Coenzyme Q10 is found inside the body’s cells. It is key to the functioning of the mitochondria, the powerhouse inside cells that produces the energy the cell needs. Coenzyme Q10, also called CoQ10, also has antioxidant properties and can reduce damage to cells caused by the environment and other factors.
Two small studies have provided evidence that coenzyme Q10 may help prevent migraine.
Side effects from coenzyme Q10 may be lessened if the dose is split up throughout the day and taken with meals. If you notice any of these side effects continue or get worse, you should contact your doctor immediately.
Coenzyme Q10 may interact with other medications or supplements. You should consult your doctor before taking Coenzyme Q10 if you take any of the following: daunorubicin, doxorubicin, timolol, blood pressure medicines, blood thinners, cholesterol medicines and tricyclic antidepressants. Tell your doctor about all medications, vitamins, and supplements you are taking, as some may interact badly and may cause serious side effects.
Before taking CoQ10, speak to your doctor if you have allergies, heart disease, hypoglycemia, diabetes, bleeding disorders, low blood pressure, liver disease or if you take any drugs or supplements that impact blood sugar. Blood sugar levels may need to be monitored because CoQ10 may lower blood sugar.
Women who are pregnant, may become pregnant or who are breastfeeding should not take coenzyme Q10.
People taking CoQ10 supplements are advised not to engage in vigorous exercise.
As always, the best source for advice on treating your migraines is your own migraine specialist. These descriptions of natural remedies are provided only for informational purposes. You should begin no medication or supplement without first checking with your physician.
Silberstein SD. Preventive Migraine Treatment. Continuum: Lifelong Learning in Neurology. 2015;21(4 Headache):973-989. doi:10.1212/CON.0000000000000199.
Coenzyme Q10. Oregon State University. http://lpi.oregonstate.edu/mic/dietary-factors/coenzyme-Q10. Accessed 5/3/18.
Sun-Edelstein C, Mauskop A. Alternative headache treatments: nutraceuticals, behavioral and physical treatments. Headache. 2011 Feb;51(3):469-483. https://doi.org/10.1111/j.1526-4610.2011.01846.x.