Sulphide Glacier is in North Cascades National Park in the U.S. state of Washington, on the south slopes of Mount Shuksan. Descending from the summit tower of Mount Shuksan, it is connected to Crystal Glacier to the east. Sulphide Glacier descends from . Sulphide Glacier is along the route taken when Mount Shuksan was first climbed in 1906. Both Sulphide and Crystal Glaciers have a series of high cascades which are collectively referred to as Sulphide Basin Falls. Below these cascades lies Sulphide Lake, which empties over Sulphide Creek Falls, one of the highest waterfalls in North America with a nearly drop.