The first ascent of Piz Scerscen was by Paul Güssfeldt, Hans Grass and Caspar Capat on 13 September 1877 via the north-west spur, descending the same way. This is the well-known Eisnase route, involving a 100-metre ice pitch of between 60-70°, although its precise length and steepness are debated. This was the route followed by Walter Risch on the first solo ascent of the mountain in 1924. The first ascent of the north-west face was by Christian Klucker and L. Norman-Neruda on 9 July 1890.