 As it is located at 44 Yamate-cho, Naka-ku, the cathedral is commonly known locally as .Immediately after the lifting of the a long-standing ban on Christianity, a Catholic church was built in 1862 by the Paris Foreign Missions Society in the Yokohama foreign settlement (currently Yamashita-cho).This church was moved to its current location in 1906, and was a brick building with two bell towers, which was completely destroyed during the 1923 Great Kantō earthquake.