 HDAC6 is also required in the formation of SG (Stress granule proteins and is instrumental in SG formation; pharmacological inhibition or genetic removal of HDAC6 abolished SG formation.HDAC6 has been shown to interact with HDAC11 and Zinc finger and BTB domain-containing protein 16.HDAC6 interacts with SG (Stress granule) protein G3BP1.