['We', 'then', 'apply', 'the', 'coupled', 'approach', 'to', 'biochemical', 'and', 'mechanical', 'conditions', 'typical', 'for', 'postmenopausal', 'osteoporosis', '(', 'Section', '4', ')', 'and', 'microgravity', 'exposure', '(', 'Section', '5', ')', ',', 'and', 'discuss', 'key', 'sensitivity', 'features', '(', 'Section', '6', ')', '.']