galway won the shc all-ireland final in 2016.
who won the shc all-ireland final in 2016?
galway
bullet::::- cork 1-40 – 0-20 westmeath (preliminary quarter-final)





























bullet::::- most goals in a match: 5





























bullet::::- kilkenny 2-22 – 3-20 galway (leinster shc)





























bullet::::- kilkenny 2-27 – 3-18 cork (quarter-final)





























bullet::::- most points in a match: 60





























bullet::::- cork 1-40 – 0-20 westmeath (preliminary quarter-final)





























bullet::::- most goals by one team in a match: 3





























bullet::::- carlow 1-14 – 3-22 kilkenny (leinster shc)





























bullet::::- clare 0-17 – 3-21 tipperary (munster shc)





























bullet::::- kilkenny 2-22 – 3-20 galway (leinster shc)





























bullet::::- kilkenny 2-27 – 3-18 cork (quarter-final)





























bullet::::- tipperary 1-28 – 3-20 wexford (semi-final)





























bullet::::- most goals without winning: 3
2019 all-ireland senior hurling championship
though constitutive activation of janus kinase 3 (jak3) leads to different cancers, the mechanism of trans-molecular regulation of jak3 activation is only recently reported. this study showed that jak3 auto-phosphorylation was the rate limiting step during jak3 trans-phosphorylation of shc where jak3 directly phosphorylated (p) two tyrosine residues in sh-2-domain, and one tyrosine residue each in ch-1, and pid domains of shc. direct interactions between mutants of jak3 and shc showed that while ferm domain of jak3 was sufficient for binding to shc, ch-1 and pid domains of shc were responsible for binding to jak3. functionally, jak3 was auto-phosphorylated under il-2 stimulation in epithelial cells. however, shc recruited tyrosine phosphatase shp-2 and ptp-1b to jak3 and thereby dephosphorylate jak3. thus the study not only characterized jak3 interaction with shc, but also demonstrated the mechanism of intracellular regulation of jak3 activation where jak3 interactions with shc acted as a regulator of jak3 dephosphorylation through direct interactions of shc with both jak3 and tyrosine phosphatases.
janus kinase 3