The behavioral pharmacology and therapeutic potential of lorcaserin for substance use disorders.
Substance abuse is serious public health problem for which there are few effective pharmacotherapies. Traditional strategies for drug development have focused on antagonists to block the abuse-related effects of a drug at its site of action, and agonists to replacemimic the effects of the abused substance. However, recent efforts have targeted receptors, such as serotonin (5-HT)