In spring 1921, the regiment was transferred to the Asia Minor front, disembarking at Mudanya on 17 March. The Evzones were quickly deployed to the area of Bursa, where itheir arrival thwarted a planned uprising by the Turkish population. The regiment took over the front sector around Tsongara, as well as conducting anti-guerrilla operations in the mountainous area of Uludağ. On 22 April, the regiment was withdrawn to be redeployed to Smyrna, being replaced by the 12th Infantry Regiment. After a three-day stay for recuperation in the city, on 1 May the regiment was moved by train southeast, to take over the Maeander River-Buldan sector.