The Huasna River is a stream in the Central Coast region of California, and is a tributary of the Cuyama River. It is formed by the confluence of Trout Creek and Stony Creek, which originate along the crest of the Santa Lucia Range in the Los Padres National Forest. It flows south, past the community of Huasna and the Huasna Valley before reaching Twitchell Reservoir, which is created by a dam along the Cuyama River.