What is Resolution of inflammation caused by ? and explain in detail?
Ans. is ' c' i.e., TNF Alfa, IL-10 and IL 1 receptor antagonist Actually no option is absolutely correct: IL-10 is an anti-inflammatory cytokine Cause resolution of inflammation IL-1 is a pro-inflammatory cytokine - IL-1 receptor antagonism will cause resolution of inflammation TNF-a is an pro-inflammatory cytokine - causes inflammation So, in option C, two mediators are correct and one is incorrect regarding resolution of inflammation. However, among the given options only option C is the closest one. Proinflammatory cytokines Major :- IL-1, TNF- alpha, IL-6 Other :- IL-2, IL-4, IL-5, IL-6, IL-8, IL-11, IL-12, IL-15, IL-21, IL-23, ITN- gamma, GM-CSF Anti-inflammatory cytokines IL-4, IL-10, IL-13 Here, you can consider IL-4 as pro-inflammatory cytokine ( as more than one options can be correct in PGIchandigarh).