The Löhne-Rheine railway is a two-track, continuously electrified railway main line from Löhne in the German state of North Rhine-Westphalia via Osnabrück in Lower Saxony to Rheine in North Rhine-Westphalia. It runs parallel to the Wiehen Hills to the north and to the Teutoburg Forest to the south. The line opened in 1855 and 1856 and was one of the oldest railways in Germany.