 He worked on hybridization of plants of similar and different origins, cultivating methods in connection with the natural course of ontogenesis, directing the process of predominance, evaluation and selection of seedlings, and acceleration of the process of selection with the help of physical and chemical factors.Michurin's method of crossing of geographically distant plants would be widely used by other selectionists.He worked out theoretical basis and some practical means for hybridization of geographically distant plants.