Pristimantis simoteriscus is a species of frogs in the family Craugastoridae. It is endemic to Colombia and occurs in the Cordillera Central in the Tolima, Quindío, and Caldas Departments. There is also an unconfirmed record from the Valle del Cauca Department. The specific name simoteriscus is diminutive of simoterus, chosen because adult P. simoteriscus resemble juvenile individuals of Pristimantis simoterus.