What is True about klinefelter syndrome is and explain in detail?
Answer- D. Pubey is attained at normal ageKLINEFELTER SYNDROMEKlinefelter syndrome is the most common chromosomal disorder associated with male hypogonadkm anit infeitity.It is defined classically by a 47, XXY karyotype with variants demonstrating additional X and Y chromosomes.Pathophysiology:The addition of more than 1 extra X or Y chromosome to a male karyotypeSexual characteristics-Patients may lack secondary sexual characterstics because of a decrease in androgen production. This results in sparse facial/ body/sexual hair, a high-pitched voice. They have eunuchoid body habitus.Testicular dysgenesis (small firm testis, testis size <10 mL) may be present in postpubeal patients. Infeility/azoospermia may result from atrophy of the seminifercous tubules. Infeility is seen in practically all individuals with a 47 XXY karyotype. Patients with Klinefelter syndrome mosaicism (46,XY/ 47,XXY) can be feile.