The Everest Marathon is open to runners aged 18 or above from all over the world, as long as they fulfill a certain set of criteria. A medical checkup certificate from authorized health professionals that certifies the runner's ability to withstand high altitude conditions is mandatory while submitting the application form. Considering the high altitude conditions of the race, runners are also advised by the organizers to take a minimum of 1-5 days for acclimatization. All runners are also compulsorily required to have a valid health insurance before participation. The marathon has a participation limit of around 250 runners across all categories.