Nibali and Wiggins entered the Giro d'Italia as the two favourites for overall victory. Nibali took the leader's pink jersey () on stage eight after finishing fourth in the time trial won by Alex Dowsett, conceding only 11 seconds to Wiggins. On stage ten, the first mountain top finish, Nibali finished third behind Rigoberto Urán to extend his lead over second placed Evans to 41 seconds. The rest of the race was severely affected by poor weather conditions. Nibali put further time into his rivals on stage 14, finishing on , as he and Mauro Santambrogio rode away in freezing conditions, with Nibali allowing Santambrogio to take the stage win; after the disqualification of Santambrogio, due to a positive test for EPO, the stage victory was retroactively awarded to Nibali. Nibali won stage 18, a mountain time trial, by 58 seconds from Samuel Sánchez, to extend his lead over Evans and Urán to over four minutes. The following stage, scheduled to be the queen stage of the race, had to be cancelled due to snow. Stage 20, the final mountain stage, also saw heavy snow, as Nibali attacked on the final climb to Tre Cime di Lavaredo to win the stage by 17 seconds from Fabio Duarte, with Urán a further two seconds back. Nibali also moved into the lead in the points classification. Nibali safely negotiated the final stage to Brescia to win the Giro by four minutes 43 seconds over Urán, his second Grand tour overall victory. However, as Mark Cavendish collected all the intermediate sprints before winning the final stage, Nibali finished second to Cavendish in the points classification.