What is Anti-carcinogens are: (PGI Dec 2007) and explain in detail?
Ans: A (Carotenoids) Cancer Chemoprevention: Agents used Harrison 17th/488-89 # Premalignant lesions in the oropharyngeal area have responded to retinal/ a-tocopherol (vitamin E)Q, and selenium Q b carotene( a carotenoid) may decrease the incidence of lung, esophagus, and stomach cancer (in accordance with various trials, but the definite evidence is lacking)- CMDT09/1424 Nonsteroidal anti-inflammatory drugs (NSAIDs). such as piroxicam, sulindac, and aspirin, may prevent adenoma formation or cause regression of adenomatous polyps. Diets high in calcium lower colon cancer risk Atrial comparing tamoxifen Q with another selective estrogen receptor modulator, raloxifene, showed that raloxifene is comparable to tamoxifen in cancer prevention. FinasterideQ, a 5-a-reductase inhibitor is used in prostate cancer prevention. Selenium is being tested as a prostate cancerQ preventive based on laboratory studies, epidemiologic data, and a small randomized skin cancer prevention trial that showed a significantly decreased number of prostate cancers in men taking selenium