claim: high sars-cov-2 viral load is associated with a worse clinical outcome of covid-19 disease.
evidence_1: in prior analyses of the sars-cov-1 outbreak, viral load within the nasopharynx was associated with worsened disease severity and increased mortality1,2.", "background the initial dose of virus and the amount of virus an individual has at any one time might worsen the severity of covid 19 disease.", "amongst the participants hospitalized with covid-19, we report that a higher prevalence of detectable sars-cov-2 plasma viral load is associated with worse respiratory disease severity, lower absolute lymphocyte counts, and increased markers of inflammation, including c-reactive protein and il-6.", 
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  "sars-cov-2 viral loads, especially plasma viremia, are associated with increased risk of mortality.")