The first book I read by Anne Lamott was Traveling Mercies, which I wrote about in a post back in 2004. While it was dead serious, it was also hysterical. I was reading it as the same time as a friend of mine, and we would call each other and read excerpts over the phone, not being able to finish our sentences for laughing so hard.
I just finished her book, Stitches: A Handbook of Meaning, Hope, and Repair, which came out in 2013. I started it about a year ago but for some reason was interrupted and didn't finish. When I picked it up again a couple weeks ago, I started again from the beginning and was glad for the double dose of her thoughts.
Stitches has Lamott's humorous garnishes, but the tone is more serious than Traveling Mercies. The book is a gathering of "the observations that in troubled times help me find my way once again to what T. S. Eliot called 'the still point of the turning world.'" Her key metaphor is that of stitching together scraps, such as you do when making a quilt, to make something new, whole, and strong.
Any one of those excerpts, as well as any of several hundred other stand-alone great lines or paragraphs in the book are worthy of writing on an index card or printing out and cutting to the size of your back pocket to carry around for quick and frequent referral.