 This observation encourages neocentromeres to be studied along with their chaperones, to see if neocentromeres may also perhaps have “neo-chaperones” accompanying them.Other phenomena or studies, that may or may not be explicitly related to neocentromeres, may pertain to connections that have not been made in scientific literature yet.Holocentromeres, which are point centromeres distributed throughout the chromosome, have been most extensively studied in worms, "C. elegans".