 Epstein is best known for serving as the editor of the first complete English translation of the Babylonian Talmud, by the Soncino Press (London, 36 volumes, 1935-1952).He recruited many rabbis and scholars for the massive project, personally reviewing all of the work as it was produced, and co-ordinating the many details of notation and transliteration of Hebrew words.Rabbi Epstein was also an editor of Joseph H. Hertz' "Pentateuch and Haftorahs" (1929–1936), and editor of a collection of papers (published 1935) in connection with the eighth centenary of the birth of Maimonides ( 1135).