 CEA was created in 1945; since then, the successive high-commissioners have been Frédéric Joliot-Curie, Francis Perrin, Jacques Yvon, Jean Teillac, Raoul Dautry, René Pellat, Bernard Bigot, and Daniel Verwaerde.It conducts fundamental and applied research into many areas, including the design of nuclear reactors, the manufacturing of integrated circuits, the use of radionucleides for curing illnesses, seismology and tsunami propagation, the safety of computerized systems, etc.It has one of the top 100 supercomputers in the world, the "Tera-100".