 It is called a subtilase cytotoxin because its A subunit sequence is similar to that of a subtilase-like serine protease in "Bacillus anthracis".Some symptoms caused by this toxin are a decrease in platelet count in the blood or thrombocytopenia, an increase in white blood cell count or leukocytosis, and renal cell damage.The subtilase cytotoxin A subunit (subA, ) is a protease known to cleave binding immunoglobulin protein (BiP), leading to endoplasmic reticulum stress and cell death.