 Other dopamine active medications reported to positively treat stuttering include aripiprazole, asenapine, lurasidone, which tend to be better tolerated than olanzapine with less weight gain.All these medications as well as olanzapine can carry the potential risk of a long-term movement disorder known as tardive dyskinesia.The investigational compound, ecopipam is unique from other dopamine antagonists in that it acts on D1 receptors instead of D2, owing little, if any risk, of movement disorders.