Question: Under what condition, in addition to UICC initialization, is the profile download instruction sent by the Mobile Equipment (ME) to the Universal Integrated Circuit Card (UICC) if the terminal supports class 's'?
Option 1: When the User Equipment (UE) experiences a change in network coverage.
Option 2: When the Terminal Equipment (TE) accessing USAT functionalities over the AT interface is connected, disconnected, or changes its profile.
Option 3: When a handover occurs from one base station to another within the same network.
Option 4: When the ME undergoes a software update.
Explanation: According to specifications for class 's' support, the profile download instruction is sent not only during UICC initialization but also in response to changes in the Terminal Equipment's (TE) connection status or profile updates, ensuring UICC and ME capabilities are synchronized under these conditions for seamless USAT functionality access over the AT interface.