 In the Copa Libertadores 2007 Ledesma was a driving force down the right side of midfield for the eventual Champions.Ledesma also scored a clever close-range flick against Colombia's Cúcuta in the Semi Final 1st leg and a brave header at the end of the 1st Leg of the Final against Gremio.After 5 impressive seasons with the Argentine giants, that included well over 100 appearances and 15 total goal, he was monitored by several European clubs, and soon transferred to the Italian Serie A, with Sicilian giants Calcio Catania.