 In mice the Gabrb3 gene is located on chromosome 7 of its genome in a similar gene cluster style with some of the other subunits of the GABAA receptor.GABRB3 encodes a member of the ligand-gated ion channel family.The encoded protein is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for "gamma"-aminobutyric acid, the major inhibitory neurotransmitter of the nervous system.