 Binding occurs late in the apoptotic process and enhances cytokine production by DCs.In addition, preincubation of apoptotic cells with PTX3 enhances C1q binding and C3 deposition on the cell surface, suggesting a role for PTX3 in the complement-mediated clearance of apoptotic cells.Moreover, in the presence of dying cells, PTX3 restricts the cross presentation of antigens derived from dying cells.