Aciphex is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. It is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).
Aciphex may also be given with an antibiotic to prevent gastric ulcer caused by infection with helicobacter pylori (H. pylori).
Aciphex may also be used for other purposes not listed in this medication guide.