Why is DataFrame.loc[[1]] 1,800x slower than df.ix [[1]] and 3,500x than df.loc[1]?
import pandas as pd
s=pd.Series(xrange(5000000))
%timeit s.loc[[0]] # You need pandas 0.15.1 or newer for it to be that slow
1 loops, best of 3: 445 ms per loop

Also see the question and the answer here: http://stackoverflow.com/questions/27596832/why-is-dataframe-loc1-1-800x-slower-than-df-ix-1-and-3-500x-than-df-loc

Since .loc[] started to raise KeyError in pandas 0.15.1, the calls via `.loc[ [1] ]` (when passed a list) have slowed down enormously, because, I think, an exhaustive search is done to determine if a KeyError has to be raised or not, even if the list has only one element that can be easily located. 

Profiling:
    File: .../anaconda/lib/python2.7/site-packages/pandas/core/indexing.py,

```
1278                                                       # require at least 1 element in the index
1279         1          241    241.0      0.1              idx = _ensure_index(key)
1280         1       391040 391040.0     99.9              if len(idx) and not idx.isin(ax).any():
1281                                           
1282                                                           raise KeyError("None of [%s] are in the [%s]" %
```
