In 1851, Running Antelope was elected one of four shirt wearers of the Húŋkpapȟa. A shirt wearer served to intercede between the council and the headmen and akíčhita who carried out tribal policy and decisions. He was a brave warrior and accomplished diplomat. A great council with the Sioux was called at Fort Laramie and Fort Rice in 1868. Running Antelope signed the Treaty of 1868 at Fort Rice. It was often said that Running Antelope was the greatest orator of the Sioux Nation. He attended the Fort Laramie, Fort Rice and Fort Peck treaty councils. Under the influence of James McLaughlin, he became a dominant leader of the reservation Hunkpapa people at the Grand River Agency. He was enrolled in 1868 at Grand River Agency, later part of Standing Rock Reservation in North and South Dakota. After the allotment period. Running Antelope established a settlement of about sixty families in the Grand River valley and opened a store. In his later years, he regretted signing the 1868 Treaty and longed for the time when the Lakota were free, and realigned with Sitting Bull. Late in 1880, the followers of Sitting Bull began to return from exile in Canada and in the spring of 1881, Running Antelope was enlisted as a scout in the army to go to Fort Buford to escort Gall and his followers to Standing Rock.