Patterns of increased endemism at higher elevations on both islands and continents have been documented on a global level. As topographical elevation increases, species become isolated from one another; often constricted to graded zones. This isolation on mountain top islands creates barriers to gene flow, encouraging allopatric speciation, and generating the formation of endemic species. Mountain building (orogeny) is directly correlated with—and directly affects biodiversity. The formation of the Himalayan mountains and the Qinghai-Tibetan Plateau for example have driven the speciation and diversification of numerous plants and animals such as Lepisorus ferns; glyptosternoid fishes (Sisoridae); and the Rana chensinensis species complex. Uplift has also driven vicariant speciation in Macowania daisies in South Africa's Drakensberg mountains, along with Dendrocincla woodcreepers in the South American Andes. The Laramide orogeny during the Late Cretaceous even caused vicariant speciation and radiations of dinosaurs in North America.