Tromso-Bergen, NO. 2018 Oct 20-24, 11th MitoEAGLE Training School - MiPschool 2018. From basics of mitochondrial physiology to cardiovascular health and disease.
Abstracts selected for oral presentations (10+5 min) are retained - training for conference presentations with critical discussions.
Meet the expert sessions are emphasized - training in small groups, discussions on a large variety of topics.
An entrance test will be the basis for providing grants to students.
One of the questions raised during the round table was about the physiological consequences of mitochondrial dysfunction at the level of tissues and organisms. I think that this question is very important and that there should be a session aimed at summarizing the current knowledge about it and to develop common and standardized strategies to improve it.
I would definitely like to have disruptive works in different organs/systems. Mitochondria is such a complex subject that can go beyond the molecular part. Translational discussion should be more encouraged towards future applications. Finally, writing/grants/career paths could be added.
Check-in will take place on Saturday, October 20 from 21:00-23:30 pm at Skarven Bar downtown Tromsø, and on the Coastal Express on Sunday from 00:15-01:30 am.
We will disembark on Wednesday, October 24 at 14:30 in Bergen.
The scientific sessions consist of introductory lectures, selected abstract presentations, and discussions in small groups in an open “meet the expert” format.
11 senior scientists will be available for discussions in small groups of about 6, dispersed on separate tables, without slide projection (but with paper and pencil). All participants can 'book' mentors in advance, and rotate after 20-30 min to another booked table. The topics are open, with some 'titles' mentioned in the programme. Students may raise the topic of their abstract for discussion, without formal presentation (you may bring along some printed material or A4-size copy of a poster). Mentors may join to form slightly enlarged groups as appropriate.
The Early Career Investigators (ECIs) will shape the programme for Session E4. The options range from topics selected for a round-table discussion, extended elaboration of any topic covered in the programme, selected summaries of Sessions E1 - E3, continuation of 'Meet the expert' sessions, parallel working group meetings on a list of selected topics, or other great ideas on which our ECIs will take a group decision.
A hardcopy of Version 44 (40 pp.) was handed out at registration. Participants were invited to join as a coauthors during the MitoEAGLE/MiPschool.
Role for mitochondria on the response of highly proliferative and invasive bladder cancer cells to the combined inhibition of mTOR and SIRT1.
High fat-load induces cardioprotection in hearts from obese mice.
Mitochondrion at the crosstalk between metabolic disease and dysfunction in male fertility?
AMPK deficiency elicits changes in OXPHOS in heart mitochondria.
Subchronic in vivo study for the evaluation of hepatic mitochondrial toxicity induced by silver nanoparticles.
OXPHOS efficiency in skeletal and cardiac muscles: Proton leaks, ROS and glutathione redox.
Deacetylation acceleration of BAT thermogenesis.
Two populations of muscle mitochondria: heart and skeletal muscle.
Mitochondrial function during ischemia/reperfusion injury.
Oscillations in mitochondrial ROS production during the early cell cycles in Xenopus embryos.
Dietary and pharmacological treatment of diet-induced obese mice – impact on mitochondrial function.
Cardioprotective flavoniods as a natural modulators of mitoBKCa channel.
Cytoplasmic hybrid cells as a model to characterize the OXPHOS system: control sample with glutamate metabolism defect.
Fads2 exacerbates myocardial ischemia-reperfusion injury in mice: role of mitochondria.
Cardiolipin synthesis in brown and beige fat mitochondria is essential for systemic energy homeostasis.
Cardiac fatty acid oxidation: from in vitro to in vivo.
Mitochondrial dynamics of human Sertoli cells under the effect of leptin and ghrelin.
Sweetheart: Cardiac consequences of fetal exposure to maternal gestational diabetes on the offspring mitochondrial function.
OXPHOS protocols: understanding the patterns.
Alpha-tomatine as a novel membrane-permeabilizing agent for mitochondrial respiration measurements.
Obesity-induced mitochondrial hepatic changes during pregnancy.
Mitochondrial kinases: key players in respiratory control and energy transfer.
Effect of metformin treatment on blood platelet bioenergetics and platelet function in STZ-diabetic and non-diabetic rats.
Investigaton on the role of the mitochondiral deacetylase Sirtuin 3 in adipose tissue.
Intracellular complement factor 3 in the heart – a link to metabolism?
MitoTEMPO ameliorates hyperglycemia induced mitochondrial damage in cardiomyocytes.
Exome analysis sheds light on mitochondrial disorders.
Restrictions to intracellular diffusion of ATP and ADP in cardiomyocytes.
Modeling actomyosin contraction in the heart muscle.
Introducing a platform for primary kinetics data analysis.
Development of analytical assays for the detection and quantification of reactive oxygen and nitrogen species in an animal model of type 1 diabetes - ROS formation involving mitochondrial and NADPH oxidase.
Aging-related accumulation of mitochondrial DNA deletions in skeletal muscle occurs preferentially in Type IIb fibers – high mitophagic flux protects Type I fibers.
Metabolic flexibility and mitochondrial function in the diabetic heart.
Bioenergetic characterization of skin fibroblasts from patients with congenital disorders of glycosylation.
Eligibility: Participants from all COST countries can apply - MitoEAGLE network.
Late registration: The COST MitoEAGLE grant is a financial support to cover part of the local costs (accommodation, meals).
» Notification of MitoEAGLE scholarships for late registrations until September 20.
The maximum number of attendees for the MiP/MitoEAGLE Training School 2018 of 65 participants is reached.
The MitoEAGLE network aims to improve our knowledge on mitochondrial function in health and disease related to Evolution, Age, Gender, Lifestyle and Environment. Every study of mitochondrial (mt) function and disease is faced with EAGLE as the essential background conditions characterizing the individual patient, subject, study group, species, tissue or even cell line.
The MiPsociety is an international organization, based in Europe and operating world-wide and has become a legal body in 2011 continuing a tradition of rigorous mitochondrial bioenergetics; integrating molecular, cellular and organismic physiology and pathology.
The same companies also offer some direct flights from Stockholm Arlanda, Copenhagen, and London Gatwick, but these are seasonal (so do check yourselves if these routes are operating and of interest).
Arctic Airlink also offer direct flights to Tromsø from Luleå and Oulu. The nearest train station is Narvik.
It is 3 1/2 hours’ drive from Tromsø, and it is connected to the Swedish, not the Norwegian, rail network (sj.se). There is a bus link from Narvik, but usually, the train does not meet the last bus to Tromsø.
Training school participants arriving in Tromsø before October 20th can find accommodation on the official travel guide to Tromsø (https://www.visittromso.no/en/Troms%C3%B8%20Airport), which gives you an overview of the various hotels in the city, as well as transportation from the airport to the city center, and what to do in Tromsø.
On Saturday morning (from 10:00 h), we will organize a meeting place at the UiT Campus for training school participants arriving throughout the day (information desk and temporary luggage storage).
Here, you will also have access to Internet and, if needed, a quiet spot for work. Take a taxi from the airport to the university and ask the driver to stop at the main (west) entrance of the MH building (link to map). The meeting place will keep open until 21:00 h.
In the city, luggage lockers are available on the 1st floor in the harbour terminal (link to map). These are card-operated lockers, and cost NOK 60 for a 24-hour period. Available during the terminal opening hours: 05.30-02.00 h.
The registration desk opens at 21:00 h at Skarven Bar downtown Tromsø. This will be our assembly point until the Coastal Express arrives around midnight. We will walk from the bar to the harbor terminal, which is just a couple of minutes away (link to map).