 TIAM1 is found in virtually all tumor cell lines examined including B- and T-lymphomas, neuroblastomas, melanomas and carcinomas.T-cell lymphoma invasion and metastasis-inducing protein 1 has been shown to interact with ANK1, Myc, RAC1 and PPP1R9B.Tiam1 interacts also with para-cingulin, that plays a role in recruiting Tiam1 to junctions and thus activate Rac1 at epithelial junctions.