 It may also be analytically helpful to take into account that the centromere is generally defined in relation to the kinetochore, specifically as the “part of the chromosome that links two sister chromatids together via the kinetochore”.However, the emergence of research in neocentromeres troubles this conventional definition and questions the function of a centromere beyond being a “landing pad” for kinetochore formation.This expands the scope of the centromere's function to include regulating the function of the kinetochore and the mitotic spindle.