claim: orf8 and orf3b antibodies are accurate serological markers of early and late sars-cov-2 infection
evidence_1: we identified new targets of the immune response to sars-cov-2 and show that nucleocapsid, open reading frame (orf)8 and orf3b elicit the strongest specific antibody responses.", "we have identified orf8 antibodies as a major marker of acute, convalescent and long-term antibody response to sars-cov-2 infection because of its immunodominance and specificity, in addition to n protein.")