Pike of Blisco stands on the complex ridge of high ground descending south-eastward from the Scafell massif. The ridge incorporates Esk Pike, Bow Fell, Crinkle Crags and Cold Pike before turning sharply north-eastward to Pike of Blisco; it then makes a further abrupt northerly diversion around Blea Tarn to connect to Lingmoor Fell. To the north of Pike of Blisco is the Oxendale branch of Great Langdale, while Little Langdale stands to the south east. The two valleys drain eastward, joining beyond Lingmoor Fell. To the south of Pike of Blisco is the 393 m (1,290 ft) summit of Wrynose Pass, which links Little Langdale with the Duddon Valley, and beyond the pass lies Swirl How and the Coniston Fells.