 On January 24, 2016, Grimes was selected to play in the 2016 Pro Bowl after Chris Harris Jr. and Aqib Talib were unable to attend due to the Denver Broncos reaching Super Bowl 50.He earned an overall grade of 74.8 from Pro Football Focus in 2015.On March 7, 2016, Grimes was cut by the Dolphins after he refused to restructure his contract.