This change in mental attitude is partly due to the religious crisis that was unleashed by the terrible "Black Death" of 1346, and partly to the different forms of research that were being experimented by other schools of painting, as, for example, in Siena.
Questo diverso atteggiamento mentale è dovuto in parte alla crisi religiosa scatenata dalla terribile "peste nera" del 1348, in parte dalle diverse ricerche compiute in quegli anni da altre scuole pittoriche, come quella senese.