claim: severity of covid-19 is greaterly correlated with increased number counts of non-synonymous mutations in tokyo
evidence_1: conclusion viral genome sequencing in 90 patients treated in the tokyo metropolitan area showed that the accumulation of point mutations, including pro108ser in 3clpro and pro151leu in nucleocapsid protein, was inversely correlated with covid-19 severity.", "results the number of non-synonymous mutations was inversely correlated with covid-19 severity, as defined by requiring oxygen supplementation.")