SR 24 crosses the Columbia River on the Vernita Bridge, a steel truss bridge downriver from the Priest Rapids Dam. On the north side of the bridge in Grant County, the highway intersects SR 243, which travels along the Columbia River towards Mattawa and Vantage. SR 23 turns northeast and follows the south wall of the Wahluke Slope before traveling due east across the Saddle Mountain National Wildlife Refuge and into Adams County. The highway leaves the Hanford Reach National Monument and forms the boundary between Adams and Franklin counties for several miles, briefly turning to cross a section of the Saddle Mountains. Near the former Othello Air Force Station, SR 24 turns north and follows Radar Road through farmland on the outskirts of Othello. After entering Othello, the highway becomes Broadway Avenue and continues through an industrial area before terminating at an underpass with SR 26. The two highways are connected via an extension of 1st Avenue on both sides of the underpass.