claim: ambroxol hydrochloride inhibits the interaction between severe acute respiratory syndrome coronavirus 2 spike protein 's receptor binding domain and recombinant human ace2 .
evidence_1: herein, we discovered that ambroxol hydrochloride (amb), and its progenitor, bromhexine hydrochloride (bhh), both clinically approved drugs are potent effective modulators of the key interaction between the receptor binding domain (rbd) of sars-cov-2 spike protein and human ace2.