What is The  total  body  radical  burden  can  be  estimated  by which of the following methods? and explain in detail?
The total body radical burden can be estimated by measuring the products of lipid peroxidation:

FOX (Ferrous Oxidation in Xylenol) Assay 
	Lipid peroxides can be measured by the ferrous oxidation in xylenol orange (FOX) assay. Under acidic conditions, they oxidize Fe 2+ to Fe 3+, which forms a chromophore with xylenol orange.
Estimation of Dialdehydes
	‒ The dialdehydes formed from lipid peroxides can be measured by reaction with thiobarbituric acid, when they form a red fluorescent adduct. The results of this assay are generally reported as total thiobarbituric acid reactive substances,TBARS.
Measurement of Pentane and Methane in Exhaled air
	‒ Peroxidation of ω-6 polyunsaturated fatty acids leads to the formation of pentane, and of-ω3 polyunsaturated fatty acids to ethane, both of which can be measured in exhaled air.

Reference- Review of biochemistry by Rebecca James Perumcheril Pg-412