 This man became known by his pseudonym as the writer Mark Twain.Together with Willoughby D. Miller, who set up in 1890 the pioneering and still valid theory that bacteria of the oral flora degrade carbohydrates to acids, that damage the enamel and allow bacteria to access and destroy the dentin by caries, Jenkins developed a toothpaste and named it Kolynos, the first toothpaste containing disinfectants.The name´s origin is Greek "Kolyo nosos" (κωλύω νόσος), meaning "disease prevention".