The Box will vape any amount less than a full trench without any problem. You could put 1/100 of a trench in if that is what you wanted -- and you would get at least 3/100ths vapor from it (and probably a lot more, compared to smoking). If you wanted to vaporize only/exactly one tiny speck -- a single grain -- of material, the Box is one of a very few vapes on the market (short of lab gear) that has any hope of doing this. The only disadvantage is that nearly the same amount of battery power is consumed regardless of the load size.