who said the poison is in the dose
credited to Paracelsus Paracelsus
title: The dose makes the poison text: The dose makes the poison "The dose makes the poison" () is an adage intended to indicate a basic principle of toxicology. It is credited to Paracelsus who expressed the classic toxicology maxim "All things are poison, and nothing is without poison, the dosage alone makes it so a thing is not a poison." This is often condensed to: "The dose makes the poison" or in Latin, . It means that a substance can produce the harmful effect associated with its toxic properties only if it reaches a susceptible biological system within the body in a high enough concentration (i.e., title: The Dose Makes the Poison text: adviser to the American Council on Science and Health in New York. Patricia Frank, a consultant and President of Patricia Frank & Associates, Inc., helped edit the third edition. Her firm works with other companies to develop and register pharmaceutical agents for use with humans and animals. Frank is a member and former president of the American College of Toxicology and Roundtable of Toxicology Consultants. "The Dose Makes the Poison: A Plain-Language Guide to Toxicology", written by Ottoboni, in its first and second editions, focused mainly on environmental and industrial chemicals. The author, defining toxicology as "the study of adverse title: Poison text: In modern society, cases of suspicious death elicit the attention of the Coroner's office and forensic investigators. While arsenic is a naturally occurring environmental poison, its artificial concentrate was once nicknamed inheritance powder. In Medieval Europe, it was common for monarchs to employ personal food tasters to thwart royal assassination, in the dawning age of the Apothecary. Of increasing concern since the isolation of natural radium by Marie and Pierre Curie in 1898—and the subsequent advent of nuclear physics and nuclear technologies—are radiological poisons. These are associated with ionizing radiation, a mode of toxicity quite distinct from chemically active poisons. title: The dose makes the poison text: already have significant chronic effects if there is a long-term exposure. Many pollutants, drugs, and natural substances adhere to this principle by causing different effects at different levels, which can as a result lead to health standards that are either too strong or too weak. Generally the effects of different doses can be very different at different levels (not only bigger and smaller impacts depending on dose). The dose makes the poison "The dose makes the poison" () is an adage intended to indicate a basic principle of toxicology. It is credited to Paracelsus who expressed the classic toxicology maxim title: Mithridate text: Mithridate Mithridate, also known as mithridatium, mithridatum, or mithridaticum, is a semi-mythical remedy with as many as 65 ingredients, used as an antidote for poisoning, and said to be created by Mithridates VI Eupator of Pontus in the 1st century BC. It was one of the most complex, highly sought-after drugs during the Middle Ages and Renaissance, particularly in Italy and France, where it was in continual use for centuries. An updated recipe called theriac (Theriacum Andromachi) was known well into the 19th century. Mithridate takes its name from its inventor, Mithridates VI, King of Pontus (134 to 63 BC)