Automated Mosquito Salivary Gland Extractor for PfSPZ-based Malaria Vaccine Production
Wanze Li Zhuohong He Parth Vora Yanzhou Wang Balazs Vagvolgyi Simon Leonard Anna Goodridge Iulian Iordachita Stephen L. Hoffman Sumana Chakravarty Russell H. Taylor Wanze Li Zhuohong He Parth Vora Yanzhou Wang Balazs Vagvolgyi Simon Leonard Anna Goodridge Iulian Iordachita Stephen L. Hoffman Sumana Chakravarty Russell H. Taylor
Malaria is a worldwide scourge, and the broad deployment of an effective vaccine would improve the lives of millions of people. A vaccine based on Plasmodium falciparum (PfSPZ) sporozoites extracted from the salivary glands of infected mosquitoes shows significant promise. However, the large-scale industrial production of PfSPZ-based vaccines will benefit from automation of the key step of extract...