claim: sars-cov-2 receptor ace2 is an interferon-stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues
evidence_1: we identify ace2 and tmprss2 co-expressing cells within lung type ii pneumocytes, ileal absorptive enterocytes, and nasal goblet secretory cells.", "sars-cov-2 spike (s) protein binds angiotensin-converting enzyme 2 (ace2), and in concert with host proteases, principally transmembrane serine protease 2 (tmprss2), promotes cellular entry.", "our data suggest that sars-cov-2 could exploit species- specific interferon-driven upregulation of ace2, a tissue-protective mediator during lung injury, to enhance infection."
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
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