Uropeltis rajendrani is a fossorial snake, that is mostly nocturnal, feeding presumably on soft-bodied worms. It was described from the Bodha Malai hills near Panamarathupatti town. This species has previously been sighted from Semmedu, Solakkadu, Kuzhivalavu, Seekuparai, Thenur Nadu, Selur Nadu, Gundur Nadu settlements of Kolli Hills. Uropeltis rajendrani inhabits moist forest floor and under the humus-rich top soil, in humid forests.