What is Multiple small aneurym is seen on aoography in which condition and explain in detail?
An aneurysm is defined as a pathologic dilation of a segment of a blood vessel Takayasu's aeritis is an inflammatory and stenotic disease of mediumand large-sized aeries characterized by a strong predilection for the aoic arch and its branches. For this reason, it is often referred to as the aoic arch syndrome.  PATHOLOGY AND PATHOGENESIS The disease involves medium- and large-sized aeries, with a strong predilection for the aoic arch and its branches; the pulmonary aery may also be involved The involvement of the major branches of the aoa is much more marked at their origin than distally. The disease is a panaeritis with inflammatory mononuclear cell infiltrates and occasionally giant cells. There are marked intimal proliferation and fibrosis, scarring and vascularization of the media, and disruption and degeneration of the elastic lamina. Narrowing of the lumen occurs with or without thrombosis. The vasa vasorum are frequently involved. Pathologic changes in various organs reflect the compromise of blood flow through the involved vessels. Immunopathogenic mechanisms, the precise nature of which is unceain, are suspected in this disease. As with several of the vasculitis syndromes, circulating immune complexes have been demonstrated, but their pathogenic significance is unclear. The generalized symptoms include malaise, fever, night sweats, ahralgias, anorexia, and weight loss, which may occur months before vessel involvement is apparent. These symptoms may merge into those related to vascular compromise and organ ischemia. Pulses are commonly absent in the involved vessels, paicularly the subclan aery. Characteristic laboratory findings include an elevated ESR, mild anemia, and elevated immunoglobulin levels. REF:HARRISONS PRINCIPLE&;S OF INTERNAL MEDICINE 18TH EDITION