Acne or acne vulgaris is a chronic inflammatory skin disease in which there is involvement of the pilosebaceous unit. It is evidenced by the presence of open/closed comedones, inflammatory lesions, and papules, pustules, or nodules. Acne results from the interaction of several factors such as: increased sebum production by sebaceous glands, sebaceous gland hyperplasia, and hyperkeratinization of the follicle that impedes normal desquamation of follicular keratinocytes and obstructs the follicle.
Lipids and debris accumulate in the plugged follicle, creating an appropriate environment for Propionibacterium acnes to proliferate. This anaerobic bacterium causes a local immune reaction in which inflammatory cells play a role by producing chemical mediators. Such process extends to the dermis.
El acné común o acné vulgar es una dermatosis inflamatoria crónica en la cual existe un trastorno en la unidad pilosebácea. Se evidencia por la presencia de comedones (abiertos o cerrados), lesiones inflamatorias y pápulas, pústulas o nódulos.