 The first was that, as a result of the amounts of opiates given since January 1950, she was already dying by November that year.The second, the immediate cause of death, was said to be two large injections of an unknown, but presumed lethal, substance prepared by Adams and injected on his instructions into a supposedly unconscious Mrs Morrell on the night of 12 to 13 November 1950, the second an hour before her death.However, on the second day of the trial, the defence produced nurses' notebooks, which showed that smaller quantities of drugs were given to the patient than the prosecution, basing its calculations on Adams' prescriptions, had thought.