 Some of his contributions include the TIP3P, TIP4P, and TIP5P water models, the OPLS force field, and his work on free-energy perturbation theory for modeling reactions in solution, protein-ligand binding, and
drug design; he has over 400 publications in the field.Jorgensen has been the Editor of the ACS Journal of Chemical Theory and Computation since its founding in 2005.Jorgensen earned a Bachelor's degree from Princeton University in 1970 and a Ph.D. from Harvard University in 1975 in Chemical Physics while studying under Elias J. Corey.