when was the problem of cfc's discovered
late 1970s 1974 1973 1970s
title: Environmental policy of the United States text: from the sun. Chlorofluorocarbons (CFCs), which were used beginning in the 1930s in a number of important areas, were determined in 1974 to be responsible for much of the depletion of the ozone layer. Four years later, the EPA and FDA banned CFCs in aerosol cans. As research in the 1980s indicated that the problem was worse than before, and revealed a controversial massive hole in the ozone layer over Antarctica, three international agreements were made to reduce the ozone-damaging substances- the Vienna Convention, the 1987 Montreal Protocol, and a third agreement in 1990 in London. In the United States, title: Cystic fibrosis text: discovered abnormalities in sweat electrolytes; a sweat test was developed and improved over the next decade. The first linkage between CF and another marker (Paroxonase) was found in 1985 by Hans Eiberg, indicating that only one locus exists for CF. In 1988, the first mutation for CF, ΔF508 was discovered by Francis Collins, Lap-Chee Tsui, and John R. Riordan on the seventh chromosome. Subsequent research has found over 1,000 different mutations that cause CF. Because mutations in the "CFTR" gene are typically small, classical genetics techniques had been unable to accurately pinpoint the mutated gene. Using protein markers, gene-linkage studies title: History of chronic fatigue syndrome text: their findings, then later conducted a study and published a paper that refuted the hypothesis. In the United Kingdom, the Chief Medical Officer Kenneth Calman requested a report from the medical Royal Colleges in 1996. This led to the publication of a joint report in which the term "chronic fatigue syndrome" was found to be most representative. This was followed in 2002 by a further report by the new CMO, Liam Donaldson. The U.S. Centers for Disease Control & Prevention (CDC) recognize CFS as a serious illness, and launched a campaign in June 2006 to raise public and medical awareness title: Chlorofluorocarbon text: important to human safety for restriction. Since the late 1970s, the use of CFCs has been heavily regulated because of their destructive effects on the ozone layer. After the development of his electron capture detector, James Lovelock was the first to detect the widespread presence of CFCs in the air, finding a mole fraction of 60 ppt of CFC-11 over Ireland. In a self-funded research expedition ending in 1973, Lovelock went on to measure CFC-11 in both the Arctic and Antarctic, finding the presence of the gas in each of 50 air samples collected, and concluding that CFCs are not title: Chlorofluorocarbon text: hazardous to the environment. The experiment did however provide the first useful data on the presence of CFCs in the atmosphere. The damage caused by CFCs was discovered by Sherry Rowland and Mario Molina who, after hearing a lecture on the subject of Lovelock's work, embarked on research resulting in the first publication suggesting the connection in 1974. It turns out that one of CFCs' most attractive features—their low reactivity— is key to their most destructive effects. CFCs' lack of reactivity gives them a lifespan that can exceed 100 years, giving them time to diffuse into the upper stratosphere. Once