 Interstate 20 also generally heads to the east-northeast passing by the cities of Odessa and Midland while transitioning from the West Texas desert to the prairie.I-20 runs concurrently with the La Entrada al Pacífico corridor from its junction with US 385 in Odessa to its junction with FM 1788 near Midland International Airport.Near Sweetwater, I-20 begins to head east as it heads towards the city of Abilene.