 One of the earliest examples of Byzantine enamel work is a medallion created in either the late 5th or early 6th century and features a bust portrait of Empress Eudoxia.The period after Iconoclasm saw an upswing in the production of iconic portraits, to which the intricate form of cloisonné developed by the Byzantines lends itself easily.Most enamel works known today have been housed in western Europe since the beginning of the 13th century.