 The Collaborative Studies on Genetics of Alcoholism (COGA) group has reported that a single-nucleotide polymorphism in intron 7 of the gamma-aminobutyric acid A a2 receptor (rs279871; GABRA2) was associated with alcohol dependence and marital status.Individuals who had the high-risk GABRA2 variant (i.e., the variant associated with alcohol dependence) were less likely to be married, in part because they were at higher risk for antisocial personality disorder and were less likely to be motivated by a desire to please others.There is also molecular evidence for passive gene–environment correlation.