What is Tobacco induced squamous cell carcinoma doesn't involve mutation in and explain in detail?
Tobacco carcinogens induced cancers involve a mutation in the P53 pathway as well as proteins responsible for squamous differentiation . Conversely HPV associated squamous cell carcinomas overexpress P16.Reference: Robbins; 9th edition; Volume II; Oropharyngeal squamous cell carcinoma molecular biology; Page no: 733