 With an insulated frame and a reaction chamber, a bomb calorimeter is used to transfer heat of a reaction or mixing into surrounding water which is then calculated for temperature.A typical solution would use the equation formula_3 (derived from the definition above) in conjunction experimentally determined total-mixture enthalpies and tabulated pure species enthalpies, the difference being equal to enthalpy of mixing.More complex models, such as the Flory-Huggins and UNIFAC models, allow prediction of enthalpies of mixing.