The range runs from Peebles in the Scottish Borders, in a north easterly direction to Tynehead near the A7 road in Midlothian. The highest point of the Moorfoot Hills is Windlestraw Law, at 659 metres (2162 feet). Other significant hills include Blackhope Scar (651m), Dewar Hill, Garvald Law, Rough Moss (601m) and Peatrig Hill (454m). Parts of the Moorfoot Hills are designated a Special Area of Conservation.