 The agents vilazodone and vortioxetine are also partially atypical.Atypical antidepressants are as opposed to typical antidepressants like the , , , and , which act mainly by increasing the levels of the monoamine neurotransmitters serotonin and/or norepinephrine.Among TCAs, trimipramine is an atypical agent in that it does not appear to do this.