Great Missenden is an affluent village with approximately 2,000 residents in the Misbourne Valley in the Chiltern Hills in Buckinghamshire, England, situated between the towns of Amersham and Wendover, with direct rail connections to London Marylebone. It closely adjoins the villages of Little Kingshill, Little Missenden and the larger village Prestwood. The narrow and historic High Street is bypassed by the main A413 London to Aylesbury Road. It is located in the heart of The Chilterns Area of Outstanding Natural Beauty. The source of the Misbourne is to be found just north of the village, although the upper reach of the river runs only in winter and the perennial head is in Little Missenden. The village is now best known as home to the late Roald Dahl, the world-famous author.