what is the difference between widal test and typhidot test
Typhidot
title: Widal test text: the diagnosis of typhoid fever. As with all serological tests, the rise in antibody levels needed to perform the diagnosis takes 7–14 days, which limits its applicability in early diagnosis. Other means of diagnosing "Salmonella typhi" (and "paratyphi") include cultures of blood, urine and faeces. These organisms produce HS from thiosulfate and can be identified easily on differential media such as bismuth sulfite agar. 2-mercaptoethanol is often added to the Widal test. This agent more easily denatures the IgM class of antibodies, so if a decrease in the titer is seen after using this agent, it means that the contribution title: Widal test text: the titer (e.g., from 1:40 to 1:640) in the course of the infection, or a conversion from an IgM reaction to an IgG reaction of at least the same titer, would be consistent with a typhoid infection. A new serological test called the Tubex test is neither superior nor better performing than the Widal test. Therefore, Tubex test is not recommended for diagnosis of typhoid fever. Widal test In 1896 and named after its inventor, Georges-Fernand Widal, is a presumptive serological test for enteric fever or undulant fever whereby bacteria causing typhoid and malaria fever(caused by protozoa) are mixed with title: Typhidot text: a detailed Widal test can tell the titres of specific antibodies. However both tests lack sensitivity and specificity. The Widal test is losing its value as it is labor-intensive and time-consuming.It is an immunochromatographic test. Typhidot Typhidot is a medical test consisting of a dot ELISA kit that detects IgM and IgG antibodies against the outer membrane protein (OMP) of the Salmonella typhi. The typhidot test becomes positive within 2–3 days of infection and separately identifies IgM and IgG antibodies. The test is based on the presence of specific IgM and IgG antibodies to a specific 50Kd OMP antigen, which title: Widal test text: of IgM has been removed leaving the IgG component. This differentiation of antibody classes is important as it allows for the distinction of a recent (IgM) from an old infection (IgG). The Widal test is positive if TO antigen titer is more than 1:160 in an active infection, or if TH antigen titer is more than 1:160 in past infection or in immunized persons. A single Widal test is of little clinical relevance due to the high number of cross-reacting infections, including malaria. If no other tests (either bacteriologic culture or more specific serology) are available, a fourfold increase in title: Widal test text: Widal test In 1896 and named after its inventor, Georges-Fernand Widal, is a presumptive serological test for enteric fever or undulant fever whereby bacteria causing typhoid and malaria fever(caused by protozoa) are mixed with a serum containing specific antibodies obtained from an infected individual. In cases of "Salmonella" infection, it is a demonstration of the presence of O-soma false-positive result. Test results need to be interpreted carefully to account for any history of enteric fever, typhoid vaccination, and the general level of antibodies in the populations in endemic areas of the world. Typhidot is the other test used to ascertain