 Consequently, they managed to partially block contact with the West.A revival would begin when Seleucus II's younger son, Antiochus III the Great, took the throne in 223 BC.Although initially unsuccessful in the Fourth Syrian War against Egypt, which led to a defeat at the Battle of Raphia (217 BC), Antiochus would prove himself to be the greatest of the Seleucid rulers after Seleucus I himself.