 In addition to LXA4, LTA, RvD1, and FMLP, FPR2 binds a wide range of polypeptides, proteins, and products derived from these polypeptides and proteins.One or more of these various ligands may be involved not only in regulating inflammation but also be involved in the development of obesity, cognitive decline, reproduction, neuroprotection, and cancer.However, the most studied and accepted role for FPR2 receptors is in mediating the actions of the cited lipoxins and resolvins in dampening and resolving a wide range of inflammatory reactions (see lipoxin, Epi-lipoxin, and resolvin).