Natural Products for the Treatment of Pain Chemistry and Pharmacology of Salvinorin A, Mitragynine, and Collybolide.
Pain remains a very pervasive problem throughout medicine. Classical pain management is achieved through the use of opiates belonging to the mu opioid receptor (MOR) class, which have significant side effects that hinder their utility. Pharmacologists have been trying to develop opioids devoid of side effects since the isolation of morphine from