 Like its more toxic relatives, "Nicandra physalodes" is alkaloidal, analyses having revealed the presence of the tropane alkaloid tropinone and the pyrrolidine alkaloid hygrine (0.1%, in the root).Withanolides are found almost exclusively in plants of the Solanaceae and, while it is noticeable that many psychoactive species belonging to that family contain only, or primarily, such compounds, not a single withanolide has yet been proven to be psychoactive.The compounds are named for the Solanaceous genus "Withania", the best-known species of which, "Withania somnifera", is, as its specific name suggests, mildly psychoactive to the extent of being sleep-inducing (among other useful medicinal properties).