After Breezewood, I-76 continues along the turnpike, heading northeast across Rays Hill into Fulton County. The turnpike continues east across Sideling Hill, before reaching an interchange with US 522 in Fort Littleton. After this interchange the highway parallels US 522 before curving east into Huntingdon County. The turnpike goes under Tuscarora Mountain through the Tuscarora Mountain Tunnel, entering Franklin County. It then curves northeast into a valley to the exit for PA 75 in Willow Hill.