 In 2004, Brown co-founded (along with two of his University of Southampton colleagues) Primerdesign, a company which designs and manufactures products for quantitative Real-time polymerase chain reaction.The company is best known for creating rapid Swine Flu detection kit in 2009, and for creating a test for the SARS-CoV-2 virus strain in 2020.In 2005, Brown founded ATDBio with an aim to synthesize chemically modified oligonucleotides for technical applications.