By the 2nd century BC, Loulan had grown to dominate the region around the Tarim Basin. Archeological evidence suggests a sophisticated culture with major importance in the trade between central Asia and India. Southern merchants passed through mountain ranges such as the Karakoram, Himalayas and Hindu Kush as far north as the Taklamakan desert, to important trading cities like Loulan and its commercial rival Niya. This is evidenced by graffiti carved on stones along the route in Indic scripts such as Kharosti and Brahmi, while there are depictions of Siddhartha Gautama (evidencing the spread of Buddhism along the trade route). From here,