Exploits the advances in high performance computing technology in order to distribute particle picking calculations over multiple nodes of a computer cluster. gEMpicker is a highly parallel correlation-based particle picking tool which uses multiple graphics processor units (GPUs) to accelerate the calculation. The user may define a template particle in one of several ways, and this is then used to pick other similar particles from the micrographs by using a fast Fourier transform (FFT) to calculate the correlation score at each pixel between the template and the micrograph. Multiple micrographs may be processed in parallel.
GEMpicker: a highly parallel GPU-accelerated particle picking tool for cryo-electron microscopy.
This work was funded in part by CNRS and by Agence Nationale de la Recherche, grant reference ANR-MNU-006-02.