Unlike the many well known passes that lie on the spine of the Cascades, Blewett Pass lies on the divide between the Wenatchee River to the north and the Yakima River to the south. The highway over the pass connects Interstate 90 (I-90) between Seattle and Ellensburg, Washington with US 2 between Monroe and Wenatchee. The route from Seattle to Wenatchee over Snoqualmie Pass and Blewett Pass is a reasonable alternative to the more northerly route over Stevens Pass.