Abstract: Objective To compare the efficacy of single-port and three-port thoracoscopic lobectomy in patients with peripheral lung cancer. Methods A total of 176 patients with peripheral lung cancer were divided into single-port(n=80) and three-port groups(n=96). Clinical data, including operative time, intraoperative blood loss, number of lymph nodes dissected, postoperative extubation time, postoperative hospitalization, length of incision, postoperative pain score, and incidence of postoperative complications were compared between the two groups. Results In the single-port group, operative time, postoperative extubation time, and postoperative hospitalization were significantly longer than in the three-port group;however, the incision was shorter and the postoperative pain score was significantly lower than in the three-port group (P < 0.05). There were no significant differences in intraoperative blood loss, number of lymph nodes dissected, and incidence of postoperative complications between the two groups(P > 0.05). However, the incidence of postoperative pleural effusion was higher in the single-port group than in the three-port group(P < 0.05). Conclusion The clinical efficacy of single-port and three-port thoracoscopic lobectomy for peripheral lung cancer is basically the same, and both were safe and effective. Single-port thoracoscopic lobectomy can shorten the incision length, improve scar appearance, and reduce postoperative pain, and is beneficial for postoperative recovery. This technique should be promoted.
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