A Miami-Dade County mosquito control worker sprays around a home in the Wynwood area of Miami on Monday, Aug. 1, 2016.
Health officials have identified at least 14 apparently mosquito-borne Zika infections, 12 of which are in a small area in and near Wynwood.
"The bottom line of this announcement is that we advise pregnant women to avoid travel to this area and pregnant women who live or work in this area and their partners to make every effort to avoid mosquito bites and to prevent sexual transmission of Zika," said Dr. Tom Frieden, head of the CDC, in a press call on Monday afternoon.
Frieden also said any pregnant women who live in or have traveled to the area since June 15th should talk to their doctors about getting screened for the disease.
Exposure to Zika virus during pregnancy has been linked to microcephaly, a condition in which babies are born with abnormally small heads and incomplete brain development. Florida has already reported one baby born with the condition after the mother contracted the virus during a trip abroad.
According to the Florida Department of Health (DOH), there are currently 55 cases in the state involving pregnant women and 333 cases in total.
News of four recent cases of Zika acquired by mosquito bites in neighborhoods north of downtown Miami was not received with concern by owners and patrons of restaurants and bars in the popular area of Wynwood.
The streets in and around the Wynwood area were busy and crowded this Friday with people too shy to talk about the virus.
Four people in Florida who have Zika may have contracted the virus in the United States, according to the Florida Department of Health.
In a press release Wednesday, the department said it's investigating two more non-travel-related cases. That brings the total of potentially non-travel-related cases to four: two in Broward County and two in Miami-Dade County.
Wednesday's news raises concerns that mosquitoes in Florida may be spreading the virus.
The Food and Drug Administration (FDA) has issued a temporary ban on all blood collections in Broward and Miami Dade Counties that are not screened for the Zika Virus.
The announcement comes a week after the Florida Health Department and the Center for Disease Control (CDC) launched investigations of four cases in Broward and Miami-Dade counties that could have been acquired by local mosquitoes.
The Florida Department of Health (FDH) confirmed the first case of a baby born with microcephaly in the state after the mother contracted the Zika virus.