 Prompted in part by problems arising from the Tuskegee Syphilis Study (1932–1972) and based on the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research (1974–1978), the Department of Health, Education and Welfare (HEW) revised and expanded its regulations for the protection of human subjects 45 CFR part 46 in the late 1970s and early 1980s.In 1978, the Commission's report "Ethical Principles and Guidelines for the Protection of Human Subjects of Research" was released, and it was published in 1979 in the Federal Register.It was named the "Belmont Report", for the Belmont Conference Center, where the National Commission met when first drafting the report.