The Serranía de Macuira measures around in length and is circa wide, at approximately from the Caribbean sea. The range is composed of three mountain massifs that are interconnected; the highest being Cerro Paluou (), Cerro de Jibome () covering a total area of . The area is home to numerous species of fauna and flora and due to its relatively high humidity caused by the trade winds and its proximity to the Caribbean sea it presents a forest of dwarf trees and cloud forests. The frog Allobates wayuu is only known from the Serranía de Macuira.