 The second major roadway is Highway 406 which begins at the QEW in west St. Catharines and ends approximately 30 km south in the city of Welland.Another shorter freeway is Highway 405, named the General Isaac Brock Parkway in 2006.It begins at the QEW in Niagara-on-the-Lake, just east of St. Catharines, and ends about 9 km away at Queenston, Ontario, where it connects to an international bridge that crosses into the United States at Lewiston, New York.