The Serranía del Perijá, Cordillera de Perijá or Sierra de Perijá is a mountain range, an extension of the eastern Andean branch (Cordillera Oriental), in northern South America, between Colombia and Venezuela, ending further north in the Guajira Desert, a total distance of about . It separates the Maracaibo Basin from the Cesar-Ranchería Basin. Some of the area has been considered as a Flora and Fauna Sanctuary.