 Since 1H dipole-dipole couplings provide the primary means of cross-relaxation or organic molecules in solution, spins undergoing cross-relaxation are those close to one another in space.Therefore, the cross peaks of a NOESY spectrum indicate which protons are close to each other in space.In this respect, the NOESY experiment differs from the COSY experiment that relies on J-coupling to provide spin-spin correlation, and whose cross peaks indicate which 1H's are close to which other 1H's through the chemical bonds of the molecule.