At the crossroads of the Maurienne and Tarentaise valleys, not far from the Col de l'Iseran, the Grande Aiguille Rousse lies in the region where the waters that flow through these great alpine valleys diverge. It is part of a series of mountains that define the frontier between Savoie and the Italian regions of Piedmont and the Aosta Valley, including such peaks as the Pointe de Ronce, the Bessanèse, the Levanna, and the Pointe de la Galise. The Grande Aiguille Rousse is shared by the communes of Val-d'Isère and Bonneval-sur-Arc.