Like most of the Smokies crest, Mount Collins is situated along the Tennessee-North Carolina border, with Sevier County to the north and Swain County to the south. The mountain rises approximately above its southeastern base near Bryson City and just over above its northwestern base near Meigs Post Prong . The mountain is the 25th-highest mountain in the Eastern United States, the 7th-highest in Tennessee, and the 10th-highest in the Great Smoky Mountains National Park.