 The most common in the cattle industry are macrocyclic lactones, which include ivermectin and eprinomectin, benzimidazole, and imidazothiazoles are also used to a lesser extent.Due to routine, blanket herd treatment, there is widespread resistance to anthelmintic drugs in warm climates in sheep, and increasing evidence of resistance in cattle in temperate climates.As a consequence, livestock industries will have to adapt husbandry practices to manage internal parasites.