beta cells are the cells in the islets of langerhans that produce insulin.
cells in the islets of langerhans that produce insulin?
beta cells
the insulin concentration in blood increases after meals and gradually returns to basal levels during the next 1–2 hours. however, the basal insulin level is not stable. it oscillates with a regular period of 3-6 min. after a meal the amplitude of these oscillations increases but the periodicity remains constant. the oscillations are believed to be important for insulin sensitivity by preventing downregulation of insulin receptors in target cells. such downregulation underlies insulin resistance, which is common in type 2 diabetes. it would therefore be advantageous to administer insulin to diabetic patients in a manner mimicking the natural oscillations. the insulin oscillations are generated by pulsatile release of the hormone from the pancreas. insulin originates from beta cells located in the islets of langerhans. since each islet contains up to 2000 beta cells and there are one million islets in the pancreas it is apparent that pulsatile secretion requires sophisticated synchronization both within and among the islets of langerhans.
insulin oscillation
paul langerhans





























paul langerhans (25 july 1847 – 20 july 1888) was a german pathologist, physiologist and biologist, credited with the discovery of the cells that secrete insulin, named after him as the islets of langerhans.





























section::::eponymous terms.





























bullet::::- islets of langerhans – pancreatic cells which produce insulin. langerhans discovered these cells during his studies for his doctorate at the berlin pathological institute in 1869.
paul langerhans