The Serranía de Macuira mountain range is located to the northwest of the Guajira Peninsula occupying an area of , of which are contained within the Macuira National Park. The mountain range is an isolated ecosystem in the middle of the La Guajira Desert, near the Caribbean sea, between the villages of Nazareth, Ichipa and Tawara. The mountain range works as a barrier to humid trade winds, which blow from the northeast.