What is Which of the following tests is abnormal in patients with ALS (Amyotrophic Lateral Sclerosis)? and explain in detail?
ALS Neurodegenerative disorder characterized by death of anterior horn cells in the spinal cord and their brainstem homologs innervating bulbar muscles. V.E.P is used for evaluation of optic nerve involvement in multiple sclerosis. CT/MRI spine cannot visualize loss of anterior horn cells or pyramidal cells in the coex. In motor neuron disease: Peripheral nerve conduction studies Electromyography Above both is done to get diagnosis of Amyotrophic lateral sclerosis.