Kinyongia matschiei, common name giant monkey-tailed east Usambara two-horned chameleon, giant east Usambara blade-horned chameleon, and Matschie's two-horned chameleon, is a species of chameleon from the East Usambara Mountains in Tanzania. It was formerly confused with K. fischeri, which is not found in the range of K. matschiei.