 Bisphenol S (BPS), an analog of BPA, has also been shown to alter estrogenic activity.One study demonstrated that when cultured rat pituitary cells were exposed to low levels of BPS, it altered the estrogen-estradiol signaling pathway and led to the inappropriate release of prolactin.DDT (Dichlorodiphenyltrichloroethane) was widely used in pesticides for agriculture until it was banned in 1972 in the United States due to its hazardous effects on the environment.