claim: sars-cov-2 infection damages airway motile cilia and impairs mucociliary clearance.
evidence_1: we examined the functional and structural consequences of sars-cov-2 infection in a reconstituted human bronchial epithelium model.", "sars-cov-2 reverse genetics reveals a variable infection gradient in the respiratory tract.", "this study identifies cilia damage as a pathogenic mechanism that could facilitate sars- cov-2 spread to the deeper lung parenchyma.", "rather, sars-cov-2 replication led to a rapid loss of the ciliary layer, characterized at the ultrastructural level by axoneme loss and misorientation of remaining basal bodies."
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
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