Catania has one of the four laboratories of the Istituto Nazionale di Fisica Nucleare (National Institute for Nuclear Physics) in which there is a cyclotron that uses protons both for nuclear physics experiments and for particle therapy to treat cancer (proton therapy). Noto has one of the largest radio telescopes in Italy that performs geodetic and astronomical observations. There are observatories in Palermo and Catania, managed by the Istituto Nazionale di Astrofisica (National Institute for Astrophysics). In the Observatory of Palermo the astronomer Giuseppe Piazzi discovered the first and the largest asteroid to be identified Ceres (today considered a dwarf planet) on 1 January 1801; Catania has two observatories, one of which is situated on Mount Etna at .