Phahonyothin Road, part of the AH2 Highway system, crosses the Phi Pan Nam Range area from north to south, between Tak and Chiang Rai. There are two railway tunnels of the Northern Line across the Phi Pan Nam mountains. Both are on the south side of the range: the 130.2 m Huai Mae Lan Tunnel in Phrae Province and the 362.4 m Khao Phlueng Tunnel in Uttaradit and Phrae Provinces.