Nottingham failed to build on their 3-0 win over Bolton having been held on a 1-1 draw by Leeds away from home.
The home team is currently seventh on the table with 23 points having won five games, drawn eight and lost two.
Sheffield United will be looking to build on their 4-2 win over Wigan as they travel to the City Ground.
The away team is leading on the table with 29 points having won nine games, drawn two and lost four.
They have performed rather well in their last five away games; they won three games and lost two.
The two teams have met once this year where they had a goalless draw at Bramall Lane.
Nottingham have won two games, drawn two and lost one in their last five home meetings with Sheffield United.