The range spans about , running in a generally northwest-southeast direction. It is bordered to the north by Interstate 10 and the town of Desert Center, and to the south by the Bradshaw Trail and the Chocolate Mountains Aerial Gunnery Range. The highest point is Black Butte, elevation . The Chuckwalla Range is divided from the Little Chuckwalla Range by Graham Pass. The Orocopia Mountains are to the west, and Joshua Tree National Park is to the northwest.