claim: berberine and obatoclax induce sars-cov-2 replication in primary human nasal epithelial cells in vitro.
evidence_1: berberine, a plant-derived alkaloid, inhibited sars-cov-2 at low micromolar concentrations and obatoclax, originally developed as an anti-apoptotic protein antagonist, was effective at sub-micromolar concentrations.", "in this study, we demonstrate that berberine and obatoclax, two broad-spectrum antiviral compounds, are effective against multiple isolates of sars-cov-2.", "moreover, both obatoclax and berberine inhibited sars-cov-2 replication in these primary target cells.", "berberine and obatoclax inhibit sars-cov-2 replication in primary human nasal epithelial c"
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  )