 Focusing on vaccines, enteric infections and nutrition in young children in disadvantaged communities, she has combined field epidemiology with intensive laboratory investigations to inform both the science of infectious diseases and policy in India.Her comprehensive research on rotavirus has demonstrated the high burden of rotavirus disease across India, the genetic diversity of viruses, the lower protection from infection and vaccines and the exploration of several approaches to improve the performance of oral vaccines.Her work has led to her being described as India's "vaccine godmother".