the creation of social networks with a shared sense of mission, whose members were each able to reinforce the eff orts of the other to cooperate with the interventions. Implementing the entire programme occurred over 9 months—it was not simply the case that the units were handed the checklist and immediately fell in line. The work was arduous and often laden with emotions. Before ICU units were allowed to take part in the intervention, each hospital had to assign a senior executive to work with participating units. Each ICU was required to identify a physician and nurse team leader. The executives were required to meet monthly with unit Co bi s


Objective: To analyze the relationships between the expressions of P170、LRP、GST-π,clinical stage,and chemotherapy efficacy in NSCLC.Methods: Three kinds of multidrug resistance(MDR) protein in peripheral blood lymphocyte of 82 cases of NSCLC were examined by immunohistochemistry(IHC) and the correlation with chemotherapy effects were analyzed.Results: The response rate of Chemotherapy was 9.8% for positive expression of P170;15.6% for positive expression of LRP;13.6% for positive expression of GST-π .Conclusion: The efficacy of chemotherapy is Low in NSCLS with the positive expressions of P170、 LRP、GST-π.[


Hydrocarbons as reductants show promising results for replacing NH3 in SCR technology. Therefore, considerable interest exists for developing low-temperature (<200 °C) and environmentally friendly HC-SCR catalysts. Hence, C2H4 was examined as a reductant using activated-carbon-supported MnOx-based catalyst in low-temperature SCR operation. Its sensitivity to Mn concentration and operating temperature was parametrically studied, the results of which showed that the catalyst activity followed the order of 130 °C > 150 °C > 180 °C with an optimized Mn concentration near 3.0 wt.%. However, rapid deactivation of catalytic activity also occurred when using C2H4 as the reductant. The mechanism of deactivation was explored and is discussed herein in which deactivation is attributed to two factors. The manganese oxide was reduced to Mn3O4 during reaction testing, which contained relatively low activity compared to Mn2O3. Also, increased crystallinity of the reduced manganese and the formation of carbon black occurred during SCR reaction testing, and these constituents on the catalyst's surface blocked pores and active sites from participating in catalytic activity.


In this paper a model of the Self Excited Dual Star Induction Generator in an autonomous operation is presented. The model developed to study the dynamics of the Dual Star Induction Generator is based on the model of R. H Park. The knowledge of the magnetic characteristic and its mathematical model are required. The model is then used to analyze the static and dynamic performances of the generator. An application as an autonomous generator under balanced and unbalanced operation supplying various types of loads is simulated. The results obtained by simulation are presented and discussed.


In this paper, to segment the regions of the color image for recognition and to solve the problem of noise, spatial characteristics of image are proposed. Also to reduce the number of colors, histogram techniques are used. The results of the proposed region segmentation algorithm are compared with the results of the clustering technique and shows that the proposed algorithm makes much better region segmentation of the color image.


Alcoholics Anonymous (AA) has long been the major treatment of choice in the United States for individuals with alcohol related problems. Research on AA has had methodological problems and there is no clear evidence that AA in and of itself is effective in treating alcohol problems. Treatment studies on alcohol and substance users have found that abstinence self-efficacy and approach coping skills have been related to improved drinking outcomes. Also, depression and alcohol problems have been shown to be highly correlated with each other. Therefore, this study examined the relationship between participation in AA and improvements in abstinence self-efficacy, learned helplessness, and depression. One hundred and four individuals who enrolled in inpatient treatment for alcohol dependence were assessed at admission for depression, self-efficacy, learned helplessness, and alcohol-related problems. These were also assessed at end of treatment and 2 month follow-up along with participation in AA. Minimal findings were found for the impact of AA on any psychosocial variables. v Alcoholics Anonymous


Purpose: TO STUDY AND COMPARE THE INTRA-OPERATIVE AND LONG TERM POST-OPERATIVE COMPLICATIONS WITH PENETRATING (TRABECULECTOMY) VS NON PENETRATING (DEEP SCLERECTOMY) GLAUCOMA SURGERY Methods:In this study, 35 eyes underwent trabeculectomy (group A)and 35 eyes underwent deep sclerectomy (group B). The unaided visual acuity, best corrected visual acuity, slit lamp examination to assess the anterior chamber depth, hyphaema, hypotony, blebitis, choroidal detachment, filtering bleb morphology and functioning, cystoid macular oedema, endophthalmitis etc. gonioscopy was performed, fundus evaluation using 78D/90D/20D indirect ophthalmoscopy , visual field examination, Applanation tonometry to evaluate the intra ocular pressure was performed at 1st day, 1 week, 1 month, 3 month, 6 month, 1 year and 7 year postoperatively Results: The complications were divided into intra-operative, early postoperative and late postoperative time. 2 patients from group A suffered intraoperative hyphaema whereas none encountered the same intraoperatively in group B. In the early postoperative period, the most common complication seen with group A patients was shallow anterior chamber and hyphaema and was seen in 25% of the patients whereas the commonest early postoperative complication among group B patients was seen to be severe anterior chamber inflammation which was seen in 15% of them. The late onset complications included loss of >1 line vision on snellen's chartin 25% of group A patients, followed by occurence of cataract in about 20% of them, 3 patients presented with marginal increase in the IOP who were later started on one group anti glaucoma medication. 2 patients from group B had persistently elevated intra ocular pressure for which Nd Yag assisted goniopuncture was performed. Loss of >= 1 line vision on snellen's chart was also noted in 1 patient. Other late onset complications included blebitis, severly vascularised bleb, failure of the filtering bleb and hypotony maculopathy, 7 patients from group B had to undergo conventional trabeculectomy with application of MMC due to very high intra ocular pressure. Conclusion : Our study observed that although both the penetrating and non-penetrating surgeries significantly lowered the IOP in patients with primary open angle glaucoma, the patients who underwent standard penetrating surgery (trabeculectomy), i.e. group A, encountered significantly more number of complications as compared to the patients falling under group B.


Goldman, McCarthy & Peavey (1979b) argued that growth rates of phyto-plankton in apparently oligotrophic ocean waters may near maximal. Their hypothesis was succinctly restated by Goldman (1980): '…the chemical composition of phytoplankton is extremely variable under exacting laboratory conditions of nutrient limitation and approaches the 'Redfield' proportions (C:N:P of 106:16:1) when neither nitrogen nor phosphorus is limiting so that near maximal growth rates are attained. In marine surface waters the chemical composition of particular matter often is in the Redfield proportions, thus implying that natural phytoplankton growth rates may be close to maximal.' We argue on theoretical, experimental and observational grounds that this implication may not necessarily be correct.


In Cui et al. (2017), the name of PSR J0735−6301 should be revised to PSR J0735−6302 all through the text, tables, and figures. In Table 2, we incorrectly labeled some uncertainties in the R.A. and decl. solutions. To be more specific, in J0735−6302, we have: R.A. 07:35:5(2) (incorrect) to 07:35:05(20) (correct); decl. −63:02:0(4) (incorrect) to −63:02:00(40) (correct). In J1739 −2521, we have: decl. −25:21:2(2) (incorrect) to −25:21:02(20) (correct). Given that all discussion results and conclusions remain unchanged, Table 2 is the main correction needed for Cui et al. (2017). The Astrophysical Journal, 848:72 (3pp), 2017 October 10 https://doi.org/10.3847/1538-4357/aa8d77


In Thailand, both aand P-thalassemia are widespread and there is more than one subtype in each variety. Hemoglobin (Hb) E which is a2, p;6G'u+Lys (Hunt & Ingram, 1959) is remarkably frequent (Na-Nakorn et al . , 1956; Sundharagiati et al., 1958, 1959a, 1959b; Flatz et al., 1965; Wasi et al., 1967a), reaching 50 percent in certain areas. These abnormal genes in different combinations result in a spectrum of syndromes ranging from asymptomatic heterozygotes to lethal H b Bart's hydrops fetalis. Attempts have been made to characterize the various genotypes by clinical, hematologic, biochemical, genetic and cord blood studies. This paper summarizes the manifestations of these syndromes, with particular emphasis on the diseased forms.


This article examines the introduction of Google Street View in Australia, and the subsequent 'payload data' collection scandal. Through this case study we consider the privacy implications of Street View and the various regulatory discourses that have emerged around this Google service in Australia. We argue that, while privacy by design (PBD) is one of the most commonly advocated methods of privacy protection in Australia, its implementation carries a number of significant limitations. The March 2014 introduction of the Australian Privacy Principles holds some promise, but it still views privacy as a compliance issue rather than a rights issue. We suggest that the introduction of a broad statutory right to privacy could ensure fuller privacy protections for end-users of Street View and other location-based services.


The class of inflated beta regression models generalizes that of beta regressions [S.L.P. Ferrari and F. Cribari-Neto, Beta regression for modelling rates and proportions, J. Appl. Stat. 31 (2004), pp. 799–815] by incorporating a discrete component that allows practitioners to model data on rates and proportions with observations that equal an interval limit. For instance, one can model responses that assume values in (0, 1]. The likelihood ratio test tends to be quite oversized (liberal, anticonservative) in inflated beta regressions estimated with a small number of observations. Indeed, our numerical results show that its null rejection rate can be almost twice the nominal level. It is thus important to develop alternative testing strategies. This paper develops small-sample adjustments to the likelihood ratio and signed likelihood ratio test statistics in inflated beta regression models. The adjustments do not require orthogonality between the parameters of interest and the nuisance parameters and are fairly simple since they only require first- and second-order log-likelihood cumulants. Simulation results show that the modified likelihood ratio tests deliver much accurate inference in small samples. An empirical application is presented and discussed.


Catalytic reforming of natural gas is a commercial process to produce syngas,which is the main source for the production of am-monia,methanol,hydrogen,and many other important products.This method produces also large amounts of CO2 as by-product.Chemical-looping reforming(CLR)is a novel technology that can be used for syngas production by partial oxidation and steam reforming of hy-drocarbon fuels.One key issue with the CLR concept that is being widely studied is the oxidation and reduction behavior of potential oxygen-carrier materials.Four perovskite-based nano-composite oxides were prepared by the sol-gel method and characterized by X-ray diffraction,N2 adsorption-desorption,scanning electron microscopy(SEM),and CH4 temperature-programmed surface reaction.The catalytic per-formance of the prepared samples for CLR of CH4 to syngas was investigated.The results showed that the LaMO3(B = Cr,Mn,Fe,and Co)oxides possess perovskite-type nano-composite structure.The oxidizing ability of these four perovskite oxides follows the order of LaCoO3 LaMnO3 LaFeO3 LaCrO3.Among them,LaFeO3 oxide has higher activity for CLR of CH4 to syngas.The CH4 conversion and CO selec-tivity are 89.6% and 98.9%,respectively.Especially,the sequential redox reaction revealed that the LaFeO3 oxide exhibits high stability with CH4 conversion of 60%~70% and CO selectivity of ~98% after 10 redox cycles.The SEM analysis revealed that the structure of the LaFeO3 oxide was not dramatically changed before and after 10 cyclic reactions.


Seeking certified reading sources? We have the general theory of employment interest and money to review, not only read, yet additionally download them or even review online. Discover this terrific publication writtern by by now, simply right here, yeah only right here. Get the data in the types of txt, zip, kindle, word, ppt, pdf, and also rar. Once again, never ever miss out on to read online and download this book in our website right here. Click the web link. Searching for a lot of marketed book or reading resource worldwide? We supply them all in layout type as word, txt, kindle, pdf, zip, rar and ppt. one of them is this competent the general theory of employment interest and money that has been written by Still confused ways to get it? Well, simply check out online or download by signing up in our site right here. Click them. Our goal is always to offer you an assortment of cost-free ebooks too as aid resolve your troubles. We have got a considerable collection of totally free of expense Book for people from every single stroll of life. We have got tried our finest to gather a sizable library of preferred cost-free as well as paid files. GO TO THE TECHNICAL WRITING FOR AN EXPANDED TYPE OF THIS THE GENERAL THEORY OF EMPLOYMENT INTEREST AND MONEY, ALONG WITH A CORRECTLY FORMATTED VERSION OF THE INSTANCE MANUAL PAGE ABOVE.


The number of older siblings a child has is negatively correlated with the child's verbal skills, perhaps because of competition for parents' attention. In the current study, we examined the role of siblings' sex and age gap as moderating factors, reasoning that they affect older siblings' tendency to compensate for reduced parental attention. We hypothesized that children with an older sister have better language abilities than children with an older brother, especially when there is a large age gap between the two siblings. We reanalyzed data from the EDEN cohort (N = 1,154) and found that children with an older sister had better language skills than those with an older brother. Contrary to predictions, results showed that the age gap between siblings was not associated with language skills and did not interact with sex. Results suggest that the negative effect of older siblings on language development may be entirely due to the role of older brothers. Our findings invite further research on the mechanisms involved in this effect.


The molecular pathology underlying the development and progression of ductal pancreatic adenocarcinoma is poorly understood relative to that of other major cancers in industrialized societies. The frequency, nature, and distribution of p53 abnormalities, their temporal relationship to the metastatic and clinicopathologic phenotypes of sporadic and familial pancreatic cancer, and their consequent effects on the genetics and expression of critical wild‐type p53‐regulated genes (mdm‐2 and p21/WAF‐1) warrant examination in pancreatic adenocarcinoma. This molecular and immunochemical study of the p53, mdm‐2, and p21/WAF‐1 genes and gene products examined the largest series of nonneoplastic, neoplastic, and metastatic ductal pancreatic lesions reported to date in relation to clinicopathologic profile.


Embarks from the system viewpoint,combine with teaching practice,this paper discusses the teaching method of "seizes the enemy fist",the author thinks language method,direct-vision method,integrative method;and decomposition method,and method of prevention and correcting errors are effective methods for teaching,they can give some references for improving teaching quality.


This article deals with the theme of teacher training from the historical and theoretical perspectives. In the first part, the historical focus is introduced and the trajectory of teacher training in Brazil is examined, dividing it into six periods beginning with the passing of the Law of Schools of First Letters in 1827 and closing with the promulgation of the new law for national education in 1996. The second part deals with theoretical aspects, considering the two basic models of teacher training, their implications for the training of teachers of primary and pre-school education, the dilemma resulting from the contraposition between the two models and the way for overcoming it and concluding with observations on the training of teachers for special education.


According to the sorts of plating processes, the plating wastewater can be classified into five kinds: pretreatment wastewater, cyanide containing wastewater, chromium containing wastewater, multi-source wastewater and blended wastewater. The major source of plating wastewater and its quality of intake water was discussed. Membrane treatment process for plating wastewater was summarized. Taking three kinds of electroplating wastewater recycle projects as examples by membrane process, the process flows of plating wastewater recycle by membrane were introduced.


Computational fluid dynamics (CFD) analysis was conducted to evaluate the high-speed aerodynamics of a Gulfstream GIII airplane (Gulfstream Aerospace Corporation, Savannah, Georgia) swept wing modified with an experimental seamless, compliant flap called the Adaptive Compliant Trailing Edge (ACTE) flap for airworthiness. The high-speed aerodynamics of the modified ACTE wing were analyzed at a Mach number of 0.85 and an altitude of 40,000 ft. A polyhedral finite-volume unstructured Reynolds-averaged Navier-Stokes CFD code was used with a two-equation turbulence model. Wing aerodynamics sensitivities to lift coefficients, airplane engine operation, vortex generators (VGs)


Even though perception of electricity assumes the goods, electricity is characterized by unique, specific simultaneous production and consumption with no possibility to bank up electricity efficiently. Besides, long time is needed for construction of power system elements and for return of investment, while electricity is constantly percept as immediate public service. Market opening actualized question of supply security under new conditions. Number of market subjects dramatically increased, responsibilities are decentralized and consumer requests are significantly increased. Accordingly, the main market design task comprises optimal solution of supply security problem under new conditions between subjects with contradictorily targets. All power sectors in the region are going through turbulent processes of restructuring, market opening and privatization at the same time. Security of supply should be observed more carefully then ever on all three levels: national, regional and European. Key-Words: regional system specifics, electricity market, privatization, supply security


Research was conducted to determine levels of Cry1Ac in transgenic Bacillus thuringiensis Berliner (Bt) cotton leaves from four different commonly used bioassays. Significant differences in the amount of Cry1Ac were found among the different bioassay types. For bioassay arenas that prevented desiccation of leaf material, Cry1Ac levels remained stable for 10 d after tissue was excised from the plant. In other bioassay types, Cry1Ac levels increased in excised leaves over time because of desiccation that concentrated the transgenic protein. We conclude that careful descriptions of bioassay methodology are essential for laboratory studies documenting Cry1Ac levels and corresponding efficacy against lepidopteran pests.


MECHANICAL PROPERTIES AND PATIENT PERCEPTIONS OF COMMONLY USED CLEAR ALIGNER SYSTEMS AS-RECEIVED AND AFTER CLINICAL USE Lauren Teske, D.D.S. Marquette University, 2015 Background/Objectives: This study aimed to investigate the viscoelastic properties of two clear aligner systems, Invisalign (Align Technology, Inc, Santa Clara, CA, USA) and Simpli5 (Allesee Orthodontic Appliances, Sturtevant, WI, USA), and determine if there was a difference after use. A survey assessed patients' perceptions of the aligner material and post-treatment satisfaction. Materials/Methods: Mandibular aligners were collected from two patients after 2-3 weeks of use (n=6). Duplicate, unused aligners were obtained for each patient (n=6). Dynamic mechanical analysis (DMA) characterized the viscoelastic properties of the materials. Three tests were done on separate specimens: frequency scan (0.1-10 Hz under 25 μm displacement at 37C), creep-recovery (1 N, 2 N and 3 N at 37C) and temperature ramp (28-120C at 5C/min under 1 Hz and 25 μm displacement). The survey was given to sequential patients (n=7) after completing aligner therapy. Repeated measures of multivariate analysis of variance were performed. Results: No statistically significant difference in storage modulus, loss modulus, tan δ, creep compliance, or strain recovery was found comparing the materials in asreceived and after-use states, and no significant difference was found between Invisalign and Simpli5 (p>0.05). The tan δ (loss modulus/storage modulus) values for as-received Invisalign and Simpli5 at 1 Hz were 0.056±0.01 and 0.093±0.03. The creep compliance (μm/N) for as-received Invisalign and Simpli5 were 300±50 and 155±36. Strain recoveries were >94%. Patients' survey responses were predominately positive, as all were pleased with the esthetics, comfort, and performance of the aligners. Conclusions: While there was no significant difference between the materials before or after use, both Invisalign and Simpli5 demonstrated favorable qualities, including low tan δ values and positive patient perception of the material.


The excited exciton (S2-exciton originating from the second-excited state of the molecules) was studied by real-time spectroscopy with 30-fs pulses. The ultrafast dynamics due to the S2–S1 internal conversion process were clearly observed in the pump–probe signal. The signal was modulated by the coherent molecular vibrations with 241 ± 4 cm-1 and 319 ± 4 cm-1 frequencies. The phase of the oscillation indicates that not only the ground state but also the excited state contribute to the oscillatory signal. The excited-state wave-packet motion was explained by dynamic intensity borrowing mechanism from the S2 S0-transitions to the S1 S0-transitions.


Java's automatic memory management is the main reason that prevents Java from being used in hard real-time environments. We present the garbage collection mechanism that is used by the Jamaica Virtual Machine, an implementation of the Java Virtual Machine Specification. This mechanism differs significantly from existing implementations in the way threads are implemented, root references are found and in the object layout that is used. The implementation provides hard real-time guarantees while it allows unrestricted use of the Java language. Even dynamic allocation of normal garbage collected Java objects is possible with hard real-time guarantees.


The most general type of mechanical collector is the cyclone. For the high collection efficiency and low pressure drop in the cyclone, the effect of inlet shapes must be well grasped. In this study, performance characteristics of cyclone with various inlet shapes, such as helical, tangential and involute shapes, were experimentally investigated and compared as a function of particle size and inlet velocity. The experimental results show that the helical shape has the highest collection efficiency and pressure drop among three different inlet shapes. The collection efficiency and pressure drop with various inlet shapes and velocity changes in cyclone are graphically depicted.


Open source J2EE Application Servers (J2EE ASs) have already attracted industrial attentions in recent years, but the reliability is still an obstacle to their wide acceptance. The detail of software failures in J2EE AS was seldom discussed in the past, although such information is valuable to evaluate and improve its reliability. In this paper, we present a measurement- based failure classification and analysis. Presented results indicate open source J2EE AS's reliability needs improvement. Some notable results include: (1) the implementation of a widely used fault-tolerant mechanism, clustering, needs improvement; (2) only 15% of reported failures are removed within a week, and about 10% still open by the time we finish the study; (3) different J2EE ASs have different unreliable services so reliability improvement activities should be specific to both AS and applications.


Electricity production in Poland is carried out mainly in conventional power plants, and the necessary resources include fuel and water. Significant water intake and production of sewage necessitate the application of technological solutions limiting the negative impact on the water environment. For this reason, Tauron Group's power plants for replenishing losses in cooling circuits use beside surface water, water from inactive mining plants. Due to the increased content of chlorides and sulphates in relation to surface water, mine water show significant corrosion properties. However, they are characterized by a relatively stable chemical composition mainly dependent on the physicochemical properties of the geological environment. The surface water quality is affected by many factors, such as seasons, thaws, rainfall, or the presence of pollutants from sewage disposal. The relative stability of the chemical composition of mine water allows for easier determination of chemical dosage during treatment process. The paper presents a stability assessment of the chemical composition of waters used to supplement circuits based on data from 2007–2017.


Introduction Dairy cattle have been traditionally selected for milk production and milk components (fat and protein). The traditional approach made sense because farmers are paid for milk. Dairy selection has changed in the past decade. Secondary traits, including reproduction traits, are being included in indices by specifically decreasing the emphasis on production. Greater emphasis on non-production traits reflects the industry desire for functional dairy cattle with greater fertility. The hope is that appropriate economic weightings are placed on secondary traits so that slowed progress in milk production is offset by improved farm economics created by more functional cows. Few will argue that high fertility has value. The real question is how much value (economic weight) does it have? This later question is particularly difficult when one considers that selection indices are designed for use by the national dairy herd that is comprised of increasingly diverse production systems.


Contemporary society is faced with multiple and complex challenges. These challenges include growing inequality in the world, unprecedented levels of environmental problems and rapid advances in new technologies. These challenges present both opportunities and threats. Rosi Braidotti describes this state of affairs as a (post)human condition characterized by a predicament. The (post)human predicament relates to how one adopts the positive dimension of the (post)human condition by embracing all of life and its interconnectedness, and at the same time to how one resists the potential negative effects of advanced technologies. For decolonial scholars the complex challenges mentioned are the consequence of a colonial matrix of power, which is the legacy of colonialism. The (post)human condition and decolonial turn raise critical existential as well as educational questions such as: How should we live? What is now the unit of reference for the human? How should we learn? What knowledge is of most worth? Whose knowledge is of most worth? In this article I explore potential resonances between (post)humanism and decoloniality and propose ubuntu-currere as a concept for reimagining curriculum in the post-Anthropocene.


Anemia is a common complication of advanced chronic kidney disease (CKD). Treatment with erythropoiesis‐stimulating agents (ESAs) remains a common approach in managing anemia of CKD. The 2012 Kidney Disease Improving Global Outcomes Clinical Practice Guideline for Anemia in CKD suggests avoiding ESA therapy use to maintain Hb level above 11.5 g/dL. However, optimal Hb target range in adult patients undergoing chronic dialysis remains unknown. Clinical studies suggest risks associated with normalization of Hb levels in adult patients with CKD. In this article, we briefly review some of these studies and the concerns associated with higher Hb targets in this patient population. We also suggest a target Hb range for adult chronic dialysis patients receiving ESAs. It is currently undetermined if this target Hb range would apply to newer agents that are being studied for anemia management in this population.


Pesantren are traditional Islamic educational institutions which are never used up to be discussed and studied. One of the exciting things to study is how pesantren design basic "classes" so that they can make effective and efficient learning while staying oriented towards learning goals. And how do pesantren make "class" a secure emotional connection between teacher (kyai), student (santri), and teaching material (kitab kuning) in the class so that class harmonization appears within the typical scope of pesantren-style learning. Kitab Kuning learning in pesantren has a unique "model" in carrying out its education; this particularity is then interesting to be used as study material as another alternative in organizing education. Kitab Kuning learning in pesantren adheres to management that is different from class management in general, both in terms of curriculum structure, class construction, and interaction of existing learning components. In general, Kitab Kuning learning in pesantren is divided into 3 (three) levels, namely the primary level (Ula), the intermediate level (Wusta), and the upper level (Ulya). However, this research focuses more on the basic level (Ula), because this level is a determinant of success at the next grade level. Santri at the elementary level are not directly taught the Kitab Kuning, but were introduced first how to read and write the 'Pegon' Script. So, students who just entered were conditioned in such a way as to be more familiar with the 'Pegon' Script. Therefore, it will be discussed about the patterns and models of class management in the learning of the Kitab Kuning at As-Sunniyah Kencong Pesantren and Baitul Arqom Balung Pesantren in Jember Regency using behavior modification, socio-emotional, and group process approach, which is seen in the classroom conduciveness based on class conduciveness, the element of spirituality, namely the synergistic and harmonious interaction between the kiai, the teacher, and the santri in achieving the learning objectives.


A new sequential uncertainty domain method called SUACO is presented on the basis of ant colony optimization,which is adapted to solve complex combination optimization problems.Firstly,inverse hydrogeologic problems are transformed into combination optimization problems.Ant colony optimization is adopted to solve these combination optimization problems.Finally,two inverse hydrogeologic problems are solved by SUACO.The results show that SUACO is both effective and efficient in parameter identification.


Analysis of short message corpus is an important foundation for research of automatic short message processing technology. Based on large scale short message corpus, this paper firstly presents statistical data and performs analysis in detail on basic information of short message corpus and special language phenomena in it. The distributions of the corpus parameters and special language phenomena are also given out. The statistical results presented in the paper are meaningful for research of robust short message understanding and implementation of short message based manmachine dialog system and short message based machine translation system. And we also build an automatic error correction system on mobile phone to correct the misapplication of Chinese character in short messages. The preliminary results show that our method is effective.


This is an introductory work to the field of automatizing futures markets, related to commodities, so far operated by human traders. First, we build a mathematical framework for a futures market with many producers and consumers represented by automated traders in the market platform. Then we suggest an automatic trading strategy for the automatons. This strategy takes into account the forecasts of supply and demand streams as well as the evolution of nominal price. Later, we recall a set of analytical criteria used to measure the performance of a trading strategy. Next, we illustrate our approach by showing a price pattern generated by the automatic strategy and calculate its performances. Finally, we exhibit a heuristic based on simulation allowing to compute a quasi-optimal parameters matrix for this automatic trading system.


The method of high precision printing-quality detection on high-speed splitting machine by using machine vision principle is introduced.The system structure and the function of each structure,detection algorithms and software design are introduced in detail.The system has the feature of high precision detection and high-speed,realizes the tipping paper products'on-line quality detection on high-speed splitting machine.


The aim of this study was conducted to provide added assistant system on productiveperformance, behavioral, and blood composition of Korean native(Hanwoo) steers. A total of48Hanwoo steers(aged 18-months) were housed separately in groups of 4heads in a pen(32m2)for 10months. The steers were average ...


The spreading rate of initially closely located water particles and passive drifters in the surface layer of the Gulf of Finland is studied using autonomous surface drifters. The average spreading rate increases with the increase in the time elapsed from the deployment, equivalently, with the increase in the distance between drifters. The typical spreading rate is about 200 m/day for separations below 0.5 km, 500 m/day for separations below 1 km and in the range of 0.5-3 km/day for separations in the range of 1-4 km. The spreading rate does not follow the Richardson law. The initial spreading, up to a distance of about 150 m, is governed by the power law d ~ t 0.27 whereas for larger separations the distance increases as d ~ t 2.5 .


Objective To observe the ultrastructural changes of the lens epithelial cell in the human age-related cataract. Methods The ultrastructural of lens epithelial cell (LECs) of age-related cataract (10 cases, All were cerebral cortex cataracts. Group A for inflation time, 8 cases; group B for mature period, 2 cases.) were observed and compared by AEM-1200 type electron microscope. Results Compares with group A, The LECs in group B appeared the massive heterogeneous types nucleus, the chromatined condensability, the endosarc net expanded obviously, the filament were swelling with vacuole obviously. It's cell keel deformated, distorted, significantly reduced or disappear. Presents the phenomenon of weakly perishes obviously. Conclusion The ultrastructural changes of the lens epithelial cell play a critic role in pathogenesis of the human age-related cataract.


Background: The primary intra-abdominal synovial sarcoma is rare while the mortality is relative high. There is currently no effective treatment except surgery for this type of sarcoma. Case presentation: We report a 66-year-old female patient with intra-abdominal synovial sarcoma. A huge mass lesion was found in the abdomen. Computed tomographic (CT) scanning and pathological examination cannot determine the origin of tumor. The histologic examination of detected biphasic pattern comprised epithelial and spindled cells in mitotic figures, which was consistent with synovial sarcoma. However the origin of the tumor is uncertain. Conclusion: Intra-abdominal synovial sarcoma has unique characteristics that need to be further investigated in order to understand the underlying molecular mechanism, pattern of development and metastasis, and thereby establish effective treatment strategy.


We have measured impact ionization rates in Ga1−xAlxSb at x=0 and 0.08. For these Al contents, the ratio values of the spin‐orbit splitting energy Δ to the energy gap Eg are, respectively, greater and lower than unity. We have determined that the ratio of the ionization coefficients kp/kn is greater than unity for both compositions and that it is much lower (kp/kn≊2) than the value (≳10) determined on our layers for x=0.04. Multiplication noise measurements confirm these results. The comparison to other published data show that the ionization in these antimonide compounds is not yet elucidated.


This paper is based on the monitored data and the related data on Zhengzhou's city traffic noise condition in the 1994-1998 period. And, under the help of Grey system theory and through the establishment of GM(1,N)predicting model, it has made a predicting of Zhengzhou's city road traffic noise condition prior to the year 2010. Considering the related data on city road traffic noise condition, the paper derive the major factors causing noise by empolying Grey correlation analysis method, and thus put forward the countermeasures in the 1999-2010 period.


This article presents a methodology for testing high-performance pipelined circuits with slow-speed testers. The technique uses a clock timing circuit to control data transfer in the pipeline in test mode. The technique adds no extra hardware in the data path of the pipeline and therefore has virtually no performance penalty. A clock timing circuit capable of achieving a timing resolution of 50 ps in 0.18 μm CMOS technology is presented. The design provides the ability to test the clock timing circuit itself. The effectiveness of the technique is demonstrated using a 16-bit pipelined multiplier as a test vehicle. Simulations show that we are able to detect delay faults as small as 50 ps at an input clock frequency of 100 MHz.


Nonlinear studies extend to vast areas in the fields of natural and social sciences. In public policy, nonlinear studies are also making their way to observe various nonlinear phenomena, providing information that the traditional linear applications are not capable of providing. Yet, teaching public policy through nonlinear models still is not widely accepted in most institutions of higher education despite the in-depth and vast information that these models uncover. This is because most institutions of higher learning are constrained by top-down hierarchal systems that promote control and linear observations. This article addresses the problems and limitations of the current linear methods in teaching public policy in most institutions of higher learning. It then offers a nonlinear model in teaching public policy and the benefits gained through the application of such model in studying the subject.


Recently discovered pyrochlore oxide, Hg 2 Ru 2 O 7 , shows a first order metal–insulator transition at T ∼107 K. The effect of hydrostatic pressure on the M–I transition was studied by measuring the temperature dependent resistivity ρ( T ) up to 12 GPa. The application of pressure suppressed the low temperature insulating state and eventually induced a transition from a correlated insulator to a metal at around 5 GPa. With decreasing temperature, ρ( T ) in the metallic phase showed a rapid decrease at around T * ∼40 K, likely representing the onset of a coherent–incoherent crossover, and eventually a well defined T 2 -dependence at low temperatures, indicative of the presence of coherent quasi-particles. All these results point the formation of a Fermi liquid with an enhanced mass in the metallic state of this geometrically frustrated system, located close proximity to the correlation driven metal–insulator transition.


Studies confirm that burnout has negative effects on education career students. For these motives, present study aims to identify the relationships between the burnout components (emotional exhaustion, cynicism, student effectiveness) and the academic self-regulation, the academic postponement and academic performance, in university students of the initial education career. The sample was of 148 students (100% women) between 16 and 52 years old $(M_{age}=26.2\theta, SD=6.53)$ from the first to the third year of studies of the initial education career of a private university of Lima–Peru. The results demonstrated that the cynicism predicts to the academic postponement $(\beta=.27,p\lt\theta 5)$, and negatively predicts to the academic self-regulation $(\beta=-.24,\ p\lt\theta 1)$. Then, the student effectiveness negatively predicts to the academic postponement $(\beta=-.25,\ p\lt\theta 1)$, and predicts to effectiveness negatively $(\beta=.44,\ p\lt\theta\theta 1)$. Finally, academic postponement negatively predicts the academic performance $(\beta=-.22,p\lt\theta 5)$.


A new constitutive model was developed to describe the deformation mechanism,microstructure evolution and mechanical response of bulk nanocrystalline materials using the energy approach to systematically describe the grain size,strain rate and defect development dependent mechanical characteristic of bulk nanocrystalline materials.In this model,the grain and the grain boundary were taken as an integral object to sustain dislocation and accommodate grain boundary sliding mechanisms.Nanocrystalline Ni samples tested by different strain rates and grain sizes were prepared to test the applicability of the developed model.Compared with the experimental data,the predicted model can describe the mechanical response of bulk nanocrystalline materials.


Along with the development of technology, there are a number of influences in the lives, such as in the field of agriculture, health, service and more. One of the effects of technology in health area is in medical devices which are increasingly integrated with software and hardware. All of that have aim to help relieving the burden of people or users in the application, one of it is in determining the nutritional status of children in the Posyandu. The Prototype System of Toddlers Nutritional Status Assessment based on Anthropometric Index Using Fuzzy Logic in Posyandu. This tool has been integrated with software designed using Borland Delphi 7 through serial communication with Arduino. The results of nutritional status assessment system will be displayed on PC / laptop, so that it can be easier for cadres of Posyandu. Whereas the appearance in the devices is on the LCD, it is in the form of weight and height value of the toddlers. The maximum workload of this prototype is the children aged 2-5 years with a maximum weight of 20 kg and a maximum height of 120 cm. Percent average error in the measurement of height sensor is 0.4953 while the measurement weight sensor is 0.0933 . The nutritional status of children aged 2-5 years in the Jember Lor village average is good nutrition with nutritional value for Biting village 58.91 while the average nutritional status of children is a good nutritional value 57.81. Keyword : Anthropometry index, Fuzzy Logic, Nutritional status. Digital Repository Universitas Jember


Purpose:Acute myeloid leukemia (AML), is a heterogeneous clonal disorder of hematopoietic progenitor cells. Acute promyelocytic leukemia (APL), is a subtype of AML and characterized by aberrant morphology of promyelocytes. The most specific chromosomal disorder that occurs in APL patients is (15;17) translocation. This translocation the promyelocytic leukemia (PML) gene on chromosome 15 and the retinoic acid receptor (RAR) alpha gene on chromosome 17 fuse and produce a PML-RARα fusion protein. Bendamustine is a water soluble, white, microcrystalline powder with amphoteric properties due to a nitrogen mustard group and a butyric acid side chain. Bendamustine acts as an alkylating agent and also has purine analog activity. Bendamustine has more moderate toxicity profile than the other alkylatingg agents. In our study, it is aimed to investigate cytotoxic, cytostatic and apoptotic effects of bendamustine on APL cell line HL60. Also we aime to evaluate the effect of bendamustine on HL60 cells according to the expression of genes including several signal transduction pathways such as; cell cycle, mitotic catastrophe and apoptosis, Materials and methods: Cytotoxic effect of bendamustine on HL60 cell line was assessed by WST-1 assay, apoptotic effect by Annexin V and Apodirect Tunnel assay and cytostatic effect by Cycletest Plus DNA Reagent Kit. Also the effect of bendamustine on expression levels of several cell cycle, mitotic catastrophe and apoptosis related genes in HL60 was determined by quantitative RT-PCR relatively. Research Article Gönderilme tarihi: 18.04.2018 Kabul tarihi: 08.08.2018 Sezgi Kıpçak, Doktora Öğrencisi Ege Üniversitesi Tıp Fakültesi Tıbbi Biyoloji Anabilimdalı, İZMİR, e-posta: firstname.lastname@example.com (orcid. org/0000-0003-0615-3844) Nur Selvi Günel, Dr.Öğr.Üyesi, Ege Üniversitesi Tıp Fakültesi Tıbbi Biyoloji Anabilimdalı Bornova/İZMİR, e-posta: firstname.lastname@example.com (orcid. org/0000-0003-0612-2263) (Sorumlu yazar)


A method for selecting wells and coal seams to be stimulated is suggested by according to the geology and reservoir characteristics of Xinji Area. It is convinced of sure that 2% KCl water and Lanzhou sands should be the first selections used hydraulic fracture fluid and proppant in Xinji Area by having down eight treatments for eight coal seams of the three pilot wells. On the base of utilization of advanced software doing design before treatment,real-time analysis during treatment and simulation after treatment, the highest gas production rate is as high as 3 278 m3/d by good planning and prompt operating for fracture jobs. All of the results will provide a basic technology for coalbed methane development in future in this area.


The present paper aims to analyze and understand, from an intersectional point of view, the extent and the characteristics of racism in football in Portugal, based on the perspectives of football fans, coaches, amateur players, professional players, journalists, parents, and other elements directly or indirectly involved in the modality. Using an online questionnaire, this exploratory study involved 1681 participants, 456 self-identified as women, 1221 as men, and 4 as non-binary, aged between 13 and 61 years old (M = 33.02; DP = 12.64). The results show gender, skin color, ethnicity, sexual orientation/gender identity, and functional diversity are the main factors explaining discrimination in football, with differences between genders. Nearly 70% of women and 50% of men admitted the existence of racism in football in Portugal. In addition, associations between participants' condition, age, perceptions, and experiences of racism were found, with amateur players and younger participants revealing a stronger position concerning the topic. This study can inform contemporary debates in critical research, particularly around football, discrimination, and cultural citizenship. Intersectional research across football studies is crucial to better understand the racialized aspects of football and develop better policies that can prevent and combat racism.


Locus of control (LOC) has been implicated in predicting mental wellbeing outcomes in a variety of theories and empirical studies, however the mediating mechanisms between the trait and mental wellbeing are not well known. The King and Rothstein (2010) model of resiliency posits self-regulation as the active mechanism that leads to recovery in resiliency related outcomes following significant adversity. This study investigated the mediating role of affective, behavioral, and cognitive self-regulation between locus of control, depression, and anxiety using mediation analysis. The results showed LOC significantly predicted all three self-regulation components, as well both depression and anxiety. behavioral and cognitive self-regulation were found to significantly predict depression and anxiety, suggesting partial mediation for both, but not affective regulation. Results and implications for the resiliency process are then discussed, including the role of self-regulation in recovering from adversity.


Background: Liquid biopsy has been established as a powerful, non-invasive means to profile tumors in and identify clinically relevant variants. However, the presence of clonal hematopoiesis (CH) variants, or biological noise, due to aging or therapy has potential to confound biomarker interpretation. Currently, comprehensive methods to filter out non-tumor variants require genotyping the white blood cell (WBC) fraction of the paired plasma sample, which is a costly, complicated workflow. A plasma-only, bioinformatics solution to identify non-tumor variants is needed for accurate biomarker assessments in the cell-free DNA (cfDNA).
 Method: An ensemble model was trained on a database of >250,000 plasma samples comprising healthy donor, early and late-stage cancer patients sequenced on the Guardant360TM , GuardantREVEALTM, and GuardantOMNITM liquid biopsy panels as well as public tissue datasets. The model was optimized with 5 fold cross-validation and hyperparameter tuning to produce a non-tumor and tumor variant classifier. To validate these calls, 116 paired plasma and WBC advanced cancer samples were selected for high prevalence of putative CH variants and genotyped using an in-house bioinformatics pipeline. In the validation cohort, cfDNA variants were determined to be of non-tumor or CH origin if there was molecule support in the WBC; cfDNA variants above 0.6% (limit of detection in the gDNA) with no support in the WBC were determined to be from the tumor.
 Results: The validation cohort consisted of 2150 somatic SNV and Indels, 956 of which were confirmed in the WBC and 1194 confirmed as plasma-only. Half of confirmed CH variants (48%, 458/956) occurred in known CH genes, while the other half occurred in genes such as TP53, ATM, NOTCH4, FAT1, SRSF2. No clinically actionable variants were confirmed in the WBC. Non-tumor or CH predictions were made for 624 somatic variants: 515/624 correctly identified CH, for a positive predictive value (PPV) of 83%. Of all CH variants confirmed in the WBC, 54% (553/956) had a CH or non-CH prediction; CH predictions had 91% (515/553) positive percent agreement (PPA) with the WBC. Remaining variants with no CH prediction (403/956) were low or no prevalence across datasets and occurred predominantly in LRP1B, TET2, TP53, KMT2D. Nearly half (67%, n=109) of CH predictions not in WBC occurred in a CH gene. For non-CH gene variants, 16% of false positive predictions occurred in 6 variants across 4 genes (ACVR2A, RNF43, B2M, FLT3).
 Conclusion: We present a plasma-only method that has high PPA and PPV with WBC genotyping for classifying non-tumor, CH variants in the cfDNA. Further investigation is underway to improve the sensitivity of annotating rare CH variants. Accurate CH identification is critical for treatment selection across targeted therapies, particularly for loss of function variants in DNA repair genes that may confer sensitivity to PARPi or ATRi therapies.
 Citation Format: Jennifer Yen, Yu Fu, Jeff Werbin, Katie Quinn, Robert Foley, Minh Trahn, Carin Espenschied, Scott Higdon, Brett Kennedy, Han-Yu Chuang. Validation of a bioinformatic model for classifying non-tumor variants in a cell-free DNA liquid biopsy assay [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 3135.


In this paper,Nanjing Gulou district Dafangxiang senior home care service center,established as a result of the public-private cooperation which includes government,business enterprises and education institutions,is studied as a model to discuss the constructive interaction mechanisms among the government,education institutions,and non-profit organizations as well as the important roles they play in the promotion of the professional development of senior home care services in China.


Transatlantic defense cooperation is a little like the weather: everybody talks about it, but nothing much seems to happen. Meanwhile, Europe is building a separate "European" defense industry, based in part on shortsighted, if not downright misguided, calculations of self-interest. For its part, the United States is tentative at best and ambivalent at worst about greater cooperation. But as the United States and Europe dither, the effectiveness of the nato alliance?and ultimately its future?is increasingly at risk. The costs of inaction mount daily. Declining defense budgets, already stretched too thin, are denied the efficiencies that greater transatlantic cooperation could yield. Both Europe and the United States have therefore had to delay the modernization of their mili tary forces and thus have been slow to take advantage of advances in technology?notably information technology that applies to command, control, communication, and intelligence. The air war in Kosovo


ABSTRACT This paper explores the alarming phenomenon of violent extremism in university campuses. It probes why education fails to prevent violent extremism in this case? Drawing on Robert Cox's distinction of problem solving and critical theories, the paper examines policy discourses that aim to prevent violent extremism through education. It is observed that dominant policy discourses take up problem solving approaches to prevent/counter violent extremism and fail to take into account the broader structural violence that feeds extremist ideologies. The counter violent extremism policies largely view education as a means to control thinking rather than develop it. Such policies hinder the development of critical consciousness in students that can provide effective defence against extremism. Hence, there is a need to rethink education to counter extremism. Subsequently, the paper shifts its focus to Pakistan, where education has remained a central concern of counter extremism policies since 9/11. Based on 13 expert interviews, I explore higher education practices in Pakistan from practitioners' perspective. The practitioners point out multiple problems of educational status quo that need to be addressed to counter extremism on campus effectively.


Metal Matrix Composites (MMCs) are currently being investigated because of their superior properties as compared to those of most conventional materials. Two types of reinforcement (alumina and silicon carbide) have been extensively investigated by the scientific community. The introduction of new reinforcements such as intermetallics to aluminium alloys continues to be investigated in order to improve final behavior of AMCs as well as to avoid some drawbacks of using ceramics as aluminium alloys reinforcements. At present, the two major obstacles to the application of such materials are high cost and chemical reaction at reinforcement/matrix interfaces during materials processing and service at elevated temperatures [1, 2]. The synthesis of materials by high energy ball milling of powders however was developed to produce fine and uniform dispersions of oxide particles in nickel base superalloys presently is being used to produce numerous materials including metal matrix composites [3, 4]. The mechanical alloying process changes dramatically the powder characteristics, the more refined microstructure improved dispersion of the reinforcement particles and improved mechanical properties can be achieved with this process route compared with the same composite produced by conventional PM process and hot extrusions.


ACKNOWLEDGMENTS I thank my adviser, Professor Gul Agha, and the members of the Open Systems Laboratory for supporting my work with their time, resources and ideas. The study described in this thesis is a continuation of a project done in collaboration with Together we built all the infrastructure used in developing this thesis, I have made only relatively small improvements. Since the original project ended several conversations with Amr and Predrag Tosic have been fruitful. Myeong-Wuk Jang generously found time for me to run my own experiments when his computers were idle. I also acknowledge the unceasing moral and grammatical support of Stephanie Jensen.


Gap junction(GJ)is intercellular channel,which is a cental empty channel made of of many connectin subtype,which results in cytolymph communication among cells and plays an important role in maintaining cell normal function as well as the genesis and development of epilepsy.Different tissues express different connectin.Gene knockout of connectin subtype can affect convulsion attack in animal model with epilapsy.Blocker of gap junction has anti-convulsion effect.The effect of gap junction in pathogenesis of epilepsy needs further studying.Specific inhibitor of gap junction will be a new method in treating epilepsy and provide a new ideas for epilepsy therapy.


Red dragon fruit ( Hylocereus lemairei Hook.) contains Phyto albumin and antioxidant compounds such as phenolic compounds and vitamin C. Corn contains vitamins A, B, and E as antioxidants


In this study the effects of 24 D on the adsorption and release of Cu(Ⅱ)on montmorillonite have been investigated.The results show that Cu 2+ adsorption in the presence of 24 D on montmorillonite is lower than in the absence of 24 D.When the clay was previously treated with 24 D,the Cu(Ⅱ)adsorption is better than when both the adsorbates are added simultaneously showing that there exists a competition between Cu and 24 D.In all cases the adsorption processes obey both Langmuir and Freundlich isotherm models.In the simultaneous adsorption,the percentage of Cu desorbed is highest and can reach 30%.However,the percentage of Cu desorbed in the absence of 24 D is lowest,indicating that the Cu adsorption without 24 D seems virtually nonreversible.


Legal theory has the important position in the whole science of law,and the teaching of jurisprudence is difficult but of greater significance.The teaching should be carried out despite difficulties to grasp the four general aspects in legal theory education: the reading,the thinking;the practice;and the language,to improve the legal theoretical attainment in the students.


IntroductionActing as the host country for the Olympic Games constitutes a unique opportunity for a nation to engage in intense debate about the particular images of nationalism and national identity that are presented to an extremely large, global audience. Chen (2010), for example, argues that a country's success as an Olympic host depends upon its ability to manage the media narratives in such a way as to "culturally seduce all the world" (814); similarly, Liang (2010) points out that national broadcasters use these highly ritualized media events in order to imagine a shared national identity that often undermines the supposed Olympic ideals of internationalism (820). Heinz Housel (2007) specifically considers how the Opening Ceremonies of the Sydney 2000 Summer Games, as presented in Australian media sources, construct an image of a multicultural community that, through linear historical progress, has become unified under the umbrella of the Australian nation (446). In a context in which language and languages represent an important aspect of national identity, these elements may take on additional significance for the identities being constructed and presented in these mediated events. DiGiacomo (1999) highlights the way that the 1992 Barcelona Olympics, held in the capital of the Catalan region of Spain, brought new international attention to the significance of language choice for both Catalan and Castillan identities. The actors involved in constructing these images include the state itself, the organizing committee and, importantly, media broadcasters, who possess a great deal of creative control over the form and content of the stories they tell and re-tell over the course of the Games.During the Vancouver 2010 Winter Games, the organizers and media repeatedly focused on multiculturalism and the role of Canadian Aboriginal peoples in shaping Canadian national identity, especially during the Games' Opening Ceremonies. The latter aspect was also highlighted in the emphasis that was placed on the involvement of the "Four Host First Nations" on whose traditional lands the Games were held, in the planning process. In addition, the perception that the French language was not granted enough presence during the Opening Ceremonies sparked a heated public debate about the importance of official bilingualism to Canadian identity. Although languages other than English and French were rarely discussed, an additional language ideological debate (Blommaert 1999) concerning Canadian Indigenous languages also took place during the Vancouver Games. This debate reveals the ways in which the same event can be used to support different kinds of identity claims for different participants in the discussion. Constructions of both Canadian identity and Aboriginal identity are at work in this story, particularly ideals of multiculturalism and inclusion for the former, and the importance of language revitalization for the latter.The Rogers/CTV broadcasting consortium that won the Canadian rights to televise the Vancouver 2010 Olympic Games decided to use affiliated networks in order to include coverage of Olympic events in 22 different languages, including eight Aboriginal languages.1 Originally, the media corporations brought forward a proposal to the International Olympic Committee (IOC) that only featured "ethnic telecasts on OMNI" (Houston 2009) and limited the involvement of the Aboriginal People's Television Network (APTN) to the Opening and Closing ceremonies. After the IOC awarded the rights to this group, however, APTN pushed for greater participation. The result was the first-ever inclusion of an Aboriginal television network as an official broadcaster in this kind of worldwide sporting event. APTN aired daily coverage in English and French across the country, and coverage of specific events in different Aboriginal languages on three regional feeds (North, East and West).2 While the promotion of endangered languages constitutes a component of APTN's mandate, and regular programming includes a significant amount of Indigenous language content, the size and nature of this event make the decision and its impact much more complex. …


. A special case of destructibility for Blaschke products is introduced and studied. An example is given of a destructible Blaschke product which becomes indestructible when a single point is deleted from its zero-set.


The academic entrepreneurial processes attracted significant interest from policy makers and researchers alike. Extensive research tried to shed light among others on the factors that enhance academic entrepreneurship, the organizational consequences of those, respectively on the potential concerns that are related to them. Interestingly it seems that somewhat less attention has been given to one of the key actors in the entrepreneurial turn, to the scientists themselves. This chapter aims to provide an insight into the world of academic entrepreneurs by introducing their importance in the entrepreneurial processes, the motivations of scientist for entrepreneurship, respectively shedding light on their diverse involvement by differentiating between commercialization in engaged universities and commodification in entrepreneurial universities. Through some examples of the categorization of academic entrepreneurial types it also highlights the complexity of the phenomenon.


For solving the difficult problems of quantitative description on migration complexity and spatial inhomogeneity of seasonal frozen soil moisture during frozen-thaw process,soil moisture profile of different stages in seasonal frozen soil region was taken as the research object and geostatistics was performed to study its spatial variability.The results indicated that soil profile moisture of different stages had good spatial structure and strong spatial correlation.Seasonal frozen-thaw process weakened the spatial correlation of soil profile moisture and had intense spatial redistribution effects on it.The application of geostatistics can provide a new thought and method for the research on soil moisture migration mechanism during frozen-thaw process in seasonal frozen soil region.


The contribution of high-eccentricity trans-Neptunian objects to the observed populations of both short-period and long-period comets is estimated. About $10^{10}$ objects with a radius $R>0.7$ km in orbits with perihelion distances $28<q<35.5$ AU and semimajor axes $60<a<1000$ AU are the main source of Jupiter-family comets. If the population of high-eccentricity trans-Neptunian objects formed about 4.5 Gyr ago, the mean near-parabolic flux produced by these objects is on the order of 0.3-1.0 AU$^{-1}$ yr$^{-1}$ for comets with $R>0.7$ km.To search for other articles by the author(s) go to: http://adsabs.harvard.edu/abstract_service.html


This chapter briefly examines the impact of prevailing technological trends on student learning and considers the potential role of e-learning technology in establishing learning environments favourable to higher education. The author identifies the noticeable decline in student competence, language/communication skill, and research ability as an outcome of emerging social media trend. Research indicates that current trends may pose a challenge to academia in the long run. The concluding strategies are suggested for establishing e-learning environments that facilitate improvement in student ability within higher education: 1) incorporating student-centric approach within higher institutions, 2) encouraging culture change among lecturers to create a more e-learning environment, 3) student goal-setting approach in e-learning design, 4) adopting online student portfolios for feedback, 5) implementing a learning strategy using digital media to enforce a learning culture.


The use of response cost as a means of modifying behavior has been well documented ( 2 1 , primarily to change individual behavior; however, it may also be applied to group's behavior ( 1 , 3 ) . The current study was designed to increase the rate of basket retrieval by patrons of a public swimming pool. Patrons rarely returned the baskets used for storing personal irems to the pool lobby for reuse so staff were forced to take time from their duties to recrieve the baskets. Six weeks of baseline data indicated thar the average weekly percentage of baskets returned to the pool lobby was 2.5, a low level of the target behavior. An aversive response cost was selected as the contingency because the clientele of the pool were primarily repeating customers, and many were obviously consistently nonresponsible for baskets. All empty baskets not remrned to the pool lobby were confiscated for 1 wk. When patrons were informed over 6 wk.. the average percentage of baskets returned weekly rose to 75.5. Remrn to the baseline conditions for 6 wk. decreased the weekly average to 14.3% returned baskets. While the reduction was dramatic, the target behavior did not drop to the initial low level. Reestablishment of the contingency for another 6 wk. increased the number of baskets returned weekly to the pool lobby co an average of 90.2%. These data indicate that the response-cost technique as employed in this study was a viable means of ensuring the return of storage baskets to the swimming pool lobby. Although the patrons initially complained about the procedure, most of those questioned conceded the consequences were appropriate and enhanced the operation of the pool. The staff were satisfied with the outcome as it allonred more of their time and attention to be focused o n their primary duties.


In this work, calculation the characteristics of dusty plasma exist in the space for different regions interstellar cloud, interplanetary space, Halley comet, Saturn rings (E and F), interstellar plasma ,solar wind and solar corona. It noticed the characteristic of dusty plasma different from one region to another region in the space. It shows the density of electrons is lower in interstellar cloud, interplanetary space and Saturn rings (F and E).High density of electrons in solar corona, solar wind and interstellar plasma. The temperature of electrons in the space is high in solar corona and Saturn rings (F and E).It noticed when electrons density increases due to plasma frequency for electron and ion, and coupling parameter of plasma increases too. It noted electrons temperature is increases led to the Debye length, Debye sphere, and electron velocity increases too.Another process is versa verse. According to the different in the electrons density and temperature in the space causes at different characteristics of dusty plasma exists in the different region in the space.


This work reports on the design of CMOS-integrated sensors for radiation detection, incorporating an avalanche multiplication layer to amplify the signal generated by the incidence of a charged particle. The avalanche gain, obtained with a dedicated implantation, is used to enhance the Signal-to-Noise Ratio of the sensor signal, and thus to increase its charge and timing resolution. The proposed devices are obtained with the modification of a 110nm CMOS process customized for the production of Fully Depleted Monolithic Active Pixel Sensors, and are suitable for the fabrication of pixelated large-area Time-Of-Flight detectors.


Abstract This paper seeks to illuminate teachers' perceptions of the challenges and benefits of systematically examining students' thinking as part of a professional development program in elementary mathematics education. Using a framework of models of conceptual change and principles of discomfort, three elementary teachers' perceptions of their experiences with reform-oriented mathematics instruction and systematically examining students' thinking were analyzed. Analysis of interview data yielded five organizing themes. Findings offer insight into understanding the efficacy of examining students' thinking as a professional development strategy.


Evaluation of progeny resulting from controlled crosses and selfs of various plum (Prunus salicina and hybrids) cultivars revealed that resistance to black knot Apisporina morbosa (Schw.) is controlled by a single recessive gene (proposed designation bk) in the resistant cultivars studied. `Bruce', `Munson', `Crimson', and `Ozark Premier' were homozygous resistant (bkbk), while `Methley' was susceptible and heterozygous (Bkbk) for the trait.


The accounting education, from the South and for the South, demands that teachers and students get over the institutional barriers. To this end, this article suggests the need to strength the individuality and to teach the accounting as know-how providing the solution for multiple problems the society is facing. A reflection about three key aspects is made in order to plan our public accounting programs on behalf of an integral education: Consistency, accounting, and environment, accounting ethics, foundations, and guarantees that rule the offer and evaluation of the study program. Finally, positioning the accounting education with the recognition of the subject and the individuality that emerges today is proposed; and the achievements of the Colombian accounting education are underlined, especially from the 80's. There just remains rethink what we understand as evolution and development of education and accounting research in the South, at Latin-America.


Pageantry, spectacle, and visual display have dominated nearly every stage production of Henry V. Though there have been occasional attempts to keep the play to a more standard theatrical simplicity-symbolism, or Elizabethan "purity"-for the most part these approaches have met with disapproval from both critics and audiences. William Poel's austere and Elizabethan production with Ben Greet's company, for instance, hadan unfavorable reception in 1901. While we may reason that this is because Poel's audiences were used to the wildly showy stage machinery of the late nineteenth century, later audiences displayed a similar taste for spectacular Henrys. However innovative, the stripped-down productions of the nineteen-twenties and thirties yielded to spectacle in the nineteen-forties, and visual splendor has characterized the play ever since. Even in the seeming exception-the Royal Shakespeare Company's 1975 Henry V directed by Terry Hands-spectacle, or its suppression, remained paramount. Both British and American critics praised designer Farrah's imaginative use of a canopy (which could stand for either royal courts or battlefields), and censured the bare stage and sparse costumes in its opening scene: calling the beginning "drab" and "discouraging,"1 they warmed to the show only later when costumes, scenery, and pomp entered. (See Figs. 1 and 2.) Interviews with the director and actors from the RSC in Sally Beauman's acting edition (Pergamon, 1976) suggest that it is patriotism, not the text of the play, that insists upon spectacle. And she points out that not only has the play usually been performed as a stage pageant, but that since Laurence Olivier's 1944 wartime film it is his particular kind of pageantry against which subsequent productions are judged.2 In part, this may be because Olivier's single-mindedly courageous Henry is in keeping with past interpretations. As A. C. Sprague tells us in Shakespeare's Histories, Henry has been generally interpreted and presented as practical, just, dignified, and, also, unintellectual and unsubtle.3 Just as important was Olivier's extension of the play's possibilities for spectacle: it could give full play to the physical and visual qualities inherent in the text. So many critics and scholars-Mark Van Doren, Allardyce Nicoli, and J. Dover Wilson to name just a few-have commented on the restrictions of the "wooden O," that Shakespeare apologizes for, that it is hardly necessary to belabor that point (Wilson finds Shakespeare complaining of the inadequacy of the dramatic form twenty-five times).4 Popular criticism heralding the 1944 film predictably enough declared that Shakespeare could be said to have "written for the movies" and that he would have made a great film director. Laurence Olivier's program notes to the film even declare that Shakespeare's splitting up of the action into a multitude of small scenes is "almost an anticipation of film technique."5 But such hopeful anachronisms need not be invoked to see the extraordinary visual interpretation that Henry V offers, even demands. Tableaux, trumpets, angels, even moving dioramas in the nineteenth-century productions of Macready, Charles Kean, and Charles Calvert were enthusiastically received (notable exceptions being Henry James's wry comments on such "scenic splendours").8 Soldiers painted on backdrops by Mansfield swelled the ranks for the battle of Agincourt, and even as recently as 1956 the Stratford Ontario Festival Company had an open stage production with elaborate structures, stairs, and ladders. To this tradition belong some of Olivier's devices: music, pageantry, rich medieval costumes, even the coronation and white horsesince 1761 an elaborate Coronation has been standard: Henry's white horse a staple since the Calvert production. With an ingenious twist on the notion of "period," the background for some of the scenes was proudly derived from calendar pictures in Les Tres Riches Heures du Duc de Berry. …


Forms, meanings, dialects, and characteristics of Sasak language Pronouns were
discussed by Nurhadi
This ethnographical research gathered the information from the informants in a Bayan
community in North Lombok, west Nusa Tenggara, Indonesia. The informants were selected in
terms of their age, mobile and their speaking Indonesia ability. The language practices were
observed and the informants were in-depth interviewed. Personal pronoun sentences were
analysedby employing a referential identity method with deviding-key-factors techniques.
Bayan people communicate pronouns in two directions: from low-to-high pronouns
and high-to-low pronouns. low-to-high pronouns refers raden-to-menak and menak-to-jajar
karang. high-to-low pronouns refers to jajar karang-to-menak and raden, menak-to-raden.
Amonst the levels, they may speak pronouns variously, considering ages, position, and status.
The personal pronouns they seem to apply are aku, tiang and dawek diq, kamu, epe, sida,
pelinggih, and pelungguh. Social relation, and gender so far do not indicate an effect on
applying personal pronouns.


Based on permanent income theory,from the perspective of demand,this paper constructed a theoretical model which included main explanations on China international trade surplus.And the explanations are exchange rate,insufficient consumption,resource and invest-saving gap.The model pointed out that insufficiency of expected income is the origin of trade surplus.The influence of exchange rate on trade surplus was uncertain.Insufficiency of investing chance and defect of financial system expanded the trade surplus.At the end,this paper pointed out four suggestions which were improving social security system,developing legal institutions,curbing inflation,and keeping exchange rate smooth and steady.


Activation of the complement system can induce and enhance inflammatory reaction. Mannose-binding lectin-associated serine protease-1 (MASP-1) is an abundant protease of the complement lectin pathway; however, its physiological function is unclear. In this study, we demonstrate for the first time that MASP-1 is able to activate Ca2+ signaling, NF-κB, and p38 MAPK pathways in cultured HUVECs. Activation was initiated by MASP-1 only; the related protease, MASP-2, had no such effect. The phenomenon was dependent on the proteolytic activity of MASP-1, suggesting modulation of endothelial cell function through a protease-activated receptor (PAR). Using synthetic peptide substrates representing the protease-sensitive regions of PARs, we were able to demonstrate that PAR4 is a target of MASP-1. The presence of functionally active PAR4 in HUVECs was demonstrated using PAR4 agonist peptide and mRNA quantification. Finally, we showed that the amount of membrane-bound intact PAR4 decreases after MASP-1 treatment. All of these results provide a novel link between the regulation of endothelial cell function and complement system activation, and they suggest that MASP-1-induced PAR4 activation could contribute to the development of the inflammatory reaction.


Biofloc-Aquaculture System is considered as an effective measure to the intensive aquaculture industry facing natural resourse and environmental constraints,which could increase dietary protein retention ratio and improve the capacity of water quality control.This paper analyzes the differences of carbon addition between biofloc technology(BFT) and traditional technology in shrimp farming,advantages of lower feed costs,lower water treatment costs and disease control,the limitation of large consumption of carbon resourse and power in BFT sharmp farming,and looks forward to the BFT applied to shrimp culture in China associated with the techniques of Litopenaeus vannamei farming in biofloc ponds.


The aim of this study was to assess the number of fever episodes as a risk factor for febrile seizure recurrence during the first 6 months after the last previous febrile seizure. In a 6‐month follow‐up study of 155 children, aged 3 months to 5 y, with a first or a recurrent febrile seizure, the occurrence of fever episodes and febrile seizure recurrences was prospectively documented. Using logistic regression analysis the association between the baseline characteristics and the number of fever episodes and the outcome, a febrile seizure recurrence, was studied. In total, 260 fever episodes were registered; 29 children experienced 1 or more febrile seizure recurrence during follow‐up. Two factors were associated with febrile seizure recurrence: the number of fever episodes [odds ratio (OR) =1.8; 95% confidence interval (CI): 1.4‐2.4)] and age at study entry (OR = 0.6; 95% CI: 0.3‐1.1). In a multivariable model, only the number of fever episodes remained significant. In conclusion, the number of fever episodes increases the risk of a febrile seizure recurrence with a factor of 1.8 per fever episode in the first 6 months after a febrile seizure.