The team began the Giro with a poor team time trial, finishing 17th of 23 teams, immediately putting Kreuziger 50 seconds off the race lead. Kreuziger made each of the day's selections in stage 5, a hilly stage with numerous sectors of unpaved or 'white' roads, and finished with the race's top riders eight seconds back of the day's winner and new race leader Pieter Weening. This result moved Kreuziger up 42 places, from 70th to 18th, even though his time gap to the race leader remained close to the same. Kreuziger took one of the time bonuses two days later on Montevergine di Mercogliano, as the race's top riders narrowly missed taking back the last breakaway rider Bart De Clercq on the Giro's first summit finish. While the Belgian won the stage, Kreuziger's third-place ride moved him further up the classification, to 14th. Kreuziger, like the rest of the field, was greatly outclassed by Alberto Contador on Mount Etna in stage 9, but despite finishing 50 seconds back he vaulted even higher in the standings, entering the top ten overall for the first time, at seventh. He also gained the white jersey for best young rider after this stage. He held that position in stage 11, which unexpectedly became a stage for the overall classification riders despite Contador's hints that he may cede his pink jersey on this day. With Michele Scarponi's Lampre-ISD leading a strong chase, Kreuziger finished sixth on the day, amongst the race's top riders, to remain seventh overall.