 Tritschler's mother died when he was three, and his father was elderly, so he sent a young Guillermo to be educated by his maternal uncle the Rev.Prisciliano Córdova, a prominent cleric of the Diocese of Puebla de los Ángeles.In 1888, he and his brother Alfonso were sent to Rome to study at the Collegio Pio-Latino-Americano Pontificio.