250BC The provinces of Parthia and Greco-Bactria split from the Seleucid Empire.
209BC The King of Selucia, Antiochus III, defeats the Parthians and ends the Greco-Bactrian expansion.
141BC The provinces of Parthia and Greco-Bactria rebel against the Seleucid Persian Empire.
135BC Parthina lose conrtol of eastern provinces of Iran due to raids of Iranian Saka nomads.
95BCParthians regain control of Iran and retain some of the nomads as subjects.
64BC Rome takes control of western Asian coast. This land grab was from Pontus in the North down to Egypt in the South. The kingdoms with in this area are made vasals. Those in close proximity are made client states.
53BC In a foolish bid for presitge, Marcus Licinius Crassus leads a Roman army to be almost totally destroyed by the Parthians at Carrhae.
53AD Rome and Parthia enter into a 10 year war over control of Armenia.