The Afon Mawddach () is a river in Gwynedd, Wales, which has its source in a wide area north of Dduallt in Snowdonia. It is 28 miles (45 km) in length, and is much branched; many of the significant tributaries are of a similar size to the main river. The catchment area is bounded to the east by the Aran Fawddwy massif and to the west and north by the Harlech dome which forms a watershed just south of Llyn Trawsfynydd.