The Saale originates on the slope of the Großer Waldstein mountain near Zell in the Fichtelgebirge in Upper Franconia (Bavaria), at an elevation of . It pursues a winding course in a northern direction, and after passing the manufacturing town of Hof, enters Thuringia. It flows amid well-wooded low mountains of the Thuringian Forest until it reaches the valley of Saalfeld. After leaving Saalfeld the Saale reaches Rudolstadt. Here it receives the waters of the Schwarza, in whose valley lies the ruined castle of Schwarzburg, the ancestral seat of the formerly ruling House of Schwarzburg.