 On 13 August 2018, Locatelli transferred to Sassuolo on loan with an obligation to buy.In his debut season for the "neroverdi" he made 31 appearances and scored 3 goals (against Catania in Coppa Italia and Cagliari and Chievo Verona in Serie A).With the Italy U-17 team he took part at the 2015 UEFA European Under-17 Championship.