Background and Objectives: Ambivalence over emotional expression plays an important role in quality of life and adherence to treatment in cancer patients. The aim of this study was to determine the mediating role of depression and social support in the relationship between ambivalence and quality of life and adherence to treatment in cancer patients. Materials and Methods: The present study was descriptive and based on structural equation modeling. For this purpose, 206 cancer patients referred to Dezful medical centers in 2020 were selected by convenience sampling method and completed questionnaires of ambivalence over emotional expression, quality of life, adherence to treatment, depression, and social support. Data were analyzed using statistical methods of structural equation modeling and Pearson's correlation. Results: The results showed that there was a negative and significant relationship between ambivalence and quality of life (β=-0.183), depression and adherence (β=-0.178) (p<0.05), ambivalence and social support (β=-0.411), between depression and quality of life (β=-0.288) (p<0.01) and a positive and significant relationship between ambivalence and depression (β=0.441), social support and quality of life (β=0.221), social support and adherence to treatment (β=0.249) (p<0.01). The mediating role of depression and social support variables was confirmed. Conclusion: Considering the mediating role of depression and social support in the relationship between ambivalence and quality of life and adherence to treatment, it is recommended in psychological therapies, in the first place, the variable of ambivalence to be examined and evaluated and the important role of mediating variables to be considered.


Includes 2 articles one taken from the newspaper "The Times" of 23 of October 1980 which is discussing the production "The Leaping Match" and the other taken from the newspaper "L-Orizzont" of 23 of October 1980 which is discussing the production produced by L.Y.T. "Il-Lobgha tal-Quiz".


Abstract The Murchison Widefield Array is a Square Kilometre Array Precursor. The telescope is located at the Murchison Radio–astronomy Observatory in Western Australia. The MWA consists of 4 096 dipoles arranged into 128 dual polarisation aperture arrays forming a connected element interferometer that cross-correlates signals from all 256 inputs. A hybrid approach to the correlation task is employed, with some processing stages being performed by bespoke hardware, based on Field Programmable Gate Arrays, and others by Graphics Processing Units housed in general purpose rack mounted servers. The correlation capability required is approximately 8 tera floating point operations per second. The MWA has commenced operations and the correlator is generating 8.3 TB day−1 of correlation products, that are subsequently transferred 700 km from the MRO to Perth (WA) in real-time for storage and offline processing. In this paper, we outline the correlator design, signal path, and processing elements and present the data format for the internal and external interfaces.


Field experiments were conducted to study the performance of watermelon (Citrullus lanatus) under both open field and polyhouse condition at the Division of Horticulture, UAS, Bangalore. The experiment was laid out in Factorial randomized complete block design with two main and sub treatments with five replications. The results revealed that the plants grown under polyhouse recorded significantly higher TSS of pulp (10.67°Brix), total sugars (5.10%), reducing sugar (1.72%), non reducing sugar (3.38%), sugar to acid ratio (14.57) and organoleptic evaluation of the fruit (4.46) whereas, less titratable acidity (0.35%) was noticed under open field condition. From this investigation, it can be concluded that cultivation under polyhouse leads to improvement in the fruit quality characters.


An 80 year old woman who rarely attends your surgery presents with a two month history of difficulty getting her shoes on due to swollen feet and breathlessness going upstairs.

### Ask about

### Clinical examination


A comparison of scores on the Allport-Vernon-Lindzey Study of Values was made for 130 mathematically-gifted adolescents (WAIS Verbal IQ = 138 ± 8.3, Performance IQ = 125 ± 10.7) and the normative medical school freshmen. The former group are more concerned with theoretical values than with religious and social values.


In this paper, we derive a new basis for constructing C2 quintic interpolation spline curve that is called BB spline. The C2 biquintic interpolation spline surface is briefly constructed by tension-product and has properties of interpolation, C2-continuity and locality. The local shape of interpolation spline curve and surface can be modified by the change of shape-parameters. The effects of the shape-parameters are also discussed.


Under the influence of an external electro-magnetic (EM) field, metallic nanoparticles (NPs) can exhibit a resonant oscillation of their free-electron gas, known as Localized Surface Plasmon Resonance (LSPR). In correspondence of the LSPR, the electrical polarizability of the NPs becomes resonantly large, leading to the significant enhancement of the EM fields in the near proximity of the NPs and to an enhanced absorption of the EM energy. The coupling of a plasmonic material to a magnetic counterpart has the potential to induce a variety of extremely interesting and useful effects. So-called magneto-plasmonic materials, in which a magnetic substance acts as a plasmonic resonator or is optically coupled to a plasmonic material, exhibit indeed strongly intertwinned magnetic and optical response. The magneto-optical response of the magnetic counterpart can be influenced and enhanced at the LSPR frequency via the incident EM field. A straightforward way to obtain such kind of systems is combining a noble metal with a magnetic metal, the first one characterized by its intense surface plasmon resonances (SPR) and the second one by a strong MO response. In this work, we compare the MO response of 2-dimensional layers of magnetite nanocrystals (NC) optically coupled with plasmonic substrates composed of ordered arrays of either Au or Ag nanoparticles. While the magnetic NCs employed were kept identical, the LSPR wavelength of the Au and Ag NP arrays were superimposed or detuned with respect to the dominant magneto-optical transitions of magnetite, respectively. In the off-resonant case, the MO response of the NC appears decoupled with respect to the plasmonic response, while a significant enhancement of the MO signal is observed in the resonant case. In both cases, we observed that the contribution to the MO signal arising from the magnetic and the plasmonic counterparts can be clearly separated, even under optical coupling conditions, based on their markedly different magnetic-field dependence.


Understanding the relationship between politics and administration is critical for the field of public administration. This understanding has been obscured, however, by inappropriate emphasis on dichotomy as a central organizing concept. Although it is typically rejected as a normative and empirical guide, Patrick Overeem has attempted to restore the concept by reducing its scope to the mutual non-interference in the selection of counterpart officials and the exclusion of administrators from resolving political controversies. This is important, but it is one of five elements that shape a model of political-administrative relations along with political neutrality, professionalism, sharing and division of functions, and distinctive means. A model of complementarity better captures the complexity of a relationship that includes both distinction and overlap. The term dichotomy is better reserved for situations in which there is strict separation of roles and limited interaction. Although such conditions are rare, they are approximated in the relationship when services are performed under contract.


FIELD: mobile communications. SUBSTANCE: channel of relative data rate allocation is transmitted from base station to mobile station that includes command to control data rate in the uplink, and the mobile station determines that the relative data rate allocation channel including the Keep command to instruct data rate keeping is received in the mobile station when there is no data in the transmission buffer intended for transmission, and signal of receiving in the channel of relative data rate allocation is defined as "0" or "+1", and the data rate is kept. EFFECT: provision of data transmission without lowering of data rate in the uplink, even if new data appears for transmission in the transmission buffer. 3 cl, 14 dwg


This research work focuses on the performance optimization of composites containing both micron and nano size TiO2 particles separately in various concentrations and to understand the role of each on the thermal stability and moduli of the composites. Thermal stability of the particle-reinforced composites increased on increasing the concentration of TiO2, both in nano and micron filled cases, except for the 2.5 wt% nano-filled composite. Storage modulus (E') increased on adding micron-TiO2 to the epoxy hardener resin system from 1 - 2.5 - 5 wt% respectively and decreased dramatically on further increasing the micron TiO2 content to 7.5 and 10 wt% respectively. Nano TiO2 particle-reinforced composites showed an increasing trend of storage modulus for 2.5 - 5 - 7.5 wt% TiO2 filled composites with respect to the neat resin system. Presence of both micron and nano TiO2 particles increased the Tg of the composites. Also, the effect of sonication on the modulus and Tg is discussed. As a whole, composites in which the TiO2 particles were dispersed through the resin matrix by glass rod revealed better results (higher storage moduli and Tg) than those mixed by sonication, due to high viscosity of the epoxy resin used.


Efficacy of Levetiracetam, Fosphenytoin, and Valproate for Established Status Epilepticus by Age Group (ESETT): A Double-Blind, Responsive-Adaptive, Randomised Controlled Trial. Chamberlain JM, Kapur J, Shinnar S, Elm J, Holsti M, Babcock L, Rogers A, Barsan W, Cloyd J, Lowenstein D, Bleck TP, Conwit R, Meinzer C, Cock H, Fountain NB, Underwood E, Connor JT, and Silbergleit R, Neurological Emergencies Treatment Trials; Pediatric Emergency Care Applied Research Network investigators. Lancet. 2020;395(10231):1217-1224. doi:https://europepmc.org/article/med/32203691 Background: Benzodiazepine-refractory, or established, status epilepticus is thought to be of similar pathophysiology in children and adults, but differences in underlying etiology and pharmacodynamics might differentially affect response to therapy. In the Established Status Epilepticus Treatment Trial (ESETT), we compared the efficacy and safety of levetiracetam, fosphenytoin, and valproate in established status epilepticus, and here, we describe our results after extending enrolment in children to compare outcomes in 3 age groups. Methods: In this multicenter, double-blind, response-adaptive, randomized controlled trial, we recruited patients from 58 hospital emergency departments across the United States. Patients were eligible for inclusion if they were aged 2 years or older, had been treated for a generalized convulsive seizure of longer than 5 min duration with adequate doses of benzodiazepines, and continued to have persistent or recurrent convulsions in the emergency department for at least 5 min and no more than 30 minutes after the last dose of benzodiazepine. Patients were randomly assigned in a response-adaptive manner, using Bayesian methods, and stratified by age-group (<18 years, 18-65 years, and >65 years), to levetiracetam, fosphenytoin, or valproate. All patients, investigators, study staff, and pharmacists were masked to treatment allocation. The primary outcome was absence of clinically apparent seizures with improved consciousness and without additional anti-seizure medication at 1 hour from start of drug infusion. The primary safety outcome was life-threatening hypotension or cardiac arrhythmia. The efficacy and safety outcomes were analyzed by intention to treat. This study is registered in ClinicalTrials.gov, NCT01960075. Findings: Between November 3, 2015, and December 29, 2018, we enrolled 478 patients and 462 unique patients were included: 225 children (aged <18 years), 186 adults (18-65 years), and 51 older adults (>65 years). One hundred seventy-five (38%) patients were randomly assigned to levetiracetam, 142 (31%) to fosphenytoin, and 145 (31%) were to valproate. Baseline characteristics were balanced across treatments within age groups. The primary efficacy outcome was met in those treated with levetiracetam for 52% (95% credible interval 41-62) of children, 44% (33-55) of adults, and 37% (19-59) of older adults; with fosphenytoin in 49% (38-61) of children, 46% (34-59) of adults, and 35% (17-59) of older adults; and with valproate in 52% (41-63) of children, 46% (34-58) of adults, and 47% (25-70) of older adults. No differences were detected in efficacy or primary safety outcome by drug within each age-group. With the exception of endotracheal intubation in children, secondary safety outcomes did not significantly differ by drug within each age-group. Interpretation: Children, adults, and older adults with established status epilepticus respond similarly to levetiracetam, fosphenytoin, and valproate, with treatment success in approximately half of patients. Any of the 3 drugs can be considered as a potential first-choice, second-line drug for benzodiazepine-refractory status epilepticus. Randomized Trial of Three Anticonvulsant Medications for Status Epilepticus Kapur J, Elm J, Chamberlain JM, Barsan W, Cloyd J, Lowenstein D, Shinnar S, Conwit R, Meinzer C, Cock H, Fountain N, Connor JT, Silbergleit R, NETT, and PECARN Investigators. N Engl J Med. 2019;381(22):2103-2113. doi:10.1056/NEJMoa1905795 Background: The choice of drugs for patients with status epilepticus that is refractory to treatment with benzodiazepines has not been thoroughly studied. Methods: In a randomized, blinded, adaptive trial, we compared the efficacy and safety of 3 intravenous anticonvulsive agents—levetiracetam, fosphenytoin, and valproate—in children and adults with convulsive status epilepticus that was unresponsive to treatment with benzodiazepines. The primary outcome was absence of clinically evident seizures and improvement in the level of consciousness by 60 minutes after the start of drug infusion, without additional anticonvulsant medication. The posterior probabilities that each drug was the most or least effective were calculated. Safety outcomes included life-threatening hypotension or cardiac arrhythmia, endotracheal intubation, seizure recurrence, and death. Results: A total of 384 patients were enrolled and randomly assigned to receive levetiracetam (145 patients), fosphenytoin (118), or valproate (121). Reenrollment of patients with a second episode of status epilepticus accounted for 16 additional instances of randomization. In accordance with a prespecified stopping rule for futility of finding one drug to be superior or inferior, a planned interim analysis led to the trial being stopped. Of the enrolled patients, 10% were determined to have had psychogenic seizures. The primary outcome of cessation of status epilepticus and improvement in the level of consciousness at 60 minutes occurred in 68 patients assigned to levetiracetam (47%; 95% credible interval, 39-55), 53 patients assigned to fosphenytoin (45%; 95% credible interval, 36-54), and 56 patients assigned to valproate (46%; 95% credible interval, 38-55). The posterior probability that each drug was the most effective was 0.41, 0.24, and 0.35, respectively. Numerically, more episodes of hypotension and intubation occurred in the fosphenytoin group and more deaths occurred in the levetiracetam group than in the other groups, but these differences were not significant. Conclusions: In the context of benzodiazepine-refractory convulsive status epilepticus, the anticonvulsant drugs levetiracetam, fosphenytoin, and valproate each led to seizure cessation and improved alertness by 60 minutes in approximately half the patients, and the 3 drugs were associated with similar incidences of adverse events (Funded by the National Institute of Neurological Disorders and Stroke; ESETT ClinicalTrials.gov number, NCT01960075.).


Nowadays, microbial infections and resistance to antibiotic drugs are the biggest challenges, which threaten the health of societies. Due to several pharmacological activities associated with Cynara cardunculus, such as hepatoprotective, antioxidative, anticarcinogenic, hypocholesterolemic, antibacterial, anti-HIV, among others, extracts from seeds, leaves, and flowers were tested in Escherichia coli cells. The sensibility of the Mid-infrared (MIR) spectroscopy allowed to perform a detailed analysis of the antimicrobial action of extracts in terms of their biomolecular changes. A comparative model based on several commercial antibiotics such as metronidazole, kanamycin, clarithromycin, chloramphenicol, and ampicillin, was developed. The clustering analysis was performed using unsupervised algorithms such as Principal Component Analysis (PCA), and Kohonen Self-Organizing Maps (SOM). The extracts characterized with antioxidant activity were clustered with antibiotics and presented a promissory antimicrobial activity. According to this preliminary result, it is possible to use the MIR spectroscopy and machine learning algorithm to discover promissory bio compounds characterized by antimicrobial properties, allowing to develop a platform to discover new bioactive molecules, reducing time and costs.


The nearly-incessant free oscillations of the Earth (not the larger, long-lived normal modes seen following intense quakes) were first observed by accident in the record of a tilt-sensitive instrument designed to study surface physics. Later tiltmeter studies demonstrated the usefulness of autocorrelation for the routine study of these normally short-lived eigenmodes. More recent studies suggest that many tilt-sensitive instruments are capable of observing these oscillations--if the low-frequency response of their electronics is not suppressed, as is customary with conventional designs.


Phase-transfer glycosylation of 4-methoxy-1H-pyrazolo[3,4-d]pyrimidine with the 2-deoxyribofuranosyl chloride 9 formed the N(1)-β-nucleoside 10a as main product (39%). As by-products the α-D-anomer 11a (7%) and the N(2)-isomer 12a (18%) were isolated. Assignment of these isomers was made on the basis of their 1H- and 13C-NMR spectra. Removal of the sugar-protecting groups yielded the 4-methoxy-nucleosides 10b, 11b, and 12b, respectively. Nucleophilic displacement of the 4-MeO-group gave the 2-deoxyribofuranosides 1–4 of allopurinol and 4-amino-1H-pyrazolo[3,4-d]pyrimidine.


IN THIS ARTICLE I am going to advance a hypothesis concerning the Biblical Nimrod, a man of Cushitic origin who became a Babylonian ruler. It has been suggested that Nimrod is identical with one of the kings of the first dynasty of Uruk, Gilgamesh (commonly) or Lugalbanda (Deimel). We have at present no certain historical reports of that old epoch. We know only the views of the Babylonian historians who left us the lists of Babylonian kings of the oldest times. The lists we have were written about 2000 B. C. Their truthfulness for later periods is generally proved by historic inscriptions from the time of Lugalzaggisi, king of Uruk. As for the older epoch the value of these lists is not yet certain. Besides, there are in the Babylonian literature some historical legends concerning the oldest kings of Uruk, but we have no means of learning their historical values. These conditions cannot encourage anyone to make an inquiry concerning the Biblical Nimrod. My reason for trying it lies in the curious notice that Nimrod was of Cushitic origin. In the Babylonian tradition we find Meskingasher, the founder of the first dynasty of Uruk, bearing some Hiamitic (Egyptian) features. Perhaps there is some connection between the Hamite of Uruk and the Cushite Nimrod. It is worth while to compare the Biblical notice of Nimrod with the views of the Babylonian historians concerning the first dynasty of Uruk. The results cannot be quite certain, but they can give some useful hints concerning the Old Babylonian history. The first book of the Bible says in the tenth chapter, vv. 8-12, as follows:


The aim of the publication is to build a general scheme of the history of the Azov Volunteer Battalion, using the contents of the Azov Battalion Archive of unregulated documentation in general and internal battalion orders in particular.

The research methodology involves the application of the principles of historicism, the usage of studying whole historical sources and being objective. Descriptive method, methods of classification and systematization as well as methods of analysis and synthesis have been used. The source base of the study is based on internal battalion orders and other materials of the archive of unregulated documentation of the Azov Battalion.

The scientific novelty is conditioned by the high source value of the materials of the Azov Battalion Archive, which are currently completely unexplored within the academic science; these materials are introduced into scientific circulation for the first time.

The conclusions of the study are the construction the general scheme of a history of the Azov Volunteer Battalion from the establishment of the unit on May 5, 2014 on the basis of the training and mobilization center "Cossack Legion" in the actually squatted building in the center of the Ukrainian capital to expand the unit to the regiment of September 17, 2014. Important milestones in the battalion's history are the redeployment of the unit from Kyiv to the Azov coast, participation in hostilities in the summer and autumn of 2014, including the liberation of Mariupol on June 13 and Mar'inka on August 4, and participation in the Ilovaysk operation in August and the defense of Mariupol in early September of that year.


Abstract : The purpose of this project is to determine the inherent limitations of sheet metal forming processes, to develop the knowledge to signifi cantly advance these, and to recommend the manner in which this can be accomplished. Principal areas of investigation are concerned with the effect that primary process variables such as velocity, temperature and pressure have on various classes of metals and alloys. This report presents the results of the experimental part of the program covering the first sixteen months. This experimental work was performed for tensile testing, free bulging of tubing and domes, and forming of parts with dies using a projectile impact tensile test fixture, low explosive - closed system, high explosive open system, electrohydraulic open system, elec tromagnetic system, and conventional presses. In addition, high-pressure rubber forming was in vestigated, utilizing both static and impact presses in conjunction with heat. (Author)


Benzoic acid, sorbic acid are widely used for food preservation. The analyses of these preservatives in 100 different
food products were performed. Therefore 100 samples including, 10 carbonated beverages, 20 jams, 10 jelly drinks,
10 jelly cups, 30 ready to serve drinks, 10 nectars, and 10 sauces were analysed by using high performance liquid
chromatography. The HPLC determination of the preservatives was performed using a reversed – phase C18
column and UV detection at 235 nm. Flow rate approximately 1.2ml/min. Eluent for HPLC, mix 50 volume parts of
Ammonium Acetate solution with 40 volume parts of methanol for HPLC and adjust to a pH of 4.5 to 4.6 with acetic
acid. The preservative concentration in samples was used as external standards for sodium benzoate and potassium
benzoate. Levels were compared with Food Act and Food Standards Regulation in Sri Lanka. Both benzoic acid
and sorbic acid were detected in a range of 1120ppm to 30ppm and 582ppm to 16ppm respectively. Although 65%
of the samples was not compliant with the Food Act and Food Regulations in Sri Lanka.


Abstract : These viewgraphs discuss integrated baseline review as presented at the 15th Annual Performance Management Conference held 2-5 May 1999 at St. Paul, MN.


Prognostics and health management (PHM) has emerged as an essential approach for preventing catastrophic failure and increasing system availability by reducing downtime, extending maintenance cycles, executing time repair actions, and lowering life‐cycle costs. This chapter provides a basic understanding of data‐driven diagnostics and prognostics. It reviews recent advancements of diagnosis and prognosis techniques with a focus on their applications in practice. The chapter discusses research opportunities that can lead to further improvement of PHM in both theory and practice. Bagging, also known as bootstrap aggregating, is an ensemble learning method that uses a series of homogeneous or heterogeneous machine learning algorithms to improve classification performance. Adaptive boosting is the first practical boosting algorithm and aims to convert a set of weak classifiers into a strong one sequentially. Prognostic techniques can be categorized into two groups: regression analysis and particle filtering.


B2 ordered FeAl films with a small, uniform grain size have been produced by rf diode sputter deposition on glass substrates. CoCrPt films grown on FeAl underlayers were found to have the (1010) lamellar texture. The in-plane coercivities (Hc) of the CoCrPt/FeAl films are comparable to those of the CoCrPt/Cr films and they can be further improved by inserting a thin Cr intermediate layer between the CoCrPt and the FeAl layers. By employing a MgO seed layer or a (002) textured Cr seed layer, (001) textured FeAl can be obtained. However, the (001) FeAl underlayer only induces a weak (1120) textured CoCrPt. Thus no improvement in Hc over those produced on unseeded FeAl underlayers was observed.


We present results on the growth of Ge islands into two-dimensional arrays by molecular beam epitaxy on Au-patterned Si. For a square array of Au dots, a two-dimensional square lattice of Ge islands extending over hundreds of microns has been produced. Islands in the patterned region grow between Au dots and have strikingly different shapes than islands on Au-free Si. For example, square base truncated pyramids grow on Si(0 0 1) while rod-shaped islands grow on Si(1 1 0). Characterization of island development on Si(0 0 1) shows three island shape transitions during growth with the final shape converging to that of the super-dome structure. For both Si(0 0 1) and Si(1 1 0) islands initially grow as ''lens-like'' structures before nucleating steep {1 1 1} side-facets and transforming into truncated pyramids or rods, respectively. r 2005 Elsevier B.V. All rights reserved.


The Message Queuing Telemetry Transport (MQTT) protocol is used in the Internet of Things (IoT) and Edge Computing for its lightweight and efficient data exchange capabilities. However, challenges like lack of fault tolerance on the broker end and limitations in storing unacknowledged messages in Quality of Service (QoS) higher than 0 have emerged. This paper proposes leveraging Blockchain technology to enhance fault tolerance in dead letter exchanges at QoS levels 1 and 2 and enable more efficient and secure data management through block storage of unacknowledged messages to address these issues. The proposed approach suggests using Blockchain to implement dynamic load balancing through Blockchain Naming Services, which involves hosting brokers under decentralized domain names on the Blockchain, monitored by a load balancer. In case of a broker failure, the load balancer can seamlessly migrate topics from the failed broker to the next available broker, ensuring uninterrupted communication between publishers and subscribers. This approach aims to improve the performance and reliability of the MQTT protocol while preserving its lightweight and minimal overhead nature. By leveraging Blockchain technology, this paper offers innovative solutions to overcome the limitations of MQTT and enhance its capabilities as a reliable and efficient data exchange protocol for IoT and Edge Computing applications. The findings of this research contribute to the growing body of knowledge on integrating Blockchain with MQTT and provide insights into how Blockchain can be used to enhance the fault tolerance and scalability of IoT protocols.


The Geologic Map Index of Alaska (Map Index) is an online, interactive web mapping application that provides access to an actively growing geographic index of geology-related maps of Alaska and adjacent areas. This online research tool provides the locations and outlines of most DGGS and U.S. Geological Survey (USGS) geologic and geophysical maps of Alaska in a single, interactive web map. It allows searches of the map database by geographic area of interest, keywords, themes, publishing agency, dates, and other criteria. The search results provide links to DGGS's comprehensive, multi-agency publications database, where users may view and download publications for free. No other geographic index of Alaska geologic maps exists at this time. Map Index provides access to traditional geologic maps, as well as geophysical, sample location, geologic hazards, and geologic resources maps. DGGS plans to add outlines and data to the application for remaining geologic maps published by DGGS, USGS, U.S. Bureau of Mines, and U.S. Bureau of Land Management. Reports without maps can be accessed through DGGS's comprehensive publications database, .


The Hill-Sachs lesion is an important indication of previous anterior shoulder dislocation. We created Hill-Sachs lesions by using cadaveric humeri. Roentgenographs of these cadaveric humeri in the standard projections were then taken. Under fluoroscopy, new projections of the cadaveric humeri were obtained. In a clinical study, 15 patients (14 men and 1 woman; age range, 23 to 63 years; mean, 30 years) with known recurrent anterior shoulder dislocations were evaluated by using standard and new roentgenographic projections. On the basis of the cadaveric and clinical studies, the optimal methods for detect ing Hill-Sachs lesions include the following three roentgeno grams : anteroposterior view of the glenohumeral joint with the humerus in 45° internal rotation, the notch (Stryker) view, and the modified Didiee view.


Heloniopsis koreana and Heloniopsis tubiflora (Melanthiaceae) are endemic herbaceous species of the Korean Peninsula. The Melanthiaceae family has been described as having seeds with small, underdeveloped embryos at the time of dispersal, and morphological (MD) or morphophysiological dormancy (MPD). However, there are few reports on embryo growth, morphology, and seed germination in Heloniopsis species. The aims of this study were to investigate embryo growth and seed dormancy, and to determine the type of dormancy exhibited by these species. The effects of incubation temperatures, light conditions, and gibberellic acid (GA₃) on dormancy break and seed germination were tested. Freshly matured seeds of the two species had small embryos that occupied about 9-11% of the length of the endosperm, and which increased by more than 300% in length before radicle emergence, indicating that the embryos are underdeveloped at the time of dispersal. Embryos in the seeds grew under warm temperature regimes (between 25/15℃ and 30/20℃). GA₃ application (tested only in the light) overcame seed dormancy and promoted germination. Approximately 30% of the seeds of H. koreana and approximately 40% of the seeds of H. tubiflora germinated in suitable environmental conditions (light and temperature) within 4 weeks. Therefore, 30-40% of the seeds of the two species exhibited MD, and the rest of the seeds had non-deep simple MPD. Light was found to be one of the critical factors for germination because no seed of either of the two Heloniopsis species germinated under constant dark conditions, and thus, these species have the potential to form a persistent soil seed bank. Understanding these germination requirements will help in development of effective strategies to increase the establishment of seedlings in their native habitat.


Nirmal Kumar Ganguly and colleagues call for a comprehensive policy for neglected diseases research in India to foster innovation in drugs, diagnostics, and vaccines, critical for evolving needs of elimination programmes


The Biotechnology and Pharmaceutical Industry has always stood up to the challenge of discovering innovative products fulfilling high unmet medical needs for mankind. The drug discovery and development pathway is very challenging and time consuming from efficacy, safety, regulatory and investments perspective. Hence, there is a significant need for collaboration among the biotechnology and large pharmaceutical companies to develop and commercialize their product innovations across the globe. This paper reviews the discovery and development of Selumetinib by Array Biopharma from year 2000 to 2019 when the USFDA accepted the first NDA filing for neurofibromatosis type one (NF1) disease. Array biopharma successfully developed several other drugs to the marketplace and several drugs to late stage registration trials either itself or in collaboration with strategic partners. These strategic partnerships helped mitigate risks in drug development and registration. This study of the clinical, regulatory and partnership strategy untaken for Selumetinib has created important contribution in the field of product life cycle management in the pharmaceutical and biotechnology industry.


The topic of research; Incidence of bailoterapia with Andean rhythms in the national coordination of people served in the center of care of the older adult "San Sebastian" in the period from July to November of 2012, chosen by the importance of the problem already that older adults need recreational activities that they To improve its mobility, it should be noted that the daily routine creates different psychological disorders, and as a consequence the lack of interest in any physical activity due to the age, the general objective was: Perform bailoterapia rhythms with Andean national to improve the coordination in the patients of the Center of care of the Older Adult "San Sebastian, where was justified by the need to improve motor coordination of older adults coming by a sedentary lifestyle, the methodology Used was the field research through the application of rhythms in the Andean bailoterapia who were accepted by the participants, the registration of the data in a form of observation, the same that was tabulated and graficada at the beginning and end of the investigation, with the help of a statistician, a situation that enabled us to fulfill the Proposed objectives, the results were important in function that helped demonstrate that patients improved psychomotor coordination, the results were able to build the conclusions and make recommendations.


This report is intended for use by those with an interest in Family Carer issues in Ireland.This report is a living document, and we will be updating it on a regular basis. The latest version is available at http://www.carealliance.ie/publications.php
• Should you notice any inaccuracies or omissions please inform us by email to firstname.lastname@example.com
• Should you be undertaking research in the area we would be delighted to receive your final report so we can consider it for inclusion in any updated versions. Please send to email@example.com


Inner hair cell (IHC) receptor potentials recorded from the first turn of the guinea pig cochlea phase‐lead the extracellularly recorded cochlear microphonic indicating a response during basilar membrane velocity towards scala vestibuli. This phase‐lead was reduced for higher frequencies, faster than could be expected from the effect of the membrane time constant alone suggesting that the IHCs changed from responding to velocity, to displacement. In order to resolve this question period histograms were generated from single units recorded in the spiral ganglion to frequencies between 40 and 500 Hz. Cells responded at low intensities during displacement towards scala tympani and at higher intensities this response changed to scala vestibuli velocity. We interpret this as being the effect of cochlear microphonic generated by the outer hair cells on the IHC synapse and the IHC receptor potential respectively and conclude that IHCs respond to basilar membrane velocity at least up to 500 Hz. Using the Mossbaue...


On the basis of matrix analytical theory,the identifiability of inertial moment parameters was studied. A linear regression model in term of the unknown parameters was derived from attitude dynamics equations; the condition number of regression matrix was defined as the quantitative index of identifiability degree; taking the maximum of identifiability degree as objective function,an optimal control model was built.The pseudospectral optimal control was employed to solve the command trajectory of control moment gyro and to improve the identification precision and convergence velocity. The method of dual-unscented Kalman filter identified parameters under simulated circumstances. Results demonstrate that the optimal excitation design can improve the performance of parameter's identification and has high robustness to inaccurate priori information.


To improve the water-resistance and physical properties of soy protein isolate (SPI)-coated paper, effects of concentrations of soy protein isolate and plasticizer were examined. Physical properties such as elongation strength (ES), elongation rate (E), water vapor permeability (WVP), and water solubility (WS) were evaluated. The film made from 5% soy protein isolate (SPI) and 40% glycerol (plasticizer) suggested a good application for a film preparation. SPI coated paper showed the highest ES (21.62 ㎫) and the lowest WVP (2.06 ngㆍm/㎡ㆍsㆍ㎩) and WS (1.17%). This study suggested that soy protein isolate (SPI) can be used as a coating material for the coated paper to improve the water-resistance.


We discuss fluorescence detection in two-dimensional interconnected solid and liquid-core ARROW waveguides. We demonstrate single molecule sensitivity and electrical control of analyte flow for deterministic generation of optical signals with ultra-high sensitivity.


This paper introduced the necessity and importance of early intervention work of railway new line housing construction professional,in light of the new situation of railway new line construction and operation management,how to organize the housing construction professional to early intervention work,discussed the construction,personnel management,intervention work key points and problems communication and solving mechanism of early intervention platform,so as to ensure the security successful launch of new railway.


Previously, we solved the Stokes problem using a new linear‐constant stabilized mesh‐free finite element based on linear Weighted Extended B‐splines (WEB‐splines) as shape functions for the velocity approximation and constant extended B‐splines for the pressure (Kumar et al., 2002). In this article we derive another linear‐constant element that uses the Haar wavelets for the pressure approximation and a quadratic‐linear element that uses quadrilateral bubble functions for the enrichment of the velocity approximation space. The inf‐sup condition or Ladyshenskaya‐Babus̆ka‐Brezzi (LBB) condition is verified for both the elements. The main advantage of these new elements over standard finite elements is that they use regular grids instead of irregular partitions of domain, thus eliminating the difficult and time consuming pre‐processing step. Convergence and condition number estimates are derived. Numerical experiments in two space dimensions confirm the theoretical predictions. © 2004 Wiley Periodicals, Inc. Numer Methods Partial Differential Eq, 2004.


This article begins from the awareness that in a world of affluence, millions are hungry. It addresses the question as to whether this is merely an economic issue or whether it also poses an ethical and theological dilemma, considering ways in which the situation we are living in challenges our faith in the transformation of bread and wine into the body and blood of Christ. It asks how, in the situation as it is, there is any possibility of believing in such a transformation. Finally it questions whether there is any relationship between hope for the transformation of hunger amidst affluence and belief in the transformation of bread into the body of Christ, and outlines a transformative eucharistic vision for the global Christian Church.


Abstract An assay for Bacillus stearothermophilus has been developed using thermophilic phage. The technique provides a convenient means of assaying samples for B. stearothermophilus at unselective temperatures and, under favourable circumstances, at ambient temperatures. In contrast with the viable-count assay, which scores for both cells and spores, the phage assay scores only for dividing cells. Most infectious centres were shown to represent infected bacteria rather than free phage. In a temperate environment the number of' dividing B. stearothermophilus cells in soil was found to be negligible.


The purpose of this study is to present theoretical evidence that can apply usefully to determine or establish strategic priority by evaluating selective attributes importance and satisfaction of taekwondo gymnasium using IPA method. Subjects were the 487 people who registered taekwondo gymnasium children`s parents in Seoul and Gyeonggi Province. Collected data were conducted several tests followed: frequency analysis, factor analysis and t-test using SPSS WIN Version 18.0 Program. As a result of these data analysis, the conclusions of this study are as follow. First, the variables that belong to 1 quadrant were safety condition, clean condition, sports facilities and maintenance of educational apparatus, air conditioning and heating, ventilation, stability of studio surrounding, harmful environment of studio surrounding, cleanliness of studio surrounding. Second, the variables that belong to 2 quadrant were instructor`s sincerity, instruction career, educational contents faithfulness, professionalism, kindness, personality and behavior, leadership, planning, interest, contents of taekwondo program, intimacy of taekwondo studio. Third, the variables that belong to 3 quadrant were variety of taekwondo program, age of instructor, sex of instructor, discount system of taekwondo goods, image of taekwondo studio, vehicle, distance. Fourth, the variables that belong to 4 quadrant were fitting room, shower room, lounge, lighting state, fully furnished, reputation, academic background of instructor, fee.


SYNOPSIS: This paper describes in detail a prediction about the responses of the soil and the RC diaphragm wall of a deep excavation in Taipei. The 21.8 m excavation was the deepest at the time, and it served as a good basis for testing previous back analysis results. As instrumentation records became available, updates were made and were passed to the contractor for the construction control purpose. The prediction was considered as a success.


This essay characterizes Japanese Brazilian ethnic identification across time. I discuss social relations in Japan before emigration, then organize the data on Japanese immigration in Brazil (i908-i988) according to the idea of stages in ethnic process. To clarify elements of the final stage, I examine the question of ethnic persistence and investigate whether segregation occurs because of choice or constraint. The final discussion provides an explanation for persistence of ethnic identity. Ethnic identification happens for different reasons at different points in the migration's history. For Japanese, ideological and emotional ties to the ancestral homeland are related to the international status of host and donor societies. The historical particulars are of critical importance to understanding the articulation of elements in a theory of migration.


Ecosystem services (ESs) are crucial for sustainable development, as they impact human well-being. However, changes in land use/land cover (LULC) caused by climate change and social development can negatively affect ESs, particularly in arid river basins. This study focuses on current and future changes in LULC in the Kaxghar River Basin (KRB) in Xinjiang, China, to determine how these changes will affect the region's ESs. The integrated PLUS-InVEST model was used to investigate the spatiotemporal distribution and changing patterns of habitat quality (HQ) and carbon storage (CS) under the natural increase scenario (NIS), economic development scenario (EDS), and water protection scenario (WPS). Additionally, the Ecosystem Service Contribution Index (ESCI) was also calculated to evaluate the contribution of LULC changes to ESs. The results show the following: (1) from 2000 to 2020, the average value of HQ in the KRB gradually decreased from 0.54 to 0.49 and CS trended slightly upward, with a total increase of 0.07 × 106 t. Furthermore, the changes in CS were highly consistent with changes in LULC. (2) From 2020 to 2030, the area of low-grade (0–0.2) HQ saw a continuous increase, with the fastest growth occurring in 2030 under the EDS. Meanwhile, under the WPS, HQ significantly improved, expanding by 1238 km2 in area. Total CS under the three test scenarios tended to decline, with the NIS showing the smallest decrease. (3) The expansion of cropland and unused land had a negative impact on ESs, particularly on CS, whereas the conversion to grassland and forestland had a significant positive impact. In conclusion, these insights will enrich our understanding of ESs in the study area and contribute to balancing the relationship between ecological conservation and socioeconomic development in the Kaxghar River Basin, as well as in other parts of China's arid Northwest and similar regions around the world.


The present study aims to prove hypotheses regarding artificial intelligence integration in retail value chains in the post-Soviet economic space. Hypotheses were proven within a comprehensive research project based on the use of quantitative research methods (questionnaires), which allowed studying the opinions of 512 retail managers in Azerbaijan, Kazakhstan, and Tajikistan. A specially designed questionnaire eliminated ambiguity in results interpretation by including both simple closed questions with a single choice and questions using a Likert scale. All the formulated hypotheses were proven, leading to the conclusion that the retail market of the post-Soviet economic space is not ready for the introduction of robotization and full automation of retail stores. The study results can be used by retail managers in the post-Soviet economic space as they choose the direction of artificial intelligence integration.


A methodology supporting the cascade training strategy of national scope was designed to establish a system of training and/or improvement of human resources of the national health system in the thematic of clinical assays, considering the identification of learning needs of the members of the research team, the topics that should be included in the upgrading course, and the organizational figures to be used in the training of the researchers.


Mobility has been suggested as a way to improve the coverage of wireless sensor networks. However, increased mobility to improve coverage makes a rise in the consumed power. The best proposed solution in such settings is virtual movement algorithms, although they are not effective in clustered networks. In this paper, an iterative structure has been proposed for virtual movement algorithms which in addition to solving the problem with clustered networks, ensures the minimal mobility required for optimal coverage. Simulation results of the proposed algorithm indicate its efficacy is more than the VEC, FBPC and FOA algorithms. The algorithm allows the desirable coverage and high convergence of the network while keeping the average movement for each node low.


Most organizations have traditionally designed their compensation systems around specific jobs. The wage and salary structure of these systems has typically been based on job analyses and evaluations; this process determines a job's worth and salary range. In recent years, however, a new alternative to this job-based approach has been developed ; this new system pays employees for the skills and knowledge they possess, rather than for the job they do or a particular job category. A variety of terms have been used to refer to this new compensation approach: skill-based pay, multiskill-based pay, knowledge-based pay, and pay-for-knowledge. The time has now come to spell out the meanings of and distinctions between these


Abstract Aims Multiple re-entry circuits may operate simultaneously in the atria in the form of dual loop re-entry using a common isthmus, or multiple re-entrant loops without a common isthmus. When two or more re-entrant circuits coexist, ablation of an individual isthmus may lead to a seamless transition (without significant changes in surface electrocardiogram, coronary sinus activation or tachycardia cycle length) to a second rhythm, and the isthmus block can go unnoticed. Methods and results We hypothesize and subsequently illustrate in three patient cases, methods to rapidly identify a transition in the rhythm and isthmus block using local electrogram changes at the ablation site. Conclusion Local activation sequence changes, electrogram timing, and the behaviour of pre-existing double potentials can reveal isthmus block promptly when rhythm transitions occur during ablation of multiloop re-entry tachycardias.


Objective To compare field deratization effect of 0.005% bromadiolone and 0.05% diphacine-Na in city village of Nanning.Methods Determination of rodents density with the bait steal gauging,feeding of baits for four days and calculating the deratization rate.Results Both poison bait's palatability had not been found any differences,the deratization rate was 91.8% and 95.2% respectively.Conclusion Two bait's palatability and effect were all same,and suitable for deratization in city village of Nanning.Rats have no resistance to two rodenticides.


Significance Many biological processes are inherently physical in nature. Increasingly, biologists are proposing that the mechanical properties of tissues are critical for processes such as embryonic development and the progression of diseases including cancer and chronic inflammation. However, currently available methods are insufficient to quantitatively test hypotheses that concern the physical properties of living tissues. We introduce a method of three-dimensionally mapping the absolute stiffness and viscosity of tissue in a nontoxic fashion using a multipole magnetic device. By applying our method to the embryonic mouse limb bud, we show how a previously unrecognized distribution of physical properties leads to an important hypothesis, namely that cells move up a stiffness gradient to shape tissue during embryonic development. Numerous hypotheses invoke tissue stiffness as a key parameter that regulates morphogenesis and disease progression. However, current methods are insufficient to test hypotheses that concern physical properties deep in living tissues. Here we introduce, validate, and apply a magnetic device that generates a uniform magnetic field gradient within a space that is sufficient to accommodate an organ-stage mouse embryo under live conditions. The method allows rapid, nontoxic measurement of the three-dimensional (3D) spatial distribution of viscoelastic properties within mesenchyme and epithelia. Using the device, we identify an anteriorly biased mesodermal stiffness gradient along which cells move to shape the early limb bud. The stiffness gradient corresponds to a Wnt5a-dependent domain of fibronectin expression, raising the possibility that durotaxis underlies cell movements. Three-dimensional stiffness mapping enables the generation of hypotheses and potentially the rigorous testing of mechanisms of development and disease.


[Objective]To observe the expression of osteogenic growth peptide(OGP) gene,which had been transfected into rabbit bone marrow stromal cells(BMSC) by adenovirus,and detect the proliferation and differentiation of rabbit bone marrow stromal cells after gene transfection in vitro.[Methods]pcDNA3.1-OGP was constructed by using gene clone and recombined technique.With the help of lipofectamine 2000,BMSC were transfected with pcDNA3.1-OGP.The positive cell clones were selected with G418.The expression of OGP gene was observed by RT-PCR.Alkaline phosphatase(ALP) activity and type I collagen in pcDNA3.1-OGP transfected bone marrow stromal cells were measured to observe the differentiation from bone marrow stromal cells into osteoblast lineage.[Results]The pcDNA3.1-OGP vector was constructed successful.According to analysis of RT-PCR,alkaline phosphatase(ALP) and type I collagen assay showed that OGP gene could be expressed in BMSC,and could induce bone marrow stromal cells differentiation into osteoblast lineage.[Conclusion]The pcDNA3.1-OGP vector can be constructed successfully and its expression is confirmed in BMSC.The expression of OGP in bone marrow stromal cells can induce BMSC differentiation into osteoblast lineage.


Objective:To study the curative effect of different therapies on intervertebral space infection in rabbits.Methods:The model rabbits with intervertebral space infection were stablished by injecting Staphylococcus aureus into the intervertebral space,and the infection was confirmed by radiograph,MRI,ESR,and serum level of CRP.Thirty-six model rabbits were randomly divided into surgical and antibiotic treatment group(SAT),antibiotic treatment group(AT) and non-treatment group(NT).The curative effects were compared among the three groups.Results:NT group:the temperature,ESR and level of serum CRP were abnormal and the clinical symptoms deteriorated;the fatality rate was high(66.7%) and cure rate low(16.7%).AT group:the temperature,ESR and level of serum CRP recovered slowly and the clinical symptoms were uncatabatic;the fatality rate was high(50.0%),disability rate high(16.7%) and cure rate low(33.3%).SAT group:the temperature,ESR and level of serum CRP recovered quickly and the clinical symptom improved obviously;the cure rate was high(91.7%) and fatality rate low(8.3%).The curative efficacy in SAT group and AT group was better than that in NT group(P0.01 and P0.05).Conclusions:The anterior debridement can radically eliminate the infection tissues,so the temperature,ESR,level of serum CRP and the clinical symptoms improve quickly after surgery.


This study believes that information security is vital in protecting information resources (information systems as a whole) and use it as strategic resources for competitive advantages as part of organizational objectives. Having a secured strategic information resources allows organizations to be dynamics in the unpredictable business environment. This paper discusses the integration both concepts of information security and organizational agility to become a solid concept, in the effort of constructing a theoretical model for further study. There are several theories in relation to information security practices and organizational agility such as Sociotechnical System Theory; Social Cognitive Theory; Integrated System Theory; Resource Based View and Dynamic Capabilities are adapted and served as underpinning theories in providing insights and guidance for the development of theoretical model for this study.


Magnetic cylinders on an air table behave similarly to atoms in many face‐centered metals like aluminum or copper. They qualitatively exhibit the striking properties of a split‐interstitial point defect (dumbbell): the structure, the localized and resonance vibration modes of a symmetric dumbbell; its effect upon the shear modulus; and the structure of an unsymmetric (mixed) dumbbell, containing a foreign atom. All effects can be shown to a large audience by means of a transparent air table put on an overhead projector.


In urban Indonesia, more than 40 million people rely on groundwater self‐supply, but the extent to which self‐supply delivers safe water and the associated risk factors for fecal contamination remain unclear. This study quantified Escherichia coli (E. coli) for 511 self‐supply sources and at point‐of‐use for 173 households in the Indonesian cities of Bekasi and Metro. A structured questionnaire collected information about the household, water sources, and potential contamination sources. Univariate and multivariate logistic regression analysis examined risk factors for fecal contamination. E. coli was detected in 66% of sources, including 55% of boreholes, 64% of protected dug wells, and 82% of unprotected dug wells. Widespread boiling of water meant microbial quality improved significantly between source and point‐of‐use, with E. coli detected in 30% of self‐supply samples at point‐of‐use. Unprotected dug wells were significantly more likely to be contaminated than boreholes. In Bekasi, the analysis found a significant association between presence of E. coli and sanitation systems located within 10 m of the groundwater source. In Metro, poorer households had significantly higher odds of contamination than wealthier households. Other significant factors included shallower borehole depths in Bekasi, use of a rope and bucket, and absence of a concrete platform in Metro. In Bekasi, E. coli concentration at source was significantly associated with water quality at point‐of‐use. Risk of fecal contamination could be reduced by supporting households to invest in improved protection, and by facilitating promotion for safe household water treatment. Support for self‐supply improvements should be weighed against the expansion and improvement of piped water services.


The problems of huge route tables and network bottleneck in IPv4 should be solved in IPv6. This paper analyses the cause of the problems, which is related to that methods of dividing networks and distributing IP address in IPv4. It presents a solution to these problems,and proves its validity.


The subject of interest of the author of the text is the common good as an inalienable element of the organization of the human community. The paper consists of three parts. The first part analyses the need for a common good as the basis of social and political life. The starting point was the distinction of four forms of common life (community, society, political body and state), defining the nature of society, presentation of three forms of relationship between man and society (individualism, collectivism and personalism) and identifying problems related to the definition of the common good. In the second part, the author presented a reflection on the procedural common good in the liberal tradition, the issue of impartiality and identification of the common good in the process of the debate. In the third part, attention is paid to the personalistic view of the common good, which is based on the integral development of personal human nature in the framework of the appropriate institutions and structures. This understanding of the common good is, in the author's conviction, the best point of reference in social and political life.


Introduction: the upper digestive bleeding is the blood escape to the lumen of the digestive tube, between the upper esophagus and the Treitz angle. It is a common cause of consultation and hospitalization in the Emergency Services. Objective: to identify the prognostic factors of death in patients with upper gastrointestinal bleeding. Method: it was performed a cohort study in patients with a diagnosis of upper gastrointestinal bleeding, who were hospitalized in the service of General surgery at "Carlos Manuel de Cespedes" Provincial University Hospital in Bayamo, since May 1, 2008 until May 31, 2009. Results : the logistic regression model showed that severe bleeding (OR 17.704, 95% CI 7,653- 33.089) followed by hypovolemic shock (OR: 9.428, 95% CI 1.784 to 29.539) and heart failure (OR 5,604 CI 95% 2,539- 32.085) evidenced an independent, statistically significant relationship with the risk of dying. Conclusions:  it can be said that with the values obtained by adjusting the logistic regression function for independent factors influencing death, you can estimate the risk of death of our patients.


To extract a precise target position in the presence of infrared countermeasures and significant noise, we propose a new algorithm based on the instantaneous frequency (IF) estimation of the sinusoidal frequency modulation (SFM) signals for a fixed-reticle seeker. To esti- mate the IF for target position extraction, the proposed algorithm maps the multicomponent SFM signal into the time-frequency plane to exam- ine its time-frequency distribution, and then applies the Hough transform. The simulation results show that the proposed algorithm can extract the target position efficiently in the presence of flare countermeasures and noise. © 2000 Society of Photo-Optical Instrumentation Engineers. (S0091-3286(00)00209-9)


This article analyzes questions arising from a choice of available cloud computing services. Precisely what type of services should an organization choose? The article aims to introduce decision-making process according to the best practices. In order to describe this decision-making process we divide organizations into classes and for each class we recommend one or more available types of suitable cloud computing services. Moreover, there are introduced interesting cloud computing provider practices and service aspects including service operation, service parameters and service costs There are also introduced steps for customers how to deal with mentioned aspects.


The flax short fiber was dyed by using ractive dye and penetrant X.Basing on study of dyeing percentage,dye fixation,breaking strength,color fastness and K/S value,dyeing process of the flax short fiber was optimized.The processing capacity and spinnability of the linen was improved significantly


The authors present data concerning alcohol consumption at one commuter university and discuss the data's implications for reaching educational goals.


The present invention, in an oligonucleotide containing at least one secondary structure capable of modifying or inhibiting expression of a target gene in vivo or in vitro, is one or more secondary structure, oligo on the target nucleic acid characterized in that it comprises a complementary nucleotide sequence on one and / or the other end of the antisense sequence by one antisense sequences and if it is selected by the collapse such forms when nucleotides fixed It relates to oligonucleotides. The present invention also relates to pharmaceutical compositions comprising said oligonucleotides.


With the increasing usage of multimedia technologies, image compression requires higher performance as well as new features. To address these needs in the specific area of continuous tone still image encoding, a new standard is currently being developed, JPEG2000. We first present an overview of this standard. We are interested in evaluation of its performance by means of Kakadu software.


Formaldehyde vapour monitoring was conducted over the period July 1993 to September 1995 in the Human Anatomy Laboratory of the Faculty of Medicine; University of Natal. During the initial study, ambient levels of formaldehyde vapour exceeded the American (ACGIH) threshold limit value (TLV). An intervention in the form of ventilation controls was implemented and proved to be effective in reducing formaldehyde vapour levels. Whether that reduction is sufficient to prevent long-term health effects such as neoplasms and sensitisation remains to be established. The use of alternative methods of environmental control of exposures to formaldehyde are discussed and recommendations are made to reduce the exposure of workers in such situations.


In a traditional low-level hardware architecture,an interface can only be connected to the same kinds of devices.A solution of the intelligent interface technology that can connect an interface to heterogeneous devices is presented.Combining the audio system with the intelligent interface technology,further improved the application of the available devices and the utilization of existing resources are improved,and the common USB storage devices and SD memory devices are supported.


Our hundred and twenty, day old boiler chicks were randomly divided in to four groups viz. Group A (control), B (received aflatoxin @ 0.5 ppm and ochratoxin 0.5 ppm in diet), C (normal diet with probiotic, Sacchromyces boulardi @ 10 mg/ kg feed) and D (toxins as in group B with probiotic as in group C), containing 30 birds each, for a period of 6 weeks. Significant decrease in hemoglobin and PCV was observed in toxin fed birds along with serum proteins, albumin, globulin and A: G ratio when compared to the controls. Serum creatinine and SGPT levels were high in toxin fed birds. The genomic mean of antibody titers organist New Castle Disease were significantly low in toxin fed birds indicating immunosuppression. Sacchromycesboulardi appeared to act as probiotic and helped in combating the adverse effects of toxins, when compared with the haematobiochemical parameters.


Peter Newmark (1916-2011) was one of the representative figures in translation field of the English-speaking countries in the twentieth century. The paper mainly introduces Newmark's viewpoints on translation theory, especially his basic principles of the Communicative Translation Theory, that is, the principle of receptor-oriented strategies, the principle of equivalence-expected effect as well as the principle of information accuracy. It is based on text type and language function to translate, which makes the translation smoother and clearer to the target language readers. In that case, it can reduce the understanding obstacles of the foreigners.


Independent unbiased critical assessment is of the utmost importance in scholarly publishing, and, like all journals, JEB relies heavily on the expertise and experience of its Editors, Editorial Board and Peer Reviewers to control the quality of the research we publish. With the number of published


In this paper application of micro-ring resonator as an amplifier is proposed by suitably doping the ring and confining the coupled wavelength to undergo required number of rounds. Amplification otherwise attained using long fiber waveguides can be obtained within a small structure of ring resonator.


Use of an alpha-2-delta ligand, or a pharmaceutically accepable derivative thereof, for the manufacture of a medicament for the treatment of LUTS, other than urinary incontinence, associated with OAB and/or BPH.


Objectives To investigate the clinical nurses' job satisfaction and influencing factors,and to provide bases for improving the job satisfaction of clinical nurses.Methods A total of 143 clinical nurses were recruited and investigated with a self designed questionnaire and a job satisfaction questionnaire.Results The overall score of clinical nurses' job satisfaction was 151.83±27.22,and the 1owest satisfaction was welfare and the highest one was working atmosphere.Multiple regression analysis showed that influencing factors of clinical nurses' job satisfaction included clinical nurses' level of education and marital status.Conclusions Improving the level of education of clinical nurse can improve clinical nurses' job satisfaction and stabilized the nursing team.


In this study, we present methodologies to process big data in complex multimedia forms for sports analytics. Sports analytics is the management and analysis of data collected from sports games to quantify past results and predict future outcomes. In basketball, the on-ball screen is a dynamic offensive strategy that involves the movement of multiple players and the ball to create an effective shot attempt. It is a fundamental play employed by all teams in the National Basketball Association (NBA), the highest level of competition for basketball. The analysis of a basketball team and its strategies must first include the identification of such plays. With the presence of sophisticated data collection and analysis tools, this paper proposes methodologies to extract, transform, and analyze player motion-tracking data in NBA games to automatically identify the presence of on-ball screens, with 90% sensitivity, an 8% improvement on existing literature.


The present invention discloses an implantable medical diagnosis is one kind of seals is provided, comprising an implantable electronic medical unit further comprises a disk-shaped bottom shell, for accommodating the bottom case equipped with implantable electronic medical receiving cavity unit; further comprising a spacer plate for covering the opening of the bottom case; the disc-shaped separator plate is provided for placement of the antenna housing; housing further includes a cover for covering an opening in the housing; in the housing provided for letting medical implantable electronic unit and a communication antenna communicating with the outside; reasonable structure, the human body without tingling, provided reasonable internal structure, an antenna placed in a wide frequency range within which the isolation is better, high gain; provides better installation module is implantable medical diagnostics development, companies only need to be designed to present the bottom case into the shape and thickness of their size or implantable electronic medical unit will be able to achieve a better quality of communication.


A recent report in the British Journal of Psychiatry ([Fazel & Benning, 2009]) called attention to the alarming suicide rate in incarcerated women. Spanning a 25-year period (1978–2004), the data p...


The long Afghan conflict has resulted in an extensive destruction of Afghanistan's state justice institutions that existed prior to the former Union of Soviet Socialist Republics (―USSR‖) invasion of the country in December 1979. The destruction has not only included extensive damage to buildings, office furniture, official records, legal resources, and essential office equipment, but also the death, imprisonment, and migration of hundreds of professional justice officials, including qualified judges, prosecutors, police officers, and prison wardens.1 Following the collapse of the Taliban regime, the Bonn Agreement of December 2001 authorized formation of the Afghanistan Judicial Commission.2 The Bonn Agreement tasked the Commission—with help from the United Nations and other international actors—to ―rebuild the [Afghan] domestic justice system in accordance with Islamic principles, international standards, the rule of law and


The in-situ reconstruction of electrocatalysts with the changes in crystal structure and composition is a universal process, enabling the modulation of active sites for high catalytic performance. Therefore, tracking the...


The presence of particulate matter of various sizes, generally classified as dust, is an important factor affecting air quality in outdoor and indoor scenarios. Many industrial processes require clean rooms where dust concen- tration has to be kept below certain thresholds in order to assure the success of the manufacturing process or the quality of the finished product. Applications which need precise dust quantity measurement presently use complex and expensive systems. In the mean time, wireless sensor networks (WSN) have emerged as a tool which promises higher resolution spatial measurements than conventional devices. Beside usual sensors, many WSN producers offer data acquisition expansion modules which supply general purpose analog and digital inputs allowing for the connection of external sensors. This paper proposes combining the two technologies by integration of an optical interferometer dust sensor with a conventional sensor networking platform through a data acquisition module. The system design and description as well as an experimental evaluation in a laboratory setting are presented. We evaluate the results obtained by comparison to a high precision laser air quality monitor for 0.5 and 2.5 micron particles. The results are encouraging and show that our approach is viable for testing outside the laboratory environment, in a real world deployment.


The present study was based on the development and organoleptic evaluation of gluten free bakery products using quinoa (Chenopodium quinoa) flour. Five quinoa based gluten free bakery products were prepared by supplementing quinoa flour at 5, 10 and 15 percent with rice and oats flour. The developed products along with their control samples were organoleptically evaluated using eight-point hedonic rating scale and were also nutritionally analyzed by using standard methods. Quinoa based gluten free bakery products namely cookies, cakes, muffins, pies and tarts were found to be highly acceptable at 10 percent level of supplementation of quinoa flour with rice and oats flour having overall acceptability scores of 7.46, 7.54, 7.32, 7.78 and 7.56 respectively. The developed products were found to have increased nutrient content in terms of protein and fibre. The highest protein content was found in muffins i.e. 8.4 percent and fibre in pies i.e. 1 percent. The calcium, iron, magnesium and zinc content of developed products ranged from 13.5-34.84 mg, 1.34-1.73 mg, 12.22-33.41 mg and 0.13-0.54 mg. The amino acid content of developed products i.e. tryptophan, methionine and lysine was also found in the range of 52.75-100.23 mg, 79.13-209.93 mg and 96.71-435.88 mg per 100 g protein. The incorporation of quinoa flour in developed products also resulted in increase in anti-nutritional factors i.e. phytin phosphorus and total saponins. Awareness was created regarding quinoa based gluten free bakery products through lectures, individual consultation and booklets. These products can thus prove as a boon for celiac patients.


Introduction Conventional 3D seismic pre-stack data is usually gathered to CDP bins of size (∆x,∆y) in (x,y) space. Traces from shot point (xs ,ys), receiver point (xr ,yr), and with mid-point xm=(xs+xr )/2 & ym=(ys+yr )/2 falling within a bin will be stacked together to generate the stacked trace for that bin. The underlying assumption for this process is that the gathered traces to be stacked are virtually the same because of the small size of (∆x,∆y). When the size of bins increases or data has complex structure, the difference among these to-be-stacked traces increases. It is therefore desirable to generate stacked traces by way of interpolation in order to increase resolution.


It was found that GaAs melt can be purified in-situ by our new method of bubbling distillation technique. The degree of the purification can be detected by the measurement of the electric conductivity of the melt. With this technique homogeneouse undoped semi-insulating 2 inches in diameter GaAs single crystals can be grown with high reproducibility.


Entamoeba histolytica is a protozoan parasite, causative agent of amoebiasis in humans and is one of the leading causes of death among parasitic infections worldwide. In this study, strains of different virulence and genetic background of E. histolytica were analyzed by the technique of random amplified polymorphic DNA (RAPD); where it was found that the amplification products of the RAPD for strains of E. histolytica with different virulence, showed genetic fingerprints that allow to discriminate between strains of the same species, even closely related, where the most marked difference is between the strains with different genetic background. These variations in the genotype could be reflected in the parasite phenotypes and explain their implications in virulence, molecular diagnostic and epidemiology. Palabras Clave Amibiasis; Huella génica; Entamoeba Histolytica; Epidemiología molecular; RAPD


Product innovation research has matured substantially in the last two decades. A great deal of knowledge has been produced on various aspects of the discipline, so it is of interest to assess the state of the art the scientific community has reached in this discipline, and the route it has taken. This perspective is investigated through a bibliometric study of the Journal of Product Innovation Management (JPIM), arguably the most important specialized journal on this topic. The work reviews all journal article contributions in JPIM from 1984-2004 in determined time frames, assesses the citations contained in these articles, identifies how the citations are related to the various topics of production innovation research (topic-related citation variety, topic-related citation consistency, variation in topic-related citation pattern) and offers a retrospective examination of the evolution of the field. The overall analysis of citations shows that most articles in JPIM cite at least one of the Top 50 works identified by this study. This testifies the strong impact of the most influential works on the intellectual structure of product innovation research. The observed citation pattern suggests that the Top 50 articles gained influence in product innovation research either because they represent a relevant contribution on a fundamental topic that already has been authoritatively studied or because they investigate in a relevant manner a new topic. The article suggests that JPIM might benefit in its aim to consolidate its position as one of the top academic business journals if published articles increasingly drew on the most influential works to inform their research design, and explicitly stated the theoretical underpinnings they draw on in their research design. Overall, the analysis of the sub-periods (1984-1988, 1989-1993, 1994-1998, and 1999-2004) provides evidence for the maturation of new product innovation research. Books covering a wide range of topics are replaced by journal articles addressing a specific topic; over time, specific topics emerge and become influential for the discipline's intellectual structure; articles published in JPIM augment their methodological rigor and increasingly address contingency factors. The article also notes that obtaining relevance for JPIM authors constitutes a necessary condition for being considered by management researchers at large as an influential contribution to product innovation research.


An adequate natural language description of developments in a real-world scene can be taken as proof of "understanding what is going on." An algorithmic system that generates natural language descr...


Inspired by the "Five product levels"in Management theory,the author divided interpreting product into "Core Benefit","Formal Product","Expected Product"and "Augmented Product". By reviewing related literature in this field,the author proposed the "Expected Product Model",which indicates 3 potential gaps: 1) the potential gap between users' expected product and actual interpreting product; 2) the potential gap between interpreters' expected product and the actual interpreting product;3) the gap between the interpreter and the users,which means the users' need may not always be fully understand by the interpreter. Therefore,the interpreter has to constantly negotiate between professional norms and user' expectation so as to ensure interpreter quality and customers' satisfaction. Based on the above model,the author further described the possible delivery process of "Expected Product"in interpreting and discussed its indication.


This chapter focuses on discourse in organizations and workplaces and will discuss a number of studies which explore the complexity and diversity of communication in modern working life. With a theoretical orientation towards sociology, organization/network theory and social constructivism, researchers have sketched the macro-frames which in) uence discourse at various levels within organizations. Studies of the correspondence between organizational structure and discourse will be used as a background for presentations of analyses which try to grasp and understand communication in the modern organization from different viewpoints and with a focus on different problem areas. The theoretical and methodological perspectives of these analyses include textlinguistics, ethnography, critical discourse analysis, interactional sociolinguistics and conversation analysis. A relevant question for our understanding of modern working life is related to the effects of technological advance and globalization. The conditions for professional discourse have been in) uenced by a series of changes taking place in recent decades. Technological advances have facilitated a globalization of working life, while lifelong learning, ) exibility, mobility and diversity have come to be key values in the global economy. In organizations throughout the world, we - nd a widespread use of technology and increased reliance on the internet for internal and external communication. Another striking feature, made possible of course by the technological advances, is the globalization of the business world and the job market. Throughout the world, we - nd transnational companies which use English as their corporate language and employ multilingual people who can move between jobs, between branches and between countries. The workforce mobility and workplace diversity which characterize a globalized economy also raise issues of multilingualism and multiculturalism to the surface, both in relation to the organization as a whole and to workplace practices. For employees this new situation has come to entail different and higher demands for literacy and communicative skills. The purpose of this chapter is to deepen our understanding of the discourserelated problems facing managers and employees in the globalized economy. In the various sections of the chapter I discuss these problems from different viewpoints. First, I explore the correspondence between organizational structure and discourse at a more general level, where I use examples from analysis of small


The problem in this study is whether the amount of funds collected, mortgage interest rates, inflation rates and the money supply affect credit allocation Micro Enterprises, Small and Medium Enterprises (UMKM) in General Bank in Indonesia. This study aims to determine whether there is influence of the amount of funds collected, mortgage interest rates, inflation rates and the money supply on credit allocation Micro Enterprises, Small and Medium Enterprises (UMKM) in General Bank in Indonesia.
The population in this study are all listed General bank in Bank Indonesia in 2013. This study uses census where all commercial banks contained in the study period used as the object of research. This study uses 36 times the observation (time series data) from january 2010 to december 2012. Sources of data in this study using secondary data obtained from the website www.bi.go.id. Data analysis method used in this study is multiple regression analysis using SPSS 16.0.
The results of this study indicate that the value of t-table is 2,042 at α = 0.05, each t-count value is below the value of t-table (t-count 0,05, which means the amount of funds collected, mortgage interest rates, inflation rates and the money supply has no effect partially and simultaneously on credit allocation Micro, Low and Medium Enterprises (UMKM) in General Bank in Indonesia.
The conclusion of this study is that the amount of funds collected, mortgage interest rates, inflation rates and the money supply has no effect on credit allocation Micro, Small and Medium Enterprises (UMKM) in General Bank in Indonesia.


Background
The panhypopituitarism is a rare endocrine system disease; the clinical presentation of a panhypopituitarism patient can vary from asymptomatic or subclinical cases to life-threatening myxedema coma.
Case report
Our patient is a 55 years old woman who was presented to emergency department with chief complains of weakness. After necessary workup, panhypopituitarism was diagnosed.
Discussion
There are different diagnoses for weakness. In patients with vague complaints such as weakness, we should take their history carefully and perform clinical examinations to reach a definitive diagnosis.


Through the elaboration on the core competitiveness of travel agency,it analyzes the current development of travel agencies in the city of Yangzhou,and discusses the cultivation of competitiveness from six aspects: the improvement of human resources management,the construction of core culture,the development of featured brand,the enhancement of marketing competence,the creation of service-oriented products and the promotion of innovative ability.


The land market in Ukraine is currently being formed. Therefore, it is now especially important to master the experience of using the mechanisms of regulation of this important market, which have undergone a long and successful testing in foreign countries. The article reveals the main directions of international experience in regulating the market of agricultural land.To ensure the optimal distribution of land among users and for the efficient functioning of the land market in most countries of the world, land policy is structured in such a way that agricultural land is cultivated by those who are able to ensure its most productive use. The article analyzes the possibility of applying this experience in Ukraine on the basis of generalization of modern foreign practice. The agricultural land, in contrast to the land for industry, transport and other industries, is the main means of production. The article notes that the current model of state regulation of the land market can lead to the monopolization of such markets and the acquisition of agricultural land by large corporations. There are considered the opinions of various authors on this issue, and has defined the need to form the main aspects necessary for the efficient use of land resources.The example of individual countries shows that the lack of active state intervention in market turnover has led to the monopolization of agricultural land by large corporations. It is concluded that at the present stage of implementation of the policy that ensures the efficiency of land use in agriculture, the state should strengthen the functions of regulating land use processes. There were some specific proposals for improving the system of regulation of land relations in agriculture, which should play a progressive role in the further development of the state.
JEL classіfіcatіon: H3, H2


An expeditious synthesis of highly substituted benzenes with electron-withdrawing or electron-donating substituents is -described and illustrated by carbanion-induced ring transformation of 2 H-pyran-2-one with malononitrile in excellent yield. The -novelty of the reaction lies in the creation of an aromatic ring at room temperature from a six-membered lactone under mild reaction conditions.


PURPOSE: A water tank for fire fighting is provided to immediately supply fire staffs with water in a fire scene by being delivered by a helicopter. CONSTITUTION: A water tank for fire fighting is constituted as follows. The water tank for fire fighting is equipped with a water supply bag(10) receiving water and is formed of a loop capable of lifting by a helicopter. The water supply bag is manufactured into a pouch shape by connecting melting-attaching type waterproof fabrics formed of a thermoplastic fiber layer by welding. In the bottom of the water supply bag a water supply hole(12) is formed.


Computer graphics company modernizes pyrotechnics Fireworks have a way of making any occasion a special celebration-both adults and children respond enthusiastically to the impact and intensity of the colorful displays. Digital Effects, Inc., has found that computer graphics displays can convey almost the same excitement. The New York film-production house, which specializes in computer graphics animation, modernized the ancient art of pyrotechnics by producing a computer-generated fireworks display. The 30-second commercial, produced for NCR Corporation on its 100th anniversary , features an array of colorful Chinese chrysanthemums and rockets in a smoke-filled night sky. The presentation opens with a sprinkling of blasts that build into brilliant explosions (as seen in the photos at left). The Digital Effects production team studied videotapes of live fireworks displays produced by Felix Grucci, a well-known pyrotechnist. Jerry Box, associate creative director, and Frank Newcomer, producer, viewed preliminary motion tests-generally on 35-mm film-on a Silicon Graphics IRIS 1200 real-time color display system. Director Jeffrey Kleiser then added city lights, smoke effects, "salutes," and sound effects to heighten the realism of the action. Computer-generated elements were later optically enhanced by EFX, Unlimited.


Limited energy consumption in multimedia requires very low power circuits. In this paper we focused on leakage current minimization in single static random access memory (SRAM) cell in 90nm complementary metal oxide semiconductor (CMOS) technology. The leakage current mainly consists of sub threshold leakage current and gate leakage current in 90nm CMOS technology. So minimizing the sub threshold leakage current and gate leakage current is most important aspect in low power memory design. This work presents a technique based on dual threshold voltage (Vt), dual gate oxide thickness (tox) and dual power supply (Vdd) assignment together to minimize gate leakage and sub threshold current of SRAM cell.Simulation results using 90nm CMOS technology show that this technique can reduce the total leakage current dissipation of a single SRAM cell by more than 75% with less delay penalty.


(57) Abstract: The purpose of the present invention consists of a catalytically active mixed oxide which is applied on the outer surface of the non-porous carrier and its support of inert, unsaturated C


The invention discloses a display method and a corresponding device used for solving the problem in the prior art that a labeling operation is inconvenient when a protection mode is used for demonstrating. The display method comprises the following steps: projecting an original image on a protective plane by electronic equipment through a projection unit; acquiring at least two image frames including projected images through an image acquisition unit by the electronic equipment; determining a characteristic object in every frame of the at least two image frames by the electronic equipment; determining a characteristic locus on the protective plane by the electronic equipment according to spatial position information of the characteristic object in every frame of the at least two image frames; making the projection unit to project by the electronic equipment in combination with the original image and the characteristic locus, wherein a characteristic tag is displayed at the characteristic locus in a second projected image formed by projection.


The purpose of the research is to develop the method for early diagnosis of real-time traffic loss with time-out control in software defined networks (SDN).Methods. An overview and description of the transfer of heterogeneous traffic in an Ethernet switch with support for quality of service and Time-Triggered Ethernet technology is given. The functioning of the timeout control blocks for instantaneous removal of a frame from the hard timeout control system and depending on the length of the frame when the idle timeout receiving side is reached is described in detail. These control units are included in the hardware guard of control time-outs for real-time traffic. The work of the switch OpenFlow is described using guard of control time-outs. The formation of time windows of timeouts during frame transmission is described and developed.Results. With the help of the proposed method of early diagnosis of real-time traffic losses with control of timeouts in SDN, a modeling of SDN based on Petri nets and using the CPN Tools modeling package was carried out. The obtained model and experimental results are consistent with the theoretical calculations and the proposed method of transmitting real-time traffic, taking into account its losses in SDN.Conclusion. Using the model, the functional and temporal behavior of the model was investigated; the method was verified using Petri nets. The results were obtained in the form of time diagrams reflecting the work on traffic types in accordance with the proposed method.


A multi-chamber container comprising: a hollow outer tank; a hollow inner tank, the tank is placed in the outer tank; a can lid, which seals the top opening of both the outer tank and the inner tank so that the tank a first outer tank forming a closed chamber, the inner and outer tank forming a closed second chamber, along the outer periphery of the can end has a scroll down and formed a circumferential groove across and communicating with the circumferential groove of the opening in the groove, the circumference of can lids tightly gripping the outer circumferential groove first portion of the tank top edge and the top edge of the inner tank, while the inner groove is tightly gripping the top edge of the second portion, and the groove a top edge of said second portion forming a folded-over seam to overlie the top surface of the can end. There method of manufacturing a multi-chamber container.


Range anxiety has become a major stumbling block for the adoption of electric vehicles (EVs) when it comes to long journeys. Aside from the extended charging period, most of the existing charging techniques require EVs to remain stationary while being charged. With the major advance in dynamic wireless charging technology, the Mobile Energy Disseminator (MED) has been introduced as a means to supply energy to an EV on the road. MED can provide energy to the vehicle during its motion without the need for larger batteries or an expensive change in infrastructure. However, MED is often associated with vehicles with predefined travel paths which forces an EV to alter its route to take advantage of the MED charging option. In this paper, we present RIMEC, a -Routing for -Increased Mobile Energy Charging algorithm that determines an optimized EV travel route for utilizing MEDs in order to maximize the amount of potential energy that can be harvested while minimizing the impact on travel time. The experiment results conducted in a realistic simulation scenario indicate that RIMEC not only achieves its design goals but also boosts the system throughput by serving a larger number of EV charging requests.


Let , be regular in the unit disc . G. Szegö [5] and Y. Miki [3] proved that if f(z), given by (1), is univalent (starlike with respect to the origin; convex; close-to-convex in E) then any one of the partial sums , is also univalent (starlike with respect to the origin; convex; close-to-convex) in |z| < ¼and that the constant ¼ cannot be replaced by a larger one.


The influence of 2‐months ingestion of an "immune" nutrient fortified breakfast cereal on immune function and upper respiratory tract infection (URTI) was studied in children during the winter. Subjects included 73 children (N=42 males, N=31 females) ranging in age from 7 to 13 years (9.9±1.7). Subjects were randomized to 1 of 3 groups (double blinded): cereal without added nutrients, or with moderate or high "immune" nutrient fortification (A, C, E, and B‐complex, iron, and zinc, with higher A, C, E in the "high" group). Immune measures included delayed‐typed hypersensitivity, global IgG to pneumococcal vaccination, salivary IgA, PHA‐stimulated lymphocyte proliferation, natural killer cell activity, and granulocyte phagocytosis and oxidative burst activity. Subjects under parental supervision filled in daily logs using URTI symptoms codes. Subjects ingested 3337±106 gm cereal during the 2‐month study, which represented 14% of energy intake and 20–80% of selected vitamins/minerals. Despite elevated intake of nutrients, URTI rates and pre‐ to‐ post‐study changes in all immune measures did not differ between groups. Data from this study indicate that ingestion of breakfast cereal fortified with an "immune" nutrient blend for 2 winter months by healthy children does not influence biomarkers of innate or adaptive immune function or URTI.


In this paper we describe the shifting knowledge logics of two work communities as these two communities try to align with stakeholders in the development and implementation of two different projects. In both cases the display of senses becomes vital in order for the communities to appear as if they align with rationalistic and cognitive learning and sense-making. Observation of and narratives from the informants in the study show, however, how they make use of a wider range of senses. More specifically we describe how these communities use senses and emotions in communicating and further develop the knowledge creating processes, as they worked with story telling and collective reflection that incorporated elements of intuition and gut-feeling. In one of the cases this may represent an obstruction to learning and knowledge creation in practice, while in the other it seems to trigger learning and a shift towards sensing. In both cases we describe how the employees cope with the differences in knowledge logic, and how they develop survival mechanism and problem solving tools in a different vein than the knowledge logic of the stakeholders. The purpose of the paper is further a call for more research and conceptual development of the influence of stakeholder's assumptions on knowledge and learning. 1 Corresponding author: Buskerud University College, Postboks 164 Sentrum, N-3502 Hønefoss, Norway, firstname.lastname@example.com, telephone +47 97021325, fax +47


This article raises the unavoidable need to justify the creation of an office of attention to accessibility and diversity of user, recognizing a new scenario, more diverse and plural, allowing to make proposals and solutions in accordance with the different social contexts to establish priority lines based on the equality of rights and equal opportunities. To meet the objectives of the study has been conducted a descriptive and quantitative analysis on the characteristics of the population of a real case of the province of Granada, redefining the concepts of accessibility and diversity, to take on the multiple needs of the beneficiary population and address the improvement of spaces, products, information and communication technologies, and sustainable services whose value is the process that enhances all areas, by changing attitudes and necessary adaptations based, fundamentally, in the achievement of the maximum functionality and autonomy of the selected population.