 His brothers were prominent architect Alfred Waterhouse, designer of London's Natural History Museum and many other iconic Victorian buildings, and solicitor Theodore Waterhouse, who founded the firm of Waterhouse & Co. that continues to practise in the City of London (now as part of Field Fisher Waterhouse).Edwin Waterhouse was educated at University College School and then its associated university University College London.His memoirs, describing his upbringing, education and professional life, along with his relationship with his two brothers, were found in the firm's archive in 1985, and an edited version produced in 1988.