 During the drinking episode 31% subjects described blackouts, 20% described brownouts, and 49% reported no amnesic episode.Memory disruptions by alcohol leading to blackout have been linked to inhibition of long-term potentiation, particularly in the hippocampus, by affecting gamma-Aminobutyric acid (GABA) and N-methyl-D-aspartate neurotransmission ("see Effects of alcohol on memory").Alcohol induced blackouts are associated with the development of alcohol abuse and dependence, so it is important to consider potential neurobiological risk factors for experiencing this problem prior to onset of substance use.