Idaho State Highway 28 (Railroad Street) passes through the center of Leadore, leading northwest to Salmon, the county seat, and southeast to Interstate 15 at Sage Junction. Idaho State Highway 29 leads northeast from Leadore to the Montana state line at Bannock Pass on the Continental Divide. Montana Secondary Highway 324 continues northeast from Bannock Pass to join Interstate 15 at Clark Canyon Dam, northeast of Leadore.