The highway departs the Colorado River near Dotsero, the name given to the railroad separation for the two primary mountain crossings, the original via Tennessee Pass/Royal Gorge and the newer and shorter Moffat Tunnel route. I-70 uses a separate route between the two rail corridors. From this junction I-70 follows the Eagle River toward Vail Pass, at an elevation of . In this canyon I-70 reaches the western terminus of U.S. Highway 24, which meanders through the Rockies before rejoining I-70. US 24 is known as the Highway of the Fourteeners, from the concentration of mountains exceeding along the highway corridor.