Designer benzodiazepines an update.
Designer benzodiazepines (DBs) are a subclass of novel psychoactive substances (NPS). DBs mimic the properties of approved and prescribed benzodiazepines. A systematic search of literature on DB classification, structure-activity relationships, pharmacologic properties, and adverse effects. The prevalence of DB use has increased substantially over the last decade. All DBs are full-agonist ligands at the gamma-aminobutyric acid type A-benzodiazepine (GABA