 Two years later he took his doctorate of philosophy under Jacques Loeb with a thesis on the action of low temperatures on micro-organisms, and was then appointed Assistant Professor of Zoology at the Washington University in St. Louis, Missouri.For three summers he was a member of the staff of instruction in physiology at the Marine Biological Laboratory at Wood's Hole, Massachusetts.He died in St. Louis, after an operation for appendicitis, on March 15, 1904, at the age of twenty-eight.