What is Rapid diagnosis of rabies is made with? and explain in detail?
Biopsy is taken from nape of neck, rabies virus present in hair follicle. Rabies-Lab Diagnosis Rabies Antigens or Nucleic Acids detection: Immunofluorescence or immunoperoxidase staining Biopsy specimen from skin of the neck at hairline Impression preparations of brain or cornea tissue Negri bodies in the brain-80% positivity -PCR test on brain tissue specimen Viral Isolation Tissue is inoculated intra-cerebrally into suckling mice Serology Serum / CSF anti-rabies Ab by immunofluorescence Animal observation