claim: angiotensin-converting enzyme 2, a sars-cov-2 enzyme, is upregulated by interleukin-6 via stat3 signaling in rheumatoid synovium
evidence_1: our presenting data revealed that ace2 expression was elevated in active rheumatoid synovium, and sirna against stat3 was able to downregulate ace2 expression, which was in turn induced by il-6 signaling.