The western end of the Alpine Lakes Wilderness is accessible via the Middle Fork of the Snoqualmie River northeast of North Bend, Washington. Snoqualmie Pass provides access to the southwestern end of the wilderness. Salmon La Sac north of Roslyn, Washington is a hub for trailheads and U.S. Forest Service roads providing entry into the southern and central regions. The Stuart Range on the eastern end of the wilderness is accessible by Ingalls Creek on the south and Icicle Creek, near Leavenworth, Washington, on the north. North of Icicle Creek are the Chiwaukum Mountains which stretch northwards to Highway 2. The northern parts of the Alpine Lakes are accessible from Highway 2 and Stevens Pass.