The creek begins at an unnamed confluence in the Regional District of Fraser-Fort George, heads southwest under British Columbia Highway 5 and the Canadian National Railway transcontinental main line (used by freight traffic and the Via Rail Canadian train), and turns southeast. The highway and railway line follow the Albreda River valley, crossing several times, for the balance of its course. The river passes into Thompson-Nicola Regional District at the locality of Albreda, flows through Albreda Lake, turns south, and reaches its mouth at the North Thompson River, at the railway point of Goswell, towered over by Mount Albreda, part of the Monashee Mountains and the source of the tributary Clemina Creek and Dora Creek, to the east. The North Thompson River flows via the Thompson River and the Fraser River to the Pacific Ocean.