The Aspy River () is a river on northeastern Cape Breton Island which rises in the Cape Breton Highlands and empties into Aspy Bay. The North Aspy follows the ancient Aspy Fault which extends for 40 km inland from the coast and extends along the upper section of the northeast Margaree River. This geological fault is thought to be a part of the Cabot Fault (Newfoundland)/ Great Glen Fault (Scotland) system of Avalonia.