Thus the commission was awarded the year after the victory of the Christian fleet over the Turks in the Battle of Lepanto, won on 7 October 1571 thanks to the intercession of the Virgin Mary, because of which Pope Pius V instituted the feast of Our Lady of the Rosary. The painting shows the Virgin and Child between Saints Dominic and Catherine of Siena (the practice of reciting the Rosary was spread mainly by the Dominican order) and some bishops.
L’incarico fu quindi conferito l’anno successivo alla vittoria della flotta cristiana sui turchi nella battaglia di Lepanto, avvenuta il 7 ottobre 1571 grazie all’intercessione della Vergine, per la quale il Papa Pio V istituì la festa della Madonna del Rosario. L’opera raffigura la Madonna col Bambino, tra i Santi Domenico e Caterina (il Rosario fu diffuso principalmente dall’Ordine domenicano) e alcuni Vescovi.