The neuropharmacology of sleep paralysis hallucinations serotonin 2A activation and a novel therapeutic drug.
Sleep paralysis is a state of involuntary immobility occurring at sleep onset or offset, often accompanied by uncanny ghost-like hallucinations and extreme fear reactions. I provide here a neuropharmacological account for these hallucinatory experiences by evoking the role of the serotonin 2A receptor (5-HT