Rosebank is located on the lower eastern slope of Devil's Peak, stretching down to the Liesbeeck River, and on the other side of the river up to the edge of Rondebosch Common. On the west it is bounded by the M3 freeway. The historic Mostert's Mill is located just next to the freeway. Much of the land between the M3 and Main Road, which runs north-south through the suburb, belongs to the University of Cape Town and is used for residences and sports fields. The area around Main Road is a mixture of university residences, shops and blocks of flats.