The Ligurian Apennines border the Ligurian Sea in the Gulf of Genoa, from about Savona below the upper Bormida River valley to about La Spezia (La Cisa pass) below the upper Magra River valley. The range follows the Gulf of Genoa separating it from the upper Po Valley. The northwestern border follows the line of the Bormida River to Acqui Terme. There the river continues northeast to Alessandria in the Po Valley, but the mountains bend away to the southeast.