The Desaguadero River (, ]) is a river in Argentina. Originating near the Tipas volcano in La Rioja at about elevation, the river is known in its upper reaches as the Bermejo or Vinchina. In its lower reaches it is also known as the Salado. It joins the Colorado River in La Pampa Province near Pichi Mahuida. The Desaguadero River has a total length of and its drainage basin is about .