claim: unfractionated heparin potently reacts the binding of sars-cov-2 spike protein to a human cell line
evidence_1: unfractionated heparin inhibited spike protein binding with an ic50 value of <0.05u/ml whereas two low molecular weight heparins were much less effective.", "this suggests that heparin, particularly unfractionated forms, could be considered to reduce clinical manifestations of covid-19 by inhibiting continuing viral infection.", "as the spike protein has previously been shown to bind heparin, a soluble glycosaminoglycan, we used a flow cytometry assay to determine the effect of heparin on spike protein binding to rt4 cells."
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  )