Allergic responses are characterized by a biphasie response profile consisting of an immediate reaction to an allergen, followed by a late-phase response. Early allergic reactions are elicited by immunoglobulin E (igE)-mediated activation of polymorphic granulocytes, causing release of inflammatory mediators, which include histamines, prostaglandins, and leukotrienes (37, 50). In response to these inflammatory mediators, lymphocytes, monocytes, basophils, and eosinophils are eventually recruited to airway tissues in what is called the late phase ofthe allergic response (49, 52). It is now well recognized that the allergic state is also influenced by lymphokines, which not only regulate IgE synthesis, but also afl̂ ect the activation and diflerentiation of allergic efl'ector cells (20). This notion is supported by observations from a number of immunotherapy studies in which relief of clinical symptoms has been observed in the face of unchanged allergen-specific IgE levels (11, 12). In addition, successful immunotherapy has been correlated with a decrease in allergen-specific T-cell responses (22). T-cell unresponsiveness has been attributed to T-cell anergy. As a consequence of anergy, certain T-cell lymphokines which are important in propagating the allergic cascade are not produced. Because of these new insights, the emphasis of allergy research has now shifted to elucidating the early events in allergenspecific immune reactions, particularly the mechanism by which T cells control the allergic state.


Summary form only given. To achieve superior video compression performance it is generally necessary to base the encoding decisions on a local scale, instead of the traditional frame-by-frame approach. Partitioning schemes for optimal frame subdivision have been proposed. Unfortunately, a full local approach that leads to inhomogeneous partitioning of the frame encounters the serious problem of dealing with an increase of side information, particularly in the area of very low bit-rate compression where a relatively large overhead can possibly erode the benefits of the local analysis. Our approach adopts a moderate position, which can still retain some of the advantages of variable block size while keeping the overhead to a bare minimum. The idea is to subdivide a frame in a fixed number of square panels that we call "megablocks." All decisions relative to intra (I) or inter (P) coding are made at the megablock level. These decisions pertain to motion block size and degree of error quantization in the P-mode as well as vector and scalar quantization of subbands in the I-mode. The key to the improved performance of the megablock partitioning scheme is the joint cost minimization of motion field and quantized error information. In very low bit rate video coding, the cost of transmitting motion vectors consumes a significant fraction of the total bit budget. The megablock structure permits the use of variable size motion blocks without incurring the cost associated with motion segmentation or a full quadtree approach.


This short paper attempts to provide an updated brief examination of hyperlexia covering on its changing definition, prevalence, signs and symptoms as well as the currently available strategies to help children with hyperlexia. The author has also incorporated the Triple-D model of teaching and the CCAS framework to help paint a clearer picture for educators to navigate through the planning that will support the holistic development of the child with hyperlexia. Consequently, the educator can envision what can be done to help the child see the light at the end of the tunnel and the journey together with the child to see the light can be a fulfilling one.


OVERVIEW Using a matched-pairs sample consisting of 1,358 observations, we investigate the effects of CEO gender on firm-level risk taking and on the risk-performance relationship. The upper echelons literature has argued and found empirical support for the proposition that companies are "reflections" of their corporate leaders. Nevertheless, the influences of CEO gender on firm outcomes like risk taking and performance have yet to be systematically conceptualized and empirically studied. We take a step in this direction by developing competing theories arguing that female CEOs will be less (more) likely to take high risks than male CEOs. When female CEOs do take high risks, however, they will be more likely than males to achieve superior performance. Our findings indicate that overall female CEOs take less risk than their male counterparts, but also corroborate our arguments that high risks by female CEOs will be more effective. Moreover, CEO duality dampens the effect of gender on corporate risk-taking. Overall, our study provides preliminary evidence that, while CEO gender matters, the influences of CEO gender on organizational outcomes are anything but straightforward


Ceramic tiles are one of the most widely used materials in both commercial and residential buildings. As environmental problems increase, the need for environment-friendly building design increases. To achieve this, architects and engineers need reliable data on the environmental impacts of various building materials—including ceramic tiles. This paper reports the results of environmental impact assessment of ceramic tile production in Thailand. Key impact categories, including fossil fuel impact, global warming, ozone depletion, ecotoxicity, and human toxicity were assessed. The results showed that when assessed by EDIP methodology, the global warming impact value of 3.73E+3 kg CO2-eq per megagram (Mg) of ceramic tile is quite prominent and is rather high compared with existing data in current literature. The human toxicity impact value is also significant. The values of the other impact categories were also determined and found to be relatively high. When assessed using the Eco-indicator 99 methodology, the results showed that the fossil fuel category was the most affected with a value of 8.62E+1 Pt per Mg of ceramic tile, followed by respiratory inorganics and climate change. Raw materials transportation stage yielded the highest environmental impact values. It is thought that the key factors responsible for the relatively high impact values are the process technologies employed and the long transportation distances of the raw materials. It was concluded that the environmental impact values of ceramic tile production in this study are different from, and in most cases higher than, the values presented in current literature.


In their attempts to date the ten Shih-ku, or Stone Drums (hereafter SD), which are generally regarded to be the earliest stone monuments unearthed in China to date, Chinese scholars have frequently cited the style of the script in the SD inscriptions as a telling feature of their date (e.g., Yao Ta-jung 1911, Ma Heng 1931, Ch'iang Yün-k'ai 1935, Yang Shou-ch'i 1935, Tai Chün-jen 1952, Na Chih-liang 1958, T'ang Lan 1958, Chang Kuang-yüan 1966, and so forth). Yet their analyses of the script and conclusions have differed considerably, with final assessments differing by as many as 1700 years! The primary reason for this disparity, in my opinion, is that the problem has never been approached systematically. The usual procedure has been to select a handful of graphs from the inscriptions which either point to a very early date for the SD texts or a later date, depending on the author's point of view.


Selected field surveys of migrants and nonmigrants in rural and urban areas are examined in order to define the motives underlying internal migrations, especially those occurring in developing nations. Migration is a function of the absolute real per capita income differentials for each skill level or occupation and is a function of the job availability differentials for each skill level or occupation. Rural-urban migration continues until expected urban real income equals expected rural real income. Cost-of-living adjustments in these field studies should include consideration of payments in kind and imputed housing costs. Governmental migration policies in developing countries, which have to date encouraged migration from rural to urban areas, have led to an increase in urban unemployment. The minimum urban wage for unskilled labor has tended to rise much faster than the minimum or current agricultural wage, and the income differential between urban and rural unskilled workers has been increasing. Public and social service investments have been largely confined to urban areas, and rural communities have been neglected. Demographic and statistical data are included. Numerous references.


This article reviewed the advances in crop drought-tolerant gene engineering, including osmotic regulation, protective enzyme systems, drought-tolerant genes and genetic characteristics of crop drought resistant mechanisms. The study on crop drought tolerance genes is good for understanding of crop drought-tolerant mechanisms, so as to provide some new ideas and new means for China's water-saving agricultural research.


The invention discloses a lithium ion battery ceramic diaphragm coated with polyvinylidene fluoride. The lithium ion battery ceramic diaphragm comprises a base material diaphragm, wherein at least one surface of the base material diaphragm is coated with ceramic slurry; the ceramic diaphragm is prepared by the following steps of mixing and dispersing polyvinylidene fluoride and a dispersing agent at a weight ratio of 1 to 0.1-50 to obtain a dispersion glue solution; mixing and dispersing the dispersion glue solution and ceramic granules at a weight ratio of 1 to 0.1-10 to obtain ceramic slurry; and uniformly coating the surface of the base material diaphragm with the ceramic slurry, and drying the base material diaphragm to obtain the lithium ion battery ceramic diaphragm coated with polyvinylidene fluoride. The surface of the base material diaphragm of the lithium ion battery is coated with the ceramic diaphragm of polyvinylidene fluoride and ceramic granules, wherein the ceramic diaphragm is 0.1-10um in thickness; the ceramic diaphragm is compact in surface and uniform in thickness; polyvinylidene fluoride has a relatively high decomposition temperature, so that the diaphragm can be protected when the surface of the base material diaphragm is coated with the polyvinylidene fluoride; and therefore, the thermal resistance of the diaphragm is improved, so that the safety performance of the lithium ion battery is further improved.


The present situation concerning the developments and use of precast reinforced concrete elements in various types of works, buildings and industrial structures in romania is described, and emphasis is laid on the more important technical and economic aspects of this utilization. /TRRL/


Understanding the cybersecurity threat landscape is critical to mitigating threats, apportioning limited resources, and hosting a resilient, safe, and secure Olympic Games. To support the security goals of Tokyo 2020, this report characterizes the cybersecurity threats that are likely to pose a risk to the games, visualizes a threat actor typology, and presents a series of policy options to guide cybersecurity planning.


Abstract An iterative technique was used to locate some 400 earthquakes, estimate corrections to the Jeffreys-Bullen P travel times and estimate azimuthally dependent station adjustments (station corrections). An oversimplified model for the upper 700 km of the mantle was adopted in order to provide a standard for the investigation of regional variations in travel times. In the estimation procedure only data for epicentral distances in the range 20° to 105° were used, and the data were truncated to remove gross errors. The new P travel times are generally 2 to 3 sec less than those given in the Jeffreys-Bullen Tables.


The mechanism of the cycloaddition reaction forming a bicyclic com- pounds between singlet vinylidene (H2C=C:) and ethylene was investigated using the CCSD(T)//MP2/6-31G  method. From the potential energy profile, it can be predicted that this reaction has one dominant channel. The presented rule of this reaction, a (2+2) cycloaddition reaction between the two reactants occurred forming a four-membered ring carbene (INT1), in which the sp lone electron of the C atom from carbene in INT1 and the π  unoccupied orbital of ethane form the sp→π  donor-acceptor effect, resulting in the formation of intermediate (INT2). Due to the further sp 3 hybridization of C atom from car- bene in INT1, INT2 isomerizes to the bicyclic compound (P2) via the transition state (TS2).


The article highlights studying the efficiency psychopharmacotherapy of remote consequences of combat psychic trauma at veterans of combat actions on the contemporary stage.


The quiescent optical spectrum of the SU UMa-type dwarf nova TY PsA is characterized by broad, doubled emission lines. Cross-correlation radial velocities reveal a periodic modulation at the orbital period of 0.08414 d. This modulation could not be ascribed to variations in the line profile which appeared to be free of s-wave and other V/R variations. Instead, detailed investigation showed radial velocity variations in the entire line profile, indicating that the modulation was due to orbital motion. From previous observations during superoutburst of the broad, shallow absorption lines of TY PsA, no orbital radial velocity variations were detected


Cybersecurity is extremely important nowadays. Many objects, such as banks, airports, big supermarket and gas stations can be under hacker attack every day. Therefore, their internal cybersecurity, that is based on telecommunication network security is so important. There are three main types of system that protects telecommunication networks: firewalls, sandboxes and antivirus programs. Each of them persuades their own purpose and important for cybersecurity. In this paper, they will be discussed from quality management point of view.


Chia ( Salvia hispanica L.) contains the highest level of omega- 3 fatty acid available in any cultivated plant source. The objective of this research was to find out the suitable planting time for chia in Bangladesh and to study the effect of planting time on its growth and yield. An experiment was carried out at the field laboratory of the Department of Crop Botany, Bangladesh Agricultural University (BAU), Mymensingh, during the period from November 2013 to July 2014 to study the growth, morpho-physiological yield contributing characters and yield of chia. The experiment was laid out in a Randomized Complete Block Design (RCBD) with three replications. The collected data were analyzed statistically and the means were adjudged by DMRT using the statistical computer package program, MSTAT _ C. The tallest plant (136 cm), highest number of inflorescence plant –1 (13.67), highest amount of total dry matter (305 g) and highest root length (7.767 cm) were recorded from November planting at harvest. However, leaf area plant –1 (207.2 cm 2 ) and LAI (1.891) had also significantly higher from November planting at 90 days after sowing (DAS) compared to other planting times. November planting further recorded the higher CGR (33.43 g m -2 day -1 ) at the stage between 76–90 DAS and thereafter they decreased. Higher seed yield (1033 Kg ha –1 ), husk yield (888 Kg ha –1 ), seed yield plant -1 (4.773 g), husk yield plant -1 (2.840 g) were also recorded from November planting. In December planting the seed yield, husk yield, seed yield plant -1 , husk yield plant -1 were 681 Kg ha –1 , 340 Kg ha –1 , 2.350g and 0.9467g, respectively. Lower seed yield (159 Kg ha –1 ), husk yield (166 Kg ha –1 ), seed yield plant -1 (0.6150 g) and husk yield plant -1 (0.5383 g) were recorded from January planting. Except total dry matter, other morpho-physiological characters, yield and yield contributing factors were less effective in January than other planting time. February and March planting did not produce any fertile spike resulting yield less vegetative growth. These results revealed that, November planting was found outstanding superiority for plant growth, yield and morpho-physiological characters of chia in Bangladesh. Asian J. Med. Biol. Res. December 2015, 1(3): 502-507


Hough transform is a primary way to detect straight line,but the hough transform has some problems about the accuracy and efficiency.In this paper,we present a method for detecting the building edge lines and perform an experiment on DSM.The method we describe in this paper absorbs the "voting procedure" in hough transform.After getting the edge using sobel operator,and labeling the edge of all buildings.Then identify straight lines of the labeled edge separately.We label the objects and get the edge points' coordinates in sequence.Because two points can determine a line,so if the endpoints are known,we can get the line's slope and the line can be determined by the obliquity which extracted from the voted accumulator.Experimental results indicate that the approach can detect the straight line segment precisely and simply.


The outcome-based education (OBE) philosophy emphasizes "student-oriented, result-oriented, continuous improvement". Based on the practical teaching practice of the core course "Data Structure and Algorithm" for engineering majors of application undergraduate, it is proposed that the OBE education concept should be integrated into the practical teaching system reform of "Data Structure and Algorithm". The reform ways of the preparatory process of practical teaching are analyzed from four aspects: talent training plan, practical teaching syllabus, practical teaching faculty, and practical teaching textbooks. The reform strategies of "four characteristics" in the implementation of practical teaching focus on: building "open" laboratory, strengthening "comprehensive and designed" experiment, and promoting "innovation" by competition. The reform measures of practice teaching assessment are explored from two perspectives: practice teaching assessment mode, and assessment result analysis. The purpose is to strengthen the training of students' basic skills, application abilities and comprehensive qualities, so as to achieve a seamless connection between the quality of talent training and the needs of engineering applications. The reform of the practical teaching system of similar courses in related institutes can be used for reference.


The invention discloses a sludge organic fertilizer for red soil and a preparation method thereof. The organic fertilizer is prepared by fermenting sludge, comprising the following steps: A, regulating the sludge to allow the moisture content to be 55-65 %, C/N value to be 27-33, and the total organic carbon to be 35-45 %; B, first fermented manure: after uniformly stirring, putting the stirred sludge into a fermention device to establish a fermentation pile, heating, and carrying out fermentation for 65-75 h at the fermentation temperature of 52-57 DEG C and under the condition of the pH value of 9-11; and C, second fermented manure: carrying out fermentation for 55-75 h at the fermentation temperature of 58-63 DEG C and under the condition of the pH value of 7-9. According to the invention, the organic fertilizer is prepared by using two-step aerobic composting, the composting time of 30-40 days of the traditional windrow sludge composting technology is reduced to 110-160 h, the fermentation period is shortened, the composting efficiency is greatly increased, and the processing capability capacity of sludge is improved. The invention is suitable for rapid composting of alkaline coagulant used in small and medium-sized sludge factories and livestock farms and the like, especially for processing alkaline sludge. The prepared organic fertilizer is slightly alkalescent and suitable for slightly acidic soil, and has good effect on pitaya growing on red soil.


Objective To study the clinical efficacy of combined endoscopic metal stent and radiotherapy in advanced esophageal carcinomas.Methods Fortynine cases with advanced esophageal carcinoma were treated with endoscopic stent implantation alone(n=24) and combined endoscopic stenting and radiotherapy(n=25).The rate of survival,clinical symptom alliviation and morbidity of the two group were compared. Results There was no difference in alliviation of dysphagia and morbidity rates between the stent alone and combined treatment group. The survival rates of 9 and 12 months in patients treated with combined therapy were significantly higher than those in patients alone with stent implantation.Conclusion Endoscopic metal stenting in combination with radiotherapy is a feasible and practical management in advanced esophageal carcinoma,its efficacy is superior over the stent implantation alone. Thus it is worth to expand the clinical application of the combined therapy.


Using the Harrison's bond orbital model for the IV group 3D and 2D com-pounds analytical expressions of the high- and low-frequency dielectric suscepti-bilities and dielectric constants, linear electrooptical coefficient, photoelastic con-stants and pressure dependences of the dielectric constants are obtained.


This paper presents an overview of our research on the preparation of monolithic and composite non-oxide ceramic foams derived from polymeric precursors. Two new methods to product ceramic foams from polymeric precursors were developed. Firstly, synthesis of silicon carbide (SiC) foams as a product of direct pyrolysis of polysilane precursors and, secondly, preparation of SiC and silicon carbide-silicon nitride (SiC-Si 3 N 4 ) composite foams using polymeric precursor solutions are described. The features of the ceramic foams produced were dependent on the compositions and the structures of the precursors. In the case of direct pyrolysis, the best SiC foams were produced using precursors with pyrolytic yields between 50-60 wt%. Ceramic foams produced by the polymeric precursor solution method have well-defined open-cell structures with the strut cross-sections free of macro-voids.


The importance of developing Submarine Weapon System rapidly is discussed and the shortcomings of the existing simulation environments for supporting its development are presented. To meet the requirements of developing Submarine Weapon System, a new simulation system of Submarine Weapon System based upon mathematical simulation has been established, which supports hardware-in-the-loop simulation test, and then the structure and characteristics of the simulation system, the key technologies such as propagation loss calculating in sonar simulation modeling, torpedo trajectory design and its control and guide modeling, the design and integration of the simulation system are described in detail. Finally, the application of the simulation system is introduced and its future application prospect is given.


Power electron device plays an important role in the development of inverter.A self switch off and intelligent device used in the power electron device have been produced.The inverter consisting of power electron device is economical,safe,fast,small in volume and high accurate.The inverter in this system consists of IGBT.The SPWM is adopted.This paper introduces the basic structure of three phase SPWM inverter and the desigh of the prime circuit,parallel buffer and drive circuit.The results show that the adjustment of the system is facile and its performance is of high quality.


The morphological diversity of 61 varieties of sweet potato(including 27 improved varieties and 34 landraces) from Hunan and other areas were analyzed by cluster analysis method;the degree of genetic variation of sweet potato landraces in Hunan and the genetic differences between it and improved varieties were discussed,and the application value of genetic variability of sweet potato was evaluated.The results showed that the average genetic distance between landraces in Hunan was 2.596 0;the average genetic distance between improved varieties in Hunan was 2.839 4;the average genetic distance between landraces and improved varieties in Hunan was 2.547 2;the highest average genetic distance was between landraces from Hunan and Guangdong with 3.002 0;the highest genetic distance was between improved varieties from Hunan and Ximeng No.1 from Brazil with 3.547 3.


The role of digital innovations to support the United Nations Sustainable Development Goals (SDGs) has been widely recognized in major recent publications such as the Cisco-ITU report on IoTs and the Ericsson-Columbia study of ICT4SDGs. These and other studies have identified short range and long range challenges that must be addressed. This paper introduces a computer aided planning, engineering and management environment that has been developed to address these challenges for rapid progress in health, education, public safety, public welfare, and other vital areas. This environment, currently operational for a UN Partnership, consists of a set of intelligent advisors that collaborate with each other in a fashion similar to a team of consultants who guide the user through an extensive array of choices throughout the learn-plan-do-check cycle. The intelligent advisors quickly produce highly customized plans for SDG services for different countries by integrating diverse techniques such as semantic web, Big Data, deep learning, enterprise ontologies, business patterns, and gamification. This paper emphasizes the practical and innovative applications of computer aided strategic planning for SDGs and other global efforts in smart cities and next generation enterprises. Experiences and insights gained in development, deployment, maintenance and methodologies for actual use of computer aided planning systems are highlighted.nbspnbsp


Summary Lymphoid neoplasms represent a heterogeneous group of neoplasms, including non-Hodgkin lymphoma, Hodgkin lymphoma, multiple myeloma and acute and chronic lymphocytic leukemia. Burkitt lymphoma is a highly aggressive neoplasm of mature B cells in non-Hodgkin lymphomas. Stomach involvement occurs in only 10% of patients. Almost all cases are detected in the late stages as a bulky mass located in the abdomen or other gastrointestinal sites. In this report, we describe a 72-year-old female diagnosed with BL of the stomach.


varied classical learning is shown in a short but entertaining and suggestive paper by Professor Marrou on 'Humanisme et Christianisme chez Clement d'Alexandrie d'apres le Pedagogue'. In Clement's view, as the late Edwyn Bevan remarked, philosophy had filled the role for the Greeks that the Law had filled for the Jews, of being the tutor that led the way to Christ, and Professor Marrou cites many passages where Clement supports a proposition by parallel quotations from Holy Scripture and the pagan classics. In Mr. Walzer's account of 'Platonism in Islamic Philosophy', with which the book ends, we see more clearly than ever how much that lies outside the usual scope of classical studies is relevant to classical texts and problems. Early Muslims, like early Christians, saw in Platonism a theistic philosophy which could provide them with the metaphysical basis of which their theology stood in need. Platonic scholars will be especially interested in Walzer's account of the doctrines of Al-Farabi, who developed from Plato's Republic a blue-print for an ideal Muslim community governed by a philosopher-Caliph. The Muslim philosophers in general shared with the later Greek Neoplatonists the view that Aristotle was and remained essentially a Platonist. Here, as throughout these studies, one is conscious of the difference of aim and viewpoint between a modern historically minded scholar and those Neoplatonic thinkers for whom the classics were a repository of true doctrine as well as the subjectmatter of academic research.


their behaviour as substrates may be fortuitous because the number of samples was not large and their small amounts did not permit their thorough analysis. The kinetic treatment is empirical. No simple theoretical interpretation is possible, first, because the polymeric substrate is likely to be susceptible to enzymic attack at a large number of sites and, secondly because the effect of the products of this reaction upon the formation of turbidity is not known. However, under suitable conditions, useful comparisons of enzymic activities can be made.


Objective To assess differential diagnostic value of MSCT with multi-planar reconstructions(MPR)in the rare intra-trachea and main bronchial tumor.Methods MPR images of 23 patients including intra-tracheobronchial benign tumor(n=16),and intra-tracheobronchial malignant tumor(n=7)were retrospectively analyzed.All the final diagnosis was proved by pathology.The chest images were viewed by two separate radiologists.Thickness of tumor involved trachea and main bronchial adjacent wall was measured.Results Sixteen patients with benign intra-tracheobronchial tumor revealed without the thickening wall of main bronchus,among them,the margin of 13 tumors were smooth and of the rest 3 were rough,the mean tracheobronchial wall thickness was 2.45 mm.Seven patients with malignant intra-tracheobronchial tumor revealed the thickening wall of bronchus,and their margins were rough with the mean tracheobronchial wall thickness 5.83 mm.Conclusion MSCT with MPR can display the size,morphology,range of intra-tracheobronchial tumor and its relation with tracheobronchial wall and is helpful to the differential diagnosis of intra-tracheobronchial tumor.


This paper provides a characterization of the classical Charnes, Cooper and Rhodes' (CCR) model in Data Envelopment Analysis (DEA). The characterization is based on the Weak Axiom of Profit Maximization (WAPM) in Firm Theory. Efficiency measures for Decision Making Units (DMUs) provided by the classical CCR-DEA model are derived as measurements of deviations from the conditions prescribed by the Weak Axiom of Profit Maximization (WAPM).


EDITOR—I welcome the informative clinical review on common skin infections in children by Sladden and Johnston.1 However, when a Molluscum contagiosum arises in eyelid …


Refraction of light at the interface of two materials occurs if they have different refractive indices (RI). Therefore, it is theoretically possible to produce bright, transparent, glassreinforced polymers by matching the materials' RI. This largely depends, among other factors, on the wavelength of the incident light (dispersion) and on the temperature of the material (thermo-optic coefficient), whereby the RI of polymers in the visual range increases with decreasing wavelength and temperature1,2 and the refractive index of glass also decreases with the wavelength but usually increases with increasing temperatures3. Whereas the dispersion of transparent polymers and optical glass may be identical, the thermooptic coefficient ∆nrel/∆T of glass has a value between -5.4 and 32.2x 10-6/K 4. Polymers have a negative thermo-optic coefficient, which is nearly two orders of magnitude higher5. These facts lead to a wavelength-dependent and at least temperature-dependent transmission of the aforementioned composites6.


Educational timetabling has long piqued the interest of the scheduling community. Since timetabling governs how universities operate daily, it has been vital in academia to put substantial effort into creating schedules of the highest caliber. To create schedules that satisfy all stakeholders, various approaches have been tried to solve educational timetabling problems, which are typically NP-Hard. Over the past 20 years, several scheduling contests have been held with a focus on issues related to educational operations. In this paper, we focus on the Post Enrollment Course Timetabling Problem and two datasets from the International Timetabling Competitions held in 2002 and 2007. We propose a local search procedure augmented by a base mathematical model and variations of this model that yields competitive results, within reasonable execution times, to some of the best-known solutions.


MAXWELL, ANDREW CHARLES. A Teaching Job Shop Control System With Real-Time Inventory Management. (Under the direction of Dr. Robert E. Young.) This thesis presents a teaching job shop control system for running in assembly laboratories at colleges and universities in preparing Industrial Engineering students for challenges faced in real-world factories. Current techniques fail to encompass this idea of training for students like the proposed method does. Microsoft Access was used in creating a database that is the center point in this new system. Inventory is managed using this database system and added if parts are created in the manufacturing lab and moved to the assembly area. The system will stop if parts are low until new parts are created. In this new system, a pallet with an unfinished product on it moves down a conveyor system until it reaches the next workstation. At this station, the station operator scans a barcode on the pallet. This barcode contains what product is on this pallet. Based on this information, an ordered list of tasks appears on the workstation computer screen and must be done before the pallet can be moved on. When all tasks have been completed at a station, the station operator clicks "done" on the screen and then can either move to the next pallet or end the run. Statistics are kept on the quality of the final products and parts as well as on work-in-process and on a goal percentage of good products out at the end of a one-hour time frame. Administrators will be able to assign tasks and parts to products and stations, as well as be able to assign the goal


A long-term field experiment has been studied for more than 90 years on the testing ground of the University of Agricultural Sciences, Vienna, situated in Grosenzersdort: Lower Austria, The effects ofmonoculture versus crop rotation and different fertilizers farmyard manure, mineral fertilizer, no fertilizer on the yield of spring barley (Hordeum vulgare), winter rye (Secale cereale) and on soil parameters was investigated. For results of these long-term experiments see STEINECK and RUCKENBAUER (1976). As no biological data existed, we used the bait-laminatest, as developed by VONTORNE (1990a, b), to assess the biological activity; and in addition, we determined the abundance of potworms (Oligochaeta,· Enchytraeidae) as potential feeders on the baitsubstances (PFEIFF et al., 1998). The bait-lamina-test is a possibility for measuring biological activity, which can be disturbed in the eomplex soll ecosystern, Organie matter is exposed in the upper layer of the soil and its reduction in time is determined. Soil organisms are artracred by the exposed bait substance and feed on it, Theevaluation of the feeding activity on the bait is done by a simple yes/no classification. The bait-lamina-test has already been used several times as a screening test for ecological monitoring (HOFFMANN et al., 1991; KRATZ et al., 1992; LARINK and LOBBEN; 1990; lARINK, 1993). Forty to ninety percenr ofthe organie matter in the soil is decomposed by biotic processes, whereas the contribution of abiotic degradation is 5-30 %. Soil mesoand maerofauna mainly reduce plant residues to small pieces, thereby expanding the surface area and breaking up complex components. At this stage, organic matter can be more easily reduced by micro-organisms, whose population dynamics are affected by the soil fauna. Through the activity of soil organisms, the plant residues are on the one hand transformed into humic substances and on the other hand mineralized into inorganic matter which is returned into the nutrient cyele (ErSENBElS, 1993). SoiI micro-organisms and fauna in arable fields. where natural cycles are interrupted, are strongly affected by intensive soil management and fertilization. The micro-climate is changed, soil porosity is gready reduced, many soil animal species are eradicated, and micro-organisms may show enhanced activity (EHRNSBERGER, 1993). To assess the


In this paper we develop and study numerically a model to describe some aspects of sound propagation in the human lung, considered as a deformable and viscoelastic porous medium (the parenchyma) with millions of alveoli filled with air. Transmission of sound through the lung above 1 kHz is known to be highly frequency-dependent. We pursue the key idea that the viscoelastic parenchyma structure is highly heterogeneous on the small scale ε and use two-scale homogenization techniques to derive effective acoustic equations for asymptotically small ε. This process turns out to introduce new memory effects. The effective material parameters are determined from the solution of frequency-dependent micro-structure cell problems. We propose a numerical approach to investigate the sound propagation in the homogenized parenchyma using a Discontinuous Galerkin formulation. Numerical examples are presented. Understanding the acoustic properties of the lungs is of great interest in a range of medical domains, from the diagnostic of pathologies such as bronchitis and asthma to recently introduced imaging methods of breathing sounds. Medical doctors have been commonly using the analysis of lung sounds for the diagnostic of pathologies, mainly relying on the stethoscope, and have a good empirical understanding of the relationship between the characteristics of lung sounds and underlying pathologies. However, far less is known about the detailed physical mechanisms of sound generation and transmission in the respiratory system. More advanced models could also explain lung contusions due to a blunt, high-velocity impact to the chest as well as exposure to explosions or, for small mammals, to medical ultrasound. There is extensive experimental data, both in vitro and in vivo, and a relatively good theoretical understanding of the propagation through lung tissue of relatively low-frequency sound, in the audible range. In the frequency band between roughly a few Hz to 1 kHz, the two main components of the lung tissue, air and connective tissue, are acoustically strongly coupled and the resulting mixture behaves like a homogeneous material with high


The utility of pulmonary function testing (PFT) to detect bleomycin‐induced pneumonitis is controversial. We describe its impact on bleomycin dosing in a phase 2 trial of accelerated BEP (bleomycin, etoposide, cisplatin) for advanced germ cell tumours.


We have proposed the use of surface plasmon resonances at the interface of hybrid magneto-photonic heterostructures [Opt. Mat. Exp., 7, 4316 (2017)] for all-optical control of the macroscopic spin orientation in nanostructures in fs time scales. This requires strong spin-photon coupling for the resonant enhancement of opto-magnetic fields, generated through the inverse Faraday effect, in magnetic nanostructures with perpendicular anisotropy. Here we report on the development of nm thick interlayers to control the growth orientation of hcp-Co alloys grown on refractory plasmonic materials to align the magnetic axis out-of-plane, thereby meeting key requirements for the realization of ultrafast magneto-photonic devices.


By applying the methods of the literature review,mathematical statistics and the comparison,this paper comparatively analyzes the management condition of the public and the corporative sport facility of different nature through part of the financial index.The research result shows that the public sport facility be lower than the corporative on the ratio of the self-financing,the asset-liability ratio,the management efficiency,the economic effect and the burden of the tax and fee,the public sport facility is higher than the corporative on the average personnel cost and the employee,and the income based on the sports become the main source of the operational income.The main purpose of this paper is to offer the theoretical support and reference for the management and the reform of the sport facility in China.


Proteasome Activator 28γ (PA28γ) is a member of the 11S family of proteasomal regulators that is constitutively expressed in the nucleus and is implicated in certain cancers, lupus, rheumatoid arthritis, and Poly-glutamine neurodegenerative diseases. However, how PA28γ functions in protein degradation remains unclear. Though PA28γ's mechanism has been investigated for some time, many alternative hypotheses have not been tested: e.g. 1) substrate selection, 2) allosteric upregulation of the Trypsin-like catalytic site, 3) allosteric inhibition of the Chymotrypsin- and Caspase-like catalytic sites, 4) conversion of the Chymotrypsin- or Caspase-like sites to new Trypsin-like catalytic sites, and 5) gate-opening in combination with these. The purpose of this study was to conclusively determine how PA28γ regulates proteasome function. Here, we rigorously and definitively show that PA28γ uses an allosteric mechanism to upregulate the proteolytic activity of the 20S proteasome's Trypsin-like catalytic site. Using a constitutively open channel proteasome, we were able to dissociate gating affects from catalytic affects demonstrating that the PA28γ-increases the affinity (Km) and Vmax for Trypsin-like peptide substrates. Mutagenesis of PA28γ also reveals that it does not select for (i.e. filter) peptide substrates, and does not change the specificity of the other active sites to trypsin-like. Further, using Cryo-EM we were able to visualize the C7 symmetric PA28γ-20S proteasome complex at 4.4Å validating it's expected 11S-like quaternary structure and proteasome binding mode. The results of this study provide unambiguous evidence that PA28γ functions by allosterically upregulating the T-L like site in the 20S proteasome. Significance Statement This study rigorously demonstrates that PA28g allosterically activates the b-2 proteolytic site of the 20S proteasome directly without affecting 20S gating. Further, we generated the first human 11S-human 20S proteasome cryo-EM structure of the PA28g-20S complex showing that, despite it's different affects on 20S activity, it has a similar quaternary structure as the other 11S family members. The significance of these findings is paramount as the b-2 site is responsible for post-basic cleavage and suggests that PA28g is specialized to degrade positively charged DNA binding proteins. Further, b-2 upregulation via PA28g could provide a protective effect against poly-glutamine expanded proteins, like Huntingtin. This work provides a framework for PA28g drug development to treat PA28g addicted cancers and Huntington's Disease.


Title A leukemogenic kinase, FIP1L1-PDGFRA, and a SUMO E3 ligase, PIAS1, form a positive crosstalk via their enzymatic activities [an abstract of dissertation and a summary of dissertation review] Author(s) 井端, 淳 Citation 北海道大学. 博士(医学) 甲第12530号 Issue Date 2017-03-23 Doc URL http://hdl.handle.net/2115/65866 Rights(URL) http://creativecommons.org/licenses/by-nc-sa/2.1/jp/ Type theses (doctoral abstract and summary of review) Note 配架番号:2271 Additional Information There are other files related to this item in HUSCAP. Check the above URL. File Information Makoto_Ibata_abstract.pdf (論文内容の要旨)


Energy storage device is an important component to facilitate microgrid (MG) stable and efficient operation and has great prospect in the future power system. This paper mainly dose two contributions with regard to the grid-connected MG. Firstly, charging strategy for lithium batteries is modeled based on which the economic dispatch model of MG is developed. Secondly, depreciation cost of lithium batteries is added to the cost function of the proposed economic dispatch model. The proposed dispatch model is demonstrated to be successful to achieve the optimal management of the lithium battery. This study is favorable to prolong the cycle life, achieves sufficient utilization of the lithium battery, and provides a theoretical basis for charging process management and optimal DOD dispatch of the lithium battery storage in MG.


Abstract In order to determine the microbial stability of sourdoughs, two bakery sourdoughs made from conventionally and organically grown rye, produced on a large production scale under defined conditions, were studied at regular intervals over a period of 7 months. The sourdoughs contained lactic acid bacteria at levels of 8·43–9·14 log 10 cfu g −1 and yeasts at levels of 6·00–8·04 log 10 cfu g −1 . The number of lactic acid bacteria seemed to increase and the number of yeast to decrease with increasing fermentation time. Four types (A–D) of lactic acid bacteria dominated in both sourdough systems. Their frequencies varied during the sampling period, but seemed to follow the same trend in both systems. Identification based on API 50CH assimilation profiles, classical identification methods and 16S ribosomal DNA sequencing showed that the lactic acid bacteria contained in the two sourdough systems not clearly belonged to any known species of the genus Lactobacillus. Saccharomyces cerevisiae was the only yeast species isolated from the sourdoughs, represented by different phenotypes. In the conventional sourdough system one phenotype dominated throughout the sampling period. In the organic sourdough the phenotype changed after 3 months.


Blum's experiments with albino mice demonstrate a wide variation in the resistance of individual subjects to the carcinogenic effect of ultraviolet light. From clinical experience humans are thought to show the same wide variation in resistance and this paper is a discussion of some of the possible reasons for this variation.


Facing significant change and some challenging targets in her department, Kayleigh Greenacre stuck to six key management strategies to help her team achieve success


A Space-Time Turbo Bayesian Compressed Sensing (STTBCS) algorithm is proposed for Ultra-Wideband (UWB) systems in this paper. Based on the sparsity of UWB signals, the STTBCS algorithm provides an efficient approach for integrating spatial and temporal redundancies. A space-time structure is also designed for exploiting and transferring the spatial and temporal \emph{a priori} information for signal reconstructions in the framework of Bayesian Compressed Sensing (BCS). Simulation results using experimental UWB echo signals demonstrate that our STTBCS algorithm achieves good performance for UWB systems, compared with the traditional BCS and multitask BCS algorithms.


Mobile devices are almost omnipresent in our lives and pervasive or ubiquitous systems are becoming increasingly popular. Context-aware systems offer great potential for increasing notably certain system quality aspects (i.e.: usability, effectiveness, etc.) by gathering context data and adapting systems behavior accordingly. These systems should satisfy a variety of requirements to deal with context in a successful way, including the Separation of Concerns (SoC), as well as those requirements that should be supported by the software architecture. This work analyses different well-known architectural approaches used in the design of context-aware systems, identifies their common aspects, and presents a new proposal based on them. The resulting framework provides a higher SoC degree than the approaches analyzed.


The thermodynamic compatibility of isoprene (SKI) and butadiene (SKD) rubbers in solutions and blends was studied by the methods of cloud points, refractometry, and static sorption within a wide temperature range. It was disclosed that the upper critical solution temperature is equal to 353 K for the SKI-3-SKD system. The SKI-3 and SKD solutions in a mixed solvent toluene-ethyl acetate (1: 4) segregate both upon heating and cooling. It was established that the calculated interaction parameters of the rubbers are larger than their critical values, thus testifying to the incompatibility of these polymers in blends (at T 433 K).


Lots of papers of periodicals concentrate on discussing the pessimistic fatalism of Hardy. Few concerns about farmers' issues in Hardy's novels. This paper explores the farmers' issues in Hardy novels in three aspects.


The JASPER Experiment had been conducted to obtain useful information on FBR shielding analysis accuracy. Results obtained from the post-experimental analyses are summarized in this paper. Both characteristics for bulk shielding attenuation and streaming of neutron through configurations consisting of several materials including B4C, stainless steel, sodium and etc. were clarified and the analysis accuracy confirmed. The shielding analysis system for fast reactors has been improved and verified. These experimental data and analytical results were reviewed from a viewpoint of the applicability to the shielding design analysis of the DFBR. Useful information to be utilized in the design study of the DFBR is accumulated through those activities.


Background Malnutrition affects 20‐50% of patients in acute care hospitals. It is a problem that often goes unrecognized and untreated despite being associated with a number of adverse health consequences. Lack of mealtime assistance has been suggested as a barrier to adequate nutritional intake in patients. Mealtime intervention strategies focusing on the mealtime environment or the provision of support have been promoted by various organizations as a means to improve nutritional intake. Objectives To identify, assess and synthesize available evidence on the effectiveness of mealtime interventions to improve nutritional intake of adult patients in the acute care setting. Inclusion criteria Types of participants Adult and/or elderly patients, aged 18 years and over, from any ethnic background, who were inpatients in acute care hospitals, with any diagnosis. Patients in intensive care or high dependency units, those obtaining their nutrition exclusively by enteral or parenteral means, those receiving palliative care or considered to be at end of life were excluded. Types of intervention Supportive mealtime practices that promote optimal eating and feeding that are not solely related to the actual food or fluid offered or ordered, for or by the patient. Types of studies Randomized control trials and quasi‐experimental studies. Types of outcomes The primary outcomes of interest were measures of nutritional intake namely energy and protein and/or nutritional status, length of stay in hospital and all‐cause mortality. Search strategy A three‐step search strategy was used to find published and unpublished studies reported in the English language. Methodological quality Studies that met the inclusion criteria were critically appraised by two reviewers for methodological validity using the Joanna Briggs Institute Meta Analysis Statistics Assessment and Review Instrument. Data collection Data were extracted from the included studies by the primary reviewer using the Joanna Briggs Institute Meta Analysis Statistics Assessment and Review Instrument. Data synthesis Heterogeneity in study designs, interventions, outcomes and reporting meant meta‐analysis was not possible. The findings were therefore presented as a narrative summary. Results Six included studies involving 1071 patients evaluated the effectiveness of employed assistants, trained volunteers and eating at a table or in a dining room rather than by the bedside or in bed. Patient energy intake increased when employed assistants provided mealtime assistance; however this was only statistically significant for one of the two studies. Energy intake increased when trained volunteers supported patients at mealtimes; however this was only statistically significant in one of two relevant studies. Protein intake significantly increased in the studies where trained volunteers provided mealtime assistance. Energy intake significantly increased when patients ate at a table or in a dining room as compared with eating by their bedside or in bed. Conclusions Few studies were located indicating that there is currently only a small amount of evidence to support the aforementioned mealtime interventions. Furthermore the evidence is of moderate quality providing scope for future primary research.


E. C. Zeeman [2] described the behaviour of the iterates of the difference equation xn+1 = R(xn, xn−1, . . . , xn−k)/Q(xn, xn−1, . . . , xn−k), n ≥ k, R,Q polynomials in the case k = 1, Q = xn−1 and R = xn + α, x1, x2 positive, α nonnegative. We generalize his results as well as those of Beukers and Cushman on the existence of an invariant measure in the case when R,Q are affine and k = 1. We prove that the totally invariant set remains residual when the coefficients vary.


A description is provided of a program developed at Moraine Valley Community College (MVCC), in Illinois, for ,roviding word processing instruction in the library, including recommendations for program development based on MVCC experience and results from a survey of program participants. The first part of the paper discusses a model development process based on the steps used at MVCC to develop their word processing instruction program. First, instructional objectives were es'lablished for the program workshops, including instruction in keyboard function keys, formatting diskettes, and using a spell checking program. Next, an adequate word processing program was chosen and six workshops were scheduled at different day and evening times throughout the semester. Student newspapers, staff newsletters, memos, and posters were used to publicize the workshops and an enrollment form was prepared to avoid overenrollment. Last, effective teaching methods were chosen, including team teaching and awarding certificates of completion. Appendix I provides the instructional guide to MVCC's library microcomputer workshops, covering the following topics: (1) logging-in to the computer network; (2) formatting a data disk; (3) starting the program; (4) practicing with a text; (5) saving files; (6) exiting the program; (7) retrieving documents and files; (8) editing files; (9) using the program dictionary; and (10) printing. Finally, Appendix II presents results from a spring 1992 study of 33 workshop participants. Findings, based on 19 usable responses, indicated that 84% thought the workshop was well paced, while 68% had used the software at least once after the workshop. The document also includes comments to open-ended questions. (BCY) *********************************************************************** Reproductions supplied by EDRS are the best that can be made from the original document. *********************************************************************** TEACHING WORD PROCESSING IN THE LIBRARY By Elizabeth A. Teo and Sylvia M. Jenkins Moraine Valley Community College Robert E. Turner Learning Resources Center 10900 S. 88th Avenue Palos Hills, IL 60465 -PERMISSION 70 REPRODUCE THIS MATERIAL HAS BEEN GRANTED 13Y E. A. Tao S. M. Jenkins TO THE EDUCATIONAL RESOURCES INFORMATION CENTER (ERIC11993 U.S. DEPARTMENT OF EDUCATION 0Mce of Educatana, Research and improvement EDUCATIONAL RESOURCES INFORMATION CENTER IERICI This document has been reproduced as received from the person or organaanon ongina..ng C Mmor changes have been made to improve reproduction dually Pows of view or opmuons stated m this document do not necessaroy represent off.c,a1 OERI position or policy


One of the postulated effects of proand prebiotics is their beneficial influence on mineral absorption from a diet. In the present study, calcium absorption from diets containing white cheese with the potentially probiotic Lactobacillus plantarum strain with a prebiotic addition such as inulin HPX (high performance for high temperature processes) and maltodextrin was investigated. 2.5% of each prebiotic was added to the cheese preparation. The bioavailability of minerals was expressed as apparent absorption and retention indexes. The highest calcium absorption (mg 5 day ) was noted in group receiving probiotic -1 cheese, however there was no significant difference between this and the group receiving control diet without proand prebiotics. Maltodextrin addition to the diet caused a negative effect on Ca balance. Both, apparent absorption (%, mg 5 days ) and retention (mg 5 days ) indexes in this group were significantly lower (P < -1 -1 0.05) compared to other groups. The apparent retention (mg 5 days ) of calcium was significantly higher (P -1 < 0.05) in rats receiving probiotic cheese. Feeding rats with probiotic cheese, containing Lactobacillus plantarum strain, resulted in increased calcium retention compared to control and synbiotic diets.


This paper provides several observations on the impact of employment-based government mandates on job characteristics, wages, and employment. Special attention is devoted to evaluating the effects of mandated health insurance because health care is the largest government mandate potentially on the horizon. In some situations, mandates may be useful to solve adverse selection problems, and to compel firms to internalize the social costs, of production. Moreover, in a world with pre-existing distortions, mandates may reduce other inefficiencies. However, it is concluded that in many situations the optimal way for a government to assure that services are provided is probably not through employment-based mandates. In many situations, mandates are utilized because alternative schemes are politically infeasible. Nevertheless, since the labor supply curve is widely believed to be fairly inelastic, in the long run employers' costs of meeting government mandates are likely to be shifted to employees in the form of lower wages. Cost shifting to employees is expected to moderate the reduction in jobs due to government mandates.


AIMS
Organophosphorus pesticide poisoning occurs frequently in China and can be diagnosed easily based on the history of ingestion and the cholinergic toxic syndrome. Yet, when combined with other toxins, organophosphorus poisoning may appear different.

METHODS
Here, we present a case of acute ethanol poisoning together with a dermal organophosphorus exposure.

RESULTS
Based on the history and a misinterpretation of the physical examination, the patient was treated as an organophosphorus poisoning. Ultimately, serum analysis helped clarify the diagnosis.

CONCLUSIONS
Toxicologist should be aware of the error known as anchoring and take appropriate precautions to limit its occurrence.


This report documents an engineering-scale demonstration with non-radioactive simulants that was performed at SRNL using the Scaled Continuous Processing Facility (SCPF) to fill an 8.5 ft container with simulated Cast Stone grout. The Cast Stone formulation was chosen from the previous screening tests. Legacy salt solution from previous Hanford salt waste testing was adjusted to correspond to the average composition generated from the Hanford Tank Waste Operation Simulator (HTWOS). The dry blend materials, ordinary portland cement (OPC), Class F fly ash, and ground granulated blast furnace slag (GGBFS or BFS), were obtained from Lafarge North America in Pasco, WA. Over three days, the SCPF was used to fill a 1600 gallon container, staged outside the facility, with simulated Cast Stone grout. The container, staged outside the building approximately 60 ft from the SCPF, was instrumented with x-, y-, and z-axis thermocouples to monitor curing temperature. The container was also fitted with two formed core sampling vials. For the operation, the targeted grout production rate was 1.5 gpm. This required a salt solution flow rate of approximately 1 gpm and a premix feed rate of approximately 580 lb/h. During the final day of operation, the dry feed rate was increased tomore » evaluate the ability of the system to handle increased throughput. Although non-steady state operational periods created free surface liquids, no bleed water was observed either before or after operations. The final surface slope at a fill height of 39.5 inches was 1-1.5 inches across the 8.5 foot diameter container, highest at the final fill point and lowest diametrically opposed to the fill point. During processing, grout was collected in cylindrical containers from both the mixer discharge and the discharge into the container. These samples were stored in a humid environment either in a closed box proximal to the container or inside the laboratory. Additional samples collected at these sampling points were analyzed for rheological properties and density. Both the rheological properties (plastic viscosity and yield strength) and density were consistent with previous and later SCPF runs.« less


In a recent article that appeared in Internal Medicine Journal , Cregan argued that there are substantial ethical problems associated with embryonic stem cell technology. 1 The core of Cregan's argument is that, somehow, accepting the use of therapeutic cloning would 'fundamentally [alter] the way we see ourselves and the way we see each other', and would '[distance] us from faceto-face, embodied relations'. This assertion ignores the reality that there are already multiple possible outcomes following the fusion of an egg and sperm, and that people are nonetheless entirely capable of mentally separating these and relating to one another as human beings. At present, some possible outcomes include spontaneous miscarriage or stillbirth, development of a hydatidiform mole, live birth of a baby, creation and subsequent destruction of an embryo as the by-product of the IVF process, and termination of pregnancy. Adding another possible outcome (the creation of differentiated cells for medical uses) does not have to change the way we see the other possibilities, just as the availability of termination of pregnancy does not change the way we see and value each other at present. A child is very easy to distinguish from pancreatic tissue grown in a laboratory, whatever the origins of that tissue. Cregan presents several other arguments against pursuing therapeutic cloning. The technology might not work, or might not be safe. Well, of course this is true, but it is hardly an argument for not trying. If it were, we might as well abandon all medical research. The technology might require the use of thousands of eggs and this could lead to the exploitation of the poor; this is not an argument against developing the technology, but ( if the requirement for many eggs is a reality once the technology is ready for clinical use) it is an argument for regulation of the technology if and when it becomes reality. There is precedent for this in the banning of trade in human organs for transplantation, without which largescale exploitation of the poor by Australians with organ failure might occur. The long waiting lists for transplantation attest to the effectiveness of this regulation, although I would like to think that most people would act ethically, even without legal constraints. In any case, many thousands of eggs are harvested every year in Australia during IVF procedures, mostly not from the very poor. It is not hard to imagine a scenario in which some of these could wind up being used for therapeutic cloning. Moreover, many women may be willing to donate eggs if they could be used to cure people of serious disorders, just as many people already donate bone marrow for the treatment of malignancies. Finally, as a clinician I reject the suggestion that wishing to cure someone of a serious disease or disability implies a belief that their life without a cure is not worth living. Of course one can value a person's life as it is, but still wish to alleviate their suffering: this is the foundation of clinical medicine.


This study aims to describe the level of academic procrastination based on the intensity of the use of social media in Palembang State Middle School 18. The population consisted of 120 students from class VIII with sample selection using a purposive sampling technique so that getting samples for each category in the form of: Light Users (numbered users) totaling 41 students, Medium Users (medium users) totaling 37 students, and Heavy Users 42 students. Research uses a quantitative approach with survey methods. The data collection technique used a closed questionnaire to measure the intensity of social media use as well as sample determination and the Likert scale to measure the tendency of academic procrastination. The data analysis technique used is descriptive quantitative. The results showed that the majority of subjects in the Light Users category were low on academic procrastination with a percentage of 53.7%, the Medium Users category including being on academic procrastination with a percentage of 43.2% and the Heavy Users category including academic procrastination with 45.3% . The results showed that the more often students used social media, the higher the tendency to do academic procrastination.


We present recent results on the critical and pseudo-critical temperatures in (2+1)-flavor QCD with a physical strange quark mass and two degenerate light quark masses extrapolated to the chiral limit and tuned to the physical value, respectively. We furthermore discuss implication of the observed low chiral phase transition temperature, Tc0=132_{-6}^{+3} MeV, for the structure of cumulants of conserved charge fluctuations at vanishing baryon chemical potential and consequences for the possible location of the QCD critical endpoint in the QCD phase diagram at non-zero baryon chemical potential.


Plasma membrane integrity maintenance is crucial for cell survival. Plasma membrane proteins are under tight regulation and under certain conditions are actively removed from the membrane allowing cells to adapt to changing environment. Proteins blocked in the cell membrane may interact with other molecules and form toxic aggregates. Ubiquitin is one of the most important modifiers targeting proteins for degradation and/or regulating protein
functions. Several quality control mechanisms have been identified in eukaryotic cells: chaperone-
dependent system that recognizes and ubiquitinates misfolded or redundant membrane
proteins; protein-intrinsic LID-degron system, based on recognition of degron and ARTs-Rsp5
network that controls quality of membrane transporters. Rsp5, a Nedd4-family E3 ubiquitin
ligase, is crucial for plasma membrane proteins ubiquitination. Rsp5-dependent ubiquitin
action acts as a sorting signal for internalization of a membrane protein via endocytosis, recognition
by the ESCRT system and vacuolar degradation. Rsp5 builds poliUb-chains on K63 and
recognizes substrates through various adaptor proteins. Most of the identified Rsp5 adaptors
belongs to the α-arrestin family. Plasma membrane protein ubiquitination and degradation
disorders may cause neurodegenerative and cardiovascular diseases. The yeast Saccharomyces
cerevisiae is one of the best models for studying trafficking pathways of membrane proteins
and ubiquitination systems.


This invention relates to a medicament comprising a peptide extract of avocado, and can further comprise a composition comprising D-mannoheptulose and / or perseitol, in particular a water-soluble extract of avocado sugars, and / or peptide extract of lupin.Le medicament is for the treatment and / or prevention of diseases related to a modification of innate immunity via increasing production of antimicrobial peptides, preferably the hBD-2, without inducing inflammatory reactions, irritation or intolerances.


Pioneering studies of animal personality appeared in the 1970s (e.g., Adamec, 1975; Buirski, Plutchik, & Kellerman, 1978; Stevenson-Hinde & Zunz, 1978). These studies proposed personality differences and examined behavioral tendencies that would be predicative of those personality traits. These studies began a surge of interest in consistent individual characteristics among individuals of various species, and during the past few years, research has begun to focus on animal personality more seriously. This line of research has resulted in a number of studies revealing individual differences in personality traits in such diverse species as primates, marine mammals, insects, fish, invertebrates, and birds (Gosling, 2001). Animal personality is defined as an individual animal's unique and stable patterns of behavior (Gosling, 2001). Based on this definition, there are often two main goals of animal personality research: 1) determine if individuals within a species exhibit distinctive patterns of behavior and 2) determine if these patterns are consistent and stable over time and in a variety of contexts.


The invention relates to a refrigeration appliance, in particular domestic refrigerator, with at least one cooling chamber (102) which (I) is used for cooling of the cooling air through an outdoor air circuit thermally coupled to cool outside air, which outside air circuit (I) with the interposition of a heat exchanger (210) having a cooling room air circuit (II) is in communication, by means of which the cold outside air is transferred to the cooling air. the space in the cooling circuit (II) is guided circulating cooling air through the heat exchanger (210) according to the invention.


Infrared spectra of methyl, [2H3]methyl, ethyl, and [2H5]ethyl acrylates and trans-crotonates in solution in carbon disulphide are reported. Band intensity measurements at temperatures between –110 and 35 °C together with changes in the appearance of these bands on solidification of the solution are interpreted in terms of conformational equilibria between high- and low-energy forms. The additional enthalpies (ΔH°) of the high-energy forms are remeasured for methyl acrylate as 326 ± 18 cal mol–1 and for methyl trans-crotonate as 306 ± 30 cal mol–1. The additional entropy (ΔS°) of the high-energy form of methyl trans-crotonate is estimated as 1·5 ± 1·0 cal mol–1 K–1.


As one of the basic assumptions of regional economics, the difference of resource endowment plays an important role in the formation of regional competition ability. This paper introduces the economics concept of resource endowment to the research of regional logistics. Based on the regional economic theory and regional logistic theory, this paper studies the objective factors behind the development of regional logistics and the effect of different resource endowment on regional logistics. The research result indicates: Through the identification of strategic resources element affecting the development of regional logistics, it is advantageous to make the strategy of improving regional logistics and to establish the core advantages of regional logistics competition.


It seems an unaccountable pleasure, which the spectators of a well-written tragedy receive from sorrow, terror, anxiety, and other passions, that are in themselves disagreeable and uneasy. The more they are touched and affected, the more are they delighted with the spectacle ... The whole art of the poet is employed, in rouzing and supporting the compassion and indignation, the anxiety and resentment ofhis audience. They are pleased in proportion as they are afflicted, and never are so happy as when they employ tears, sobs, and cries, to give vent to their sorrow, and relieve their heart, swoln with the tenderest sympathy and compassion.1


Tooth pulp contains steroid receptors and therefore is likely to respond to steroids. Steroids and cytokines together can alter steroid receptor content in many tissues; thus, similar mechanisms may exist in tooth pulp. In this study, reverse-transcription/polymerase chain-reaction was used to screen human pulp for the mRNAs encoding receptors for androgen (AR), estrogens (ERβ), and hepatocyte growh factor (HGF: c-Met). AR mRNA content was greater in male pulp vs. female pulp in all age groups. In both genders, AR mRNA content diminished with age. In pulp cell cultures, androstenedione, estradiol-17β, and HGF each stimulated AR mRNA accumulation. Testosterone inhibited, whereas 5α-dihydrotestosterone did not affect, AR mRNA content. ERβ was not hormonally altered in pulp cell cultures. By showing steroid- and cytokine-orchestrated regulation of AR mRNA in vitro, it is possible that age- and/or pathogen-dependent changes in available steroids and cytokines can affect any androgen-responsiveness of pulp.


Based on detailed survey data of land use from 1996 to 2008,this article analysed the dynamic changes of land use from the aspect of both time and spatial.Analysing four factors which have influences on land use structure at the same time to reveal the condition of wuhan land use structure dynamic changes,for the purpose of promoting the development of a harmonious society in this city.The model of land use need further perfection.


DURING the routine postmortem examination of the central nervous system of individuals who had been studied by carotid angiography before death, 5 instances of small emboli containing cotton fibers were recognized. Following this initial observation, the removal of the cervical portions of the carotid arteries in patients who had been subjected to carotid angiography before death was made part of the autopsy routine. This report is concerned with the Fj original and 7 subsequent examples of lesions containing cotton fibers which have Been encountered.


This article examines Rodulfo Brito Foucher's views on autoritharianism and violence. Brito Foucher was an important political opponent under Cardenas' rule. He also was a conservative ideologist who envisioned a "necessary dictature" as an alternative that would put an end to Mexico's decline and corruption. In the essays he published in 1938, Brito Foucher relates specific political events —linked to Tomas Garrido Canabal's regime in Tabasco between 1924 and 1935— to the rejection of the revolution that put in place a dictatorship disguised into a democratic regime. Reviewing Brito Foucher's arguments allows one to reexamine from a new perspective the meaning of two key-concepts within the history of Mexico's social thinking in the 20th century.


A carrier for electrostatographic developers comprising carrier particles comprising metals, metal alloys, metal compounds and mixtures thereof treated with a strongly adhering adsorbable organic dye. This carrier is used with toner particles to develop electrostatic latent images.


This article describes the use of the TOSCA software in the design process of a turbocharger bracket of a medium speed gas or diesel engine. TOSCA is a topology optimization software from Dassault Systemes. This paper shows some intermediate optimized results as wells as the final design.


This paper analyzes the principles of Firewall and N AT , presents the challenges and different solutions for allowing VoIP to traverse the firewalls and NATs. At last, two solutions are recommended to adopt accordin g to present characteristic of VoIP network.


In 1992, the Ontario Geoscience Laboratories (hereafter referred to as the Geoscience Laboratories) moved from Toronto to Sudbury into a new 25 000 ft2 facility. The acquisition of an extensive bank of new equipment and many staffing changes meant all methods were revised and then validated. Thus 7 single element tests, 2 precious metal packages, 2 major element packages by XRF, 7 elements determined by AA, 11 elements by ICP-OES, 8 elements by XRF and 24 elements by ICP-MS were validated. These methods represent the program needs of much of the Ontario Geological Survey. The task had to be completed 'as soon as possible' to minimize the impact on the mapping programs of the Survey which were not interrupted by the move. The tasks of building implementation, method development and validation were undertaken by approximately 12 staff members and were completed in 12 to 18 months. Method validation ensures that a particular analytical methodology using a specific combination of techniques will yield an analytical result that is proven to be correct. It is critical to perform such exercises when procedures are instituted or changed, new equipment procured or staff hired to ensure continuity of data quality. A generic validation program was documented, streamlined and used by all. A detailed outline was drawn up that explained the exercise and listed the steps required. For each method and element, precision, trueness, detection limit, quantification limit, working range, blank level and lack of inherent bias were quantified. These parameters were based on data from a minimum of seven replicates of five to seven SRMs that spanned a wide geological range. SRMs used in calibration or method development could not be included. The data quality objectives were approximately ± 5% precision (2σ) and trueness to meet the stringent data quality objectives of the Geoscience Laboratories. Here, over a 5-year period, precision and trueness are not expected to exceed ± 10%(2σ) when the concentration of an element is more than three times the limit of quantification or 10 times the limit of detection (LOD = 3so). Overall, the exercise was a resounding success. Data from the validation of Ba is used throughout the text to illustrate the principles discussed. The problems that were encountered typically included the availability of certain rock compositions, the level of characterization of some reference materials, the uncertainty on 'known' values and thus method trueness, the definition of detection limit and the difficulty in getting realistic 'blank' determinations for some methods. For the Geoscience Laboratories, the method validation exercise provides a standardized, non-subjective means to ensure the data quality objectives of the facility are met. It also convinces management, staff and clients that an appropriate level of expertise is achieved.


The purpose of study is to investigate the effects of employees" psychological empowerment on job satisfaction, organizational commitment and customer orientation. Moreover we would like to suggest the ideal ways to improve productivity through human resource management and to get competitive advantages for efficient management. In order to achieve the purpose of this, we performed both literature review and empirical research. In total, 301 cases was surveyed and analysed from 13 deluxe hotels which are all located in Seoul and Kyunggido province. The consequences of this research is presented as follows: First, psychological empowerment had an effect on job satisfaction, organizational commitment and customer orientation. Second, job satisfaction had an effect on organizational commitment and customer orientation. Third, organizational commitment had an effect on customer orientation. Fourth, psychological empowerment had an effect on customer orientation through mediating role of job satisfaction, organizational commitment. The implications and the further research directions are discussed.


The importance of space environmental effect on material is addressed. Some examples of the material degradation in a particular space environment are introduced. In order to endorse the material properties requested in a mission, ground-based studies are quite important. However, present deficient ground-based simulation technology cannot perform the accurate assessment of the material degradation in space. On the other hand, infrastructures for the material evaluation using Kibo and International Space Station, is now established after long desire of material scientists and engineers. However, we will face difficulty for retrieve the exposed sample by the retirement of Space Shuttle. Development of new material evaluation methods using small satellite without retrieving the samples and of the accurate ground-based simulation techniques are both highly desired to achieve low-risk missions.


John Lee, San Jose State University JOHN LEE is an Assistant Professor in the Department of Mechanical and Aerospace Engineering at San Jose State University. He teaches in the areas of microelectromechanical systems (MEMS), manufacturing processes, mechanical design, and dynamics. He conducts research in microfluidics and micromechanics applied to MEMS design and fabrication. Contact: firstname.lastname@example.com.


[Objective] The research aimed to detect cattle and sheep-derived components in the feed of ruminants and animalderived feed. [Method]The cattle and sheep-derived components in 131 batches of the feed products(premix, concentrate supplement, complete feed, etc.) of ruminants and animal-derived feed(fish meal,poultry meat powder, pork powder, feather meal, etc.) were detected by real-time fluorescence qualitative PCR. [Result] No cattle and sheep-derived component was detected in all samples. [Conclusion] No cattle and sheep-derived component was found in the detected feed products of ruminants and animal-derived feed. The monitoring of cattle and sheep-derived components should still be strengthened.


Objective: To assess the serum level of Semaphorin 3A in ankylosing spondylitis (AS) patients and to assess its correlation with disease activity. Subjects and Methods: The study was carried on 40 subjects, 20 AS patients (12 males and 8 females) fulfilled the 1984 Modified New York criteria for diagnosis of ankylosing spondylitis, and 20 healthy subjects, taken as control group (12 females and 8 males). A consent was taken from all subjects to share in the study. Disease Activity Score (ASDAS) was calculated for AS patients and functional assessment was done using the Bath Ankylosing Spondylitis Functional Index (BASFI). Results: Serum levels of Semaphorin 3A were significantly higher(P<0.05) in AS patients more than controls as it ranged between 0.22-31.48 years with a median of 2.93 in AS patients and (0.04-3.91) with the median of 1.83in controls. Also, there was a significant difference(P<0.05) of Serum Semaphorin 3A level in ankylosing spondylitis patients regarding ASDAS-CRP score being higher in active AS (ASDAS-CRP ≥1.3) and ranged between (2.17-31.48) vs (0.22- 2.23) in the active vs the inactive AS patients respectively. Serum Semaphorin 3A level (ng/ml) in ankylosing spondylitis patients were significantly correlated with ASDAS- CRP (r=0.82), ASDAS-ESR (r=0.76) as p<0.05. Conclusion: Serum levels of Semaphorin 3A were increased in patients with ankylosing sponndylitis and correlated with disease activity. So, Semaphorin 3A can be used as a biomarker for AS disease activity.


The invention relates to a method for preparing a double-mercerized yarn-dyed jacquard fabric, which comprises: (1) performing mercerization treatment of 100s/2 or 120s/2 high grade all-cotton yarns in solution of NaOH, dyeing, drying and spooling to form tight cones; (2) warping; (3) weaving on a machine; (4) performing mercerization treatment of the fabric; and (5) inspection and packaging. In the invention, the warps and wefts are made of the same material, so the fabric offers the same touchfeel in texture; due to the mercerization of the yarns and the mercerization of the fabric, the finished fabric has the same effect as silk; and the prepared fabric is uniform in fabric cloth width, excellent in color and luster, clear in grain, full in particle and strong in three-dimensional sense and has the characteristics of beautiful appearance, high breathability, touchfeel comfort and the like.


Nitroaromatic compounds (NACs) are commonly found as soil contaminants in military training sites and manufacturing facilities, and may adversely affect human and ecosystem health. Exchangeable cation effects on p-nitrocyanobenzene (p-NCB) and 1,4d-initrobenzene (1,4-DNB) sorption by the Webster (fine loamy, mixed, mesic Typic Haplaquoll) soil series A (WA) and B (WB) horizons were determined from batch sorption experiments. Smectite is the most abundant mineral in the horizons of this soil. Soil organic matter (SOM) removal increased p-NCB sorption to the WA and WB horizons by ∼1.5 times, and increased 1,4-DNB sorption to the A and B horizons by ∼1.2 to 2.2 times, respectively. Greater sorption of NACs by whole soils after SOM removal suggests that SOM suppresses p-NCB and 1,4-DNB sorption by soil mineral components. Clay (<2-μm fraction) removal decreased p-NCB sorption to the WA and WB horizons by ∼8 and 11 times, respectively; clay removal decreased 1,4-DNB sorption to the WA and WB horizons by ∼4.8 and 6.7 times, respectively. Nitroaromatic compound sorption to different soil fractions was measured to identify the independent effects of soil components and exchangeable cations on sorption. For this purpose, 1,2,4-trichlorobenzene (1,2,4-TCB) and 1,4-DNB sorption to two organic soils and a soil devoid of smectites, and p-NCB sorption to whole soil and the soil clay-sized fraction were determined. Exchangeable cation type was found to minimally affect sorption of 1,2,4-TCB, p-NCB, and 1,4-DNB by SOM. Sorption of p-NCB to homoionic soil clay-sized fractions was generally greater for clays saturated with monovalent cations than clays saturated with divalent cations. Greater p-NCB sorption followed decreases in cation hydration energy in the order Na + < Li + < < K + < Cs+ and Ca 2+ < Ba 2+ < Mg 2+ . Similar trends were observed for whole-soil samples exchanged with these cations. This indicates that differences in nitroaromatic sorption are due to exchangeable cation effects on the clay mineral fraction.


With the continuous development of construction machinery technology, great breakthroughs have been made in the application of electronic information technology. The control and operation system of construction machinery vehicles refers to the system that applies and receives certain instructions and makes the construction machinery produce specified actions according to the requirements of operators through its power transmission device. Compared with the previous construction machinery, the developing construction machinery has made good achievements in high efficiency, intensification, cost saving and environmental protection. The traditional speed measuring method can not meet the requirement of measuring accuracy of actual walking speed of construction machinery, and can not accurately reflect the actual walking speed and instantaneous motion state of construction machinery. This paper analyzes a kind of construction machinery vehicle using machine vision. It obtains important information through image processing, adopts intelligent control technology based on machine vision as an important control means of power drive, and can judge and control driving according to road conditions, thus improving the accuracy and stability of industrial autonomous transportation..


During the process of oil field development, in order to accurately detect the position, trend and buried depth of oil, gas, and water pipelines or other buried pipelines and cables in oilfields, the 3D imaging system used in detecting these buried pipelines is proposed based on OpenGL in this paper. Firstly, based on the theory of magnetic anomaly detection, the model of earth's magnetic field is established, and the software and hardware of buried pipeline detection system is described. Secondly, by adjusting the scanning time interval and the detecting directions, the buried pipelines are detected in the fields, and then the results of the detection are analyzed in detail. Finally, by analyzing the 3D imaging results of detecting data, the effectiveness of utilizing magnetic anomaly method to detect buried pipelines in oilfield is verified. The field experiment results show that the detection precision of the pipeline detection system designed based on the above-mentioned method can reach up to 94.5%. Obviously, the pipeline detection system studied in this paper is of high detecting accuracy and the features of visualized detection.


Fiber reinforced polymers (FRP) strengthening has been demonstrated as an effective method to reinforce or repair the structural elements in the application of civil engineering. One issue that affects the effectiveness of FRP bonded system is the interfacial integrity between FRP and bonded substrate. The interfacial defect can cause the deterioration of the performance of strengthened/repaired structures, which should be identified as early as possible. Compared with conventional non-destructive techniques (NDTs), image acquisition method, such as high-speed camera, has received increasing attention due to the advantages of its non-sensor/wiring requirements. Coupled with proper video processing techniques, the high-speed camera has been reported as an effective tool in the interfacial defect detection for FRP bonded system. Moreover, the accuracy of results from high-speed camera is sensitive to the excitation resources applied on the FRP bonded system, since the vibration response of FRP varies under different excitation methods. In this research, three typical excitation methods for FRP bonded system, i.e. mechanical impact excitation, air pressure excitation and acoustic excitation, were tested to evaluate their effects on the detection accuracy using high-speed camera in FRP bonded system. The findings provide practical recommendations on the selection of proper excitation methods for the applications of high-speed cameras in the defect detection of FRP bonded system.


Objective To explore the feasibility and clinical effect of percutaneous vertebroplasty(PVP) via unilateral transpedicular approach guided by preoperative CT parameters.Methods PVP was carried out in 51 patients with a total of 67 diseased vertebral bodies.The puncture angle and skin needle entry point were determined by the related parameters measured on preoperative CT images.PVP procedure was accomplished based on the measurement results.The effect of pain relief was evaluated by the visual analogue score(VAS)and WHO criterion.SPSS 13.0 software was employed for statistical analysis.The estimating data were statistically analyzed with paired t-test and the results were expressed in the form of(x ± s).Results All procedures were successfully accomplished and no serious complications occurred.The technical success rate of unilateral transpedicular approach was 95.5%.The measurements obtained from CT images could not meet the requirements of unilateral puncturing approach in three cases and bilateral puncturing approaches had to be adopted.After the treatment pain relief was obtained in all patients and no serious complications developed during follow-up period.Conclusion When performing PVP,the puncturing angle and needle entry point on the skin are different from patient to patient.The related parameters measured on the preoperative CT scans are very helpful in determining the feasibility of performing PVP procedure by using unilateral transpedicular approach,in this way,the safety and the success rate of the procedure can be effectively improved.


Salmonella enterica are members of a Gram-negative enteropathogenic bacteria family, which are able to infect a great diversity of hosts, including human. According to serotypes and hosts, Salmonella enterica cause a wide range of foodand water-borne diseases ranging from self-limiting gastroenteritis to systemic typhoid fever. Moreover, no other known bacterial pathogens belonging to a single species show such a remarkable variation in their host specificity. Ubiquitous serotypes such as Typhimurium and Enteritidis tend to produce acute but self-limiting enteritis in a wide range of hosts, whereas host-specific serotypes are associated with severe systemic disease in healthy outbred adults of a single species that may not involve diarrhoea (e.g. Gallinarum in poultry). Host-restricted serotypes are primarily associated with systemic disease in one host (e.g. Dublin in cattle, Choleraesuis in pigs), but may cause disease in a limited number of other species (Velge et al., 2005).


In this paper we study the complex representations of arbitrary finite monoids M. Let 9 be an irreducible character of a maximal subgroup (or Schiitzenberger group) of M. Related to the Schiitzenberger representations of M, we construct left and right induced characters 9~ and 9~ of the unit group G of M. We show that the sum of suitable intertwining numbers (0~. 9~) is equal to the number of conjugacy classes of M. The semigroup induced character 6 of G is shown to be a summand of 6T Pi 9~ with equality occurring in many natural examples. We apply our results to the full transformation semigroup, determining explicitly all the irreducible characters. We also study the algebra of invariants of the complex monoid algebra. We use this to show that for the multiplicative monoid of triangular matrices over a finite field, all the irreducible complex representations restrict to irreducible representations of the unit group.


(57) Abstract: The present invention relates to an epitaxial growth method for growing a single crystal aluminum nitride from a mixture of nitrogen and aluminum vapor, the method includes the following steps: the substrate (4) and an aluminum source (5 ) is positioned opposite to each other in the growth chamber; the substrate is heated to a temperature to ensure the growth of aluminum nitride, by this, the temperature at this growth chamber (3) is maintained, pressure of the mixture of nitrogen and aluminum vapors are maintained.


The purpose of this paper is to find educational values of Piil Pesenggiri. Qualitative methods are used to describes and analyze of Piil Pesenggiri by collected the books, articles, journals, etc. The findings show that Piil Pesenggiri consists of four pillars; (1) juluk adok, (2) nemui nyimah, (3) nengah nyappor, and (4) sakai sambayan. The four pillars are framing two dimensions; personal and social. The personal dimension relates to being a good people to constructing the self-student and self-respect. The social dimension relates to the solidarity of individual and each other. Based on the analysis, the findings of educational values of Piil Pesenggiri are morality, religiosity, solidarity, and tolerance. It can be used to prevent social problems in human life.


Introduction Conjuring Cultures: Daoism in Japan Jeffrey L. Richey Part 1: Arrivals 1. Pleiades Retrieved: A Chinese Asterism's Journey to Japan Jonathan Smith 2. Daoist Deities in Ancient Japan: Household Deities, Jade Women and Popular Religious Practice Michael Como 3. Framing Daoist Fragments, 670-750 Herman Ooms 4. Daoist Resonance in a "Perfected Immortal": A Case Study of Awata no Ason Mahito N. Harry Rothschild and Kristen Knapp Part 2: Assimilations 5. Onmyodo Divination Techniques and Daoism Kunio Miura (trans. Stephen Eskildsen) 6. The Laozi and the Emergence of Shinto at Ise Mark Teeuwen 7. Demarcation from Daoism in Shinran's Kyogyoshinsho Michael Conway 8. Koshin: Expelling Daoist Demons with Buddhist Means Livia Kohn Part 3: Apparitions 9. The Zhuangzi, Haikai, and the Poetry of Basho Peipei Qiu 10. The Eight Trigrams and Their Changes: Divination in Early Modern Japan Matthias Hayek 11. Crossing the Borders: The Magical Practices of Izanagi-ryu Carolyn Pang


Because they rely heavily on physical comedy, many Hollywood slapstick films can be understood as comic meditations on the place and nature of the human body. Focusing on the works of Charlie Chaplin, Buster Keaton, Harold Lloyd, and Laurel and Hardy, among others, this book examines ways that the body represents or interacts with the mind, setting, voice and machines in slapstick films. It also covers female performances in slapstick and brutality and suffering in the slapstick tradition.


Interpretation industry in Dalian has run into development bottleneck mainly due to the backward teaching of interpretation practice,ignorance of the problem by society and students,and the lack of qualified teaching staff.Reform on interpretation teaching practice should be implemented in the aspects of curriculum,and teaching means and patterns.Drawing on the globally advanced experiences and the formula KI=KL+EK+S(P+AP),the new framework of curriculum could be established.Guided by the theory of constructivism,multimedia and internet technology should be effectively applied.New teaching patterns,such as "co-teaching",integration with the society,should be adopted.The reform on interpretation teaching practice will meet the increasing need of the Dalian market.


The prefatory picture-cycles in English 12th-century Psalters vary considerably both in the planning of their Old Testament component and in the way that this is grafted on to the New Testament elements. This study first establishes a contemporary context for the experiments which we find in the Winchester Psalter, Cotton MS Nero C. IV, and then looks critically at the premises and the arguments advanced in recently published discussions of the problematic first eight miniatures in the Winchester Psalter. The identification of the scene in the lower register of what is now folio 4 as the Annunciation to Joachim is reaffirmed, and the meaning of the much-disputed middle register is explained as a pictorial bridge between the Exodus scenes in the upper register and Pseudo-Matthew in the lower. Another "traditional" view, namely that the Genesis cycle is incomplete at the beginning, is reasserted both for iconographical and codicological reasons. An alternative reconstruction of the gathering containing the first eight miniatures is proposed, in which the miniatures are arranged in pairs, as openings. The visual advantage of this reconstruction is immediately apparent in the juxtaposition of the two-part miniatures on the present folios 7 and 6. Also accounted for in practical terms is the eventual disarray of the miniatures.


An accurate description of the relative permeability–saturation function is crucial for reliable predictions of multi‐phase flow behavior in subsurface applications. Although extensive efforts have been put forth to investigate the relative permeability behavior in different types of porous media, only few studies have focused on rough‐walled fractures. In this work, we present an entirely new, cost‐effective, heavily‐parallelized, dynamic pore‐network modeling framework that is employed to conduct a systematic study of relative permeability curves under two‐phase flow conditions in rough‐walled fractures. We first build a two‐dimensional (101.42 × 24.86 mm2) equivalent pore network of a Berea sandstone fracture from its x‐ray images. Subsequently, dynamic primary drainage and imbibition simulations are conducted in the fracture. We show that the two‐phase fluid occupancy maps predicted from the simulations agree well with the fracture fluid configurations obtained via X‐ray computed tomography. Afterward, the validated model is used to probe two‐phase flow properties in a series of synthetic aperture fields generated with a broad range of geometric characteristics including aperture spatial correlation length (normalized correlation length varying from 0.05 to 0.95), anisotropy factor (0.25–4), surface roughness (normalized fracture roughness varying from 0.05 to 0.4), and mean aperture size (50–800 μm). The generated results provide novel insights into the effects of these features on two‐phase flow properties such as fluid–fluid interfacial area, phase interference, and relative permeability. Moreover, based on the simulation results we propose two new correlations to describe the relative permeability curves for primary drainage and imbibition processes in rough‐walled fractures.