 Arachidonate 8-lipoxygenase

Arachidonate 8-lipoxygenase () is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are arachidonate and oxygen, whereas its product is (5Z,9E,11Z,14Z)-(8R)-8-hydroperoxyicosa-5,9,11,14-tetraenoate.This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases).