The vegetation in the Pueblo Mountains is dominated by big sagebrush and desert grasses. Common grass species include Idaho fescue, bluebunch wheatgrass, cheatgrass, Thurber's needlegrass, mountain brome, Sandberg's bluegrass, and bottlebrush squirreltail. There are high mountain meadows around springs and narrow riparian greenways that follow the year-round streams. Some greenway areas have cottonwood, aspen, and willow groves. Meadow and high-desert wildflowers found in the Pueblo Mountains include larkspur, Indian paintbrush, cinquefoil, shooting star, columbines, monkey flower, asters, buttercups, low pussytoe, lupin, arrowleaf balsamroot, penstemon, agoseris, draba, mariposa lily, sego lilies, evening primrose, and iris.