 TLR6 has been shown to interact in a heterodimer form with TLR2.Synergistic interactions of TLR2/6 and TLR9 leading to higher resistance against lung infection have also been reported.Unlike TLR2/1 heterodimer, which recognizes triacylated lipopeptides, the TLR2/6 heterodimer is known to be specific for diacylated lipopeptides such as lipoteichoic acid, found on the cell wall of gram-positive bacteria or macrophage-activating lipopeptide (MALP2), found on the cell membrane of mycoplasma.