 Acetoacetyl-CoA reductase

In enzymology, an acetoacetyl-CoA reductase () is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are (R)-3-hydroxyacyl-CoA and NADP+, whereas its 3 products are 3-oxoacyl-CoA, NADPH, and H+.This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor.