 Euchambersiidae was initially considered to be separate from the families Moschorhinidae and Annatherapsididae; in 1974, Christiane Mendez recognized these groups as closely related subfamilies (renamed Annatherapsidinae, Moschorhininae and Euchambersiinae) within the wider group of her redefined Moschorhinidae (although she also referred to it as Annatherapsididae).The 1986 phylogenetic analysis of James Hopson and Herb Barghusen supported Mendez's hypothesis of three subfamilies within Moschorhinidae, but they elected to use the name Euchambersiidae.In 2009, Adam Huttenlocker and colleagues argued that the names Annatherapsididae, Moschorhinidae, and Euchambersiidae are junior synonyms of Akidnognathidae, since "Akidnognathus" (which also belongs in the same family) was named first before any other member of the family.