The most notable bearers of the name are the Supersaxo auf der Flüe of Naters. They are descended from the Manegoldi, a family of episcopal ministeriales originally of Ernen. They renamed themselves ab der Flue or de Saxo in c. 1340 (Rudolph Super Saxum) after their seat in Naters, the castle Uff der Flüe. After 1352, the castle was occupied by the castellanus of Naters and it intermittently served as residence of the prince-bishops of Sion in the 15th and 16th centuries. Three members of the family served as prince-bishops of Sion.