What is Onion peeling of renal vessels is seen in ? and explain in detail?
Ans. is 'b' i.e., Malignant hypeension There is concentric hyperplastic proliferation of the smooth muscles together with fine concentric layering of collagen to form a hyperplastic aeriolitis (Onion skin lesion). Malignant nephrosclerosis is the form of renal disease associated with malignant or accelerated phase of hypeension. Pathology of kidney in Malignant Hypeension On Gross Inspection : The kidneys are normal in size or slightly enlarged. They have a smooth surface with numerous small petechial hemorrhages. These small pinpoint petechial hemorrhages appear on the coical surface from rupture of aerioles or glomerular capillaries. On Histology ? Two distinct vascular lesions are seen Fibrinoid necrosis It affects the aerioles and is characterized by infiltration of aeriolar walls with eosinophilic material including fibrin, thickening of vessel walls and occasionally, an inflammatory infiltrate (necrotizing aeriolitis). Hyperplastic aeriolitis This affects the interlobular aeries and aerioles. There is concentric hyperplastic proliferation of the smooth muscles together with fine concentric layering of collagen to form a hyperplastic aeriolitis (Onion skin lesion).