Epigenetics describes heritable changes to chromatin that can influence gene function. As the basic mechanisms of these changes has become better understood, the influence of epigenetic regulation in development and disease has become a focus.
A number of applications used in epigenetic research such as Chromatin Immunoprecipitation (ChIP) and RNA binding Protein Immunoprecipitation (RIP) require the use of specific and well characterized nuclear antibodies. Our expertise in developing kits and assays for these applications has enabled the development of a large collection of nuclear antibodies against histones, transcription factors, as well as chromatin readers, writers and erasers and other chromatin associated proteins.
With a history of quality that incorporates the Upstate® and Chemicon® brands of reagents and antibodies, we know that specificity is important which is why our highly published histone and modified histone nuclear antibodies are specificity screened using approaches such as our AbSurance Histone Antibody Specificity Arrays.
No matter what your epigenetic target, attention to performance is given to all of our epigenetics antibodies. Select the topic of interest to you to see the selection of related antibodies for your Epigenetics and Nuclear Function research needs.