Zabriskie's 2006 season started out well, with a strong 2nd-place finish in the February stage race Amgen Tour of California, 29 seconds after the winner, countryman Floyd Landis. He was initially placed 3rd in the April stage race Ford Tour de Georgia, but as he lost time to the favourite riders on the Brasstown Bald mountain stage, he finished 6th place overall. Dave Zabriskie won two time trials in the Dauphiné Libéré in May, beating Floyd Landis in the prologue by two seconds, and winning Stage 3 by 53 seconds, again ahead of Landis, further proving Zabriskie's outstanding time trialing skills. Following several mountain stages, including a ride up the Mont Ventoux, Zabriskie finished the race in 32nd place, behind winner Levi Leipheimer. Upon completing the 2006 Tour de France in 74th place, Zabriskie became the second American behind Christian Vande Velde to finish all three Grand Tours.