The Cascapédia River is a river in the Gaspé Peninsula of Quebec, Canada, which has its source at Lake Cascapedia, fed by streams of the Chic-Choc Mountains, and empties into Cascapedia Bay (Baie de la Cascapédia), a small bay of Chaleur Bay. The river is about long. At times, it is also called Grand Cascapédia River to differentiate it from the Little Cascapédia River which empties into the same bay just to the east.