What is Manish, a patient of hypothyroidism was prescribed thyroxine. Which of the following is the most reliable guide for adjustment of thyroxine dose in him? and explain in detail?
* TSH levels are elevated in a hypothyroid patient (because feedback inhibition by thyroid hormones is not present). * Administration of thyroid hormones (T3 and T4) decreases TSH by contributing to feedback inhibition. * If TSH levels are less than normal, it signifies overeatment whereas high TSH level suggests inadequate treatment.