"Fpr2" and "mFpr-rs1" bind with high affinity and respond to lipoxins but have little or no affinity for, and responsiveness to, formyl peptides; they thereby share key properties with human FPR2;

The large number of mouse compared to human FPR receptors makes it difficult to extrapolate human FPR functions based on genetic (e.g.gene knockout or forced overexpression) or other experimental manipulations of the FPR receptors in mice.