What is Microscopic examination of a specimen shows 'Psammoma bodies'. They are a characteristic feature of: and explain in detail?
Microscopically, papillary carcinoma consists of single layers of thyroid cells arranged in avascular projections or papillae, which manifest as large pale nuclei, intranuclear inclusion bodies, and anaplastic features. "Psammoma bodies" are laminated calcified spheres and are usually diagnostic of papillary carcinoma. Ref: Lee G.A., Masharani U. (2012). Chapter 42. Disorders of the Thyroid Gland. In A.K. Lalwani (Ed), CURRENT Diagnosis & Treatment in Otolaryngology--Head & Neck Surgery, 3e.