 By blocking nodal in the right side of the embryo, concentrations of nodal remain high only in the left side of the embryo and the nodal cascade cannot be activated in the right side.Because left-right asymmetry is so vital, Cerberus works along with the nodal cilia that push left-determining signal molecules to the left side of the embryo to ensure that the left-right axis is correctly established.Misexpression experiments show that lack of Cerberus expression on the right side can result in situs inversus and cardiovascular malformations.