 This class of enzyme is part of a larger superfamily of enzymes known as D-2-hydroxy-acid dehydrogenases.Many organisms from "Hyphomicrobium methylovorum" to humans have some form of the glycerate dehydrogenase protein.There are currently several structures that have been solved for this class of enzyme including those for the two mentioned above with PDB access code , D-glycerate dehydrogenase, and the human homolog Glyoxylate reductase/Hydroxypyruvate reductase (GRHPR), .