This chapter aims to present classification, occurrence, biological activities and functions of 34 secondary metabolites from Pochonia chlamydosporia (= Verticillium chlamydosporium) and 105 secondary metabolites from the other species of Pochonia reported up to the end of 2015. The secondary metabolites from P. chlamydosporia mainly include resorcylic acid lactone, pyranones, alkaloid and phenolics, while those from the other species of Pochonia belong to polycyclic aromatic compounds, nonaromatic polyketides, phenol-terpenoid hybrids, β-carotene-type neurosporaxanthin, pentanorlanostane triterpenoids, dahiane type diterpenoids, cyclodepsipeptides, verticillin-type diketopiperazines, linear lipopeptide and polyhydroxylated pyrrolizidine. Many of these natural products have attracted much attention for their fascinating molecular architectures and attractive biological activities such as antibacterial, antifungal, antioxidative activities, anti-malarial, antinematicidal, antivirus, antitumour, and other activities.
Wu, F. B., Li, T. X., Yang, M. H., et al. (2015). Guanacastane-type diterpenoids from the insect-associated fungus Verticillium dahlia. Journal of Asian Natural Products Research, 18, 117–124. doi: 10.1080/10286020.2015.1061511.