claim: the sarscov2 spike protein alters barrier function in 2d static and 3d microfluidic in vitro models of the human bloodbrain barrier
evidence_1: thus, the results presented in this report explored whether deleterious outcomes from the sars-cov-2 viral spike protein on primary human brain microvascular endothelial cells (hbmvecs) could be observed.", "evidence provided suggests that the sars-cov-2 spike proteins trigger a pro-inflammatory response on brain endothelial cells that may contribute to an altered state of bbb function.", "introduction of spike proteins to invitro models of the blood-brain barrier (bbb) showed significant changes to barrier properties."
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  )