The expressway commences at a junction with the Jōban Expressway in Iwaki, Fukushima and follows a northwesterly course to the city of Kōriyama, where it intersects with the Tōhoku Expressway. The expressway continues its course through the historic Aizu region, with Mount Bandai viewable to the north and Lake Inawashiro viewable to the south. The route then enters Niigata Prefecture and eventually terminates at a junction in Niigata City with the Hokuriku Expressway and Nihonkai-Tōhoku Expressway.