ChemIDplus - 1972-08-3 - CYQFCXCEBYINGO-IAGOWNOFSA-N - Dronabinol [USAN:USP:INN] - Similar structures search, synonyms, formulas, resource links, and other chemical information.
A psychoactive compound extracted from the resin of Cannabis sativa (marihuana, hashish). The isomer delta-9-tetrahydrocannabinol (THC) is considered the most active form, producing characteristic mood and perceptual changes associated with this compound.
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Toxicology and Applied Pharmacology. Vol. 25, Pg. 363, 1973.
monkey LD oral > 3150mg/kg (3150mg/kg) Toxicology and Applied Pharmacology. Vol. 25, Pg. 363, 1973.
monkey LD50 intravenous 125mg/kg (125mg/kg) Medical Journal of Australia. Vol. 145, Pg. 82, 1986.
mouse LD50 intracrebral > 12580ug/kg (12.58mg/kg) Research Communiations in Alcohol and Substances of Abuse. Vol. 17, Pg. 151, 1996.
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Archives Internationales de Pharmacodynamie et de Therapie. Vol. 196, Pg. 133, 1972.
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION Annals of the New York Academy of Sciences. Vol. 191, Pg. 74, 1971.
mouse LD50 oral 482mg/kg (482mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
BEHAVIORAL: EXCITEMENT Proceedings of the Society for Experimental Biology and Medicine. Vol. 136, Pg. 260, 1971.
mouse LD50 subcutaneous > 11gm/kg (11000mg/kg) Journal of Pharmacology and Experimental Therapeutics. Vol. 88, Pg. 154, 1946.
BEHAVIORAL: ATAXIA Annals of the New York Academy of Sciences. Vol. 191, Pg. 74, 1971.
BEHAVIORAL: TREMOR Proceedings of the Society for Experimental Biology and Medicine. Vol. 136, Pg. 260, 1971.