 Rather, neutrophils form, the 5,6-epoxide, leukotriene A4 (LTA4), via ALOX5 and passed it to platelets that then reduce it a 5,6-dihydroxy-eicosateteraenoate product and further metabolize it through ALOX12 to form the 15-hydroxy product, LXA4.The two LXs are distinguished form their 15-epi-LTX epimers by their structural formulae