 Some children with autoimmune lymphoproliferative disorders are heterozygous for a mutation in the gene that codes for the Fas receptor, which is located on the long arm of chromosome 10 at position 24.1, denoted 10q24.1.This gene is member 6 of the TNF-receptor superfamily (TNFRSF6).The Fas receptor contains a death domain and has been shown to play a central role in the physiological regulation of programmed cell death.