Born in Geraldine, Inglis began work as a professional mountaineer in 1979 as a search and rescue mountaineer for Aoraki / Mount Cook National Park. In 1982 Inglis and climbing partner Philip Doole were stuck in a snow cave on Aoraki / Mount Cook for 13 days due to an intense blizzard. The rescue of the two climbers was a major media event in New Zealand. Both men's legs became badly frost bitten while awaiting rescue. Following Inglis's rescue, both his legs were amputated 14 cm below the knee. He returned to Mt. Cook in 2002 and reached the summit successfully on 7 January of that year, after a previous attempt was thwarted by problems with his legs. The summit assault in January 2002 was documented by the film No Mean Feat: The Mark Inglis Story.