 Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit beta2 (proteasome subunit beta type-7) in the immunoproteasome.The human PSMB10 gene has 8 exons and locates at chromosome band 16q22.1.The human protein proteasome subunit beta type-8 is 25 kDa in size and composed of 234 amino acids.