Early breast cancer: . Adjuvant treatment of early breast cancer in postmenopausal women with oestrogen/progesterone-receptor-positive disease. . Advanced breast cancer :. First line treatment of advanced breast cancer in postmenopausal women with oestrogen/progesterone-receptor-positive disease. . Treatment of advanced breast cancer in postmenopausal women with disease progression following tamoxifen therapy. Patients with oestrogen-receptor-negative disease and patients who have not responded to previous tamoxifen therapy rarely respond to anastrozole.