Asplenium resiliens is found in the southern United States, Mexico, Hispaniola, Jamaica, Guatemala, and South America from Colombia and Venezuela south to northern Argentina, Uruguay, and Brazil. Within the United States, it is found from Florida west to Arizona and southern Nevada and north to south-central Pennsylvania. It is found throughout most of Mexico, but is most abundant in the northeast, in Nuevo León and Coahuila. In Guatemala, it is known from the western departments of Huehuetenango, El Quiché, and Sololá. In Argentina, its distribution follows the arc of the mountains from Jujuy Province southward to the Sierra de la Ventana in Buenos Aires Province; it is also known from Mendoza Province, in the west of the country, from the departments of Las Heras and Luján de Cuyo.