Immunofluorescent analysis of HepG2 cells, using KNG1 antibody 11926-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 11926-1-AP( Kininogen 1 antibody at dilution of 1:200 (under 10x lens).
Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 11926-1-AP( Kininogen 1 antibody at dilution of 1:200 (under 40x lens).
Kininogens are inhibitors of thiol proteases. Kininogen 1 plays important role in Kinin-kallikrein system. This gene is translated into High-molecular weight kininogen (HMWK) and low-molecular weight kininogen (LMWK) after alternative splicing. HMWK is produced by the liver together with prekallikrein. It acts mainly as a cofactor on coagulation and inflammation, and has no intrinsic catalytic activity. LMWK is produced locally by numerous tissues, and secreted together with tissue kallikrein. 11926-1-AP was generated against N-terminal 300 aa of HMW kininogen. It can bind both HMW and LMW kiniogen.
Novel Serum Biomarkers Detected by Protein Array in Polycystic Ovary Syndrome with Low Progesterone Level.
Proteomic analysis reveals the renoprotective effect of Tribulus terrestris against obesity-related glomerulopathy in rats.