 Sanjivani narrates a story about four medical interns namely Dr. Juhi Singh, Dr. Rahul Mehra, Dr. Simran Chopra and Dr. Omi Joshi and the trials and tribulations they face to fight a constant battle against diseases and death of patients while balancing their professional and personal life.Sanjeet Bedi playing Dr. Omi quit the series unhappy with the ongoing story but soon returned back in February 2005 for his death sequence when Omi is shown suffering from HIV and dies.It was remade in Bengali as "Ekhane Akash Neel" on Star Jalsha.