 CYP1B1 is also found in several structures so the eye including, trabecular meshwork and the ciliary body.Differing mutations in the "MYOC" gene have been reported to associate with glaucoma 1, open angle (GLC1A) and glaucoma 3, primary congenital (GLC3A).Glaucoma 1 is a form of primary open-angle glaucoma (POAG), which is characterized based on a specific pattern of defects in the optic nerve, thus causing visual defects.