Located in the French Pyrénées (Midi-Pyrénées region, Hautes-Pyrénées department, near Saint-Lary-Soulan and Barèges in the Néouvielle massif), the reserve lies to the east of the Pyrenees National Park. It lies in the municipal territories of Vielle-Aure (enclave), Saint-Lary-Soulan (enclave) and Aragnouet.