 This chemokine receptor is special because it bind only one chemokine ligand CCL20 in compare to other chemokine receptors.CCR6 has a key role in connection between immature DC an adaptive immunity.This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dendritic cells and T cells during inflammatory and immunological responses.