Beyond US 30, I-70 heads south and becomes a four-lane limited-access freeway that once again conforms to modern Interstate standards. The median widens, before the freeway crosses over its preceding carriageways and under the Pennsylvania Turnpike. Shortly past the turnpike underpass, there is an interchange with South Breezewood Road before I-70 reverse curves to cross Rays Hill, crossing into Fulton County, and coming to a pair of right-in/right-out ramps with the southern terminus of PA 915 in the unincorporated village of Crystal Spring, in Brush Creek Township. The freeway continues through a valley of farmland and comes to an eastbound rest area on the western slope of Town Hill, which the highway crosses at an oblique angle. In the middle of the mountain crossing, I-70 has another pair of right-in/right-out ramps with the northern terminus of PA 643, and then descends along the length of its eastern slope into another rural valley. Within this valley, the freeway enters Union Township, turns generally more southeast and interchanges with the northern terminus of PA 731, east of the unincorporated village of Amaranth.