 RhoA, and the other Rho GTPases, are part of a larger family of related proteins known as the Ras superfamily, a family of proteins involved in the regulation and timing of cell division.RhoA is one of the oldest Rho GTPases, with homologues present in the genomes since 1.5 billion years.As a consequence, RhoA is somehow involved in many cellular processes which emerged throughout evolution.