What is Xanthurenic acid, accumulation occurs due to pyridoxine deficiency, is a metabolite of which amino acid? and explain in detail?
In the metabolism of Tryptophan, Kynurenine is an intermediate step.T his step is catalyzed by Kynureninase enzyme which is Vitamin B6 dependent. When there is Vitamin B6 deficiency this pathway is blocked. Hence accumulated Kynurenine is shunted to Xanthurenic acid.