claim: high expression of angiotensin-converting enzyme-2 on tissue macrophages that cannot be targeted by virus sars-cov-2 in covid-19 patients
evidence_1: consequently, this broad expression of ace2 associated with tmprss2 and furin may explain the high pathogenic potential of sars-cov-2 described in some covid-19 patients with severe multi-organ dysfunction.", "share high expression of angiotensin-converting enzyme-2 (ace2) on tissue macrophages that may be targeted by virus sars-cov-2 in covid-19 patients xiang song, wei hu, haibo yu, laura zhao, yeqian zhao, yong zhao biorxiv 2020.07.18.210120; doi: https://doi.org/10.1101/2020.07.18.210120 share this article: copy citation tools high expression of angiotensin-converting enzyme-2 (ace2) on tissue macrophages that may be targeted by virus sars-cov-2 in covid-19 patients xiang song, wei hu, haibo yu, laura zhao, yeqian zhao, yong zhao biorxiv 2020.07.18.210120; doi: https://doi.org/10.1101/2020.07.18.210120 ", 
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  "these data indicate that alveolar macrophages, as the frontline immune cells, may be directly targeted by the sars-cov-2 infection and therefore need to be considered for the prevention and treatment of covid-19.", "to better understand the pathogenesis of covid-19 and build up the host anti-viral immunity, we examined the levels of ace2 expression on different types of immune cells including tissue macrophages.", "wong, s. k., li, w., moore, m. j., choe, h. & farzan, m. a 193-amino acid fragment of the sars coronavirus s protein efficiently binds angiotensin- converting enzyme 2."
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  )