 At the time of her early death (at the hands of cholera) on 21 July 1834, she left her husband with nine children to mourn her passing.On 06 May 1853, he married Lady Frances Macnaghten, daughter of John Livingstone Martyn and widow of (i) Lieutenant-Colonel James McClintock of the Bombay Army and (ii) Sir William Hay Macnaghten, British Envoy to Afghanistan who was murdered in Kabul in 1841.Headfort died in December 1870, aged 83, and was succeeded in the marquessate by his son from his first marriage, Thomas.