 Myocilin localises in the Golgi apparatus of corneal fibroblasts and Schlemm's canal endothelial cells.Several isoforms are produced due to post-translational modifications processes including, glycosylation and palmitoylation.The gene undergoes N-glycosylation at the Asn-Glu-Ser site (57–59 amino acids) and O-glycosylation throughout the protein at the Ser-Pro, Pro-Ser, Thr-Xaa-Xaa-Pro, Ser-Xaa-Xaa-Xaa-Pro sites.