State Route 133 (SR 133) is a state highway in the U.S. state of California, serving as an urban route in Orange County. It connects SR 1 in Laguna Beach through the San Joaquin Hills with several freeways in Irvine, ending at the SR 241, a toll road in the latter city. It is built as an expressway from SR 73 to Laguna Canyon Road (just south of I-405 in Irvine), and past this, SR 133 is a freeway (the Laguna Freeway) to I-5, and a tollway (part of the Eastern Toll Road) to SR 241 near the Santa Ana Mountains.