After entering Craig County, SR 42 passes the communities of Huffman, Simmonsville, and Sinking Creek, the creek with that name ending soon after. SR 42 then crosses a summit at 2704 feet (824 m) and begins to parallel Meadow Creek past Looney to Meadow Creek Falls, where it reaches its first twisty section. It descends through a gap between Sinking Creek Mountain and Johns Creek Mountain and down the slopes of Johns Creek Mountain into the town of New Castle, where it ends again at State Route 311. This descent takes it from 2570 feet (783 m) at Looney down to 1310 feet (399 m) in New Castle.