 A conditional knockout mouse line, called "Hdac3tm1a(EUCOMM)Wtsi" was generated as part of the International Knockout Mouse Consortium program, a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists.Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion.Twenty six tests were carried out on mutant mice and two significant abnormalities were observed.