claim: adjuvant-free nanofiber vaccine induces in situ lung dendritic cell activation and th17 responses
evidence_1: these observations are congruent with the conclusion of independent priming by intranasal eαq11 nanofibers of cd4+ t cells in the lung.", "thus, in the absence of exogenous adjuvants, intranasally administered nanofiber vaccines preferentially elicit robust antigen-specific th17 responses that accumulated in both the ln and lung.", "during primary immune responses elicited by pathogens such as gram-negative bacteria, il-17 at the lung mucosal surface is produced by natural killer (nk) cells, γδ t cells, and group 3 innate lymphoid cells (ilcs) [reviewed in ( 35)]."
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  )