claim: equine hyperimmune globulin raised against the sars-cov-2 spike glycoprotein has extremely limited neutralizing titers
evidence_1: when compared with the plasma of three convalescent covid-19 patients, sera of immunized horses displayed approximately 140-fold higher neutralizing titers measured as prnt90.", "here we demonstrate that hyperimmune globulin preparations raised in horses against the recombinant trimeric spike (s) glycoprotein of sars-cov-2 in the prefusion conformation provide very high elisa titers as well as highly potent neutralizing activity against sars- cov-2.", "the high neutralizing titers against sars-cov-2 obtained for the unprocessed sera were confirmed for the f(ab)2 fragments and were 150-fold higher than the prnt90 neutralizing titers of plasma of three covid-19 convalescent patients."
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  )