Yeshaq's reign was marked by a revolt of the Beta Israel. In response, the Emperor marched into Wegera, where he defeated the rebels at Kossoge some north of Gondar, thereby ending the revolt. He also had the church Debre Yeshaq built there to commemorate his victory. Yeshaq also invaded the Shanqella region beyond Agawmeder, and to the southeast he fought against the sons of Sa'ad ad-Din II who returned from exile in the Arabian Peninsula.