What is Which organ is NOT affected by Plasmodium falciparum? and explain in detail?
The trophozoites of Plasmodium falciparum disappears from peripheral circulation after about 24 hrs. By then a strain specific high molecular weight antigen appears on the surface of infected red cells, associated with knob like projections on the erythrocyte membrane. Such red cells disappear from peripheral circulation and adhere to the walls of venules and capillaries in the internal organs like brain, hea, kidney, lungs, spleen, intestine, bone marrow and placenta. Ref: Paniker's textbook of parasitology, 6th ed page 80.