 The expression of the beta-3 subunit reaches peak at different times in different locations of the brain, during development.The highest expression of Gabrb3 in mice, within the cerebral cortex and hippocampus are reached prenatally, while they are reached postnatally in the cerebellar cortex.After the highest peak of expression, Gabrb3 expression is down-regulated substantially in the thalamus and inferior olivary body of the mouse.