 To begin the 2010–11 season, Liles made NHL and franchise history when he recorded an assist in a 4–3 overtime loss to the Vancouver Canucks on October 26, 2010, giving him assists in nine consecutive games to open the season.Despite the Avalanche failing to qualify for the 2011 playoffs, Liles accumulated a career-high 40 assists in 76 games played.On June 24, 2011, Liles was traded by the Avalanche to the Toronto Maple Leafs in exchange for a second-round pick in the 2012 NHL Entry Draft.