 Jerome claimed that Demetrius sent Pantaenus on a mission to India, it is likely that Clement succeeded Pantaenus as head of the Catechetical School before the patriarchy of Demetrius.When Clement left Alexandria (c. 203), Demetrius appointed Origen, who was in his eighteenth year, as Clement's successor.Demetrius supported Origen in the beginning of his career, it is said to have admired his scholarship.