The most popular base from which to begin ascent of Mount Bierstadt is Guanella Pass, located to the west. From Guanella Pass it is approximately a hike, with a climb of . The trail descends slightly into the fairly level marshlands surrounding Scott Gomer Creek before reaching Bierstadt's western slopes. On the rocky upper regions of the mountain the route of the trail is marked by a series of cairns. The trail levels about below the summit at saddle point before beginning the final ascent. Alternative trails cover the eastern slopes for longer hikes.