Panaitoliko () is a mountain range in the northeastern part of Aetolia-Acarnania and southwestern Evrytania, in western Greece. Its highest summit, Kyra Vgena (), is the highest point of Aetolia-Acarnania at 1,924 m. Its length is approximately 25 km long from east to west and its width is approximately 15 km wide. The nearest mountains are Kaliakouda to the northeast, the mountains of Nafpaktia to the southeast and Valtou to the northwest. Lake Trichonida lies to the south. The Panaitoliko extends from the Acheloos valley in the northwest to the Evinos valley in the east. There are forests in the lower areas, and grasslands in the higher elevations.