What is A patient with AIDS had an acute episodes of diarrhea. The stool examination revealed an oval structure (8 to 9u in diameter) that was acid-fast and fluorescent blue under ultraviolet light. What is the drug of choice in this patient? and explain in detail?
In the given stool examination there is acid fast oocyst of size 8 to 10 microns most probably of Cyclospora which is a coccidian parasites so the drug of choice of Cyclospora is cotrimazole which is combination of trimethoprim and sulfamethoxazole. CRYPTOSPORIDUM PARVUM *Spherical or oval *4-5 micrometer in diameter *4 sporozoites *Acid fast *Infective when passed in feces *Under ultraviolet illumination, unstained oocyst are autoflourescent CYCLOSPORA CYTANENSIS *Spherical or oval *8-10 micrometer *2 sporocysts (4-6micrometer) , each sporocyst has 2 sporozoites *Acid fast *Not infective when passed in feces *Under ultraviolet illumination, unstained oocysts are autoflourescent. ISOSPORA BELLI *Ellipsoid *20-30 x 10-19 micrometer *2 sporocysts ( 9-14 x 7-12 micrometer) , each sporocyst has 4 sporozoites *Acid fast *Not infective when passed in feces *Under ultraviolet illumination, unstained oocyst are autoflourescent.