What is A 25 years old female develops serous otitis media of left ear with cough and occasional hemoptysis and . hematuria and epistaxis for one and half months her. Hemoglobin is 7 gm. B.P. > 170/100, ptoreinuria +++, RA positive (+ve) and ANCA positive (+ve), the likely cause is- and explain in detail?
Answer is A (Wegener's granulomatosis): The patient in question is presenting with the charachteristic triad of Wegener's granutomatosis namely, vasculitis of the upper respiratory tract (serious otitis media and epistaxis), vasculitis of the lower respiratory tract (hemoptysis) and vasculitis of the kidney (proteinuria) Presence of ANCA and Rheumatoid factor fuher suppo the diagnosis of Wegener's granulomatosis which is the single best answer of choice.