Established in mid-1942 as the 440th Bombardment Squadron; equipped with B-26 Marauder medium bombers. Trained in the Southeastern United States under III Bomber Command. Was deployed to North Africa in late 1942 as part of Twelfth Air Force, operated from desert airfields in Morocco, Algeria and Tunisia. The squadron attacked enemy railroads, airfields, harbor installations, and shipping along the Mediterranean Coast. Moved to Sicily and Italy and participated in the Italian Campaign, attacking targets in Italy supporting the Fifth Army advanced in the Cassino and Anzio areas. The squadron later attacked targets in the Rome area, then moved to Corsica to support the Allied landings in Southern France. Remaining in Corsica, the squadron later hit railroad bridges in Northern Italy and late in the year attacked railroad lines through the Brenner Pass that connected Germany and Austria with Italy.