Supervior: Professor Jiasheng Tu-leading researcher in pharmaceutics and functional excipients, who is the committee of USP and ChP.
Lecturer, Department of Pharmaceutics, China Pharmaceutical University, Nanjing, China, Jul.
Application of the micro environment sensitive cell penetrating peptide based on the reversible regulation of static charge in the functional design of the two affinity carrier material, the National Natural Science Funds for Young Scholar(81501579), 2016.
Design and evaluation of polymeric micelles modified by acid sensitive cells, Natural Science Foundation of Jiangsu Province (BK20150702), 2015.
Study on the improvement of the subject of Pharmacopoeia standards, National Pharmacopoeia Commission, 2013.
Establishment of quality standard for injection accessories and functional inspection method, National Pharmacopoeia Commission, 2011.
Design and evaluations on CD44-targeted hyaluronate self-assembly micellar nanocarriers for antitumor siRNA delivery, National Natural Foundation Project (81072588), 2011.
Study on multivesicular liposome formulations for the sustained delivery of ropivacaine hydrochloride.
Targeted Delivery of Small and Macromolecular Drugs (ISBN：142008772X), Editorial Board Member, CRC Press. Taylor & Francis Group press, 2010.
Shen Y, Wang J, Li Y, Tian Y, Sun H, Ouahab A, Tu J, Wang B, Sun C, Co-delivery of siRNA and paclitaxel into cancer cells by hyaluronic acid modified redox-sensitive disulfide-crosslinked PLGA–PEI nanoparticles .RSC Advances, 2015, 5(58): 46464-46479.
Tian Y, Shen Y, Jv M, Synthesis, characterization and evaluation of tinidazole-loaded mPEG–PDLLA (10/90) in situ gel forming system for periodontitis treatment, Drug delivery, 2015: 1-10.
Li Y, Zhang J, Wang B, Tu J, Shen Y, Ouahab A, Co-delivery of siRNA and hypericin into cancer cells by hyaluronic acid modified PLGA-PEI nanoparticles, Drug development and industrial pharmacy, 2015: 1-10.
Li C, Li S, Tu T, Qi X, Xiong Y, Du S, Shen Y, Tu J,Sun C, Paclitaxel-loaded cholesterol-conjugated polyoxyethylene sorbitol oleate polymeric micelles for glioblastoma therapy across the blood-brain barrier, Polymer Chemistry, 2015, 6, (14): 2740-2751.
Yang C, Shen Y, Wang J, Ouahab A, Zhang T, Tu J. Cationic polymer-based micro-emulgel with self-preserving ability for transdermal delivery of diclofenac sodium.Drug Deliv.2015, 22(6): 814-822.
Shen Y, Ling X, Jiang W, Du S, Lu Y, Tu J. Formulation and evaluation of Cyclosporin A emulgel for ocular delivery. Drug Deliv. 2015, 22(7):911-917.
Xu Y, Shen Y, Ouahab A, Li C, Xiong Y, Tu J. Antitumor activity of TNF-α after intratumoral injection using an in situ thermosensitive hydrogel. Drug Dev Ind Pharm. 2015, 41(3): 369-374.
Shi J, Zhang J, Shen Y, Tang L, Zhao J, Tu J, Tian Y, Feng Y.Arginine-stabilized mPEG-PDLLA (50/50) polymeric micelles of docetaxel by electrostatic mechanism for tumor-targeted delivery. Drug Deliv. 2015, 22(2): 168-181.
Xu Y, Shen Y, Jin X, Tu J, Optimization of Ophthalmic Liposome of Ganciclovir by Box-Behnken Design, Lat. Am. J. Pharm, 2014, 33(2): 251-7.
Ouahab A, Shao C, Shen Y, Tu J, Development and characterization of stabilized double loaded mPEG-PDLLA micelles for simultaneous delivery of paclitaxel and docetaxel, Drug Development and Industrial Pharmacy, 2014, 40(7): 860-868.
Li C, Shen Y, Sun C, Nihad C, Tu J.Immunosafety and chronic toxicity evaluation of monomethoxypoly(ethylene glycol)-b-poly(lactic acid) polymer micelles for paclitaxel delivery.Drug Deliv. 2014, 5:1-8.
Li C, Sun C, Li S, Han P, Sun H, Ouahab A, Shen Y, Xu Y, Xiong Y, Tu J.Novel designed polyoxyethylene nonionic surfactant with improved safety and efficiency for anticancer drug delivery.Int J Nanomedicine. 2014 ,9:2089-100.
Ouahab A, Cheraga N, Onoja V, Shen Y, Tu J.Novel pH-sensitive charge-reversal cell penetrating peptide conjugated PEG-PLA micelles for docetaxel delivery: in vitro study.Int J Pharm. 2014 , 466(1-2):233-45.
Shen Y, Minli Jv, Chunmeng Sun, Daquan Chen, and Jiasheng Tu. Ocular pharmacokinetics and bioequivalence study of azithromycin in rabbits by liquid chromatography–tandem mass spectrometry (LC–MS/MS) , Journal of Liquid Chromatography & Related Technologies, 2013, 36:1–16.
Xiong Y, Jiang W, Shen Y, Li H, Sun C, Ouahab A, Tu J. A poly(γ, L-glutamic acid)-citric acid based nanoconjugate for cisplatin delivery. Biomaterials. 2012, 33(29): 7182-7193.
Sun C, Shen Y, Sun D, Hang T, Tu J. Method development and validation for the determination of indiquinoline tartrate, a novel kappa opioid agonist, and its related substances by high-performance liquid chromatography. J Chromatogr Sci. 2012, 50(4):343-8.
Shen Yan, Lu Yang, Jv Minli, Hu Jinshan, Li Qian, Tu Jiasheng. Enhancing effect of Labrasol on the intestinal absorption of ganciclovir in rats. Drug Dev Ind Pharm. 2011, 37(12): 1415-1421.
Shen Yan, Wang Buhai, Lu Yang, Ouahab A, Li Qian, Tu Jiasheng. A novel tumor-targeted delivery system with hydrophobized hyaluronic acid-spermine conjugates (HHSCs) for efficient receptor-mediated siRNA delivery. Int J Pharm. 2011, 414(1-2): 233-243.
Shen Yan, Ji Yuanxin, Xu Shengjie, Chen Daquan, Tu Jiasheng. Multivesicular liposome formulations for the sustained delivery of ropivacaine hydrochloride: preparation, characterization, and pharmacokinetics. Drug Deliv. 2011, 18(5): 361-366.
Shen Yan, Tu Jia-sheng. Rapid, sensitive and selective liquid chromatography- tandem mass spectrometry (LC-MS/MS) method for the quantification of topically applied Azithromycin in rabbit conjunctiva tissues. Journal of Pharmaceutical and Biomedical Analysis.2010,52(1):99-104.
Shen Yan, Tu Jia-sheng. Determination of Preservatives—Benzalkonium Chloride in Clinical Ophthalmic Drops of Azithromycin by High-performance Liquid Chromatography Method. Journal of Zhejiang University SCIENCE B: Biomedicine & Biotechnology, 2009, 10(12):877-882.
Shen Yan, Tu Jia-sheng. Synthesis and Characterization of Low Molecular Weight Hyaluronic acid-based cationic Micelles for efficient siRNA delivery. Carbohydrate Polymers, 20097,7(1): 95-104.
Shen Yan, Tu Jia-sheng, Preparation and ocular pharmacokinetics of ganciclovir liposomes. AAPS Journal, 2007,9(3):E371-7.
2. 2013, Second Prize of Teaching Competition for Young Teachers of China Pharmaceutical University.