US 395 is concurrent with I-82 as it enters Washington on the Umatilla Bridge, a set of bridges that cross the Columbia River north of Umatilla, Oregon. The freeway carrying both highways travels north over the Fallbridge Subdivision of the BNSF Railway system and through an interchange with SR 14 east of Plymouth before traversing Fourmile Canyon. I-82 and US 395 turn north at Bofer Canyon and travel across irrigated farmland before crossing over the Horse Heaven Hills and intersecting SR 397. At its next exit in southwestern Kennewick, I-82 splits from US 395 in a trumpet interchange and heads northwest towards the Yakima River Valley. US 395 continues northeasterly into Kennewick, running as a four-lane divided highway with several signalized intersections.