claim: mosaic rbd nanoparticles elicit neutralizing antibodies against gps-cov-2 and zoonotic coronaviruses
evidence_1: mice immunized with rbd-nanoparticles, but not soluble antigen, elicited cross-reactive antibody binding and neutralization responses, confirming increased immunogenicity from multimerization.", "mosaic-rbd-nanoparticles elicited antibodies with superior cross-reactive recognition of heterologous rbds compared to sera from immunizations with homotypic sars-cov-2rbd-nanoparticles or antibodies from covid-19 convalescent human plasmas.", "thus, a single immunization with mosaic-rbd- nanoparticles provides a potential strategy to simultaneously protect against sars-cov-2 and emerging zoonotic coronaviruses."
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
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