Centrolene scirtetes, the Tandayapa giant glass frog, is a species of frog in the family Centrolenidae. It is only known from two locations on the Pacific versant of the Andes, its type locality near Tandayapa in the Pichincha Province of northern Ecuador, and from the Colombian Massif in the Nariño Department of southern Colombia. It might be conspecific with Centrolene lynchi.