Once on island, the falls can be accessed by Route 580. At the milepost 6, 580 heads inland for three miles (5 km). Route 580 is called Kuamoʻo Road at this point and it is to the ʻŌpaekaʻa Falls parking lot and overlook. Route 580 goes through a notch in the ridge that the Wailua River has eroded. There are no state-maintained trails to either the top or the bottom of the waterfall from the Kuamoʻo Road overlook.