 Sappington's influence and his wife's connections likely aided the political careers of two of their sons-in-law, Meredith Miles Marmaduke, who married daughter Lavinia in 1826; and Claiborne Fox Jackson, who in 1831 married Jane Breathitt Sappington (named for her mother).She died a few months later.After serving in the Black Hawk War, Jackson married her sister Louisa in 1833.