We have recently published an analysis of deficiencies affecting recombination of LGV Left using array Comparative Genomic Hybridization (Jones et al., 2007). A beneficial outcome of this research is the creation of a deficiency map anchored precisely to the physical genome. With breakpoints positioned to within 4kb in most cases the deleted gene complement within each deficiency is known. Such a map can be used to reassess old mapping data and compile current mapping with the confidence that gene candidate lists are definitive. We have included a table of the regions containing the physical breakpoints in the in the deficiencies shown below.
Breakpoint regions for deficiencies on LGV Left.
Jones MR, Chua SY, O’Neil NJ, Johnsen RC, Rose AM, and Baillie DL. (2007). High-resolution array comparative genomic hybridization analysis reveals unanticipated complexity of genetic deficiencies on chromosome V in Caenorhabditis elegans. Mol. Genet. Genomics 282, 37-46.