The Mosisberg is the second northernmost of a line of four peaks that exceed 600 m. To the north is the Eschkopf (608.3 m), to the south are the Hortenkopf (606.2 m) and the Weißenberg (ca. 610 m) The Palatine Watershed between the Moselle/Middle Rhine (west) and Upper Rhine (east) runs over the Eschkopf, Mosisberg and Hortenkopf.