For Atrial Fibrillation: This drug has caused edema in the lower legs since I have been using it, very painful when I put a finger for pressure on my skin from the knees down to the feet. I am considering going off this medication.
For Atrial Fibrillation: My 83 y.o. father was started on digoxin for atrial fibrillation. While it did great with controlling his heart rate it also caused him to have marked depression, anorexia and confusion. Thank heavens we went back to his PCP and they stopped it.
See the full digoxin side effects document.