who developed a set of postulates to prove that specific microorganisms cause disease
Robert Koch Friedrich Loeffler
title: Koch's postulates text: Koch's postulates Koch's postulates () are four criteria designed to establish a causative relationship between a microbe and a disease. The postulates were formulated by Robert Koch and Friedrich Loeffler in 1884, based on earlier concepts described by Jakob Henle, and refined and published by Koch in 1890. Koch applied the postulates to describe the etiology of cholera and tuberculosis, but they have been controversially generalized to other diseases. These postulates were generated prior to understanding of modern concepts in microbial pathogenesis that cannot be examined using Koch's postulates, including viruses (which are obligate cellular parasites) or asymptomatic carriers. They title: Bacteria text: not bacteria, but rather fungi.) Along with his contemporary Robert Koch, Pasteur was an early advocate of the germ theory of disease. Robert Koch, a pioneer in medical microbiology, worked on cholera, anthrax and tuberculosis. In his research into tuberculosis Koch finally proved the germ theory, for which he received a Nobel Prize in 1905. In "Koch's postulates", he set out criteria to test if an organism is the cause of a disease, and these postulates are still used today. Ferdinand Cohn is said to be a founder of bacteriology, studying bacteria from 1870. Cohn was the first to classify title: Koch's postulates text: into account prion diseases, which have no nucleic acid sequences of their own. Koch's postulates Koch's postulates () are four criteria designed to establish a causative relationship between a microbe and a disease. The postulates were formulated by Robert Koch and Friedrich Loeffler in 1884, based on earlier concepts described by Jakob Henle, and refined and published by Koch in 1890. Koch applied the postulates to describe the etiology of cholera and tuberculosis, but they have been controversially generalized to other diseases. These postulates were generated prior to understanding of modern concepts in microbial pathogenesis that cannot be examined using title: Robert Koch text: Robert Koch Heinrich Hermann Robert Koch (; ; 11 December 1843 – 27 May 1910) was a German physician and microbiologist. As the founder of modern bacteriology, he identified the specific causative agents of tuberculosis, cholera, and anthrax and gave experimental support for the concept of infectious disease, which included experiments on humans and animals. Koch created and improved laboratory technologies and techniques in the field of microbiology, and made key discoveries in public health. His research led to the creation of Koch's postulates, a series of four generalized principles linking specific microorganisms to specific diseases that remain today the title: Germ theory of disease text: discovered that another serious disease of silkworms, "pébrine", was caused by a small microscopic organism now known as "Nosema bombycis" (1870). Pasteur saved France's silk industry by developing a method to screen silkworms eggs for those that were not infected, a method that is still used today to control this and other silkworm diseases. Robert Koch is known for developing four basic criteria (known as Koch's postulates) for demonstrating, in a scientifically sound manner, that a disease is caused by a particular organism. These postulates grew out of his seminal work with anthrax using purified cultures of the pathogen that