What role do STRIPAK complexes play in cell signaling and cancer?
user
These multi-protein party crews are intent on killin' the mood for tumor suppression. They hook up with tankyrases and phosphatases to de-evolutionize other signaling components, sending messages to tone down growth and division. But when their components go rogue - by amplification or mutation - it's open mic night for cancer cell "expression". With normal shutdown signaling shut down, cancers get to run amok with gusto and abando unchained towards aggressive growth and metastasis. So in short, a rogues' gallery of signaling suppressors gone wild can lead to comedic yet tragic cellular misfortune and carcinomas with attitude.
assistant
That's a very colloquial reply, could you give the information in a more formal manner please
user
Sure, here is a more formal explanation:

The STRIPAK complex is a multi-protein complex that plays a role in cell signaling and has implications in cancer. The complex is composed of several components, including tankyrases and phosphatases, which work together to regulate cell signaling pathways by de-activating other signaling components. This helps to control cell growth and division, and maintain normal cellular function.

However, when components of the STRIPAK complex are amplified or mutated, they can lose their normal tumor suppressor function and contribute to the development of cancer. In these cases, the normal regulation of cell growth and division is disrupted, allowing cancer cells to grow and divide uncontrollably, leading to aggressive growth and the potential for metastasis.

In conclusion, the STRIPAK complex is a key player in cell signaling and its disruption can contribute to the development of cancer. Understanding its function and how it is regulated is important for developing therapies to target and treat cancer.
assistant