 The cleavage of this chaperone causes cellular stress through protein inhibition, and consequently death of the cell.B subunits of the AB5 toxins have the affinity towards binding glycan which some type of tumors seem to possess making it an easy target.One example is that of StxB which specifically binds with CD77 (Gb3) which shows expression on the surface of cancerous cells such as colon, pancreas, breast, and many more.