What is True about non-depolarizing muscle relaxants – a) Competitive inhibitor of acetylcholineb) Metabolised by pseudocholinesterasec) Mg2+ predisposes the blockd) Ca2+ antagonizes the blocke) Hypothermia prolongs the block and explain in detail?
Non-depolarizing blockers act as competitive antagonists of Ach on Nm receptor at myoneural junction.
Magnesium and hypothermia potentiate the block whereas calcium antagonizes the block.