what causes cracked skin at the corners of your mouth
allergies infection irritation
title: Severe cutaneous adverse reactions text: Severe cutaneous adverse reactions Severe cutaneous adverse reactions or SCARs are a group of potentially lethal adverse drug reactions that involve the skin and mucous membranes of various body openings such as the eyes, ears, and inside the nose, mouth, and lips. In more severe cases, SCARs also involves serious damage to internal organs. SCARs includes five syndromes: Drug reaction with eosinophilia and systemic symptoms (i.e. DRESS syndrome, also termed Drug-induced hypersensitivity syndrome [DIHS]); Steven Johnson syndrome (SJS); Toxic epidermal necrolysis (TEN), Stevens-Johnson/toxic epidermal necrolysis overlap syndrome (SJS/TEN); and Acute generalized exanthematous pustulosis (AGEP). The five disorders have similar pathophysiologies, title: Yaws text: Yaws Yaws is a tropical infection of the skin, bones and joints caused by the spirochete bacterium "Treponema pallidum pertenue". The disease begins with a round, hard swelling of the skin, 2 to 5 centimeters in diameter. The center may break open and form an ulcer. This initial skin lesion typically heals after three to six months. After weeks to years, joints and bones may become painful, fatigue may develop, and new skin lesions may appear. The skin of the palms of the hands and the soles of the feet may become thick and break open. The bones (especially those title: Melkersson–Rosenthal syndrome text: Melkersson–Rosenthal syndrome Melkersson–Rosenthal syndrome (also termed "Miescher-Melkersson-Rosenthal syndrome"), is a rare neurological disorder characterized by recurring facial paralysis, swelling of the face and lips (usually the upper lip - cheilitis granulomatosis) and the development of folds and furrows in the tongue (fissured tongue). Onset is in childhood or early adolescence. After recurrent attacks (ranging from days to years in between), swelling may persist and increase, eventually becoming permanent. The lip may become hard, cracked, and fissured with a reddish-brown discoloration. The cause of Melkersson–Rosenthal syndrome is unknown, but there may be a genetic predisposition. It has been noted to be title: Mouth infection text: that drain into a reservoir of deoxygenated blood called the cavernous sinus. Once the infection has spread to the cavernous sinus, it can compress important nerves (cranial nerves III, IV, V1, V2, and VI) within this space and obstruct venous drainage from the upper face. The main symptoms are swelling and pain of both eyes, fever, changes in vision, and headaches. On exam, redness and decreased range of motion of the eyes are present in about 90% of cases. Treatment includes antibiotics and antithrombotics to treat the infection and blood clot. This is a serious complication that leads to death title: Angular cheilitis text: for between 0.7 – 3.8% of oral mucosal lesions in adults and between 0.2 – 15.1% in children, though overall it occurs most commonly in adults in the third to sixth decades of life. It occurs worldwide, and both males and females are affected. Angular cheilitis is the most common presentation of fungal and bacterial infections of the lips. The term "angular cheilitis" is from Ancient greek, "χείλος" meaning lip and -itis meaning inflammation. Angular cheilitis Angular cheilitis (AC) is inflammation of one or both corners of the mouth. Often the corners are red with skin breakdown and crusting. It