Research using hematopoietic cells and other suspension cells has been limited in part by low efficiency of gene transfer (transduction and transfection) into these cell types. RetroNectin reagent promotes colocalization of lentivirus or retrovirus with target cells to dramatically enhance transduction efficiency. As a consequence, RetroNectin reagent is now the gold standard transduction enhancer for retroviral/lentiviral gene transfer to hematopoietic cells and holds great promise in clinical application, having been used for over 40 clinical trials.
Research-grade RetroNectin (Cat. # T100A/B; T110A): For research use only. Not for use in diagnostic or therapeutic procedures.
GMP-grade RetroNectin (Cat. # T202): Manufactured as a quality-assured product, according to relevant guidelines for Good Manufacturing Practice (GMP). This product can be used for ex vivo clinical applications.
The method of T-cell expansion by RetroNectin stimulation requires a license from Takara Bio Inc. for uses other than research. Contact bio-licensing@takara-bio.co.jp for details.
RetroNectin GMP grade can be used for ex vivo clinical applications (investigational use only): For GMP grade, please complete and return this form prior to purchase.