The first win of Pinot's 2017 campaign came at the Vuelta a Andalucía, as he rode past Alberto Contador in the final hundred meters. Pinot finished the race in 3rd position overall, and went on to ride the Strade Bianche in which he finished 9th. Pinot confirmed his form was great when he finished 3rd overall at the Tirreno-Adriatico a week later. As Pinot was targeting the 100th edition of the Giro d'Italia in 2017, his last preparation race was the Tour of the Alps. He finished in top 5 on all 5 stages, including a stage win on the final stage to Trento, and also had the leaders jersey on stage 3. Pinot finished 2nd place overall, and looked strong for the Giro. He started the Giro d'Italia a 4th place on Mount Etna following the other general classification contenders. Finishing 2nd on stage 9 to Blockhaus, Pinot advanced to 2nd place in the general classification. However on stage 10 which was a 39.8 kilometer long Time trial, Pinot dropped to 4th place. As Pinot won stage 20 of the race, he moved up to 3rd place overall before the Time trial on stage 21. Having a 43 second disadvantage to Nairo Quintana, Pinot was only the underdog going into the final stage. He finished 28th on the stage, and dropped to 4th place overall just 37 seconds behind Vincenzo Nibali.