The museum hosts extensive collections of Greek and Roman antiquities. Their core is from the Farnese Collection, which includes a collection of engraved gems (including the Farnese Cup, a Ptolemaic bowl made of sardonyx agate and the most famous piece in the Treasure of the Magnificent, and is founded upon gems collected by Cosimo de' Medici and Lorenzo il Magnifico in the 15th century) and the Farnese Marbles. Among the notable works found in the museum are the Herculaneum papyri, carbonized by the eruption of Mount Vesuvius, found after 1752 in Villa of the Papyri.