The first total-body positron emission tomography (TB-PET) scanner represents a radical change for experimental medicine and diagnostic health care.
Identification of maturation stages of V3-glycan neutralizing antibodies explains the long duration required for their development.
Anti-CD47 antibody is effective for treating malignant pediatric brain tumors without detectable toxicity in patient-derived xenograft models.
A report of a patient treated with ex vivo lentiviral gene transfer to hematopoietic stem cells shows the promise of gene therapy for sickle cell anemia.
Personalized genome-scale metabolic models augment clinical hepatic steatosis data and motivate treatment based on glutathione repletion.
Enveloped virus infection may be linked to the origin of sexual reproduction.
Human neurons transplanted into a mouse model for Alzheimer’s disease show human-specific vulnerability to β-amyloid plaques and may help to identify new therapeutic targets.