Abstract Ethics, Science, Technology, and Engineering: A Global Resource (ESTE-2) is a revised and expanded second edition of the landmark Encyclopedia of Science, Technology, and Ethics, also published by Macmillan Reference USA. This new edition considers both the professional ethics of science and technology—with entirely new coverage of engineering—and the economic, ethical, political, and cultural issues raised by innovations in an increasingly complex and global society. The broad coverage in this new edition supports an interdisciplinary range of courses in applied and professional ethics in all the disciplines that make up the social and quantitative sciences, and also provides a window on African, Asian (Australian, Chinese, Indian, Japanese, and Southeast Asian), European, and American (Northern and Southern) perspectives on policies and ethics practices in the fields of science, technology, and engineering. Aimed at students and researchers, ESTE-2 also embodies a historically and culturally inclusive approach, with articles on specific religions, linguistic and cultural perspectives, as well as philosophical positions. Among the new topics considered in this edition are entries on Article 15 of the International Covenant on Economic, Social and Cultural Rights; Biometrics; Cybersecurity; Drones; Fracking; Global Research Council; Green Chemistry; Healthcare Ethics; Open Access; Philanthropy; Social Media; and Virtual Environments.