(mir is' til al' ka hol).
Myristyl Alcohol contains NLT 90.0% of myristyl alcohol (C14H30O), the remainder consisting chiefly of related alcohols.
• A. The retention time of the major peak of the Sample solution corresponds to that of the System suitability solution, as obtained in the Assay.
Sample: Place 2 g in a dry, glass-stoppered, 250-mL flask, and add 2 mL of pyridine, followed by 10 mL of toluene. To the mixture add 10.0 mL of a solution of acetyl chloride, prepared by mixing 10 mL of acetyl chloride with 90 mL of toluene. Insert the stopper in the flask, and immerse in a water bath heated at 60 to 65 for 20 min. Add 25 mL of water, again insert the stopper in the flask, and shake vigorously for several minutes to decompose the excess acetyl chloride.
Blank: Proceed as directed for the Sample, omitting Myristyl Alcohol.
Analysis: Add 0.5 mL of phenolphthalein TS to the Sample and Blank. Titrate each to a permanent pink endpoint with 1 N sodium hydroxide VS, shaking the flask vigorously toward the end of the titration to maintain the contents in an emulsified condition.