Isoform selectivity of harmine-conjugated 1,2,3-triazoles against human monoamine oxidase.
There is little information available on the monoamine oxidase isoform selectivity of N-alkyl harmine analogs, which exhibit a myriad of activities including MAO-A, DYRK1A and cytotoxicity to several select cancer cell lines. Compounds 3e and 4c exhibited an IC