 Hypospermia would only usually be a factor in infertility if the two conditions (hypospermia and oligospermia) are combined.The U.S.-based National Institutes of Health defines hypospermia as a semen volume lower than 2 mL on at least two semen analyses.The presence of high levels of fructose (a sugar) is normal in the semen and this comes almost entirely from the seminal vesicles.