What is The commonest histological finding in Hypeensive Nephrosclerosis is and explain in detail?
"Hypeensive Nephrosclerosis"Lesser degrees of hypeension induce less severe, but prevalent changes in kidney vessels and loss of kidney function; a large poion of patients reaching ESRD without a specific etiologic diagnosis are assigned the designation "hypeensive nephrosclerosis".Characterised by afferent aeriolar thickening with deposition of homogeneous eosinophilic material (hyaline aeriolosclerosis) associated with narrowing of vascular lumina.Similar vessel changes are associated with aging, dyslipidemia, and glucose intolerance. Antihypeensive therapy slows the progression of proteinuric kidney diseases and reduces the excessive cardiovascular risks associated with CKD, but it does not alter the course of kidney dysfunction identified specifically as hypeensive nephrosclerosis.Ref: Harrison's 18/e p2047