What is Infeility in Kaagener syndrome is due to? and explain in detail?
Asthenospermia or poor sperm motility is due to missing dynein arms, which is the basic defect of Kaagener's syndrome. It is a ciliopathic, autosomal recessive genetic disorder. Around 90% of individuals with kaagener's have ultrastructural defects affecting protein(s) in the outer and/or innerdynein arms. Triad consist of:- - situs inversus - chronic sinusitis - bronchiectasis.