Hätzingen is located on the Hauptstrasse 17, which runs the length of the canton of Glarus before climbing the Klausen Pass into the canton of Uri, as well as on the Weesen to Linthal railway line that parallels the main road and the Linth river through Glarus. The high alpine Klausen Pass is normally only open to traffic between June and September, and for the rest of the year the road and railway up the valley form the only access to the village. The village is served by Luchsingen-Hätzingen railway station, which is served by the hourly Zürich S-Bahn service S25 between Linthal and Zurich.