hand foot and mouth disease began in 1957.
when did hand foot and mouth disease begin?
1957
bullet::::- hfmd infected 1,520,274 people with up to 431 deaths reported at the end of july in 2012 in china.





















































section::::history.





















































hfmd cases were first described clinically in canada and new zealand in 1957. the disease was termed "hand foot and mouth disease", by thomas henry flewett, after a similar outbreak in 1960.





















































section::::research.





















































novel antiviral agents to prevent and treat infection with the viruses responsible for hfmd are currently under development. preliminary studies have shown inhibitors of the ev-71 viral capsid to have potent antiviral activity.
hand, foot, and mouth disease
bullet::::3. hand foot and mouth disease: similar to herpangina, hand foot and mouth disease occurs predominantly in children. it is caused by coxsackie a and b virus, and lesions or blisters are found bilaterally on the hands, feet and mouth of the patient.





















































bullet::::4. oral candidiasis: also known as thrush, herpetic gingivostomatitis can often be differentiated from these microorganism/bacterial causing white plaques on the palate, buccal mucosa, tongue, oropharynx etc.
herpetic gingivostomatitis