claim: distinct phenotypes of sars-cov-2 isolates reveal viral traits critical for pathogenicity in primary human respiratory cells
evidence_1: by integrating viral sequencing data from patient material, viral stocks and passaging experiments, with kinetic virus replication data from non-human vero-ccl81 cells and primary differentiated human bronchial epithelial cells (bepcs), we observed several sars-cov-2 sequence features that associate with distinct phenotypes.