What is Which of the following hematological condition is depicted below? and explain in detail?
Ref. Robbins Pathology. 9th edition. Page. 620
 
The picture shows many atpical plasma cells – Diagnostic of Myeloma

Malignant proliferation of plasma cells characterised by monoclonal gammaglobulinaemia (paraproteinaemia)
Cell of origin – Post germinal centre B cells
Stages
	
MGUS
Smoldering myeloma
Myeloma


MGUS – most common plasma cell dyscrasia
Myeloma – CRAB Features
	
Hypercalcemia
Renal Insufficiency
Anemia
Bone lytic lesions