claim: serological surveys in reunion island of the first hospitalized patients revealed that long-lived immunoglobulin g antibodies specific against sars-cov2 virus are rapidly vanishing in severe cases
evidence_1: in conclusion, serological testing may be helpful for the diagnosis of patients with negative rt-pcr results and for the identification of asymptomatic cases.", "serological surveys were thoroughly performed over 2 month period by assessing igg and igm responses by immunofluorescence, immunoblot, western blot and conventional elisa using clinical run isolates of sars-cov-2 immobilized on 96 well plates.", "while the igm and, unexpectedly, the igg responses were readily detected early during the course of the disease (5-7 days post-first symptoms), our results (n=3-5 and over the full dilution set of the plasma 1/200 to 1/12800) demonstrated a significant decrease (over 2.5-fold) of igg levels in severe (icu) hospitalized patients (exemplified in patient 1) by wb and elisa."
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  )