The reshuffled side performed well initially against Ludlow but despite their best efforts the hosts scored two first half tries to go in at the break 14-0 in front.
An early Ludlow try put Crewe further on the back foot in the second half, trailing 21-0, but they continued to create chances against a well-drilled side with the try line going begging on a few occasions.
The home side’s defence stood firm and ended the game with two further tries for a final score of 35-0 a scoreline.
On a positive note was the half time debut of no.8 Gregg Saignes, another product of Crewe’s youth system.
Saignes enjoyed a series of good drives with the ball in hand and some big hits at the ruck.
Crewe have a free weekend next and entertain Newcastle at the Vagrants on February 16 – a game they will look to avenge their one point loss in the away fixture.
1st team head coach John Farr said: “Sometimes you just get beaten by a better team.
“Yes, we were missing a couple of key players, yes, some of the boys didn’t work hard enough, but all credit to Ludlow.
“They’re a strong outfit all round and deserve to win this league.