"Rabbit Hole" premiered on Broadway at the Biltmore Theatre in a Manhattan Theatre Club production on January 12, 2006 in previews, officially on February 2, 2006 and closed on April 9, 2006 after 77 performances.Directed by Daniel Sullivan, the cast featured Cynthia Nixon (Becca), John Slattery (Howie), Tyne Daly (Nat), John Gallagher, Jr. (Jason) and Mary Catherine Garrison (Izzy).