The Warm Springs River is a tributary of the Deschutes River in north-central Oregon in the United States. It flows generally southeast along the east side of the Cascade Range. The watershed is approximately between Mount Jefferson and Timothy Lake, and the northwestern and southwestern boundaries of the Warm Springs Indian Reservation coincide with the watershed. The headwaters are less than from the Wasco County-Clackamas County boundary (which follows the Cascade crest). The river flows generally eastward, with occasional diagonals southeast or northeast. It joins the Deschutes River at river mile 83.7 (134.7 km upstream from the mouth of the Deschutes).