Titanoboa inhabited the first recorded tropical forest in South America. It shared its ecosystem with large Crocodylomorpha and large turtles. The paleogeography of the Late Paleocene was a sheltered paralic (coastal) swamp area, sheltered by the emerging later Guajira hills in the west and the slowly rising present-day Serranía del Perijá in the east, with an open connection to the proto-Caribbean in the north. In this environment the tropical aquatic ferns of the genus Salvinia flourished, as evidenced by fossils found in Cerrejón, the Bogotá Formation and the Palermo Formation.