Neuhütten lies in the Main-Spessart district in the Würzburg region. I is located in the Mittelgebirge Spessart. The municipal territory mostly lies in the valley of Grimmenwiesenbach a tributary of the Lohrbach but stretches into the valley of the Lohrbach river itself, which passes to the north. The highest elevation of the municipality is to the southeast, on the slopes of Hengstkopf.