 The Överkalix study () was a study conducted on the physiological effects of various environmental factors on transgenerational epigenetic inheritance.The study was conducted utilizing historical records, including harvests and food prices, in Överkalix, a small isolated municipality in northeast Sweden.The study was of 303 probands, 164 men and 139 women, born in 1890, 1905, or 1920, and their 1,818 children and grandchildren.