 Manfredi was one of the closest followers of Caravaggio and was at the height of his fame when Seghers arrived in Rome.Seghers fell strongly under the spell of Manfredi's work.He likely also met up with the Dutch and Flemish Caravaggisti residing in Rome such as Gerard van Honthorst, Dirck van Baburen and Jan Janssens and possibly also Hendrik ter Brugghen and Theodoor Rombouts.