What is With increase in age which of the following is true for lungs? and explain in detail?
Anatomical and Physiological changes of respiratory system with ageing: Anatomical Air space size: Increased Compliance Chest wall compliance : Decreased Lung compliance: Increased to unchanged Total respiratory system compliance: Decreased Muscle strength Maximum inspiratory pressure(MIP): Decreased Trans diaphragmatic pressure (Pdi): Decreased Maximum voluntary ventilation (MVV): Decreased Lung Function FEV1: Decreased FVC: Decreased TLC: Unchanged Vital capacity: Decreased Functional residual capacity: Increased Residual volume: Increased DLCO/VA: Decreased Excercise capacity VO2 max: Decreased Dead space ventilation: increased Immunology Bronchial fluid Neutrophils %: Increased Ratio of CD4+/CD8+ cells: Increased Epilthelial lining fluid antioxidants: Decreased Ref: Guyton and Hall Textbook of Medical Physiology 13th edition Pgno: 499