Mearns's squirrel is known from only three sites in the Sierra de San Pedro Mártir in Baja California, Mexico. The region is surrounded by areas of chaparral and desert, isolating the tree squirrel from its closest relatives elsewhere, and indicating that it is likely a relict population isolated by forest fragmentation during the Pleistocene. The three sites all consist of pine and fir forests at altitudes of , and cover an area of no more than .