What is The gestational age at which a primigravida with cholestasis of pregnancy should be delivered safely: and explain in detail?
Once a diagnosis of intrahepatic cholestasis of pregnancy (ICP) is made, fetal surveillance twice per week with nonstress testing and/or biophysical profiles is recommended. The optimal timing of delivery is at 37-38 weeks or delivery at 36 weeks after confirmation of fetal lung maturity with amniocentesis. Ref: Winkel A.F. (2013). Chapter 30. Dermatologic Disorders in Pregnancy. In A.H. DeCherney, L. Nathan, N. Laufer, A.S. Roman (Eds), CURRENT Diagnosis & Treatment: Obstetrics & Gynecology, 11e.