What is A 25-years-old sexually active unmarried male presents with urethral discharge after unprotected sex with a sexual worker. Gram stain pic was given; what may be the possible organisms? and explain in detail?
Ans. a. NeisseriaN. gonorrhoeae is Gram [?] diplococci.Metabolize glucose and produce IgA proteases.Contain lipooligosaccharides (LOS) with strong endotoxin activity.N gonorrhoeae is often intracellular (within neutrophils)GONOCOCCINo polysaccharide capsuleNo maltose metabolizedNo vaccine due to antigenic variation of pilus proteinsSexually or perinatally transmittedCauses gonorrhea, septic arthritis, neonatal conjunctivitis (2-5 days after birth), pelvic inflammatory disease (PID), and Fitz-Hugh- Curtis syndromeCondoms decreases sexual transmission, erythromycin eye ointment prevents neonatal blindnessTreatment: Ceftriaxone + (azithromycin or doxycycline) for possible chlamydial coinfection