What is Hypogonadotropic hypogonadism with diabetes mellitus is seen in? and explain in detail?
Prader wili occurs due to deletion of paternal copies of imprinted SNRPN gene and NECDIN gene on chromosome 15q. It presents with: Hypogonadotropic hypogonadism Diabetes mellitus(adult onset) Hyperphagia Obesity Muscle hypotonia Mental retardation