['Moreover', ',', 'a', 'previous', 'study', 'had', 'demonstrated', 'that', 'different', 'liposomes', 'with', 'CpG', 'ODN', 'significantly', 'increased', 'Th1', '-', 'biased', 'cytokines', 'and', 'augmented', 'cell', 'mediated', 'immune', 'response', '[', '30', ']', '.']