The hospice in All'Acqua was the starting point to two famous mountain crossings: the Nufenen Pass, which leads to Ulrichen in the Upper Valais, and the Passo di San Giacomo, which leads to the Italian Formazza valley. The Hospice of Valdolgia or St. Nicholas on the Passo di San Giacomo was a second station in the old mule track. Due to the steep slopes of Bedretto Valley, avalanches often hit the villages. The avalanche in 1863, destroyed half the village and killed 29 people, and the one in 1749 killed 13. In winter, the valley is often cut off and the connection of villages to each other and with Airolo may be interrupted for days. With the construction of avalanche barriers, the situation has improved. The road between Airolo and Bedretto opened in 1924, was extended in 1932 to Ronco then in 1964 extended beyond Nufenen. The valley is also today still fairly isolated and without a constant connection with Valais, since a rail project to connect the valley to the Furka Oberalp Bahn as part of the Furka Base Tunnel project failed. Historically, the scarce resources of the valley (cattle, dairy farming and cultivation of potatoes and rye) were insufficient to feed all of the inhabitants. So they were forced to seasonal migrate abroad (mainly in Italy and France) seeking work as chestnut roasters, waitresses or domestic servants. Since the seasonal migration ceased at the end of World War II, the valley has depopulated more rapidly. The decline of the permanent resident population is offset in the summer months by the return of locals and offset in the winter by the influx of tourists and holiday guests.