 The dosage of brexanolone is progressively adjusted over a range of 30 to 90 μg/kg/hour during this period.Because of the risk of serious harm due to the sudden loss of consciousness, patients must be monitored for excessive sedation and sudden loss of consciousness and have continuous pulse oximetry monitoring (monitors oxygen levels in the blood).While receiving the infusion, people must be accompanied during interactions with their child(ren).